LOCUS       DAVBOM010000001        68088 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBOM010000001 DAVBOM010000000
VERSION     DAVBOM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.001"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ878_000001"
     CDS             <1..116
                     /locus_tag="VQ878_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3094429.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VQ878_000002"
     CDS             135..1652
                     /locus_tag="VQ878_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3094430.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VQ878_000003"
     CDS             1777..3105
                     /locus_tag="VQ878_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3094431.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3358..4224
                     /locus_tag="VQ878_000004"
     CDS             3358..4224
                     /locus_tag="VQ878_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3094432.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4240..5079
                     /locus_tag="VQ878_000005"
     CDS             4240..5079
                     /locus_tag="VQ878_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3094433.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VQ878_000006"
     CDS             5351..5803
                     /locus_tag="VQ878_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3094434.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VQ878_000007"
     CDS             5900..6244
                     /locus_tag="VQ878_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094435.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            6528..7172
                     /locus_tag="VQ878_000008"
     CDS             6528..7172
                     /locus_tag="VQ878_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3094436.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7341..8258
                     /locus_tag="VQ878_000009"
     CDS             7341..8258
                     /locus_tag="VQ878_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3094437.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8276..9160
                     /locus_tag="VQ878_000010"
     CDS             8276..9160
                     /locus_tag="VQ878_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3094438.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9176..10027)
                     /locus_tag="VQ878_000011"
     CDS             complement(9176..10027)
                     /locus_tag="VQ878_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET3094439.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLIDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ878_000012"
     CDS             10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ878_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET3094440.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGN
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12295..12891
                     /gene="recR"
                     /locus_tag="VQ878_000013"
     CDS             12295..12891
                     /gene="recR"
                     /locus_tag="VQ878_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET3094441.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13086..14129
                     /locus_tag="VQ878_000014"
     CDS             13086..14129
                     /locus_tag="VQ878_000014"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET3094442.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFAKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14213..15586
                     /locus_tag="VQ878_000015"
     CDS             14213..15586
                     /locus_tag="VQ878_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET3094443.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGALDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            15573..16184
                     /locus_tag="VQ878_000016"
     CDS             15573..16184
                     /locus_tag="VQ878_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3094444.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            16275..16979
                     /locus_tag="VQ878_000017"
     CDS             16275..16979
                     /locus_tag="VQ878_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET3094445.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ878_000018"
     CDS             17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ878_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET3094446.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ878_000019"
     CDS             18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ878_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET3094447.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19852..20523
                     /locus_tag="VQ878_000020"
     CDS             19852..20523
                     /locus_tag="VQ878_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET3094448.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESSSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20533..21072
                     /locus_tag="VQ878_000021"
     CDS             20533..21072
                     /locus_tag="VQ878_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET3094449.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21072..21335
                     /locus_tag="VQ878_000022"
     CDS             21072..21335
                     /locus_tag="VQ878_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET3094450.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21332..22117
                     /locus_tag="VQ878_000023"
     CDS             21332..22117
                     /locus_tag="VQ878_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET3094451.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ878_000024"
     CDS             22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ878_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET3094452.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23262..26054
                     /locus_tag="VQ878_000025"
     CDS             23262..26054
                     /locus_tag="VQ878_000025"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET3094453.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKNLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            26457..26837
                     /locus_tag="VQ878_000026"
     CDS             26457..26837
                     /locus_tag="VQ878_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094454.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            27031..27321
                     /locus_tag="VQ878_000027"
     CDS             27031..27321
                     /locus_tag="VQ878_000027"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094455.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            27372..28064
                     /locus_tag="VQ878_000028"
     CDS             27372..28064
                     /locus_tag="VQ878_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET3094456.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            28117..30528
                     /locus_tag="VQ878_000029"
     CDS             28117..30528
                     /locus_tag="VQ878_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3094457.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            30778..31479
                     /locus_tag="VQ878_000030"
     CDS             30778..31479
                     /locus_tag="VQ878_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094458.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            31481..34189
                     /locus_tag="VQ878_000031"
     CDS             31481..34189
                     /locus_tag="VQ878_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3094459.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ878_000032"
     CDS             complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ878_000032"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET3094460.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ878_000033"
     CDS             complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ878_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET3094461.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(35860..36708)
                     /locus_tag="VQ878_000034"
     CDS             complement(35860..36708)
                     /locus_tag="VQ878_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3094462.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(36705..37427)
                     /locus_tag="VQ878_000035"
     CDS             complement(36705..37427)
                     /locus_tag="VQ878_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3094463.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            37718..39610
                     /gene="pepO"
                     /locus_tag="VQ878_000036"
     CDS             37718..39610
                     /gene="pepO"
                     /locus_tag="VQ878_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET3094464.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(39733..40362)
                     /locus_tag="VQ878_000037"
     CDS             complement(39733..40362)
                     /locus_tag="VQ878_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3094465.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            41358..43580
                     /locus_tag="VQ878_000038"
     CDS             41358..43580
                     /locus_tag="VQ878_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET3094466.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            43610..44053
                     /locus_tag="VQ878_000039"
     CDS             43610..44053
                     /locus_tag="VQ878_000039"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET3094467.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGFLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(44320..44505)
                     /locus_tag="VQ878_000040"
     CDS             complement(44320..44505)
                     /locus_tag="VQ878_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094468.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(44524..44937)
                     /locus_tag="VQ878_000041"
     CDS             complement(44524..44937)
                     /locus_tag="VQ878_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094469.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(45068..45715)
                     /locus_tag="VQ878_000042"
     CDS             complement(45068..45715)
                     /locus_tag="VQ878_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HET3094470.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAPIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVRNDEEVR"
     gene            complement(45741..45932)
                     /locus_tag="VQ878_000043"
     CDS             complement(45741..45932)
                     /locus_tag="VQ878_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094471.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGVRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(45913..46563)
                     /locus_tag="VQ878_000044"
     CDS             complement(45913..46563)
                     /locus_tag="VQ878_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET3094472.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            46675..47517
                     /locus_tag="VQ878_000045"
     CDS             46675..47517
                     /locus_tag="VQ878_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3094473.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            47593..48030
                     /locus_tag="VQ878_000046"
     CDS             47593..48030
                     /locus_tag="VQ878_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET3094474.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            48098..48400
                     /locus_tag="VQ878_000047"
     CDS             48098..48400
                     /locus_tag="VQ878_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094475.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(48491..49564)
                     /locus_tag="VQ878_000048"
     CDS             complement(48491..49564)
                     /locus_tag="VQ878_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET3094476.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            49720..50397
                     /locus_tag="VQ878_000049"
     CDS             49720..50397
                     /locus_tag="VQ878_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3094477.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            50390..51364
                     /locus_tag="VQ878_000050"
     CDS             50390..51364
                     /locus_tag="VQ878_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3094478.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ878_000051"
     CDS             complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ878_000051"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET3094479.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFIISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(53414..53737)
                     /locus_tag="VQ878_000052"
     CDS             complement(53414..53737)
                     /locus_tag="VQ878_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET3094480.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            54596..55225
                     /locus_tag="VQ878_000053"
     CDS             54596..55225
                     /locus_tag="VQ878_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET3094481.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ878_000054"
     CDS             55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ878_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET3094482.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            56451..57065
                     /locus_tag="VQ878_000055"
     CDS             56451..57065
                     /locus_tag="VQ878_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET3094483.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(57358..58107)
                     /locus_tag="VQ878_000056"
     CDS             complement(57358..58107)
                     /locus_tag="VQ878_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET3094484.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            58240..60576
                     /locus_tag="VQ878_000057"
     CDS             58240..60576
                     /locus_tag="VQ878_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET3094485.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            61105..62568
                     /locus_tag="VQ878_000058"
     CDS             61105..62568
                     /locus_tag="VQ878_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3094486.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            62561..62989
                     /locus_tag="VQ878_000059"
     CDS             62561..62989
                     /locus_tag="VQ878_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3094487.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            62967..63416
                     /locus_tag="VQ878_000060"
     CDS             62967..63416
                     /locus_tag="VQ878_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3094488.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            63444..63755
                     /locus_tag="VQ878_000061"
     CDS             63444..63755
                     /locus_tag="VQ878_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET3094489.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            63781..64866
                     /locus_tag="VQ878_000062"
     CDS             63781..64866
                     /locus_tag="VQ878_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET3094490.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            64877..65572
                     /locus_tag="VQ878_000063"
     CDS             64877..65572
                     /locus_tag="VQ878_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3094491.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            65609..67579
                     /gene="tkt"
                     /locus_tag="VQ878_000064"
     CDS             65609..67579
                     /gene="tkt"
                     /locus_tag="VQ878_000064"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3094492.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            67952..>68088
                     /locus_tag="VQ878_000065"
     CDS             67952..>68088
                     /locus_tag="VQ878_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3094493.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YG"
BASE COUNT        20138 a        12448 c        15285 g        20217 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgagac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cggatttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac gctttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cggatgcttt gaaagccttc
     3061 actgaaaaag caaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 tgaaaaagta attttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     3181 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     3241 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     3301 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     3361 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     3421 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     3481 tttgagtttg tgggcttaga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     3541 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     3601 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     3661 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     3721 tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     3781 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     3841 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     3901 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ctggaagatt
     3961 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     4021 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     4081 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     4141 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     4201 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     4261 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     4321 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     4381 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     4441 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     4501 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     4561 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     4621 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     4681 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     4741 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     4801 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     4861 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     4921 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     4981 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
     5041 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
     5101 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctggtaga
     5581 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgactgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
     5701 taattttgcg attttcttcc caggtgagcc acatcagcca actggctatg caggtatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagcatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aatggcattg tgaatgcatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatagcacg
     6061 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattac tgaccaagat
     6121 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtactat
     6361 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
     6421 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
     6481 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
     6541 gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt tttagtgaga
     6601 aggtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
     6661 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
     6721 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
     6781 agttaggtct gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt
     6841 ggggtcaaac agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt
     6901 tccttacgat tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga
     6961 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
     7021 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctactct
     7081 taggtggctc agtcttcctg ctttttgggt ttggactatt ggtctttatc cagactggat
     7141 tgatggagaa aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa
     7201 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
     7261 agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
     7321 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
     7381 tctacgcatg ttatgatgag caaggagaag taagtccaga gcgtacgcgt gccttggttc
     7441 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
     7501 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
     7561 gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg
     7621 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
     7681 gcttgccaga atactcagtt gccaaatact ggaacgatat tagttctgca gctccaaaca
     7741 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
     7801 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
     7861 aagatatcca aacctttgtc agccttggcg gggaagacca tattgtcttt aacggtccag
     7921 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
     7981 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
     8041 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
     8101 gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg aatattggat
     8161 ctgttcgttc accattgaca ccagtaactg aagaagatcg tccagttgta gaagcggctg
     8221 cagccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
     8281 atactacgtt gcaattgata tcggtggaac taacatcaag tatggtttgg ttgatcaaga
     8341 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
     8401 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt
     8461 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
     8521 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
     8581 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
     8641 aggcaaggga gcaagtgtga cactttgctt gaccattgga acaggtatcg gtggttgctt
     8701 gattatggat aggaaagtct tccatggttt tagtaattca gcctgtgaag tcgggtatat
     8761 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
     8821 agctgaagcc catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc
     8881 tactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
     8941 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
     9001 catggggcaa gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggctttggt
     9061 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
     9121 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
     9181 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
     9241 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
     9301 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
     9361 tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga
     9421 gtacagtctt tgcccccatc tccttggcat ctattagact atctaaaata gaaggagttg
     9481 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
     9541 caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt
     9601 tcatttcacg ggcgacgagg ccagaactcc ctgttccgaa gaagtagata cgctcagcat
     9661 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
     9721 ccctcatgtt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
     9781 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
     9841 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
     9901 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
     9961 cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    10021 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    10081 acacttcatt ataacacata atataaggat agataaataa aaacgcatct ctgttttaaa
    10141 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    10201 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    10261 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    10321 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    10381 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    10441 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    10501 aaatgacagc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    10561 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    10621 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc
    10681 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt caactaaact
    10741 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    10801 ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct gttattgcct
    10861 ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg
    10921 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    10981 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacttcct
    11041 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc
    11101 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    11161 atatcaaact gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt
    11221 atttcaattc cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    11281 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    11341 cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    11401 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    11461 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    11521 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    11581 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    11641 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    11701 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    11761 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    11821 agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg
    11881 ttgaaggcat ttatggtaat aatgataagg gaggactggg taacttgatt cagcaactgc
    11941 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    12001 gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc ttttcaaatg
    12061 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    12121 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    12181 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc
    12241 gtgacattat caatctgtat caaaaatacc atccaatgaa ttagaaagga aattatgctt
    12301 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    12361 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    12421 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    12481 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    12541 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    12601 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    12661 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    12721 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    12781 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    12841 gcggacgaag tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca
    12901 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc
    12961 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    13021 tgatatacta aagagcgagt attctagtag aattaggaca aataagtaga attaggacaa
    13081 ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct
    13141 ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga
    13201 ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg
    13261 ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa
    13321 gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag
    13381 atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt
    13441 tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta
    13501 ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg
    13561 aagtggaaga aaaattggct tatccagtct tcgctaagcc gtcaaacatg gggtctagtg
    13621 tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc
    13681 gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc
    13741 tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct
    13801 tttatgacta cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa
    13861 tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg
    13921 gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca
    13981 acgagctcaa taccatgcca ggtttcaccc agtggtctat gtacccacta ctttgggaca
    14041 atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt
    14101 ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc
    14161 actgcaaggt gactagagtt ctcggacttc gccccttttt aaaggagtag aaatgaaatt
    14221 aacaatctat gaagttgccc aagctgttgg agctaaaaat gatgttagtc tttttgcgga
    14281 cgcccagtta gaaaaggctg agtttgacag tcgattgatt gggactggag atttatttgt
    14341 gccacttaaa ggtgcgcttg atggccatga ctttattgaa acagcctttg aaaatggtgc
    14401 agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt
    14461 tttgacagcc tttcaatcct tagcatccta ctatcttgaa aaaacgactg ttgatgtctt
    14521 tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc
    14581 aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta
    14641 cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg gacaggatca
    14701 cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt
    14761 ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat
    14821 gcaaattgca gacggaatgg cttcaggttc cttgctttta acgccggctg accctatcgt
    14881 agaggactat ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga
    14941 aatcacagac ttggttgagc gtaaggacag tctgaccttt aaggctaatt tcttggaaca
    15001 agcccttgat ttgccagtga ctggtaagta caatgctacc aatgctatga ttgcgtccta
    15061 tgttgcccta caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga
    15121 attgacgcgt aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga
    15181 cgtatataat gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc
    15241 agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca
    15301 gtctattcaa ctccataacc agataatttt gagcctttct ccagatgtgc ttgataccgt
    15361 tattttctat ggagaagaca ttgctgaatt agcccaactt gctagtcaaa tgttcccaat
    15421 cggacacgtt tattacttca agaaaacaga agaccaagac caatttgaag acctagttaa
    15481 gcaggtcaaa gaaagccttg gggctcatga ccaaatcctg ctcaaaggct ctaactctat
    15541 gaatctagcc aagttggtag aaagtttaga aaatgaagac aagtgatttt gtcaagtatt
    15601 tgcaaagaat gattgccatt acagatactg gcttaacctt tacaaaagat ccgtttgacc
    15661 gtgagcgcta cgaagacttg cgagactttt tatctgaaat gttgaatcaa gcatcagacc
    15721 ttgattccga agaagtggca gaagtcttga agccaacttc tgcttatgcg actccgttaa
    15781 tggacgtccg tgcttggatt gttgaggacg aaaagatttg tctggttagg ggacaaggag
    15841 aggatagttg ggctttgcca ggtggctttg gtgaggttgg ctattctcca acagaaaata
    15901 ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg
    15961 tttttgatac caatcgtttc caactacaga gcaaacagta tacaaagttt gtttttggat
    16021 gtaagcttct cgatggacaa ttccaagaaa atcaagaaat tgctgacctt caattttttg
    16081 ccattgacca actgccgaac ttatctgaaa aacgcattac caaggagcaa atagagcttc
    16141 tttggcaggt ttatcaaggt catagggggc aatatcttga ctaagaagat gattatcgta
    16201 tttctaaatc catttttaac aactagcatg gtataataat atgcaggaaa attttgaatt
    16261 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    16321 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    16381 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg
    16441 ttcagttaat ccttctttat ggttggtact gggttaatca tatgccactg tcagaaagcc
    16501 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    16561 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    16621 cagtgccaga tgcttaccct tttccacata ttaccatttt atcctttatc tttggtcatt
    16681 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    16741 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    16801 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    16861 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    16921 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    16981 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    17041 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    17101 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    17161 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    17221 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    17281 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    17341 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    17401 aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    17461 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    17521 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    17581 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    17641 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    17701 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    17761 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    17821 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    17881 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    17941 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    18001 caaagaaacc ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc
    18061 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    18121 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    18181 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    18241 tgtcccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga
    18301 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    18361 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    18421 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg cgcctacaga
    18481 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    18541 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    18601 ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg
    18661 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    18721 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    18781 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    18841 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    18901 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    18961 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    19021 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    19081 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    19141 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    19201 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    19261 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    19321 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    19381 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    19441 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    19501 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    19561 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    19621 atggttttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    19681 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    19741 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    19801 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    19861 aaagaaaata cagaacttgt ttttcgagaa gttggagagg ctagtctgag tgctcatcga
    19921 gagagtagtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    19981 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    20041 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    20101 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    20161 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    20221 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    20281 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    20341 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    20401 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    20461 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    20521 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    20581 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    20641 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggttgg tacaaaagag
    20701 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    20761 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    20821 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    20881 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    20941 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    21001 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    21061 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    21121 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    21181 gtcgttggat tgtagcgttg gtgaaaccag tacttgctcc cttgcaacgc ctgcctttac
    21241 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    21301 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    21361 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    21421 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    21481 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    21541 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    21601 ccaagaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    21661 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    21721 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    21781 aattggtcgt atacctgttt cgttggagga acgtcctttc accgagaaaa tagataagct
    21841 agaacagtat cgagaactga atttatctgt gtctagtttt cgattagatg ttcttttatc
    21901 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    21961 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    22021 tgtgagaaaa tttggtcgct tgagattatt tcaagataag ggacaaacga aaaaagagaa
    22081 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    22141 ttagaaataa aggacaagac ctttggaact cgattcagag gttttgatcc agaagaagtc
    22201 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    22261 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    22321 tcattgagcc agtctgtatt gattgcccag gatacagctg agagagtgaa acaggcggcg
    22381 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    22441 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    22501 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    22561 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    22621 acagctactt atcttcaaac tagtgatgaa gcctttaaag aagtggttag cgaagtactt
    22681 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    22741 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    22801 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    22861 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    22921 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcatca ggatttgaag
    22981 caccgcaaga atccgttaca attttataag aaacgatgtg agaacaatat cttatcctta
    23041 tatttccagc gagcaggaga tggtgtgagt cctgcattcc ctaacgataa gattatcctc
    23101 tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg ggataagagg
    23161 gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    23221 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagataccc
    23281 ttaatcttgg gaaaacagct ttcccaatgc gtgcaggcct tccgaccaaa gagccagttt
    23341 ggcaaaagga atgggaagat gcaaaacttt accaacgtcg tcaagaacta aatgaaggga
    23401 aaccgcattt tgtcttgcat gatggccctc catacgcaaa cggaaatatc cacgttggac
    23461 atgccatgaa tcatatctca aaagatatca tcattcgttc taagtctatg tcaggtttta
    23521 acgcacctta tatcccaggt tgggatactc atggtctgcc aatcgagcaa gttttggcaa
    23581 agcaaggtgt gaagcgcaaa gaaatggact tggttgagta cttgaaactc tgtcgtgagt
    23641 acgctctttc tcaagtttat aaacaacgtg atgatttcaa acgcttgggg atgtcaggtg
    23701 actgggaaaa tttatatgtg actttaactc cagactatga agcagcccaa atccgtgtct
    23761 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    23821 ggtcatctga gtcagccctt gccgaagcgg aaattgaata ccatgatttg gtttcgactt
    23881 cactttatta tgccaataag gtaaaagatg gcaaaggtat cctagataca gatacttata
    23941 tcgtagtctg gacaacaact ccatttacca tcacagcttc tcgtggtttg actgttggtg
    24001 cagatattga ttacgttttg gttcaacctg ctagtgaaac tcgtaagttt gtcgttgctg
    24061 cagaattgtt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gtgttggcaa
    24121 cttaccgtgg tcaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    24181 atgagttggt aatccttggt gatcacgtta ccactgactc tggtacaggt atcgtccata
    24241 cagcccctgg ttttggtgag gacgactaca atgttggtat tgctaatggt cttgaagtcg
    24301 cagtgactgt tgacgaacgc ggtatcatga tggcgaatgc tggtcctgag tttgaaggtc
    24361 agttctacga caaggttgta ccaactgtta ttgaaaaact tggtaacctc cttctagccc
    24421 aagaagaaat ctctcactca tacccatttg actggcgtac taagaaacca atcatctggc
    24481 gtgcagttcc acaatggttt gcctcagttt caaaattccg ccaagaaatc ttggatgcta
    24541 ttgataaagt taaattccat acagaatggg gtaaagtacg tctatataat atgattcgtg
    24601 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt ccaatcttct
    24661 atgcagaaga cggtacagct atcatgacag ctgagactat tgaacatgtg gcgcaactct
    24721 ttgaagtaca tggttcaagc atttggtggg aacgtgatgc caaaaacctc ttaccagaag
    24781 gatttacaca tccaggttct ccaaatgggg agttcaagaa agaaacagat attatggatg
    24841 tatggtttga ctcaggttca tcatggaatg gtgttttggt aaatcgtcca aatctgactt
    24901 atccagctga cctttacctt gaaggttctg accaataccg tggttggttc aactcatcac
    24961 ttattacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    25021 ttacccttga tggtaaaggt gagaagatgt ctaaatcact tggaaatacc attgctccaa
    25081 gtgatgttga aaaacaattt ggtgcagaaa tcttgcgtct ctgggtaaca agtgttgact
    25141 caagcaatga cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta
    25201 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    25261 atgtagtcgc ttacgatgaa cttcgttcag ttgataagta catgactatt cgctttaacc
    25321 agcttgtcaa gaccattcgt gatgcctatg cggactttga attcttgaca atctacaagg
    25381 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    25441 ttgtttacat tgaaggtgcc aaatcattgg aacgccgtca aatgcagact gttttctatg
    25501 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    25561 tctggtcata tcttgagttt gaagctgaag acttcgttca attgtcagaa ttgccagaag
    25621 ctcaaacttt tgctaatcaa gaagaagtct tggatacatg ggcagccttc atggacttcc
    25681 gtggacaagc tcaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc gggaaatcgc
    25741 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    25801 acagcaatgt ggctcaactt ttgatcgtgt cagacttgac catcgcagaa gggccagctc
    25861 cagaagctgc tgttagcttc gaagatgtag ccttcacagt tgaacgcgct gcaggtcaag
    25921 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca
    25981 tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    26041 ttgaagagaa ataaggttga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    26101 aattttatag tctattaaac gcattgtatc acgtttttga atacctgata tgatgcgttt
    26161 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    26221 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgc
    26281 taaatagtgt aatattttta caataataaa tttatatagt tatttttggt ttctgaaaag
    26341 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    26401 ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat tttattatga
    26461 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
    26521 ttattggtcc ttttgtcttg ttgggaacag cggtaaacac agttgctaca actcttaatg
    26581 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
    26641 caaatcttgt tcttggtatc attgctattg tttactataa aggagataat cgtgtaggtg
    26701 cagctccgtc tgtactaatg attgtttttg gtggagttag tctcattcca ttcttaggat
    26761 gggttggggg gattcttgtt attatcggag gatctctatt ccttgcaaca ttgaagaaat
    26821 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
    26881 ggagtagctc tattatctct ttttcttcta gttgcatgtg gaacataaag ttcaaaggat
    26941 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
    27001 actttcgata caccggttgt aacagacgat gtgattgaat caatacgcac ttatgcagat
    27061 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
    27121 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
    27181 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aactaaaaac
    27241 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
    27301 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
    27361 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
    27421 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
    27481 ttgacgctgg taaattgatc aaagaagctg gtatcaaatt tgaccaagct tacacttcag
    27541 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattgtggg
    27601 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
    27661 ataaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
    27721 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
    27781 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
    27841 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
    27901 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
    27961 cagatgacga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
    28021 acgaaaaatt gaacgtcgtt tctgaatact accttggaaa ataaaaaatt gtaagtctag
    28081 aattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
    28141 tatgtactgg cctacaagca accagtttca accacttaca tgggttggga agaagaagct
    28201 ttaccgatag gcaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
    28261 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
    28321 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
    28381 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
    28441 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
    28501 acgactttgt ctcaggtgac ggactatcag agacagctga atattagtaa ggcacttgtg
    28561 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
    28621 gatgatctct tggttcagcg ttttactaag gaaggggcgg aaactctaga ttttactata
    28681 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
    28741 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
    28801 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
    28861 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
    28921 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
    28981 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
    29041 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc taatgttgac
    29101 gcattcacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
    29161 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
    29221 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
    29281 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
    29341 ctagaggcgg tctttccggt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
    29401 gcggctgtaa agtatgcagg aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt
    29461 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
    29521 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
    29581 gaccaagact atctcaggga gaaaatttat cccatgttga gggaaacggt tcgtttttgg
    29641 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
    29701 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
    29761 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
    29821 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
    29881 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
    29941 cacgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
    30001 tatattgaag cggcacgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
    30061 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
    30121 ttggcagagc agttaaaaac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
    30181 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
    30241 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
    30301 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
    30361 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
    30421 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
    30481 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
    30541 aggcagtaat ttgaaacttc cttttaataa ggatttaaga atataggcag tttccaacta
    30601 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
    30661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
    30721 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
    30781 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
    30841 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
    30901 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
    30961 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
    31021 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
    31081 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
    31141 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
    31201 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattctcctt
    31261 tgtgatgaac cgactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
    31321 caagacatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
    31381 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
    31441 aaccagcatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
    31501 ttggaaggac ttaattcagt ccttcacaga ctccaagggg cgttttttat ccatcttgat
    31561 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
    31621 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
    31681 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
    31741 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
    31801 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacag
    31861 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
    31921 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
    31981 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
    32041 gactctgaca gcctatgggg tgattttacc tagtcaattt gatcagaaag tctacaatat
    32101 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
    32161 aaaatccaag caacatcagg aagaccttga acaaacttta tcagataatg gcaaggtacg
    32221 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agactcttga
    32281 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
    32341 acaggctcaa gaaagtcaac tagccttgtt tcctcaagct cagagagagc aggctagtgc
    32401 tcaacttacc caagccaagc aggaactggg caaggaagag gacaaactaa agcaagctga
    32461 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggatgattt
    32521 ggcggagcca aggtatcagg tttataatcg tcagaccatg ccaggtggtc agggctatct
    32581 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
    32641 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
    32701 aactcatgca gggattttta aggccttggg ttatcgtagt aaggatatta tcgccaagtt
    32761 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
    32821 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
    32881 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
    32941 tgtgttacca gcctatctgg tggcttggag ggaacttcat gacgaagcag cccagcttct
    33001 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
    33061 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
    33121 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
    33181 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
    33241 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
    33301 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
    33361 tttcaagggc agggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
    33421 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
    33481 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
    33541 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
    33601 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
    33661 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
    33721 atctgcggtg tccagtgttg tccaaaatgc ttcagccatt cgactcttcg actctatcgc
    33781 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
    33841 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactat
    33901 caaggttctc ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
    33961 gctgtccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
    34021 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
    34081 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
    34141 ttatctgaga aaggttgaca tgttagaagc cctgaaatct gtagagtaag gtagttattt
    34201 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
    34261 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
    34321 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
    34381 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgcg
    34441 tccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
    34501 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc
    34561 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
    34621 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
    34681 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
    34741 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
    34801 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg tgcatagaaa
    34861 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
    34921 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
    34981 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
    35041 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
    35101 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
    35161 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
    35221 gttacaatga gtttcttttc agcagggatc ttattaaatt tatccttact ttctttatca
    35281 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
    35341 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
    35401 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcaag gtagataaca
    35461 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
    35521 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
    35581 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc
    35641 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
    35701 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
    35761 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
    35821 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
    35881 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
    35941 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
    36001 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatgcttt tcagactatt
    36061 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca ggatagttcc
    36121 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
    36181 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
    36241 ttgcttgaag aaaatccaga ttaacaagag gatggctgcc cccacaccca tagtaataaa
    36301 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
    36361 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    36421 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    36481 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    36541 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    36601 aatgaaacat cccacggctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    36661 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    36721 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    36781 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    36841 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    36901 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    36961 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    37021 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    37081 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    37141 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    37201 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    37261 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    37321 tttggaccaa tgatgccggt aattgttggt ccatggagca ctagtgaaat atccttaagt
    37381 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    37441 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    37501 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    37561 aacgcatagt atcaagtgta aaaaacttgg aattatgcgt tttatcatgg aaagattttt
    37621 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    37681 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    37741 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    37801 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    37861 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    37921 ccaccgccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    37981 actccttaaa gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga
    38041 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    38101 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    38161 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc
    38221 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    38281 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    38341 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    38401 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    38461 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    38521 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    38581 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    38641 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    38701 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    38761 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    38821 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    38881 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    38941 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    39001 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    39061 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    39121 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    39181 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    39241 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    39301 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    39361 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    39421 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    39481 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    39541 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    39601 tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac
    39661 cttgatagga tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt
    39721 gtcatcatct tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg
    39781 accatgtcct ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatactatg
    39841 aaggagttgc tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag
    39901 agcatctccc gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga
    39961 gtgccctggg gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa
    40021 gacaaaggtg tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag
    40081 accggagaga ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac
    40141 aggaggattg ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc
    40201 gtgggtcaag agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc
    40261 ttcccaatga ctaccaggat cgacgacgat taggtgcttt tcgccttcta gataataggt
    40321 attttcatag gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa
    40381 gaatgtacta atactcttcg aaaatctctt caaactgcgt caactttatc tgcaacctca
    40441 aagcagtgct ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag
    40501 tataaattaa gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa
    40561 ccagcatgac tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa
    40621 ttgcccttca taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag
    40681 agtgctaccg tagttggctt ctcgtttgtc gctatattca ctataagtta tcctactggg
    40741 caggttctgg tcgttagcat agtattgaac gactgttttt tatagctttg ctggctgaat
    40801 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc
    40861 ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc
    40921 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg
    40981 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    41041 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    41101 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    41161 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    41221 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    41281 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    41341 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    41401 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    41461 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    41521 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    41581 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    41641 gtcctgatgt gcggatgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    41701 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    41761 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    41821 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    41881 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    41941 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    42001 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    42061 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    42121 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    42181 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    42241 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    42301 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    42361 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    42421 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    42481 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    42541 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt
    42601 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    42661 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    42721 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    42781 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    42841 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    42901 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    42961 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    43021 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    43081 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    43141 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    43201 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    43261 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    43321 actctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    43381 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    43441 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    43501 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    43561 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    43621 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    43681 tcagggattt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    43741 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    43801 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    43861 tactaagaaa ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    43921 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    43981 tggagcagat atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac
    44041 taaaaagaga tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    44101 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    44161 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    44221 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    44281 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    44341 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    44401 caaaatccag tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc
    44461 aatgacaagg agttgaatgg ttttgatgaa tatgattttt ttcatgctaa aacctccttt
    44521 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc
    44581 taggtagtca gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag
    44641 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    44701 gagaatccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    44761 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgatcaa ggaagaaaat
    44821 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    44881 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    44941 aagaccttcc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    45001 atgataaaaa tagcagaggg gagattctct taagttggct agtattcttt atttgagttt
    45061 ccttctatta tctaacttct tcatcattcc tgacaaataa agctccgatt gcattgagga
    45121 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    45181 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag
    45241 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    45301 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    45361 tgatgggcgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    45421 ctttccattt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    45481 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    45541 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    45601 cgttagttac ggaaatcaat ccaaagggta caagagctgt ccatagtccc cagtctacaa
    45661 atttatggag gcgtgagttg agataaccag atgcaatcgc aatcccaacg accaaagcaa
    45721 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    45781 aaactacctt tctttttttc aaatattctc ccattttttt caaatattct cacaccaaat
    45841 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    45901 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    45961 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    46021 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    46081 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    46141 gttattgatt tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt
    46201 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    46261 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    46321 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    46381 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    46441 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    46501 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    46561 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    46621 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    46681 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    46741 gatgctcggc agataggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    46801 acagggcgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    46861 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc
    46921 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    46981 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    47041 ggaattagtc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    47101 caagaggatt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    47161 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    47221 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    47281 attttggagt ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat
    47341 gtggcagctg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    47401 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    47461 cagaaagagg gctgcgaccg ggagttagac gactggttga aaagtggtaa cgattgacat
    47521 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    47581 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    47641 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    47701 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    47761 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    47821 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    47881 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    47941 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    48001 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    48061 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    48121 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    48181 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    48241 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    48301 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    48361 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    48421 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    48481 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    48541 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    48601 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    48661 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    48721 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    48781 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    48841 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    48901 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    48961 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    49021 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    49081 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    49141 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    49201 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    49261 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    49321 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    49381 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    49441 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    49501 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    49561 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    49621 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    49681 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg
    49741 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    49801 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    49861 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    49921 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    49981 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    50041 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    50101 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    50161 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    50221 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    50281 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    50341 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    50401 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    50461 tttggcattt ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    50521 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg atatattggt
    50581 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    50641 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    50701 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    50761 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    50821 gcagcaacta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    50881 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    50941 ggtcaaggaa ataattcgta aatatgctct tgtctttatt caaaaaggct taaatgtcaa
    51001 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    51061 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    51121 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    51181 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    51241 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    51301 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    51361 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    51421 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    51481 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    51541 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact
    51601 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    51661 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    51721 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    51781 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    51841 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    51901 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    51961 ctgcttcacc ttcggcttca aagtagttca cgcccatttc atcaagagct gcacgaagca
    52021 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    52081 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    52141 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    52201 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    52261 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    52321 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    52381 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    52441 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    52501 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    52561 agaatggcaa accttgtccc acttcttgtg aaattataaa gaggtcaagc tctttaccaa
    52621 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    52681 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    52741 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    52801 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    52861 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    52921 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    52981 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    53041 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    53101 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    53161 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    53221 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    53281 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    53341 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    53401 ttttatcagc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    53461 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    53521 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    53581 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt
    53641 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    53701 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    53761 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    53821 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    53881 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    53941 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    54001 ttttgtgaaa gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa
    54061 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    54121 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    54181 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    54241 agattgttta tatagtgtaa gggggtcaga aacaactagc aagaacaact cataaagtgg
    54301 ccaataaaag aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat
    54361 aatcacctcg ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg
    54421 tttaaaacaa gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatgg
    54481 ttagttttct tggtagaaat attttgataa taattaagca agactattga cattgattat
    54541 taagagtgtc acaattgttg taactaaaac aattacaaca agagaggtat aaaaaatgaa
    54601 actagcagtt attgcagcaa atggacaagc ggggaaggca attgttgaag aagcagtcaa
    54661 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat
    54721 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    54781 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    54841 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gatcaggaag
    54901 cttttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    54961 atttaagcca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    55021 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    55081 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    55141 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    55201 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    55261 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    55321 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    55381 gagaaaaaaa atgaaatcat cgcacaatat gcacgtcacg aaggtgatac aggttcagta
    55441 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaatgaaca catcaaacaa
    55501 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    55561 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    55621 ggacttcgtc gctaattcaa gatacaaagg ctgtcaaaag cacaaagcaa aaataggaaa
    55681 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    55741 tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagct tttttgcgtt
    55801 gtcaccttac ctcgatatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    55861 taaaataaac cagcttttct cccttcgggg agattttttt ttgtttcact gaaagtttcg
    55921 tacgatcttc gcctcgtcgc ctagtctata aacgatttat ccagcaagaa tcatgatgct
    55981 aagggcgtca aaaatccgta tgaaaatagg gaaatggcac agtgttcgat gaacgcaagg
    56041 agtttcatct ttttcactag gattttagtc cgggctcaaa tcagctctct gacttcagag
    56101 ggctttttta ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaatggt
    56161 atcagctaat tacaccataa aggtgcgcag ttactcggct tttcaagccg agtagctgta
    56221 tgcaagcccc ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac
    56281 atggaagtag tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag
    56341 taaaatgctt tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg
    56401 ctctcctaaa atctgctgat ttattactga ctaatacagg aggttttttt atgggacaga
    56461 caatcatatc tgctattggt gtttatattt ccaccagtat cgattattta attattttaa
    56521 ttattttatt tgcacaacta tcacagaata aacagaaatg gcatatttat gcggggcaat
    56581 atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc gttaatttcg
    56641 tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta gggattcgct
    56701 ttgcaattct tggagaagat gcggaagaag aagaggaaga aattattgaa agattggaac
    56761 aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg tctggcggag
    56821 ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag accctcgtgg
    56881 ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg gtgttatcct
    56941 ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg cccttagtat
    57001 tcattctact tggactatac atcatgtatg aaaatggcac gatagagact tttctgatcg
    57061 tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc tctgattttc
    57121 agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt gtagagtggc
    57181 ttttgatttg attaggagat tcttataaat atagtaaaat gaaacaaaaa caggacaaat
    57241 cgatcgtgac agtcaaatcg atttctaaaa atgttttaag aagtagaggt gtactattct
    57301 agtttcaatt tgatatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta
    57361 tgcaagttct tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat
    57421 gatggttagg atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca
    57481 gagtggattt ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa
    57541 ttctgtttga atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc
    57601 tgagatatcg attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt
    57661 caaagtcatg ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat
    57721 cagtgctgcg ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag
    57781 agagcggtca ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt
    57841 ttcacggtcg atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt
    57901 aaagagttct ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata
    57961 aacaggatcc caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg
    58021 aattttatca gtattatgat agtgagcatt gccattgatg gaccataaga gcaatacaac
    58081 taatccacgc aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt
    58141 ataccttatc aaaggagggc tggcaaactt ttcccttgac tagatgcata tttgggatga
    58201 aattagaatt ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg
    58261 ggattaaccc aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc
    58321 gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac
    58381 gctttgaact ttgccattgc tttggccctt gcctttgtgc aggcttggag caatctggtc
    58441 ttctttgctg ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa
    58501 cacatggtgg acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt
    58561 caggaagttg ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca
    58621 ggagagcaga ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc
    58681 atgttaacgg gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga
    58741 agtttcctag ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat
    58801 gctgccaaac tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa
    58861 tcgctggaca agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc
    58921 ttgctggaag ccttgctttt aaaaggcctg cctctcaagt catccgttgt aaactcgtcg
    58981 acagctcttt tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg
    59041 actgcagtga ttaagttggg cttgaaaaag gtcttggtgc aggagatgta ctctgttgag
    59101 accttggcgc gcgtggatat gctctgtctg gacaagacgg gcaccatcac ccaaggaaag
    59161 atgcaggtgg aggctgttct tccactgacg gaaacttacg gtgaagaggc tattgccagc
    59221 atcttgacta gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc
    59281 cagcgttttg tgggagatgt tgcttatcct atgatttcca atcttccctt ctcgagcgac
    59341 cgcaagtggg gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag
    59401 atgttgctgg attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc
    59461 ttggtcttag ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat
    59521 attcaggctc tagccttgct ggaaatcttg gatcctattc gagagggagc ggcagagacg
    59581 ctgaactatc tccgttctca ggaagtgggg ctcaagatta tctctggtga caatccagtt
    59641 acggtatcca gcattgccca gaaggctggt tttgcggact atcacagcta tgtcgattgt
    59701 tcaaaaatca cggatgagga attgattgct ctggcggagg agacagcgat tttcggacgt
    59761 gtttcccctc atcaaaagaa actcattatc caaacgctga aaaaagcggg tcatacaaca
    59821 gctatgactg gggatggagt taatgatatc ctggctcttc gtgaggcgga ttgttctatc
    59881 gtaatggcgg agggagaccc ggcaacccgt cagattgcca acctggttct cttgaactca
    59941 gactttaatg atgttcctga gattcttttt gaaggtcgtc gtgtggtcaa taacattgcc
    60001 cacatcgctc cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt
    60061 attgccagtg ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc
    60121 cagattacca tgattgacca gtttgtggaa ggtttcccac catttgttct gacttttgag
    60181 cgaaatatca aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca
    60241 agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa tctttggaac gagtcaaggt
    60301 tggtctgagt tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta
    60361 tccgtattta gagcctgcat gccattcact ctatggcgag tcctcttgat tgtctggtca
    60421 gtaggaggct tcctagccac agctctcttc ccaagaatcc aaaaactgct tgaaatttca
    60481 accttgacag aacaaacgtt gcctgtttat ggtgtcatga tgttggtctt tacagtgatt
    60541 ttcatcctga ctagtcgcta tcaagctaga aaataaagaa agactgcaat ctgtggattg
    60601 cagtttttta tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat
    60661 ctatcggtga acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat
    60721 atctgtagtt agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa
    60781 ttttaactct cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa
    60841 gatgcaatct attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt
    60901 tcttatcaaa tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa
    60961 ggtaaaatga ttttggtata gtgaggttct gttctatttg atatcatatt tttgataaaa
    61021 acaaaaatgt ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata
    61081 atggaatcat aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg
    61141 ctccttttgc gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat
    61201 tgctctgata aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa
    61261 gcattcattt tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg
    61321 gacgttgatg ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta
    61381 gaacgtctct tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc
    61441 tacgtaagcg agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt
    61501 tatgggttag atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa
    61561 attcgttcag ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt
    61621 acacagaata aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg
    61681 attacacttg agagagaatt gggggtaaac attccctatc catataatat aaatattttc
    61741 tctcacctgt atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca
    61801 ccttcaaaac ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa
    61861 gaaattgaac aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa
    61921 tacgttgtat cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag
    61981 cgagttttag atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt
    62041 gaaacgacag atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga
    62101 ttagataata gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct
    62161 aatctagtta aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg
    62221 tccttgagtc tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag
    62281 cgagcacgtc ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt
    62341 ttacgagcac gattagaaaa gcaatttact gaattggata ttattgatgt agttgcttat
    62401 catcaattag atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta
    62461 gctttgcagg aaccagcaag tgtcccgttt gtcctagtta gtgtttttct aaccgagggt
    62521 gataaacaac gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt
    62581 ccttatggat atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat
    62641 cagccttctt gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag
    62701 acagggaagt atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca
    62761 acatcatgtc ttagtgatta ctagattaaa atcacctatc agagaatggt cgaaggatat
    62821 ccagtgtgtt gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat
    62881 taaaacattg atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac
    62941 aaaagaagaa ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga
    63001 tccagacgga tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat
    63061 tggttgagac gggttatgtg tctgatagag accaatttat cgaaggtctg tatcagagag
    63121 aggcagaagg acagaccggt attgggaatt atattgctat tccccatagc aagagttctg
    63181 ctgtggagaa ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca
    63241 ttgatgggaa aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg
    63301 ctagggagca tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg
    63361 ttgccaaatt agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag
    63421 aaaaaatttt ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa
    63481 ttgcccacac ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg
    63541 tgattcatgt tgagactcag gggacaatag gggtagaaaa tgaattgagt caagagcaga
    63601 ttgatgcagc ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct
    63661 ttgagggtaa aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac
    63721 tgattgctaa agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat
    63781 atgttgaaac acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca
    63841 attgtttgtg gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct
    63901 gacgctcttg tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa
    63961 gcccttggtc tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag
    64021 ccagggattg caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt
    64081 atcggtggta tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag
    64141 gtcaaagtac caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc
    64201 tctttggtaa gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc
    64261 aactggttga cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca
    64321 gttattggag ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcg
    64381 tttgtgttga ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg
    64441 aatactgcta caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa
    64501 aatatctata ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc
    64561 aatattgttg aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca
    64621 acaggtatcg gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc
    64681 gtgccatttg gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt
    64741 gctttgttag ccaacattgt agtcacagga cttgtctacg cgattttgaa aaaaccaata
    64801 aaacatacag aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt
    64861 ttgtaagagg gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt
    64921 ggacaaattc aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga
    64981 tattatggat ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt
    65041 tcaaaaaatt agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg
    65101 ggtagatcaa gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa
    65161 tggtcttgct tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt
    65221 ccttaatcct gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt
    65281 aactattatg actgtagatc caggttttgc aggacaacgt tttttgaagt ctaccttgta
    65341 taaaatccaa gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat
    65401 ggatggttct tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta
    65461 tgttataggt cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat
    65521 ctgttctaga gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga
    65581 gaagaaattt attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt
    65641 tcttggcgta gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc
    65701 tgcgccaatg gcttatagct tatttacaaa acaccttaga attacacctg agcagccaaa
    65761 ctggattaac cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc
    65821 tctcttgcat ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca
    65881 atggggatct aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac
    65941 atctggtccg cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt
    66001 tttagctgct aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat
    66061 cgctggagac ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca
    66121 tcaagcttta gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga
    66181 gaccaaagat actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac
    66241 agttctggta gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa
    66301 gttttctggt aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa
    66361 taaaagtggt acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac
    66421 tcgtaagttt ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga
    66481 tttcaagaca aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt
    66541 gtctgattac aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg
    66601 aaaatcccct gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca
    66661 agcaactcgt aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt
    66721 cttaggtgga tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt
    66781 acaagataaa tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat
    66841 gggaacaatc ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt
    66901 ctttgttttc tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc
    66961 tgtaacttat gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga
    67021 accagttgaa catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc
    67081 ggatgcccgt gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac
    67141 tgtcattgtc ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt
    67201 cgctaaagga gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac
    67261 aggatctgag gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa
    67321 agtacgtgtg gtatctatgc cctcaaccga actatttgat gctcaagatg ctacctacaa
    67381 ggaagacatt ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca
    67441 aagttggtac aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc
    67501 gtctgcccca gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc
    67561 tcaagttaag tccctataga aaccaattac aatgaagata cagctgttgt cagactagca
    67621 gatgtagtga tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa
    67681 taatttatct acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt
    67741 tgcgaagtac gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca
    67801 gcatccacag attgacttag gatattgtaa gttttttgaa agctagagag aaggtctcta
    67861 aaattaaaaa acgcatagta taggatgttg aaatgatgaa ctgcccccca aaagttagac
    67921 agaaaaaatc taacttttgg ggtgttttat tatgaaatta agttatgaag ataaagttca
    67981 gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt
    68041 ggatgtttct ggtctaaagt acatggtgaa attaattgac cgttatgg
//
LOCUS       DAVBOM010000002        67910 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBOM010000002 DAVBOM010000000
VERSION     DAVBOM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.002"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            451..636
                     /locus_tag="VQ878_000066"
                     /pseudo
     CDS             451..636
                     /locus_tag="VQ878_000066"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1248..1532
                     /locus_tag="VQ878_000067"
     CDS             1248..1532
                     /locus_tag="VQ878_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094494.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1525..1763
                     /locus_tag="VQ878_000068"
                     /pseudo
     CDS             1525..1763
                     /locus_tag="VQ878_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1859..2077
                     /locus_tag="VQ878_000069"
     CDS             1859..2077
                     /locus_tag="VQ878_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094495.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ878_000070"
     CDS             complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ878_000070"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET3094496.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5168..6229
                     /gene="dinB"
                     /locus_tag="VQ878_000071"
     CDS             5168..6229
                     /gene="dinB"
                     /locus_tag="VQ878_000071"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET3094497.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(6376..7221)
                     /locus_tag="VQ878_000072"
     CDS             complement(6376..7221)
                     /locus_tag="VQ878_000072"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET3094498.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            7477..8345
                     /locus_tag="VQ878_000073"
                     /pseudo
     CDS             7477..8345
                     /locus_tag="VQ878_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8646..10535)
                     /locus_tag="VQ878_000074"
     CDS             complement(8646..10535)
                     /locus_tag="VQ878_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET3094499.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAKLADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            10673..12238
                     /locus_tag="VQ878_000075"
     CDS             10673..12238
                     /locus_tag="VQ878_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3094500.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEITFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            12238..12978
                     /locus_tag="VQ878_000076"
     CDS             12238..12978
                     /locus_tag="VQ878_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3094501.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(13087..13302)
                     /locus_tag="VQ878_000077"
     CDS             complement(13087..13302)
                     /locus_tag="VQ878_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094502.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(14173..15423)
                     /gene="ilvA"
                     /locus_tag="VQ878_000078"
     CDS             complement(14173..15423)
                     /gene="ilvA"
                     /locus_tag="VQ878_000078"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET3094503.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(15473..15829)
                     /locus_tag="VQ878_000079"
     CDS             complement(15473..15829)
                     /locus_tag="VQ878_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3094504.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(16067..16303)
                     /locus_tag="VQ878_000080"
     CDS             complement(16067..16303)
                     /locus_tag="VQ878_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094505.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERADATKSARYIAKWILRNKKH"
     gene            complement(16410..17432)
                     /gene="ilvC"
                     /locus_tag="VQ878_000081"
     CDS             complement(16410..17432)
                     /gene="ilvC"
                     /locus_tag="VQ878_000081"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3094506.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRYSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(17498..17974)
                     /gene="ilvN"
                     /locus_tag="VQ878_000082"
     CDS             complement(17498..17974)
                     /gene="ilvN"
                     /locus_tag="VQ878_000082"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET3094507.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(17967..19667)
                     /locus_tag="VQ878_000083"
     CDS             complement(17967..19667)
                     /locus_tag="VQ878_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET3094508.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(19868..21535)
                     /locus_tag="VQ878_000084"
     CDS             complement(19868..21535)
                     /locus_tag="VQ878_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET3094509.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(21538..21903)
                     /locus_tag="VQ878_000085"
     CDS             complement(21538..21903)
                     /locus_tag="VQ878_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3094510.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(22060..22248)
                     /locus_tag="VQ878_000086"
     CDS             complement(22060..22248)
                     /locus_tag="VQ878_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET3094511.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(22364..22849)
                     /locus_tag="VQ878_000087"
     CDS             complement(22364..22849)
                     /locus_tag="VQ878_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET3094512.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(23118..24662)
                     /locus_tag="VQ878_000088"
     CDS             complement(23118..24662)
                     /locus_tag="VQ878_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET3094513.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIRDAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMESEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            24875..25177
                     /gene="gatC"
                     /locus_tag="VQ878_000089"
     CDS             24875..25177
                     /gene="gatC"
                     /locus_tag="VQ878_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET3094514.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            25177..26643
                     /gene="gatA"
                     /locus_tag="VQ878_000090"
     CDS             25177..26643
                     /gene="gatA"
                     /locus_tag="VQ878_000090"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET3094515.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            26643..28085
                     /gene="gatB"
                     /locus_tag="VQ878_000091"
     CDS             26643..28085
                     /gene="gatB"
                     /locus_tag="VQ878_000091"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET3094516.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDANQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            28209..29252
                     /locus_tag="VQ878_000092"
     CDS             28209..29252
                     /locus_tag="VQ878_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET3094517.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            29630..30190
                     /gene="efp"
                     /locus_tag="VQ878_000093"
     CDS             29630..30190
                     /gene="efp"
                     /locus_tag="VQ878_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET3094518.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            30212..30601
                     /locus_tag="VQ878_000094"
     CDS             30212..30601
                     /locus_tag="VQ878_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3094519.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            30594..31016
                     /gene="nusB"
                     /locus_tag="VQ878_000095"
     CDS             30594..31016
                     /gene="nusB"
                     /locus_tag="VQ878_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET3094520.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(31066..31302)
                     /locus_tag="VQ878_000096"
     CDS             complement(31066..31302)
                     /locus_tag="VQ878_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3094521.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(31315..31788)
                     /locus_tag="VQ878_000097"
     CDS             complement(31315..31788)
                     /locus_tag="VQ878_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094522.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(31806..31991)
                     /gene="briC"
                     /locus_tag="VQ878_000098"
     CDS             complement(31806..31991)
                     /gene="briC"
                     /locus_tag="VQ878_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET3094523.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(32150..32917)
                     /locus_tag="VQ878_000099"
     CDS             complement(32150..32917)
                     /locus_tag="VQ878_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET3094524.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(32914..33780)
                     /locus_tag="VQ878_000100"
     CDS             complement(32914..33780)
                     /locus_tag="VQ878_000100"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET3094525.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(33817..35184)
                     /gene="accC"
                     /locus_tag="VQ878_000101"
     CDS             complement(33817..35184)
                     /gene="accC"
                     /locus_tag="VQ878_000101"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET3094526.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(35196..35618)
                     /gene="fabZ"
                     /locus_tag="VQ878_000102"
     CDS             complement(35196..35618)
                     /gene="fabZ"
                     /locus_tag="VQ878_000102"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET3094527.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(35615..36100)
                     /locus_tag="VQ878_000103"
     CDS             complement(35615..36100)
                     /locus_tag="VQ878_000103"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET3094528.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPNPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(36103..37338)
                     /gene="fabF"
                     /locus_tag="VQ878_000104"
     CDS             complement(36103..37338)
                     /gene="fabF"
                     /locus_tag="VQ878_000104"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET3094529.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(37360..38091)
                     /gene="fabG"
                     /locus_tag="VQ878_000105"
     CDS             complement(37360..38091)
                     /gene="fabG"
                     /locus_tag="VQ878_000105"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET3094530.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(38125..39045)
                     /gene="fabD"
                     /locus_tag="VQ878_000106"
     CDS             complement(38125..39045)
                     /gene="fabD"
                     /locus_tag="VQ878_000106"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET3094531.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(39038..40012)
                     /gene="fabK"
                     /locus_tag="VQ878_000107"
     CDS             complement(39038..40012)
                     /gene="fabK"
                     /locus_tag="VQ878_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET3094532.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(40131..40355)
                     /locus_tag="VQ878_000108"
     CDS             complement(40131..40355)
                     /locus_tag="VQ878_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3094533.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(40415..41389)
                     /locus_tag="VQ878_000109"
     CDS             complement(40415..41389)
                     /locus_tag="VQ878_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET3094534.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(41389..41823)
                     /locus_tag="VQ878_000110"
     CDS             complement(41389..41823)
                     /locus_tag="VQ878_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3094535.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(41917..42702)
                     /locus_tag="VQ878_000111"
     CDS             complement(41917..42702)
                     /locus_tag="VQ878_000111"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET3094536.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            43027..44391
                     /locus_tag="VQ878_000112"
     CDS             43027..44391
                     /locus_tag="VQ878_000112"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET3094537.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            44394..44765
                     /locus_tag="VQ878_000113"
     CDS             44394..44765
                     /locus_tag="VQ878_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET3094538.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIARDKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            44979..46253
                     /gene="serS"
                     /locus_tag="VQ878_000114"
     CDS             44979..46253
                     /gene="serS"
                     /locus_tag="VQ878_000114"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET3094539.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(46278..47177)
                     /locus_tag="VQ878_000115"
     CDS             complement(46278..47177)
                     /locus_tag="VQ878_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET3094540.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(47287..47835)
                     /locus_tag="VQ878_000116"
     CDS             complement(47287..47835)
                     /locus_tag="VQ878_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET3094541.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(48053..49375)
                     /locus_tag="VQ878_000117"
     CDS             complement(48053..49375)
                     /locus_tag="VQ878_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET3094542.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(49466..49554)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(49718..52054)
                     /locus_tag="VQ878_000118"
     CDS             complement(49718..52054)
                     /locus_tag="VQ878_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET3094543.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(52158..52706)
                     /locus_tag="VQ878_000119"
     CDS             complement(52158..52706)
                     /locus_tag="VQ878_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET3094544.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(52703..53005)
                     /gene="zapA"
                     /locus_tag="VQ878_000120"
     CDS             complement(52703..53005)
                     /gene="zapA"
                     /locus_tag="VQ878_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET3094545.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            53092..53964
                     /locus_tag="VQ878_000121"
     CDS             53092..53964
                     /locus_tag="VQ878_000121"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET3094546.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            53976..54590
                     /gene="lepB"
                     /locus_tag="VQ878_000122"
     CDS             53976..54590
                     /gene="lepB"
                     /locus_tag="VQ878_000122"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET3094547.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            54718..57084
                     /locus_tag="VQ878_000123"
     CDS             54718..57084
                     /locus_tag="VQ878_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET3094548.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGFSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(57132..58415)
                     /locus_tag="VQ878_000124"
     CDS             complement(57132..58415)
                     /locus_tag="VQ878_000124"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET3094549.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(58576..58968)
                     /locus_tag="VQ878_000125"
     CDS             complement(58576..58968)
                     /locus_tag="VQ878_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3094550.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(59267..59896)
                     /locus_tag="VQ878_000126"
     CDS             complement(59267..59896)
                     /locus_tag="VQ878_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3094551.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(59941..60180)
                     /locus_tag="VQ878_000127"
     CDS             complement(59941..60180)
                     /locus_tag="VQ878_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094552.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(60330..60596)
                     /locus_tag="VQ878_000128"
                     /pseudo
     CDS             complement(60330..60596)
                     /locus_tag="VQ878_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(60621..60932)
                     /locus_tag="VQ878_000129"
     CDS             complement(60621..60932)
                     /locus_tag="VQ878_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3094553.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(60857..61099)
                     /locus_tag="VQ878_000130"
     CDS             complement(60857..61099)
                     /locus_tag="VQ878_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3094554.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(61100..61732)
                     /locus_tag="VQ878_000131"
     CDS             complement(61100..61732)
                     /locus_tag="VQ878_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3094555.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(61746..62741)
                     /locus_tag="VQ878_000132"
     CDS             complement(61746..62741)
                     /locus_tag="VQ878_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3094556.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(62738..63436)
                     /locus_tag="VQ878_000133"
     CDS             complement(62738..63436)
                     /locus_tag="VQ878_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET3094557.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(63513..64523)
                     /locus_tag="VQ878_000134"
     CDS             complement(63513..64523)
                     /locus_tag="VQ878_000134"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET3094558.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(64507..65514)
                     /locus_tag="VQ878_000135"
     CDS             complement(64507..65514)
                     /locus_tag="VQ878_000135"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET3094559.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(65501..66454)
                     /gene="mvaD"
                     /locus_tag="VQ878_000136"
     CDS             complement(65501..66454)
                     /gene="mvaD"
                     /locus_tag="VQ878_000136"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET3094560.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(66436..67314)
                     /gene="mvk"
                     /locus_tag="VQ878_000137"
     CDS             complement(66436..67314)
                     /gene="mvk"
                     /locus_tag="VQ878_000137"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET3094561.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(67436..67558)
                     /locus_tag="VQ878_000138"
     CDS             complement(67436..67558)
                     /locus_tag="VQ878_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET3094562.1"
                     /translation="MTTGWFQVNGRWYYAYSSGALAVNTIVDGYSVNYNGEWVR"
BASE COUNT        20218 a        15194 c        12696 g        19802 t
ORIGIN      
        1 gaactgacga agtcagtaac atctatacgg taaggcgacg ctgacgtggt ttgaagagat
       61 tttcgaaaag tattagttaa atcttgttta atatctctac accatactat tttacatata
      121 ttatttagcg ccacatagta ctgaactctc tccaaaaacg gttatgcctc tttgaatagg
      181 gcgttatcac aagaaaagca tctccacgtt tcaacttcat atggctcaaa aacaatcaat
      241 tgatgctaaa acctgtacct agatgtttcg gttcataaaa ccatgaaact gtaaaagtgg
      301 atgaaattga tagcgatagt caaatcaaga ggcatcataa ctctaaaaag tcacaatata
      361 taagttcatc ctcggaaaaa tatcattcta attgttgaaa tggatatata aacaggggta
      421 ttaacattaa atgctcatga aacaacgaat acaggtatca aaactatgac aaaacaagtc
      481 cctaaattta ctaaagacac tgctcaactt tacacctgta aatggttgtt gtataataaa
      541 gttacaaaga tgtacgacca cactgttgta aatcatagtg ttcgcgaata tattactgat
      601 agcatttcta caaatacaat tgaagaggct ggataggctt taaacgaaat atgtcagtgt
      661 tttggcattc ctagccttaa tatcatttaa agaattgtat agataaaatt ttttccaata
      721 cagacactcg taacaactgc ttcatttttc taccaacata tttaggaaca ggataagata
      781 caagaggatt aatccataaa tcagttctat accaatctaa gacaaataag ctaaaaaaac
      841 gattgataat aagcaaatag attccaaatt ttctctatct gctcatttta ataaacaata
      901 ctagtgtaac tatccttcca gtcagaaact tgtcaaatca caccgaaaac tcttctaaaa
      961 tttatctcgt taggcaatca agcaaaaact cgacgatagt acaaacatta tcatacagaa
     1021 ttgactgcct aaattatata ctttagtaag gttttcggat aagaaaaaag gttcatttta
     1081 catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg atttaaagca
     1141 acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa ctacattttt
     1201 gaatataaac tacaataata taaactaaat tttataggag gaagacaatg gattggtacg
     1261 attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg tttcgctatt
     1321 tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta gaaaagttgc
     1381 tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc tttcaagagc
     1441 atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta accaatgttc
     1501 aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca agccctaaat
     1561 aagaaattaa ttcaggaaaa tctgacttta acaattatgg ttatgtctta gaatatcatg
     1621 gtttacgtgc cacacaagat gttgatgctt tttatgacca aaatcagaaa atcaatgaaa
     1681 ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca cgaagagtta tggctcaaca
     1741 atcatgttgc aaagcaaata tgaacaaaca acctccctta agtttatgcg aatccttgta
     1801 ctcatttgag aatctgaccg ttttagtagt ccctattgag tatgtgttag gaatgaagat
     1861 gatgagtatc agagagcagg atttgcaaga tattggtgca attattaaat acaaaaactt
     1921 tcattcacca ttcgatacct ttaaatattt aaaagacatg ggatttgata ctattgacct
     1981 ctctgttcta ttagaaggtt ttagttatgc ttatggtatg gattggttag aaaaattttt
     2041 taaagaaaat caagataaac ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc
     2101 aattagccag tcgtcttatt tttatgatga aatgaaatga aataaaatcg gaacaaatca
     2161 cttagagaat tccagtcaat ttctagcact gtttgagccg tttcagcgga ctatagtaaa
     2221 atgaaataag aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta
     2281 gaagtaaagg tgtactattc tagtttcaat ctattatatt tcagattcgg tccactgttc
     2341 cttcccaaaa acattgcata ttgcgccgaa ggaattgctc atactatccc aagcacaaaa
     2401 ccctcagtcg tttgaccgag ggttcctttt tattattcaa gaacttgatt agctcaatgc
     2461 atccaaggcg tcatccattg aaagaacttc gtggaagaca cgttgtgtca attcagtttt
     2521 ttgttctgga gtgaggtatt tagtgtttac acagtatcca gagatacgta cgataacgtc
     2581 ttcgcctgac atgatttttt cgtaaacatc gttcaagtcc ataacgttca agttaacgtg
     2641 ttgtccaccg ttttcgaagt aaccatcaag gattgttacc aagttatcaa cttgttcatc
     2701 acgagtctta ccaagagcgc gaggtgatac ttgtgtagtc aatgagatac cgtcagctgc
     2761 ataactaaag tcaaggctag aaagtgagtt caagttttgc aaccaaccac ctttagcttt
     2821 gttagatggg ttagcacctg gtgagaagaa ttcaagttta gacaagttca cagaaccatc
     2881 ttcgttgagg tatacacctt tgtgaactgg tgagttacca gtttgtttag agtaagcaac
     2941 gttagatgtg attgtcaaaa gtgatactgt agcttctgcg tctttgtata gtttgtggct
     3001 acgtagacga gttgtgtaag cttcgatcaa ccattctgcc aattcgtttg aacgtgggtc
     3061 atcttcaccc cagcgtgggt agtcaccgat tgtttcgtaa tcgtagatgt agccatcttc
     3121 gtcacggatt ggtttaactg tagcgtattt gatagctgac aatgtatcaa cagtgttagc
     3181 aaatccacag ataccgaatc ccatgttggc acgttgttta gttggcaaga aggccatttg
     3241 aacagcttcg tagttgtacc tatcagtcat gtagtggatg atgttcaagg catctacgta
     3301 agtgtcagtc aaccagtcaa gagatttttc aaagttcgct ttaactgatt cgaattcaag
     3361 aacttcgtca cgaataggat cgatgtcaaa tactttgtag tctttgtgaa catcgtcgta
     3421 accaccattc aaaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtactg
     3481 gatgttgtgg cgttgttctt cattttctgg atcaagtgga gacacacagc atgagataca
     3541 gctcatttca ccatatccgt ctttagccat tgttgttaca ccttcgtatt ggatagaaga
     3601 gtgtttgtgg ctcatgtgca tacagtagcg acggaagttg tatggcaatt tgtcagtcca
     3661 aagaactgtc aagtttggtt ctggtgagtt accgatgttg tcaagagtgt tcaagaaacg
     3721 gtagtccatc ttagtaacac ggtgacgacc gtcgttaccc ataccagcca tagaagttgt
     3781 gataaaggtt gggtcacctg agtacaattg gtcataagct tttgtacgag caaatttaac
     3841 tgtacgaagt ttcataacga aatcatcaac gaattcttgg atttctgatt cagtaaatgt
     3901 accacgagca aggtcacgtt ctgcaaagat gtccaatacg attggtacac gacctagaga
     3961 tgtagcagca ccgttaatca cacggcagac agccatgaaa gcaatgttaa cccattggat
     4021 tgcttctttc acgttcatcg ctggtttgcg aacatcaacc ccgtaaaggt cacccaggcg
     4081 aacaacttgt tgcaatgctt ggtattgaag gtttacttct tcacgaagac ggattgtttc
     4141 ttcatcgatt tctttgattg cattccagtc gtttactttt tcttgcatca agtagtctgc
     4201 accgtaaaga gcaagacgtg cgtaaacacc gatgatacgt ccgcgtgagt atgcatctgg
     4261 aagaccagtt acagtgtgtg catgacgagc gcgacgaata tttgaagtgt aggcacggaa
     4321 aataccgtcg ttaactgttg ttacatattt agtgaagatt tcgtgaacag ctgggtctgg
     4381 ttcgtatcca ttttctttta aagtagtttc agccatacgg ataccacctt ttggcatgaa
     4441 gttcaatttg aagagttcat cattttggat accaaagata acttcatttt ctttgtcgat
     4501 aaatccagca gggatatcag cgatagatgt tggacgagtg tccattggga aacgagtttc
     4561 ttcgtagtgt gctttagttt cttctacaat tttcttgatg tgaagtgaac gctctgttgg
     4621 tcctgcaagg aagctttcgt ctccatcata aggtgtgtag ttagcttgta caaagcgtga
     4681 tacacttgct ttttctttcc aatctacgcc tttgaagcct tcccaagctt tgtcaaaaat
     4741 atcttgtgct tcaacaaccg tcttaacaac catattaatg tcctcttttt tctagtaaca
     4801 gtcatctgtt acattcataa gacaagtata ccataaagta atcgatttca acaagtgcaa
     4861 aatccctatt tttacacttt cttttctaaa acagtctata ttttatttca aactgtatta
     4921 tatttttgaa aaaaataaag tccttttttc tttttttcag aaaaaagggt ataataaaag
     4981 aaaataagca gtaacactca atggaaatcg aaaagcaaac taggaagcta gccgcaggct
     5041 gctcaaagca ctgctttgag gttgtaaata gaactgacga agtcagctca aaatactgtt
     5101 ttgaggttgc agatggaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaaaggt
     5161 gctaggcatg ttgatttttc ctttgttaaa tgatttgtca agaaaaatca tccatattga
     5221 catggatgcc ttttttgctg cggtggaaat caaggataat cctaaactca gaggaaaacc
     5281 tgtcattatt ggaagcgacc ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag
     5341 ctatgaggct cgagcttttg gtgtccattc tgccatgagt tccaaggaag cttatgaacg
     5401 ttgtccccag gccgtcttta tctcaggaaa ttatgagaaa tacaaagctg tgggactcca
     5461 gattcgagct atttttaagc gctatacaga tttgattgaa cccatgagca ttgacgaagc
     5521 ctatttggat gtgacagaaa ataaactcgg tatcaagtca gcggtcaaaa ttgctcgcct
     5581 cattcaaaaa gatatctggc aagaactcca tctaactgct tctgccggta tttcctacaa
     5641 caagttctta gctaaaatgg cgagtgatta tcaaaaacct catggtttga cagtgattct
     5701 acctgaacag gctgagaatt ttctcaaaca aatggatatt tccaaatttc atggagtagg
     5761 aaaaaagaca gtagaacgtc ttcatcaaat gggcgttttt actggtgctg atttacttga
     5821 agttcctgag gtgaccctaa tagaccgttt tggtagacta ggctatgatc tgtatcgaaa
     5881 ggctcgtggc attcacaact ctccagtcaa atccaatcgc atccgtaaat caatcggcaa
     5941 ggagaaaacc tacgggaaga ttctccgtgc tgaggaagat atcaaaaaag agctgactct
     6001 tctatcagaa aaagtcgctc tcaatctaca tcaacaagaa aaagctggaa aaattgtcat
     6061 tttgaaaatc cgctacgagg acttttcaac tcttaccaaa cgaaaaagtc ttgctcaaaa
     6121 aacacaagat gctagtcaga taagccaaat agccctgcaa ctctatgaag aattaagcga
     6181 gaaagaaaga ggtgtccgcc tattggggat taccctgact ggattttaaa gctcaatgaa
     6241 aatcaaagag caaactagga agctagccgc aggctgctca aaacactgtt ttgaggttgc
     6301 agataaagct gacgcggttt gaagagattt tctaagagta taaaaccttg aagagttgcc
     6361 ccttcaaggt ttttcttata caaataaacg gacaaaactg taaagtagca aaacactacc
     6421 aagcacgata cggtatttac caaaaagggt gaagtcgtgt tttttcacat agctggtcaa
     6481 gaagcgaata gccaccatgc tgaccgcaaa agctactccc atcgcgacca agagcaaaaa
     6541 caattgccca aagctcaaga gttctccggc tttcacaaat ttgaaaatct ttaaggcact
     6601 agctccaaac ataacgggaa tcccaagata gaaggtaaat tctgtcacaa ctgaacgact
     6661 ggttccattt aacaaaccac cgacaatcgt tgcacctgaa cggctagtcc ctggtaaaag
     6721 agcaagaact tggaagagtc cgatatagaa agcggtcgta taaggaagct tgtccaactc
     6781 tgttacactt ggctcgatag cacgcgcttt attgcgcttt tccaaataga tgaaggcaac
     6841 cccgtagata atcaacatga gagcaactga aaccatgtta tggaagtggg tatcaaacca
     6901 atcatcaaat ttaaagacac caagtaaagg caaagtggca atcaagacct tcaaccatag
     6961 tctccaagtc ttacgaactt cctgtttgtc cttagtcggt ttaaaaggat tgagcttgtt
     7021 aaaataaatc accataactg ctaaaatagc accaagctga atcacgacat taaacatgga
     7081 cataaaggct tcattttgat tttggtattg gataaactcc tctgctaaaa tcaagtgacc
     7141 tgtactggaa atcggcaacc attccgtaat tccttcaaca atcccgaaga agatagattt
     7201 taaaatttca ataagataca tatatttctc cttatattat atttaacgca gttagctact
     7261 gccaaagccc aagtggtata cttggaataa gccactgtgg attagttcat ttcctccaat
     7321 cgcttgacga tttccgaaag ggtctaacaa cagctttttg tttcaattgg taatgagttt
     7381 gataacgcat agacgtttta tctcgtctaa ggtaacaagg caaaaagttc gtggataacc
     7441 aagtagactt gaaatactat atctggaggt actcccatgc tttatgtggg cattgatgtc
     7501 gctaaaaata aacacgatgt tacagccttg aatgttcgag gaaaactgtt cttaaaccac
     7561 tcactttttc aaataataaa gctggttttg aactcttaga tctgtctttt cgacagctca
     7621 accaagactg tctcatcgct cttaaacttc tttctgaccc caatcgtgaa caatttcaac
     7681 acgataatcg gcaagtagaa ctaaaaatac tggctagaca tattcatcgt ctcaagaaaa
     7741 aacagtctga ttggaaagta caatacactc gttgtcttga tatcatcttt cctgagttgg
     7801 ataaaatcgt tggaaagcat tcagaatata cctaccaact cttgacacgc taccctaatc
     7861 ctcagaaaag gcttgaggca agatttgata agctgataga aattaagcga ttgaccgctt
     7921 ctaaaattca ggatatcctc tcagtcgcac ctcgttctat cggaacaaca tctcctgctc
     7981 gtgaattcga aatcatcgaa atcatcaaac attacaagag gctcattgac aaggcggaaa
     8041 catgtgtcaa tgacttgatg gctgagttca actcggtcat cacgacggtt actgggattg
     8101 ggggtcgttt aggggcggtc attttagccg agattcgaaa tattcatgcc tttgataatc
     8161 ctgctcaatt acaagctttc gctggactgg attcttctat ttatcagtca ggtcagattg
     8221 atttagctgg aagaatgatc aaacggggtt cccctcatct gcggtgggca ctcatacaag
     8281 ctgccaaagc atgcgctcgc ttttcacctg cttttaaggc ctatcttaag actaagttag
     8341 aataaggaaa acattacaat gtagccatca tccaccttgc aaaaaaactt atccgaaccc
     8401 tgttttatat cctaaaaaag agctgccatt tgacgaacaa aaagtgatgt aatttctgaa
     8461 attaacacag gattaccttt gaaaaaatgg actttttcaa gggctttttg ccgtgctcta
     8521 aaatcatcgc caaatcatca aattgaaata agaaatagtt tagataaaac tattgacttt
     8581 tcttatagtt tgtctttctt ctatcttcca ttatatcata ctttttcagt ctatggtagc
     8641 tctctttaaa aggctccgat actgccgcca cctccgcctc cagagaagcc accgccagaa
     8701 cttccacttc cagaagatac ggagtaggta cttgctgtat ttgcgacact agcataatgg
     8761 ctcatttgcg cgcttgaatg ataaaacata ctgtgccagc cataagctac atagagattg
     8821 atatctggat tttcaacttg aatctgatga accttcatca aatgactaac cttgtccgca
     8881 tagccaaata aggttgcata gaccaagaga cgattccaaa caacaatact ttccaattca
     8941 gccttatcca gtcgtgcaat ctcacgtaac atattttcaa aactggtcca gagatagtag
     9001 acctcagctc ccgcttcatt tagaacacca tcacgattat ctagtcgaag cttccaataa
     9061 tagaaaacag acaaaactaa ccctagaaaa ccaagtattg gcaaagggag gtaaagatag
     9121 ccatgaacgt ctaaactgta caagaacaaa ccaaatccga taaatagggg caagatagtc
     9181 aagacaccca tacccacttg caaagccttt tccaaaccag ttaaaggacg atagtaatct
     9241 gggagccccc agaaggaaac tcgttttctc actccttctt gcatctggtt caatacctct
     9301 tcaaaagaag atttgagttg aagccctctt gcttgaatcc gtttttcatc agaaactttg
     9361 gctctacgat aaagactatc agataccttg taatccgcaa acaaattgga aagagtttct
     9421 tcttttttac ctgaaaaagc tagatttagg cagtctttct caaagcttga caaaccatct
     9481 tcttttacta gcctcaaacc aactgcatct ccttctgaaa tgatagagac attcccacgg
     9541 tctatcacat ctagcaaggt agcttgaata agttgatcaa aggtgaattt tccagctccc
     9601 ttgaccaagg gactcacttc ctccaaggag gtcgagtaga ctgcttctga taaaaccata
     9661 ggctctaatt ccattggggg ttcatagaga cgatgatttt tagcatattt gattgaagga
     9721 gcggtctttc ttctatagat aaaatagaaa cagatgctca ataacaagga gatggaaagg
     9781 atcgaaggga agatccaagt aagtagttgt ttactttgat ctttttcttt aacgatcgaa
     9841 tcctctatct tattaaactc ttctaaacga ttccctttca agccctgatc cctagcgcta
     9901 gcaaaatcag ttcgcggcca gtaggcatgc aattcaactc cacgcttagc cggaagattg
     9961 tctaaacgaa tagtataatc aaggttactc ttttcaaccg ttctctctct aaaaagtttc
    10021 cctgtatgga aaaagagttt ctcagccccc ttgtctcccc ttacatgaaa ttcaaacttt
    10081 tcaatagact ctgaactatc tgtcagaggt tgccaattta attcagcgat atcatcataa
    10141 aggaaaagta aattttttaa gttccagacg aggtcaactt caactatgtc gccctcctga
    10201 cctggattat agactctcac agtataacca tccgcttctt ctgttacttc gctagtcaca
    10261 tctgctagtt ttgcaccgtt tttcgcggcc tgaatctttg gatgagggtc aatgtcaaac
    10321 ccgctaggca tcttaccagc acgtccaagt cccacgattt ggcccttaaa gtcctcctca
    10381 aactggtaaa ctatcttctg tctaaactct gccgtattgt ctgcatgaat atacaaatcc
    10441 ccttgataag agtttatctt gaaatcaatg gcaaaaacag agagtggaag aaggcaaaac
    10501 aagcctaaca ccagtaagaa aaaagttttt ttcatcaact aagccccctt tttatctttc
    10561 ttatcattat agcatttttt cgtaagtaaa ggcttactta tgttgaaaaa ttacgcattt
    10621 ttcgataaaa taggagacag ttatttttta atagatcaga ataggagaaa tcatgagaaa
    10681 aatatactta tctattttca caagtctctt gctgatgcta ggacttgtca atgttgctca
    10741 agccgatgaa tatttacgca tcggtatgga agcagcatat gctcccttta actggaccca
    10801 ggatgatgat agcaacggag ctgtcaaaat cgatgggacc aatcagtatg ccaacggata
    10861 cgatgttcaa atcgccaaga aaatcgctaa ggacttaggt aaagaacctt tggttgttaa
    10921 aaccaagtgg gaaggtctag tccctgccct tacttctggt aagattgaca tgattatcgc
    10981 aggtatgagt ccaactgcag aacgcaaaca agaaattacc ttttcgagca gttactatac
    11041 tagcgaacca gttttgcttg tcaaaaaaga ttctgcctac gcaagtgcta aatctttgga
    11101 tgactttaac ggtgcaaaaa tcacttctca acaaggggtc tacctttata acttgattgc
    11161 acaaatccca ggtgctaaaa aagaaacagc catgggagac ttcgctcaaa tgcgacaagc
    11221 tcttgaggct ggtgtcattg atgcttatgt ttctgaacgt ccagaagcac tgactgctga
    11281 agctgcgaac tctaagttca agatgattca agtagaacct ggtttcaaaa ctggggaaga
    11341 agatacagct atcgctattg ggcttcgtaa aaatgacaat cgtattagcc aaatcaatgc
    11401 cagcattgaa accatttcaa aagatgacca agttgccttg atggatcgta tgatcaagga
    11461 acaacctgcc gaagctacaa caactgaaga gactagcagt agtttcttta gccaagttgc
    11521 taaaattctt tctgaaaact ggcaacaact cttgcgtggt gctggtatca ctcttttaat
    11581 ctctatcgtc ggaaccatca taggtctcat tattggactt gccattggtg tcttccgtac
    11641 tgctcctctc tctgaaaaca aagtcattta cggcctacaa aaactagtcg gctgggttct
    11701 caatgtctac attgaaattt tccgtggtac gccaatgatt gttcaatcga tggttatcta
    11761 ctatggaact gcccaagctt tcgggatcaa ccttgaccgt acactggctg ctatcttcat
    11821 cgtttcaatc aataccggtg cctacatgac tgaaatcgtc cgtggtggta tcctagcagt
    11881 tgacaaggga caatttgaag ctgcgactgc tcttggtatg acccataacc agaccatgcg
    11941 taagattgtc ctacctcagg tagtccgtaa catcctacct gcaactggta atgaatttgt
    12001 catcaatatc aaagatacat ctgtattgaa cgttatctct gttgtcgaac tttatttctc
    12061 aggaaatacc gtggcaacac aaacctatca atacttccag acatttacaa tcatcgccgt
    12121 gatttacttt gtcctcacct tcaccgtaac acgtatccta cgctttatcg agcgcagaat
    12181 ggacatggat acctacacta caggtgctaa ccaaatgcaa acggaggatt tgaaataatg
    12241 acacaagcaa tccttgaaat taaacacctc aaaaaatcct atggacaaaa cgaagtgcta
    12301 aaagacattt cactcactgt ccacaaggga gaggtcatct ctatcatcgg aagctctgga
    12361 agcggaaaat cgaccttcct acgctccatt aacctacttg aaacaccaac tgatggacaa
    12421 atcctttatc atggacaaaa cgtcctcgaa aaaggctatg acctcacgca ataccgtgaa
    12481 aagttgggga tggttttcca atcctttaac ctctttgaaa atctcaatgt tcttgaaaac
    12541 acaatcgtcg ctcagacaac tgtcctaaaa cgcgaacgca cagaagctga aaagattgcc
    12601 aaagaaaacc tggaaaaggt cggcatggga gaacgctact ggcaagccaa accaaaacaa
    12661 ctctcaggtg gtcaaaaaca acgtgtggcc atcgctcgtg ccctctccat gaatccggac
    12721 gctattctct ttgatgaacc aacatcagct ctcgatccag aaatggttgg agaagtcctc
    12781 aaaatcatgc aggacctggc tcaggaaggc ttgaccatga ttgtcgtaac ccatgaaatg
    12841 gaatttgccc gtgatgtctc tcaccgtgtt atctttatgg ataagggcgt gatcgctgaa
    12901 gaaggtaaac cagaagacct cttcaccaat cctaaagaag accgaacaaa agagttcctt
    12961 caacgctatc tcaaataaaa agaaaaggct gcatcaaccg tgcagtcttt ttgctgtcct
    13021 caaaatgaaa aggcagattc tctatctcta ctacttgaag gtcaagaatc cgccgttatc
    13081 caaagattaa tcttcaaatt tttcataatt tttttcatag aaatcaatta ggcctagggc
    13141 tgtttcaaat gaaatatttt ttacttttgc acgaccctgc gccagagcaa tgatagacat
    13201 ttcacgcgca ttcgtttctt tagagatacg gtagcctgtg attttcttat cacgaaccca
    13261 gccaacaact gattctactt tttcaaagtt tgacttagcc atgtttttct cctattttct
    13321 tctttataat atttaattgt atacgttttt actacttttg tcaataaaaa aaacatatat
    13381 tcaacgaaaa taattagttc agaattttct tacttccttt ttaaatccga taatatatag
    13441 gttttgctag cctctacacc ataaatattt gctaataaaa atactgtatt attaccctct
    13501 taaggtgcga aattattcaa gttcttaaaa aatgcttctc tatttccgta agatagctta
    13561 tttcttcgat ttaagaactg aagatgatag ttctaacctt tagaaatcca agccttcact
    13621 agctcaaaaa ctcctatctt tcttcctcaa taaatcatct gagagatagg tattccttat
    13681 gtccttaaaa ttcatcactc ctttggatat tgaggtgcta gcctagaagc agacacccga
    13741 ttatctaaac catccttaat agagatgaca agacagataa gctcagttaa ttacttatat
    13801 atctttttaa tatggtatat ttgtcaacaa aaagaaatca aatcatacct tatactcaat
    13861 gaaaatcaaa gagcaaacta ggaagctagc cgcaagttgc tcaaaacact gttttgaggt
    13921 tgcagataga gctaacgtgg tttgaagaga ttttcgaaga gtattaaaga cagtgtgact
    13981 atgcttgtca atagatagga aatcaaaatg aaggatggaa atctgagcca aacatcataa
    14041 gtgctataat gaacagaagt aagaattgca cgataagttt tctaaaacca taggaatcgt
    14101 cccctttctt catcttcatt atagcacata tacatcagtt gtacaaataa tatgatattt
    14161 ttttattagt cctcagacaa gcatattata aagcgtttca ttaccattta agttaatata
    14221 agctggatca aaaccttcca ttctacgaat caaacctgca taatcatgct tatctgctaa
    14281 agcgatccca attaatactg ggcctgttcc cttgctagct cgtttgatat actcaaaacg
    14341 tgtgatatca tcatttggcc ccaggatatc atttacaaac tcacgcaaag ctcctggacg
    14401 ttgtgggaaa ttgaccacaa agtaatgttt gataccatca taaatcaagg cacgctcttc
    14461 catttctggc atacggttga tatcattatt tcctccagaa atgatacaac aaatggtttt
    14521 ccccttaata tattcagcta aaacctctaa agaggcgata ctagccgctc cagcaggttc
    14581 tgcgactatc ccttgcttag agtaaaggtc aatcaaggtt tcagaaatca atccctcatc
    14641 gacacctacc aaagttttaa tatgttgacg agttgcttca taggtcaact gacctacctt
    14701 ttgcacagca atcccatcag caaatttatc aatttccttg agtttgactg gacctccagc
    14761 ctcaaaggca gctttcatgg aacgcgctcc attcgcctct actccgataa cctcaatctc
    14821 tggacttgtt tccttgatat aggtagaaac cccggcaatg agaccgccac caccaacagg
    14881 aaccaagaca gcatcaaaat caatcgattc ttttcgagct tcttctaaaa tctcataagc
    14941 aactgttcct tgacctgctt gaacatgagc atcatcaaaa ggatcaataa aggtacgatt
    15001 ttcagagact gtaaattctt gagctgcttt ggctgaggca tcaaaggtat ctccaactag
    15061 tttaatagtt acaaaatccc caccaaaaaa gcgaacctga ccaatctttt gttgtggcgt
    15121 agtaatgggc ataaagatag tagcaggaat tttcatttca ttacaagtat aggctactcc
    15181 ctgcgcatga tttcccgcag aagcgcagac taccccacgt tcacgttctt ccttgctgag
    15241 ctgggaaatg gcataatagg caccacgaat tttaaaggag cgaacacgct gggcattttc
    15301 ttttttcaaa taaatcttag caccatactt ctccgataaa taatgatcgt aatccagtgg
    15361 agtattcaca accacaccgt tcaagacctt gtgagccttg attatatctt ttgaacttaa
    15421 catataaaac ctctttttct ataaaaaaca gtcactaatg actgtttttt agttattcat
    15481 ctccgaaaac ttcagtaaca ctttcatggt atttatgagc catacgaatc gaaaactctt
    15541 taggaagttc ataacgattt gtggaaatcc aatcatataa ccattctacc aaactttctt
    15601 cactatcatt acgatggaag ataaaatagt ttaaaatttc tttatattct acatcattca
    15661 aatccaacgt gtctacaaat tgactacgag gaacaaaatt agaatctaat tttcttagtt
    15721 gatctgtcaa ttctcccaat tgtaaatcca actgaaaaaa tagtttttgc agttgcctat
    15781 cagtttcatc acatcctgtc ttgatagaaa acaaattggt aatattcata tgatttcaac
    15841 ccctaaataa gtacatctaa tatcccacga atagctgaag ctaaagtttt cgcagtccag
    15901 tcatttaaac ccgattcttt caatccagat gcaataattt gctctatttg atataaatcg
    15961 ccatctatcg tctcatttat tctgcgaaga ggaccttcaa tataggataa agcttctccg
    16021 aatctaacag ctgatttagg tcctaatgat ttaccaacta tatttgttaa tgttttttat
    16081 ttctcaaaat ccatttcgct atataacgag cagatttagt cgcatcagct ctctcaaacg
    16141 gagaatgaat ttcaagacct tcttctctag ctatttgtgc caatttgaag aattgttcaa
    16201 aggtcatatg caacctacca tcttcaaaat tagcatcatc ataaatgtta attacagcat
    16261 tttcatcata cgaccaatct gctttatttt ggtctgctag cactattacc gacggtgtaa
    16321 ttacattata caactagaac caataataac gatgcaattt ttctcataat ctttttcata
    16381 aaatcatctc cagcgctata tatttctaat tagttataga ttttgaatgc atcatcgtcg
    16441 tttttaccaa cgaatggcat tgctttacgc aattctgcac caactttttc aatttcaagg
    16501 ttagctgctt gttcacggta agcagtcaat tttggacgtc cagctttata gtcatttaca
    16561 aagtcatttg caaacttacc attttggatg tctgccaaga cagccttcat attttcttta
    16621 acttgttcag tgattacacg tggacctgat acatagtcac cgtattcagc agtgtttgaa
    16681 atagactgac gcattttctt gaatccacct tcgtagatca agtcaacgat caatttcatt
    16741 tcgtgaagaa cttcaaagta agccaattct ggagcgtaac ctgcttctgt caagacttcg
    16801 aaacctgctt cgataagggc agtcaaacca ccacaaagta cagcttgttc accaaacaaa
    16861 tcttcttcag tttcttcttt gtaagttgtt tcaagaagac ctacacgagc cgctccaaca
    16921 cctttacacc agtccatagc aatgttttta gcatttcctg ttgcatcttg gtatactgca
    16981 taaagagctg gaacaccaaa tccttcttcg taagtacgac gtaccaagtg tcctggtcct
    17041 ttaggagcac acatgaagac atctacatcc gcaggaactt tgataaattc aaagtggatg
    17101 ttgaaaccat gggcaaatcc aactgcgttt ccagcttcca agtttggagc gatttctgct
    17161 tcgtacaatt cttgttgaat ttcgtctggc gccaagatca tgataacatc agccaactta
    17221 gtagcttctg ctactgtgta agtatcaaat ccatcttctt ttgctttatc aaaagattta
    17281 cctggacgta caccgataat aacgtcacga ccggaataac gcaagttttg agcatgcgca
    17341 tgcccttgtg aaccataacc gataacggcg atttttttac cgtcaagtgc tgctacttta
    17401 acatcttttt catattccat ttgaactgtc atagcttttc tctcttttct attatttatt
    17461 gccttttagg ctggtttaat aaatttaagt tggattttta atcgcgggta aatccagttg
    17521 cacccgttcg agcaatattg cgaataccgt atgggcgaat gactcgcaat agggcttcgc
    17581 tcttttctgc atttcccgtc atctgaatgg taatcgagct tggcgctacg tctaccactg
    17641 ttgcacggaa aggttgaata atcgctaaaa tctcagctct cttctcagct ggcgctgaca
    17701 tcttaaccaa aatcacctcg cgctccaaat gaggcttgtc tgtaatatct cgaatgcgaa
    17761 tcacatcaat ctgacgattg agctgtttga tgatttgctc cacttcatca tgagaagcaa
    17821 catcaataat aatagtgata cgcgatacat tcggatcttc tgttgctcca acagagatgc
    17881 tttcaatatt aacctgacga cgagatagga cacctgtaaa gcgattgagt actcctgaac
    17941 gattttgtag ttttgctgtt aacattctac gcatggaact tcacccccaa catctcatga
    18001 ttactcttac cagccggtac cattggtaac acctgttcct tacgagaaat atctacctca
    18061 attagcatag gaacatcctc agtgatgact tcaaggtctt gagccaaggt ctcaggattg
    18121 tcaaacttat agtttttaat accataagcc tgcgccatca attggaaatc aggaagggta
    18181 tcaaagaccg actctgatgt tctgccttca tagaaggatt cctgccactg gcgaaccatt
    18241 ccaagtgaat gattgttcag cataaccacc ttgattggca ccttgtaaat attcaaaata
    18301 gccaactcct ggttggtcat ttggaaacca ccatccccaa caaacaagac tacttcctta
    18361 tctgggttag caattttagc accgattgct gctggaattc caaagcccat tgttcccaaa
    18421 ccacctgaag tcactaactg acgctcattt tggtagggat aatactgagc tgtccacatt
    18481 tggtgttgac caacgtctgt taccacaatg gcatctccat tcgtcaattc accaattcgt
    18541 tcaataactg cttgcggttg aaccacacgc tctttcttgt cataagaacg aacacgattc
    18601 ttgtctttag tgactttctc aatccacttt tcagtattgt tgtgaactgt tggttctgct
    18661 agcaacattt gcaaggcctt cttagcatct ccaactacag gaatgtctgc actgataatc
    18721 ttgccaatct cagctgggtc aatatcaatg tgggcaacct tagcattctt agcgaaagtc
    18781 ttaggattcc ccgtcaaacg gtcatcgaaa cgagaaccaa tactaatcat aaagtccgct
    18841 tccgtcatgg caatatttgc tgcgaatgac ccgtgcatgc ctcccattcc aagaaagagt
    18901 gggtgactcg ttgcaatcgt tccttgtccc aaaagactgg ttaccactgg aatttgatag
    18961 cgttctgcaa attcatttag ttccgtagca gcctcagcat aactaattcc accaccagct
    19021 aacaagactg gctttttagc cttggacaat tgcttcaaga ttttcttgat ttgcatatca
    19081 ttcggctcaa gagtcggctg ataacttggt aaattcactt ctggtgaata aatgaagtct
    19141 gtttctaaag cagatatgtc ttttggtagg tcaattacaa ctggccctgg acggcctgta
    19201 gttgcgatat ggacagcttc cgtaatgata cgcggaatat cagctgtctc acgaacttgg
    19261 taattgtact tagtgattgg catggtaatt cccacgatgt ctgcctcctg aaaggcatcc
    19321 ttcccaatcc ctgctcgcgc cacctgacct gtaaagacca aaaggggaac gctatcgctc
    19381 atggcatccg caatccctgt aatggcattt gttgctcctg gtccactagt gacgacggca
    19441 acacccaact ttccagttga tttggcataa ccttcagctt catgcaaaca accttgctca
    19501 tggcgcccta gaatgtggcg aatgccttta aaattatata tcgcatcata aaaaggcaaa
    19561 accgcaccac caggataacc aaagatggta tcaactccta aatcacgaag tgtttccaaa
    19621 actaggtccg accccgtctt aggagattct aaactgattt tctccattat tcccctttct
    19681 ttcctcttaa aaataacttg ttactatcat accatttttt caaaattttt caagataaaa
    19741 gaagaaattt tctgaatttt ctattttaac gtttatttat gaatgttatt tttgttttta
    19801 ttaaaaagat accgatttca tttactaaaa aagaaaaaag aactgatttc tcagtccttc
    19861 attaatctta ttccacacta aataggtatg ggtaaacagg ttgttgacct tggtgaatct
    19921 cgacttcaac gtcttcgaat tcttctacga tttcttgagc gatttcattg gcaagttctt
    19981 cgcttccgtc ttcaccgaca tagaaggtta cgatttcact gtcttcatcc aacatatgtt
    20041 tcaaggtttc agtcaatgtt tggtgcatat cagggtttga cacaagaatt tttccatcca
    20101 ccatacctag attatcgttt tcatggattt ctaagccatc gatcgttgta tcacgcacgg
    20161 ctgttgtgac gcttccgcta acaacatcgc taagagcagc tgtcatacgc tcttggtttt
    20221 cttcaatgga cttgcttgga tcaaaggcaa gaagacttgt cataccttga ggaagagtgc
    20281 gagcctctac cactactgct ggttgctcca aaacttctgc cgcagattga gctgccatga
    20341 agatgttctt gttgtttggc aagaagatga tgttacgggc attgacctgt tcaacagcct
    20401 tgataaagtc ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca taatccacgc
    20461 cttgagaaca gaagatatct gctagacctt taccagccac cacagcaatc aaagcatact
    20521 ctttttcttc agccgacttg ataacttgag tagcttcttt ctcaacctgt gcttcgtgtt
    20581 ggttacgcat attgtcaact tttaccttga ccaagctacc atatttgaga ccttcttgca
    20641 taacaagtcc tggatcttct gtatgaacat ggactttgac aatttcatca tcgttaacaa
    20701 cgaggagaga atccccaagc tcatccaagt agttacggaa ttcatcgtag tcaaaatctt
    20761 tagcataggt tggaccttgc ttaagagcta ccatgatttc agtacagtaa ccaaacgtga
    20821 tgtcctcagt cgctacgtga ccagctacag acttatgatg ctctacattg atcatctcac
    20881 tcatgttggc aggagtcgct acaaagtcct cagatgcaat atattcgcca gtaagggctg
    20941 aaaggaaacc ttcgtagatg aagaccaatc cttgaccacc tgagtccaca acgccaactt
    21001 ctttcaatac tggaagcatg tctggtgttt tagctagagc tgttttagca ccttccaagg
    21061 ctgcgcgcat gacttcaaca gcgtcatctg tttgctcagc ttttttctta gcaccgatag
    21121 cagctccacg agaaactgtt aaaatcgttc cttcaacagg tttcatcact gccttatagg
    21181 caacttccac acctgattgg aaggccagag ccaagtcttg acctgttaac tcgtctttat
    21241 ccttgatagc ttgggaaaat ccacggaaaa gctgagacgt aatcactcct gagttcccac
    21301 gcgcacccat caaaagccct ttggcaagaa tgctcgctac ttctccaact gtagaagctg
    21361 gcttgtctgc aacttcttta gcaccatttt caatggtcat tcccatattt gtcccagtat
    21421 ctccatctgg gactggaaag acgtttaatg aattgacata ttcagcttgc ttattcaagc
    21481 gagttgatgc agcctgcacc atttcttgaa ataagctagt agtaattttt gacacggtta
    21541 ttctcctaca actttgatat tttgaatgta gacatttaca gtctgagcag taattccaag
    21601 ctggttttcc aagctaaagg caacacgctc ttgaatgttt tttgacactt cactaatctt
    21661 tgttccgtag cttaacacgg tatatacatc aactgcaata ctgccatctt cggctgcctt
    21721 tacgacgaca cctttagaat aattttcctt acctagcagg gcttggaaat tatctttgag
    21781 ggcattttta ctagccatac cgaccacacc aaaaatctca gttgctgctc cacctacgac
    21841 ggttgcaatc acttcatctg ttagttcgat ttgaccatct tttgtattaa tttttacagt
    21901 catccttttt acctcaacta gttgatactc tattttatca tatttcagcc caagtgtaaa
    21961 agcagaatga tgtatcagcg gatatttact ctatttttca aacgatgtta tacccacaat
    22021 aaaagaaaaa agaccctaag gtctcctttg cttttattat taaacgcgtt caactttacc
    22081 tgatttcaaa gcacgagctg aagcccaaac ttttttaggt ttaccatcga taagaacagt
    22141 aactttttga aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt gtgaacggtt
    22201 gtttcctgat acagtcttac gacctgtaaa gtaacatact ttagccattg tgttttcctc
    22261 ctattagatc taatatagcg gatgtgctag caccacatac cgtactatgt tatcacactt
    22321 tcttgttttt tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc aggtcttgcg
    22381 tgacattttc tgctctccac atgccattgt tgattaacag aacaccagaa ttaaaattat
    22441 gtgtataaaa atcatctcta actgcagcta agggtatagc cgtcaagtcc aaatcccaca
    22501 gctcatctat cgattttctt acaacaatat ctgaatccaa atacagtaca cgagactcgc
    22561 ttacatactt tggaataaaa tacctaaaaa aagccgcata tgaaagtccc tcaaagggga
    22621 gacgataacc tttcagaata ctactgtcaa tctgaacatt cacaatctca ctattcaaag
    22681 tctctagtct tttttccatc aattggaacc attctcgcgg aaggtcatca ttaaaaacat
    22741 aaaacttaag attataatga tgaacacaaa gagattttat tgttgtttca actttatcca
    22801 tataagcatt atctgcacct aagacaatcg cttttttctc ttctttcact ctttatctta
    22861 tttcttttta ttcccatcat attattccca tcatatgttt ctacgtaacc attattttcg
    22921 cctattcgtt cgtaaaacca taccagtgga gattttagat gaagtcccat tacggtttac
    22981 attttttaca ttacgacacg gagttttaca aatcgatttc atttgccaaa cgtagttagt
    23041 gaggcagtta gctagttcgc caaatagcga ctagcgtcca acaatttgga actttagttc
    23101 caattgttgg tactgagtca catcttctcc tctaactcta cgtctggata cttgtccgca
    23161 aaccagcgga gggcaaagtc attttcaaag agaaagactg gttggtcaaa acggtctttg
    23221 gctaagatat tgcgacttga cgacatccgt tcatccaagt cctcaggctt gatccaacga
    23281 acggtctttt tacccattgg gttcataact acttccgcat tgtactcgct ttccatgcgg
    23341 tgtttaaaga cttcaaactg gagttgacct acagcgccta gcatgtactc acctgtttgg
    23401 taattcttat aaagctgaac ggctccttct tgcaccaatt gctcaatccc cttgtggaag
    23461 gatttttgct tcataacatt cttagcagaa actttcatga aaatttcagg agtaaaggtt
    23521 ggcagtggtt caaattcaaa cttgtttttt ccaaccgtca aggtatcccc aacctgataa
    23581 gtaccggtat cgtaaacccc gataatatca cctgccacgg cattggtcac attctcacga
    23641 ctctccgcca taaactgggt aacattagat agtttggcac ccttaccagt acgagggaga
    23701 ttgacactca tgccacgctc aaattcgcct gatacgatac ggacaaaggc aatacggtca
    23761 cggtgacgag gatccatgtt ggcttggatt ttaaagacaa agcctgagaa atccttgtca
    23821 taaggatcca caatttcacc gtctgttttc ttgtgaccat gtggttctgg agcaaacttg
    23881 aggaagattt caaggaaggt ctgcacacca aagtttgtca gggctgaacc gaaaaagaca
    23941 ggcgtcaatt ctccagccag aatagcttcc tctgaaaact cattcccagc ttcatttaaa
    24001 agctcaatgt catccttgac ttgctcgtag aaaggattgc taccaaaaag tttgtctcca
    24061 tcttctaggc tagcaaaacg ctcatcccct ttgtaaagct ctaaacgttg gttatagagg
    24121 tcatacaagc cctcaaaggc tttccccatc ccgataggcc agttcatagg gtagctagca
    24181 atgcccaaga tttcttccaa ttcttgcaag agatccaaag gctcacgacc gtcacgatcc
    24241 aacttgttca taaaggtaaa gactggaatg ccacgatgtt tcacaacctc aaacaatttc
    24301 tttgtttgag cctcgatccc cttggcagag tccacgacca tgaccgcagc atccaccgcc
    24361 atcaaggtac gataggtatc ttctgagaag tcctcgtgcc ctggcgtgtc taagatattc
    24421 acgcgcttgc cgtcgtagtc aaattgcata acagatgaag taacagaaat cccacgttgc
    24481 ttctcgatat ccatccagtc agatttagca aaagtccctg ttttcttccc ttttaccgta
    24541 ccagcatcac gaatctcacc cccaaagtag agtaactgct cagtgatggt tgttttcccc
    24601 gcgtccgggt gggagataat ggcaaaggta cgacgtttct taatttcttc ttgaatattc
    24661 ataagttctc tttctttgat tctctatttt tcttgtttca atagctgaga atgattttta
    24721 cattggattt taccattcct ttcgacactc cattatatcg gattttagca tttttttcaa
    24781 tttctatttc ttttcacttc cccctccctt atttatagga aaatatggta aaatagaaca
    24841 gactaaaaat catcatttca cgaaaggatg caagatgaaa attacgcaag aagaggtaac
    24901 acacgttgcc aatctttcaa aattaagatt ctctgaaaaa gaaactgctg cctttgcgac
    24961 caccttgtct aagattgttg acatggttga attgctgggc gaagttgaca caactggtgt
    25021 cgcacctact acgactatgg ctgaccgcaa gactgtactc cgccctgatg tggccgaaga
    25081 aggaacagac cgtgatcgct tgtttaaaaa cgtacctgaa caagacaact actatatcaa
    25141 ggtgccagct atcctagacg atggaggaga tgcctaatga cttttaacaa taaaactatt
    25201 gaagagttgc acaatctcct tgtctctaag gaaatttctg caacagaatt gacccaagca
    25261 acacttgaaa atatcaagtc tcgtgaggaa gccctcaatt catttgtcac catcgctgag
    25321 gagcaagctc ttgttcaagc taaagccatt gatgaagctg gaattgatgc tgacaatgtc
    25381 ctttcaggaa ttccacttgc tgttaaggat aacatctcta cagacggtat tctcacaact
    25441 gctgcctcaa aaatgctcta caactatgag ccaatctttg atgcgacagc tgttgccaat
    25501 gcaaaaacca aaggcatgat tgtcgttgga aagaccaaca tggacgaatt tgctatgggt
    25561 ggttcaggtg aaacttcaca ctacggagca actaaaaacg cttgggacca cagcaaggtt
    25621 cctggtgggt catcaagtgg ttctgccgca gctgtagcct caggacaagt tcgcttgtca
    25681 cttggttctg atactggtgg ttccatccgc caacctgctg ccttcaacgg aatcgttggt
    25741 ctcaaaccaa cctacggaac agtttcacgt ttcggtctca ttgcctttgg tagctcatta
    25801 gaccagattg gaccttttgc tcctactgtt aaggaaaatg ccctcttgct caacgctatt
    25861 gccagcgaag atgctaaaga ctctacttct gctcctgtcc gcatcgccga ctttacttca
    25921 aaaatcggcc aagacatcaa gggtatgaaa atcgctttgc ctaaggaata cctcggtgaa
    25981 ggaattaacc cagaggttaa ggaaaccatt ctaaatgccg ctaaacactt tgaaaaattg
    26041 ggtgctattg tcgaagaagt cagccttcct cactctaaat acggagttgc cgtatactac
    26101 atcatcgctt catcagaagc ttcatcaaac ttgcaacgct tcgacggtat ccgttacggc
    26161 tatcgcgcag aagatgcaac caaccttgat gaaatctatg taaacagccg aagccaaggt
    26221 tttggtgaag aagtgaagcg ccgtatcatg ctgggtactt tcagtctttc atcaggttac
    26281 tacgatgcct actataagaa ggctggacag gtccgtacac ttatcattca agatttcgaa
    26341 aaagtcttcg cggattacga tttgattttg ggtccaactg ctccaagtgt tgcctatgac
    26401 ttggattctc tcaaccatga cccagttgcc atgtacttag ccgacctatt gaccatacct
    26461 gtaaacttgg caggactgcc tggaatttcg attcctgctg gattctctca aggtctacct
    26521 gtcggactcc aattgattgg tcccaagtac tctgaggaaa ccatttacca agctgctgct
    26581 gcttttgaag caacaacaga ctaccacaaa caacaacccg tgatttttgg aggtgacaac
    26641 taatgaactt tgaaacagtc atcggacttg aagtccacgt agagctcaac accaattcaa
    26701 aaatcttctc acctacttct gcccactttg gaaatgacca aaatgccaac actaacgtga
    26761 ttgactggtc tttcccagga gttctaccag ttctcaataa aggggttgtt gatgccggta
    26821 tcaaggctgc tcttgccctc aacatggaca tccacaaaaa gatgcacttt gaccgcaaga
    26881 actacttcta tcctgataac cccaaagcct accaaatttc tcaatttgat gaaccaatcg
    26941 gatataatgg ctggattgaa gtcaaactag aagacggtac gaccaagaaa atcggtatcg
    27001 aacgtgccca cctagaggaa gacgctggta aaaacaccca tggtacagat ggctactctt
    27061 atgttgacct caaccgccaa ggggttccct tgattgagat tgtatctgag gcagatatgc
    27121 gttctcctga agaagcctat gcttatctga cagccctcaa ggaagttatc cagtacgctg
    27181 gcatttctga cgttaagatg gaggaaggtt cgatgcgtgt ggatgccaac atctcccttc
    27241 gtccttatgg tcaagagaaa ttcggtacca agactgaatt gaagaacctc aactccttct
    27301 caaacgttcg caaggggctt gaatacgaaa tccaacgtca agctgaaata cttcgctcag
    27361 gtggtcaaat tcgccaagaa acacgccgtt acgatgaagc taacaaaaca accatcctca
    27421 tgcgtgtcaa ggaaggggct gcagactacc gctacttccc agaaccagac ctacccctct
    27481 ttgaaatttc tgacgagtgg attgaggaaa tgcggactga gttgccagag tttccaaaag
    27541 aacgtcgtgc gcgttatgta tctgaccttg gtttatcaga ctacgatgct aatcagttga
    27601 ctgctaataa agtcacttct gacttctttg aaaaagctgt tgccctaggt ggtgatgcca
    27661 aacaagtctc taactggctc caaggggaag tcgctcagtt cttgaatgct gaaggtaaaa
    27721 cactggaaca aatcgaattg acaccagaaa acttggttga aatgattacc atcatcgaag
    27781 acggtactat ttcatctaag attgccaaga aagtctttgt ccatctagct aaaaatggcg
    27841 gtggcgcgcg tgaatacgtg gaaaaagcag gtatggttca aatttcagat ccagctatct
    27901 tgatcccaat catccaccaa gtctttgccg ataacgaagc tgctgttgcc gacttcaagt
    27961 caggcaaacg taacgccgac aaggccttta caggattcct tatgaaggca accaaaggcc
    28021 aagccaaccc acaagttgcc cttaaactac ttgcacagga attggcgaag ttgaaagaaa
    28081 actagacaga acaaaaccag ccctaaggtt ggttttttct tgacaaatag aaagaaaacg
    28141 tttacaatat tgcgtgtaaa gtttccaaac aagaaaacta aaaatcgcaa caataaggag
    28201 ttatttatat ggctacaatg aaggcagctc gctggcatgc agcgaaagat gttcgtattc
    28261 aagaaataga agttcctgaa gtacttccgc accaagtaaa agttgcagtt aagttcacag
    28321 gaatttgtgg tactgacctc catgaatttt tagatggacc tatctttatc ccaacagatg
    28381 agcacgtcta ttctggtcaa aaagcaccgg taacactggg acatgaattt tctggtgaaa
    28441 tcatagaagt cggaagcgat gttacccgtg ttaaagttgg tgatcgtgtt gctgtggaac
    28501 caattctagc taaaaataac ttagttggtg attataattt ggatccaaac cttaattttg
    28561 tcggtttggc tgcagacggt ggatttgcca aatattgtgt tttagacggt gacttagtac
    28621 atgtcattcc agatagcttg agctatgaac aagctgctct tactgaaccc gctgctgttg
    28681 cagtctatgc tgttcgtcaa tcttctttga aggctggcga tacagctgtt gtctttggtt
    28741 taggcccgat tggtctatta attgtagaag ctcttcgtgc agctggtgct tctaagattt
    28801 atgctgttga actatcacct gaacgtcaag caaaagctga agagttagga gctatcgttg
    28861 tccgtccgga agaaggtgaa acagctgttg aagctattca tcgtttaaca aacggtggtg
    28921 tagatgtttc ttatgaagta acgggtgtgc cagtagtttt aggacaagcc ttagctgccg
    28981 tacataaagc aggtgagtgc atggtggtct ctatctggga acgagaagca aatattaatc
    29041 cgaatgaatt tgcaatccaa gaaaagacac taaaaggaat catcgcttat cgtcatatct
    29101 tccctaaagt attagaattg atggaacaag gctacttctc tgctgaaaaa ttagttacta
    29161 agaaaattaa attggaaaat atcgtcgaag aaggctttat cgaattaact caagataagt
    29221 cacaaattaa aattttggta gaaccagaat aaaaaatcaa tctttttaag acaatactaa
    29281 caggtcggag taaacttact tcggcctttt gaaatataat actcttcgaa aatctcttca
    29341 aaccacgtca gcgtcacatt accgtatata tggttactga cttcgtcagt tctatccaca
    29401 acctcaaaac agtgttttga gcagcctgcg gctagcttcc tagtttgctc tttgatttcc
    29461 attgagtatg agaagaaata tagtggatac tctttaacat taaccactcc acctgactag
    29521 ccaatattct ttttcgctcc taccaactcc caataactat tttggcttta tttccagagt
    29581 attttatggt aaaatgaaga gtaataatat ttgttaaaga ggtaaaaaca tgattgaagc
    29641 aagtaaatta aaagctggta tgacctttga aacagctgac ggcaaattga ttcgcgtttt
    29701 ggaagctagt caccacaaac caggtaaagg aaacacgatc atgcgtatga aattgcgtga
    29761 tgtccgtact ggttctacat ttgacacaag ctaccgtcca gaggaaaaat ttgaacaagc
    29821 tattatcgag actgtcccag ctcaatactt gtacaaaatg gatgacacag catacttcat
    29881 gaatacagaa acttacgacc agtacgaaat ccctgtagtc aatgttgaaa acgaattgct
    29941 ttacatcctt gaaaactctg atgtgaaaat ccaattctac ggaactgaag tgatcggtgt
    30001 caccgttcct actactgttg agttgacagt tgctgaaact caaccatcta tcaaaggtgc
    30061 tactgttaca ggttctggta aaccagcaac gatggaaact ggacttgtcg taaacgttcc
    30121 agacttcatc gaagcaggac aaaaactcgt tatcaacact gcagaaggaa cttacgtttc
    30181 tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt gaagaacaac ttggcgaaat
    30241 cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatc gctactgcaa aggtagaggg
    30301 tgttcactct ttttcaaaca gatcagtgtc tgataccctt tcaaaacttt cactcggccg
    30361 tggcatttat cttaaaaacg tggacgaaga actcacagca gatatctatc tctaccttga
    30421 gtacggagta aaagttccta aggtagcggt tgctatccag aaagctgtca aagatgccgt
    30481 ccgtaatatg gctgatgtag aactcgctgc tatcaatatt cacgttgcag gtatcgtccc
    30541 agataaaaca ccaaaaccag aattgaaaga tctatttgac gaggacttcc tcaatgacta
    30601 gtccactatt agaatctaga cgccaactcc gtaaatgcgc ttttcaagct ctcatgagcc
    30661 ttgagttcgg tacggatgtc gaaactgctt gtcgtttcgc ctatactcat gatcgtgaag
    30721 atacggatgt acaacttcca gcctttttga tagacctcgt ttctggtgtt caagctaaaa
    30781 aggaagaact agataagcaa atcactcagc atttaaaagc aggttggacc attgaacgct
    30841 taacgctcgt ggagagaaac ctccttcgct tgggagtctt tgaaatcact tcatttgaca
    30901 ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc aaaggacttc tccgatcaaa
    30961 aatctgcccg ttttatcaat ggactgctca gccagtttgt aacagaagaa caataaaaag
    31021 aaaaagtgtt tgatagatat caaacacttt tttctttgcc tcccactatc taaaaaaatg
    31081 ataatagata taattgtaaa caaaaatcca gataggtttt gcatgattga gaaagttaaa
    31141 aaaactatgg cagagaatcg ttaatctcag attgtcggta gaacgataaa caagggcaaa
    31201 aaagaaacca atcagactat aatataataa actaattgga tctctgtgag atagtatcaa
    31261 atggctaatc ccaaagatga tagcagatag gataacatcc aaatagtact tggactaggg
    31321 aaagaaggta ttcataaaat accctctatc aagagtctcc tcaaaaacag gaccgatgat
    31381 tacaggcagg acaaaagata agatagtcga taaaaaggtt ggttgtccat ttgaaaaaag
    31441 cacggtaaaa tactcatcat gaatattcct atgattaatc aaatgagcat agcgtgccca
    31501 aaaattaccg agaatctgat aaaccacata agttgcaaat aagtagaaga caaatgacca
    31561 gttccagctc tttttctcaa agataaagag catctttttc ttttttaacc tccaaattaa
    31621 tagaaggaaa cttcccacta atcccattgt taaaataaga gaatagacat cagctcctaa
    31681 ccctaaaatg atcgtcacat acaatccaat tgtttgtggt aaataggtag atagtaaaat
    31741 aataagcaaa aatattccaa attgtcttag tttttttgtg tttctcatcg tacttttttg
    31801 aaagattacc ctgctcggaa gccgtacttc caagcatcta tataagaatt aagtgcccct
    31861 tgcctcatat agggagcaaa ttctctataa tataaccatc tactatatcc atcttcccaa
    31921 acagcaagac cacctgaagt ttgctccaag tcctcagttg aaagaactgt aaatgtattt
    31981 gtacctgtca ttgcaagtac cttcttaaaa tagattgttg taggctcaca tttatagtat
    32041 atttcttttt ttgtctattt tatagcccat ctcctcaact ggcaattttt cgacctgaat
    32101 tacatttttc cataaaaaat gagacctttc tagtctcatt tagtcattct tagtattttc
    32161 taaatcgttg atagcgttct tccagcaact cttctagcgg tttttgtgaa agtctagcca
    32221 gctctgtttg gagttctttt ttgacactct taatcagttc tttactagaa agtcctattt
    32281 cagaaatcac cttatctacc acgtccattt ctaacagttc atgcgaagtg attttcatca
    32341 gttctgctgc ttccatagcg cgagtaccgt ccttccataa aatggaagca aagccttctg
    32401 gactgagaat ggcatagata gaattttcca gcatccagac acggtccgcg acagctagag
    32461 ccagagcccc gcctgaacca ccttcaccga taataatggc gataatagga actttcaggt
    32521 cactcatttc catgagattg cgagcgatag cttccccttg accacgttct tccgctccga
    32581 caccaggata agcacctgct gtattgataa aggtcacaac tggacggcca aatttctcag
    32641 cctgtttcat caaccgcagt gcctttcggt agccttctgg atgtggttgg ccaaaattcc
    32701 gtttgaggtt gtcttgcaaa ctcttgcctt tttggatacc aaccactgtt acagcttgat
    32761 ctccaagcca accaatacca ccaacaactg caccatcatc acgaaaagaa cggtcaccat
    32821 gtaattggat aaattcatca aaaatgcctg tcgcaaagtc caaggttgtc aagcgactct
    32881 gctcacgcgc ttctctgact atttttgcaa tattcatcta ggactccctc catgcaatct
    32941 gactaggcta gcaatcgtat ctggtaagtc tcttcttttg acaatagcat ccacaaagcc
    33001 atgttctaat aggaattctg ccttttggaa atcctcaggc aagctttcac gaaccgtatt
    33061 ttcaatcaca cgacgcccag caaaaccaac caagctctgt ggttcagcca gaatgatatc
    33121 gccttccata gcgaaagaag ctgtcacacc accagtcgtt ggatctgtca aaatggtcag
    33181 gtaaaagaga ccaacatttg aatggcgttt aaccgccgca gagatcttag ccatctgcat
    33241 gagactcatg attccttcct gcatacgggc tccaccagag gctgtgaata ggacaactgg
    33301 caatttttcg acagtcgcat actcaaacaa acgagtgatt ttttcaccta caaccgtacc
    33361 catagaagcc atgataaagt tagaatccat aatcccaaga gccacagtct gacctttaat
    33421 aagagcagtt cctgtcacaa cggcttcatg cagacctgtt ttttcacgca tagatgccag
    33481 tttcttttgg taaccaggga aatgcaaggg atccttgctt tcaatccctg taaacaattc
    33541 tttgaaggtt cccatatcaa tcgtcaaagc caagcgttct tgggcagaaa tacgaaaggt
    33601 atagctacag tgcggacaga tacgttcact tcccagatcc ttctgataga tggtatgctt
    33661 acagcctgga cactgggaaa ataattcatc tggaacctct ggcttagctt gaggtttttc
    33721 cctaaccgaa cgattgggat tgattcgaat atacttatct tttttactaa atagagccat
    33781 tgattcccct tttcggttta aactcttaaa gtcattttat tctttttctt gatatttagg
    33841 taagaaggtt tccatcaaga aggaagtatc ataatcccca gcaatgacat tgcgatctga
    33901 aatgaggtca agctggaaat ctgcattggt ctgcactcct tcaatctcta attcatagag
    33961 ggcacgttgc attttcatca aggcgtcaaa acgattttcg ccgtgtacta tgattttggc
    34021 aatcatacta tcataataag gcggaatggt ataacctgga taaactgctg aatccacgcg
    34081 caaaccaact ccaccacttg gcagatagag attagtaatc ttacctggac ttggagcaaa
    34141 gttaaaggct gggttttctg cattgatacg acactcgatg gcatgaccac gtaggacaat
    34201 atcttcttgc ttaacagaca aaggctgacc tgccgcaatg caaatctgtt ccttaacgat
    34261 atcaacacct gaaacaaact ctgttactgg atgttctacc tgaacacgag tattcatctc
    34321 catgaaatag aaattgctac ttgcttcatc aagaagaaat tcaatggttc ctgcattctc
    34381 atagccaaca aactctgccg ctcgaacagc agcagcacct atttcatgac gcagcgtttt
    34441 tccgattgca atcgagggac tttcttccaa aaccttttgg ttattccttt gaagagaaca
    34501 atcccgttca cccaagtgaa tcacatgtcc atgctcatca cctaggattt gaacctcaat
    34561 gtgccgagct ggatagataa cccgttctat gtacatggca ccattgccat aattggcctt
    34621 ggcctcacta gaggcagttt caaaggcaga aacgaggtca tctggttttt caaccttacg
    34681 aatcccttta ccacctccac ctgctgaagc cttgagcata acaggatagc caattttttc
    34741 agcaacaatc aaagcttctt cagagttatg cacttctcca tctgaacctg gtataacagg
    34801 cacacctgct ttaatcatct gagcacgcgc attgatctta tcccccatca tatccataac
    34861 atgaccagat ggaccgataa acttgatacc tacttcttca cacatggtcg caaatttgga
    34921 attttcactg agaaatccaa aaccagggtg aatagcttct gcctcagtca agactgcagc
    34981 tgatagaact gcattaatat tgagataaga ctctgttgcc ttgccaggac caatacaaac
    35041 tgcttcatct gccaaaagcg tatgaagagc ttccttatca gcagttgaat aaaccgctac
    35101 cgtcgcaatc cccaattcac gtgccgcacg gataatacga accgcaattt caccacgatt
    35161 ggcaattaaa atttttcgaa acatggagaa cctccttagt tcccaattgc aaaagtaagg
    35221 ataccactgg ctgcaagctt gccatccact tcagcctttg cttcaaccac agctatggtg
    35281 ccacgacgtt ttacaaaagt cgctgtcata accaattggt cgcctggtac aacttgcttc
    35341 ttgaacttaa ccttgtccat accagcgtaa aagaccagtt ttcctttatt ttcaggtttt
    35401 gataactcca acacaccagc agtttgcgcc aaggcttcca taatcagaac acctggcata
    35461 actgggtatt gaggaaagtg gccgttaaag aaaggttcgt taatggtcac atttttgata
    35521 gcaacaatgg tatcctcgct cacttccaag acacggtcca ctagaagcat aggataacgg
    35581 tggggaagag cttctttgat tccttgaata tcgatcattt gatacgtacc aatcctttac
    35641 caaactcaac catttcttcg ttagagacga gaatttccgt taccacacca tccttaggag
    35701 ctgggatttc attcatgact ttcatggctt cgataattac caatgtttga ccttttttga
    35761 cactatcacc aactgtaacg aaggcaggtt tatctggtcc agcagccaag taaaccactc
    35821 caacaagtgg actctctaca agatttccct cactagccac acttgcttca gctggagctg
    35881 gaacttcttc tgctacagtc tctgctggag cagatgtagg agctactgga ttcggtgttg
    35941 ctagaacggg tgctggagcg acttgagttg caacttcagg cacaggtctc gcttcattct
    36001 tgctaaactg caactcatcc gtcccatttt tataagaaaa ttctctcaaa cttgactggt
    36061 caaattgagt catcaagtct ttaatatcgt ttaaattcat acttatctat tctcccaacg
    36121 tttgaaagca agaactgcat tgtggcctcc aaaaccaaaa gtatttgaaa tagcgtatgg
    36181 aatttctttc tccaagcctt gtccataaac gacattagct tcgatataat ctgatacttc
    36241 acttgtccca gctgtcattg gtacaaagtt atgacgcata gcttcgatgg tgacgatagc
    36301 ttctactgca cccgcagccc ccagcaaatg tcctgtaaaa gacttggttg atgatacagg
    36361 tacttcctta ccaagaacag ctacgatagc accactttct cctttttcat tggcaggagt
    36421 tgacgttccg tgagcattga cataggctac ttgctctgga gaaatctcag cttcttccaa
    36481 ggctagtttg atggccttga tagctccctg accttctgga tgtggagaag tcatgtggta
    36541 ggcatcacaa gtatttccgt aaccaaccac ttcagccagg atagtagctc cacgtttttc
    36601 agcgtgttca agactttcta gaaccaacat ccctgaacct tcacccataa caaacccatt
    36661 gcgatcctta tcaaatggga tcgaagcacg agttggatcc tctgtagtag agagagctgt
    36721 taaggcttgg aaaccagcga tggcaaaagg tgtgatagaa gcttctgttc ctcccaccaa
    36781 catcacatct tggaaaccaa acttaatgga gcggaaggca tccccaatcg catcatttga
    36841 tgaagagcag gcagtattga tagatttaca aacaccgttt gcaccaaaac gcatggctac
    36901 attcccagaa gccatatttg gtaaagcttt tggaagagtc attggtttga cacgtttggg
    36961 tcctttttca tgaaggcgaa gtacctgatc ttcaatttcc ttgattccac caataccaga
    37021 tgcaacgata acaccaaaac gatccctatt aagagcctct acatcaagat tggcatgatt
    37081 tacagcctct tgggctgcat acaaggcata taaagaatag ttatcaaaac ggttggtatc
    37141 tttttttaca aagtatttat cgaacggaaa atcttggatt tctgccgcat tatgcacatc
    37201 aaagtcacta tgatcaaatt ttgtaatgcc accaatgccg attttcccag ttgctaaact
    37261 attccaaaat tcttctggtg tatttccgat tggagatgtt actccataac ctgttaccac
    37321 tactcgattt agtttcattc ttttcacctc tagctttcgc tacatactta agccaccatc
    37381 aatggcaacc acttgaccag ttagataatc ttggcctgct aaaaatactg tcaaatctgc
    37441 aacctgctct gcctgcccaa attctttcat cggaatctga gctagtgtag cttccttaat
    37501 cttatctgat aagatagctg tcatatcaga ctcaatcatt cctggagcaa tcacattgac
    37561 tcgtatattc cgactagcga cctcgcgtgc cacagacttg gtaaagccaa tcaagccagc
    37621 cttagaagca gcatagttag cttgaccaat attccccatc aaaccaacaa cactagacat
    37681 attaatgata gcaccttctc tggctttcat catcggtttc aagactgatt gtgtcatatt
    37741 aaaggcacca gtcagattga ccttgagcac tttttcaaaa tctgcttctg tcatcttgag
    37801 cataagagta tcttgggtaa tccctgcatt gttgaccaaa acatctactg aacccagttc
    37861 tgcaatagct tgatcaatca tacgcttagc gtctgcaaaa tctgatacat ctcctgaaat
    37921 gggaaccacc ttgataccat agtttgaaaa ctcagcgagc aattcttctg agattgcccc
    37981 acgactgttt aagacaatgt tggctcctgc ttgagcaaac ttgtgggcga tggcaagacc
    38041 aattccacga ctcgaacctg taataaagat atttttatgt tctagtttca tttttttcct
    38101 ttcaaaactt ctacttattt tagtctattt ttctaaaagt gctactaaac tcgcttgatc
    38161 ttccacatga gctaagtgag cagtttgatc aattttttta acaaaacctg acaagacttt
    38221 ccccggtcca atctcgataa agttgcttat gcctgcttct tgcatgaccc caatactttc
    38281 atagaaacga acgggttcct tgacctgacg cgtcaagagc tgagcaatgt cctctttttg
    38341 catcacagca gcttctgtat tgccgactag gggacaagta aaatctgaaa aacttacctg
    38401 agctagagtt tcagctagtt tctggctagc aggctcaagg agagcggtgt gaaagggacc
    38461 tgacacctta agaggaatca agcgtttggc acctgcttct tgcaaaagtt caaccgctcg
    38521 atcaactgca accacttctc cagcaatgac gatttgtgca ggtgtgttat agttggctgg
    38581 agtaaccact ccaagttcag aagctttttg acaggcttct tcaatgacct ctactggcgt
    38641 attgagaact gctaccatct tgccagagtc agcaggagcc gcttcttcca tataggctcc
    38701 acgcttagct accaaggcaa ccgcatcttc aaaatccaag gcgccgcttg ccaccaaggc
    38761 agagtattct ccaagagaca aaccagcaac catatcaggc tgatagccct tttcttgcaa
    38821 taaacggtag atagcaaccg aagtcgctag aatggctggt tgcgtatagc gggtctgatt
    38881 gagtttgtct tcttccgtat cgatgagata acgtaaatca taaccgagca cctgactcgc
    38941 tcgatcaatc gtttctttga caatcggata ctgatcatag aaatcccgtc ccatccctag
    39001 atactgggca ccttgaccag caaataaaaa ggctgtttta gtcatttctt acaactcctg
    39061 cccagcgaga ggcttcttct tgaattttct tagcggctcc gtaatacaaa tcttttagga
    39121 tttcttcagc tgtttcttct ttagaaacaa gccctgcgat ttgacctgcc atgacagagc
    39181 caccatccac atcaccgtga acaactgctt tggctagggc acctgctccc atttgttcaa
    39241 agatttctaa atcaggatct tcctgcttaa aggcatcttt ttcagccagt tcaaaatctc
    39301 tagtcaactg atttttaata gcacgaacag catgaccaaa gtgctgagct gaaatcgtag
    39361 tatcaatatc ccttgctttt aaaattttct ccttgtagtt tggatgggca ttcgactctt
    39421 ttgcaactac aaaccgtgtc cccacctgta cagcctctgc acctagcata aagccagccg
    39481 cagcaccttc accatccgca attcctcctg cagcaataac aggaatagat atagctgtgg
    39541 ctacctgtcg caccaaggtc atggttgtta atttaccgat atgcccccca gcttccattc
    39601 cttctgcaat aacagcgtct gcaccgattt tttccatgcg tttagctaaa gcgacactag
    39661 gaacaacagg aataacgatt atcccagctt catggaaacg ttccatatac ttgcttggat
    39721 ttcctgctcc tgttgtgaca actttaacac cttcttcaat aacgagatcc acgatatctt
    39781 ccacaaaggg agataagagc atgatgttga ccccaaaggg tttatcagtc aatgatttga
    39841 ttttatcaat attggccttg acaacttctt tcggggcatt tcccccaccg ataattccta
    39901 atcctccagc cttggaaaca gcccctgcca aatcaccatc agcaacccag gccatccctc
    39961 cttggaaaat aggatagtca atcttcaata attctgtaat acgcgttttc atagtgcctc
    40021 caaccttcct tgcttacgta atagttcgat ttcaccataa tttgacagtc aaactattac
    40081 ctaaacaaga gggagtgggt ttctccctac tccttctact aatattctgc ttattttgct
    40141 tgctcttcaa cgtaagcaac caagtcacca actgttttca agtcattttc tgcttcgatt
    40201 tggatatcaa aagcatcttc gatttctgag attacttgga acaagtccaa tgaatctgcg
    40261 tccaaatcat caaaagttga ttcaagtgtt acttctgatg cgtcttttcc aagttcttca
    40321 acgataattt cttgtacttt ttcaaatact gccatgatag gactccttta aaataaatag
    40381 tttttttata acaatgtgtt caccacatga ttacctaaat tgtaagaatg agcgtgcccc
    40441 aggtcaagcc tccaccgaag cctgatagaa gaacagtctg gctaccatct aaagggatga
    40501 gaccttgttc tacacactct gaaagtaaaa tcgggatact ggctgcactg gtattgccat
    40561 attccatcat attggctgga agtttggctc ggtcaacacc aatttttcta gccatcttat
    40621 ccaaaatacg gtcattggct tgatgaagta gcagataatc caagtctgtc acctctatag
    40681 gagattcatc aatagtctgc ttgatagact tggctacatc tcgaatggca aaatcaaaga
    40741 ctgtgcgtcc atccatcttc aaaaacgaat ctgcactttc ttgatctgaa aatggagaat
    40801 gcaaacctga atgcccataa gttaaacact cgctgcgact tccatcgcta ttgagactct
    40861 cagctaagaa atgctcttgc tcgctagctt ctaacaagac accaccagca ccatctccaa
    40921 acaacacagc tgttgatcga tccgaccaat cgactgcctt agagagggtt tcactaccaa
    40981 tcaccaagcc tttttgaaag cgaccagaag cgataaactt ttcagcagtt gaaagagcaa
    41041 atacaaatcc actgcaagcc gcggttaagt caaaagcaaa ggctttatta gcgccaatat
    41101 tagcttgaac acgagcagct gtagagggca tcatcgaatc tggagtaatg gtagctagga
    41161 tgataaaatc cagttctttt cctgttattc cagcttttgc catcagtttc ttagcaacct
    41221 ctgtagccaa atcactggta gattctgttc ttgaaatatg cctttgtcgt attcccgttc
    41281 gacttgaaat ccactcatca ttggtatcca taatctgagc caagtcgtga tttgtaacca
    41341 cttgctctgg cacataatga gcaacctgac ttatttttgc aaaagccatt atttcaaatc
    41401 ctccaaaaat tggtaaagat tagtcaagcc tttacccatg acagcaattt cttcctcgct
    41461 catgccatca ataatttttt ctaccatggc cttgtggaag cgtttatgca gtctatgaat
    41521 caagcgaccc ttctttgtca aatgcagatg caccacacga cgatcctgtt ctgaccgaac
    41581 tcgctcaatg tagcccttac gctctaaatt gttcaaactt gtcgtaacag ttccaagagt
    41641 taccatcaac tcttttgaca cttgacttgg agtcacatct ggagccttac cgatgacatc
    41701 aatcgtatgc atttctttga tggagatatc cttaaaacga ctacctctca agttcacttc
    41761 ctcaattaca aggacattgt taaatataga tgttaaatat tcattgattc gttggtagtc
    41821 catttttcat atccctcctt cttcaaaaaa cttttacaat caaaacattt gacagaaaga
    41881 attatatcaa aattcaaaga atgatgcaag tattttttat tttcctgtaa atttaggtct
    41941 tcttctctcc gaatgagctc gcactccttc tttgaaatcc tctgtttgag ctaaggattt
    42001 ctgtaggttc agttctaaag tagcgtaacc ctgccagtct ttaaactggc tctcccaaac
    42061 caacttctta atggcagcat aggaattact tgaagcacgt cttaattttt taagaagctg
    42121 ttctctcgtc ttttcaagtt tttcagcttc agaaacgcgg taaaccaacc cccattctag
    42181 ggctttttct gccgttaaag cctctcctgt catagctaat tgagcagcac gcgtcacacc
    42241 gatactgcgg ctcaagagat gaattccccc tgcatctgga gccaaaccaa caccaacaaa
    42301 ggcttggata aacttagcct tatccgtcgc caaacagaaa tctgccgcaa cagccatatt
    42361 cgctgcggca cctgcaacag caccgtcaac ttccattaaa acaggtttgg ctatttgctt
    42421 gattttataa gaaatcgtat tgaccaactc tgcgattttt gtcaatgatg gaatatcatc
    42481 ctcatccact gcccgcttca tctctaccaa atctccccca actgagaaga cctttccatt
    42541 ggcattgatt aagataaaat gcacagctgg attttcttct gccaaagtca gagcttctaa
    42601 aatctcctca cacatgggaa tatgaaaacc atttgcgacc tcaggacggt tcaaggtaag
    42661 gattgccaag tcctcttcaa gctgataaat aatgtgttcc atcagggctc ctttttattt
    42721 tataagcagt ttatactctt cgaaaatctc ttcaaaccgc gtcagcttcc atctgtaacc
    42781 tcaaaacagt attttgagca gtctgcggct agcttcctag tttgctcttt gattttcatt
    42841 gagtgttaaa ttatttcact gtcaaagtat atctttttta ggagcagaaa gcaagaaaaa
    42901 atcgactgaa agtgtctcag ccgataagaa aggctcgctt taggctagaa agcatcttat
    42961 tttcttcatt gaaaaaagcc tttctttctg ctataatcgt ataaaatact tactttagga
    43021 gttcttatga aagttgttaa atttggaggt agttctcttg cctctgctag tcaattagaa
    43081 aaagttttaa acatcgtcaa aagcgattca gagcgtcgtt ttgtagtcgt ttctgcgcct
    43141 ggtaaacgca atgctgaaga tactaaggtt acggatgccc tgattaaata ctaccgcgac
    43201 tatgttgcgg gtaacgatat tagcaagagc caaagctgga ttatcgaccg ctatgctgct
    43261 atggttagtg aattgggact aaaaccagct gtgctagaaa aaatttctaa aagcattcac
    43321 gccttggcca ctcttcctat tgaagaaaat gaatttctct acgatacttt cctagcagcc
    43381 ggtgaaaata acaatgccaa attgattgct gcctacttta accaaaatgg tatcgatgca
    43441 cgctatatgc accctagaga agctgggatt gtggtcacaa gtgaacctgg tcacgctcgc
    43501 atcattccat caagttatga caagattgaa gaattgacaa acaccaatga agtccttgtc
    43561 attcctggtt tctttggtgt cactaaggaa aatcaaatct gtactttctc acgtggaggt
    43621 tctgatatta caggttctat cattgctgct ggtgtcaaag ctgacctcta tgaaaacttt
    43681 acggacgttg atggtatctt tgcagcccac cctggtatta tccaccaacc acactcgatt
    43741 cctgagttga cctaccgtga aatgcgcgag ttggcctatg caggcttctc agtccttcat
    43801 gacgaggctc ttcttcctgc ctaccgtgga aaaattcctc tggttatcaa gaataccaac
    43861 aaccctgacc atccaggtac tcgtatcgtt ctaaaacaca gtaatgatga atttccagtt
    43921 gtgggaattg ctggtgactc aggctttgtc agcattaaca tgtcgaaata cctcatgaac
    43981 cgtgaggttg gatttggccg caaggttctg caaatcctgg aagaacttaa catcggttgg
    44041 gaacatatgc caacaggtat cgacgatctt tctatcattc tccgttctcg ccaactaact
    44101 cccatcaagg aagaagaaat cctgcgtcag ttggttcaaa aggctaaagt agatcatgca
    44161 gaaatcgaac acgacctttc tatcattatg attgttggtg aaaaaatgaa gagccacatc
    44221 ggagtgactg ctactgcgac acgcgctcta tctgaaaaca aaatcaacat ccagatgatg
    44281 tctcaaggtt ctagtgaagt ttctattatg tttgttgtca ataaagacca agagaaagca
    44341 gcaattaaag ccctctacaa tgcctttttt ggagaaagta aggaagacta agcatggccc
    44401 aatcacttaa caaaacagta ctcctcagta cgacaggcac ttcctacctc tctatcgctg
    44461 ggaaagttgg gaaattcctt gtcggagatc aggctttgga attttaccca gatgtcaatg
    44521 tcgaacaatt tatccagatt ccttggagcc atatcaatca gattggagcc aatgtcactg
    44581 gatgcaaaat cagccgccac ttcgaagtct ttacagacaa aggaaaattc ctctttgctt
    44641 caaaagactc aggtgccatt ctcaaaattg cacgcgacaa attgggcaat gacaaggtcg
    44701 tcaaacttcc gaccctgatt cagacaatta gccaaaaatt taaaaatcta tttgcaaaaa
    44761 aatagaaact ttagtataat catagcaacg gataagtagg ttatcttctt ctttcagaaa
    44821 gtctgcgggt gctgcgagca gataggaggg ataggtgaaa ttctaccgtt agtaacaatt
    44881 acatacacaa tcaagtgcac acctgtgaag ttggatggaa ccgtggccct gccactccaa
    44941 cgttttgtca ggtgtgcttt tttcataaag gagttcttat gttagatatc aaacgtattc
    45001 gtacagattt tgaagctgtc gcagaaaaat tagctacacg tggtgtagat gctgctgtct
    45061 tgaatgaaat gaaagaaatc gatgctaaac gtcgtaacat cttggtcaag gttgaaactc
    45121 tcaaagcaga acgtaacaca gtttctgctg agattgccca agctaagcgc aacaaggaaa
    45181 atacagatga caagattgct gccatgcaaa atctatctgc tgaggttaaa gccttggatg
    45241 ctgaattggc agaaatcgat gctaaattga cagaatttac aacgactctt ccaaatatcc
    45301 cagctgacag cgttcctgtt ggggctgacg aagacgacaa tgtggaagtt cgccgttggg
    45361 gtactccacg cgagtttgac ttcgaaccta aagctcactg ggatctcggt gaagaccttg
    45421 gtatccttga ctgggaacgc ggtggtaagg taacaggcgc tcgcttcctc ttctataaag
    45481 gcctcggtgc tcgtttggaa cgtgctatct acaactttat gttggatgaa catggaaaag
    45541 aaggctatac tgaagtcatc acaccttaca tagtcaacca tgattctatg tttggtactg
    45601 gtcagtatcc aaaatttaag gaagatactt ttgaactcag cgataccaac tttgtcttga
    45661 ttccaactgc tgaagttcct ctggcaaact actaccgtga tgaaatctta gacggcaaag
    45721 atcttccaat ctacttcact gctatgagtc cgtcattccg ttctgaggct ggttctgccg
    45781 gtcgtgatac gcgtggcttg atccgtttgc accaattcca caaggttgaa atggtcaaat
    45841 ttgccaaacc agaagaatct tacgaagaat tggaaaaaat gacagccaac gctgaaaaca
    45901 ttcttcaaaa actcaacctt ccataccgtg tcgttgctct ctctactgga gatatgggct
    45961 tctcagctgc gaagacttac gacttggaag tgtggattcc agcacaaaac aattaccgtg
    46021 aaatctcaag ctgttcaaac acagaagatt tccaagcccg tcgtgcccaa atccgttacc
    46081 gtgatgaagc agatggcaag gtgaaactcc ttcatacctt gaacggttct ggacttgcag
    46141 ttggacgtac agtggctgca attcttgaaa attaccaaaa tgaagatggt tctgtgacca
    46201 tcccagaagc acttcgtcca tacatgggtg gagctgaagt catcaaacca taaaaaataa
    46261 ggtttagcta tttctagcta gacctttttt cgtaaccaaa tcagataagc acctagtaca
    46321 aagaataaaa tagttaggca tataatggtt tcagccaata ccaggtaatc cagaaatgga
    46381 agtttcaaaa ttccctgagc catcttgagc gaggtcgctg tgataatggt tgggaaggtg
    46441 agggctgaga aggctggttg aaaaccttgt tttaaaatgt tgggcagacg agttaaaaca
    46501 aagaaaaaga aggattgaga agccaaaatc atgacaatca agacccaatt cggcaggctg
    46561 gttcctccta ctcgaactag agaagccaag agtagagaga aaggagcaca gtagattcct
    46621 tcttgtccaa gcaaggctag tgggagtgga tgtttcttta aatcgctata aataagggga
    46681 tagagataga aggtcaagag aaaaccaaaa ctcaaggtcg cataggcaat ttcgataata
    46741 cctaccagag gataggtcaa ggcagccact gctatcccca catagagaac cgtccaactt
    46801 ggagtggcat gaaccctccg ccctgaacaa gcaaacttga tggtaaaacc agcaatcaag
    46861 gtcaaatcca agagaaatga aaaccaccaa atcccttgtg ctaccaaagg aagataagag
    46921 aatacgcgaa agacataggt cgataaaatc atcccagcca taggaaaggt tgccattcct
    46981 gacaaaagag ggggcttggt caattcttgc ttggtttctt tccaattaaa gagatgcaga
    47041 attagaaagt aaatccataa aaccaaacca gtcagactaa aaagatggga tagaaccggc
    47101 aacgtatcta aaataagatt tccagctcct gccaaaccta gcaaacaacc tgaaaatact
    47161 aaggggagtt ttttcatcct aacctccaat aatcatgtta gtttcagtat aacataaaag
    47221 cgcttaaatg atgatttaaa aaaacgaagt ccgattattt cagacttcat tttactcaga
    47281 tatgaattag gcataaggtt gcaattctgg attaattggt gtattagcta agttgttggc
    47341 atagttacag aggattgcta ggctgacacc aaaaaccaca tccaaggcat tttgttgagt
    47401 gtagccagct tctaaaaact cagacaaggc ttcatctcct acacgaccct tggtattgat
    47461 aactgccaag gtaaacttag ctagggtatc caatttagga tctgtttcaa ttggagtacg
    47521 attgcgaaga gcttgaatca agtcatcatt catctggatt tgtttgatgg aaaaggctgt
    47581 gtgacctgcg acacagaagg cacaaccatt ggtcacggct gccgtgattt gcaccacttc
    47641 acgctcaacg ggtgtcaggc tgttgcgacg gtggatagat gagacaattt ggtaggcttc
    47701 taaaacagtc ggggcattgg ccaagagacc gattaggttg ggaatatagc cattgttgtc
    47761 tttttctact gtttcaagaa tttctttcac ttctgctggt gctgactcta ctgtatggat
    47821 agtaaatgtt gtcataagat acctcttttc ttattattga cactaatatt attggaaaat
    47881 cttataaaat cctgattcct aagtttatct aagataaagc tttattctct cataagattt
    47941 tcgttgttat attagtttat cacacttcca atcacttgca taatatatat tatatatcag
    48001 gctgataaaa attatttata ggcaaaaaaa tcacacgagc tgtgtgattc cattatttgt
    48061 caaaatactt tttagtttca gcaataacga cttgcgacaa gaccaagagg gcaatcaagt
    48121 ttggcagagc catcaaggcg ttaacgatat ctgcgataat ccagaccata tccaactcga
    48181 taaatcctcc taacaagacc atgagcacaa aaaccacacg gtagagccag ataaagcgaa
    48241 ccccaaagag gaactcaaaa cagcgttctc cgtaatagtt ccaacctaga atcgttgtaa
    48301 aggcaaaaag cacaaggaag atggtcaaga gggcaggccc aaagtgtgaa aagactgttg
    48361 agaaagctga ctgagtcaag gcaaccccat tcaagtcacc actccaaact ccagttacca
    48421 agatggtcaa accagttaga gtacaaatga tgagggtatc aataaaggtt cctgtcatgg
    48481 aaatcaaacc ttgctctact ggttcatttg tcttggcagc tgcagctgca ataggagcag
    48541 aacccagacc agattcgttt gagaacacac cacgcgccac accattttga atagccatcc
    48601 gaacgctagc accagcaaat ccacctaccg cagcaagggg actaaaagct gaggtaaaga
    48661 ctaaagcgat tgtgccaggg atttttccga tattaaagaa aataactata agagttccta
    48721 agatataaat gatggtcata aaaggaacaa cagtagttga aaccttagaa atagacttga
    48781 gtccaccaaa gactgcaatc gctacaaaga cagacaagac gagagctgtg atgactggcg
    48841 aaatcgtcgt tgtattttgg atagattctg taatcgagtt gacttgggtg aaggttccga
    48901 ttcccaagag agcaaccaat actcctgcta ctgcaaacaa aacagcaagt ggtcgccact
    48961 tttctcccat ccctagaagg atatagtgca tgggacctcc cgctactgca ccatggtcgt
    49021 ccttggtgcg gtatttgatg gccaagagtc cttccgcata cttggtagcc attccaaaga
    49081 aagccgccat ccacatccaa aatagagctc ctggtccacc aaccttgata gccgtcgcaa
    49141 ctcctatgat atttcctgtt ccaacagttg atgccaaggc tgtacacaga gctgcaaaac
    49201 tggatacatc accatgtccc ttatcctgga taaaaataag ctgaaaggcc ttgggcagac
    49261 gcaaaacctg caagagtcct agccgcatgg ttaggtaaat ccctgttccg accaataaaa
    49321 tcaagagggg cggtccccaa gcaaaatcat cgattgattt aagcaattct aacatttcct
    49381 tctcctatcg tttcaacccc aaaagaaaga gcacatgcaa gatacatgta ctctggaatg
    49441 cttagataaa tgctaaaaag cggtctatcc tagctctgtc cttttacctg agagtttgag
    49501 cagttgcctg ccttgcccct tcggtgcctt tacggtctct ccagagttcc gtccatttac
    49561 agtcatggaa aatcaaacga ttccccactt ctattaaact tcattcggtg ttggtattta
    49621 attgattcta attttacaaa aaatgttggc ttttgtcaat gtgtttatta gtaaaaatta
    49681 gttcaacagt ttttacttta taaagtccag aatactgcta tcctttaaaa gtgacaatag
    49741 tcgcaccact gcctccagca ttttgtgggg catagccgaa actcttgaca tgtttgtttc
    49801 tttgcaagta tttggtaact ccttcacgga tgactcctgt tccgatacca tggatgatat
    49861 caacttgagc catattgtta agcaaggctt ggtcgatgaa ggtatctagc tcattcatgg
    49921 cttcttcata gcgcttgcct cgaagatcca gtctagcttg aggtcctcgc ccagaagttc
    49981 gtttcacaac attgacctgt ttcttcttga ctggtttttc ttgctgggct tgaacaagat
    50041 caaactcttt ctcttccaag gtcatcttaa tcaagccaac ttgggcttcc cagcggccgt
    50101 ccttgagttg actggtcaag gtaccacgct gaccataact gagaaccacg atatcatctc
    50161 ccacctttgg agctcgtttt ttcttggcct tttgaaggac cttgttttta gacaagtcca
    50221 ctttttcagg agccaatttt ttcaacttgg ccttggcttc aatgatttcg tggggcttga
    50281 gttgggattt actgtggaga tttttgagaa tctggtcact ttcacttagg gccatatcca
    50341 caatctcagc agcctgttca cgcgccttgt taagctcggt ttccttttca cgattaagct
    50401 cgttgtagag tttttttagc gcacggttca tcttgagatt ttcttgctcc acctcacgga
    50461 tattgtccaa acgtttgcgg ctttccagcg tctgctcttc taattgctca atgatacgat
    50521 tgacgtcatt gtcctgatcg atctgctgac tggcatctcc tacgataact tcagataggc
    50581 ctagacgttt ggcaatttca aaggcattac ttcggccagg aacaccctgc ataaagcgat
    50641 aggtcgggcg aagagttgca gtatcaaact ccatactggc attttgcaca aaggctgtct
    50701 caataccgta ggccttgagt tctggatagt gggtcgtcgc catggtcttg atttgacgca
    50761 ggcgaaggtc ctccagaata gccatggcaa gggctgctcc ctcttgggga tcagtaccag
    50821 cccccaactc atccaaaagt aagagtgaat gttggttgac cttgccaaga atatccacga
    50881 tattggtcat atggctagag aaggtagaca agctctgctc aatagactgc tcatctccaa
    50941 tatcagcaaa gatttcttca aaaataccaa cacgacttcc cttgtctgct aaaatcggca
    51001 atcctgactg ggccatgacc tgtgtcaagc ccagagtttt gagcatgatg gtcttcccac
    51061 ctgtattggg acctgtaatg acaatagctg ttaaatcttg accaaaatag acatcatttg
    51121 cgacggcatt tttgaccaaa ggatggcaga catggagcag ttgaatctct tgattttctg
    51181 acagctgagg cacgactgct tgtctttctt ggataaatcg aaccttggca cgaatcaagt
    51241 ccagatgacc gataatccaa gcgtcattag caatctcagc cgcatgaggg cggacacgct
    51301 cagaaatttc ttggagaatg cgaagcattt catagcgctc atctgctcgc agactagcaa
    51361 tttcttcgct cagtttgact acctcacgtg gttcgatata gacggtgttt ccactagcag
    51421 aaatatcatg aacgacacct gcaatcttat tgcggtaggt gtttttgact ggtaaaacct
    51481 gacggccatt tctgctagca acaattcctt ccgtcaacat ctgcgctttt tgcttgagta
    51541 agtcttgtaa aacatcgcgc acctgactct cgctatcatg tatttttcga cggattcgcg
    51601 ccaattcttc actggcaaaa ttttcaatga aacccgcatc attaaaggcc tgaagatttc
    51661 cttgtaattg cggaaaatca tgtaatttct caaaccaaag ggctaattct tccaagctga
    51721 cattttccag attggcgtaa aaattttgaa gttctcggct ggcaagaagc acgcgtttca
    51781 agagtaggaa ctcctcgata ttgagatccg ctcccatctc caacctcttg cagactcctg
    51841 caatttcctt agttgagaga atagtaaaat gcggttgctc gacgaaaaga gcctgcattt
    51901 ctttcatctc agcaaaagcc tgtttgattt tatctgcttt ggcagtcgga gccagctgtc
    51961 tcaattgctc caagccctgc tcggtcaaca aatgaggctc aaacaaggcc ttgaccttat
    52021 cgaactctaa tgtttctaat attttcttat tcatctttat ttccttgtct ttgaatgtct
    52081 aggtgtggta gctttttaca ttctgataga ttcgagtcaa atctgtaaac aaagggctag
    52141 gaaaactcct gcccttttta tccgattaaa tttgtcaccc agatttgttt gagccaactg
    52201 gttgttaccg gtatgctctg gatgatgtgt tttgcgacga tactcttttc aagaggattt
    52261 tgtataactg ccatggggat ggtcgccaag attgtcaagg ccatttgcaa gacaaataag
    52321 gtcaccaaca tggacaagat acctgctgaa acttggaaca acttaccacc cagttttttg
    52381 ctaggaatca agtgtaagag aagaccaagt aaacgaccaa tgctatagac aatcccaaat
    52441 acaagcaagt agccgatacc tgcataaaag accttatcca gctgaaagag ttgatccgat
    52501 gggaaaaaga aagtcccctg accttcctgc gaatttgcat aagggagcaa taaatggaat
    52561 tgctctccaa gccccttata aaactggcca gccataaaag ccgatgccat ggctgaaatc
    52621 aggtaataaa cctgtaagag caggcctctc cgatagccga tataaaatcc ccaaaccaag
    52681 accaatagaa gaaggaatga aatcataagg aatcctcaat cttgctctgt tcttgcttac
    52741 aagtcacaag cttgtgacgg agttcttcta gctcttgctc cttatcgtca aattcaatct
    52801 cacggctgag ctgagttgat aaacagttga ctgccaacaa aagagcgatt gtttcatcat
    52861 ctgcgctagg catttgttct ttaattgctt ggtatttttc tgtcgcaacc ttagcgattt
    52921 cctccataaa aaggttgtca tgttcgcttg tcaaggttaa cgattttttc ccgaatgtaa
    52981 atttgaatcg atttagattt gccataaaat tcacctcacg atattatacc aaaattcgct
    53041 aattttgtca gtttttacaa attttactgc ttttgtggta caatagaaac tatggcaagt
    53101 atcacactca caccaagcga aaaggatatt caggcttttc ttgaacacta tcaaaccagt
    53161 ctggctccta gcaagaatcc ctatatccgc tactttttga aactacctca agcaacggtt
    53221 tctatctata cttctggaaa aatcttgctt cagggtgaag gggctgaaaa atacgccagt
    53281 ttctttggct atcaagctgt agagcaaacc agcggacaaa atcttccttt aattgggaca
    53341 gatgaggtgg gaaatggttc ctactttggt gggcttgcag ttgtggctgc ctttgtcaca
    53401 cctgaccagc acgacttttt acgaaaactc ggtgtggggg attctaagac tctgaccgac
    53461 caaaagatcc gtcagattgc tcctattctc aaggaaaaaa ttcagcacca ggcactcctt
    53521 ctctcaccca gcaagtacaa cgaggtcatc ggagaccgct acaacgctgt ttcggttaag
    53581 gttgccctcc ataatcaggc tatctatctc ctccttcaaa aaggtgttca gcctgagaaa
    53641 attgtgattg atgcctttac cagtgctaaa aattatgaca agtacttggc acaagaggcc
    53701 aatcgtttca gcaattctat cagcttagaa gaaaaggctg agggcaaata cttggctgtc
    53761 gcagtttctt ctgtcattgc gcgtgatctc tttctggaaa atcttgaaaa tttgggacga
    53821 gaactgggtt atcagcttcc aagtggagct ggaacggctt ctgacaaggt ggctagccag
    53881 attttgcaag cctatggtat gcagggactc aacttctgcg ctaagctaca ctttaaaaat
    53941 actgaaaaag cgaaaaacgc ttagaaaggt aagttatgaa tttatttaaa aatttcttaa
    54001 aagagtgggg attattcctc ctgattctgt cattactagc tttgagccgt atcttttttt
    54061 ggagcaatgt tcgcgtagaa ggacattcca tggatccgac cctagcggat ggtgaaattc
    54121 tcttcgttgt aaaacacctt cctattgacc gttttgatat cgtggtggcc catgaggaag
    54181 atgggaataa ggacatcgtc aagcgcgtga ttggaatgcc tggcgacacc attcgttacg
    54241 aaaatgataa actctacatc aatgacaaag aaacggacga gccttatcta gcagactata
    54301 tcaaacgctt caaggatgac aaactccaaa gcacttactc aggcaagggc tttgaaggaa
    54361 ataaaggaac tttctttaga agtatcgctc aaaaagctca agccttcaca gttgatgtca
    54421 actacaacac caactttagc tttactgttc cagaaggaga ataccttctc ctcggagatg
    54481 accgcttggt ttcgagcgac agccgccacg taggtacctt caaagcaaaa gatatcacag
    54541 gggaagctaa attccgctta tggccaatca cccgtatcgg aacattttaa gaaacctaag
    54601 aggccgagaa tcaccaatct cagcctcttc ttctatcgtg agaaaatgat tggtaactat
    54661 ctaaacttac cagaacagaa acacctcaac tctcacctat tcatgcaaag gaattttatg
    54721 gaagtttatt tttcaggaac cattgaacgg attatttttg aaaatcccag caatttttat
    54781 cgcatcctcc tcctagaaat cgacgatacg gacgcagagg attttgatga ttttgaaatc
    54841 attgtcacag gaaccatggc tgatgtaatt gagggcgaag actatacttt ttgggggcaa
    54901 attgtccagc actccaagta tggagaacaa ctgcaaatca gtcgttatga tcgcgcaaaa
    54961 ccaactagta agggcttggt caagtacttt tcaagtagcc atttcaaggg gattggtctc
    55021 aagacagctc agaaaatcgt ggatacctat ggcgaaaata ccattgacga aattttgcaa
    55081 cacccagaaa agttagaagg catcgcagga ttctctgcca aaaatcgcga ggctttcgtc
    55141 tccactctcc gtctcaacta cggaacggag atggttttgt ccaaactagc caactacggc
    55201 attcccaaca aactagcctt tcagattcaa gacttttaca aggaagaaac ccttgatgtg
    55261 gttgaaaatt atccctacca gctggttgag gatatcaagg gtttgggctt tacaattgct
    55321 gaccaactag ctgaggaact aggcatcgaa agtcaggctc ctgaacgctt ccgcgccggt
    55381 ctagttcaca gtctttttca ggcctgtatg gaaacagggg acacctatgt tgaagcacgg
    55441 gatttgctgg aacaaaccct tactctcctt gagtcttccc gtcccgtgga actagacccc
    55501 agccaagttg cccaagagct ctcctacctg atcgaagaag acaaggttca gcagattgat
    55561 accaagatct ttgacaacag cctctttttc gctgaggaag gtatccgcag tcacttgatt
    55621 cgtatccttg aaaaaggaaa acagaagagc caagatttag aaactattca aaagcatatc
    55681 actactgtcg agcaagagct gggaattgag tatgataaca ttcaaaaaca ggctatctgt
    55741 gatgctatcc agaataaggt ctttatcctg acaggtggac ctggtactgg taagacaact
    55801 gttatcaatg ggatcatcgc tgtttacgcc ctgttagagg gacttgacct caggaagaaa
    55861 agcaatctgc ccattcttct tgctgctcca actggacgag ccgctcgccg catgaatgaa
    55921 ttgacaggtt tgcctagcgc gaccatacac cgccacttgg gaatgacagg tgacgatgat
    55981 accagtcatc tggaagatta cctagatgct gactttatca tcgtggatga attctctatg
    56041 gtagatactt ggctggccaa tcaactcttc tccaatatct cttctaacag taagatcctc
    56101 atcgtaggtg acagtgatca gctaccttct gtcagtcctg gacaggttct agcggatctg
    56161 cttcatattc ctttgattcc tcagactcgc ttggaaaaaa tttatcgaca aagcaaagaa
    56221 tcaaccatcg tcaccctagc tagtcagatt cgacagggca tcttgccagc tgatttcacc
    56281 caaaaaaaag ctgaccgttc ctactttgaa attgctagtg gccatattcc tgccaccatt
    56341 gaaaaaatct taggtgtcgc cctcagaaat ggtattcctg cccgtgatat ccaagttctg
    56401 gctcctatgt accgagggac ggcagggatt gatgctatca atcagctcat gcaagacctg
    56461 ctcaatcccc cacaaaaaga tcaactcagt tttgaagctc ctcagtgcca ctatcgtaag
    56521 agagacaagg tcattcattt ggttaacgat gctgaaatca atgtctttaa tggggattta
    56581 ggagctatca cagacctgat tcctggtaaa tacaccgaat cgaaacaaga cgagattgtc
    56641 attgattttg atggtaatga agtctcttac ccccgtaacg aatggtacaa gattcgcttg
    56701 gcctatgcca tgagtattca taagtctcag ggaagtgagt tcccagttgt catcctaccg
    56761 attactagtg ctagccgacg tatgctggag cgaaatctca tctacacagc cattacacgt
    56821 gccaaaagca aactcatctt actaggcgaa ttacaagcct tcgactatgc tacccaacac
    56881 atcggaactg cccgaaaaac ctatctgatt gaacgcttca gtgatctact ggagaatgtt
    56941 gaagaaaagc aacaagctgt ctctgaaaca gtcacatcaa gtgcctctga acaatcctac
    57001 atcctaaccg aagaaaactg ggaccgcatc ccagccatga ttgggattac agacacagac
    57061 ctcaaagaga tttttggaaa atagtgcatc agaaaaccca ccaattcagg tgggttttct
    57121 gtttattaag attattttac tgttgctgtg cttgtgatca attcaacagc ttttttgata
    57181 gtgatatcat gtttcaacat gtcagctgaa agcaagtttt gaacttgtgc aacttccatg
    57241 ttgtagtctg ctgccaattg ctcaacttct ttttggattt cttcttctga agcatcaaat
    57301 ccttcagctt tggcaactgc ttcgataaca aggttagtct tagtacgtga ctcagcttct
    57361 gcttggtatt ggttgtgaag gtcttcttga gtagttccag tgatttggaa gtacatgtca
    57421 gggttgatcc cttgacgttg caaattccca aggaattcat ttactgaacg gtgaacttct
    57481 tcatggatca tttcttctgg aagttctacg atttcagcat tttctacagc tgtatcaatt
    57541 gctgcacctt caactgcatc tttgtaagct tcttctttag cagcagccaa ttctttgcgg
    57601 tatttttctt tcaagtcagc aagtgtttca acttcttcat caatgtcttt tgcaagttca
    57661 tcgtcaagag ctggaacttc tttagctttt acttcgtgga tagttgtcac gaatttagct
    57721 tctttacctg caaggtcttc tgcttggtag tcttctggga atgttacgat aacatcaacg
    57781 gtttcgccag ctgagtgacc taccaattgg tcttcgaaac cagggatgaa ttgacctgaa
    57841 ccaagtccaa gtgagaagtt ttcacctttt ccgccgtcaa attcaacacc gtcgatagaa
    57901 ccaacgaagt cgatcacaac agtgtcgccg ttttcagcag cagcttcctt gataaccaat
    57961 tcagccaggt tgttgcgttc gcgttcgata cgctcttcaa catcagcgtc agttacttct
    58021 ttttctacat caactgatac ttcaaggttt ttgtagtcac ccaattttac ttcaggtttt
    58081 gtaacgactt cagcagcgat aacccagtct tgaccttttt ccattgaagt tacgtcaatt
    58141 tttggttggg caaccacttc aagaccagct tcttttacag ctgcttcata agcgtttggc
    58201 aaaagagcgt tcataacgtc ttggtaaagt gattcttcac caaatttttt atcgaagata
    58261 ggacgtggaa ggtgaccttt acggaaacct ggaacattaa gagatttctt cactgacttg
    58321 aagacacggt ccaattctgg tttgatttgg tcttgagaga tagtgaaagt caagacacca
    58381 cggtttgttt ctttgttttc aaatgataca gacattctgt catttctcct taaaattttt
    58441 taaatacagt ctattataac attttctata aataaaatct agactaatgc agccaattat
    58501 agacaacaag cctttttcct aactaaaaca ctcataaagt atagacaatt ttagactact
    58561 ttggatatct tttggttagt cattttccaa aactaattta tctaattttt cagttatatt
    58621 tgacttcatc ttctcagtaa catgagtata aacacttaaa atctttgttt cattagtata
    58681 atctacacga tccattatcg ctgttatagg tacttccaat tcagcaagca aacttatatg
    58741 cgaatatcta aaaacatgag cagtcaatac aaaatcatct ttcttaattt cacttttcct
    58801 aaaactgttt ttcaaaaagt aattgaaaca agttatcatt aagggagaac cattatttgt
    58861 aaatatataa tcaccttctt ctaaaagaag atattctttt aaaatttcta acactctatc
    58921 actaatacca attactctat atgaagctaa acttttcgga ctatccaaaa atacttcgtt
    58981 attggacgat tacattatag taaaacgaaa taagaacagg acaaatcgat caggacagtc
    59041 aaatcaattt ctaacaatgt tttagaagta gaggtgtact attatagttt caatctacta
    59101 tacaagacga aattgaagaa atctttccat tataaaacgc atattatcaa ggtttttaaa
    59161 cacctaataa tatgcgtttt ttcctatttt aaagactttt atccacctat tatacaaagt
    59221 taagtatcca tcacagttta caattagcct tcattaccta acccattcac catccttcaa
    59281 gagagtaacc tttaagaacc gaataaataa atggcaaatt tcgttcattt aatttaactg
    59341 cactgttaat ttgattagct ccatctccta aagtatgcac tcctactaca cggtgactag
    59401 catcataaac tgtagatcca ctagacccct ctaaagtatc aacttggtaa tccaagaaca
    59461 tgccatcatc acttaaaact tgttttttat ctgtatacat ttgatgaatt ttaaaattat
    59521 atgatagata gcctgtgata gtcacagtta ttcctgtcaa atttttttga ctagtaggaa
    59581 gacccaaagt ccctaatttt gcaccaatgg gctcttctag aattaataaa gccaagtcat
    59641 attcccttgc atccttagaa tttaaatttc taaattcctt caaataacga acttccttta
    59701 ctttgatctt tccaaatagt tcttgacttg gactaacagc cggaagaaca taaatatcat
    59761 ccgcttcttt cccatagtca tgtctgtagt agttgtgagc cgctgtaatt aacacattat
    59821 ctttaataaa attcgcactt cccctccctt ctacattcat tccatcggct actccataat
    59881 acttagataa aaccatagct gaagtcgaat acggatactg taaagtatta tcaattttaa
    59941 tcaaatcatc attaccgata atacttctga ttgcttttgg tagtatgaac catacgttgg
    60001 tgaaatctca gataatgaag aatcattaga ctctggacct ttttctagtg tctcacttac
    60061 ctcatattct tcacctgtac tagaaataac actcaaagca gatactgtcg ataactggct
    60121 agccaataaa gtactcgcaa taattgaaat acccaatttt ttataaacag ttttcttcat
    60181 tattgtatcc tcctaatgta attatagcgt actattctaa atttcttaat ctactataga
    60241 atcaagaaat ctaccacctt ctttaaatac cctccattat cacataaaca ggtaaacttt
    60301 tcaattaatg actgcgcttt tcaatcacgc tagaggtact tgcttgcttc tttgatacta
    60361 agttcagcca ttctttcctt gtttttctca ataaagcatg ttacccaagt gggattcgtt
    60421 ttggagtagt ctcgcagagt ccagccaatg gctttattga taaaaaattc tgtttggttc
    60481 aagttatgaa gtagaatctt ttccattaat tgagtattgg tcttctcttt tcttaacaac
    60541 tggtggtcaa tagcgacacg tctcagccag atattatctg ataggctcca ttttatactc
    60601 aatgaaaatc aaagagcaaa ctaggaagct agccgcagat tgctcaaaac actgttttgg
    60661 ggttgcagat agagctgacg tggtttgaag agattttcga agagtattaa gattatttct
    60721 tctagttcag agtgttcata caccaaactc cctactactc gatctaggat atctaccgtg
    60781 tcccaccagg attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga
    60841 taagactgca ttgctttcaa atagttagca gccacatatt ggtattctct aggatccttt
    60901 tcccagcaag tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctggaaaa
    60961 tatttttata gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc
    61021 gcatataggc ttccatggac cttgcttttt tagagtcttt tgctgcttct agctcctcaa
    61081 gtaaatctgc taaactcatc taaaactcct cttgccccac caaatggtgc tgaaaggcat
    61141 agacagccgc ctgggtacga tcgctgactt caagtttggc aagaatattg gacacgtggg
    61201 tcttgaccgt cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct
    61261 tggcgatgag ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat
    61321 gattgcggtg gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag
    61381 ctaccttact gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt
    61441 tggcaccagc atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca
    61501 aaatcttggc ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc ccattcatct
    61561 caggcatgac aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc
    61621 cttgagaccc gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc
    61681 ttttcaagcc caatcggacc atttcatggt catctactag taaaattttc atctttactc
    61741 ctttatcatt ccttatctaa caggggaata cggatatcaa ccgccagccc ttgcttggga
    61801 gctgtcaaga gttgaactgt tccagccata tcttcaaccc gctccttgat atttcgcagt
    61861 ccataactca agtcgtctaa gctccctaac tggaaaccaa tcccattgtc caccaccttc
    61921 agttgcaatt caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg
    61981 cggagggtat tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta
    62041 ggcaatttcg tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct
    62101 tttaagagaa tttgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa
    62161 tgcaagagca aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc
    62221 aactggatct gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa
    62281 atcatgtggg ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc
    62341 ttccgttcct tctcgatgat ttcctcttcc tgagcaaggc tatgattttc agctttttga
    62401 agagcttctg tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct
    62461 ggatctgcaa cctgaaccac ttcttgccct gccaataaac gcttgagatt agcctgcatt
    62521 tttcttagag aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggttatggac
    62581 atgctgaaaa ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtgcaaaaag
    62641 atagaccagt caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaacagg
    62701 aaggaggtga gagcaataat gacataggct tgttttttca tcctctaacc acctccacat
    62761 caccaatcat agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg
    62821 tttcttgatg atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat
    62881 ccccatagag acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg
    62941 tcgttcctac catctttctg aggataatga cattgtcatg attggttaag atgaccctct
    63001 ccagatgaat agtgtccttg cccatgaagc gaaagagatt gatatcatcg aattggcaag
    63061 tctggtagct tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg
    63121 tcacgacctc ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa
    63181 gaagaaagag gctatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca
    63241 taacgatgaa aaagaagaga atggttgccg ctactaaaag aagattattt ccctctttac
    63301 cagtgtagta gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat
    63361 gctctgatac catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga
    63421 ttttaaattt tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc
    63481 acctcagtct gaggatggaa aaaaggcgct ggttacgcct ttttcatctg atcctttgct
    63541 tcttttaatt ttccataaag aagatagtct actttttgta gatctgctat ggtggcacag
    63601 ttaagggaac acataatcaa gcgtaggtct gctttccagc cttggacaat gccaatcact
    63661 tcttcaactg tgtaggtttc aaccaattcc agaacggttc gtgacaatcc cacagactta
    63721 gcaccaaaaa ccaagcactt aatcatatcc agcggattcc gaacccctcc actaaccaag
    63781 agttcgacct tatctttcca ttcttgggca ttgagaaggg cctgcatggt agactgaccc
    63841 cattgattga ggtaatcacg ctggccacta cgacggtttt cgatataggc aaagctggtg
    63901 ccaccacgac ccgataggtc cactgtacga acaccgaatt cataggctct ttcgattgtc
    63961 ttggcatcca ttccaaagcc cacttccttg aggacaatag gaacgggaat ttgctcgcta
    64021 taatctgcta gatgcgattg ccagcttcta aacttccttt ctccctcggg catgagtaat
    64081 tcctgcatga cattgacatg cacttgcaat agaacaggat tcatctcttc tacagtctga
    64141 agccctaact cgacaggctt gtccaatcca atattggttc caaggaggag attgggatga
    64201 ctagacttga cagaaaaaga atcatccgtt ggatttttga gggctgcgct ataagaaccc
    64261 gttacaaata aaataccaca ggattccgcc acctgagcca gcttttgatt gatttctctt
    64321 cccttattac ttccaccagt catggcattg atataaaaag gaaagtccca ctttcgacca
    64381 gcaaactctg tcgaaagatc gatttcatcc agattgtaaa gaggcaagga agaatgaatc
    64441 agctccacct catcaaagct attataggaa cttttctgct caagggcata gaggatatgc
    64501 tcgtccttac gatttgtcgt catgtcctat cctttcttga tataagagct caatccccag
    64561 atcggcccaa cgatttttta aggtttcggt tgattgcgca tcaaaactca aggcgatgcc
    64621 acagtcacca ccaccagcac cactactctt ggcaacggcc tgcaaatctt gactggcttc
    64681 tttcaactgt ctaagcaaag gcgtgtaaat atctgtactc aagccttcta aaagcttgct
    64741 ggctacttct acttgctcga taactttttc ggctttcccc tgctccaagg cttcgaccaa
    64801 agaaaccacc gtttcttttg aggaacttaa aaaattttga ttgatatttt gcttgatttg
    64861 ctggaccatg tgactcgata cagccacttc cttggtccat cccactaaga aatcacattc
    64921 taaagttggt ttcacttgtg agataaaaaa tccccaatca cgctccagaa ctgtcgccaa
    64981 gttttcttct tctaaccaag cagccacctt ctggcgatca aatgactggt agagaaccaa
    65041 atcctctgcc acaatacagg caaggtcgcc catggaacca ttgtctcctc gcttgagcaa
    65101 gacagcgcta gtcagcttga acaagagatt ctgatcaacc gaaagattat agagagccag
    65161 taaagccttg acaaccaaga caacgacgct gccactagaa cctagaccaa actttttccc
    65221 ttctcgttcc attttgccac agatttttag ggaaaaaggt cttaaattct gaccgcgaac
    65281 agcgaggaag tctcccatca aagcaatcgt ttcttgaatc aagctgtagt caggattagg
    65341 ccttaagtcc actgcgaaat caaacatatc tgaatagata cggtagctgt cagaaaaagc
    65401 aatttcagcc ctcatataga tgggaatatc ctttatcaaa gctaactgcc ctggctctaa
    65461 aatagcatat tcacctgccc aatagagttt tccgcaagtt ttaacagcaa tcatcttgac
    65521 tcaaatcctt tgtttttgac acaatcaagc gataacgctg accgaaaatt tctgataaat
    65581 gctccaagtc tttctcctga cagaagacct taacattggg accagcatcc atggtaaagt
    65641 agcaggcctc tcctttctca cgaagctggc gaacaaagtc catagcctca taagaggcat
    65701 ccgtcagata agaaaaggct ggactagcag tctttgtcgt agcatgcata gccagggcat
    65761 ttttctccgt taattctcca atcttggcaa aatcattttc cttgagataa atcagcatat
    65821 cctgatagtc cttctcagac tgacgaaccc agtcgtcgaa agtcgtcgag gtttccacac
    65881 aaagtttcat cccgtcacgg ctagagattg gttttttctt gtcctctagc accaacataa
    65941 tcatagctag tttcaagtct gtctctacag ggtaaatttc tccactatcc ttatcccagg
    66001 ctcctagtgg tccataaaaa ctccgagaag aagagcctga ggcaaacttg gcttcctgcg
    66061 ctaactgact tctatccaat ccaagcttga aataagcatt acaagccttg accagggcgg
    66121 acaaaccact agaacttgag gacaggcccg ctgccgtagg catattgttt tgagtatcga
    66181 tacggacaaa gccctcacca gctggacgat aacggtcaat aatcttactc atcttggcat
    66241 gctcgacctc attttgtagc tgaccattga tgtaaaattc gtcagctgtt acattggctg
    66301 gtaaaggcga caaggtcgtc tctgtataca tattttccaa agttagagaa atactgctag
    66361 tagcaggcac catctctttt tcttttttct ttccccaata tttgataata gcaatatttg
    66421 cgtaggaacg tactgttaca ggctctctat ccatgtctga acagctcctt tctcttctaa
    66481 tctttctgct agttcttgtg cgtgtgtcaa attggttacc aaggctatga tacaacctcc
    66541 tagcccacca ccgctcatct tggcacccag agcaccatgg ctaagagtcg tttcaaccaa
    66601 aaagtctgcc tcagggctac tgactccaat ttcttttaaa tgtaaatgcg cttgactgag
    66661 gatttgtccc agtccttcag catctttttg tgaaatcgca acttctgctt gctgggttaa
    66721 ttctcccaag gcatgcaaaa acggtagggc atccttgccc ttattttgaa ccacttggat
    66781 ggcttcacga gtatgaccat aaacacccgt atcggcaatc accaaatagg cggataaatc
    66841 catctcaagt tctgtaaatc ctacgttctt gataaagcga ataggttggt cactgagaca
    66901 ggtcttagca tccaaaccac taggattcat atgggcaatc atttcagctc gattgaccaa
    66961 gatttctagt acatcatgag gcagatcagc ctgatagtag tcaaataccg cacgaatggc
    67021 cgctatgctg atagccgctg acgaacccat cccccgtttc tcagggatag ccgagtcaat
    67081 ctcacaacga atgcaggctt ctgtgatatc caaatactcc agtgaggcat aaaccgccat
    67141 ggacaaggta tcctcctcat aaaggcgcca aggactctct gcaggaacta ccttacaggt
    67201 cacctccacc tccaaaagag gcagggaaat ggcaggataa ccgtaaacga ccgcatgttc
    67261 ccctattaaa attatcttac tatgtgcctg accgacacca actttttttg tcattttttc
    67321 cttttactag acgaaaaaac gtcttatttt tcatacaagt attaattctt tcctatctat
    67381 tttattatat tttcacaaaa aaagcgattg tttccattca caatcgcttc tttcattacc
    67441 gaacccattc accattataa ttgacagaat agccatctac aatcgtattc actgccaagg
    67501 cacctgagct ataagcgtag taccatctgc cattgacctg gaaccaacct gtcgtcatag
    67561 aacgatgaaa gaaactccat accattaagt aaagaggaaa gtcatgaggg agcatgcgtc
    67621 attgacaacc tattttagtg acgtacaaag tttcattaac aagtactcgt ttcggccatt
    67681 tataggtgcg gtgtttgcag aaatagggtt caatcttcgc ccattcttga tcgtttaaat
    67741 cagtatcata tgctttgcgt gtcataactc tagtttaaca tttttttgtg aatacaggtt
    67801 ctaaataatc gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg
    67861 aaacttatgc acttaatttg acaactcaat atgtaaaaat atatactata
//
LOCUS       DAVBOM010000003        67652 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBOM010000003 DAVBOM010000000
VERSION     DAVBOM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.003"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VQ878_000139"
     CDS             complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VQ878_000139"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3094563.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1419..2195
                     /locus_tag="VQ878_000140"
     CDS             1419..2195
                     /locus_tag="VQ878_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET3094564.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2205..2981
                     /gene="recX"
                     /locus_tag="VQ878_000141"
     CDS             2205..2981
                     /gene="recX"
                     /locus_tag="VQ878_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET3094565.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            3070..3603
                     /locus_tag="VQ878_000142"
     CDS             3070..3603
                     /locus_tag="VQ878_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET3094566.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(4044..4799)
                     /locus_tag="VQ878_000143"
                     /pseudo
     CDS             complement(4044..4799)
                     /locus_tag="VQ878_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(4937..6559)
                     /gene="groL"
                     /locus_tag="VQ878_000144"
     CDS             complement(4937..6559)
                     /gene="groL"
                     /locus_tag="VQ878_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET3094567.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(6575..6859)
                     /gene="groES"
                     /locus_tag="VQ878_000145"
     CDS             complement(6575..6859)
                     /gene="groES"
                     /locus_tag="VQ878_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET3094568.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(7129..7524)
                     /locus_tag="VQ878_000146"
     CDS             complement(7129..7524)
                     /locus_tag="VQ878_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET3094569.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(7602..8363)
                     /locus_tag="VQ878_000147"
     CDS             complement(7602..8363)
                     /locus_tag="VQ878_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3094570.1"
                     /translation="MVKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(8396..9022)
                     /locus_tag="VQ878_000148"
     CDS             complement(8396..9022)
                     /locus_tag="VQ878_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET3094571.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(9038..9355)
                     /locus_tag="VQ878_000149"
     CDS             complement(9038..9355)
                     /locus_tag="VQ878_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET3094572.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(9352..9651)
                     /locus_tag="VQ878_000150"
     CDS             complement(9352..9651)
                     /locus_tag="VQ878_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET3094573.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(9936..10127)
                     /locus_tag="VQ878_000151"
     CDS             complement(9936..10127)
                     /locus_tag="VQ878_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET3094574.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(10288..10962)
                     /locus_tag="VQ878_000152"
     CDS             complement(10288..10962)
                     /locus_tag="VQ878_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094575.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            complement(10967..11413)
                     /locus_tag="VQ878_000153"
     CDS             complement(10967..11413)
                     /locus_tag="VQ878_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3094576.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(11527..12030)
                     /locus_tag="VQ878_000154"
     CDS             complement(11527..12030)
                     /locus_tag="VQ878_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3094577.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(12027..12389)
                     /locus_tag="VQ878_000155"
     CDS             complement(12027..12389)
                     /locus_tag="VQ878_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET3094578.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLTCLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(12515..14314)
                     /locus_tag="VQ878_000156"
                     /pseudo
     CDS             complement(12515..14314)
                     /locus_tag="VQ878_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(14331..14800)
                     /locus_tag="VQ878_000157"
                     /pseudo
     CDS             complement(14331..14800)
                     /locus_tag="VQ878_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(14924..15640)
                     /locus_tag="VQ878_000158"
     CDS             complement(14924..15640)
                     /locus_tag="VQ878_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3094579.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(16521..17936)
                     /gene="ply"
                     /locus_tag="VQ878_000159"
     CDS             complement(16521..17936)
                     /gene="ply"
                     /locus_tag="VQ878_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET3094580.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(17947..18279)
                     /locus_tag="VQ878_000160"
     CDS             complement(17947..18279)
                     /locus_tag="VQ878_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094581.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(18350..18958)
                     /locus_tag="VQ878_000161"
     CDS             complement(18350..18958)
                     /locus_tag="VQ878_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094582.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(18971..19429)
                     /locus_tag="VQ878_000162"
     CDS             complement(18971..19429)
                     /locus_tag="VQ878_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET3094583.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            19554..19953
                     /locus_tag="VQ878_000163"
                     /pseudo
     CDS             19554..19953
                     /locus_tag="VQ878_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20718..20978)
                     /locus_tag="VQ878_000164"
     CDS             complement(20718..20978)
                     /locus_tag="VQ878_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094584.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(21037..21588)
                     /locus_tag="VQ878_000165"
     CDS             complement(21037..21588)
                     /locus_tag="VQ878_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094585.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(21578..21775)
                     /locus_tag="VQ878_000166"
     CDS             complement(21578..21775)
                     /locus_tag="VQ878_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094586.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(21779..22363)
                     /locus_tag="VQ878_000167"
     CDS             complement(21779..22363)
                     /locus_tag="VQ878_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094587.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKKFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELIPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(22761..23186)
                     /locus_tag="VQ878_000168"
     CDS             complement(22761..23186)
                     /locus_tag="VQ878_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094588.1"
                     /translation="MTSRVFIDADCISVFLWVGIEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(23315..23674)
                     /locus_tag="VQ878_000169"
     CDS             complement(23315..23674)
                     /locus_tag="VQ878_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094589.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(23720..23926)
                     /locus_tag="VQ878_000170"
     CDS             complement(23720..23926)
                     /locus_tag="VQ878_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094590.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLER"
     gene            complement(23913..24074)
                     /locus_tag="VQ878_000171"
     CDS             complement(23913..24074)
                     /locus_tag="VQ878_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3094591.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(24433..25389)
                     /gene="lytA"
                     /locus_tag="VQ878_000172"
     CDS             complement(24433..25389)
                     /gene="lytA"
                     /locus_tag="VQ878_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET3094592.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(25765..27135)
                     /locus_tag="VQ878_000173"
     CDS             complement(25765..27135)
                     /locus_tag="VQ878_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3094593.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(27442..28608)
                     /gene="recA"
                     /locus_tag="VQ878_000174"
     CDS             complement(27442..28608)
                     /gene="recA"
                     /locus_tag="VQ878_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET3094594.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(28663..29919)
                     /locus_tag="VQ878_000175"
     CDS             complement(28663..29919)
                     /locus_tag="VQ878_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET3094595.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(30004..31020)
                     /locus_tag="VQ878_000176"
     CDS             complement(30004..31020)
                     /locus_tag="VQ878_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3094596.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(31028..31546)
                     /locus_tag="VQ878_000177"
     CDS             complement(31028..31546)
                     /locus_tag="VQ878_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3094597.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKITGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(31536..31979)
                     /gene="tsaE"
                     /locus_tag="VQ878_000178"
     CDS             complement(31536..31979)
                     /gene="tsaE"
                     /locus_tag="VQ878_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET3094598.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(32065..32685)
                     /locus_tag="VQ878_000179"
     CDS             complement(32065..32685)
                     /locus_tag="VQ878_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094599.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(33068..33931)
                     /locus_tag="VQ878_000180"
     CDS             complement(33068..33931)
                     /locus_tag="VQ878_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3094600.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            34435..36450
                     /locus_tag="VQ878_000181"
     CDS             34435..36450
                     /locus_tag="VQ878_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3094601.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLYVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            36452..37084
                     /locus_tag="VQ878_000182"
     CDS             36452..37084
                     /locus_tag="VQ878_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094602.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            37225..37503
                     /locus_tag="VQ878_000183"
     CDS             37225..37503
                     /locus_tag="VQ878_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET3094603.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(38012..38425)
                     /gene="ndk"
                     /locus_tag="VQ878_000184"
     CDS             complement(38012..38425)
                     /gene="ndk"
                     /locus_tag="VQ878_000184"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET3094604.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(38536..42213)
                     /gene="rpoC"
                     /locus_tag="VQ878_000185"
     CDS             complement(38536..42213)
                     /gene="rpoC"
                     /locus_tag="VQ878_000185"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET3094605.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(42246..45857)
                     /gene="rpoB"
                     /locus_tag="VQ878_000186"
     CDS             complement(42246..45857)
                     /gene="rpoB"
                     /locus_tag="VQ878_000186"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3094606.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            46273..46343
                     /locus_tag="VQ878_000187"
     tRNA            46273..46343
                     /locus_tag="VQ878_000187"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46305..46307,aa:Cys,seq:gca)
     gene            complement(46541..47872)
                     /locus_tag="VQ878_000188"
     CDS             complement(46541..47872)
                     /locus_tag="VQ878_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET3094607.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(48163..48987)
                     /gene="endA"
                     /locus_tag="VQ878_000189"
     CDS             complement(48163..48987)
                     /gene="endA"
                     /locus_tag="VQ878_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET3094608.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(49026..49214)
                     /locus_tag="VQ878_000190"
     CDS             complement(49026..49214)
                     /locus_tag="VQ878_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3094609.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(49207..50490)
                     /gene="murA"
                     /locus_tag="VQ878_000191"
     CDS             complement(49207..50490)
                     /gene="murA"
                     /locus_tag="VQ878_000191"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3094610.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(50514..50744)
                     /locus_tag="VQ878_000192"
     CDS             complement(50514..50744)
                     /locus_tag="VQ878_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET3094611.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(50802..51839)
                     /locus_tag="VQ878_000193"
     CDS             complement(50802..51839)
                     /locus_tag="VQ878_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET3094612.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(51823..52311)
                     /gene="coaD"
                     /locus_tag="VQ878_000194"
     CDS             complement(51823..52311)
                     /gene="coaD"
                     /locus_tag="VQ878_000194"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET3094613.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(52301..52840)
                     /gene="rsmD"
                     /locus_tag="VQ878_000195"
     CDS             complement(52301..52840)
                     /gene="rsmD"
                     /locus_tag="VQ878_000195"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET3094614.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(52905..53897)
                     /locus_tag="VQ878_000196"
     CDS             complement(52905..53897)
                     /locus_tag="VQ878_000196"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET3094615.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(54008..54691)
                     /locus_tag="VQ878_000197"
     CDS             complement(54008..54691)
                     /locus_tag="VQ878_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET3094616.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(54747..55487)
                     /locus_tag="VQ878_000198"
     CDS             complement(54747..55487)
                     /locus_tag="VQ878_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET3094617.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            55521..55799
                     /locus_tag="VQ878_000199"
     CDS             55521..55799
                     /locus_tag="VQ878_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET3094618.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            55877..56803
                     /gene="yidC"
                     /locus_tag="VQ878_000200"
     CDS             55877..56803
                     /gene="yidC"
                     /locus_tag="VQ878_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3094619.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(56878..57672)
                     /gene="pflA"
                     /locus_tag="VQ878_000201"
     CDS             complement(56878..57672)
                     /gene="pflA"
                     /locus_tag="VQ878_000201"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET3094620.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(57798..59048)
                     /locus_tag="VQ878_000202"
     CDS             complement(57798..59048)
                     /locus_tag="VQ878_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET3094621.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(59115..59942)
                     /gene="purR"
                     /locus_tag="VQ878_000203"
     CDS             complement(59115..59942)
                     /gene="purR"
                     /locus_tag="VQ878_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET3094622.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(60209..61150)
                     /locus_tag="VQ878_000204"
     CDS             complement(60209..61150)
                     /locus_tag="VQ878_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET3094623.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(61140..62396)
                     /locus_tag="VQ878_000205"
     CDS             complement(61140..62396)
                     /locus_tag="VQ878_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET3094624.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(62398..63060)
                     /locus_tag="VQ878_000206"
     CDS             complement(62398..63060)
                     /locus_tag="VQ878_000206"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET3094625.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(63023..63679)
                     /locus_tag="VQ878_000207"
     CDS             complement(63023..63679)
                     /locus_tag="VQ878_000207"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3094626.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQSKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(63690..64568)
                     /gene="rsgA"
                     /locus_tag="VQ878_000208"
     CDS             complement(63690..64568)
                     /gene="rsgA"
                     /locus_tag="VQ878_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET3094627.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(65161..65934)
                     /locus_tag="VQ878_000209"
     CDS             complement(65161..65934)
                     /locus_tag="VQ878_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET3094628.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(66624..67496)
                     /gene="rsmA"
                     /locus_tag="VQ878_000210"
     CDS             complement(66624..67496)
                     /gene="rsmA"
                     /locus_tag="VQ878_000210"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET3094629.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
BASE COUNT        19932 a        14990 c        12401 g        20329 t
ORIGIN      
        1 ccttttttaa acttttttta ttaattttac aacagcttca gttcgagctg tatgtgggaa
       61 catatcgacc gactggatat aatgaagatc atagacttct actaagcgta ccaaatcacg
      121 agccaaggtc gaaacattac aagaaatata aaccattttt tctggtacat aagtaagaat
      181 agtatctaat aacttatcat ccagacctgt acgtggtggg tcaacaatca aagcatctgc
      241 tcggtagcct tccttgtacc aacgaggaat aatctcttct gccgttccag cttcataatg
      301 agtattgtca aatcccattc ttttagcatt tcgcttggca tcttcaatag cttctggaat
      361 aatatccata cctctgagtg tttttacttt ctttgcaaag gcaaatccaa tcgttccaac
      421 tccacaataa gcgtcaatca aatggttttc tttatcaaca tccagcgctt ttactgcttc
      481 gctatagagg acttctgttt gctcaggatt tagttgataa aaagctcgag gggatagtga
      541 aaattcataa ttgagtacac cttcttgaat actctcttgc ccccagataa tctctgtctt
      601 ttcaccatat atctcactgg ttttagctgt atttgtatta acagctactg tcacaacttc
      661 tgggaaatct ttaaccaact cttttaccaa ttgagttaaa ttaagctggc ggtttgtaac
      721 aataataatc tgaacctgtc cggtctttct cgcgcgtcgg accataatag tacggacacc
      781 tagaactttt ctctcatccg tgattggaat ctggtgataa gtaagtaatt ctgctaagcg
      841 attagcaatc acttgggttt ccttatcttg taccaggcag tctttcaact ctactaaata
      901 gtgagagttt tgtgcatata agcccgcctt gacctgattt ttaaattttc gagtctgaaa
      961 ttgtaactta gctctgtaat attttggttc ctgcattcca atagttggac gaatttcata
     1021 attttcatat cctgcaggag caaatttttt cagcgcttga tgaagtaagt ccgtcttgaa
     1081 ctccagctgc ttatcataat gcaggtgcat gatttggcag cctccgcatt cattataaat
     1141 agtacaagat ggcacaattc gaaatttaga cttcttgttg accttcagta attttgcttc
     1201 aacaaagttg cgtctaatag aagtaatctg acaatagata tcttcgcctt tgagagctcc
     1261 tggtacaaag actaatgttt tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg
     1321 cttgattttt aatggtattt tttgtttcac tttcagattc atatgtctat tataccatgg
     1381 agtttctaag atatttaaga atatgttaca ataaaagcat gaattcaaaa acacctcgct
     1441 ttagtatact agatttccct gaacaattac gaagctatat caagggagct aatctctctg
     1501 atagttcttc tcattcaagt gcaactgtcc tatatataga ttcaggttac tatttaaaaa
     1561 tagatcaaaa aggcagatta gctcaagaaa ctaagattgc aagttggttc gaaactgaag
     1621 gattgggaac tccagtgatt acctatttat cagcaaataa ggacttcctt ctgactaaag
     1681 aagccattgg cagcaacgct ctcgcttttt taaatcaacc cgaaagactc tgtcaaaccc
     1741 tggctcaagc attaaacaaa cttcacagtc ttaaaccaca atcttttccg tcggaaaatc
     1801 atctgaagcg ttataaagaa aaagccttaa aaaactatca gaaggggact ttttataaca
     1861 agactcttct gcctcaattt cacattcaca gtcgtgaaga agcttaccaa ctgatacaag
     1921 agaaaggtta cattctcaaa gctgatgctt ttattcatgg agatgcctgc ctgccaaatt
     1981 tcatcttgaa ggatgcctct catttttctt gctttattga cttgggattg gctggtttta
     2041 gtgaccgaca tatcgacctc ttttgggcaa tttggtccct tcattacaac ctacaagatg
     2101 ctacgtatgc tgaattattt ctcgactatt acggtagaga atatgtaaat atggataaac
     2161 tacgacttgt tgcagctttc gaagcattta gatgaaagga aattatgaaa atcacaaaac
     2221 ttgaaaagaa aaaacgtctc tacttgatgg aactagatgg acagcaaacc tcttatatca
     2281 cggaagatac cattgtccgt tttatgctgt ctcgagataa ggtcattagt aaagaggaac
     2341 tgaccgagat tcaggatttt gcccagtttt cttatggtaa gaatctcgct ctctaccact
     2401 tatcctttaa agcacgcact gaaaaagaag tcagagaata tctgaaaaaa tacgatattg
     2461 ataaaaacat cgtttctcaa gttattgcta atcttaaaga agataagtgg attaatgatg
     2521 gtcagtacgc ttatgctatc atcaatacca atcaactttc aggagacaag ggtccttatg
     2581 tgctgactca gaaactagct caaaaaggga tttcaaaatc tactatagaa gagaacttga
     2641 aagaatttga tttttctgaa gttgctcaac gtgtagctaa taaactattg aaaaaatatg
     2701 agggaaaact tccatctcgt gccctgcaag ataagattat ccagaacttg actaacaagg
     2761 gcttctctta ttctgatgct aaaattgcct ttgacgactt agatagccaa gttgaccaag
     2821 aaacgactca agaactcatc ttcaaggaac ttgataaaca atatagtaag tatgctcgaa
     2881 agtatgaagg atacgaactg aagcagcgtt taactcaagt tttagcacga aagggctacg
     2941 atttttcgga tatagcaagc gctcttagag aatatcttta atatttccaa gtgaaattca
     3001 cagattttag gtaattttat ggtacaatag taaatgataa acttataaat tgtagaaagt
     3061 tggttagtta tgaagcttcc aaaagaaggc gactttatta caattcaaag ttataagcat
     3121 gatgggagtc tccaccgaac ttggcgggac accatggtac taaaaacaac agaaaacgcc
     3181 attattggtg tcaacgatca tacacttgtt accgaaagtg atggtcgtcg ttgggtcact
     3241 cgagaaccgg ctattgttta ctttcacaag aaatattggt ttaatatcat tgccatgatt
     3301 cgtgataatg gaacttctta ctattgcaat atggctagcc cctactatct ggatgaagaa
     3361 gcactgaagt atattgatta cgatttggat gttaaaattt ttacagatgg ggaaaaacgt
     3421 ctcttggacg ttgaagagta cgagcgtcac aaacgcaaaa tgaattattc tgatgacttg
     3481 gactatattt taaaagaaca tgtcaaaatt cttgttgatt ggattaacaa tggacgtggt
     3541 cctttctcag aagcctatgt aaacatttgg tacaagcgct atgtagaact aaagaatcgg
     3601 taaagttgtc aaaggtcagg aacaaaatcc tgaccttgtt tttttggtag tataaaataa
     3661 attgtgtaaa cacaaaaagg aataaatcca ttatagcaga gttacaacac attactagaa
     3721 agagatttat tcctacgact cagtttggca tgcttaactt cctaactcaa aaacaaagca
     3781 tcgattaatt tatccgttct tcttttgaaa cagatttgaa ctgataattg ctcgttttaa
     3841 tttaagaagc tcttttgagc aaaacttcat ttttttaaga gtccaacaat ttctgtctat
     3901 cgcttttcta ctagcaaaaa aacctacctt gaggcaagtt ttcatttata tatctaattt
     3961 cgtaatagta tagtaaaatg aaataaggac agtcaaatcg atttctaaca atgttttaga
     4021 agtaaaggtg tactattcta gtttcaatct actataaatt tgatatgaga atagtctttc
     4081 tcaacatcct tacccaacaa gaatgctgta gcgtccttct taacttgaac caggtcaata
     4141 ttctgggctt gggctgcata gacgcagcca caataacatt gacgatagat atcatactcc
     4201 tcacacatct ctactgaacg tttgtagcct tgatttttct tgaaatcgtt gggaagatag
     4261 tgggtcgtgt aaattttttg cacatcgatt ccgatgctgt tgatggtttg agaattctta
     4321 tgaggactga tggtcaaggc tgaaccaaag tagtcaaagc ccaagtccat agccacttgc
     4381 gctgttttat ccagtcggta gtcaaaacaa accttgcaac ggtcgccacc ttcgggctcc
     4441 tcctctagtc ccctaactag ttttcggtat taattgggtt cgtagggagc ttctaggtac
     4501 tgaaccgtat ttcctgtccg ctcattaaaa tcactaacaa atttcttggt gacatagacc
     4561 cgcttatggt attctacctt gggatggata ttagaattgg caaaatagat ggtcacatct
     4621 gcatacttgg tcaaatattc tagtgtatag gtactacaag gggcacagca aacatgcacg
     4681 agaatggttg gccgttgctc atttttctac catacttcta ccattttctg catgacacgg
     4741 tcataattaa tcttctgatt ggggggcatc ttgcacagaa ttttttctac atcgatcatg
     4801 ttcttctcct ttttctagtc ttattttatc atataagtta ggagagctca aatcaattta
     4861 gaagtgaata ttataaaaag aagggttagt cattccctcc ttttgtgttt tttataagtt
     4921 gttttctata gaatgcttac atcatcccgc ccatcatgct tggatccatt gctggagctg
     4981 gggctactgg ttctggttta ttggctacga ctgcttctgt tgtcaaaatc aagctggcta
     5041 cagatgctgc attttgtagg gctgaacgac tcactttaac tggatcaatg ataccttgat
     5101 caatcatgtt aacccactcg ccagttgctg cgttgaatcc tataccaagc tcagcatttt
     5161 tcaaacgatc gataacgata gatccttcaa atcctgcatt gtgagcaatt tgacgaacag
     5221 gttcttccaa agcacggaga acaatattac gtcctgttac ttcatctcct gtcaattcca
     5281 aggtagcaac agctggaatc acattggcaa gagctgttcc accacctgca acaatacctt
     5341 cttcaacagc tgcacgagta gcgttgaggg catcttcaat gcggagtttc atttctttca
     5401 actcagtttc agttgcggct ccgaccttaa taaccgctac accacctgac aatttggcca
     5461 agcgttcttg caatttttca cggtcaaatt cagaagttgt agtttcgatt tgagacttga
     5521 taaccgcaac acggtgagaa atcgcttcag gatttcctgc accttctaca ataaccgtgc
     5581 tatctttgtc cacggtcact ctcgctgctt gaccaagagc ttcaattgtc gcatctttca
     5641 actcaagacc aaggtcttct gtgataactg ttccgcctgt taagatggcg atatcttcaa
     5701 gcatggcttt gcgacggtca ccaaaaccag gtgccttgac tgctactacg ttgaaggttc
     5761 cacgaatctt gttcaaaaca agagttggaa gagcctcacc atccacatca tccgcaataa
     5821 tcaagagtgg acgattgctt tggagaatgc tttccaaaag tggcaagatt tcttggatat
     5881 tggaaatttt cttgtctgta atcaaaatgt acggattttc aaggtcagcc accatttttt
     5941 cgctatctgt caccatgtac tgtgaaaggt aaccacggtc aaactgcatt ccttctacga
     6001 cttcaagctc tgtttccata ccacgtgact cttcgatggt gatgacaccg tctttgccaa
     6061 ctttttccat tgcttcagag atgtactcac caactttttc agaacgagaa gatacggctg
     6121 caacttgagc gatagcttct ttattggcaa cagggatggc gttgtttttc aaagcttcaa
     6181 ctgctgcggc aactgctgtt tcaatcccac gacgaatacc gattggattt gcacctgctg
     6241 tgacgttttt gattccttca cggacgatag cttgggtcaa gactgttgca gtcgtagttc
     6301 cgtcacctgc gatatcattg gttttagaag ctacttctga tactaactta gcacccatat
     6361 tttcaaaatg gtcttccaat tcgatttctt tggcaatagt cacaccgtca ttggtaatca
     6421 atggtgagcc aaatgatttt tcaagaacga cattgcgacc ttttggtccc aaggttactt
     6481 taacagtgtc tgcaaggata tcgacaccac ggaccatagc tgaacgggca tctgatgaaa
     6541 atttaatttc ttttgacata cttactttct ccttctattc ttcaatgatt gccaagatgt
     6601 tagcttcgcc tacgatgatg tacttttcat cgccatcttt gacatcaaga cctgcgtggg
     6661 cttcaactaa gacacggtct ccagttttaa cacttggagc aaccaagtca ccgttcaagg
     6721 tacgaacacc ttgtccagta gccacaactt gggctgtttt ggttttttct tgggctgaac
     6781 ctgcgagaac aaagccccca acggtttgtt ctttttcttc tatttttaag accacacggt
     6841 cccctaatgg tttcaacatc tgatttcctc cataatgaga tagatattat tagcactctt
     6901 tatacctgag tgctaattca tagttctatt gtatcactta gtcagaaata atcaagaaaa
     6961 aagtctgact ttctcaagat aaaaagcctg agaccaactc agacttttta atgtttatac
     7021 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgctcaaa gcattgcttt
     7081 gatgttgtgg ataaagctaa cgtggtttga agagattttc gaagagtatt aaaatggcaa
     7141 ttcttcctct tccaagacta aatctgccaa atcttggcct gcattatttt cacgcatggc
     7201 acgttgagca cgactttcca agagttggaa tcctgttaca agtacttcgg tcacgtagtt
     7261 catttggcca tttttctcaa agcgacgggt acgcaattct ccatcaacgg aaatgagact
     7321 acctttggtt gcgtagcttg ccaaagtttc tgctagtctg ccccatagga ccatattgac
     7381 aaaatcagct tcacgttcac cgttttggtc tttgtaacga cggttcacag cgatagttgc
     7441 tcgcgctacc gacttgtcat tgttggtttt gtgcaattct ggtgtagacg ttaaacgccc
     7501 aatcatgata actttattat acatattttc ttcctcctac ttatctattc gtaggaaatc
     7561 aaaaaaagtt acagaaattt gtaacttttc gaggaaattt cttatttttt atgaatcatg
     7621 aaacctgtcg cctgttgatt ggccataatg gtcatatctg taatctgaac acggcgaggc
     7681 tgactggtca catagactac tgtgtctgca atatcctgag cttgcaaggc ttctattcct
     7741 tggtaaacgg acgcagctcg ctctttatca ccatgaaaac gaacagttga gaaatctgtt
     7801 tcgacaatcc caggctgaat ggttgtcacc ttgatatccg ttgcgatggt atcaattcgc
     7861 agtccatccg aaaaggtctt aaccgcagcc ttggtagctg agtaaacagc ggcaccagca
     7921 taggcgtaga ttcctgcggt tgaccccata ttgataatat gaccttgatt gacttttatc
     7981 attgctggca agaaacagcg agtaaccgcc atcagacctt taacattggt atccaacatg
     8041 gtcaacatat ccaactcctc atagtcttga tagggagcca agtcaagagc cagtccggcg
     8101 ttgttgacca agatatcaat cctccctatc gtttctagaa tatcagagca aacagtcttc
     8161 accatgacca tatccgtcac atctagtgga aaagtccaga cggtttgatt tggaaagctt
     8221 actgcaaact ccgacttgag gatttctaat ctgtctatcc gtcgtcctgt tagaacgaca
     8281 tcctcaccct gctccagata agcacgcgca atcgcttcac cgattcctga ggttgctccc
     8341 gtaatcacta cattttttac catcttattt ccttctatca gatgctgaca agttcctagg
     8401 cagtccagtg tttcgctggg tcgaacggtg ttccgacaac ttggtcttct gataattcaa
     8461 gcaccccacg tttttgcgga gcatttggca aatgcaattc acgaggacta cacatcatcc
     8521 caaaactctt ttcaccacga agttcgcctg ggaaaatgaa attccctttt ggcatcatgg
     8581 caccaggaag agccacaatg gttttcaacc caacacgcgc attaggtgct cctgcaacga
     8641 tttgcactat cttgtcactt gcgactgcaa cttggcagat gttgaggtgg tcactgtctg
     8701 gatgagctac catctcgaca atttcaccaa caacaaactt aggttcctta tcattaacaa
     8761 tttcttctgt aaaaccttcc gcctgtaatt cttggttcaa acgagcgact tgctcatctg
     8821 ataaaaagac ttgaccgcgc tctgcaattt caaacaagct cgaaacctca aaaatgttcc
     8881 aagctactgt ttccccattt tctttgagga aaacacgggc taccttgcct ttgcgttcca
     8941 cattcagttt ggcatctccg ctatttttca cgatgaccat aaggacatca ctgacatgtt
     9001 ctttgttata cgtaaaaatc attgtttcct ttttctccta tttcaatcct gctaaaaaat
     9061 cgttaatttg ctccttactt ttacggtcgc gattgacaaa acgaccgatt tccttgtcct
     9121 tttctagaac aacaaggcta ggaattccgt aaacatccca gagtttggcc aaatccatat
     9181 actgatctcg gtccattcga ataaaggtga actctggatt ggtctcttca atctctggta
     9241 aggcaggata aatataacga caatcgccac accagtctgc cacaaaaagg aagaccttct
     9301 tgcccgcttt ttccactaaa gatgctaatt cttctaaact tgctggctgt atcataagac
     9361 ttcctcctca tagactaggt cttcattttc atagacaaag gtataatgac ggccatcctc
     9421 aaaaatgacg ccaccaacca agctctccag actgctttcg taaacttgaa cataaagggt
     9481 cgcaatttcc cccatgtcgg aaaaatggtc tcgcacaatc tctgtcaact cttcctgagt
     9541 cttcatgagc ttacggtcat ctgcaacttt tttcgtagca agagcaaggc ttccgatacc
     9601 tagcagagcc aagcctgcca tccacatttt tttagctttc ataccattca ttttaacaca
     9661 aaaaaggctt caggacaaat gaggaagcag cagaaaagca agtaaaaagc ctcttccttt
     9721 aaggaaaagg acttcttata ctaagagcaa actagaaagc tagccgcagg ctgctcaaaa
     9781 cacggttttg aggttgtaga taaggcgacg ttgacgtggt ttgaagagat tttcaaagag
     9841 tattattctt attgccaggc acctaagttg ccaacgtagt aaccatcagg tgtgtaggta
     9901 ttgcgaagca tcttacctga tgaagccaga taatactact tgccattgtc tttgacccaa
     9961 tcattcgcaa tcatggaacc agaagaactt acataatacc attctccctt gtcataaacc
    10021 caagtactga ctttcatggt tcctgagcaa ttaaaggcaa aaaaactgtc caatatcatt
    10081 cgttttttaa aagcattcga cactacatca tctacgctgt agtacataga tacatcaaac
    10141 gtaaaagcca aaatatcgaa aaatatacaa cttttaaagg cagcatttca ttttttaaag
    10201 tctaacaacc atagaactga aatcagagca aggcatcaat ttcctactct tagtacgcct
    10261 attttgatgg ttgaagtgaa gattttttta tttagcgtag acaatttcca acttcccaaa
    10321 agccacatct ccacggataa tcaaggtttt gctggttggg gctacaggag cgtccgcctt
    10381 ggctgcacca aaggatgttt ctactttcaa atcgacacgc cagtgttgcg gaacatagac
    10441 agttgcatta ccaaaagcta cttcaatatt taaagttgca aaatcaccta acatctctgc
    10501 attgtcatag tagatttttg cattgccaaa accaacttct acttggtctt ctaccaattc
    10561 ttggtcttgc ttgtagaaag tccctgtccc aaaagcaact tccttatcta taagaatgtt
    10621 tttttcacca tcataccacc attttttccc attccaagtt ctgttagaat gagtcaacat
    10681 atttactccg agaacgatta gaactcctgc ccagattagt gtctggtttg gaatcggtaa
    10741 aatgccataa aagtggttag caatcattaa ggctactaga gctgtaaaag aggctgaagt
    10801 taagtggcga cgcaacaaag ctccaactga ttggtaggca aaaaaagcaa taccaatcaa
    10861 gggccaaatg tgccctccta gagaagggat tccaaaattt ccttgtacta atattaaagc
    10921 tgctagtaca agcaacacaa taccaaatgc tttctttttc atgttcttac ctcatatttc
    10981 ttagattttc ttttaggagg gattggtaat gccgtgacac atgaacctcc ttgtgggttt
    11041 gataaaagga aatggtgccc gttcctgaaa aggacttgtc caccgaatag atttgccgaa
    11101 tattaacgat cgttgacttg gatactcgac taaaatagcg aggaaggata gcctctaact
    11161 catagagttt gagccgaact tcgtaggcat ttttctgggt atgggcataa atcttgctac
    11221 cttctgtctc aaagaagaga atttccgaca agtccagata atattcaccc gtccccttgt
    11281 aaaaaatcaa cctaggagac ttggattctt gcaagagccg ttgcaagtct gcaatttcat
    11341 ctgtcaaagt gggggtcttg atgacaattt cagtctcctc taaattgccg tcaatctcaa
    11401 ttcgtaactt catcacatct cctttctgac tctactatat caaagctaag ttaggaatac
    11461 aagggcaaaa aagcaagtgg tcaatttgaa gcagtaagtg gttgtaggac tagcttaact
    11521 tacatgtcag aataagaaga aaaggaatcc ccacaccaga ccacaagcat agccaaccaa
    11581 gacatccttg ggataatgaa caccccctaa aaccctcacc aaccccagca aagctgaaaa
    11641 gatcaagcat actaagccaa taggtagact agcatgcaga caggccatgg agatgatagt
    11701 tgcagaaaag acatggcgac tgggcatcga ccgtcccgaa ctatccttat caagaagggg
    11761 acagatatcc caagtttcat aaggtctcgg gtgattgatt tttttacgaa acagggacaa
    11821 ggccacaaaa cctgatgcag gaataagcac ataaactcca acttgctgac caagtcctag
    11881 ttgcaggtaa gtggtgacta gcaagatcag atagaccagg ggcatggcga ctgtcatcaa
    11941 acgattgaaa ctgcgtaata ggaataaaag aattggacga ctagttagtc tggatctgat
    12001 atttcgatac cattcttgat aatttttcat ttatgcttct catacttttc tagaacttgt
    12061 tgagatgttt tccccttggc aagccaatcc actagcttgt ccaagcgacg tatttcctgc
    12121 atcagaggat catcaatttc ctcaatacgg acaccgcaaa tcttccctgt aattgcaatt
    12181 cgttcaggga cataatatgg tgcttgtcga aaaaaatctc cgtaagtaac atccctatcc
    12241 agacaagtaa gaacgtcact cacttcatac cctgtcaacc aactggtcac ttggtgaact
    12301 gactctgcct ttccaccctt tcgctcaact tttgcaatca aggctaagta gacagcagca
    12361 aatttcatat tgtataattt ctgactcata cttctctctt tctatgtgta ctagtataaa
    12421 taagaaaaag aaggccgtca agccttcttt tgatttattc ttctgcttca tcttctgtaa
    12481 attgactatt gtacaagtca gcgtagaagc caccttacac catcagttcc tcatagttgc
    12541 cttgctcgat gatatttcca tctttcatga ccaagatcaa gtctgcattt cggatggttg
    12601 acaagcggtg ggcaatgaca aaggatgtgc gtccttccat caaacggtcc atggcttttt
    12661 ggatcaattc ctctgtccgt gtgtcaacag aagaagtcgc ctcatccaaa atcaaaagcg
    12721 gtgcatcctt aagaagggca cgagcaatag tcaatagttg tttttgtcct acagacaagg
    12781 tcacggtgtc atccaagatg gtatcatagc catctggcaa ggtcataata aagtggtgaa
    12841 ttcccacagc cttactagct tccatcattc gttcatcact aatccctatt tgattataga
    12901 tgagattgtc tcgaatagtt ccttcaaaga gccaggtatc ctgcaagacc attgaaaagg
    12961 catcatgcac ttctgaacgc gtcatagcct tggtatccac accatcaatg cgaatacttc
    13021 ccttatcaat ctcatagaat ttcatcaaaa gattgacaat ggttgtctta ccagccccag
    13081 tcggcccaac aatggcaacc ctttgaccag catgagctgt cgcagagaag tcatagtctt
    13141 gaacattgac accgtccacc agaatttctc ctgctgacac gtcgtagaaa cgtggaatca
    13201 gattgaccag agttgattta ccagaaccta ttgacccaat aaaggccact gtttgaccag
    13261 tttctgcttt aaagctaaca tgttcaataa ctgcctccga atttgccgca tagcggaagg
    13321 tcacatcctt aaactcgacc tgacctttga agttttcatc agtcagctgc acttgagcag
    13381 ggttttggat agaagaatgc aaatctaaaa cttgattaat ccgcttagca gagaccatag
    13441 ttcggggaag aacgatgaag agtgctccca tgagaaggaa gtccatgaca acctacatgg
    13501 cataagacat gaaaacaatc atgtcactaa agaaaggcag acgcgctatc ggagcagcgt
    13561 cgttaatcac ataggcccca atccagtaaa tcgccacact caaaccactt gaaatcccca
    13621 tcatgatagg attcaaaata gccataagac ggttgacaaa caaattttaa cgggtcaatt
    13681 catcatttac tgctgcaaat ttttcatttt gataatcctc tgcattgtag gcacgaacga
    13741 cacgaatacc tgttaaactc tcacgagtga tactgttcag tttatctgtc agcccctgaa
    13801 tcaaggactg ttttggaaag gctagcgtca tcaaaacggt cgtcatcagg acgttgacaa
    13861 tcactgccac aagtacggcc cagagccagt attctgaatg acctaaaatc ttcccaatag
    13921 cccagatagc cataattgga ccacacgtta ccacttgcaa gtccatagta atcaacattt
    13981 gaacttgagt aatgtcattg gtagtacgca tcaagaggct aggaattgaa aatttcttaa
    14041 tctctgtctg cgagtaatcc aaaactcggt taaaaatatc acttctcagc ctactagtat
    14101 aagaagccgc cactcgggat gcaaaaaatc caactgcaac tacggacaag aaggcaagaa
    14161 agggcattcc catcatcatg cttgccggct gccacaactc atctaaatta gttccttgac
    14221 tacctagcaa atccgtaatt ttcgagatat aggtcggcac ttccaactct agatagaccg
    14281 aaaagcaagt aaagagaatg gctagtaaaa tcatccccca ttcttttcta ctaattcttt
    14341 tggctaattt ctttattctc tcctcctatt cccttgatat ttgcctgtag ttgaccgaga
    14401 actttctcaa aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg
    14461 cgttcaaaaa agccttaacc tgttgcatct gagaacgtgc tttgtccgtc agacgaacaa
    14521 acttagcccg cttatcaaca ggactcgcct ccaattccac caaaccattt tgcactatac
    14581 gcttaaccag attactagca acagacttgg taatattgag ttcctgctcg atatctttaa
    14641 tcaagaccaa gtcttggttt ttctcgcgat tatccaaaaa acgcacaacc tgaccttgcg
    14701 gcccacccat aaattcaatg ccgcaacgtt tggcttcctt ttgcaccatc aggtaaattt
    14761 gatgaccaaa acgcttaaag actaacatcg gtttatccat aatctccccc ttctaaataa
    14821 aaatagttct ctggagaata attaaatttc tatgagaact attttcttga ttaaaaaaat
    14881 cccaagtgat tttctcactt aggatcatgt tctataggtt aaattaaaac ccatctacgt
    14941 tcgtataaat cttttggacg tcttcgtcgt cttcaagaac gctgtaaagt ttttcaaagg
    15001 tttcaaggtc ttcgcctgac aattccactt ctgactgagg aatcatttcc aattcagtca
    15061 cttggaattc ttcaatacca gactcacgga gagcaacgat agccttgtga aggtcagttg
    15121 gcgctgtgta aactgtgatt gtaccttctt gtgcttctac gtcatccaca tccacatccg
    15181 cttcgagcaa ttgctcaaag actgcgtccg catcttcacc tccaaataca ataacacctt
    15241 tgttgtcaaa aaggtaagaa acagaacctg aagcgcccat gtttccgccg tttttaccaa
    15301 aggctgcacg gacattggct gctgtacggt taacgttaga agtcaaagta tccacaatta
    15361 gcatagagcc atttggccca aaaccttcgt aacgtccttc tgtaaaggtt tcgtctgtgt
    15421 ttcctttggc tttatcaatc gctttatcga taatgtgttt tggcacttgg gcttgtttag
    15481 cacggtcgat aacgaatttc aaagctgagt ttgattctgg atctggatca ccttttttag
    15541 ctgctacata gatttctaca ccaaattttg catatacttt agagttagct ccatctttag
    15601 ccgttttctt ggctacgata ttggcccatt tacgtcccat taggaatctc cttttttcac
    15661 attttaatct ttcttattat aacacaagtt tttttgattt tcactagagg aaatggattt
    15721 tattagcaaa tcaagctagg atagcacttt acctgctaag atggtcttac ctttctatct
    15781 ttatcaacag acactcatcc acattcaaaa aacaaactag accattatct gcaaatagaa
    15841 agtttcagcc aagtttgaca aagtcagctc aaattactgt ttgaagtttg tagatataag
    15901 cgacaaaaac aatcatactg caccttttgt tgacagtcta ctccagacat atcatagttc
    15961 aagtaaatac tttgaaatcc aacagttctt ataggcgcta ttgtattcta agaaatcaat
    16021 agaagagttt ctaagcaaac ctctaatact caataaaaat caaaaagcaa actagaaagc
    16081 tagccgcagg ttgctcaaaa cactgttttg aggttgcgga tagggctgac ctggtttgaa
    16141 gagattttcg aagagtataa tttacgtgtt cccaagatgg agaaattaga ctagtacact
    16201 ggcacttcta aaccattgct agcaattgat ttgttcatat ttaatttcat tttttccata
    16261 aatgggtatt agatataaac agcaaaatat ttccgatacg tgtcattctt gaatttccaa
    16321 tcatctaaaa caagtaaagg ataatcaatc ccctgtatat caaggaattg gctacccttt
    16381 ttactttttt acacattctg tttgatagat tcattttaac atcacgagca tactccaatg
    16441 gaaatcgcta ggcaagagat aaactttcag atatccgcag agagatcatc gcctcttttt
    16501 gtcgcaagca ttctcctcta ctagtcattt tctaccttat cttctacctg aggatagaga
    16561 gttgttcccc aaatagaaat cgtccgctta cgcactagtg gcaaatcggt tttttcataa
    16621 accgtacgcc accattccca ggcaagcccg gtacactctc taattttgac agagagatta
    16681 cgaacattcc cttttaaagg aatactagtg gtaaagtgag ccgtcaaatc ctgcccattt
    16741 ctgtcccaag ccttaggagt caagacttcc ttaccttgat gatcatagga taattcatcc
    16801 caagtaatat aatattgggc aacataggca ccactatgat ccagcagtaa atctccgttt
    16861 ctgtaagctg taaccttagt ctcaacatag tctgtactat tttgaaaggt cgcaactaca
    16921 ttgtcacgta aaaaagaagt tgtataggaa atcggcaagc ctggatgatc tgctgtaaag
    16981 cgactgcctt cttgaatcaa gtcctctacc atatccacct tgcctgttac aactcgggca
    17041 cccgaacttg ggtcgccccc taaaataacc gccttcactt ctgtattgtc caaaatctgc
    17101 ttccactctg tctgaggagc taccttgact ccttttatca aagcttcaaa agcagcctct
    17161 acttcatcac tcttactcgt ggtttccaac ttgagataga cttggcgccc ataagcaaca
    17221 ctcgaaatat agaccaaagg acgctctgca gaaattcctc tctgttttaa atcctctacc
    17281 gttacagtat cttgaaacac atctcctgga tttttaacag catctacgct gactgtataa
    17341 taaatctgct taaaattaac aatctgaatc tgcttttcgc ctgaatggac agagttaaaa
    17401 tcaatatcaa gagaattccc tgtcttttca aagtcagaac caaacttgac cttgagttgt
    17461 tccatgctgt gagccgtgat tttttcatac tgcattctag ctgggacatt attgacctga
    17521 ccataatctt gatgccactt agccaacaaa tcgtttaccg ctccgcgaac acttgaattg
    17581 ctggggtctt ccacttggag aaagctatcg ctacttgcca aaccaggcaa atcaatacta
    17641 taagtcatcg gagcacgatc gaccgcaaga agagtgggat tattctctaa caaggtctca
    17701 tccactacga gaagtgctcc aggatagagg cgactgtcgt tggtagctgt tacagaaata
    17761 tcacttgtat ttgtcgacaa gctccgcttc tttctttcga taacaacaaa ctcatcgggt
    17821 agctgattac cctctttgat gaaacgattt tcaatacttt ctccctgatg ggtcaagagt
    17881 ttctttttat cgtaattcat agctagtata aagtcattta ctgctttatt tgccatcttc
    17941 tacctcctaa taagttcctg gattgagttg cataaactca gacttgttca gcgaaatcag
    18001 ccgtggttgg actaagtgat ccaaaatttc ctcgtacaat tcttctgaga cattgcgtcg
    18061 ccgtctggct agataagaag tcggaataac cgtattatcc aacataaata ccttatctaa
    18121 gtcaatcaag gttggtcttg taaaaggatt acgagctaga tccggctctt ctatcataaa
    18181 gttcttgacc aaacgtctgg tcaagagagc tggtttgaag gtctgatttt taaccaactc
    18241 tttgttttta gtcatgctgt tgtcaataca gatatacata tgattcttca cagccaaatc
    18301 gctactaata gtcggaaaag gcaaataaag agctacaaca tctcctctct taatcaagca
    18361 agagcacccc cttttctcct aatgtaacat agacaggatt gaccaagtct tctgattgac
    18421 tcagaatttc caaagtttga gtttggcgcg ctgtcaattt agtagcatct tgtctcttca
    18481 atacaaaatg cttgtcgcca ataaccttga caatataatc cttctccaaa gctgactggt
    18541 aaatccacat cagatgttgt ctgtcctgag aactcaagag agaaggattt tcaagcctcc
    18601 cgatagtctg ataaaaatca aaaacaggag ctaactcctg ccaatctgat tggctagttg
    18661 tcaaggctag aaaaagggct ttgcgagctg atacttcttg gttagccttg agagttactt
    18721 tcccctccaa gttttttaga aatcgggaaa ctccagaaag caaatttttc tctaactgcg
    18781 agaaataaaa acctttcgtt cccagacata agtctttcat gtcgctttct ctagcaaata
    18841 agagctcaaa catttgatag taaaagaaaa atatctggca ctgggtcgcg ctcatctttt
    18901 ccttatcggc ttcttttttt aaccagagca agggcgacag gtaactggat tgagacattt
    18961 cctctacctc ctactctttt ttaactggag catctgcact agctgccact tcttttgact
    19021 ggatactttc ccactggtta atctcctctg agataagacc ttcgcatgtc ttgacaaata
    19081 gggcaaaagc cttggtcttt cctgcatatt tctccgtttg gcattgatag aggaattttt
    19141 ctttctccag gagttgcgca gttttttggt aagaaatcca attttccttt gcattataca
    19201 aattgataat cccctcacac agcaagccga gactggataa ggcaaccgaa atcaaacggt
    19261 agcgatcacc tggcatagga atagcacaaa agacagctat gaggaaacct gccacgattt
    19321 ctgttatttt taatacctta tagcgcctac gatgttgaac gcttttcttt aaaaaatgag
    19381 ctatctgtac gtctaatcgc tctgtcaggt acatttcttc tggcgtcata ttcgtaactc
    19441 ctttcattta ctttgataac catagtataa catatttgaa tatcaaagta tagtaaaaac
    19501 tggactataa cttattagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaatt
    19561 atgaagcaag taaacaacta actgatgcac gatttaagcg tcttgttagt gttcagcgta
    19621 ccacttttaa agagatgtta gctgtattaa aaacagctta tcaaaaaagt cggacaagct
    19681 ggtaaaatct tggctgacag taattatcaa gggctcatga agatatatcc tcaagcacaa
    19741 actccacgta aatccagcaa actcaagcca ctaacagttg aagataaagt ctataaccat
    19801 gcgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa aacgtttaaa
    19861 atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgagt
    19921 gctggtatta tcaatcatga actaggattc tagttttgca ggaagtctat tatatatatg
    19981 cacagacata tgaaatcttt ttgatacagc cttcttttta catagagaga cagcagttat
    20041 gatatattta tccattcaca acatcttctg taccaatact acaataattg gtacattttg
    20101 attacacaat cgtttcaaaa aatatgatgg aagactgagt attttatagt aattcccttc
    20161 ctatcaacta gatcaaccag ttgagtgttg aatgttgaaa caccctagcc tcagcaaagg
    20221 actatgatca gcatttccta gccaatagga cgctccaaat cacctattct aagtccatca
    20281 ctagcttggt cagtaagata cagactgcaa ggcaagactg acgtggttga tgagattttg
    20341 gaagagtatt acaatcatag attcaccagt agacttgacc gcagatttaa ctatagtaga
    20401 ttgaaactag aatagtacac ttctgcttct aaaacattgt tagaaatcga tttgactgtc
    20461 ctgatcaatt tgtcctgttc tcgtttcatt ttactatact aaaaaaccac ctgaaacaaa
    20521 tcaagtgact agaggataaa aacaaagact gggcaaaaag ttttgaaaag caaaaaacgc
    20581 ataatatcag gtcttgaaaa accttgatac tatacgtttg attgtgggaa gattgacttc
    20641 attttctcct gaaattgaag ttttttctag tttccaggta tagacgaatt caatatagcc
    20701 atctcgctac aattatttta accatcgaaa aaatttttca gaatttcaaa aatttcattt
    20761 tgatctaatg aaatgtcatc attttgaaga atagttgact tcacaagctc taattctatc
    20821 acaaagcggt gcatgtctgc ttttaccgca ctacttgatg ttatagccga taacttttca
    20881 tctcctagca aggaagctgt caaacgggta aggtcattca aatgcttttt aatggactta
    20941 cttaaacctt gagcacctgt agcagagcgt tccctcatat ccagccaagc tttagcctta
    21001 aaaataatta atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
    21061 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
    21121 gtatagacca caattactca ataccgaata cccctgaatg gtttcttttt catgcaccaa
    21181 tatattataa taatcttcat ccaataataa ggctgataaa ctagcatctt ggtcaaaatg
    21241 taagggaatt tctcgaccgt ccttctttaa tggatattct ggtaagatac taaatagttc
    21301 aatcatagaa ggaaactcag aattagttgt tgtaaatcga aaaagctgcg ctttctcatc
    21361 tttctgactt ccttgatact ctcccaattc taaaaaatga ttcaaggtag tataaaattc
    21421 cttatttttt acttcatcaa tgatgaccat atcataatct tttgttgtgc gacttttaaa
    21481 tccttgcgaa tccaatacga tagaggtagc agttccccca atcagaacat aatagttctg
    21541 aaaatccgca aacatttctt gaaaaataac tttcgtatta gctggcatca tcttctccca
    21601 gatactgtaa tatcatattt tctagtgctt cactctcttc ctctatacgt gggtcatcat
    21661 catcttttaa ggtcaaataa agagaaatcg gatctacaaa ttgtttatca tgattatttt
    21721 taaaatcatt ccaaaactca gatacaaaag gacgatattt ccatatctct agcatctttc
    21781 attttaaaac atgctgagaa agtggcaagg ataactgatt gaattttctc tgccatatga
    21841 catagctagt attttcatcc gtttcagcta aaaaagttga atgcgacaaa gcataagcac
    21901 caccatatag aaggttagaa acagatttta tctgctttat atcgccatct ggcaataaaa
    21961 aggcaatcca cgttaattgt tcgctaggta ttaattcctt agggacttca gtatcattcg
    22021 cattcagtac tagtcccaat gtagggaaga agaggtttcc cttaaagtct acaaacggaa
    22081 ctctagcttg aagtaattgc tttttttcac cgtctgataa cttcgaaaac accaaaacaa
    22141 catccatatt ggctttatca cccatagtgc gagcctgagt aacaaatgaa ctcaaactcc
    22201 cccttctctt ttctttaatc aataaaaatg attccttatg aaaagtcatt tgagtatact
    22261 caaacttttt tacaaaactg attggtaaag tcaaagtcag ttcctcaata ctgacatcaa
    22321 cataaaagga ttgaaaaatt gacattatct ttttgacatt catgtttttt ccttattcta
    22381 tcatttttat tatattttat cattcggtat aataaaatat aagttttttg ataaaataac
    22441 caaaaactac tcgctatccc ctctcacatt accctacata tcgtttgaca tgcgactgat
    22501 agttcaggaa aacttcaagg agaacttttc tctcatccac tatgcaggac ttactatttc
    22561 acttctactc ctataggctc aatttgacat ttttcttttt cgaattgctc atatgcctcc
    22621 tgaatagtga gttcgattta tccaaattta tttttgtcta ttttgatgaa tacttccacg
    22681 aagaatgaat ttgcaccaat tttccttctc tttttaagca tattattcca gatatgattg
    22741 ccctcttgtt cagtaataaa ttacgcttta aacgcttcaa tcagtatatc tcctgttgtc
    22801 atatgttcta aagaaaattc ttctacatat ggtttaacat ctcttaggtt attacttcct
    22861 aatatcccat tatgcttttt cgctaaggaa atagatgccc cttctccttt accaataatc
    22921 ttgttactat catgatttct tgttaaatct ctatataatg cgtattcttc agttccaatg
    22981 tctatgctca caatctcagc tgaaccctta gctaccaact gatctatcct agattttaaa
    23041 tggggaattg taggtatatt gatttcatca tacacctctt gtggaataac aattttaccc
    23101 aaatagagct tttctaaaag atgttcaatg ccaacccata aaaatactga aatacaatct
    23161 gcatcaataa atacacgact agtcaaacga caactccccc ctcttcatct agcccatata
    23221 caatatcata tctgaaagca tctagtaaca gttcctcata cttcccttgc gaaattctgt
    23281 tattttctaa aagttgttca gttgaattaa tatattatcc taatgccatt tcttttttac
    23341 tttctgacaa aggacgatat aaacttgtat catagcctaa tcttgaagct gtctctataa
    23401 cactaatatc catattttta atttcttctg catcaaggta tccatcattc ctcaatctat
    23461 ataacatagc tttatgactg ataccataaa actgacccaa ttttataata tcttctactt
    23521 caagatgagt tctattggca ttttctctga tttcctcaac catcctatac agtgaagatg
    23581 ggaaaattaa aaaataagaa gcaaactgat ccgcttttct ttcagtttca tctccttcac
    23641 caatcaagat aagactgact gaactcttct tcacctcatc ataataaaga tgatacagtc
    23701 catgtgctaa agaaaatctt tacctttcta atggcatgtc tgaattgact gcaatgagac
    23761 tgaactgagt tcctttataa cagactccgc taatattctt tccgagtcca taaaatacca
    23821 gcgtcaaatt ttctatcttt tgtaccaatt taaaaatatc tatcggcgat tcaccatcag
    23881 ctcccaactt ttttctaaga tttgaagctt tattacttaa atccattcgt gatattcctt
    23941 tcaccttttt ccattttggc aatcatgctt tgattcaaag acaaatactc agcaatctta
    24001 tcttgagtaa gatttgaaga tattctaagt tcttttattc tttttccaac atcacataca
    24061 tttatcacat acatttatca tattcataca cctctcataa aaagaatagc acactcttgt
    24121 cataattttt taaataaaaa aattatgaca aaacaaggaa gcaatttatt gatgctgctt
    24181 aaaaatctaa aattgatgag ttcctatcaa aaatcgtatc ttcaacctca aaacagtact
    24241 taaagctatc cgactcggtt tacattgtca aatttagatt ttatttgagc ataactttct
    24301 agtttgcttt ctgatttttg tttaatatag tagcaaacat tgaaggaaat atctccacaa
    24361 aaaaacgcat actattaagc tttttcaaga cctaataata tgcgctgttc tgatttgaaa
    24421 gacattccat tattatttta ctgtaatcaa gccatctggc tctactgtga attctggctt
    24481 gtctgccagt gttccgtctg gtttgaggta gtaccagcct gttccgtccg ctgactggat
    24541 aaaggcattt gataccatgg cgccttcttt agcgtctaag tagtaccaag tgtccttgta
    24601 cttgacccag cctgtcttca tggcaccttc ttcgttgaaa tagtaccact tatcagcgat
    24661 tttcttccag cctgtagcca tttcgcctga gttgtcgaac cagtaccagt tgccgtctgt
    24721 gtgcttcctc cagcggtctg caagcatata gcctgaactg tcaaagtagt accaagtgcc
    24781 attgattttc tcaaacttgt cttttggata agagccgtct gaatgtacgt accagtagcc
    24841 agtgtcattc ttctgccagc ctgtttcaat cgtcaagccg ttctcaatat catacttaaa
    24901 ctgctcacgg ctaatgcccc attttgccaa gtaagggtat ggatccacat ggtctgagtg
    24961 gttgtttggt tggttattcg tgcaatactc gtgcgtttta attccagcta aactccctgt
    25021 atcaagcgtt ttcggcaaac ctgcttcatc tgctagattg cgtaagagtt cgatataaag
    25081 gcggtaatcc gtcatgaact cttctttagt tgaatggctt tcaatcagtt caaccgctgc
    25141 ataggtctca gcattccaac cgcccccaac gtcccaggca ccattatcaa caggtcctac
    25201 ctgcatgatg caaccgttcc caacaatgtg cgagaaaaaa cctaattctg ggtctttccg
    25261 ccagtgataa tccgcttcat tctgtacggt tgaatgcgga ttcccagttg agtgtgcgtg
    25321 tacttgccta tatggttgca cgccgacttg aggcaaatct gttcttaatt tactcacatt
    25381 aatttccata ttctactcct tatcaattaa aacaactcat tttttacaat ccagaaccag
    25441 aaactccttt atttctacct tacaaagaag acaatcttag tcacgattag gcttgtagat
    25501 agaacctcaa aacgcactat tttgacactg taaataggac tgacaaggtc tgcattctat
    25561 ctacaataac accccagact aaaaagcttt tcaaaagtat atttttacag tctctatatg
    25621 tccttttcat aaatactata ctttattata tcatataaaa gaagtcaaaa gtctgttaaa
    25681 ctattttcaa caccaaacta aagaagagaa cacaagtttt ttcgatgttc actagaggaa
    25741 atggatttta ttcagtaaat ccaactagga ttgcactttg gttgccaaaa ttgcctttcc
    25801 ttcttttatc aagggatgac ggaatagtga gaagtacagt tgaactgtca tggcaaccca
    25861 gataagaggt tcacaaagga taacaccctt atatcctgcc caaggaataa tcaaaaccac
    25921 aaaaacgatt tttccgatta gttcaataaa gctagaaact agaggaagga tcttctgccc
    25981 caagccctgc aagcaattgc gataaatcaa caagaggctc aaaatgggat aaaaggctga
    26041 actgatttgc agatagagac ttccattttc tatcaagtaa ccatctgtcg aactagccaa
    26101 gaaggaaacc aaggctggac tggcaaaaaa gaggaaaata caaacaaaaa ctgcccagga
    26161 tatacttaaa cgactgccga ttcgaagacc ttgaacaatg cggtcaggtc gcttagctcc
    26221 tagattctga gaagcaaagg tcgtcattga tgcagaaata gcggtcatag gaagaagggc
    26281 aaaggtcata atgcgtcgag ctgccgtctg ggcactaata atcactgcac caaatgtatt
    26341 aacagaaaac tgtaaaatca cactgccgat agatacaatt gaactcatca agcccatagc
    26401 caaaccttgc tccaagagat ccgcgtacaa gcttttgtcc catttgaaat gtttaaaccg
    26461 tggcaagagt tctggcacac ttttacgaat ataataaaag cagagaaccg ctgataaacc
    26521 ttgcgaaata atggtagcaa gtcctgcgga ttgaactccc agatgcaatt gcgtaataaa
    26581 atagagatcc agaaccacat taaccaaggc agagaaaatc agaaatccca gggctgctag
    26641 actgtcacca atagaccgca acaagcctgc aaaaagatta taagcaaagc tgacacctac
    26701 acaggtcaca atcatagaaa tatattgata agattgagga agaatttctg caggagtatc
    26761 taagtattgc aagagaggat acaagccaag aaagcccagc aacataacta gaatgctcaa
    26821 aagagcacct aaaatccagg tggctgctac tgcttccttg attttagtga aattccgagc
    26881 cccataataa cgagcaatga caatccccat gccattgcca acaccaagtg taaaacctac
    26941 aatcaggtca aaaatcgctg tcgtcgctcc tactgcagcc aaggattctt gaccaagaaa
    27001 tcgtccaaca atcaagacat cagcagtgtt atagagctgt tgaaaaatat ttgatagcaa
    27061 gattggaaag gtgaagctta agagcgaggg aagaatcgaa ccatgtatca ggtccactgt
    27121 tcgtttttta ttcataaagc tattatatca gctttccaga ggagcgacaa gaaacagcaa
    27181 acttatatat agcggaatga aataaggaca gtcaaatcga tttttaacaa tgttttagaa
    27241 atagatgtgt actattctag tttcgatcta ttatagttgg ttgagtttgg aatagtacgc
    27301 tgtagctgct aaaacatttc tagaaattaa tttgactttc ctaataaagt tgttcatatc
    27361 ttatttcaag ctactatata taatctaaaa acttgaatca aaaatcgaaa aagtagcgga
    27421 tttttccact gctttaacag cttattcttc aatttcgatt tcaagttcat cgcctaagtc
    27481 aagcgtaact tcttcattca ctgcttcttc tttctttggc tcatcttttt tgttttcagt
    27541 atcttgttct gaaacttctt ctccatcaat caagccaaat ttagaacgga cttgcttatc
    27601 aatttcatca aagatttctg ggtgctctgc caagtatttc ttagcattct cagaaccttg
    27661 cccaattttt tcatctttgt aagaatacca agcccctgct tttttgataa tatccaaatc
    27721 gcttgcaatc ttcaaaagct caccagtctt agaaattcct tctccgtaca taatttcaac
    27781 tacggcttcc ttaaacggtg gagctacctt attttttaca accttaatct tagtttcttt
    27841 accgacattg gtttcttttt ggtcaccagt tcccttaatt tgtgtattac cacgaacatc
    27901 caagcggact gaagcataga atttcaaagc acgtccgccc ggtgttgttt ctggatttcc
    27961 aaacatcact ccaacttttt cacgcaattg gttgataaaa atggcaattg ttttggtttt
    28021 attgatagag gcgccaagtt tacgcatggc ctggctcatc atacgagcct gcaaaccaac
    28081 atggctatct ccgatatctc catcaatttc cgcacgagga acaagggcag caactgagtc
    28141 gactacgaca agatcaactg cacctgagtc aatcaatttt cccgcaattt caagaccttg
    28201 ctctcctgag tctggttgag acaagagcaa ttcgtcaata ttgacaccaa gggccgcagc
    28261 ataagctgga tcaagggcat gttccgcatc gataaaggca gcaatcccac cttctttttg
    28321 cgcttgtgca actgcatgaa gggcaaccgt tgtcttacca gatgactctg ggccatagat
    28381 ttcgatgata cgtcccttag gataaccacc tgagccaagg gcaatgtcaa gagctaaaga
    28441 acctgagctc atcacttgca ccttttgctc cgcacgttca cccaaacgca tgattgatcc
    28501 tttaccaaag tctttctcaa tcaatttaag agcgtcattc aaggcctttt cacgttctgc
    28561 cccaaatttt tttgaaattt cttctaattt ttttggtttt ttcgccattc tattctccta
    28621 cattctaatg atcctcagac ctatctacta ttatatcaaa agttagtcac ttaataaagc
    28681 cttgcgaact aggttaaagg catgcataac cgcaatatga cgtacatctg ctcggcttct
    28741 gcctccaata ttaaccttga taacctcagt tccttgctct tgcgccaagc ctatgaagac
    28801 tgtcccaact gggtgtcctt ctaggctatc tggtcctgcc actccggtca aactaattcc
    28861 aaaatcagac tgggtcttgc ttcgtgcctg ctcagccatc ttctgagctg taaattcaga
    28921 caccacacca tgttcttcca aattcttggc aggaatatcc aacatccttg atttttcctc
    28981 caagctatag gtcacaaaac cacccttaaa tatacttgaa actccagaaa aattcgccac
    29041 ggtagcttgg aaaagacctg ccgtcaaact ctctgcagcc gcgatggttt tcccttgcct
    29101 tttcagttct tctaccacaa tgctggctaa actagtttct tccccataac catagcaaaa
    29161 gtctcgtaaa gaaattcctt cgaaagtctg gcagtccaag atttgatttt ccaagatatc
    29221 cagcgcttga ttcgcctctt cttgactgct agcctttgtt gacagacgta gagtgacttc
    29281 tcctgtcttg gcataagggg ccaaggtagg atcgatctga ttatcaatta aatcagccaa
    29341 aatcgtaacc agctggctct cgccaatccc aaagaaacga agaactcggg aatacagctt
    29401 gctccctgtc atcaacttgg gtagaagttg gtttaagacc atgggtttca attcacttgg
    29461 cggacctgga aggacgacat aggtcactcc gtctacttct aattttcctc caacagccag
    29521 tcctgtttcg tttggcagtg gaatcgctcc ttctacaatt tgagcttgtc tttcgttatt
    29581 cggtgttcgg gcatagtctg gtcgcagggc aaaaaagata tccaacttct cctgagcctg
    29641 aggatcaaag actaatgctt tccctaaaaa tttagctagg gtttgtttgg ttaggtcgtc
    29701 ctcagttggc cccaaaccgc ctgtcaaaat caccagactg ctacgttgac tggcaatctc
    29761 aagcaaagac aagagacgaa cttcattgtc tcctacagcc gtctgaaaat atacatctac
    29821 cccaatctca gctagttttt ccgacaaaaa ctgggcattg gtgttgacaa tctgtcctgt
    29881 caaaatctct gttccaacag caatgatttc tgctttcatg tttcctccta cctatctatt
    29941 cgtatttttt tgaaaaaatc gcaggaattt tcctacgatt gattttttta tttgtatcaa
    30001 aagttaatta tcttcatcac caacaggtgc tctgccaaat aaatcttcaa ataaaaccgc
    30061 attggtttca agctgagtaa cttcttcttg tcccaaagaa cgtcggagta tattttgcat
    30121 ttccaacata tgtgctctcg aaacaatctg gtaagaaaca ccttgaagta tctctccttc
    30181 accctgcaac tgctgagttt caatggtttt aaatgaatct ttatagccta gcaagttagg
    30241 gatacttttt gcagacaaat caatattggt ctgcatattg tcactcaaag cttttagaat
    30301 ctcttgataa tgaccaatgc tatttaaact gagagctttt tccatgactt tttgaataac
    30361 ttcacgttga cgtttttgac gaccataatc cccctcagga tcttggtaac gcattcgtgc
    30421 atagactagg gcttcttctc ccccaatatg ttgctcccca acaccgatag aaatggtatt
    30481 aaattcttct tggtcactga tagaaattgg gaaacctagg atattattga ctgtaatacc
    30541 tcctactgca tccactaatt tttgcaaccc tctcatattg accatcacat agcgatcaat
    30601 atggatattc atcatttttt gaatggtttc tatagcaagc tctgctccac catctgcata
    30661 tgctgagttc agtttcgctt catgagcctg accattccct gattcaatgc gcgtcagaat
    30721 atcccgctct aaactcatca ttgttgtttt tttcgtttta ggattcactg tcatcaagat
    30781 catgctatca cttctaccga cccaagtttc agttcgttca acatttccgg tgtccactcc
    30841 cattaacaga atggttagag gttcagtcgc ttcaataacc ttggtttctt cgccgatttt
    30901 tttataggtt ttagctaagg tttctgtccc ttgttgataa atagtataag caaaaacacc
    30961 tactcctact acagttacag aaagtaaagc tagcaccatt ccaataattt ttttaaccat
    31021 atttctacta acctatcagt ttacccatca agtaaacatc gataaatttc ccttcttcta
    31081 tatatgcccc acgctcttgg ctaccttcaa tgacaaagcc atgcttttga taaagatgga
    31141 ctgctgcttg attacgagtt tggacagtca gttggagacg acgcagaatg ccacttgctt
    31201 gtgcccactc tatcgcttct tctagcaaca aacttcccaa gccattattc caatatcttt
    31261 ttccaatcac aatgaagaga tctccaatat gacggactct cttacgctga tcagctgtaa
    31321 tatttacaat accagtaatt ttgccattta agaatgcaag taaggttatc tgattgtccg
    31381 aactagcttg cttgttgagg aatatttcca tctcctcact agtcaagaga ataccatctc
    31441 cgtctaggct ggtaaagtct gtctccaaac tcacacgatt taaaaaggcc actaattcag
    31501 ctgcatcttt gggctctgct tccctaatga gcaattcata ctccatattg aagctcctct
    31561 gacaatttct cagcacgcaa accctttgcc tgaaaattta aacggcgtcc atctgcttct
    31621 tttagaattt ccaattctaa ataagcatct ggcaaggcat ctcctaagag atttccccac
    31681 tcaataacag tcacgccgcc accaaagata aactcatcca agtcgataga atcagcatct
    31741 ccttcaatac gataaacatc taggtgataa agtggaagtc gaccttcata ctctctcacg
    31801 atagtatagg taggactttt aatcatttga gaaatctgta atccttttgc aagtccttta
    31861 gtaaaggtcg ttttacctgc acccagttct ccaattaaga ttaaaacatc attctttgct
    31921 aatagatggc ccaaacgctc ccctaaggct tgcaactctt cttcattttt tatgtacata
    31981 ctcttattat accaaaaact tttcttttgt gtctattttc ctactaaact tatcatcata
    32041 acatccataa aaaacaggct ttctctaaaa gaaaatgagc gtaacaatga ccaatacaag
    32101 atctcggaaa atatgaccat aaaaggaaac ttccttctta accgaatttg ggacaagata
    32161 ggctgcaaaa aacaagccca gtccaatata aatcagaagt gagacaatgg tcattggatt
    32221 tcttaagaaa agaagtgttg ctaaaatagt caccaacact gtcttttttc tgtccagcat
    32281 agcaagaaaa tcgcgcacgt attttttcaa gggtaaaaaa atcagcaaat ctagcccaaa
    32341 taggaaaaag aaggatggca ataaaaagtc aactaattct tgctgcagcg tatttttgat
    32401 gaacaagtta tctgacaaaa caagaacagc tcctaacaaa ttaattaaga gtaacatact
    32461 gtaaaaaagc ttcaccgact tcttactggc taggacacta tggacttctt gcttacgagt
    32521 ataaagataa tttactccag cacagattcc tgaaacgaaa accatgcttc cgatgaaaaa
    32581 agctgtactt tgtttaaagg acaagatgca ttccttccat aggaaacagc tactcaaact
    32641 gatttgaatt aaagctaaca aaaataagat tctcattgat ttcatcttct ctctcccttc
    32701 ctaccaatca ttatactagg agaaaagaga gaactgtttc taatcttctc aaatgtctct
    32761 ttaagacgct aaacaaacac tagagactaa tactcaatga aaatcaaaga gcaaactagg
    32821 tagctagcca caggttgctc aaaacactgt tttgagattg cagatagagc tgacgtggtt
    32881 tgaagagatt tacgaagaat ataaatttga aatcatgaaa atccgtcaaa cgggtggttg
    32941 ttttgtctcg cacctcacgg agcgagacgg actcagagtc acataattat aaggctgata
    33001 gtattaatct aactatcagc cttacaggtt atttaacgtt tcagaaaaac tataatgtca
    33061 agattaacta aacagtatct agttccttca aataattttc tatcttcatc aacattaaag
    33121 gattgttata aatcttacat aactctcttg cttctatata ataatttttg acttgttctc
    33181 tgtctagaaa tttggctcca gcatttccta caagaataag tagaggagcc aattggtagc
    33241 ttgtctgtct ttgtttacag agttcaatcg tttcaagagc ttcttggatg gcttcattat
    33301 atttttcctt tgatactagg tagtgagcgt agttgtaacg aactctgatg tagccaaata
    33361 aaaactcttg atggtccaaa ttttttgtct gatacaactc tattaaatga gagtagtttg
    33421 cctcatattc ttgttcacga cccactaagg aatagaaatt agatagagta ttcaacgcct
    33481 ttaaataaat cagagtattt gaagagactt ttaataatat attttccaat gaagaaattg
    33541 cctcacactt actgtcatat tgatagaagt caataatagc tttaatccat tcaaggtaag
    33601 ttcggtcttc tagtgttaga aaagtacttc gttcaatctc tattctataa atatattcca
    33661 aatcgtcata atttctatcg tctaatagtc gagcagacaa ttgcttgaaa ttagagaggt
    33721 tagatttaat ttcaatttgt tcattaaaaa aataatctaa tggtacttca agtcgttgag
    33781 agagtttgaa caaaaggtct gcggagggaa tgaaatgccc tctctcaatt ttactaatct
    33841 gactttgttc acaaattcct tctgcaagag tttgttggga gagtctcaac tcttttcttt
    33901 tcaatctgaa tttctctgcg agtgtattca ttaaagataa taaaccttcc tatttgctta
    33961 attgcattat aaaattttta gttcaaaata gcaagttaaa agaataaata attctttatg
    34021 gtaataaact aaaaaaagtc aaaaattaca taaaaatgct tgaccgaata atatatatat
    34081 attaaaataa aaacaaggaa aaagaaaagg gtttcacgaa tgaagaaaaa tcgtggaatt
    34141 caaaaattag ctatattagt attactaggt gtttttatgc ttagtaacac aattccttac
    34201 caacagttta ttcagaagaa tagacaattg gagattcgag tccaatcaca aaagaagtcc
    34261 aatggtcttg atgttgggaa ggctgattga tttcgtatta ctttaaaatt caactattta
    34321 gagaaaggta ttctgatgag agcttgtaac aataccagat agatattagt aagcttgtta
    34381 gtttatagag ggcaggggta tttctgccct ctgttttaga ataaggaatg cactatgaaa
    34441 aaattattta tactcatatc caacctgctt gctagtttgt tctttgtttg ggtatttacc
    34501 atttggactg atacatatgt ctcctattat taccccaacg ttgttgtaca tgattcttcc
    34561 cctgaaacaa cttttcagca tgttgctaca cgcttggaaa aactagcaga agaaacagat
    34621 agctttattg cgattcaaca ccaagattct aactcagaag gtactacagt tttttcttat
    34681 acgacctttg gggacggaaa gttgcctgat gggcttcagg aaaaaaaact agaagatgct
    34741 caaagtagta gtgttgaaac aaactatttt gtattcgatg gacacctaga tattcacttg
    34801 ctaagggagg agctaagtca acttggcttg actaacatga acctgacaat tccatctaaa
    34861 ctatctacgt taatggctat ctttagtaac ggatttcagt taatcagtct attgattttc
    34921 atcttaacct ttgtagcact gactttaatt agtcaaatta gccaattacg gtcgtcgggc
    34981 attcgcctca tttcaggaga gaaacggtgg tccattttcc ttagaccagt tggtgaggat
    35041 ttgaaaggga tagctgttgg tttcagttta gctggcgtgc tcgccattct tatgcaaaaa
    35101 attctgtcgc ttccaacgca atccctaatg accataggag caggcttgct cagttataat
    35161 ctcatcttgt tgtcgatctc cctgtttttc gctcaactct tcgcagttgg gataaaaaag
    35221 atacacctga tgcagattat aaaagggcaa gtgcctgtca gaggaatcat tagtttgatt
    35281 ttaatcggtc aactattagc gattattatt gtaacgctgg gaatagggag tagcttaaag
    35341 tattcccaag cctggcaaca gcatcggatt ggacaagagg cttggagtca ggaaaggcaa
    35401 ctgattaccc tatcaatcag ccgtgaagga acgagtcctg gttttgatga acaagctcaa
    35461 aggaaactca gaacttggta tcaattgatg gatctggctg tttcagaaca aaaggctttc
    35521 ttatctagac accagttaat tgaccgtact ttgcaaaatg gcatggcttc ctccaaaaac
    35581 ttgataacct ctacagaatg gcacgattac aacccgaatg gcaatgtcct tatcgtcaca
    35641 ccgcaatact tggagcgtca aaacattcct gtagatacaa ctattgagca aaagatgaat
    35701 cacctttatg taggggagtt tgtcttattg ctgcctgaac acctccgttc agaggaagaa
    35761 cattataaat ctgtttttga agacgactta accagtcgca tgtctagtca agatgaacga
    35821 cagcaaatga ctgctacggt aggttattta gaatcaggtc aggatcgttt tgtgtataat
    35881 acgaccccta tttcttacca gcagtttttg aaagatccaa tcatcattgt tataacaccc
    35941 caatcaactg gtccacagtc cattttgttt tggatagacg cagtacagaa ctacgttctc
    36001 tttaatcaat tgtctgatgc ccaggagctt atccagagac aaggcattga aaattgggtc
    36061 tcagaaatgc aaacaggtta ccacaactac atcacattat tggataatat tcagagggaa
    36121 cgttgggtaa tgctagcagg agctgggctt gggattgcaa cttcaatctt gttgtttaac
    36181 actatgaata ggctctactt tgaagaattt agacgtgcca tttttatcaa acgcattgca
    36241 ggtctcaggt tcttagaaat ccatcgcact tatctctttg ctcaactggg tgtgttttta
    36301 ctgggatttg ttgcgagtgt atttcttcag gtagagatag gagttgcttt cttagtcttg
    36361 ttactcttta ctggtctatc tcttttacag ttacatgtcc aaatgcagaa agaaaacaag
    36421 atgtccatgc ttgttttgaa gggaggttaa tatgattgaa cttaaacagg tgagtaaatc
    36481 ttttggagaa cgagagttat tttcgaatct ttcaatgaca tttgaggctg gaaaagtcta
    36541 tgccttaatt ggttcaagtg gtagcggaaa aacaaccttg atgaacatga ttgggaaatt
    36601 agaaccttat gatgggacga ttttttaccg aggtaaagac ttggccaatt ataaatcgag
    36661 tgattttttc cgtcacgaat tgggctacct cttccagaac tttggcttaa ttgaaaacca
    36721 aagtattgaa gaaaacctta agctaggtct cattggtcaa aagttgagtc ggtcggaaca
    36781 gcggttgagg cagaagcagg ctttagaaca ggtcggcctg acttatcttg acctagataa
    36841 gcgcatcttt gagttatcgg gcggagaatc gcaacgggtt gccttggcaa aagttatctt
    36901 aaagaatcca ccctttattc tggcagatga gccaacagct tcaatagacc cagcaacttc
    36961 tcagttgatt atggagattt tgctatctct tcgagatgat aataggctaa tcattatcgc
    37021 aacacataat ccagcaattt gggagatggc tgatgaagtg ttcacgatgg atcgtctgaa
    37081 ataaaaatcc ttgtttttaa ttgcacgatg agttactgaa atattatcat gaatcaataa
    37141 ttggagttaa tttagaattg tactttatta atattgaggt aactttttct tgataaagga
    37201 agaaatagtg gagaggaagt tagaatgaaa aaattcgaca attatattgt tgagaagcct
    37261 tgcgattcta attcagataa actgcaaaaa atcttaataa ttgaaaattt ggtagatgat
    37321 attttgcaat ttcctctcag aatcaataat agtgtaggag agattttcct cctacaaccg
    37381 tttcaaaaga aaactatctt tattccatgt tattttgagg aagatattgt gaaagtcaaa
    37441 gatgatgata aagttgagtg gaatttgtta gaatttcaaa aatttagagc atttttggct
    37501 tagtaatctg tgttgaaggc tcaaaaccta tggtaaaaaa gtcgctttga aaacgtattg
    37561 cctccaaaga tttagttaaa taatgattta acacaaaaag aaattattga agttctggaa
    37621 agatgttgtt tcagtattga gaaaaggtgg gaaaaacttg cgattttcac agagaaagga
    37681 agaaaaagta tagaaatata gtcaattgaa acaagaacag gacaaaagaa ccttttgtgc
    37741 catatttttc tcctttcgct ttacaattgg cttgaacacc tttattgtat cgcgtttgga
    37801 gtttttttgg tataaccttc gacgcgcacc cgcatagcgg gtgttttttt gtctcgcacc
    37861 taacggagcg agacgaacta atagtcactt aatcaaaaaa cgcaccatat caaaaactaa
    37921 aaagtttgat atcatgcgtc atgtcttaaa ctaattgact atactttcta ttcaaatgag
    37981 cttttaacca attgattgag ccaatccact cttaaaacca aagagcaatt tctcgcttag
    38041 ctgactcttc tgaatctgaa ccatgtacaa cattttggat aacctcattt tctccagcag
    38101 cttttgcaaa atcacctcga atagtgcctg gtaaagcttc ttctggacga gttgcaccca
    38161 tcatggtccg ccaagtttcg attactttgg gaccagaaat gacacccaca agaactggac
    38221 ctgaagtcat gaattcacga atcggtgggt aaaaactctg accaaccaag tcctgatagt
    38281 gctggtcaat caactcttct gaaacttgtg aacgaaactc caatttttcg attgtaaatc
    38341 cacgttgttc gatgcgcttt aacacttcac ccactagccc tctttttaca ccatctggtt
    38401 tgatgataaa gaatgtttgt tccatacccg tctcctttgt cagcttcttt cttttatttt
    38461 accacatttc gtggaaaaat ggagaaagtt ttcagaatag agaatgagag aacccgaggg
    38521 ttctctcatt ctctattatt ctactgtttc ttccacagtt tcaacggcag tatccacaac
    38581 tacttctgtt gtttcttcat ttccttcttc ctctactgga ggattaaggt attcttcttc
    38641 gttgacagca tatggttcaa ggttacggta acgggccata ccagtaccag ctgggatgat
    38701 cttaccgatg ataacatttt ctttaagtcc aaggagatgg tctttcttac cacggatagc
    38761 tgcgtcagta aggacacgag ttgtttcctg gaaggaagcc gctgacaaga aactgtttgt
    38821 ttcaagtgag gctttggtaa ttcccataag gactgggcga cctgtcgctg gaactccacc
    38881 tgcgataagg acatctttgt tggcatctgt aaagtcattg atatccatga gggtacccat
    38941 gagaagatct gtatcacctg gatccatgac acggacttta cggatcattt gacgaaccat
    39001 tacctcgatg tgtttgtcac cgatttctac cccttggcta cggtaaactt tttgtacttc
    39061 accgagaagg tacgtttcaa ctgacaagac atcacgaact gcaaggagac gttttggttg
    39121 gatagaacct tctgtcagag cagcaccacg cgctacttgg cccccaactt cgacacgcat
    39181 acgagctgta aatggaacga catattcacc ttcgccagtt tcacccttaa caaagacttt
    39241 cttggtacga gttgatgcat cttcttcgat agcagtaact tgtcctttaa cctctgtgat
    39301 aaccgcttcc cctttaggat tgcgggcttc aaagatttct tggacacgag gaagaccctg
    39361 agtgatatcg gtatttgagg caaccccacc tgtgtggaag gtacgcattg taagctgtgt
    39421 accaggttcc ccgatagatt gggcagcaat ggtaccaact gcttcaccaa cttcaaccgc
    39481 atcaccagtc gccaagttga taccgtaaca gtgacggcag acaccgtgac gagtgttaca
    39541 tgtaaataca gaacggatag tcacttcttc cacaccagca ttgacaattt cacgcgcctt
    39601 gtcttctgta atcaattcat ttggaccaat aatcactgca ccagtttctg gatgtttaac
    39661 agttttctta gtgtaacgac cgttgagacg ctcttcgaga gactcgatca tctcttttcc
    39721 ttctgcgata gaacggatca agagaccacg gtcagttcca cagtcgtcct cacggatgat
    39781 aacgtcttgg gcaacgtcga ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag
    39841 ggccgtatcg gtcatacctt tacgagcacc gtgagttgag aagaacattt ccaataccga
    39901 caaaccttcg cggaagtttg aaaggattgg caattccatg atacgtccat tcggagcagc
    39961 catcagacca cgcataccgg caagctgtga gaagtttgag atgttaccac gggctccaga
    40021 gtccatcatc ataacgattg ggttcttagg atcttggtta gcaatcaagc gtttctcaag
    40081 tttttcacgg gcagcacgcc attcagctgt aacagcattg taacgctcgt cgtctgtgat
    40141 cataccacga cggaattgtt tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat
    40201 ttcagtcttg tcatcaacga ctgggatatc ggcaataccc actgtcaatc ctgcaagagt
    40261 tgagtggtgg taaccgaggt tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg
    40321 gaaacgtttg aagatttcag cgatgatatt tccaaggttt ttcttcttga atggagggtt
    40381 gagctcaaga ttgctgatag cttccttgat atctccacca agtggcaaga agtatttagc
    40441 tggaacacct tctgtcaagt tggcattgtt tggttcttgc aagtatggta gcccctctgg
    40501 catgatatcg ttgaagagaa ttttaccaac tgttgtaagc aagaccttat gtctttgctc
    40561 ttctgtccaa ggcttgttga ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac
    40621 ataaccattg cggtaagcca taaccgcttc gtcacggtct ttgaagacca ttccttcacc
    40681 ttcgcgacca gcttcttcca tggtcaagta gtagttaccc aaaaccatgt cctgagatgg
    40741 agtaactacc ggtttcccat ctttcgggtt caagatgtgc tcagcagcta gcatgaggat
    40801 acgagcttct gcttgtgctt cttctgaaag tggtacgtgg atggccattt ggtccccgtc
    40861 aaagtcggca ttgtaggctt cacagacaag tgggtgcaag cgaagagcct taccatcaat
    40921 taagactggc tcgaaggctt ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag
    40981 cactgggtgt tctttaatca cttcttcaag gatatcccag atacgctcat ctccgcgttc
    41041 caccaagcgt ttagctgctt tgacgttttg cacgatatca cgggcaacga tttcacgcat
    41101 gacaaatggt ttaaagagtt caatcgccat ttcacgtggc acaccacatt ggtacatctt
    41161 aagagttgga ccaacggcga taacggaacg tcctgagaag tcaacacgtt taccgagcaa
    41221 gttttgacgg aagcgtcctt gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg
    41281 gctacctggt cctgtgattg gacgaccacg acgaccattg tcaatcaaag cgtcaactgc
    41341 ttcttgaagc atacgtttct cattttgaac gatgatacct ggtgcattta actcaagcaa
    41401 acgagccaaa cggttgttac ggttgataac acggcggtaa aggtcattca agtcagatga
    41461 ggcaaaacgg ccaccatcca actgcaacat tggacgaaga tctggtggga taaccggaag
    41521 gatgttaaga atcatccatt caggtttgtt tccagacttg taaaaggcat ccaaaacatc
    41581 caaacgacgg atggctttga cacgtttttg tccagtagct gttttcaatt cttctttgag
    41641 ttcagcaatt tctttttcaa gatctacttg cttcaaaagg tcttggatgg cttccgcacc
    41701 catcttggca acaaatgaac cataaccata ttcgcgcaag cgctctcggt attcgcgctc
    41761 tgtcatgata gacttgtgct caagtggtgt atccttagga tcaatcacca cataagccgc
    41821 aaagtagata acttcctcga gggcacgagg gctcatatca agggtcaagc ccatacggct
    41881 tggaatcccc ttgaagtacc agatgtgaga tacaggagct ttcaattcga tatgtcccat
    41941 acgctcacga cgaactttcg tacgcgttac ttcaacccca cagcggtcac aaacaattcc
    42001 tctgtaacga atgcgtttgt acttaccaca agcacattcc cagtcttttg taggaccaaa
    42061 gatcacttca tcaaagagtc cttcacgttc tggtttcaag gtacgataat tgattgtttc
    42121 aggttttttg acttctccat aagaccatga acggacttta cttggagaag ctagggtgat
    42181 ttgcatactt ttaaaacgat ttacatcaac cactatttct tccctttcta ttctaagtga
    42241 actgcttatt cttgttcagc agcttcttct gttgcttccg cttttgttgc tttctcagct
    42301 tcttcagctt caaaggctgc tttagcctct tgggctgctt tttcgcgggc tttttcaagg
    42361 tcatctacgt ggatgacatc ttcgtccatt ccttcatcca agtcgcgaag ttccacttct
    42421 tggtcatctt cgtctaggac acgcatgtca agaccaagag attgcaattc tttgacaaga
    42481 actcggaagg attctggaac acctggtttt ggaattggtt tgccttttgt aatagcttca
    42541 taggctttca aacgtccgtt gatatcgtcc gacttgtaag tcaagatttc ttgaaggaca
    42601 tttgacgcac cgtaggcttc aagagcccaa acctccatct caccgaaacg ttgtccacca
    42661 aactgagcct tacctccgag tggttgttgg gtaacagttg agtatggtcc gactgaacgc
    42721 gcgtgcaatt tatcatcaac catgtggtgg agtttgatca tgtacatgac tccgacagaa
    42781 acacggttat caaacggttc accagtacgt ccatcgtaaa ggatcgtttt ggcatcgcta
    42841 tccatacctg cttctttaac agttgaccaa agatcttcag aacttgctcc atcaaagact
    42901 ggtgtcgcga tgtgaatacc aagagtacga gctgccatac caaggtgaag ctccataacc
    42961 tgaccgatat tcatacgtga tggtacccca agtgggttca acatgatgtc gactggagtt
    43021 ccgtctggaa ggtaaggcat gtcttctaca ggaacgatac gagagacaac ccctttgttt
    43081 ccgtgacgtc cggccatttt atctccgacc ttaatcttac gtttttgagc gatgtaaaca
    43141 cgaaccaaca tgttaacacc tgattgcaac tcatctccat ttacacgtgt aaagatctta
    43201 acatcacgaa cgacaccatc ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca
    43261 cgagacttgt ctccaaagat agcgtgcaag agacgttctt cagctgaaag atctttctca
    43321 cccttaggtg ttactttacc tacaagaata tcaccttctt taacctcagc accaatacgg
    43381 ataatcccca tttcgtcaag gtctttgagg gcatcttcac caacgtttgg aatttcgcga
    43441 gtgatttctt caggcccaag ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga
    43501 acagatgtgt agacatcgtc cttcaccaag cgttcgctca tgataacggc atcctcgaag
    43561 ttgtaacctt cccaagtcat gtaggcaacg attgggtttt gtccaagcgc catttctcca
    43621 ttttccatag aaggtccgtc agcgatgaaa tcgccttttt caacgacatc accaactttt
    43681 acgagagtgc gttggttgta agcagtacct gagtttgaac gacggaattt ttggatgtgg
    43741 taaacatcca atgaaccatc ttcacgacga acttctacct tgtcagcatc tgcgtaagta
    43801 actttaccat catactgagc aatcacagcc gcaccagaat cgtgggctgc ttggtattcc
    43861 ataccagtac caacgtaagg tgcctgagga ttaatcaatg gcacagcctg acgttgcata
    43921 ttggctccca tgagggcacg gttggagtca tcgttttcca agaaaggaat acatgctgtc
    43981 gcaacggcaa ctacctgttt tggtgaaacg tccatgtagt caacaatatt agctggatac
    44041 tcttggttga ccccttggtg acgtcccatg acaatcttct cagcaaaggt tccatcttca
    44101 ttcagacgag agttagcctg agctacagta tattcatctt cttcatcagc tgtcaaccaa
    44161 acaatttcgt tcgtgacaac acctgtttca cggtcaacct tacggtatgg tgtttgaaca
    44221 aaaccatatt tgttcaagtg tccgtaagat gacaagttat tgatcaaacc gatgttaggt
    44281 ccttcaggtg tctcgattgg acacatacga ccatagtgag tgtagtgcac gtcacgtact
    44341 tcatatccgg cacggtcacg agtcaaacca ccaggtccta aggctgacaa acggcgtttg
    44401 tgagacaact cagaaagcgg gttgtgttgg tccatgaact gtgacaactg tgatgaacca
    44461 aagaattctt taactgcagc tgttacagga cggatattga taatttgttg tggtgtcaag
    44521 acttcattgt cctgaacaga catacgttca cggacattac gttccatacg agaaagtccc
    44581 aaacgtactt ggttggcaag caattcacca accgcacgga tacgacgatt tccaaggtgg
    44641 tcgatatcat ctacacggcc aagtccttca gccaagttga ggaagtagct catctcagca
    44701 aggatatctg caggagtcac cgtacgaacc ttgtcatctg ggttagcatt accaatgatc
    44761 gttacgacgc gatctggatc agttggagca acaaccttga atttttgaag aacaacaggc
    44821 tcagtcacaa cggctgcatc gtttgggatg tagacaatct tgttcaagtc gccatccaaa
    44881 tggctttcaa tgctttcaat cacgctacga gtcataatcg taccagcttc taccaagatt
    44941 tctccagttt cagggtctac caatggctct gcaatggttt ggttgagcaa acgtgtttta
    45001 acattgagtt ttttattgat tttgtaacga ccaactgctg ccaagtcata gcgacgtggg
    45061 tcaaagaagc gagccacaag caagctacgt gagctttcag ccgtcttagg ctcacctgga
    45121 cgaaggcgtt cgtaaatttc tttcaaggct tcgtctgtac gagagtccat tggattcttg
    45181 tggatatctt tttcaacagt gttgcgaacc aattcgctgt caccaaaaat atcaaagatt
    45241 tcatcatcac ctgagaaacc aagagcacga accaaggttg taaatggaat cttacgagta
    45301 cggtcgatac gagtgtaggt gatatctttt gagtcgcttt caagttccaa ccaagctcca
    45361 cggttaggga taacagttga accatagccc accttaccat ttttgtctac tttgtcgtta
    45421 aagtaaacac ctggtgagcg gaccaactga gaaacgataa tacgttcacc accattgatg
    45481 atgaaagtac ccatttctgt catgattggg aaatcaccaa agaaaacttc ttgggtcttg
    45541 atttcgcctg tttctttatt gatcaagcgg aaggttacaa aaattggtgc tgagtagcta
    45601 gcatcgtgaa tacgagcttc ttctagcgtg tattttggtt ccttgatttc atatccaaca
    45661 aattccaact ccattgtgtc tgtgaagttt gaaattggca atacatcttc aaacacttcc
    45721 ttaagaccgt ggtctaggaa agctttgaat gagtcagttt gaatttcaat caaatttggt
    45781 aagtcaagaa cttctttgat tcttgaaaaa ctacgacggg tacgatgttt cccgtattga
    45841 acgtcatgtc ctgccaagat gattctcctt tgtaaataag ttccaagcct tgtcaatcag
    45901 gcttttctaa tcgccatatg gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt
    45961 cagaatcttt aagcctctgt tacaaatgct caaaatcttg aaaaaaagca caaaaagagc
    46021 agctaaatct gactttttca gaagatttaa ctgctgtgag ccttgtctgg acaatatttc
    46081 agacaaaacc tacgacaaat gattacccat attataccct atttagctag atttttcaag
    46141 gggattcagt aggtttttgg taattttttt cccatagaaa acttggcatc acattcgaat
    46201 cacgctatgg tacaaaaaac tgaaaaaact attgactgaa aatcattttc aaggtataat
    46261 aataaacgtt aaggcggtat agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt
    46321 cggttcaaat ccgtctaccg ccttctataa cttgatttat caggtttcaa atgaacagaa
    46381 agcccaattt gaagggcttt ttttattttc cctcgaataa atacgtataa ctttaaaaac
    46441 ttttggagcg agtttgtggc agagttcttt ccatggcata attccctttt gaaatcaatt
    46501 gaaaaaagct tcgtcacgcc tggtgacaaa agcctctagt ttattctgtt tcttcttcta
    46561 tttcgacttc tgtgatttgg acttttacct tggtaacacg tccattcttc actttatcat
    46621 tggttaagat aaactgtttg ttttggctga ccaattcata gctgagtttc tcagtcgttg
    46681 gaatggttcc cactcctgtc aaataataac cagcgatggt atcaacgtca tcactttcca
    46741 gttcaacatc aaagtaatta ttgaaatcat tgagggtcat agttccttga acaatgtagg
    46801 tatcctcgcc aatctgatga acatctattg ctgctttgtc cgtttcatca tcaatttcac
    46861 caacaatttc ctctaagagg tcttccaaag tcaccaaacc agccatacca ccgtattcat
    46921 ccagcaagat tgccatttgt ctttgggtat ttcgcagttc ttttagcaag tcatccacaa
    46981 aaatagtttc aggtacaaaa agtggatctt gtaaaattct cttccaaaca atattgtcaa
    47041 aaccgtccac aaagcctgcc ttaaggagac tcttggtgtg aatgattcca attacattgt
    47101 ccttatcccc atcataaacc gggatacgag aataattttg ttttaaaata ctttggataa
    47161 tggcttgact atcatcctga atatccacca taaaggcatc cgttcgaggc accataacct
    47221 ctcgtgccat cagttcatcg agcgaaaaga caccttgtag catctcaatc tcatcagcat
    47281 ccaatgtttc ttcactattt gtcagcatat aggcaatttc atcacgggtc atcttttcat
    47341 ccgcatcatc gaatgacata ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa
    47401 gccaaacaaa aggactgact agttttccga tcccaatgat aatcggcgct gtacgaattg
    47461 ccaaggcatc ctttagatta agagcgattc tcttaggata taattcccca aaaacgatgg
    47521 aaatataggt caaaaatgcc aaggatagaa aagttgccac ggcttgtgct gtttcgccat
    47581 tcccaagcca agaggcaatc acacgtccta gagtatcagt taaactcgcc cctgataaga
    47641 ttgtaatcag ggtgattcct acctgaatgg ttgataaaaa gtggttagga ttttctagta
    47701 ccttcagcag gcggatgtag cgtctgtctc cttcttccgc cttttgttca actcgggcac
    47761 gattaagaga aaccatggcc atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga
    47821 taaacaataa aacaaattgt agcaacaaat tctgactact tgggtcttcc atagttcttc
    47881 tcctaaaata gtatcttatc ctttattata tcacaaaatt taatccaata catattattt
    47941 ttttcttagc gtaacttcca tctctctccc aaaactggaa gttagtctaa gacggatttc
    48001 cactgatttc acgcgttttt ctcatactaa aagctaggtt gtgggaaact ggaagttagt
    48061 tttagaagtt actatttttt cttagtacct attctagccc tgcttaaact agtaaaaaga
    48121 actcctacat ccataagtga cataggagtt taggcttatc ttttactgag ttacagttac
    48181 ttctccagtt cggtaatcca gttgaagtcc cttttgaaca ttgggaacta gaacattgaa
    48241 ttccaattct ccatccgaag acttggcttc aatctgtgaa gctgagggaa ctaaatcctc
    48301 gtttgaagcg tagtaaaggg ttacacggta acggacacgc ttgttttggt ccaaggcttt
    48361 acgcaccttg ctttcatagt agttttgacc agtcgaatac tcggcttgtg cctgatttgc
    48421 ccaggctgtc tgaacagcaa tgtttttagg attgcttgtt gaggcatcaa aaccatccaa
    48481 accaccgatt aaggcatagc ctaacaaatg acctctatcg actgcatggg tataagagcc
    48541 ctttagattc ttgacctgat gccaacctgg aggagtccaa gaagttgaac cattcccagt
    48601 ttctttacga ttcttgtact gacgagtggc cttagacaag agggcattag ctacggttgg
    48661 aacagtttcc ttgcccactg tctttgtttt attgtcagcg tagggcttac ttgaaacctt
    48721 ggcatctaga tttgttttat taccattgac gataaaagca cctgagccat tccactccag
    48781 actccccttt atttgactct tgactgcgtc tgttaagaca ctctctgcca atgcttgact
    48841 aggagcttca gacgcttgtt ttttctgact aagattggtt ttgggactat taggtgccga
    48901 ctgcatctgc ttgatataat agctccctgt agacaaaagc aataacacta gcagtccgat
    48961 tagtgtctgt cttgtttttt tgttcatatt tctccttatc tttagaaaaa ggctggttct
    49021 ccagcctaat ttcctgtaaa tttatgaatc aattcctgcc attttgctgg agacaggata
    49081 gcccatggat cttgaccctt gcccaagatt ccataaccta ccattagacc gattcctaga
    49141 gccagagtac ctaaaatcag tactatgatg actaaaagta aacgattgat tacgtagctt
    49201 gatttcttat tcatcttcat cgcttgcctc aatccgctga atcttagcac ctagctgcgc
    49261 caacttctca tggaaaccgt agtaacctct atccaagtga accaatttac cgaccacagt
    49321 ttctccctgt gctaccaaac ctgtcaaaat caaggctgca ctggcacgaa ggtcagttga
    49381 aagaacttct gctccctgca aaggctgtcc accaacaata cgagctgtat cacggataat
    49441 ctcagaatgc aagcccatgc ggcgcatctc ttctaggtgt tggaaacgat tttcgaaaac
    49501 tgtctccacc atggttgatt cgccttttgc aactgtcatc aaggctgtaa attgagcctg
    49561 catatctgtt ggaaatcctg ggtggggcaa ggttttcaca tgaacagctt ttagattttc
    49621 tagttgagaa cgaacacgaa ttccttcgtc ttcttcaatt acttcaacac ccatttcaag
    49681 taacttggca atcaagggac ggttgtgctc ccagacagcg tctcgaatca agacatcacc
    49741 accagtcatg gcagcagcta ccataaaggt tcctgcttcg atacggtctt ggactacatt
    49801 gtgagtcgta ccatgaagtt tctcaacacc agtaatggtt atagtctctg taccagcacc
    49861 tttgaccttg gctcccattt cattaaggag aatggctaag tcaacaatct caggctcacg
    49921 cgcagcattc tcaatcactg tcaccccatc agccagagtc gctgccatca tcaagttctg
    49981 cgttgcacca acacttggaa agtccatata gatatgagcg ccatgcaagc gttctgcctt
    50041 ggcttcgatg taaccagctg tctgactaat cttaaccccc atagcttcca gacctttcaa
    50101 atgaagatca ataggacggc taccaatcgt acaaccacct ggcatggata ccttggcatg
    50161 acccacacgg gcaaggattg gccctaatac aacgatggag gcgcgcatct tgctgacata
    50221 cttgtaaggg gcttcctcag tgatgtcgcc agtagcatcc accttgacaa gatgagcttc
    50281 ctcatcaaag tcaaccttgg cattcaaacc accaactacc tgattcataa taaagacatc
    50341 cgacaaaatc ggaacattct gcaagacggt ctttccttca cttgctagaa tagtcgctgc
    50401 caacaagggt aagactgcat tttttgctcc ctcgatcgtc acgcttccta ccagacgatt
    50461 atcgccacct tgaaccacaa ttttatccat actcgtttcc tttactcttg attttataat
    50521 aatcctctaa gcgcttcttg ccacaaatga tacaggctaa taaagaaaga actcaggatg
    50581 tagcctatga caatgctaaa aaaggctact aataaacgaa cttttcttgt attatcatct
    50641 gtcactttta aaaccttctc ccatctaaca agatccttta aaaggtaaaa actcacataa
    50701 ataaagagca tatgactact tagagtgaat aataattgaa ccatttgact attataccat
    50761 cttctctgtt tgtgcgctag tttggaaact tcactcaaaa attagggatt gtttttcaag
    50821 taatcaatcg catcttgtag ggttttaacg ggcacgattt tcatatccgt cttgattgtt
    50881 ttagccgctt ctagggctgt ttggtagttg tttttcgcgt ccagatgcgc cttttgttct
    50941 tcttcgctaa cagggttatc aggagcaaag aaaatagcag cacctgccct agccgaagct
    51001 acaaccttct tatcaatacc tccaatgtct cccacattac catcgcggtc aatggtacct
    51061 gtaccggcaa caatacgacc attacgaaga tctgggtgag ctatttgagt atagatagct
    51121 agactaaaca tgagaccagc acttgggccg ccaataccag ctgttgaaaa gctaattggg
    51181 acattgctga ttacctctgt acggtcaatc aagccgattc caattccatt tttgccattt
    51241 tccaaggtga taatctttcc ttctgcagac ttggtttgcc catcctcttc ataggtgacc
    51301 ttgacggaat cccctaattt ttgagaactg acgtaatcaa tcaagtcttt ggaactatca
    51361 aaggtctgat cattgactgc tgtgactgta tcagagatat tgagaatccc tttaaaggtt
    51421 gaattatccg tcacattcaa aacataaact ccaaagtact tgagttcgat atccttacca
    51481 gctgttttta gtccttgata cttggccata ttttgcgatg tttgcatgta gaattgattg
    51541 attcgcataa attcaacatc ggaagaacca cctgtagtct cctgagcact acgaatatct
    51601 gtaaaaggtg tcaaccaagc ataaatcata tgagctaaag tggcatgttg aacaccaacc
    51661 gtaacgaatt gataggcacc agcttcctta tcttctgtgt catttacttt aaggacttgg
    51721 cgaatatctt ccgaaccacc tggaacctct atataataag gcaagggcac tacaaatgcc
    51781 aagaaagtca caatcaaggc cgcaatgacg tataagggcc atctaatctt ttttttcatt
    51841 tcttatttcc tccaaaatac tctcgggaac atggcaggca atatcctgac caaacttcaa
    51901 aagctctcga acacctgatg aactgatata gagatgttca ggccggctat gtaaataaat
    51961 agtctctata tcagaagaca gctgatgatt gtagtaatca aaactagctt catattgcaa
    52021 atccgccgca ttcctcaacc cccgtactag gaaagtagcc cccagtcttt ttgcaacatc
    52081 gaccaccaat tcatcatgag aagccacgac ttcaacattt tccaaatgtc ccaaagcctt
    52141 ttctagcccc cgtttacgat tttcaagagg gagaaatcct tgtttgtggg gattaaaaaa
    52201 aatacccaca taaagcttat caaaaagtct gctcgcccgt tcaatgatat ccagatgccc
    52261 atttgtcatc ggatcaaatg agcctgtgaa taagccaatc ttatctgaca tagactgtca
    52321 ccttactaat tccataaatc ttttccttcc agatacccag acaggcaatc tcttctggaa
    52381 gttcaacggc cttatccgtc tcgcacacaa ccataacatc ttcagaaaaa agctctctct
    52441 tagccatttt ttcaatatct gctacgattt gttccttggc atagggaggg tctaagaaaa
    52501 cgaggtcaaa ttccccagat acctgttcca atgccctctc tgcatccatc ttgaggagtt
    52561 gaaattttcc aacttccttg gtcatctgga tattttcagc cacgatggtc tgagccttac
    52621 ggtctcgctc caccaaaaca gcactggaca tgccacgcga tactgcttcg atagataaac
    52681 caccactacc tgcataaagg tccaagactc gtcccccttc aaagtaggga ccaatcatgt
    52741 taaaaatggc tcccctaacc ttatccgaag taggtcttgt tgtcttgcct tctagtgtct
    52801 tgaggggacg tcccccatag attcctgata cgattttcat actgtttatt ataccaaatt
    52861 atagacaaaa agagaaagaa aaccgaacct tgcggttcga ttctctacaa aatattttcg
    52921 taagtatcgc ggacttcttg aggccaaaca cttgtttgca cttctccgat gtgtctcttg
    52981 cgaagtagga acatggccat acgagattgt ccaattcctc caccgattgt caatgggaat
    53041 aggccattca acaaagactt gtgccattcc aattccaagc ggtcttcatc acctgtaatt
    53101 tccacctgac gtctaagagt ttcttcatct acacgaattc ccatagaaga caactcaaag
    53161 gctccaccta aagactcatt ccagacaaga atatcaccat ttagaccctt gtagccattc
    53221 tcagactcgc ttgtccagtc atcatagtct ggtgcacgtc catcgtgcgg tttaccatct
    53281 ggcaactcgc caccgatacc aatcaaaaag acggctccaa attctttaca aatcgcattt
    53341 tcacgttctt tcggtgtcaa gtctgggtag cgttctacca attcttctgt atggataaag
    53401 gtgatttgct ttggcaagat agactcgatg tcatagcgag cttcaacagc tagctcagtc
    53461 aggcgaatag ccttataaat cttctcaact gtttctttta gataaacgat gttacgctta
    53521 ccatttggga taaccttctc ccagtcccac tggtcaacat aaacagagtg ggttgcatcc
    53581 aaggaatcct catctggacg aagggctttc atgtggacaa agagaccctc tccttcacca
    53641 aagccaaaac gagccaaggt gtggcgtttc catttagcaa gtgagtgcac cacttcataa
    53701 gtagcatcag ggatttggag aaccttgacc gatactggat tttccacacc agacaggttg
    53761 tcctgcattc cgtcaccgac cttactcaag ataggacctt gaacttcgac aacttctagc
    53821 ttatctttca aatactgggt aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg
    53881 ataaaacttt tcttcataga caactcctca aaaatttaat aaacgtatta tacacctatt
    53941 tccaagaaaa gaaaagagaa aatttaaaaa aatcagtgtc actcaaaaca ctgatttcat
    54001 agacctttta gtcattgcga ccaaagatac gtagaatact taggaaaaga ttgataaaat
    54061 caagatagat gctgagagcc attgacacca cccagcctgt cgctacacga ccttgtgatt
    54121 gttcataggc gaggcgaatc ttttggttat cccaagcaat caaccctgaa aaaaccaaaa
    54181 ccatggctac gctaatcata taatcaaaga agccactagc caagaaaata ttgactacca
    54241 tagcaatcag taaaccaatg agagctgcca tcattgctcg accaatccca ctcaagtctt
    54301 tcttggtaaa gataccaact gccgccatga caaagaagag aagggcgctc gatacaaagg
    54361 cagataaaac tgtacccgga gtatagaaag ccaccacaaa actaagggta aagccgttta
    54421 aaacggagta aagtaaaaat actggaagag cagctggact atttcttgaa gccatgctac
    54481 tggcaacgaa aaccaaagcc aactccgcaa aagtagcaat ggtcaaccag agacgcccct
    54541 gcatcaacaa gtaaaccaac tgagactgaa agaccgtcaa cataaggcct gataccaaag
    54601 cagatagtcc gattcccaga ccaacaaagg cataaacctt agcgtaaaat tgattgagac
    54661 ctgcacggtc atgtataata gtgtgattca tccttttctc cttttctgtg aacatctttc
    54721 cttgattata acaaaaaaag ttaaaattag cttaaatgga agattaaaat accggctgca
    54781 actgcaacat tcaaactctc ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca
    54841 ctttcagcca taaggggact aattccttga ccctcatttc ccataactag tacaaaattt
    54901 tctatagaag gcagttctct gtaatcaaca gaatctttag atagggttgt tgctagcact
    54961 gggatagcta cctttttagt ttcgtcaaga agcgctggac tagtcatccg gtaaatgggc
    55021 agatggaaat gactaccttg catggaacgt agggttttga gactgtagat gtctgccgac
    55081 ttatctgaaa caatcactcc tgtaaaacct gctgcatccg cagttcgaat gatagttcct
    55141 acattaccgg gatcttgcac atcttccaaa aacaagaact tgccctgact caaatcagct
    55201 tgtcctactt cttctttttg aaccaccgcc acaattccct gtggagtctg agaatccgcc
    55261 aaatctagca aaatatcctc tgacacccag acagtttgcg aaaaagtagc taactgatct
    55321 cgataatttt ctagggcaaa gattttctca atcgtcactc cagcttggac agcttcttca
    55381 aacaagtgcc agccttcaat caaataggca gacttgcggt attttttttg gcgtaatttc
    55441 ttggcatttt ttaccacaga attggctttt gaggttataa tagtcataga aatattataa
    55501 cacaatcaaa gggggttggt atgcaaaagg ttagaatgat tgcccaaggt agggtacagg
    55561 gagtcggctt tcgttggggt gtttacagct tggcacttga aattggtggc atcacaggtc
    55621 gagtatggaa taacgacgat ggcacagtgg aaatcttagc ccaagcagac tcatctgcta
    55681 tcatggcaaa atttatccaa gaaatccgaa aaggaccgac acctttttca aaagtaagct
    55741 acttagatgt caaactaagc aactttcctc cctactctga ctttaaaatc gcaaattagg
    55801 tctccagaac tattgtatat tttgtaaaaa aacagtagaa tagaaaggta taatttttaa
    55861 agaaggaata aaaacagtga aatctattaa acgttttgca ttctcggcta tgggagtggc
    55921 tatgttgctt gtcttgactg gctgtgtcaa tgtcgataaa accacaggtc agccaacagg
    55981 atttatttgg aatacgatcg gagcgcctat ggctgaagcc atcaagtact tcgctactga
    56041 taaaggtcta ggctttggtg tcgctatcat tatcgtaacc attatcgtac gcttgattat
    56101 cttaccactt ggtatctacc aatcatggaa ggcaacgctt cactctgaaa agatgaacgc
    56161 tctcaagcat gtccttgagc cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga
    56221 aaaactcgaa gcccaacaag ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt
    56281 tggtggtgta ggatgtttcc ctatcctcct tcaaatgcct ttcttctctg ctatctactt
    56341 tgctgcccaa catactgaag gggttgctca agcaagctac ctaggcattc ctctaggttc
    56401 tccaagtatg attttggttg cctgtgctgg tgtcctttac tatcttcaat cgctcctttc
    56461 acttcacgga gtagaagatg aaatgcaaag agaacaaatc aagaaaatga tttacatgag
    56521 cccactcatg atcgtcgtct tctccctctt ctcaccagct agtgtcacac tttactgggt
    56581 tgtcggtggt ttcatgatga ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa
    56641 acttcgcaaa aaagtccgtg aagaactagc caagaaccca ccaaaagcaa gtgctttctc
    56701 taaaccaagt ggacgaaaag acgttacccc tgaacaacca actgctatca caagcaagaa
    56761 aaaacacaaa aatcgcaacg ctggaaaaca acgttcgaga taagaagaaa aaggcttagc
    56821 tgatttgcta agtctttttg caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta
    56881 tccatgtaca cgtttcatat aatcttgata actttcggta tccatgagtt ttttagcgtt
    56941 cttgacgcga tctgctgttg gtggtttgac tccttcgagg gaatatggaa ttccaagttc
    57001 acgccacttg aactcaccca tggtgtgata aggtagaatt tcaaacttat caacattttt
    57061 gagggtcttg acgaacttac caagttcaat caagtcatca tctctgtctg tcaatcctgg
    57121 aactagcacg tggcgaatcc agacaggttt tccaatatct gatagatact gggcacaagc
    57181 caagatattt ttattagttt ggctagtgac aatcttgtgc tgttcttcgt tgatttcctt
    57241 gatatccaaa agaaccaagt cagtgacagc catgagtttg tcaaacttct caaggtaacg
    57301 tggtttatta cggaaaggaa gagcacaggt atccaaggta cagtggattc cttgttcctt
    57361 agccttggtg aagagagcaa tcaggaaatc aatctgcaag agagcttctc ctccactgac
    57421 tgtaatccca cccttatttc cccagaaacc acggtagcgc aaggcctctg tcaagacatc
    57481 atctaccgtc cgttcacgtg acttattgga ctccatagcc caagtgtctg ggttgtggca
    57541 atactggcaa cgcatgtgac agccctgcaa aaagacaata aagcgaatac caggcccatc
    57601 tactgaccca aagctttctg tcgaatgcac cattcctgtc acttgtccat aatcaattgt
    57661 ttcttcagac atatcgttac cttccttgaa aacgttttat agttttatta tatcacgact
    57721 tgaaggaaaa acaagatttt tgcctatttt ttagaaagca atctgttttt caatttcatt
    57781 ttcaatctat tatcagatta ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc
    57841 tcagggcgct ctgcacggcg gatttgacgg gctttacctt cttcggtata gaggatttcc
    57901 gcagaacgta atttggcatt atactggtag cccattgaaa atccgtgggc acctgtatca
    57961 tgaattacca gcaaatcacc gatttctgta tgaggcagtt cgcgattgac tgcaaattta
    58021 tcattgtttt cacagagtga accaaccaca tctaccgctt cagctggtcc atctggatgg
    58081 gtcacgttgc taatatgatg gtaagctccg tacatagctg gacgcatgag gttgactgct
    58141 gaggcatcca cacctagata ggtacggtag gtttccttct tatgagtcac tcttgtgact
    58201 agagcaccgt gaggtgccag cataaaacga cccaattcgg tgaaaatctt gacctgacca
    58261 agacctgctg acgtaagaac ttcttcatac accttacgaa ctccctcacc aatcaaggcg
    58321 atatcgttcg gctcctggtc tggacgataa ttaacaccaa taccgccaga aagattgata
    58381 aagtctagcg aaatgcccaa cttttccttg atttcaacag ccagttcaaa gagctgacga
    58441 gccaactctg gataatagag atgggtcacg gtattggacg ctaggaagga gtgaatccca
    58501 aaagtcttgg ctcctttttc cttcaagata gcaaaggctt caaagagctg gtccttggtc
    58561 atgccaaact tagcctcccc aggattgtcc ataatgtctg tccccagttc aaaaacgcct
    58621 ccaggattat aacgacaaga gatgatttct ggaatgcctg ctactctctc cagatgttca
    58681 atatcttcaa aggcatccaa gttaatggtc gcacccaatt cacgtgcata ggcgtattcc
    58741 ttgtctggcg tgttgttgga agagaacata atctcagaac ccagaaagtc cagtttatgg
    58801 ctcatcaaaa gctctacata actagagcag tccacaccac aaccttcttc ttgaagaatt
    58861 ttcaaaatag ctggagttgg agtagcctta actgcaaaat attccttaaa gcccttgttc
    58921 cacgaaaaag cttggttgac ggctcttgcc ttctcacgaa tccccttctc atcatacaag
    58981 tgaaagggag tcgggaactc ggcaacaatc gcttctaact cttctctatt gataaatggt
    59041 gttttcataa gcttccttct attctgtttg caaagaaagg ctgggacaat cgttccaacc
    59101 tttagttcta tctcttattt atcttcgtca aagatattgc caacctcaac atcgatggct
    59161 tggttcttga catcaatatt ggttaccttc aagagtgact tgtagtcaaa ctgcttttca
    59221 cgttcttctt gggcattgtc cgcaaagacc gctacacctg ccagttctga gtcgaactcg
    59281 cgcaagagac taatcatacc attgaccgtt ccgccacctt tcaagaagtc atccacaatc
    59341 aagacacggc tgcctgcctt aagactacgt tttgaaagga acattttctc gatacggtca
    59401 ccacttgaac ctgaaacata gttgacgcta acagttgaac cttcggtaat tttcaggtca
    59461 cggcgcacaa tgacaaaaga gacattgagg acattggcaa ctgcatttgc aagtggcaca
    59521 cccttagttg ctacggtcat aaccgcgtca attttttggt ccataaagct tttggcaata
    59581 atacgaccaa tatttttcaa gatggctggt gtgctaagca aatcagacag atagatataa
    59641 ccacctggca agatacggtc actttctgac aacttggtac gcaagtcttc aaccatttcc
    59701 ttagcatcct gactcgaaat agacggtgtg aagatgacac ctccgccagc cccagtcact
    59761 gtctggatat gaccgatttc aatttcctca aaggcgcgtt tgataatgac gatatcttct
    59821 gagatggatg atttagcaga ctcatacttt tcagcaaaag tattgagact agttagttta
    59881 taaggattat taatcaaata gttggaaatg acaaccatcc gatcacttct tcttaatttc
    59941 atttctattt cctattccat ttttattcaa aaaatcaaaa agcaaactag aaagctggtc
    60001 gctggtggtt caaaacactg ttttgagatt gtcaatagaa ctgacaaacc ctgtaatata
    60061 cctgcatata tacatacgac aaggcgatac taccctagtt tgaagagatt ttcgaagagt
    60121 attcattttt gtcttttact tattatacca tattcacata aaaaaacgaa cattcttatc
    60181 ctaaaaaatg ctcatttttc ttaaattatc aatctaaatc tggtttatag aaggaacgat
    60241 tatccatagc gaagatttta ttggtcatct ctcctttatc caccaaagcc agagctgttg
    60301 acatcatcat catgcttgca tccagattgt caatcatatg gataatctct gcctccataa
    60361 tacgtggacg gactggactt ccatattcaa gcaagccgtg gtgactgagg atgacatgac
    60421 gaagcaaaac gacttcttcc ttggtatcat cgatgccgag ttccataact gtcttggtaa
    60481 tttcgctatc aatgagagcg atatgtccaa gaagattacc tcgcactgtg tactctgtct
    60541 ggtctggccc cgtcaactcg ataaccttag ctaagtcatg cagcataatc cccgcataga
    60601 gcaggctctt attgagctga ggataaactt cgctaatagc gtctgccaaa cgtaccatgg
    60661 tcgccgtatg ataagccaac cccgtttcaa aggcatggtg gttggtcttg gcagctggat
    60721 aggagtagaa ttccttatca tacttggtgt agagatttcg gacaatccgt tgccagacag
    60781 gattttcaat tttgaaaatc atttgcgaca tgtagtcacg aatttccttg acatcaactg
    60841 gtgacttgac cttgaaatcg gctgggtcat tgggttcacc agcttgaggc aggcggagag
    60901 taatttgatt gacttgaggg gtattgttat aaacttctcg gcgtcctttc atgtggacaa
    60961 ccttacctgc ggtaaaggcc tcaatgttat gaggttgggc atcccagagc ttcccatcaa
    61021 tctcgccact atcatcttgg aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc
    61081 tcaggtcagc tgatttgatt aggtaaaagc cttcaaatag ctcatctttt ttcatgtgac
    61141 taatcttcat attcttcctc attttcttga aaatggagta gatcaagcgc aggctcacct
    61201 tctgacaact caatgtgacg gagcgtccgc tcgatagcta tggtacgacg gtttaataat
    61261 tcatcaatat tgccagaggc atgttggaga tgtttttgtg ccttgaccag aataccacca
    61321 aacttgccaa actcggtctt gacactggca agagtcttgc tgatatggtc ggcactcttt
    61381 tggatattaa gggtcttgaa accaactgat agagagttaa gaagggctga tagggtactt
    61441 ggtcctgcaa caataatctg ttcttcccgt ctcaaatcat caaagaagac cggattgcgc
    61501 acaatctctg aataaagacc ttctgtcgga acaaacaaga ttccaaagtt ggttgtccga
    61561 ggtggtgcta tgtacttgtt cctaatatcc ctagcaaagc gcttgacgct tgctaggagt
    61621 gacttacgac agcgttcaat ctcatccttg tcacctgtct cataggcttc ttccaagcgg
    61681 taataatctg ccagtggaaa cttagagtca attggcagat agacgtattc ttggtcgcct
    61741 tgtccgggta acttgatggc atactccact cgttcactag agttttcaac cgttgcgtat
    61801 tctcgttcgt actgggcagg tgtcatgatg tcttcaataa tttgccccag ttgcaattct
    61861 cccagaatcc ctcgcgtctt ggttccagag agaaccttgt taagagctcc gacatcacgg
    61921 gcaactgtct gcatttctcc aaggccacga ttgacagact ccagttgttt agaaactgtc
    61981 tcaaaggaag cctgtaagcg tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg
    62041 cgcatttgtt ccaaacgttg ctcatttgat tcctgcaagg cttggagacg ttggtctgtc
    62101 ttgtctctag tttggaggag attatctgtc atttcttgac ggacttgggt cagaccttgg
    62161 tgcaattcaa tccgcacttc ttgcaaacgg tcgctgacaa ccacttccaa atctttttgg
    62221 tctaactggc tggcttgtct ggcttggtca aagcggtaat ccaactggtc tgacaaatga
    62281 tctgcctgat cctccaagct cttacttaag tgtttctcct gcctatcctg cctttgccaa
    62341 atcagaaaga gaccagctag attggcaatt aataatagaa taagtaaact ttccatccta
    62401 cctcctgtcc ttgctatgca gtacgaccac ataaccatct gggcaagtta ccgacacttc
    62461 cctatctata tattcgttag aagcgtacac ttttttaaag aaaaaatttt cctctgtcaa
    62521 ctcatacttg gctccaagaa tagtcagctg gctatcccga actggcataa aggctagata
    62581 gtcgtagtct gaacgaggtt ctagctgact gattccttct ggacaataag taatcaagtt
    62641 ttgcccatcc tcaatttcta tttgatgcat atagggtgcc aacttaggat tgctaggcag
    62701 aaagacattg gccaacatat ggtcaatacg gccacccaag gcaccgaaaa tagtaacctg
    62761 agcctgagga ttttgcttaa agatggtcaa gagagccaat tccaaatcag tatcatcttt
    62821 ttctggccgg gcttggacaa aatactgggc acgtttttga atcacctgtc gctcttcttc
    62881 cgtcacagaa tcaaaatctc cgactgctag agcaagaggc aaatcttctt ccaagatcca
    62941 gagcgagcct cgatccacac caacaaaacc atcaaagtcc gtccgataat gaccgcggtc
    63001 tccgcctgca aaaacggcaa ccctagtcca gttgttttct gagagtttgt actcgctcat
    63061 tgacatctcc cttaaagaca taggaacctg ctacaaaaac ggtcgcacca gcttctttgg
    63121 attgagcaat agtttggtca tcaatcccac catccacttc aatctcaaag ttcaaacctt
    63181 tttcatcacg aagggcaacc agctcacgaa ccttatccat ggtttctggc agaaaggctt
    63241 gaccaccaaa tccagggtta actgtcatga ctaggacttg gtcaactaga tgaagcacat
    63301 gcttaatcgc ttcaactggt gtaccaggat tgataacaac tgatggcttg acaccgagtg
    63361 aacgaatctt ttggagggca ccatgaatat gaggcgttgc ttccacatgg atactaataa
    63421 tatccgcacc tgcacgcaca aagtcctcta aatgatgctc agggtttgac accatcaagt
    63481 ggcagtcgaa aaccatctta ctatgaggac gaagagcttc gaccacaccc gcaccaaaac
    63541 tgatttgcgg cacaaaatga ccatccataa tatcgatatg ggcatactct gccccagttg
    63601 cttctaggcg tttaatttca cgttcaaagt tggcataatc tgctgccaga attgacggag
    63661 caatcttgta ttgagacata ggtttctcct tattttggaa tttttttgct gactttttta
    63721 taggtttctc tgcgattttc aatttcgctg aggaattgca ggtagttgtc aaaacggaag
    63781 ggtgcaatgg taccttcttc aactgctggc ttgacagcac aggacggctc atgggtatgg
    63841 gtacaagtac ggaatttgca gtctcgactg acagtggcaa tctctggaaa ggcctgattg
    63901 aggtcttcag ccgttgatac ttcataatcc agtgatgaaa agcctggtgt gtctgcgatt
    63961 ttacccccat tgaggttgta aaaactaaca gctcgagtgg tatgacgccc gcgacccaga
    64021 ctgtctgaaa tttctcccgt ttcaagatta agatctggtg cgattttatt gagaagagtt
    64081 gatttcccaa cacccgtctg ccccataaag accgtaacct tgcctgttaa caaaggcagg
    64141 agttcctctt tactggtcac aaagtcatat ccgatgtcac cataggtctg ctggtaaaaa
    64201 tccagttctc ccccgtcttc caacaaatcc attttagaaa tatagacgat gggatgaata
    64261 cccttatgct ccaaaagaac caagaaacga tccagcaaat tgctgttaaa atcaggttcc
    64321 ttgacagaca tgattactac agcttggtcg atattgacaa taggcggacg gaccagactg
    64381 tttttccgtt cgtgaatctt gagaatatag ccttctgaat tttcctcggc agagaaatct
    64441 acccagtccc caacgtaagg ggtatgccct tttttacgga aattcccacg cgcgcgtgtt
    64501 tgatagactt ggccatcact ctctacatag tagaacccag ccaaggcttt aatgatttgt
    64561 ccctgcaaaa taactccttt aaaattgtta gttccattat aacaaaaaaa agctatttta
    64621 gcttagcttc tctttacaat ttcgataagt ctattctaaa agaaaaagat acactcacgc
    64681 tttagatacc aagttttata caaaaataac gaatctacct ccttatataa aaacaggcga
    64741 acagagagcc taaaactccc tgttcgcttt actttttctg tgtgtaatag aaaaaaccta
    64801 ataaagcaag acaaaaaata tgaatataaa ctccatacat catgtgggga aagacagact
    64861 ctataaaata gcctggtaga tagatgattg gaaattgata gaaatcatag gtcgttagag
    64921 atagtaaaca aagaacatac ataaatactg ctacaattag aacccatcct tgctttcgcc
    64981 atagaaaaat catcaataag aacagacaaa gtagatagat tgaccaattt cgcaacataa
    65041 attgaaaacc ataaatcata ctttcagtcg tttctccatc aatcacatca actactttat
    65101 agaaaggtaa acaatagctc actaaaaaaa gaaggggact aattattttt ttcatattct
    65161 ctaccatgga ttattttgca agtaagctga ccatctatct ccatatcgaa tcaaattaac
    65221 agtataatta gttactaccc gattttcacc tggtccaacc ttagaaaaac ctgtgctata
    65281 ctcccaacta cttcttgcac ctggatgaaa ccatttttgc tgggatgaat accaaccacc
    65341 ttgtctaact tccacacttg aagattctat ttcgatatcc ctttcatgga agtcaactcc
    65401 tccacttatt ttagtaatat ttttttgtac acctccatca taactcaccc agtgaacaac
    65461 agtatacaat tccacactat aagtactatc aaactgactt tgatgagtag taatgttttg
    65521 agtataagcg tgcactttct gtataccaaa aatatggtct aatatattcg ttggtttagc
    65581 aagcttattg taaccctctt caacaaaagt agccttctct aaatcagcgg tataaacagt
    65641 ttttccttgt actacttgat tgtttataga agtaatacgg ctatccacaa caatgggggc
    65701 caccatatct ccatcgctag tttctatttt agctgcctct ttcacctcat atacaactcg
    65761 attttcttca gactgaatca cttctacccc atttttttca ggtatagata atctagtttg
    65821 cccattagaa accgttatat ttggaccaat attcttctca tttgcataag tcgcaatagg
    65881 aaatcctgat agaaccactg cacacataag gctattgact aatttttttc tcatgaatat
    65941 atccttccca ttttcaagag gagtaaaaat agctaatata agatgaacgt ttccttatat
    66001 ttcagaatag gatatctatc tgaaagcaat tcacactcct ataggtaact gttccaaatc
    66061 ttggctacat atatttcaat agtttgctac aaaaaactcc tttctaagtc tattgaacat
    66121 gcccttattc acctactaat atatcacaaa aataaataaa tacaagactg ttttttctac
    66181 tagttttatg atagaatagt attgttaggg taaatttcat atataaatgt cgagtgaaaa
    66241 atcgatggag cagaaatcgg tagacaaaga ctcgatttcg ttggtccagc cccacaaggc
    66301 taatcaggta tttcacgagt ttaaaaatct aatgaagtgc ccaatcaact actgattcat
    66361 tgatttaata cgaactatag tggattgaac ctagaaatag tacactaagg attctaaaac
    66421 gtttctagaa attaatttga ctttcctaat ctctttgttc atatcttatt tcaatctact
    66481 atatatacca aaatgctggg acaaaagtct ttaaaatcag agaaacgcat attatcaggt
    66541 gttggaaaac cttgataata tgcgttttat catagaaaga tctacttcat tttttaccaa
    66601 aattaagttt ttgtccctgc atcttagagt ccttgccctt taagtgcatc tgctaggctg
    66661 gcaaactctt ccaagctgag agcttcccca cgcacacttg gtgacaagcc tgcttggtcc
    66721 aaagccttgg tcagcttgtc cttgacctct tcagtcttgc caaagtaacc tgtcaagtta
    66781 ttccacaagg tcttgcggcg atgggtaaaa ctagccttgg aaaccttaaa gaaaaagttc
    66841 tcgtcttcca ctgctacagc tggcactgga cggcgcacca ttttcaagat ggctgagtct
    66901 acatttggtg ctggcacaaa gactgtacgc ggcacgataa aggcaacctt ggctgtcatg
    66961 taatactgca cagcgataga caagctaccg taagccttgg tatttggttg agccgagata
    67021 cggtccgcca cttctttttg catcatgacc acaaactcac taaaaggaat gccactctcg
    67081 attaagtgca tgagaatagg cgttgtgatg tagtaaggca aattagccac taccttgatt
    67141 ggcaggtcag gatttttgaa attctggata tgttgcgcca aatcgacctt gagaatgtcc
    67201 tcgttgacta cagtcacatt gtcaaaatca cgcaaggtat ctgccaaaat cggtaccaaa
    67261 cgatggtcga tctcaaaggc cataacttct gctgcacgct cagccaaaaa ctcggtcaag
    67321 gcaccaatac ctggcccgat ttcaatgaca ttgacctggt catcaatctc agccgtatcc
    67381 acgatttttt gtaggatatt ggtatccgtc aagaaatttt gcccaaagga ctttttaaag
    67441 gtaaaaccgt gacgctccag cactgccttg gtcacgctat aatctgcaat tctcatctat
    67501 tctcttttct attatctgtt actactattg taacacattc cccttgtatt ttgggggtga
    67561 aaatcatacc aaaaaactat ctttcctcat gaagaaagat agtcttggaa atctttaaaa
    67621 gtggccttag cgcttctctc gaaacatacg tt
//
LOCUS       DAVBOM010000004        62390 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBOM010000004 DAVBOM010000000
VERSION     DAVBOM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62390
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.004"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(141..1010)
                     /locus_tag="VQ878_000211"
     CDS             complement(141..1010)
                     /locus_tag="VQ878_000211"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET3094630.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VQ878_000212"
     CDS             complement(1012..2298)
                     /locus_tag="VQ878_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET3094631.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ878_000213"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ878_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET3094632.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VQ878_000214"
     CDS             complement(3386..4420)
                     /locus_tag="VQ878_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3094633.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4449..5882)
                     /locus_tag="VQ878_000215"
     CDS             complement(4449..5882)
                     /locus_tag="VQ878_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET3094634.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VQ878_000216"
     CDS             complement(5898..6884)
                     /locus_tag="VQ878_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3094635.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VQ878_000217"
     CDS             complement(6886..7989)
                     /locus_tag="VQ878_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET3094636.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VQ878_000218"
     CDS             complement(7979..8824)
                     /locus_tag="VQ878_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3094637.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKKVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ878_000219"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ878_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET3094638.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ878_000220"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ878_000220"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3094639.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VQ878_000221"
     CDS             complement(11219..11695)
                     /locus_tag="VQ878_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET3094640.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ878_000222"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ878_000222"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET3094641.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VQ878_000223"
     CDS             complement(13063..13401)
                     /locus_tag="VQ878_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET3094642.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VQ878_000224"
     CDS             complement(13412..14515)
                     /locus_tag="VQ878_000224"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET3094643.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ878_000225"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ878_000225"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET3094644.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VQ878_000226"
     CDS             complement(15701..16768)
                     /locus_tag="VQ878_000226"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3094645.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VQ878_000227"
     CDS             complement(16787..17641)
                     /locus_tag="VQ878_000227"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET3094646.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VQ878_000228"
     CDS             complement(17631..18308)
                     /locus_tag="VQ878_000228"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET3094647.1"
                     /translation="MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VQ878_000229"
     CDS             complement(18305..19468)
                     /locus_tag="VQ878_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET3094648.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHHFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20155..21789)
                     /locus_tag="VQ878_000230"
     CDS             complement(20155..21789)
                     /locus_tag="VQ878_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094649.1"
                     /translation="MRLKVIKKLVDINILYSSQDANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21770..22519)
                     /locus_tag="VQ878_000231"
     CDS             complement(21770..22519)
                     /locus_tag="VQ878_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094650.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22698..24152
                     /locus_tag="VQ878_000232"
     CDS             22698..24152
                     /locus_tag="VQ878_000232"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET3094651.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVELGEPFTINGWTSFTFYGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ878_000233"
     CDS             complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ878_000233"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET3094652.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDVVAGKL"
     gene            complement(26881..27366)
                     /locus_tag="VQ878_000234"
     CDS             complement(26881..27366)
                     /locus_tag="VQ878_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET3094653.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27641..27880)
                     /locus_tag="VQ878_000235"
     CDS             complement(27641..27880)
                     /locus_tag="VQ878_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094654.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28141..29211)
                     /locus_tag="VQ878_000236"
     CDS             complement(28141..29211)
                     /locus_tag="VQ878_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3094655.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29208..29981)
                     /locus_tag="VQ878_000237"
     CDS             complement(29208..29981)
                     /locus_tag="VQ878_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3094656.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29978..30784)
                     /locus_tag="VQ878_000238"
     CDS             complement(29978..30784)
                     /locus_tag="VQ878_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3094657.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30765..31922)
                     /locus_tag="VQ878_000239"
     CDS             complement(30765..31922)
                     /locus_tag="VQ878_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094658.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ878_000240"
     CDS             complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ878_000240"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET3094659.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33099..33851)
                     /locus_tag="VQ878_000241"
     CDS             complement(33099..33851)
                     /locus_tag="VQ878_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET3094660.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFTKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ878_000242"
     CDS             complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ878_000242"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET3094661.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPQIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34734..36005
                     /locus_tag="VQ878_000243"
     CDS             34734..36005
                     /locus_tag="VQ878_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET3094662.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36025..36851)
                     /locus_tag="VQ878_000244"
                     /pseudo
     CDS             complement(36025..36851)
                     /locus_tag="VQ878_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(37008..37661)
                     /gene="phoU"
                     /locus_tag="VQ878_000245"
     CDS             complement(37008..37661)
                     /gene="phoU"
                     /locus_tag="VQ878_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3094663.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37673..38431)
                     /gene="pstB"
                     /locus_tag="VQ878_000246"
     CDS             complement(37673..38431)
                     /gene="pstB"
                     /locus_tag="VQ878_000246"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3094664.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38444..39247)
                     /gene="pstB"
                     /locus_tag="VQ878_000247"
     CDS             complement(38444..39247)
                     /gene="pstB"
                     /locus_tag="VQ878_000247"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3094665.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39258..40142)
                     /gene="pstA"
                     /locus_tag="VQ878_000248"
     CDS             complement(39258..40142)
                     /gene="pstA"
                     /locus_tag="VQ878_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3094666.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40132..41049)
                     /gene="pstC"
                     /locus_tag="VQ878_000249"
     CDS             complement(40132..41049)
                     /gene="pstC"
                     /locus_tag="VQ878_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3094667.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41049..41927)
                     /gene="pstS"
                     /locus_tag="VQ878_000250"
     CDS             complement(41049..41927)
                     /gene="pstS"
                     /locus_tag="VQ878_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET3094668.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42501..43805)
                     /locus_tag="VQ878_000251"
     CDS             complement(42501..43805)
                     /locus_tag="VQ878_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET3094669.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43806..44579)
                     /locus_tag="VQ878_000252"
     CDS             complement(43806..44579)
                     /locus_tag="VQ878_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET3094670.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44569..44847)
                     /locus_tag="VQ878_000253"
     CDS             complement(44569..44847)
                     /locus_tag="VQ878_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET3094671.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44847..45248)
                     /locus_tag="VQ878_000254"
     CDS             complement(44847..45248)
                     /locus_tag="VQ878_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET3094672.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQQ
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45458..46075)
                     /locus_tag="VQ878_000255"
     CDS             complement(45458..46075)
                     /locus_tag="VQ878_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET3094673.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46065..46838)
                     /locus_tag="VQ878_000256"
     CDS             complement(46065..46838)
                     /locus_tag="VQ878_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET3094674.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46849..47586)
                     /locus_tag="VQ878_000257"
     CDS             complement(46849..47586)
                     /locus_tag="VQ878_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET3094675.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47591..48721)
                     /locus_tag="VQ878_000258"
     CDS             complement(47591..48721)
                     /locus_tag="VQ878_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET3094676.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     YGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48805..49194)
                     /locus_tag="VQ878_000259"
     CDS             complement(48805..49194)
                     /locus_tag="VQ878_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3094677.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49210..49593)
                     /locus_tag="VQ878_000260"
     CDS             complement(49210..49593)
                     /locus_tag="VQ878_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET3094678.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49594..50382)
                     /locus_tag="VQ878_000261"
     CDS             complement(49594..50382)
                     /locus_tag="VQ878_000261"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET3094679.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50375..51310)
                     /locus_tag="VQ878_000262"
     CDS             complement(50375..51310)
                     /locus_tag="VQ878_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET3094680.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51440..51616)
                     /locus_tag="VQ878_000263"
     CDS             complement(51440..51616)
                     /locus_tag="VQ878_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET3094681.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51756..52463)
                     /locus_tag="VQ878_000264"
     CDS             complement(51756..52463)
                     /locus_tag="VQ878_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET3094682.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52614..53642
                     /gene="queA"
                     /locus_tag="VQ878_000265"
     CDS             52614..53642
                     /gene="queA"
                     /locus_tag="VQ878_000265"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET3094683.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKMETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54303..54692)
                     /locus_tag="VQ878_000266"
     CDS             complement(54303..54692)
                     /locus_tag="VQ878_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3094684.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54746..55437)
                     /locus_tag="VQ878_000267"
                     /pseudo
     CDS             complement(54746..55437)
                     /locus_tag="VQ878_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(56152..56703)
                     /locus_tag="VQ878_000268"
     CDS             complement(56152..56703)
                     /locus_tag="VQ878_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3094685.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57053..57877)
                     /gene="nadE"
                     /locus_tag="VQ878_000269"
     CDS             complement(57053..57877)
                     /gene="nadE"
                     /locus_tag="VQ878_000269"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET3094686.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57874..59334)
                     /locus_tag="VQ878_000270"
     CDS             complement(57874..59334)
                     /locus_tag="VQ878_000270"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET3094687.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59450..59938)
                     /locus_tag="VQ878_000271"
     CDS             complement(59450..59938)
                     /locus_tag="VQ878_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094688.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59928..60137)
                     /locus_tag="VQ878_000272"
     CDS             complement(59928..60137)
                     /locus_tag="VQ878_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3094689.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60523..61003)
                     /locus_tag="VQ878_000273"
                     /pseudo
     CDS             complement(60523..61003)
                     /locus_tag="VQ878_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(61163..61897)
                     /locus_tag="VQ878_000274"
     CDS             complement(61163..61897)
                     /locus_tag="VQ878_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094690.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            complement(62232..>62390)
                     /locus_tag="VQ878_000275"
     CDS             complement(62232..>62390)
                     /locus_tag="VQ878_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3094691.1"
                     /translation="AKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKED
                     GTSVTVRA"
BASE COUNT        18599 a        14075 c        11473 g        18243 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga ccagcacctg gtccgtagta catagactca ccaataccga tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattaatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgctatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcggctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt tccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattaa gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtaacg agccaggacg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggtataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcggtata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaagca tagcctttta aaaaacgatg aatctgagaa
     6061 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtga
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctttgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggg cagttgcaat ttgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagcttgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatta aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaagcc
     7141 ttcttgttta gacatagaca agagaacttt cgtctgagat aaatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatctcatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagcataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag tcagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg taccttcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
     8161 gattgtcttc aaaagacgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttagcaaaag cctgcaattc ctcatgagga
    11161 aaagctatct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg tagagggttt
    11401 caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgagtcg caagcagggc aataatgggc aattcatcaa tcaatcgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacag tcaaggtaga agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac cgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat attaagggca
    12721 ttttgtggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagcc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtatgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagtcc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcacttccaa acgttccttg aaatcctcaa ttctatccag aatggtctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttaacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catcgatttc cttgccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaaggtcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatga tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 cttcccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aatccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtttcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagt aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaaaagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta
    17101 aagcacacaa atccacttta aaacctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta tctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagag ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgt catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaaaccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattggtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa atgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaatgcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtccaaacc cttaaagcgg attttctcat
    19021 aagctcctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacctccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg
    19621 aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta gcctcaggtt
    19681 aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc tggaaaattt
    19801 gattttatag agaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattataatt tcacctatct gcatcattct atttcgaact ctaaatatat
    19921 gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt gaaattgaaa
    19981 aatatcccaa taaataaact ataaacaaca aaaatagaac tatgttatat ttcttattca
    20041 aaacattcct ccctatatat ttttgattac caatcttaat catttacaac tacattctaa
    20101 caaactataa aagcgtttgt cgaactgaat ttatcaagca agcgaccaac cagctcatct
    20161 tttttctatt tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc
    20221 aagcaggagg ataagagctc ctactcccaa gctgatggca aggatagggg agagagactg
    20281 aaccaagaat atactcccaa ttacaagggc catcaggatt gcactataaa taaacaataa
    20341 aactatggcg actatgccat ttgaacgatt caccaggtcc gtaatgctac tccaattggt
    20401 tgacagattt ttcacatcct taaaataatg gtgacaagaa aggatgacac tggcaaggat
    20461 ccatgccaca ataaggtaaa tcatcgaaat gatgggcaag cctagatata gagaaagacc
    20521 aagtaaagtc agaattggta aaaaggactg aacagcaaag ataatccaaa atttcacttt
    20581 cacataacga gcaaagtcaa agggtaaact cttcagaaaa tcaacatttt ccctctccaa
    20641 ggacaaggca attgaaggca ggctggtgat attgttattg acaactgcta taaagagagc
    20701 tataaaaaac aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
    20761 gattttggaa atcagaccga tcatcatgag ataaggaagg aaagcacttg taaaaagcac
    20821 tgtaaccacg ccagtcccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
    20881 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
    20941 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
    21001 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctattgaaaa
    21061 aggctccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
    21121 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
    21181 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
    21241 agtctgagcc aagaaatgta ctgccactac cgtcactaaa gtaacagaga caaataataa
    21301 ggtcaaggac agtagcatca aaggcaaacc cagccaaaga gaaggagcta gactaatata
    21361 gagggctaga aaataagcta ggattggtac aattccagtt agagctggca agaggacaga
    21421 cagtccttta gcaattataa tctctgattc tttaaaagca tagggactat aggaggccaa
    21481 atccttactc tcataaaaga cattgtaaaa tgcagttaaa gaagttgaaa aggcaatcac
    21541 tagtaaaata gcaaccatga aactaaaata aacaggcatt tcctcaaaag gaaaatgaat
    21601 ggctatagta ctaaaaaaga tgagcatcaa gagactggaa aaaatgtaag aacttaggac
    21661 tctagcggaa acatttactt tttttccagt atttttagct tgcttctttc gtgggttagc
    21721 cagattagcg tcttgagatg aatagaggat attgatatca actaattttt taatgacctt
    21781 gagacgcatc tgaaacctcc tcttttctac cagcaaggct aaggtagata ctttccaaag
    21841 actggtctgg gttgtctttt ctcaagtcct ctaccttacc acaataaatc aaatgcccct
    21901 ttttcaaaat agcaatccga tcacagactt gctcagctac ctctagcaca tgagttgaaa
    21961 acaaaactgt cttacctttt tgcgcatgct ccttcatcat ttgcttcaaa tcaaaggcgg
    22021 cctggggatc caaaccagtc aagggttcgt ccaaaaccca aatatcagga tcagacaaga
    22081 gtgccccgat gacaaagact ttctgacgca ttccgtgaga aagagtttca ataacctgat
    22141 agcgattttc agcaaaatca aaaacgttca atagcctagc tagactagcc tccaagtcag
    22201 atctactcag atcataggat gaggcgatca attcccaaaa ttcattggcc gttaagcgta
    22261 aaaataagtc aggcgagtct gctacgtagc caatctttcg tttaatagcc aagcgatttt
    22321 ccgataactc ctgaccgtct accaaaatac gaccactgct gggtgaaatg atactgacta
    22381 gggattttat agtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
    22441 cattttcaat ctgcaaattg agattactca aggcctcttt atcaccatac aacttactaa
    22501 cattttgaaa ttcaatcatg ggacaactcc tatctttatc tgtattatat atcgctatac
    22561 tatcactttg atacaaaaaa tcaatacttt attttaagta gttaaaacag tttccttcta
    22621 ttcttacgca aacgtttgcg ctaaccaata ctttatgata gaataaagaa caagattgac
    22681 aagtaagagg aaaaatcatg caaaatcaaa cgctcatgca atactttgaa tggtatctgc
    22741 cccacgacgg tcagcactgg acgcgtctgg ctgaagatgc tccacaccta gctcatctgg
    22801 ggattagcca cgtctggatg ccaccagctt ttaaggcaac caatgaaaaa gatgtcggct
    22861 atggtgtcta tgacttattt gacctaggag agtttaacca aaaagggact gtccgcacta
    22921 agtatggttt caaagaagac tatcttcaag ccattcaagc cctaaaagca cagggaattc
    22981 aacctatggc cgatgtggtt ctcaatcaca aggctgcagc cgatcacatg gaagcctttc
    23041 aggttatcga agtggatcct gtagaccgta cggttgaact tggagaaccc ttcaccatca
    23101 atggctggac tagctttacc ttctatggtc gccaagatac ctacaatgac ttccactggc
    23161 attggtacca cttcaccggt acagactacg atgcaaaacg ccgtaagtct gggatttatc
    23221 tcatccaagg ggacaacaag ggctgggcta acgaggaatt ggtcgataac gaaaacggaa
    23281 actacgacta cctcatgtat gccgacctag actttaaaca tcctgaagtc atccaaaaca
    23341 tctatgactg ggctgattgg ttcatggaaa cgactggtgt agctggtttc cgtttggatg
    23401 ccgttaagca tattgactct ttctttatgc gcaacttcat ccgcgatatg aaggaaaaat
    23461 acggtgacga tttctatgtt tttggtgaat tttggaaccc agacaaggaa gccaatctgg
    23521 actatctcga aaaaacggaa gaacactttg accttgtcga tgttcgtctc caccagaatc
    23581 tctttgaagc cagtcaagct ggcgcaaact atgaccttcg tggcattttc acagatagcc
    23641 tggttgaact caagcctgac aagtctgtga cttttgtcga caaccacgat acccaacgag
    23701 gacaagccct tgagtctacc gttgaagaat ggttcaagcc agcagcctat gccctcattt
    23761 tgttacgcca agacggcctt ccatgtgtct tttacggaga ctactatggg atttcaggcc
    23821 agtatgctca acaagatttc aaagaaatcc ttgaccgcct cctagccatc cgaaaagatt
    23881 tggcctatgg agaacaaaat gactactttg accatgctaa ctgtatcggt tgggtacgtt
    23941 caggtgctga aaatcaatcc ccaatcgcag tcttgatttc aaatgaccaa gaaaacagca
    24001 agtcaatgtt tgtcggtcaa gaatggacta atcaaacctt tgtagattta cttggtaacc
    24061 accaaggtca agttacaatt gatgaggaag gttatggaca attccctgtc tcagctagat
    24121 ccgtaagtgt ctgggcagtc aataccatct aatagctcat aataaccaag ctaggtccaa
    24181 gcggatttgg cttttttgta gtcaaaaaag acctacccaa atggatagat ctttacttga
    24241 ttacaattta cctgctacta catccaataa ttcttggatc ttagcttggt tgcttcctcc
    24301 tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg ctaattcttt
    24361 gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat tgactttgtc
    24421 accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc agttatctgc
    24481 aaaagtacga agggcaccgg catcggatac agacacttga ctagcaatgt aacgatgacc
    24541 gttgacttcc ttagcatctt tgaagatatc gcctgcggct gcagctgcgg ctttttcttt
    24601 caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt ctaccttgtg
    24661 aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa gagcatcctc
    24721 ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac ggcgagttcc
    24781 tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag tgttgccaac
    24841 atgagtacca ccacaaagtt caatagagta gtcaccgata gtcacgacac gaacttcctt
    24901 gccgtatttc tcaccaaaga gggccatagc tcccatttct ttagcagtgt caatatccgt
    24961 ttcaactgtc ttcacttcaa gtgcttccca aattttctcg ttaacttgct gttcaatcgc
    25021 acgaagttcc tcagcagtta ctgcttggaa gtgggtaaag tcaaagcgaa ggaattcaac
    25081 ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa gggcagcgtg
    25141 aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc tatcaattac
    25201 caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat gaagggcttg
    25261 accatttggg gctttctgaa cattggtcac agtagccaca accttacctg actcatccaa
    25321 gatttgtccg tagtcagcta cctgtccacc catttcagca taaaatgacg tttccgcaaa
    25381 gataagagag gcagttcctt ctgaaacagc ttctacttct gcattgtccg ccacgatagc
    25441 taccaattta gaagacaatt ggctagcatt gtagttgaag acactttcta cagtgatgtt
    25501 ttgaagagtt tcattttgca tacccattga gccacccttg acagctgagg cacgcgcgcg
    25561 ttcttgctgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca taccagcttc
    25621 ttcagcgatt tcttcagtca attcaactgg gaacccataa gtatcataga gtttgaagac
    25681 atctgaacca gcgataacag attgaccttt ttctttcaag tctgctacaa tgccttgggc
    25741 aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct taacgatttt
    25801 ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga tttttccaac
    25861 agttggaacc aatttgtaaa ggaaaggttc gttgataccc aatttttgac catgcataga
    25921 agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg gaagggcacc
    25981 atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga agctcatgtt
    26041 gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga taatcggcat
    26101 gaagaggtcc gtttcaaagt tggtcttagc cccttggata acagccacca aacgctccaa
    26161 accagcgccc gtatcaatgt tcttatgtgg caattccttg tattcgctac gaggaacagc
    26221 agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcaatataac ggtcgttttc
    26281 aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt ccccacggtc
    26341 aaagaagatt tctgtatctg gtccagaagg tcccgcaccg atttcccaga agttgtcctc
    26401 aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt aagaatcttt
    26461 atcgtctgga tagtaggtca tgtaaagttt ttcagcaggg aaatcaaacc attcagggct
    26521 tgtcaaaagc tcataagccc aagtgatagc ttcgtcacgg aagtaatccc cgatagagaa
    26581 gttccccagc atttcaaaca tggtatggtg acgcgcggtc ttccctacgt tttcgatgtc
    26641 gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga taatggtccc
    26701 gtcaaagtat ttcttaaggg ttgctacccc agagttgatc cacaaaagag ttgggtcatt
    26761 tacaggaacc aaacttactg atggttctac tgagtgacct ttggtcgccc agaaatcaag
    26821 ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt attcacttgt
    26881 ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga gggaaatgac
    26941 taggtctgca taagcgtctt caagaaccgt tacggtatag gtagaggtca gatggaagag
    27001 ttccttctta atttccgcaa tcaactgatc gcgatcatcc agcaatttga aattcaaatc
    27061 ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat ctcgccagaa
    27121 ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct caaaacgagg
    27181 aagcaaggtc aagatttctt tactgatctg actgacttgt tcaccagccg catcatagat
    27241 ggtaaaagtt ttgggaatct taaaaaatga tccctccacc tgataggcaa tttctcccct
    27301 gtcatccttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga caagaaatgt
    27361 tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc gaaaaaccgc
    27421 ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt gtatgattga
    27481 gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg actaagacaa
    27541 gtgaaaatca attctcaact ttcttattat aacgtttttt taagcttgcg tcaactggaa
    27601 atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc aggatatatt
    27661 ttttcttact gccatttttc tttttatccc aaattttcat attactaaac acagctacta
    27721 gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt gttaggtatt
    27781 gtcgatccaa gccatccttt aaatggaata gtatagcagt ttggttaaca atcataaagg
    27841 ttggccagaa actttttttg aaaaaagtag acattttcat tatttgttgc cgctttctgt
    27901 aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca agctgtactt
    27961 gagtacggca aggcaacgct gacgtggttt gaagagtata ggcttagtat actactaggc
    28021 aagcaaataa gcaaataaac aaataaacaa ctagaataga aaaagatagg gctctaaaaa
    28081 ctgacttcta ttccttaaaa acgaaccagc ttgactgatt cgtcttctta cgtttatctc
    28141 ctacttccga tacattttaa actgtaggaa gaggtcgcta tatttccctg tccatttatg
    28201 gtcaaatttc tcataaactt ctaggtgttt catggtttca acatcgggat agaaggcctt
    28261 atcttccttt gtttcctctg ggagcaattc cttcgctggt aggtttggtg ttgaatagcc
    28321 gacatactcc gcattttgga gagcattttc aggtttcaac ataaagttga taaaggcata
    28381 ggctgagttt tggtttttaa ctgttttggg aatgaccata ttgtcaaacc aaagattgct
    28441 ggcctctgtc ggtaccacat aacgtagatt ttcatttttt tctaacattt ggctggcttc
    28501 accagagaag gtcacgccga ttgcaacatt attctgaatc atatagccct tcatctcgtc
    28561 cgcaacgata gccttgatat ttggagtcag tttgtagagc ttatccactg tctcttccaa
    28621 ctgctgcaga tccttggagt tgaggctgta gccgagggaa ttgagtccta gtcccagcac
    28681 ctcacgcgcc ccatcaaaga gcatgataga attcttatac tccggcttcc aaaggtcatc
    28741 ccaatgctca ggcgcttcat ctaccatggt ttcgttgtag acaattccta aggttcccca
    28801 gaagtaaggg atggagaatt tattacctgg gtcaaaggac tggttgagaa actctggtcc
    28861 gatattttcg attcctttaa tttttgaata atcaagcgga accaagaggt cttcgtcctt
    28921 catcttgtta atcatgtatt cacttggaat ggcaatatcg taggtcgttc caccctgctt
    28981 tatcttagtg tacatggctt cgttggagtc aaaagtctcg tactgaactt gaattcctgt
    29041 ttcttctgta aactgagtca agagttcagg atcgatatag tctccccagt tatagataac
    29101 caatttttga ctatctcgac tattgatttt actatctaaa tgagtcgcaa ttccccacaa
    29161 gacaaggata atcgctgcaa ttcctgctaa aaatgaatag atttttttca tgcttgctcc
    29221 tccttctcac gagagataaa gtaataacct acaactagga taatactaaa gagaaagact
    29281 agagcagaca gggcattgat ttctaaggaa atccccttgc gagcacgaga gtaaatctcg
    29341 actgataggg ttgaaaagcc atttcctgtt acaaagaagg tcacggcaaa atcatccagc
    29401 gaataggtga aggccatgaa gtaacctgca atgatagacg gagtcaggta aggaagcatg
    29461 atttccttaa acatctgaaa ttgactagct cccaagtcat aggccgcatg aatcatgtcg
    29521 ccattcattt ccttgagtcg aggcaagacc atcaagacca cgataggaat ggagaaggcc
    29581 acgtgactag atagaacggt caaaaagcca agtgaaaact tgagttgggt aaagagaatc
    29641 aagaagctag caccaatcat aacgtcaggc gcaaccatga ggatattatt gagtgataga
    29701 aaggcttctt ggtatttctt acgagactgg tagatgtaaa tggcaccaaa agtcccgata
    29761 atggtcgcta tcaaggctga taggaaggcc aagaaaaatg tctgagccaa aatcagcatg
    29821 agtctcccat ctccaaacat ggtttcaaag tgagtccagc taaaacctgt aaagctattc
    29881 atatcatcac cagcattaaa ggcatagcca atcaagtaaa aaatcggcag gtagaggacc
    29941 agaaagacca gtcccagata aaggttggca aattttttca tcgttctctc ctttccttgg
    30001 tcacccacat ggtgatgaac atggtcagga tgagaatcac accgatggtt gaacccatac
    30061 catagttgtc attggttaga aaattctgct caatagccgt ccccaaggtg ataacgcggt
    30121 tcccaccaat caaacgggtc agcatgaaga gactcaaact tgggataaag accgactgaa
    30181 ccccacttcg cacaccgttc atagatagag ggaagatgac atgacggaag gtctcccact
    30241 tagttgcacc aaggtcgtaa ctagcattga tgagattatt atccatatcg tctaagacat
    30301 tgaaaatcgg caaaatcata aaggggagct cgatgtagct tgcgacaaag ataaaggaaa
    30361 aatcggtaaa aagcaactgt tgtgaaccaa ttccgataaa ttccaagaat tggttaatag
    30421 agccattttg accaaaaatc ccgataaaag cataggcttt aaggagcaaa ttgatccagg
    30481 taggaaggat aatcagcatg agccagagtt gacggtgctt gagacgggtc aaaaagaggg
    30541 ctgttggata gctgataagc aaggtcacaa aggtcacaat ccctgcataa agcactgagt
    30601 tgaaactcat tttgaggtag gtcaagtttt gtgacgcaaa gtaagattta taattttcta
    30661 aactaaactg gccttcaatg ttgaaaaagg attgtccgaa aatcaagacc aagggtgcca
    30721 atacaaagag ggcaatccaa agcatgtagg gcactacaaa gagtttagag cttgttttct
    30781 tcatctcttt cctcctcgat cgcattgatc agacctgctt cttgctcttc gatttccacg
    30841 tattcttcga tacgagcatc gaactcttct tcggtttcat tgagacgcat gatgtggatg
    30901 tcttctgatt caaagtccag accgatttcc tcacccacga tggccttacg ggttgagtgg
    30961 atcatccatt catttccaag ttcgtcatag gcgataattt cataatgaac tccacggaag
    31021 agctgggtgt cgaccttaac ttggagtttg ccttcttcag gaagggtaat gcgcaagtcc
    31081 tctggacgaa taacgacctc aacaggttca tttggcttca tcccaccatc aaccgcttca
    31141 aagcgtttgc cgttaaattc gaccaagtag tcctcaatca tggtacctgg caagatgttt
    31201 gactccccga taaaggtggc aacaaagtgg ttgattggct catcgtagat gtccacaggg
    31261 gttccagact ggacaatctc gccatcattc ataacgaaaa tccagtcact catggcaaga
    31321 gcttcttcct gatcgtgagt gacaaagaca aaggtaatgc ccaatcgttg ttgtaattca
    31381 cgcaattcgt actgcatgtc tgttctcaat ttcaagtcca gcgctgataa aggctcgtcc
    31441 aacaagacca cacggggttg gttgatgata gcacgggcga tggccacacg ctgacgttgt
    31501 cctccagaaa gtttgcggat ggaacgtttt tcataacctt ccaactgaac catcttgaga
    31561 acttccgcta cacgctgctc gatttctttc ttatcaattt tacgcaagcg aagtggaaag
    31621 gcaacatttt caaacacatt catatgtggg aacaaggcat aggattggaa gacggtatgt
    31681 acgtcgcgct tgttggttgg aatatcattg atacgaacac cgtctagcat gatatctcct
    31741 gtcgtcgcat ccagtaaacc tgcaataatg tttaggatag ttgatttccc cgaaccagat
    31801 gcacctagaa gggtgtagaa tttcccttct tccaactcaa agttgatgtc tttgagaacc
    31861 ttggtgttgc tgtcttcaaa aactttagag acgtttttga attcgataat tggttttttc
    31921 aattggcata aattccttct ttttcataga ttaaccgatc ggggctctgt caggtcccca
    31981 ctacctcttg cagggagtaa aaccacctgc atacatcttc gctaccgata ggctttcacc
    32041 ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct ttcacccaag
    32101 atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc gataaccgat
    32161 tggatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat aaatcctgca
    32221 tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc ttctgaaatt
    32281 aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga tgggtattcc
    32341 aaaggttgct tgagttcacg taggtgcgtc aagcggtcca tttcctgctt gataacctga
    32401 tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga ctcctgaata
    32461 gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat ttctccatcc
    32521 ttggtcaaga ccttacaaga ctgcaagatg tgagcaatct cgccaccata ggcacccgca
    32581 ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc aaagccagtc
    32641 aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc ttctgcttca
    32701 atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac aaatccacga
    32761 atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca agggatattt
    32821 tcttggttgg caaatttcac aaggcgcgcc aactcaaaac gatttcgtgg aaagaccaaa
    32881 taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc cttaaaacgg
    32941 atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc actcttcctt
    33001 ttacaaaatt cattccatta taccattttt agagacattt gacgaccata aaaatacctt
    33061 gtttggattt tgcataagaa aaagaggttc cccccttttt atgatttttt acaaaagatt
    33121 tccttggttc cataggcgac cagaacgagc tccagtgcta gaatcacttc aaccaagact
    33181 ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa ggcatgcaag
    33241 ccataggctg ctaggagata aatccatttc ttctggcgaa cagcttggta aacccaaact
    33301 gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa ataaatctgc
    33361 cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg cataacctgt
    33421 ggattctgag tttgaactgc cgaaagaacg atgtaaagat tgagtaaact aataaggcct
    33481 agaaaaatca actccaagcc accatgccct aggccatagg ccaaggcatc tgccttttcc
    33541 aaacttctct ttttctccaa ccatttgaag aaaacaagac gagccgtttc ctcaaaaaat
    33601 gctgccatgg ctaggccata gataatatag ataagcggat gatcttgcaa gagggcaata
    33661 ctaccgtctt tttgaggatg caaaatcaag atatgcacca gtttttccaa aatctgcgaa
    33721 gagacaaaga aagcgactgc acccaagccc aagacagcta gattaatctg gtatttcttt
    33781 ttggtaaacc aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt aataatgata
    33841 tgaatggtca ttttcttctc ctattctgcc ttttcaatat cttttttcat ctcgtcaaca
    33901 ttgaacttag caaacaagta ttgacggtct tggactggga aacgttggtc caactggtca
    33961 actgctccca cctcgataat gccttccttg atgacaaaat ccatgacatg tccaccgaag
    34021 gtcaaatcat ctgatatgaa gtgcagatgg tagcctgcca cactgacccc atggaaaatc
    34081 tgaggcgtcc agaaaccaac aatagtcccc gcaacattgt cacgactata ttccggttga
    34141 tgggttgcga tatcagcaaa cttggtatcg ggtgttgact taggaatcat acgcacatgc
    34201 atatgtgaaa attccccccg aatcttgata gagcggaaaa gattttcccc atcataataa
    34261 gactcaattc gttctttcaa ttccttgtct gtcatctcaa agcgctggcg gaaaatgacc
    34321 tctgcctgat gcggtaccac tgcagcgtaa ggaataaggg catctggtga cacttccaca
    34381 atttctggct ggtctcctga ctctttggcc tgataagcct tgccatccaa gacaatcaat
    34441 tccccatcaa tggaatccaa ggttcccaaa ccaaggtcac catgttctag caattctcct
    34501 actgtcatag taccaccata aaggccagcc atcaaggctc caagagtatt gtattgaaat
    34561 aatttcactg gttcctgcac gttcttatcc attcactttc ttgtctgtta ttctataaat
    34621 cttactccta agtataccac atttgcccct agatgtgaac gagagaaacg ctctagacat
    34681 tgccaagaag gaaaaaaaag ggtacaatgt aacaaaatca agggaggtct ggaatgaaga
    34741 aacaaagcaa gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag tctggacgat
    34801 ttccgacggg tagtcgcctg ccttctatcc gtcaactgag ccttgacttt cactgcagca
    34861 aggacaccat tcaacgagcc ctgctggaat tacggcacga acaatacctc tatgccaagc
    34921 ctcagagtgg ctactatgta ttagaacaag ggcaacatca agacctagaa atcgaggtta
    34981 ccgacgaaca tgccagtgcc tatgacgatt tccgactctg tgtcaatgaa accttgattg
    35041 gccgagaaaa ctacctcttc aactactatg acaatcaaga aggattagaa gacctaagac
    35101 aatccattca caaactcctc tttgaccaag ctctctactg caaggctaac caactagtac
    35161 tgacttctgg aacccaacaa gccttgttta tcctctctca aatatccttt cctagccaag
    35221 ccaaggaaat cttggtggaa cagccaacct accatcggat gaatcgcctc ttgattgcac
    35281 aggggctgga ctatcaaacg attgaacgag gcattgatgg gattgacttg gaggagctgg
    35341 aaggccactt caaaacagga aaaattaagt ttttctacac cattcctcga tttcactatc
    35401 ccctaggcca ttcctattct gagcaggaca aacgagctat tcttgactta gcagccaaat
    35461 atagtgttta tatcgtcgaa gacgactatc tgggggattt ggactctaaa aagggccaga
    35521 ccttccacta tctagataca gaggaacgcg tcatttatat caaatccttc tcaaccagcc
    35581 tctttccagc cttgcggata acagcactca ttcttccaaa tactatcaaa gaagccttcg
    35641 tggcctacaa aaatatccta gactacgaca gcaacctcat catgcaaaag gccctgtcac
    35701 tctatattga cagtcaattg tttgaaaaaa atcgtttggc tcgcttgacc aatcatgaat
    35761 cttaccaaaa acaaatcgag gaaaggataa ctaaaacacc ttgtcccctt cctcattatc
    35821 ccctacacga tggtttattg ctagacctga gacagtatcc taaaatcgcc agtctcaaac
    35881 acagtcaact gggcttggac ttctttgaag aggcctattt aagcacctgt ccttatcaat
    35941 ttgccaaggt gtccctagac aatctggaaa atgttttaaa ctatttaaaa gcagaattgg
    36001 aatgacatcc aactctgctt tttcttattc ttcaacttca gttaaacttg ctgctttttc
    36061 aagatagctt tggtaagttc cttcatcctt aagtttttgg atgaccttgt ctaccacttc
    36121 tttcaaatca tcactatttt ttctaagagc aacgacattg gcgtcgccgt ccttcatctt
    36181 caagctgaca gttgcgacag ctaagccagc gtttttagca gcataactaa gtgcaacagg
    36241 ctcatccata tgaacagcat ctatttttcc agcctgcaat tcattgactg cttcacccat
    36301 attagttagg gaagttaatt gagcttttgg caattgttcc ttgaccattg attctggaac
    36361 agtccctttt tgggctgcaa tattagcact ttctaggcta gttaaatcct tgtatttttc
    36421 cacatcagcc ttacgaacca agaaactaat cttgttttca tagtatggga ttgaaaaatc
    36481 aaagacttct tttctctcgt cagtagcact aattcctgca actgctaggt cagccttacc
    36541 agtttgaaga ctggtcaaaa cattgtcaaa actcatgctt aagatttcca acttaacccc
    36601 aagttcatca gcgatagcct gagccatgtc gatgtctgca ccgactacct ggttctttcc
    36661 atcaaccaat gattgaaatt caaagggtgc atagtcagga ctggttgcca caactaattt
    36721 ccccttttgc ttaatggcct caacagctga ctgagaacca ttggaacctg actggcaagc
    36781 tactaagaag aaacttgcaa gaaacttgca agaaaattac ataaaacaaa tatccatttt
    36841 tttgatttca taaataaaca acctttctgt taattttgta taattataac gatatccaag
    36901 ttacttgtca agtgtttttt aaatttttat ctcaaaaata ttttttcgtt caaaaaaagg
    36961 agccatcagt tgatttcaag ctccttttta tacagaatta aactatttta tagttcgaca
    37021 atcttacctg tttcaaagta gacaacccat tcacagatat ttttagcata atcaccgata
    37081 cgctccaagt aggaaataac ttggaaataa tcacgacccg taacaatggc ttctggattt
    37141 ttcttaatct cttcagtcgc aaggtcacgg atagtttcaa aatagtggtt aatttgctca
    37201 tccatggagg ccacccggta tgcgtcgtca acagaaccat taagataaag atcaagtgct
    37261 gcttcaacaa cgcttttaac ttcacgtccc atttttttaa tttcttcctc tacagctggg
    37321 atgcgttctt cccccttcat acggatggtt gcctgggcaa tggctacagc gtgatccccc
    37381 atacgctcca catctgatac agccttaagg acagtcaaga ctgtacgcaa atcttgagag
    37441 actggttgtt ggagtgcgat catttcaaat gatttctttt ccagtttcac ttcgtattca
    37501 tttacttctg catcatcttc tatgacctct tttgccaggt cacggtcatg cgtgacaaaa
    37561 gcacgtaccg tacgattgat ttgtgagagc acttcttgtc ccatagcgta gaactggtta
    37621 tgtaatttct ctaaatcttc ttcaaattga gatcgtaaca tctttcatct ccttatccaa
    37681 attttcctgt aatatagtct tccgtttcct tgtgttgggg atcaaggaac atctgcttgg
    37741 tatcattaaa ttcaatcaaa tctccatcta ggaaaaatcc tgtcttatca gagatacgtg
    37801 aagcttgctg catggaacgg gttaccagaa gcatggtgta cttgtctttt agaccataca
    37861 aggtttcctc aattttacca gctgaaatcg gatccaaagc cgaagttggc tcatccaaga
    37921 ggatgatttt aggactagtt gccaagacac gggccacgca gacacgctgc tgttgaccac
    37981 ctgacaatcc aatagctgaa tcatatagac gatccttgac ctcatcccag atagaggcac
    38041 cttgcaaggc tttttctacg gcttcatcca gaacctgctt atccttaatt ccattgatac
    38101 gaagcccgta gacaacattc tcatagatag tcatagggaa aggattaggt tgttggaaaa
    38161 ccattccgat ttccttacgt aattcaaccg tatctgtacg cggactgtag atgttgtgac
    38221 cattgtacac cacggatcca gttgtggtca cctctggatt gagatctccc atgcggttga
    38281 gagacttgag gagggttgac ttccctgatc cagatggacc aatcaaggct gtaatttcct
    38341 taggttggaa agatagggaa acactattca aagccttctt tttattataa taaacggaca
    38401 ggtctgatac ctgtaaaatc gcatctgtca tacggtttcc tttctaacca aagtgaccag
    38461 atacatagtc attggtggac tgtagcttgg cattttggaa aatagttgca gtcttatcat
    38521 actcaatcaa atcacccaag taaaagaagc ctgtatagtc acttgcacga gcagcctgct
    38581 gcatattatg cgttacaatg atgatggtaa agtttttctt gagctcaaac atggtctctt
    38641 ctagttgcat ggtcgcaatc ggatccaagg ctgaggctgg ctcatccatt aagaggatat
    38701 ctggcttaac agagatggca cgagcgatac agagacgttg ttgctgacca cctgataagg
    38761 tcaaggctga cttgtggaga tcgtctttaa cctgatccca gagggcagcc tgacgaaggg
    38821 aggtttctac gatttcatct aggacttgct tatccttaac tccagcacgt tcatgcgcaa
    38881 aggtgatatt acggtaaatt gacttagcaa atggattggg gcgttgaaaa accattccaa
    38941 tgtgtttacg catttcataa acgttgattt ctggacggtt gacatcaatt ccacgataga
    39001 gaatctgccc agttacttta gcaatatcaa tagtatcatt catgcgattg agactgcgta
    39061 agtaggtaga tttccccgac cccgacggac caatcaaagc tgtaatttta tttctttcaa
    39121 attgcatatc aatcccctta atggattcat ttttaccata gtaaacatgg acatccttag
    39181 tagaaagggc tactttttct tcaggaaagg taaggatatg cttctcatcc cagttatatg
    39241 ttgacatggc ttctccttta ggcagcggtt aatttcttgt gtagatagct tccgaactta
    39301 cgagctccaa agttaaaaat caggataaag atcaggagca cagcggcaga acctgctgat
    39361 acaatggttc catctggaat agtgccttca ctattgactt tccagatatg gacagccaag
    39421 gtttctgctt gacggaagat agagatgggg ctagtcacac tgaggatatt ccagttagac
    39481 cagtcaagag ctggcgccga ttgccctgct gtatagatca gagctgcagc ttcgccaaag
    39541 atacgaccag atgccaagac gacacccgtt acaatacctg gaagcgcttc tggaataaca
    39601 acatgaacca ctgtctccca gcgagaaatc ccaagagcca gaccagcctc acgttgggta
    39661 tggtgaacgt gtttcaaact atcctctaca ttacgcgtca tctgaggcaa attaaagact
    39721 gtcaaggcca aggcacctga aatgattgaa aatccatact caaactggac tacaaagatc
    39781 aagtaaccaa agagacccac caccactgat ggtaaagagg acaagatttc aatacaagtc
    39841 cgcacaaagt tggtaacagg acctttttta gcatattcag ccaagtaaat cccagctccc
    39901 atagaaagag gtacagaaat aatcaaggta atgaccaata ggaaaaagga attgtaaagc
    39961 tgaatgccaa tcccaccacc tgcttgaaaa gcagaagacc ttccagtcaa gaaagaccaa
    40021 gagatatggg gcaagccccg aaccaagata tagagaatca aggaagccaa gattgtcaca
    40081 atgatgctag caatcgtata gaggacagct gttgcaagtt tatctaattt cttagcgcgc
    40141 ataatttttc tttcctcttt ctttcgtaat caatttaatc acactgttaa aaactaaact
    40201 catcaagagc agtaccaagg ccagtgacca gagaacatta ttatttacag ttcccatgac
    40261 agtgttccca attcccatag ttaatataga agttaaagtt gcagctggtg tggtcaagga
    40321 agttgggata acagctgagt ttccgacaac catctggata gctaaagcct caccaaaggc
    40381 acgcgccatc ccaaagacca ctgcagtgaa aataccagaa cgggccgcct tcaagatcac
    40441 acgccagata gtctgccagc gagtggctcc catagcgaaa cttgcctcac gataataacg
    40501 aggaaccgca cgcaagctat ccgttgtcat aaaggttacg gtcggcaaaa tcatgacaaa
    40561 gaggacggaa atccctgaca aaatcccaaa accagtccca ccaaagacac tgcgaacaaa
    40621 gggaacgacg acttgcaagc caataaatcc gtacactact gaaggaatcc caaccaggag
    40681 ttcaatagct ggttgcaaaa tcttcgcccc ttttggtgat acttcggtca taaaaactgc
    40741 tgcaccaata gcaaagggtg ttgcgataag ggctgagaga atggtaacga taaaggaacc
    40801 caaaatcata ggaagggcac caaattcttt actagaagga ttccaagttc ctcccaaaag
    40861 aaagtcaaag atattcacac cattgacaaa gaaggtcgac aagccttttt gcgctacgaa
    40921 aaccaaaatc atggccacaa ggatgactat caaagaaaga caggcaaagg tcaaaccttt
    40981 tcctaatttc tccagacgag aattctttga tggaagcaac attttcttag ctaattcttc
    41041 ttgattcatt attgtctccc ttccaacact gtcacagttc cggcagcatc tttttcaacc
    41101 ttcatttcct taatcggaat atacttcaat cctttgacaa tcccttcttg ggtctcatcc
    41161 gagagaacaa aattgagaaa ttctgcagct aactcattgg gctgccccaa tgtatacata
    41221 tgctcataag accacaaggg ccaattattg ctacttatat tttctggact taagtcatag
    41281 ccattcaact tcatgctttt gaccgaatca tctatatagg taagagataa ataagagata
    41341 gctcctggac tttttgatac gattgatttt accgctccat ttgaatcctg ctcctgactt
    41401 tgcatggcag actgaccttc cataatgaca gtatcaaagg tagcacgaga gccagagccg
    41461 gctgcccgat tgataacaga gatgggtaag tccttaccac caacctcttt ccaattggtt
    41521 acctcaccta tgaagatttg acgaagttgc tctgtcgtta gattatcaac atcaacctcc
    41581 ttattgacaa tcagagccaa gccagctacc gcgaccttgt ggtcaacaag agcagaagca
    41641 tcaattccgt ctttttcctc agcaaataca tctgagtttc ctatatcaac tgccccagac
    41701 tgaacctggg acaagcctgt accagaacct cccccttgga cattgaccgt ttttccaaca
    41761 tggatcgtgc caaattcatc tgccgctact tcaaccaagg gttgcaaggc agttgagcca
    41821 acagccgtta tggattctcc acgatcaatc cagctagcac agcctactaa acaagccgtc
    41881 agccaaaaag cgataagaga cagagcaagc ttttttcttt ttttcactgt ttttctcctc
    41941 gaaaataatt atgaatactg tgaatttttt aagtagttct ttatgagttg acgcatgaat
    42001 tcttaccaaa tttctgcgca attgattatt tatataatat aggctatatt actctttcct
    42061 aacctccttt tttcatatgt ggataaaatc tcttgtctat cccttccccc attgtcaccc
    42121 attatagtca tttcgtgtct ctttttcccc tttttaatgc aagggaaatt actctcctta
    42181 gatgataatc taaaagctag aaaggtatct caaatctctc tactctccca gactagttta
    42241 caactaaaag gaaaagattc tattttatga gaaatctagt ttacaagcgg taagaacgct
    42301 aataactaaa cttcttgtac tctttgaaaa tctcttcaaa gcagtgtttt gagctatcta
    42361 tggctagctt cctagtttgc tctttgattt tcatcgagta gtaaaactac atgtgatggc
    42421 aatcaagata tcaagaatca tcctactaaa aaaatccata ctttcactat aacatagaat
    42481 aagatatttg actagcattt tcatttgaat ctgaggcctt ttggaaaata atttttcaaa
    42541 acatttccag taacctttgc aaagcccaag ccattgcctt taaccaaaac ttggtaccaa
    42601 ccatttggca gactttctgc cagctgaacg gtttctccag ccgcatactt gacaaactct
    42661 tcttggccaa tttcaaccga ctgttcgacc tgactcggtt tcaaggctaa accaagagcg
    42721 aaactgggct caaagcgttt cttcttaaaa gtacccagat gcagtccatt gcgagcaatc
    42781 ttgagcttcc ctaaatctgg caaaagttct ggcaagagat aaagctggtc tccaaaaatc
    42841 tgcaagatac ccggtagatt gaccttcaaa tggttttggg caaattcctg ccacaaggca
    42901 acttgttcac ggctgaggtt actcttactt gccttaaatt taggagctgg attgttaccc
    42961 ttaaactgta gatgggcaac aaactgaccc tctcccttaa actgatgagg gtacatccga
    43021 gccgtttctg gcaggtcaat accagctacc attccattga tatgctctac tggcaacaag
    43081 tcaaaatcat actcttccag caaccaattg acaatctctt cgttttcctc gggtgcccag
    43141 gtacaggtcg aataaaccag acgaccacct tcagctaaca tggtcactgc atcctccaga
    43201 atttctcttt gcaagctagc acattgactc ggataatcta agctccaata gtccatagca
    43261 tcaggttgct tacgaaacat tccttcacca gagcaagggg catcaagaac gattaagtca
    43321 aaatagcctt taaagacctt gaccaagcgg tcggcagatt cattggtcac cacgacattt
    43381 gtcgctccaa aacgctccat gttttcaacc aaaatcttag cccgtttgct tgaaatttca
    43441 ttggaaacaa gtagcccctc ccctgctaga taggctgcca gttgagttga tttgcccccc
    43501 ggtgcagcag ccaagtccaa gaccttcata ccaggactgg gttgggctac ttgagccacc
    43561 atttgagcag caggttcttg cgaataaact aaacctgtag catgctcagg cgatttccct
    43621 gaaaccttcc catagtggcc ccaaggggtt tgagtaatgg catcagaaaa ggaaagttgc
    43681 tcttctttta agggattgac ccgaaaggcc gaaaccgctt cctcctcaaa agaggcaaga
    43741 aaatctcttg cctcatctcc tagtatttct ttatattttt caacaaatcc ttctggaaat
    43801 ttcatttaag ttcttttcct ttcgtaaata taggactgaa tttcctcctg catctcaaga
    43861 ggcaccatca tgaccggctg tctggtttga aaatcaggag cttcaccaaa aagggtcaca
    43921 acccgatagc ccagactttc ccctaaaata ctagctgcgg cataatccca tggttgcaga
    43981 taggtgagat aggtcaacaa acgccctgac aaaatcttgg caaaactaat ggccgcactt
    44041 ccatagacac gaacaccaag aaccgctcgg ctcaaatcag ccagccccca ttcattggtt
    44101 tccagcatac cactattccc tgcaatgaga aaatctccaa gtggtttagt tttaaaagaa
    44161 gctaggggcc tatcatttag acaaactgga aattccccac caccgtggta acaatcccct
    44221 ttgaccacat cataaatcag accaaactgt ccctgaccat tttcaaaata agccatcata
    44281 acagcaaaat cttcctgctg ggctacaaaa ttattggtac catcaatggg atcaatgacc
    44341 caaaccttgc cctcttgaac cgaggctcgc agacaacctt cttcagcaca aatcttatcc
    44401 tcaggataac gggacaaaat ctcaccaacc aagagttcct gaacttcttt gtccagtctg
    44461 gtcaccaaat ctgttggaga ggacttggtt tcaacacgca agtcttcctg catatggtca
    44521 agaatgtact gacctgcttt cttaacaagc tctttagcaa attcaaattt actttccaag
    44581 agaaatcttt ccttcccctt tttctttggc agcctgaact gctcggtaaa gtgaatagcc
    44641 actaaccgtt tcaaattctc gtcccaaacg tttctcttcg ctcttgcttg gcacgaccgc
    44701 tttgaatccc ttataggagt ccagtaactt tttagcctct actttgcctt cataggcagc
    44761 ttcaacatca ttaaaaaaag aaagcactga agcaagttct tcagtgctcc acgacaaatc
    44821 tagtgggtaa ctatactgtt tgttcattaa ctaataccag ctctcattct tgcttctttt
    44881 agttcttgct tacgataact acgagggaga aaagcacgaa tctcatcttc attaaaaccg
    44941 atttgcatac gcttggcatc aataataatt ggacgacgca aaagactagg atactgctca
    45001 atcaaatgaa gcaattccga taccgaaata ctctctacat caatattcaa tttttgaaaa
    45061 atttttgaac gagttgaaat gatgtcatca gtaccatttt cggtcaagga aaggatttgt
    45121 tgcaattctt ttcttgttaa aggactggtc ataatattgt gttccacaaa gggaacctta
    45181 tgtttttcta accaggcctt agccttacga catgatgtac agctcggtga tagaaatagt
    45241 gtaatcatgc ttttctcttc ttatctatac tttgctactt ctattataca aaaaaataag
    45301 gcgcttgact agggattttt agaaaaaaaa gcctattttt caagaaaaat aggctgtttg
    45361 cgaacgattg acacaattgg atttggttaa ttcactctta acgatggttt taaacgatat
    45421 atatttttat atatgcaaat taaaaacatc tttcatttca tttcctacga cttttcagac
    45481 acagatagcc aaagaagctt tcatagaggg caaaaaagag gaggaaggca tgaagaaaga
    45541 aggtctctgg caaaatcata ataacaggat ccttggctgg atcaaaaagc caggtatcat
    45601 ctcccacaaa gagaatttga tggaaaagag taaagaattg gtcaaaacca atcaaaactc
    45661 ccccaagtcc aatcatcaca ggtaagacta ctagagtcag gagacttttt cgataaagag
    45721 acaaaaagtc ctttttcaca attctattga caaagacata gaaacttggc agtgtcacta
    45781 gagctactag ctgaaccaaa tgaaagagat tcttgaccac tgcgaaatgg tgcagaccag
    45841 ctgctgacga acgaaaatca ggcatctgta agacctgact aaaaggattg gtcagataat
    45901 tcatcaagat atgaaaattg tattgaatgg tttctggttt tagatagact cgattcgtta
    45961 agtttagcca ctgaatctcc ataggataga aaatccaagc cagataaatg gtcagaagga
    46021 ttgagaggga gaggagaaag agcatagagc cccaaaaggt caatttagtt ttcatcaaaa
    46081 tcccactccg caaggctaga aaccacatgt gtcggtgcga ttggcaggcc agctacttct
    46141 tctgccttag taaaacctgt cgtcaccaag agcgttggaa tgccattgtc aatcccagcc
    46201 cggatatcag tcaaataatt gtccccaacc atgattaact cttcacgttc caaacctaag
    46261 tgctcaaccg ccttgtccat aatgatggca ttgggttttc cgatataaac cggcttcact
    46321 cgtgtcgcta cttcaagcag cgtaatcagt gagccagcac ctggcaaaag accgcgttcc
    46381 gtcgggatgt tgaggtcagg attggttccg ataaaatggg cacccttttg aatagcaaga
    46441 gttgctgtgg caaatttttc atagtcgact tgccaatcca gaccaactac cacgtaggca
    46501 gggttttcct tgtcttccac ataaccagcc gccttgatgg cttccttgag tcctgcttct
    46561 ccgacgacat agacggtctt ttcaagcccc aaatcattca tatagtcgat ggttgctaaa
    46621 gtcgctgtgt agacagtcga taggggcgta tcgatattaa aattctgagc caacatctcc
    46681 ttaacactct ctggagtgcg ggttgtattg ttggttacaa agagataggg aatgtcccgc
    46741 ttttgcaatt catgaacaaa agtctctcca gcagggattc ggtctttccc cttataaatg
    46801 gttccgtcta aatcaattaa atagccttta tatttcatct atttctccct aagccttttt
    46861 tatttcttgc caagtaatga ttgcttgggc attgataacc ccatcacttg taatttcatg
    46921 cttgctttcc agtccagtcc gttcaacagc cgatgtaatc accccacctg gtcgaacttc
    46981 cttgacatac ttgaggttga ttttcttggg aatatagtgg gtcaaaaaat ccgctcccat
    47041 gacctcaaaa atccagtcca agtatttact gttattgaca tgaccattca tatccaagtc
    47101 gtaaaaacga acatggtaat ccttgctgat cggctcttcc aaggattcat acttcggtcc
    47161 acggataagt tttttatcaa aatcagactg gtaaggagcc acaatctcag gttcaacaac
    47221 atggactttt cgactgtcgc ggtccatgag aacaaaggtc gccatcatgt ggatgagctc
    47281 ctgccccgct tcattataaa tagtaaagcg acggtagcaa aaaagtcgat tgtagctcaa
    47341 ggcttccgtt tcgatggtaa tttcttccgc aaaacgaggc aaacgaacca cctcaatatc
    47401 atattctgcg ataatccaga ccagattata gtcttccaaa atggccttat cactaactcc
    47461 cagttcaatc gattgcatcc ctgaaacttg cagtgacagc aaaatcacat ctggaagttt
    47521 gatatgaccg ttcatatcag ccatatcaaa aggaattttc attttcattt gataagttaa
    47581 gcccatgatc ctactccaaa ataaatcgtt ctgctacagt atctcccaaa aagagacctc
    47641 tctttgtcat gcgaacgtgg tcaccctcaa tctgcatgag gccttgttga accaagtctc
    47701 tgacaatttc tccataaagt ccagcaaaag actgtccaaa tttttcctca aatcgcgcca
    47761 tggaaacccc ggatttcttg cggagtccca agaacatttc ttcttccatt tgctcctttt
    47821 gactcaggtg atcttctgta atacaagcat tgccttcctc aaccgcactg agataatgac
    47881 gaatgggacc ataattttta taacgtactc cattgacata accagatgcc cctgcaccaa
    47941 taccatagta ttcagcattg tcccagtaca tgagattatg acgactttca aagccgggtt
    48001 tggagaaatt agaaatctca taatgctcaa aacccgctcg ctccagctct gcaatgatgt
    48061 actcaaacat ctccgcttct agttcctcct taggcagagg caatttccca cgtcgcatcc
    48121 ggttcataaa gaccgtatgg ttttctaaaa tcaaactata caaactcatg tggggaatat
    48181 ccaatccaat ggctttagcc acattttcct ttacttgctc catggtctga ccaggcagag
    48241 cataaatcaa atcaatggag atgttgtcaa aaccagccag tttcaggcga tcgatatttt
    48301 cataaatatc cttctccaaa tgactgcgcc caatcttttt caacatctta tcatcaaagg
    48361 tctggacacc tagcgaaaca cgattgacag ccgaattttt caaaacagct atcttatccg
    48421 catccaaatc gcctggattg gcttcaatgg tcaactcttc caagacagac aaatccaagt
    48481 ttttagtcaa gccattcagt aacacctcca gttgcggagc cgacagggct gtcggtgttc
    48541 caccaccgat ataaagggtt gacaactttt caatatcata agaacgaaac tcttccagca
    48601 gatgctctaa atagctgtcg actggctgat ttttgatgaa gacctttgaa aaatcacaat
    48661 aataacaaat ctgggtacaa aatgggatgt gcacataggc tgacgttggt tttttctgca
    48721 tagtaattat tataccacaa agactagatt ccagataaaa atcaccatcc ccagatacat
    48781 agtccgttcg gagatggtga tggtttattc ttctgttata tcaatcacaa tctcttctga
    48841 gtcatcaaga gcttcggctt tttcttgcca ttgttccttg agattattta attgattttt
    48901 tgatgcttct gtcgcttgaa aagcatagga tttagcttga gcaagtatac tgtccacagt
    48961 gatttcacct gactcaacct gttcttttgt tttcagaaca aaatctgtag cctgctcctt
    49021 aacttctgtc agtttttcac agacttgctc cttggcatac tccggatctt ctctcaaatc
    49081 atctagaaaa tcttgagcct gactgcaaac ttgtttgccc ttatcacttg ttaaaaacaa
    49141 ggcaagagct gcacctgaaa cggttcctaa aaggattgag gataatttac ccataaggat
    49201 tctccttttt tattttttga aaaatttact tgcaagacga agagctgaca gacttgcacc
    49261 agtcttgagt gtttttgaac cagctgatga agctttcttg ctcaagacac gcgcatggtc
    49321 attgaggtct gaaacagata gagataaatc tgcaacagca ctgaagagtg gatcaatcgt
    49381 agccaccttg acattgatat catctgccaa gacattgacc ttagccaaca actcattggt
    49441 atgatgcaag gtcacatcca catctgaagt caaggtttta atcgtctttt ctgtttcatc
    49501 gatgacacga ccaagctttt gtacagtaat gatcagatag accaaaaaga caatcaaagc
    49561 tagggcaaca agaatatatg caacttctaa catttagttt tcctcctctg taatatagta
    49621 aggggccttc tttcgatttt gataaataac gatcattata ccgagaccga taaggacaac
    49681 tgacagccat tgggacactc gaaggccgaa gaacatgaga ctatctgttc gcataccttc
    49741 gatgaccata cgaccgaaac cataccaaat caagtaaaag gccgtgatat gacctcgtct
    49801 gagactcttc catttccgtc taaaaatcag aatcaaggca aagccaagca gattccatag
    49861 agactcataa aggaaagtcg gttgacggta gctcccctca atatacatct ggtcacggat
    49921 aaagccaggt agataatcaa gattatccac tgttgcacca taagcttctt ggttaaagaa
    49981 attaccccaa cgccccaaac tttgagcaat cataacgcta ggcgccgcaa tatctagaaa
    50041 atcccaagta ttgatgagtt tacggtcagc aaagatatag agcacaagag ccccagttat
    50101 caaaccaccg taaatggcca aaccaccatt ccaaatggca aaaatctctc ctaaattctg
    50161 actatagtaa tcaaatcgga aaataacata gtagagacga gctcctaaaa tagccaaggg
    50221 aaaggctact aagataaaat ctaaaatatc gtctggtatg atcttctttc taggtgcttc
    50281 tttcatggtc aaataaaccg caagaatcaa gcctgtcaca atacataagg cataccaacg
    50341 aatggctagg ggtcctagtt gaatagcaat tggatcaagc attttgcacc tcatttcgag
    50401 cgattagact tgtcagtcgt tcgtcgaaca aacgggtcgc atcaaagccc atttccttgg
    50461 cacgataatt catggcagct gcctcaatca caacagagat attacgacct gttttaactg
    50521 gaatacgaat acgaggaatg gctacgccag aaacttcaag ttcctctgca ttgtttccaa
    50581 gacgatcaaa ggtcttatgt gtatcgtaat tttccaaata gacagcaagc tgaacctgtg
    50641 aagaatcctt gacagcactc gcaccgtaga gactcataac atcgataata ccaaccccac
    50701 gaatttcaat caagtgtttc aaaatttcag ctggttcacc ccagagagta atctcatcct
    50761 tggcaaagat atcgacacgg tcatcggcta ccaaacggtg accacgtttg acaagctcaa
    50821 gacctgtctc gctcttacca attccactat ctccctgaat caagacgccc atcccataaa
    50881 tatccatcaa gacaccgtgc acactggtac gttctgccaa acgagaatcc agatagctag
    50941 ataactctcc agataaacga ctggtagctg cacggctggt taaaatagca atcttacatt
    51001 ctctagcagc ctttaacatc tcctctggaa ccaccaaacc acgggcaaca atgactgctg
    51061 gtgtctcagg tagaaacatt tttttcaaaa cttcataacg gctgttggaa ggcatgctga
    51121 tcagataaga ccactccttc atccccaaaa gttgaatccg ctctggtgta tagtagtcaa
    51181 aatagcctgt catttcaaga ccaggtcgcg taatatccgc tatattgatt tccttttcaa
    51241 gcaattctgg ttcaccatag acaatgtcta gtctaagctt ttcaatcact tcttttacta
    51301 aaaccgacat catttcctcc ttcaaatgag ttcttctctc tattatatca aattgtagga
    51361 ggaagtttca gatttttgca ggctttggag tatttattta aaagaaaaag gactagattt
    51421 ctctagcctt tcattccaat tagaattttt tacgtttacg agctacttct gatttacgtt
    51481 tacgttttac agaaggtttt tcatagaatt cacgtttgcg tgtttcttga agagtaccag
    51541 ctttagtaac cgcacgtttg aaacggcgaa gtgcgtcgtc aagagattca ttcttacgta
    51601 ctactgtttt agacattttt ttcactccct tcaagttcaa tatctatttc attctacacg
    51661 taaaaggaat aattgtcaag caaaaatgcg gtttaatttt gattttttct tccatttata
    51721 caagagttga aagcgttcaa tagaacattg cttttttatt tttcgagtaa gctaagcgct
    51781 tcagcatctg cgatgatggt tacatcaggg tgattttgga ggctacttgc aggtaggttc
    51841 tcagtcactg ggccagatac tgttccggca atggcttctg ctttcgactc accgtaagca
    51901 aaaagaataa tagacttggc atccaaaatg tttttaatcc ccattgaaat agcttgggtt
    51961 gggacgtctt caatcttggc aaagaagcgt gcattggctt caatagtaga ctggtcaagt
    52021 tctactagat gcgtttgact gtcaaatgga gtaccaggct cattaaagcc gatatgccca
    52081 ttgcgaccaa ttcccaagat ttggaggtca actggatggt cagccaaaat ttggttgtag
    52141 cgttcaactt cagcttcagc attgtcctta acaccacgag gcaagaaact ttctttaaat
    52201 ggtttttggt tgaacaagtt ttcttgcatg aagtaacgat aagactgtgg attgtcccca
    52261 tcaaggccca catactcatc aaggttgaca ctggttagat ttgaaaaatc aaggtcactc
    52321 tcaacaattt ccttgtaaaa ttcaagtggg ctacttcctg tcgcaagtcc tagagtttga
    52381 gctccattag ccaatttttc cttcaaaatc tcaaaagcaa cttttccacc ttgaacttgg
    52441 ttttcaactt taataacttt catcttttca tcctccattt ctgtctatat ttattatatg
    52501 gtatagacca atttttgtca agtgaaaacg atttaatttc taaaaaaaga gcgtccaaac
    52561 ttgaaacgtg ttataatgga taggattata acttagaaag aatgaacaaa tatatgaata
    52621 cagctgattt tgatttccac ttgccagagg aattgattgc ccaaacgccc cttgaaaaac
    52681 gtgatgcctc caaactcctc atcgtcaacc gtgagacagg agaaatgcaa gataaacatt
    52741 tccactctat tattgatatg ctggaacctg gtgatgccct tgtcatgaac gacacccgag
    52801 ttctccctgc ccgcctctat ggtcaaaaaa tggagacagg aggtcatgtg gaacttctcc
    52861 tccttaagaa cactagtgga gacgagtggg aagttctggc taaacctgcc aaacgcctca
    52921 aggtcggtac tcgtatcagc tttggtgatg gccgcctcag cgctgtcgtt acagaagaat
    52981 tgacccacgg gggacgcatt gtccgctttg aataccaagg aattttccta gaagtcttgg
    53041 aaagtctggg agaaatgcct ctgccacctt atatccacga aaaattagat gaccgtgaac
    53101 gttatcaaac cgtctacgcc aaggaaagcg gctctgctgc agcaccgact gctggtcttc
    53161 acttcaccaa agaactgctg gcagaaatcc aagctaaggg tgttcatcta gtctatctga
    53221 ctctccatgt cggactcgga acctttagac ctgtttctgt ggataatctg gacgaacacg
    53281 aaatgcactc agagttctat caactttctg aggaagctgc tgccaccctt cgctctgtca
    53341 aagaaaatgg tggtcgcgtc atcgctgtcg gaaccacttc tatccgcacc ttggaaacta
    53401 ttggttccaa gtttgatggg caaatccaag cagattctgg ttggaccaat atctttatca
    53461 aacctgggta tgagtggaag gtcgtggatg ccttctcaac caacttccat ctgccaaaat
    53521 caactctggt catgttggtt tctgcctttg caggccgtga attagtctta gatgcctacc
    53581 accatgccat ccaagaacac taccgcttct tcagttttgg tgacgccatg tttatttatt
    53641 gagaaagaat ttctctaatt cttctaatac caataaatcg ctaagatatt atttcaaaga
    53701 acatctacaa ttgaaactct agctagctgt agaagacgcc tagtacattg aaattaaaat
    53761 gcttccccct agcttcgaaa atattgccat agattgcgtt gactctccaa attgattcat
    53821 ctatatttta tttcagcttc ctatattttc ttcgctgttt gtaaatcaaa atgcaagaca
    53881 catgagtagc accatatttg ttactcttat ctgtcctctc aagagactat tatgagttat
    53941 ttcagaatca ttcactactt tgaccctgac tctccttagt ctcaaaatca aagacttata
    54001 ctcttcaaaa atctcttcaa accgcgtcaa cgtcaccttg gattatatat gtgactgact
    54061 tcgtcagttc tatctacaac ctcaaagcag tactttgagc aacctgcgac tagttttcta
    54121 gtttgctctt tgattttcat tgagtattaa acaaaaagtg aacaaatctg aattctaatg
    54181 tacagaagac taggcttgtt cactttttta tagtcgctat aagatgacct tatctatagc
    54241 tttttatata taattatata ttcagacata ctattatcaa ttttgtcgca gggaggaatc
    54301 tgttaacgca cccattcacc attatcattg actctatagc catctatact tgtattgacc
    54361 gctaactcac ccgatgcatt tacataatac catttaccac caacttggaa ccattgattg
    54421 actttcatag aaccgttgct gttgaggtag taccatgaac cattaacttg tacccaacct
    54481 gttgccatgg aaccatcagt attataaaaa taccacatac cattttcttg tttccagtct
    54541 gttgttggag caactgcttt agctggttct actgctacat ctgttccttg gttagatgta
    54601 acagatacag gatacgaagg aatagatgat tgctcaggaa caacaacttt ttcaggttct
    54661 ctcgtccctc tccttatacg tctttttacc atctctttag taatttgacg agaagtagtt
    54721 tcttcaattg ttccatcacg ttcatctaca gtatagattg tagtaagagt aatttaccaa
    54781 tttctcctac ttcttctact tcttgacttt tatcaagagt tgggccatcg agatattctg
    54841 tttcgattgg aatttcttgg acaagaactt ggggcttggt tcttttttta acaactcttg
    54901 tttgagagtc tttttttgac ttaaagtact ctcagttact tgtccactct ttccatctac
    54961 attataagtt atcgttgtaa ctgttttccc attctttcct agagtaatct cttgctcctg
    55021 tcctgcagaa aggtcattgt ctgcttcata tttagtagca aatggaacaa gaacttcttc
    55081 aaccttgctt ttagctggaa ctttgataac tgtatccgtg gcttcttttc tatcaacagt
    55141 aacctgttcg gtaacataac cagtctctgg attaacatcg taggtccttg tcgtagttac
    55201 atagccatcc tctccatcaa ttgtaacagg attttcacta cggtcttttg tttcatcttt
    55261 ttcataacga attcgcgtac ttgaaatttt cttggttact accttaggtt tagtcgctac
    55321 ttttacaata atatccccat tgtcagcgtc atcatactct attccctctt ctttatctct
    55381 agtatcatct ctgacatatt gaatcccatc agcagcatga acaaaacttg tattcagatt
    55441 cctcctaaaa ataaagttag cccgattacc gcagaaccaa aaatctttcc gagtttacgt
    55501 attgcatagc gcttattagt attagatttt gccattacat cctacttcta gtatagcatc
    55561 ttttctatca aacgttaaac aatatacttt atatataaaa tagacttaga atgatatatt
    55621 gattattgaa ctaacacttt aactatatcg taatcaatct catatataaa ggattgcaga
    55681 catcttatct aaatacatgc taatatattt agatacaaac attccaactt gataattttc
    55741 actcatcttt catcattcct tatacaacta tgcagtataa atagaatagt tttctcatca
    55801 gaatgagact attttaatat tagataattt gatagaaaaa acatgaataa aattggttga
    55861 atttaattcc ctaactcgat agaggattct attttaaatt taacaacagc taggattaca
    55921 ctataaaaag tacattacca cctgttcggc tggagaatct agtcgattag ctccctctta
    55981 gttacaagct tcaagcgatt ttttaactaa cactaaacca gattaaagaa ggaactagaa
    56041 catctgtctt gtactaatca atatgctatt ttaaagtttc aaataaactt ggaatgctaa
    56101 ttattatatt tacaataaat agttgacttc gatagaaaca gaaaatagaa ttcaacattc
    56161 ttccctactt ataccataat aaataagatc cgcaagatag ccttttctct ctacaccatt
    56221 aacaatggtt tgtagatagg acattccagc cttttccatg acacgacctg aagctgggtt
    56281 gagactggca taacgtgctc tgaccttttg aaaacctgct tgagtaaaac aaaagtccaa
    56341 gatagctttc aaagtctctg tcatcatacc atttccccag taagccttgc ctaacacata
    56401 gccaatttca cagcttaaat cagcctcgtc tatcttaaca atgctgatat ctcctattac
    56461 ttgctctggg ttttctttta gacaaatggc ccatttataa tagttgagat tagtatagga
    56521 agcaacccaa ttgcaaatcg agtttcgagt gatttcgaca tcaggatggg gatcccaggt
    56581 aacataggtc agattctcag cggatgaagc ccaattttga aacatggctt ctgcatcact
    56641 ctccacaaat cttcttaaaa tcaaacgttc tgtctgtaat atttgcgtac cgatagattt
    56701 catgatgcta cctcacttcc ttatttctat actcgtagta aaaaggctca actcagtaac
    56761 agctagaaaa cgagtttgtc ttctaatttc ttgacgcagt tgctgcctgg tttgaaatgc
    56821 gctctagcaa gctttttcaa acctagtcat cgttgcaggg gtaagacgat gaaatcgaac
    56881 tcttcgagtt actgaatctg cctcattttc ttatttctaa actcggggtt caagatcccc
    56941 cagaccttct ctcactttct tatttcaaga tgagaggctg aaaacctcca gtggaggttt
    57001 ttcttgcttt ttaatttcag ggcaagaagc taaaaaggtc ccccggacct ttttactccc
    57061 aaaagtcatc aaatacggtg atgggtaagt ggcgtttgtg ttggcctttg tgccaccagt
    57121 tttcaatggt cgcttgagct tctgggctga ttgttttgcc ttctaggtag tcgtcaatct
    57181 ctgcgtaggt gactccaagt gcgacttcgt cagctaggcc tggtttatct tcttctaggt
    57241 ctgccgttgg gattttttca taaagggctg gctctgcgcc aagtttctgc aagagctgtt
    57301 ttccttggcg tttattgagg cggtaaagag ggagaatatc cgcaccgccg tcaccaaact
    57361 tggtaaagaa acctgtgata ttttccgcgg cgtggtctgt tccaatgacc gctccgctat
    57421 gggaaccagc aagggcatac tgagcaatca tacggcaacg tgccttgata ttccccttgt
    57481 tgaagtctga aacaggacta cctgtcgctt caactgcagc tgtcatggca tcagctgatt
    57541 ccttgatatt cacaaccaag ctgacatctg gctggatgaa ggctagggct ttttgagcat
    57601 ctgcttcatc agcttgcact ccgtatggca ggcggacagc gataaatttg tagctatcgt
    57661 ctcccgtttc agctcgcagt tcttccatag ctaattgcgc caaacgtcct gccaaggttg
    57721 agtcttgtcc cccagaaatc cctagtacaa aggtttttag gaagggatgt tttttcagat
    57781 atctttttaa gaaatcaata gaacgacgga tttcttcctg ggcatcaatc actggtttga
    57841 cacccagctc ttggataatc gtttcttgca aactcattct tcttctcctt caccaagggc
    57901 ttccttgcgc atcttatcaa tcaagtccat cttatcttgc catacatcac gcgccaaatc
    57961 cactggatag tgctgcggat tgagcacacg cttatactca tcccacaact tgtcaaattc
    58021 cttacgggca taatcctgaa tgtcagtcaa actaggcaag ttgtaaacta atattccttc
    58081 tttgaagata tccaccaaga gaggaacggc atcaaaatta cgaaccgtct tcttgatgta
    58141 tgtataggtc ggatggaaca tcttgatttc tgtcatgtcg ctaatatcca caccatcata
    58201 agtgatatag tcgccttctg acttgccttt ttcacgactg gtaatgcgcc acacctgctt
    58261 cttacctggc gtagaaactt tttcagcatt attagacagc ttaatcgtat tgcgcatctg
    58321 accagtttca tcttcgattg caacaatctt gtaaaccgcc ccaagagccg gctggtcata
    58381 ggctgtaatc agcttggtac ccacacccca gacatcaatc ttggcctttt gcatcttgag
    58441 gttaaggatg gtattttcat ctagatcatt agaagcataa atcttagcct ctgtaaatcc
    58501 agcctcatcc agttgctgac ggactttctt agaaatgtag gcaatatccc cagagtcaat
    58561 ccgcacaccc ataaagttaa tctgatcacc cagctcacgc gccacctgaa tggcagctgg
    58621 tacaccgatg cgaagggtgt cataggtatc cacaagaaag acacaatttt tgtgggtcgc
    58681 agcgtaagcc ttgaaagctt catagtcatt gccataaacc tgtaccaagg catgggcatg
    58741 ggttcccaaa acaggaatgt caaagagctt acccgcacgc acgttgctag ttccattggc
    58801 gccaccaatc acagctgcgc gtgttcccca gatggccgca tccatttctt gagcccgacg
    58861 tgtcccaaac tccatcaagg gttcatcttc gataaccgaa cgaatacgag ctgccttcgt
    58921 cgccaccaag gtctggtagt tgacgatgtt caaaagagcc gtttcgacca actgacattg
    58981 ggctagaggt ccttccacct gcacaatcgg ttcattagca aaaaccaaat ccccttcttg
    59041 ggcagaacga acggtcaact ccaacttgaa attgcgaagg taatccaaga acgccccatg
    59101 ataaccaagc gactccaaat aggctatatc actatctgaa aaacgcaagt cttcaagata
    59161 gttcacaatt ctttccaaac ctgcaaaaac cgcatagccg ttcttaaaag gctgttggcg
    59221 gaaatacacc tcaaagaccg ccttcttatt gtgaatccct tggtcaaagt aaacctgcat
    59281 catgttgatc tggtacaagt ccgtgtgcaa tgtcaaacta tcatctggat acatactttt
    59341 cctacttcct tagctagaaa cccatgaaaa ttttcaagaa ctttcatgta ttccaataaa
    59401 ttagtactat tatatcacat tttagctgga ttgagaaaag agtaacaagc tattctccac
    59461 tctccaattc atccatatct tgttcaaatt ttttctgagc ccattcgcca tagctcttaa
    59521 gaccaagatt gccaataaag atccacggaa ggtaaatgat ataagtaatg acccaagcag
    59581 acaggtattt aaaattcaaa ggattgtgct gataaatttc tatgttgaat tgataattct
    59641 gcaacatcaa aagagccgta atagccaagg ttaggaaaaa acaacccaaa atcgtaaaat
    59701 gaaaacgact atagtaggtc actcccagat aacgggcacg attgaaaaag taaaatgtcc
    59761 ctatgatgat aacgattagc agcatattag aattaaaaag gcttggtgct aatactgaaa
    59821 tgatataaga taggagcgac aaagcgatgc agatatagaa actttcagag cccgctttat
    59881 tgaacagttg ttcttctctt tcgtctagta attgataata ataaaatcta tttttcatct
    59941 tcttcctccc aaaatagttg gtctagggtt ttccctaaac atctgcaaat ggactggcag
    60001 agcgagagac tgggattgta tttccccgct tctatcaaac caatagtctg gcgcgtcacc
    60061 ccgacagcct ctgccagttg accttgtgtt aaatcacgct ctacccgagc taattttaat
    60121 tttaaatttt tagccacctt cgtcctcctt atagttttaa tactcatcta ctcttaaaaa
    60181 atccaaaacc aacacaagct atcagctatt tattataacc ccattaattt gcactccagt
    60241 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    60301 ttttattttt atttagtatt agctttagta ggatctttta aacgagtttt tattgcttat
    60361 atttcttgtt tagtttagtt ggtttcatat cactattata taatgctttt ggaaatgagc
    60421 ctagtataag tcaaaaacgt gttgaatagt gaaagcagga gcataccaag atgactgatt
    60481 tttttattgt attttaggta tgcaaaataa tactaaatga aactaaaatg aatacttctt
    60541 gcttttcttg agagtgaaaa agtacaataa aatgattgta gtgattagca caagatactg
    60601 actaatagac atcgtatttg aagccacaaa tacaggtaaa gaataaaaaa ggaagaagtt
    60661 caattgcttt gataaacaaa tcattactag tattcatcat catcgtattt aatatattag
    60721 agataaagag tagtaaagct actaaaatac caaataccaa gccacttttc aatttgtata
    60781 aatagaaaat gtaagataat agaaaataaa acaggactaa caaaattgta ttgactacaa
    60841 tagctactat aaaatttaat cctaaatcac ctggaatacc caatttactt actatgacta
    60901 gtaacacaat gccattcaaa gcataaataa tggaaactga gatagcatat agaaaattag
    60961 acaagacgta aatcatccga ttcttctgtt tatttaattt catgattata accttccttt
    61021 attttgaacg atttaggtaa atatctttaa gcgtctcttt tttagtttca aaatcaacta
    61081 ctttaataga gttttcgtta aaaaatttaa aaagctcact attttgaata ttcccagaca
    61141 tagtaattct caatccctct tcctaaacaa tatcccaaaa ttcttgtttg gtaatgaaaa
    61201 tgtctctatc tgtagctgat gaaaaagcta tctcaaacaa gaaattatga ctatcttttc
    61261 ctactttttg aaatgtcaaa agcccgttct ccaagaaaag aactctctca caaatttctt
    61321 caatgtcttc taatttatga ctcgatatta aaattcccac attttcatgt aaagctaatt
    61381 tttttagaac cgctaaaact atttgtgatg attcaatatc taaaccatta gtcggttcat
    61441 ctaaaatcaa tatatcaggt tccgtaacga gagttagaag caaagctaat ttttgttttg
    61501 tacccaaaga ataggtcttt acttttttat taatagactg agtcaaatct aactcttgga
    61561 tcaaacatct aaatctttct tgattgtagt caacaccata taaatttgac aaatatttta
    61621 aattctctaa acctgtttta gataaaaata attttggttc ttcgattaaa tacccaacat
    61681 tatcactgct tataatatta cctgaagtcg gttgattatt ctgaacaaga attttcatca
    61741 acgtactctt accaactcca tttctccctg ctagaccaac aatttcaccc ttgttaagtg
    61801 caaaatttat atctttgaga atgattgaat gaccataatg cttacttaca ttttttattc
    61861 ctccattaat attattggtt ttctctttga ttctcattaa ttttaaaaag ttgcgcctct
    61921 ttttaacaat attatatcat atatctaact taatgcaata tataaatgtc attttgtgaa
    61981 attttattaa caaaaaactc tctacaacaa aataatagag agttttctgc ttattaattt
    62041 ttttcaaaat atctaagaca tcacttcttt gtttaatttg ataggctttg atacctgagc
    62101 tccgacttta tcacttaaaa aataaaaaag acagctaatc tcttgcgcat caagggattt
    62161 cgccattctt taatctcgtt taagtgttgt atatggagct ttgcataatt ttttaaaact
    62221 aaacaactac attaagcacg aactgtgacg ctggttccat cttccttata aagattgata
    62281 agcccctctt taagagctcg aaccatgtct ccagcttgaa caggttgtgg gactttaata
    62341 gtcaatagtt ccattggatt tggagcgcgg tcgattttat tgcctttggc
//
LOCUS       DAVBOM010000005        60620 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBOM010000005 DAVBOM010000000
VERSION     DAVBOM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60620
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.005"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            127..408
                     /locus_tag="VQ878_000276"
                     /pseudo
     CDS             127..408
                     /locus_tag="VQ878_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(533..736)
                     /locus_tag="VQ878_000277"
     CDS             complement(533..736)
                     /locus_tag="VQ878_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3094692.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(729..1811)
                     /locus_tag="VQ878_000278"
     CDS             complement(729..1811)
                     /locus_tag="VQ878_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3094693.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1937..2719)
                     /locus_tag="VQ878_000279"
     CDS             complement(1937..2719)
                     /locus_tag="VQ878_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET3094694.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2719..4062)
                     /locus_tag="VQ878_000280"
     CDS             complement(2719..4062)
                     /locus_tag="VQ878_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET3094695.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4161..5477)
                     /locus_tag="VQ878_000281"
     CDS             complement(4161..5477)
                     /locus_tag="VQ878_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET3094696.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5671..6897
                     /locus_tag="VQ878_000282"
     CDS             5671..6897
                     /locus_tag="VQ878_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET3094697.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7096..8670
                     /locus_tag="VQ878_000283"
     CDS             7096..8670
                     /locus_tag="VQ878_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3094698.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8935..9723
                     /gene="codY"
                     /locus_tag="VQ878_000284"
     CDS             8935..9723
                     /gene="codY"
                     /locus_tag="VQ878_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET3094699.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9723..10298
                     /locus_tag="VQ878_000285"
     CDS             9723..10298
                     /locus_tag="VQ878_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3094700.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGNFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10380..10465
                     /locus_tag="VQ878_000286"
     tRNA            10380..10465
                     /locus_tag="VQ878_000286"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10414..10416,aa:Leu,seq:aag)
     gene            10748..11878
                     /gene="ugpC"
                     /locus_tag="VQ878_000287"
     CDS             10748..11878
                     /gene="ugpC"
                     /locus_tag="VQ878_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET3094701.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12379..13137
                     /locus_tag="VQ878_000288"
     CDS             12379..13137
                     /locus_tag="VQ878_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3094702.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13224..13736
                     /locus_tag="VQ878_000289"
     CDS             13224..13736
                     /locus_tag="VQ878_000289"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET3094703.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13918..14862
                     /locus_tag="VQ878_000290"
     CDS             13918..14862
                     /locus_tag="VQ878_000290"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET3094704.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14871..15548
                     /locus_tag="VQ878_000291"
     CDS             14871..15548
                     /locus_tag="VQ878_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET3094705.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15646..16404
                     /locus_tag="VQ878_000292"
     CDS             15646..16404
                     /locus_tag="VQ878_000292"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET3094706.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16442..17947
                     /gene="lytC"
                     /locus_tag="VQ878_000293"
     CDS             16442..17947
                     /gene="lytC"
                     /locus_tag="VQ878_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET3094707.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18444..18962
                     /locus_tag="VQ878_000294"
     CDS             18444..18962
                     /locus_tag="VQ878_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET3094708.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEASEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19092..19598
                     /locus_tag="VQ878_000295"
     CDS             19092..19598
                     /locus_tag="VQ878_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET3094709.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEL"
     gene            19800..21032
                     /gene="clpX"
                     /locus_tag="VQ878_000296"
     CDS             19800..21032
                     /gene="clpX"
                     /locus_tag="VQ878_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET3094710.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21041..21628
                     /locus_tag="VQ878_000297"
     CDS             21041..21628
                     /locus_tag="VQ878_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET3094711.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21639..22019
                     /locus_tag="VQ878_000298"
     CDS             21639..22019
                     /locus_tag="VQ878_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET3094712.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22071..22961
                     /gene="rapZ"
                     /locus_tag="VQ878_000299"
     CDS             22071..22961
                     /gene="rapZ"
                     /locus_tag="VQ878_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET3094713.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22958..23935
                     /locus_tag="VQ878_000300"
     CDS             22958..23935
                     /locus_tag="VQ878_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET3094714.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQKYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23932..24843
                     /gene="whiA"
                     /locus_tag="VQ878_000301"
     CDS             23932..24843
                     /gene="whiA"
                     /locus_tag="VQ878_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET3094715.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24877..25845)
                     /locus_tag="VQ878_000302"
     CDS             complement(24877..25845)
                     /locus_tag="VQ878_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3094716.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25981..26838
                     /locus_tag="VQ878_000303"
     CDS             25981..26838
                     /locus_tag="VQ878_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET3094717.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26825..27604
                     /locus_tag="VQ878_000304"
     CDS             26825..27604
                     /locus_tag="VQ878_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET3094718.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27628..28980
                     /locus_tag="VQ878_000305"
     CDS             27628..28980
                     /locus_tag="VQ878_000305"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET3094719.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29054..29428
                     /locus_tag="VQ878_000306"
     CDS             29054..29428
                     /locus_tag="VQ878_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET3094720.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29430..30278
                     /locus_tag="VQ878_000307"
     CDS             29430..30278
                     /locus_tag="VQ878_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3094721.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30555..31322
                     /locus_tag="VQ878_000308"
     CDS             30555..31322
                     /locus_tag="VQ878_000308"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET3094722.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31334..32518
                     /locus_tag="VQ878_000309"
     CDS             31334..32518
                     /locus_tag="VQ878_000309"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET3094723.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32515..34386
                     /locus_tag="VQ878_000310"
     CDS             32515..34386
                     /locus_tag="VQ878_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3094724.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTILSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34529..35713)
                     /gene="mntE"
                     /locus_tag="VQ878_000311"
     CDS             complement(34529..35713)
                     /gene="mntE"
                     /locus_tag="VQ878_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET3094725.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36017..38713
                     /locus_tag="VQ878_000312"
     CDS             36017..38713
                     /locus_tag="VQ878_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET3094726.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLVEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILAIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38726..39517
                     /gene="yghU"
                     /locus_tag="VQ878_000313"
     CDS             38726..39517
                     /gene="yghU"
                     /locus_tag="VQ878_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET3094727.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39633..40043
                     /locus_tag="VQ878_000314"
     CDS             39633..40043
                     /locus_tag="VQ878_000314"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3094728.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40055..41650
                     /locus_tag="VQ878_000315"
     CDS             40055..41650
                     /locus_tag="VQ878_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094729.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            41717..41881
                     /locus_tag="VQ878_000316"
     CDS             41717..41881
                     /locus_tag="VQ878_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET3094730.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41960..42688
                     /gene="yaaA"
                     /locus_tag="VQ878_000317"
     CDS             41960..42688
                     /gene="yaaA"
                     /locus_tag="VQ878_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET3094731.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTLKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42965..43513)
                     /locus_tag="VQ878_000318"
     CDS             complement(42965..43513)
                     /locus_tag="VQ878_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3094732.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            43834..44322
                     /locus_tag="VQ878_000319"
     CDS             43834..44322
                     /locus_tag="VQ878_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET3094733.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            44319..45506
                     /locus_tag="VQ878_000320"
     CDS             44319..45506
                     /locus_tag="VQ878_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3094734.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            45499..45864
                     /locus_tag="VQ878_000321"
     CDS             45499..45864
                     /locus_tag="VQ878_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3094735.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            45880..47226
                     /gene="asnS"
                     /locus_tag="VQ878_000322"
     CDS             45880..47226
                     /gene="asnS"
                     /locus_tag="VQ878_000322"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET3094736.1"
                     /translation="MMTKRVTIIDVKDYIGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            47379..47669
                     /locus_tag="VQ878_000323"
     CDS             47379..47669
                     /locus_tag="VQ878_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET3094737.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            47681..48151
                     /gene="ssbA"
                     /locus_tag="VQ878_000324"
     CDS             47681..48151
                     /gene="ssbA"
                     /locus_tag="VQ878_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET3094738.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            48183..48422
                     /locus_tag="VQ878_000325"
     CDS             48183..48422
                     /locus_tag="VQ878_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET3094739.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            48717..50117
                     /locus_tag="VQ878_000326"
     CDS             48717..50117
                     /locus_tag="VQ878_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET3094740.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGLLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            50119..50478
                     /locus_tag="VQ878_000327"
     CDS             50119..50478
                     /locus_tag="VQ878_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET3094741.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVLDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            50532..51281
                     /locus_tag="VQ878_000328"
     CDS             50532..51281
                     /locus_tag="VQ878_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET3094742.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            51271..51570
                     /locus_tag="VQ878_000329"
     CDS             51271..51570
                     /locus_tag="VQ878_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET3094743.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            51641..52576
                     /locus_tag="VQ878_000330"
     CDS             51641..52576
                     /locus_tag="VQ878_000330"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET3094744.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            52662..53174
                     /locus_tag="VQ878_000331"
     CDS             52662..53174
                     /locus_tag="VQ878_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET3094745.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            53211..53806
                     /locus_tag="VQ878_000332"
                     /pseudo
     CDS             53211..53806
                     /locus_tag="VQ878_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            53907..54101
                     /locus_tag="VQ878_000333"
     CDS             53907..54101
                     /locus_tag="VQ878_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3094746.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(54147..55592)
                     /locus_tag="VQ878_000334"
     CDS             complement(54147..55592)
                     /locus_tag="VQ878_000334"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET3094747.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HSSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            55698..57320
                     /locus_tag="VQ878_000335"
     CDS             55698..57320
                     /locus_tag="VQ878_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3094748.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALVLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            57523..59481
                     /locus_tag="VQ878_000336"
     CDS             57523..59481
                     /locus_tag="VQ878_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3094749.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVVSKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            59653..60213
                     /locus_tag="VQ878_000337"
     CDS             59653..60213
                     /locus_tag="VQ878_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094750.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTG"
     gene            60214..60588
                     /locus_tag="VQ878_000338"
     CDS             60214..60588
                     /locus_tag="VQ878_000338"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094751.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFE"
BASE COUNT        17881 a        11273 c        13718 g        17748 t
ORIGIN      
        1 aagacagaaa ttgttcaaga attaatgact gagttttcgt tagttcttct tctaaaagcc
       61 attaaactag ctcgttcgac ctactactat cacttgaaac agctagacaa aacagataag
      121 gactaaggct ggcaatacca acacgattct tatcatcggt tcctagagag taagggaatt
      181 caagcatcta tgtcacgcaa gggaaacagc caagacaacg gtatgatgga gtccttcttt
      241 ggcattttaa aatccgaaat gttttatggc tatgagaaaa catttaaatc acttaatcaa
      301 ttggaacaag ccattataga ctatattgat tattacaaca ataagaaaat taagttaaaa
      361 ctaaaaggac ttagccctgt gcaatacaga actaaatcct tcggataaat taattgtcta
      421 actttttggg ggcagtacac aatacctgat agtatgcgtt ttattgtggg aagattttcc
      481 tcattttcta gtgaaattga actttttcta acatcttttg atagatgact tcttaatcaa
      541 ttatcatttc cattgttgtt tcttggggtt tcatcccttg tctttgataa aagcggagag
      601 caccctcgtt atcattccag acacttaggg ttagattatt gcagccaatt tctttagcat
      661 aatagcagaa aaatgacaat aaaatagccc ctagatattt tgaaaggaaa gcataggggc
      721 tatatagttt aatcaaaata aagcaaatct ttgctggtgc ttgtaaagag gtcgaagcca
      781 tccttggtaa caacaccgca gtcttcaata cgaacaccga ctttaccagg gatatagata
      841 cctggttcaa cagagaagca catgccttct tcgatgacca tgtcgtttcc ttccatgata
      901 gatgggaatt catggacatc cataccgata ccatgcccga gacggtgatt gaagtactca
      961 ccataaccag ctttttcgat gacctcacgg gcagcgcggt ccacttcatg agcagtcaca
     1021 cctggcttga taaagtcaag agcagcttgt tgggcttcaa gagtcaagtt gtaaatatct
     1081 ttcttgaatt ggtctggttt gccgacagcg actgtacgag tcatatctga cgcatagcca
     1141 ttgaccagaa cacccaggtc aaagaggaga agagcatcat tttcaacctt attagctgct
     1201 ggaatgccgt gtggattcgc agcattatca ccagtcaaga ccatggtatc aaagctcatt
     1261 tcataacctt cacgtttcat ggcaaagtcg atttgtgcga tgatatctgt ctcagtctta
     1321 tcaagagaaa tattgtcaaa accaacatga acagccttgt cagcataaag acctgcaacc
     1381 atcatttttt gcacttcatc agctgatttg atgaggcgca tgcgttggat acgaggagtg
     1441 aggttgtcaa actcagcagt ctcaaaaact gttttcaaac catggtattt ggtcaagatg
     1501 agattgtcaa actcaacagc gacacgtttg aagtcaagtt gtggaagagc atgtttgatt
     1561 ttttgccatg gattttcaga atcgacatag cccactactg ggaaggaaac ggtgctactt
     1621 gcacgttcta cttcaagagc tgggacaaag aggagaggtt cctgatccgc taggacaaag
     1681 aggaacattt ggcgttcatg gggatcactg taaaaaccag tgaggtaatt gattgtgacg
     1741 gggtcagata cgacagcgac gtctagtttt tctgattcaa gatatgttag gatttgttgt
     1801 aatttagaca tatgctacct tctttctacc cctctatttt ggcaaaaaat gagagaaaat
     1861 gcaagggaga agggtaaaag aaaagacaaa aaactccgac aagataacgg agttctttga
     1921 tatcattttc ctttgtttaa gaaaagtcag ccttgctttt gacgtcactg tactcttcag
     1981 cgatttcttg gctgaggata tcctcatagg cagggagttg gatatcctga ccatatttct
     2041 tcttgagggc agtagtaact aggcgataag ccagattggc attacgagag aggataggcc
     2101 cgtggaagta ggaaccaaag acattcttat aatgaacccc ttcaccgacc ttttcttcgt
     2161 tgtttccatt tccatagaca acctgtccca gcggtttttg gtcatcagag aggaaggtac
     2221 ggccttggtg attttcaaat ccatagtagg tttcatcgaa atcttcattg tgaatcttga
     2281 tgtcaccgat aaaacggtta ttggtctggt tgagcgtgta gtgtcccatg acccctagcc
     2341 cttcgatacg ttttcctgaa gcttcaacat aatattgacc caatagttgg aaaccaccgc
     2401 agatagccag aactacaccg tcgttttgga tgtagttgtc aatgctctct tttttagcag
     2461 gtaggtcgtc tgcaatgata ctttgttcaa agtcttgacc accaccgaaa aaggcgatgt
     2521 cgtagtgatt ttcatcaaag tcatcatgga gagaaacgat gtcaacggtc acatgggctc
     2581 ccagtttttc agccacatat ttgagcatga ggatgtttcc attgtccccg taggtattca
     2641 tgagatttcc gtagaggtgg gcaatgttga gctgataggg gtaattgcca tcttttgagg
     2701 aaagtgaagt ataaaccatt agttcatctc ctttctaaca atctgacgac tagccagcag
     2761 ttcacgaaat tccagcatgg cagtataagt tgccagaata taggcatgct tgcagtcttg
     2821 attctcaatg gtcttgagaa cttgctccag attactcgtt tcagtgattt tctcagctgg
     2881 atagccagtc actcggaggc gacgagcgat ttcagaatga cgaacaccgc cagcgttgat
     2941 ttcaggaatg tccatgtcag tgatttgctc aaagtctgca tcccagatcc agctagtgtc
     3001 aattccatct gcatagttgg cattaaggag gacagatagg ctaaatggat aaggtgctag
     3061 tttgatcatt tcgatagctt gggttgcacc gactggattt ttaatcaaga caagggtaca
     3121 tttcttgtca ccgatatgaa aggtttcttg gcgtccaaag acagcacggc tcttgtcaaa
     3181 tccctgtttg atgagttgcg aatcggcacc taggaaacgg gcgatggcca cagcagctag
     3241 ggcgttatag atattataga gcccgccgat ttggataccg tattcttggc cgtctatgac
     3301 aaagcgagag cgattgttgg tcaactcaac cagttttgtc aaacgatagt cgagatcagg
     3361 acgtttacat ccacaacctt cacagatata ggcacccaag tttgcatagg tattatgctc
     3421 atatttgagg atgccttggc agtcaggaca gagaatccct tcggtattgt agtgagccag
     3481 ttgggctggt cctttttcca agtcaaaacc aaaatactct atagggtttg gaatagttgg
     3541 cttgtagaaa agtggactgt ctccgttaag gagaacagta gcagttggaa cttttcgaat
     3601 ggcatccaat atcatgttat aggtagtata gatttcaccg aaacggtcca tctggtcacg
     3661 gaagatatta gtaatgacaa aaagactagg ctggatatag tcacagatac gagatagact
     3721 ggcttcgtca atttcgagga cggcaatatt tttcccagtt tttgaagatt tggctgttag
     3781 gaaggttgtt gcaatccctg taatcatgtt ggcaccgctt gggttggtta gaacttgacc
     3841 ataaacctct tttaaaatgc cgacagtgag ggcagttgtc agggtttttc catttgttcc
     3901 agtgacaacg acaatctcgt agttcttagc taggttttgt aaaatatctt tatcaaattg
     3961 aagggcgact ttacctggga gcgtacttcc acgtccaaga cggcttaaaa cgaagtggga
     4021 agaacgccca gcaagaaggc ccaaagtagt ttttaagttc atgtttctat tatatcacaa
     4081 aagagggaaa agacagattt ggtgtttcgt agaagtaaaa acagcccaaa gagggctgtc
     4141 agttaagatg agatttcaac ttaaatcgca aacaagtcat tcaagttctc agccaaggtt
     4201 gggtgagtga agatttgttt tgtgaagtaa gtgtaaggaa tcttgttgtc catagcaaca
     4261 gtaatgatgt tgatgatttc ttgagaacct tctgagaaga tgcttgcacc aagaatttct
     4321 tttgtttcag tattaacaac agctttgaaa gctccgcgaa ggtctccatt tacgtgacca
     4381 cgaggcatgg ctgcaacagg gatttctttc actgcgtatg gaagtttcaa atcagctgct
     4441 tggctttcag tcaaaccaac ttgtgaaagt gcaggtgtga tgaacatagt atttggcaca
     4501 ttgagacggt cctcaagtgt gtagctgcca tctccagcaa ggtagctgta aacaacacgg
     4561 aagtcatcaa gtgaaatgta agtaaattga agaccaccgt tgacatctcc aactgcaaag
     4621 acaccaggaa cgtttgtttg acagtgttta tctactttaa tagcgccacg ttcagttagt
     4681 tcaatatctg tattttcaag ttgaagtggt tctacatttg gtttgcgtcc agttgcgtag
     4741 agaagggcgt cgaaacggta agtttcgtct tcagttacga caagcacttg gtcaccgtcg
     4801 tttttaattt cagtagtatg gatattttga agcaattcaa taccgtcttc ttccaggtat
     4861 tgtttagcaa gagctgcgat ggaaggttct gcacgaggta ggaatgtatc caaggcatct
     4921 aggactgtaa ccttgcttcc tagtttattg taaaggccag caaattcaag accgatattt
     4981 ccgccaccaa ggactccaag tttttcaggc aatttatcca agctttggat acctgttgag
     5041 tcaaagacgt ttttgcttgt agcaagtcca gggattggca agacgtttga aacagcacca
     5101 gtgttgatga cgatagtttc agcagtcaat tcttgttttt catcaccagc ttggatttcg
     5161 atgactttat ttgaaaggaa gtgagcttca gcatcaaaga tattgacgcc agtaccagca
     5221 acagtcgtat agtttttacc gttgaggcga ccagtgatcg tgtttttggt agcaatgact
     5281 tcttcaaaag acaagtcttt ctcagcagca accagcaaag ttttagttgg gatacaaccg
     5341 atgttgatac aagttccacc gtacatagct ttgctacgtt caacgagggc aacttttttg
     5401 ccagctgaag ccaatttacc agctagtgtt ttaccagctt taccaaatcc gataacgatt
     5461 aaatcataag ttaacattta gaattcctcc tattcgaatt acattctagc acaagaaaaa
     5521 aacttttgca caattctgct acgaaaaaga cagaaaaaga tgaaaacgct ttccagacaa
     5581 aaaactagta attttttgac aagcttgata aactaaaatc ctatctattt ttatataata
     5641 aagaataaat gttcgaaaat aggaggtttt atgaaatcga atcgttatat tattgccttt
     5701 gctggggtca ttttacactt aatgctgggt tcgacttatg cctggagtgt ttatcgtaac
     5761 cctattattg aaaaaacggg atgggatcag gcttctgttg ccttcgcctt tagtctagca
     5821 atcttttgtt tgggcttatc ggctgcattt atggggcgtt tggtagaaaa atttggtccg
     5881 aaagtcatgg gaagtctatc tgcttttcta tacgcaggtg gaaatatctt aacaggattt
     5941 gcaatagacc gtcaggagct gtggttgttg tatctcgctt atggcatttt aggtgggctt
     6001 ggtttgggag caggctatat tacccctgtg tcgacgatta taaaatggtt tcctgataaa
     6061 cgtggtctcg caacaggttt agcgattatg gggtttggtt ttgcttcttt attgactagt
     6121 cccatagcgc aacacctcat cgcaggggta gggcttgtag aaacttttta tattttagga
     6181 gcaagttact ttattatcat gctcctagct tcacaattca ttaagcgtcc aaatgagcaa
     6241 gagcttgcaa ttttatcttc ttcagggaaa gaaaaaacag cctctttgac gcaaggaatg
     6301 gctgcaaatc aggctctaaa aagcaatcgg ttttatatgc tttggattat tttctttatc
     6361 aacatagctt gtggtttagg cttaatttca gcggcatcgc caatggcaca ggagatggct
     6421 ggcttgtcta caagtcatgc agcagtaatg gtgggtgttt tggggatttt caatggattt
     6481 ggtcgcttgc tctgggcgag tttgtctgac tatatcggtc gccctctaac ctttagtata
     6541 ttactgcttg ttaatctttt cttttctctc tcactttggc tctttacaga ttccgtttta
     6601 tttgtagtcg ctatgtctat tttgatgact tgctatggag ctggtttttc attgatccca
     6661 gcttatctca gtgatatttt tggaaccaag gaattggccg ctctgcatgg atatatttta
     6721 acagcttggg caatggctgg tttagcggga cctattttat tagcagagac ttataaaatg
     6781 gctcattcgt acacacaaac cttgttcgtt tttctcattt tatacagtat cgccttggct
     6841 ttgtcttatt atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt
     6901 tctgtagaaa tgggactatc ttttgctctg gtcttgtgtt atactagata ggttgcaaag
     6961 aaaacagtac ttttcttttg tggaaaagaa gcaacacgat tttatatcta gttatatgaa
     7021 aatacgtcat aaaaagaaaa gtataaacta agccctatag ggtggcttcg caccaccttt
     7081 agaaagaaga ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt gctggcagaa
     7141 attgaaaaag ctggttttgt agaagctagt cctatccaag aacaaactat tcctttggcc
     7201 cttgaaggca aggatgttat cggtcaagct cagactggta caggaaaaac tgcagccttt
     7261 ggcttgccta cccttgaaaa aatccgtaca gaagaagcga ctatccaagc cttagtcatc
     7321 gctccaactc gtgaactagc tgtccaaagt caagaagaac tcttccgctt tggtcgtagt
     7381 aagggagtca aagtccgttc agtatatggc ggatcaagca ttgaaaaaca aattaaggct
     7441 cttaaatctg gtgcccatat cgtggtggga actccaggtc gcctcttgga cttgattaaa
     7501 cgcaaggcct tgaaattaca aaacattgaa acccttatcc ttgacgaagc ggatgaaatg
     7561 cttaacatgg gcttccttga agacatcgaa gccattattt cccgtgtacc tgagaaccgt
     7621 caaactttgc ttttctcagc aactatgcca gatgccatca aacgtatcgg tgttcagttt
     7681 atgaaagccc ctgaacatgt caagattgcg gctaaggaat tgacaacaga attggttgac
     7741 cagtactata tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg tctcatggat
     7801 gtggcacaac cagaactcgc tattgtattt ggtcgtacca aacgccgtgt ggatgaattg
     7861 actcgtggtt tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga cctagaccaa
     7921 aacaaacgtc ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt tttggttgcg
     7981 acagacgttg cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta caactacgat
     8041 attccacaag atcctgagag ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag
     8101 tcaggtcaat ctattacttt tgttgctcca aacgaaatgg gttaccttca aatcattgaa
     8161 aacttgacta agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa
     8221 tcaaaaaaac aggtagctct caagaaaatc gaacgtgatt ttgcagatga aaccattcgt
     8281 gccaattttg agaaatttgg taaggatgct cgcaaattgg ctgctgagtt tactccagaa
     8341 gaattggcaa tgtatatctt gagtctgaca gtccaagacc cagatagcct tccagaagtg
     8401 gagattgcac gtgaaaaacc actaccgttt aaaccatcag gtaatggttt cggtggtaaa
     8461 gctaagggag gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga tcgccgtggc
     8521 aatggtcgcc gtgatgagtt caaaaaagga agtcgtggca acgatcgttt tgataaggaa
     8581 aaacgttacc gtaaggataa taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc
     8641 tttgttattc gtaacaaagg tgataaataa gaaaaagcgg ttcaaaatga atcgcttttt
     8701 tatataagga gaccgaatgt gaaaaagaca aataaaatta ttatattatc ttttataata
     8761 ttatgataca caaaaatagg caacttgtca atagaaaagg aacaatttaa ttaaaaatat
     8821 tctggttttt aattaaattg taagtcaatg caagtcaata aggaattttc agataattat
     8881 tgaaaaagag acgtttttat gttataatga tagcgattaa attcgaggtg aaaaatggca
     8941 catttattag aaaaaactag aaaaattaca tcaattttga aacgctcaga ggagcagttg
     9001 caggatgagc ttccttacaa cgctattacg cgtcagttag cggatattat tcattgcaat
     9061 gcctgcatta tcaatagtaa gggacgtctg cttggctatt ttatgcgtta taaaacaaat
     9121 acagatcgcg tagagcaatt cttccaaact aagattttcc cagatgacta cgttcaaggg
     9181 gctaatatga tttacgaaac agaagcaaac ttacctgttg agcatgatat gagtattttc
     9241 cctgttgaga gtagagatga ttttccagat ggcttgacga ctattgcacc gattcatgta
     9301 tcggggattc gccttggttc tttgattatt tggcgtaatg ataaaaaatt cgaagatgag
     9361 gacttggttc ttgttgagat tgccagtacc gttgttggga ttcagcttct taacttccaa
     9421 cgtgaagaag atgagaaaaa tattcgtcgt cgtactgctg tcaccatggc ggtcaatacc
     9481 ctttcttact ccgaactccg tgctgtttca gcaattttag gggaattaaa tggaaatgaa
     9541 gggaagttga ctgcgtcagt gattgcagat cgtatcggaa tcactcgctc tgtgattgtc
     9601 aatgctcttc gtaaacttga gtctgcgggg attattgaaa gtcgctcact tggaatgaag
     9661 ggaacctatc ttaaggtctt gatttcagat atttttgaag aagtgaagaa aagagattac
     9721 taatgacaaa ggctttaatt tcgattgatt atacagaaga ttttgttgct gatagtggga
     9781 aactaacagc aggtgctcca gctcaggcga tttcggatgc catcagcaag gtaactcgat
     9841 tagcttttga acgaggagat tatatcttct ttactattga tgctcatgaa gaaaacgatt
     9901 gtttccatcc ggaaagtaag ttatttcctc ctcataatct gattgggacg agtggacgga
     9961 atttatatgg agatttgggg aacttttatc aagagcatgg ttcagacagt cgtgtctttt
    10021 ggatggataa acgccattac tcagcttttt cagggactga cctagatatt cgtttgagag
    10081 agcgtagagt gtctaccgtt atcttaacag gtgtcttgac ggatatctgt gtcctacata
    10141 cagctataga tgcctataat ctaggatatg acatcgagat tgttaaacca gctgttgctt
    10201 ccatctggcc tgaaaatcat caatttgccc taggtcattt caaaaataca ctcggagcta
    10261 agttagtaga tgaaaatcta aatgaacttt ctgagtaacc tggttggtga aaatgaaaaa
    10321 atttgaaaaa aagtgttgac aagcatccca aaagttgata tactagtaaa gtaatcgatg
    10381 cggggatggc ggaattggca gacgcgcagg actaaggatc ctgtgaccgc tttaggtcgt
    10441 gagggttcaa gtccctctct ccgcatagga aaagagttag ctaaagctag ctcttttgta
    10501 tttctctaaa aaattagaat ccagtcaaat gtagtggaga atcagcgaaa atatgggaaa
    10561 actgatcctt gtttctgctt ttgtcataga agaataataa agattatctt cttcaaattc
    10621 tccgatattc tctaaagttt tgtgcaagtt gcacagaact tttttatttt tttggtcatc
    10681 ttgccataga aatataaagc gttttcatat ataatataat tatcaaaaga caaaaggagt
    10741 tcacctcatg gtagaattga atcttaaaaa tatttacaaa aaatatccaa acagcgaaca
    10801 ctattcagtt gaagatttca acttgaacat caaagataaa gaatttatcg ttttcgtagg
    10861 accttcagga tgtggtaaat caactacact ccgtatgatt gctggtcttg aagacattac
    10921 agaaggtact gcatctatcg atggcgtggt tgtcaacgac gtagctccaa aagaccgtga
    10981 tatcgccatg gtattccaaa actacgctct ttacccacac atgactgttt atgacaacat
    11041 ggctttcggt ttgaaattgc gtaaatacag caaagaagac attaacaaac gtgttcaaga
    11101 agcagctgaa atacttggat tgaaagaatt cttggaacgt aaaccagctg acctttcagg
    11161 tggtcaacgt caacgtgttg ccatggggcg tgcgattgtc cgtgatgcga aagtattctt
    11221 gatggacgaa cctttgtcaa acttggatgc caaacttcgt gtatcaatgc gtgctgaaat
    11281 cgctaaaatt caccgtcgta tcggagctac aactatctat gtaactcacg accaaacaga
    11341 agcgatgaca cttgcagacc gtatcgttat tatgtcagct actaagaacc ctgctggtac
    11401 aggtactatc ggacgtgtag aacaaatcgg cactcctcaa gaagtttaca aaaatccagt
    11461 taacaaattc gttgcaggat tcatcggaag cccagctatg aacttcatca acgtgaaatt
    11521 ggttggtagc gaaattgttt ctgacggttt ccgtttgaaa gtgccagaag gagcattgaa
    11581 agttcttcgt gaaaaaggct acgaaggaaa agaattgatc tttggtatcc gtccagaaga
    11641 cgtgaatgca gaacctgctt tccttgaaac attcccagac tgtgttgtaa aagcgactat
    11701 ctctgtatca gaactgcttg gttcagaatc tcacctttac tgccaagttg gtaaagacga
    11761 gtttgttgca aaagttgatg ctcgtgacta cttgcaaaca ggtgcaacag ttgagcttgg
    11821 atttgacttg aacaaagcac acttcttcga tgtagaaact gaaaaaacaa tctactaaaa
    11881 taaataaaat tcaaagcact acaagaaaag atatttcttt atcaattgta gtggagagat
    11941 atcagttaat ctagggagag aaacaaaatg cttctctcct ttttgctagg gaagtcatat
    12001 tatgcatcta tattgtgatg ctctttaata ctcttcgaaa atctcttcaa accacgtcaa
    12061 cgtcgccttg ccgtacgtat gattactgac ttcgtcagtt ttatctgcaa cctcaaagct
    12121 gtactttgag cagtttacgg ctagtttcct agtttgctct ttgatttcca ttgagtatta
    12181 tttgtgggta ccatctacaa gtgaagctat atgcgtaaac tacgtgagca attgaattcg
    12241 aactagagag gtaataataa atttatgcta tagttatggt gacttgtatg cttttgattc
    12301 tagtttatca aataatagat tagaattgtc agataatatc attttgtgtt ataatgaaga
    12361 aaaaacagag gtgttcaaat gtcagaagca ggtcataagt ttttagcaaa attggggaaa
    12421 aaacgcttac gtccaggtgg aaagcgtgcc acagattggt taattgcaga aggaggattt
    12481 tcaaaagaaa agagaatact agaggttgcg tgtaataggg gaactacagc aattgagttg
    12541 gcacagcgtt ttggttgcaa gataactgct gttgatatgg atgctcaagc tttagaagtg
    12601 gctaaaaaat ctgctggaac ggcaggtgtt gctcatttaa tcagttttga aagagcaaat
    12661 gcaatgaaac ttccttatca agatgctagt tttgatattg ttataaatga agctatgctg
    12721 actatgcaag ccgatcaagc taagaaaaaa tgtgtaatgg aatatctaag ggtattaaaa
    12781 cctggaggtc ttctcttgac acatgatgta cttcttaagg aagctaaaga gtctatcaga
    12841 caggaattat cacaagcaat tcatgtaaat gtaggtcctt taactcaaga tggttgggaa
    12901 caggtgatga tagaatcagg ttattgtgat gtgaaagcat tgactggtga aatgacatta
    12961 atgaaattat cgggtatgat ttatgacgaa ggtttgctag gaactttgaa aatttgtgta
    13021 aatgcttgta aaaaggagaa tagaaagcag tttttaacta tgtataaaat gtttgctaag
    13081 aataaacaga aattgggctt tattgcgatg gctagttata aatcgtcaaa acgttagata
    13141 attattgaag ttaacttttc cttttttctt tcttaaaaaa tatgctataa tagagagtaa
    13201 aaaactttga aagaaagaaa aagatgaatt taaaagatta cattgcaaca attgaaaatt
    13261 atccaaagga aggcattacc ttccgtgata ttagtccttt gatggctgat ggaaatgctt
    13321 atagctacgc tgttcgtgaa atcgttcagt atgctactga caagaaagtc gacatgatcg
    13381 tgggacctga agctcgtgga tttatcgtgg gttgtccagt tgcctttgag ttgggaattg
    13441 gttttgcgcc tgttcgtaag ccaggtaaat tgccacgcga agttatttct gctgactatg
    13501 aaaaagagta cggtgtcgat accttgacta tgcacgcgga tgccattaag ccaggtcaac
    13561 gtgttcttat tgtagatgac cttttggcga caggtggaac tgttaaggca actatcgaga
    13621 tgattgaaaa acttggtggt gttatggcag gttgtgcctt ccttgttgaa ttggatgaat
    13681 tgaacggccg tgaaaaaatt ggtgactacg actacaaagt tcttatgcat tattaatgaa
    13741 aacagtccct agggctgttt tctctacact aggatataaa aatagactat aactagttag
    13801 agaaaaacta taattgaaaa ctatatcttc ttacagtata ataaaaggac taagtgtttg
    13861 agatttgtct tcaaacatat gcaattattc ctgaaagagt acagttagga gagggttatg
    13921 ccgattcgaa ttgataaaaa attgccagct gttgagattt tacggacaga gaatatcttt
    13981 gtcatggatg atcaacgtgc tgcccaccaa gatatccgtc ctttgaagat tttaatttta
    14041 aatctcatgc cacagaaaat ggtcacagag acccagttgt tgcgccactt ggctaataca
    14101 cccctacaac tggatattga ttttctctat atggagagcc accgttctaa aacaactcgt
    14161 tcagagcaca tggagacctt ctataaaact tttcctgaag tcaaggatga gtattttgat
    14221 gggatgatca tcacgggtgc tccagttgag catttaccat ttgaggaagt ggactattgg
    14281 gaggaattta gacagatgct tgagtggtct aagactcatg tctattcgac ccttcatatc
    14341 tgttgggggg ctcaggctgg gctttatctg cgctatggtg tagaaaaata ccagatggac
    14401 agtaagctat caggtattta tcctcaggac accctaaaag agggtcacct tctatttaga
    14461 ggctttgatg atagctatgt atcccctcat tcacggcaca cggagatttc taaggaagag
    14521 gtcttaaaca agaccaatct cgagatttta tcagaaggac ctcaggttgg ggtttctatt
    14581 ttggccagtc gtgatttacg agaaatttat agttttggtc atttggagta tgaccgtgat
    14641 accttggcaa aagagtattt tcgagatcgt gatgcaggtt tcgacccaca tattccagaa
    14701 aattacttta aagatgatga tgttaatcag gtaccttgtc tttgttggtc ttcatctgca
    14761 gccctctttt tcagtaattg ggtaaaccat gcggtctatc aggagacgcc ttttgattgg
    14821 agaaagatag aagatgatgc atctgcatat gggtatttat aagaggaatt atgacatatt
    14881 tagacgcttt taaatcaggt atcttggttt taccgagtgc cctgctcttg cattttaagg
    14941 aactctttcc ttctagcgac gattttctgg tttggcaatt tttctatttg caaaatacga
    15001 caggcttaga agaaatgtcg ccaagccaga ttgctgaaag gattggcaag gaaatttcgg
    15061 atgtcaacca gtccatttct aatctgacgg aaaggggact gctccagtat cgtactatcg
    15121 aattaaatgg cgaaattgaa ttgctctttg atgctagttt ggccttggaa cgtttggatg
    15181 acctgtttgg agcagttcat tcaagttcag accagctgac acctcaaaac cagctcaagg
    15241 atttggtgga aaccttccag caggagttgg gacgattgtt gacgcctttt gagattgagg
    15301 atttgaccaa gacactaaag gaagatggaa ccagtgctga cttgattaag gaggctcttc
    15361 gtgaagctgt tttgaatgga aaaccaaact ggaagtacat tcaggcgatt ttgagaaact
    15421 ggcgccatga aggaatcaag agtgtggctc aaattgaggc caagagagca gaaagagaag
    15481 caagcaatcc tcagttgaca caggtatctg cagatttcat aaatgccatg gatctctgga
    15541 aggattaatc catgcaagta ggcttgaaat ccgagtaaga tttgcaagct gtgtataatt
    15601 gtgatagaat aaatagaaaa taaattgaaa aaagaggtat gtgaaatgtc acgtaaacca
    15661 tttatcgctg gtaactggaa aatgaacaaa aatccagaag aagctaaagc attcgttgaa
    15721 gcagttgcat caaaacttcc ttcatcagat ctggttgaag caggtatcgc tgctccagct
    15781 cttgatttga caactgttct tgctgttgca aaaggctcaa accttaaagt tgctgctcaa
    15841 aactgctatt ttgaaaatgc aggtgctttc actggtgaaa ctagcccaca agttttgaaa
    15901 gaaatcggta ctgactacgt tgttatcggt cactcagaac gccgtgacta cttccatgaa
    15961 actgacgaag atatcaacaa aaaagcaaaa gcaatctttg cgaacggtat gcttccaatc
    16021 atctgttgtg gtgaatcact tgaaacttac gaagctggta aagctgctga attcgtaggt
    16081 gctcaagtat ctgctgcatt ggctggattg actgctgaac aagttgctgc ctcagttatc
    16141 gcttatgagc caatctgggc tatcggtact ggtaaatcag cttcacaaga cgatgcacaa
    16201 aaaatgtgta aagttgttcg tgacgttgta gctgctgact ttggtcaaga agtcgcagac
    16261 aaagttcgtg ttcaatacgg tggttctgtt aaacctgaaa atgttgcttc atacatggct
    16321 tgcccagacg ttgacggtgc ccttgtaggt ggtgcgtcac ttgaagctga aagcttcttg
    16381 gctttgcttg actttgtaaa ataatcagta agtagcaaaa gctaggtgga acagcattca
    16441 gatgtctgtt acatttttta taggagagga aagattgaaa acaaaaattg gattagcaag
    16501 tatctgttta ctaggcttgg caactagtca tgtcgctgca aatgaaactg aagtagcaaa
    16561 aacttcgcag gatacaacga cagcttcaag tagttcagag caaaatcagt cttctaataa
    16621 aacgcaaacg agcacagaag tacagactaa tgctgctgcc cactgggatg gggattatta
    16681 tgtaaaggat gatggctcta aagctcaaag tgaatggatt tttgacaact actataaggc
    16741 ctggttttat attaattcag atggtcgtta ctcgcagaat gaatggcatg gaaattacta
    16801 cctgaaatca ggtggatata tggcccaaaa cgagtggatc tatgacagta attacaagag
    16861 ttggttttat ctcaagtcag atggggctta tgctcatcaa gaatggcaat tgattggaaa
    16921 taagtggtac tacttcaaga agtggggtta catggctaaa agccaatggc aaggaagtta
    16981 tttcttgaat ggtcaaggag ctatgatgca aaatgaatgg ctctatgatc cagcctattc
    17041 tgcttatttt tatctaaaat ccgatggaac ttatgctaac caagagtggc aaaaagtggg
    17101 cggcaaatgg tactatttca agaagtgggg ctatatggct cggaatgagt ggcaaggcaa
    17161 ctactatttg actggaagtg gtgctatggc gactgacgaa gtgattatgg atggtgctcg
    17221 ctatatcttt gcggcctctg gtgagctcaa agaaaagaaa gatttgaatg tcggctgggt
    17281 tcacagagat ggtaaacgct atttctttaa taatagagaa gaacaagtgg gaaccgaaca
    17341 tgctaagaaa gtcattgata ttagtgagca caatggtcgt atcaatgatt ggaaaaaggt
    17401 tattgatgag aacgaggtgg atggtgtcat tgttcgtcta ggttatagcg gtaaagaaga
    17461 caaggaattg gcgcataaca ttaaggagtt aaaccgtctg ggaattcctt atggtgtcta
    17521 tctctatacc tatgctgaaa atgagaccga tgctgagaat gacgctaaac agaccattga
    17581 acttataaag aaatacaata tgaacctgtc ttaccctatc tattatgatg ttgagaactg
    17641 ggaatatgta aataagagca agagagctcc aagtgataca gacacttggg ttaaaatcat
    17701 caacaagtac atggacacga tgaagcaggc gggttatcaa aatgtgtatg tctatagcta
    17761 tcgtagttta ttacagacgc gtttaaaaca cccagatatt ttaaaacatg taaactgggt
    17821 agcggcctat acgaatgctt tagaatggga aaacccttat tattcaggag aaaaaggttg
    17881 gcaatatacc tcttctgaat acatgaaagg aatccaaggg cgcgtagatg tcagcgtttg
    17941 gtattaagcg atgatttgaa agagggatgt gatagtagca ccctcttttt ctttgtttta
    18001 tgatagttca tcctcgagta aattcaagat cttgctcgga aatgaagctt atatagtaga
    18061 ttgaatatag acaaagacct tgtgattggt aaaacatttt agaaattcat ttacctttcc
    18121 taatcgactt ggtttcatct tatttcaatc tattatagta ttggggaatt tcttcaaacc
    18181 acatcagctt ggtcagttct acctgcgacc tcaaaacttg tgctttggtc aagctgggtt
    18241 tagtttccta gtttgctgat ggatttccat tgactataag catccaaccc tcttttttgt
    18301 cttctaaaga attcttaaat tatcagtcta ttgcaacttt tctcatataa gttctttgtc
    18361 ttgctattag ttttccttag tagtatacta aggtagtaat cattaagaag tggttacaaa
    18421 aaataatgaa tgaggtaaag aaaatggtag aattgaaaaa agaagcagta aaagacgtaa
    18481 catcattgac aaaagcagcg ccagtagcat tggcaaaaac aaaggaagtc ttgaaccaag
    18541 ctgttgctga tttgtatgta gctcacgttg ctttgcacca agtgcactgg tatatgcatg
    18601 gtcgtggttt ccttgtatgg catccaaaaa tggatgagta catggaagct cttgacggtc
    18661 aattggatga aatcagcgaa cgcttgatta cactcggtgg aagcccattc tctacattga
    18721 cagagttcct tcaaaatagt gaaatcgaag aagaagctag tgaataccgt aatgttgaag
    18781 aaagcttgga acgtgttctt gttatctacc gttacttgtc agaacttttc caaaaaggtt
    18841 tggatgtcac tgatgaagaa ggtgacgatg tgacaaacgg tatctttgca ggcgctaaaa
    18901 ctgaaacaga taaaacaatt tggatgcttg cagccgaact tggacaagca cctggtttgt
    18961 aagaaataag gaaacataga taaatctgta ggaaatttct tacagatttt ttctattttg
    19021 taagctattc caaaccagtc tttttttgag ttttttgata aaatagtact atcagtgaaa
    19081 aggatggaag tatgactaag aaaatcgtag ctatttgggc ccaggatgaa gagggtgtga
    19141 ttggtaagga aaatcgtctg ccttggcatt tgccagcaga attgcagcac tttaaagaaa
    19201 caactctgaa tcatgctatc ttgatggggc gtgtgacctt tgatgggatg gggcgtcgct
    19261 tgcttccaaa acgggaaacc ttgattttga cgcgtaatcc ggaagaaaag atagatgggg
    19321 ttgctacttt tcaggacgtc cagtctgttc ttgactggta tcaggctcaa gaaaagaatc
    19381 tctacattct tggtgggaag caaatttttc aggcttttga accttacctt gatgaagtga
    19441 ttgtcactca cattcatgct cgtgtggaag gagataccta tttccctgaa gaacttgact
    19501 tgtctctttt tgagacagtt tcaagcaaat tttacgccaa agatgagaag aatccttatg
    19561 attttaccat ccaataccgc aagagaaagg aactctaatg gaacggagtt tatttggtct
    19621 attcacggct tttctgtgtt tcatctgctt tctggcagga gcacaagctt ttcgtaaaaa
    19681 gcgttacggg ctttctatcc tcctttggtt aaatgccttt accaatctgg tcaatagtat
    19741 tcatgctttt tacatgacct tattttagat agaatgacag tatagaatgg aaggaaatca
    19801 tgtctacaaa tagaaaaaat gatatgatgg tttattgctc attttgtggc aaaaaccaag
    19861 aagaagtaca aaaaataatt gctggcaaca atgcttttat ttgtaatgaa tgcgtggagt
    19921 tagctcagga aatcattcga gaagaattgg ttgaggaagt cttggcagac ttgtctgagg
    19981 tgccaaaacc aattgaactc ctccatatct tgaaccacta tgtaattggt caagatcgtg
    20041 ccaagcgtgc cttggcagtg gcggtttata accactacaa acgcatcaat ttccacgata
    20101 cacgcgaaga gtcagaagat gtagatttgc agaagtcaaa cattttgatg attggcccaa
    20161 ctggttcagg gaaaactttc cttgcccaga ccttggctaa gagcttgaat gtgccttttg
    20221 ctattgcgga tgcgacagct ctgacggagg ctggttatgt gggtgaggat gtggaaaata
    20281 tcctcctcaa actcttgcag gttgctgact ttaacatcga acgtgcagag cgtggcatta
    20341 tctatgtgga tgaaattgac aagattgcca agaagagtga gaatgtgtct atcacacgtg
    20401 atgtttctgg tgaaggggtg caacaagccc ttctcaagat tatcgaggga actgttgcta
    20461 gcgtgccgcc tcaaggtgga cgcaaacatc cacaacaaga gatgattcaa gtggatacaa
    20521 aaaatatcct cttcatcgtg ggtggtgctt ttgatggtat tgaagaaatt gtcaaacaac
    20581 gtctgggtga aaaagtcatc ggatttggtc aaaacaataa ggcgattgat gaaaacagct
    20641 catatatgca agaaatcatc gctgaagaca ttcaaaaatt tggtattatc cctgagttga
    20701 ttggacgctt gcctgttttt gcggctcttg agcaattgac cgttgatgac ttggttcgca
    20761 tcttgaaaga gccaagaaat gccttggtga aacaatacca aaccttgctt tcttatgatg
    20821 atgttgagtt ggaatttgac gacgaagccc ttcaagagat tgctaataaa gcaatcgaac
    20881 ggaagacagg ggcgcgtgga cttcgctcca tcatcgaaga aaccatgcta gatgttatgt
    20941 ttgaggtgcc gagtcaggaa aatgtgaaat tggttcgcat cactaaagaa actgtcgatg
    21001 gaacggataa accgatccta gaaacagcct agaggtgact atggaactta atatacacaa
    21061 tgctgaaatc ttgctcagtg cagctaataa gtcccactat ccgcaggatg aactgccaga
    21121 gattgcccta gcagggcgtt caaatgttgg taaatccagc tttatcaaca ctatgttgaa
    21181 ccgtaagaat ctcgcccgta catcaggaaa acctggtaaa acccagctcc tgaacttttt
    21241 taacattgat gacaagatgc gctttgtgga tgtgcctggt tatggctatg ctcgtgtttc
    21301 taaaaaggaa cgtgaaaagt gggggtgcat gattgaggag tacttaacga ctcgggaaaa
    21361 tctccgtgcg gttgtcagtc tagttgacct tcgtcatgac ccgtcagcag atgatgtgca
    21421 gatgtacgaa tttctcaagt attatgagat tccagtcatc attgtggcga ccaaggcgga
    21481 caagattcct cgtggtaaat ggaacaagca tgaatcagca atcaaaaaga aattaaactt
    21541 tgacccaagt gacgatttca tcctcttttc atctgtcagc aaggcaggga tggatgaggc
    21601 ttgggatgca atcttagaaa aattgtgagg aaaagaaaat ggcaaaaaca attcatacag
    21661 ataaggcccc aaaggctatc ggaccctatg ttcaaggaaa aatcgttggc aaccttttgt
    21721 ttgctagcgg tcaagttccc ctatcccctg aaactgggga aattgtagga gagaatatcc
    21781 aagaacagac agagcaagtc ttgaaaaaca tcggtgctat tttggcagaa gcaggaacag
    21841 actttgacca tgttgtcaaa acaacttgct tcttgagcga tatgaacgac tttgttcctt
    21901 ttaatgaggt ttaccaaacg gccttcaaag aggaattccc agctcgttca gctgtggagg
    21961 tagctcgtct tcctcgtgat gtaaaagtcg aaattgaagt catcgcagag attggataag
    22021 ctagttgaag tttggtgttg ccaaacttct tttgatataa ggagaaaaag atgacaaaga
    22081 aacaacttca cttggtgatt gtgacaggga tgagtggcgc agggaaaact gtagccattc
    22141 agtccttcga ggatctaggt tatttcacca ttgataatat gccgccagct ctcttgccta
    22201 agtttttgca gctggttgaa attaaggaag acaatcctaa gttggccttg gtagtggata
    22261 tgcgtagccg ttctttcttt tcagagattc aagctgtttt ggatgagttg gaaaatcaag
    22321 atggtttgga tttcaaaatc ctctttttgg atgcggctga taaggaattg gtcgctcgtt
    22381 acaaggaaac cagacggagt cacccactag cagcagacgg tcgtatttta gatggaatca
    22441 agttggaacg tgaactcttg gcacctttga aaaatatgag ccaaaatgtg gtggatacga
    22501 ctgaactcac tccacgtgag ctgcgcaaaa cccttgcaga gcagttttca gaccaagaac
    22561 aagcccagtc tttccgtatc gaagtcatgt ctttcggatt taagtatgga atcccgattg
    22621 atgcggactt ggtctttgat gtccgtttct tgccaaatcc ctattatcta ccagaactga
    22681 gaaaccaaac gggtgtggat gaacctgttt atgattatgt catgaaccat cctgagtcag
    22741 aagactttta tcaacattta ttggccttga ttgagccgat tctgccaagt taccaaaagg
    22801 aaggtaagtc cgttttgacc attgccatgg gatgtacggg tggacaacac cgtagtgtgg
    22861 catttgctaa acgcttggcg caggacttat ccaagaattg gtctgttaat gaagggcatc
    22921 gcgacaaaga ccgcagaaag gaaacggtaa accgttcatg agaaaaccaa agataacggt
    22981 gattggtgga gggactggaa ttcccgtcat tctaaaaagt ctgcgggaaa aagatgtgga
    23041 aatcgcagct atcgtgacgg tggcagatga tggtggttct tcaggtgaac tccgaaaaaa
    23101 tatgcaacag ttgacaccgc caggtgatct tcgtaatgtc cttgtggcca tgtcggatat
    23161 gcctaagttt tatgagaagg tctttcagta tcggttctct gaggatgccg gagcctttgc
    23221 tggccatcca ttgggaaatc tcatcattgc tggcttgtca gaaatgcagg gttcaaccta
    23281 taatgccatg cagttattga gcaaattttt ccatacaaca gggaaaattt atccttccag
    23341 tgaccatcct ttgacccttc atgcagtctt tcaggatggg acagaagtgg ttggagagag
    23401 tcatattgta gaccatcgag gcataattga caatgtctat gtgactaatg ctctaaacga
    23461 tgatacgcct ctggccagcc gtcgagtagt gcagaccatc cttgaaagtg acatgattgt
    23521 cctagggcca ggttccctct ttacctctat tttgcccaat atcgtgatta aggaaattgg
    23581 gcgggctctt ttggaaacca aggcagaaat tgcctatgtc tgcaatatta tgacccaacg
    23641 tggagagacg gaacacttta cagatagcga ccacgtggaa gtcttgcatc gtcaccttgg
    23701 tcgccctttt atcgacactg tcttggtgaa tattgaaaaa gtgcctcaga aatacatgaa
    23761 ttccaaccgt tttgatgaat acttggtgca agtggaacac gattttgtag gtctttgtaa
    23821 gcaagtttcg cgcgtgattt catctaactt ccttcgtctg gaaaatggcg gtgccttcca
    23881 cgatggagat ttgattgtgg acgagttgat gcgcattata caggtgaaaa aatgagtttc
    23941 acagtagcag taaaagaaga aatcctgggc caacaccatc tgagccggca tgaattatct
    24001 gccattatca aaatgtctgg tagcatcggt ctctcgactt cgggcttgac tttgtcagtt
    24061 gtgacagaaa atgccaaact ggcccgtcac ctctatgagt cctttctcca tttctatgaa
    24121 atcaaatctg aaattcgtca ccaccaacgg agcaatcttc gcaagaatcg cgtctatacc
    24181 gtttttacag atgaaaaggt gcaggatttg ttaagtgatt tgcacttggc agactctttc
    24241 tttggcttgg aaacaggtat tgatgaggcg attttatcgg atgaggaagc aggtcgtgcc
    24301 tatctctgtg gcgctttctt ggcaaatggg agcattcgtg accctgagtc aggcaagtac
    24361 cagttggaaa tcagttctgt ttatctggac cacgcgcaag gaattgcctc ccttctccaa
    24421 cagtttttac tggatgccaa ggtgcttgag cgcaagaagg gggctgtgac ctatctccag
    24481 cgagcagaag acattatgga cttcttgata gtaatcggag ccatgcaggc acgtgatgat
    24541 tttgagcggg ttaagatttt gcgagaaact cgtaacgacc tcaatcgggc taataatgcc
    24601 gagacagcta atatcgctcg gacagtttct gccagcatga agaccattaa caatatcagt
    24661 aaaatcaaag atatcatggg cttagaaaat ttgccagtag atttgcagga agtggcgcaa
    24721 ctgaggattc agcacccaga ctactctatc cagcagttag cagatagcct cagcacccct
    24781 ctgaccaaaa gtggtgtcaa tcacagactc agaaaaatca ataagatagc cgatgaatta
    24841 taaaaccacg aatcctatgt gactcgtggt tcttttttat aaactagtag agtgttttgg
    24901 ttgtactttt tgttcagggt caatgtagtt gatagcgttg ttgacagcag ttggagcttc
    24961 tccgaggcct gtcgcaatca gatcaatttt tccgtcatag tagcagcagt caccgatagc
    25021 atagatacct gcttggctgg attcctgttt gctgttgacg ataatcttgt gacggttgag
    25081 gtcgagcccc cagtttttaa ggttaccgac agaagatttg aaaccatagt tgacaaagag
    25141 gtggtctagg tcaatggttt cagtttcatc agatttgact tttgtgattt caagtttatc
    25201 aagtgttttt ccatttccaa ggagttggct aggggcgaat ggtgtcttga tggttacaga
    25261 tgattcttgc aaggcttgaa cactgtgttc caaggcacgg aaattatctc tgcggtgaac
    25321 aagggtagtt ggtgcgattt tttcaaaagc caaagcccaa tccacagccg agtctccccc
    25381 accaagaatc gtcactttct taccagcgta ttgctgaatg ttagaaacgt ggtagtggat
    25441 attttcatag ccctcaaccc cttcaagttc cagcggacgt ggtttgaagg caccgccacc
    25501 catagcgatg atgactgttt tagtcaagtg acttccttta gaagttgtga tggcaaattc
    25561 ttcttcttgt ttgtcaatct caagaaccgt ttcattgaga tgaatagggg tatcaaatcc
    25621 atttagctgt tcaatcaagc ggttagtcaa ctcttctcca gtcaggtttg ggaagcctgg
    25681 tacgtctagg atttcctttt cagggtagag aatagcaggt tgtccaccta gctggggaag
    25741 agagtcgatg atttgaacct tggcttggcg taggtgggca taaaaggctg caaaaagccc
    25801 gacaggacca ccacccacaa tggtaatatc atagagttga gacatagttt ctcctttgtt
    25861 ttttctagtc agtttatttt atcatatttt tgttcaatgt aaactggact aggataggga
    25921 aaaaaatgcc agaaaatggt ataataggac gaaagtgttt tgatagggag gatatcaggg
    25981 atgaattttc aacaattatc caatctgcaa tattggacca gtttgtttgc aagtccatgg
    26041 acgatagcta tcaatctgat tgatattttg attgttgctt atattttata ccattttaca
    26101 aaagctattg caggaaccaa gattatgatt ttggtacgtg gagttttggt gtttatttta
    26161 gctcaaatcc ttgcaaatat gattggtttg actacgattt cttggttaat caatcaaatt
    26221 attacttatg gggttattgc ggcggttgtt atcttctctc cagagattcg gactggtttg
    26281 gaacgtttgg gaagagcgac agatttcttt tccaatgccc ctattagtgc tgaggaacag
    26341 atgattcgtg cctttgttaa gtctgttgaa tacatgagtc ctcgtaaaat cggggccttg
    26401 gttgctattc agcgtgtacg taccttgcag gagtatattt cgacaggaat tcccttggat
    26461 gctaagattt ctgcagaact tctcattaac atttttattc ccaacactcc cctacatgat
    26521 ggtgcggtga ttatcaaaga agaacgtatc gctgtgacgt ctgcctatct gcccttgaca
    26581 aaaaacacag ggatttccaa ggaatttggg accagacacc gggcggctat cggtttatca
    26641 gaagtctcag atgccttgac ttttgttgta tcagaggaaa cgggaggaat ttcgataacc
    26701 tataatggaa ggtttaagca caacctaaca cttgatgaat ttgaaacaga attacgtgaa
    26761 atcttacttc caaaagagga agtgggtctt agttttaaag aacgattgct aggaggatgg
    26821 aaacatgaaa aaaaatagtt tatatatcat atcctcactc ttttttgctt gtgtcttatt
    26881 tgtctatgct acggcgacga attttcaaaa cagtaccagt gctaggcagg taaaaacgga
    26941 aacctatact aatacagtaa caaatgtccc tattgacata cgctataata gtgataagta
    27001 ttttattagc ggttttgctt cagaagtatc agtggtcttg actggtgcaa atcgcctatc
    27061 gctagctagt gaaatgcaag aaagtacacg taaattcaag gttactgctg acctaacaga
    27121 tgccggtgtt ggaacgattg aagttccttt gagcattgaa gatttaccca atgggctgac
    27181 cgctgtggcg actccgcaaa aaattacagt caagattggt aagaaggctc agaaggataa
    27241 ggtaaagatt gtaccagaga ttgaccctag tcaaattgat agtcgggtac aaattgaaaa
    27301 tgtcatggtg tcagataaag aagtgtctat tacgagtgac caagagacat tggatagaat
    27361 tgataagatt atcgctgtct tgccaactag cgaacgcata acaggtaatt acagtggttc
    27421 agtacctttg caggcaatcg accgcaatgg tgttgtctta ccggcagtta tcactccgtt
    27481 tgatacaata atgaaggtga ctacaaaacc agtagcacca agttcaagca catcaaattc
    27541 aagtacaagc agttcatcgg agacatcttc gtcaacgaaa gcaactagtt caaaaacgaa
    27601 ttaaaaatag aaaaggattt tataacaatg ggtaaatatt ttgggactga tggagtccgt
    27661 ggagaagcta acctagaact aacaccagaa ttagccttta aactaggacg ttttggaggc
    27721 tatgttctta gtcaacatga aacggaagcg ccgaaagtct ttgtaggacg tgacacacgt
    27781 atttcagggg aaatgctgga atcggccttg gtggcaggtc tcctttcagt agggattcac
    27841 gtatacaaac ttggtgtcct tgcaacacca gcagtagctt acttggttga aactgaagga
    27901 gcaagtgccg gtgtcatgat ttctgctagc cacaacccag cccttgataa cggaatcaag
    27961 ttctttggcg gtgatggctt caaactagat gatgaaaaag aagcagaaat tgaagccttg
    28021 ctagatgctg aggaagacac tcttcctcgt ccaagtgcag aaggcttagg aatcttggta
    28081 gattatccag aaggcttgcg taagtatgaa ggataccttg tttcaactgg aactcctctt
    28141 gatggaatga aggttgcctt ggatacagct aatggagcag cttctaccag tgcccgtcaa
    28201 atctttgcag accttggtgc ccaattgacg gttatcgggg aaacaccaga cggtcttaac
    28261 atcaacctta atgttggttc aacacatcca gaagcccttc aagaagtggt caaagaaagt
    28321 gggtcagcta ttggtttggc ctttgatgga gacagtgacc gcttgattgc tgttgatgag
    28381 aatggtgaca tcgtcgatgg tgacaagatt atgtacatca tcggaaaata cctttctgaa
    28441 aaaggacaat tggctcaaaa tacaattgtg acaactgtta tgtctaacct tggtttccac
    28501 aaggccttga atcgcgaagg tattaacaag gcagttactg cagttggtga ccgctacgtt
    28561 gttgaagaaa tgagaaaatc aggctacaac cttggtggtg aacagtctgg tcacgttatc
    28621 ttgatggatt acaataccac aggtgatggt caattatcag cagttcaatt gactaaaatc
    28681 atgaaggaaa ctggtaagag cttatcagag ttggcggcag aagtaacgat ttatccacaa
    28741 aaattagtta atatccgagt ggaaaacgtc atgaaggaaa aggccatgga agtgccagct
    28801 atcaaggcca tcatcgagaa gatggaagaa gaaatggcgg ggaacggccg tatccttgtt
    28861 cgtccaagtg gaacagagcc cctcttgcgt gttatggcag aagcgcctac aacagaagaa
    28921 gtagactact atgttgatac catcacagat gtagttcgtg ctgaaattgg gattgattaa
    28981 atcctagaaa actagatgaa aataaaaaat tatggtacaa tagcttataa tattgtagcc
    29041 gatggagaaa gacatgaatc ttaaacgtga acaagaattt gttagtcagt atcattttga
    29101 tgcgcgtaat tttgaatggg aaaatgaaaa tggagctcct gaaaccaagg tggatgtgaa
    29161 tttccaattg ctccaacatg accaagaaaa tcaagtgact tccttgattg tcatcttgag
    29221 ctttatgatt gtatttgata agtttgtcat tagtggaaca atctcacaag taaaccatat
    29281 cgatggccgt attgtcaatg aaccaaatga attgaaccaa gaagaggtgg aaaccttggc
    29341 tcgtccatgt ttgaacatgc tcaatcgttt gacttacgaa gtgactgaaa ttgcattaga
    29401 cttaccagga attaatttgg agttctaata tgaaattagc tgttttcaca gattcctctg
    29461 cttatctcag tgcagagacc ttgcaaagag aagacttgtt tgtcttggat attcctgtca
    29521 atattgatgg tgaggaatat gtcgaaggca tcaatctgtc tgctgaggaa ttttaccaaa
    29581 aaatggctca ggcttctgaa ttgcctaaga ccagtcaacc aagtattgcc aagttagatg
    29641 aaatcttaac ttcgctcaaa gaacaaggct atacacatgc cttggggctt ttcctatctt
    29701 ctggaatttc aggtttttac caaaatatcc agtatatggt cgatgactat gagggcttaa
    29761 ccattgcttt cccagacact ttgattacaa gtgctcccct aggcatcatg gttgaaagcg
    29821 tctttaattg gcgtgatcag ggcgatgatt ttgccagcat tcaggataag ctagccattc
    29881 aaatcagccg tacgtcagcc tttatcatgg tagatgactt ggatcatttg gtaaaaggtg
    29941 gacgtctttc aaatggggct gccattttgg gcaatttgct tagcattaag ccaatccttt
    30001 attttaacga tcaaggtgtg attgaagttt acgaaaaagt tcgtactgaa aagaaggcca
    30061 ccaagcgctt aattgaaatt atcaaggaaa caacggcttc aggtcaatac cgggtcattg
    30121 tcattcatgg gaatgctcct gaaaaggctg aagaattgcg tcagcatttg cttgattttg
    30181 gcttgggttc ggatgtttca cttgctacat ttggtagtgt cattggaacg cacctaggag
    30241 caggaagtat tgctctgggt tatattccag tgatttagtt ggcgcttcta ggctagttaa
    30301 gatgccttgt atcttagcaa ttgaacacgg actacctgct tcttgaaaaa agatgcctgt
    30361 cttgcctttc gtggaaagtc agtgccattc cctatttttc aggggcagct aaggtccttt
    30421 gtatcttgat aattgaacac gcctggaacc ctgtgtgaaa aagatagttc ttccaagaag
    30481 tagacacttc ttgattggaa ttcctatttt cactttgtgt tcttacggac tttgtatctt
    30541 agacaggagt agagatgagt attcgagtaa ttattgccgg ttttaaggga aagatgggcc
    30601 aggctgcttg tcagatggta ttgactgatc cagacttgga cttggtagca gttttggatc
    30661 cttttgagtc tgagtcagaa tggcagggta ttcctgtttt caaggataag gctgatttag
    30721 cttgttttga agcggatgtc tgggtagatt ttactactcc agctgttgcc tacgaaaata
    30781 cacgttttgc tcttgaaaat ggctttgctc cagtagttgg aacgactggt ttcacgagtg
    30841 aagaaattgc agagctaaaa gaattttctc gtacccaaga cttgggtggc ctgattgccc
    30901 ctaactttgc cttgggtgct gtcttactca tgcaatttgc gacgcaggct gccaaatatt
    30961 tcccaaatgt ggagattatt gagctccatc atgacaagaa aaaggatgct ccgagtggaa
    31021 cagccattaa aacagctgag ttgatggcag agattcgaga gtcaattcag caaggtgcag
    31081 cagatgagga agagctgatt gctggtgctc gtggtgctga ctttgatggt atgcgcatcc
    31141 actcagttcg tttgccaggt ttggtagccc atcaggaagt catctttggc aatcaaggag
    31201 aaggattgac cctccgtcat gactcctatg atcgcatctc cttcatgaca ggagtcaatt
    31261 tgggaattaa agaagttgtc aagcgtcatg agcttgtcta tggattagaa cacttattat
    31321 gagattaatg caaatgcctt ctgaatttca gaaggcttta ccagtattag aaaaaattaa
    31381 agaagcaggc tttgaggctt attttgttgg gggctctgtt cgagatgccc ttctccatag
    31441 ccctatccac gatgtggata ttgcgacgtc ttcttatcca gaagagacca agcagatttt
    31501 tccgcgaaca gccgatatcg gaatcgagca tggaaccgtc ttggtcttag atggggatga
    31561 ggagtatgag gtaacaacct ttcggacaga ggatgtctat gtggactatc gcagacccag
    31621 tgcggtttcc tttgtgcgct cgctagaaga agacctcaaa cgccgtgatt tcacagtcaa
    31681 cgcctttgcc ttggatgaga caggagaaat cgttgacttg ttccatggtt tagaagattt
    31741 ggaaaagcaa gtcttgcgag cagttggagt ggctagtgag cgtttcaacg aagatgcttt
    31801 acggattatg cgtggtttcc gttttcaggc tagtcttggt tttgcacttg aaccagaaac
    31861 atttaaagct atgaagacct tgacgccgct tttggagaac atttctgtag agcgtacctt
    31921 cgtcgagttt gataaactct tgctggctcc attttggaga agggggttgg cttccatgat
    31981 tgagagtcaa gcttatgact atctccctga tatggcatct agccaggaca agctcaacag
    32041 actgtttgat ttggagactg attttacttt tgaatcctct gaacaagcct gggcggcttt
    32101 actatgggct ttggagattg aaaatgcgca gtcatttttg aaatcttgga agacctcacg
    32161 ccagtttgcc aagcaagttc aggatttgct gattattttg gctctgcgtg aaaatggaga
    32221 attgagcaag cgagattgtt atcgctttga catagatttg cttttacagg ctgaaaatct
    32281 tcgtcaagct caaggaaaag aagtcaaccc acaagccatc acagaaaaat accaaagctt
    32341 gactatccat gacaagaaag agattcagat taatggcggt attttgatca aggaatatgg
    32401 ctatcagcca ggcccagact tgggagagat tttaacagag attgagtttg ccattgtcga
    32461 tggagaattg gagaataatc gtgaagccat ccatgcttac ctgagggaga aaaaatgagt
    32521 gattttatcg ttgaaaaact aagtaaatct gttggtgaca agaccgtttt tagggatatt
    32581 tcctttatta tccatgactt agacagaatt ggtttaatcg gtgtcaatgg gactggcaag
    32641 accacccttt tggacgtcct ttctggtgtt tctggctttg atggggatgt cagtcctttt
    32701 tcagctaaaa atgattacca gattggttac ttgactcagg atcctgattt tgatgataga
    32761 aagacagttt tggatacgat tctatctagt gaactcaagg aaatccagct cattcgtgag
    32821 tatgaattga ttatgctcga ctatagcgag gacaagcagg cgcgtttgga acgtgtcatg
    32881 gcagagatgg actctctcca agcttgggaa atcgagagtc aggtcaagac cgttcttagc
    32941 aaattgggca ttcaagactt atctactcct gttggggaat tgtcaggtgg tctgagaaga
    33001 cgggtacagt tggcacaagt cttacttggc aaccacgacc tcttgctttt ggatgagccg
    33061 accaaccatc tggatattgc gattattgag tggctgaccc tctttttgaa aaattctaag
    33121 aagaccgtcc tttttatcac tcacgatcgt tatttcttag acgctttgtc aacacggatt
    33181 ttcgagttgg agcgagcagg cttgacagaa tatcagggca attaccagga ctatgttcgc
    33241 cttaaggcag aacaggacga gcgcgatgca gctctacttc ataaaaaaga acaactctac
    33301 aaacaagaac tggtctggat gcgcagacaa ccgcaggcac gtgcgaccaa gcaacaagct
    33361 cgtatcaatc gtttccatga tctgaaaaag gaagtttcag gcagtagtgc tgagacagac
    33421 ttgactatga actttgaaac cagtcggatt gggaagaaag tcatcgagtt tcaggctgtt
    33481 tcctttgcct atgaaaataa gcccattttg caagatttta atctcttagt tcaggctaaa
    33541 gaccgtattg gaattgttgg ggacaatggt gttggaaaat caaccctact taacctgatt
    33601 gcaggaagtc ttgagccgac agcaggacaa gttgtgattg gggaaactgt tcgcatcgcc
    33661 tatttctctc aacaaattga gggtttggat gaaagcaagc gtgtgatcaa ttacctgcag
    33721 gaagtggcag aggaggtcaa gaccagtggt ggttctacga cttccatcgc tgagttgctg
    33781 gagcaattcc tcttcccacg ttcgacgcat gggaccttga ttgagaaatt gtcagggggt
    33841 gagaaaaaac gtctttatct cctcaaactg cttttggaaa aaccaaatgt tcttctttta
    33901 gacgagccaa ccaatgacct agatattgca actttgacag tcttagagaa tttcttgcaa
    33961 ggttttgcag gtcccgtttt aacagtcagt cacgaccgct atttcttgga taaggtagcg
    34021 accaagattc tcgcttttga ggatggcaag attcgtcctt tctttggtca ttacaccgac
    34081 tatcttgatg aaaaagcttt tgaaacagat atggccaatc aagtgcaaaa ggccgaaaag
    34141 gaaaaagtgg tcaaggttcg agaagacaag aaacgcatga cctaccaaga aaagcaggag
    34201 tgggcaagta ttgaaggtga tattgaaacc ttggaaaaac gtatcgctgc tattgaagag
    34261 gaaatgcagg ctaacggctc tgactttggt aagctggcta ctctccaaaa agaattggat
    34321 gagaaaaatg aagcactcct tgaaaaatac gaacgctatg agtatctcag tgaatttgat
    34381 agttaatact attcgaaaat caaagtgtaa actatgtcgg cttcacattg ccgactcaag
    34441 tacagcctgt ggccggcttc ctagtttgca ctttgatttt tattgagtat aaaagaatag
    34501 aaaaatccca tctcatgaac ggatttctct attctttttt ggtttcttga tgaaagatat
    34561 tttgccaggt ttcgtggcga cgccagatac tggtatggat gataccatct aactcatagc
    34621 agatgagttt ggttttttga ctgatggaag taatttgaat gtccttgata gcagaattta
    34681 actctttttt ggtcttataa gcctctttat ccatctgctc tccatcttgg cgaatataga
    34741 caaaatcatc agtcaagagt tcttctagtt ggtttccttg gtcaatcaat tgttcacgca
    34801 taagcaattt tttatagaca ttgtctaaaa tttcatcctc agggataggt gctggttcga
    34861 tatggacatc ggtatcaaag acgccaaaac gattctccag catagactcg acctgatccg
    34921 cgatttcatg gctttcaaaa acagacaagt caggattcat ctctagtgta atatccaggt
    34981 agatgttgct accgtaggtg cgacctcttt gcgatttgac cttgctgatt ttgggaattt
    35041 ccatgatagc cttttggtag tcctcgagca ggcggtcgtc aaagccatct gaaagactaa
    35101 aggaagactc gatgaagata tcataggcag tcttcaagat aaagaaagtg atgatgatag
    35161 caaccagttt atccacaatc ggataattga aactactagc taggatggca atggcggttc
    35221 caagtgaggt aacagcgtca gaaagattgt ccttagcagc tgctttcagc gccttggagt
    35281 tggatttctt actgaggcga gtattgtaga gatagaccac aaacataatc gctgcagaaa
    35341 tgattcctag agttgcacca agaggatcaa tgaccgtttc ttcccgactg agaatctttt
    35401 gaatggtatc tcttagaaca tcgaaaccga catagaacat gatgatagaa gtgatcaagc
    35461 ttgccaaatc ttcaatcttc caatgaccaa aacggtggtc acggtctgca ggctggcgcg
    35521 ccatccgaat cccgattaag agggccacat ttccaatgat gtccgatacg ttattaaaac
    35581 catcggccac caaactggat gaatgaagga gatgaccagt tgctaatttg gctgcagaca
    35641 agatcaaata ggtcgaaata ctgataatgg ctccacgctc agctaacttg agatttgaga
    35701 tagattgctt cattcaactt cctttctagt cacatagcat tctaccatta tactggtttt
    35761 caaggaaaaa ttcaaataag gcagttttta ctctttgaaa actccccaaa atttggtata
    35821 atagtactac tcaagggagt agctggcaga aacctgtgat agtgtcgtca ttccgaattt
    35881 tatgctgaaa agtatgcttt ccggccctat cttaaacagc gagacttgtt atgattaaca
    35941 ggtctctttt tgtttgtcgt gaaaagatat gacagaaaga gagtctgttt tgcacacaat
    36001 gtcaaggagg agacacatgt caaaagaaca aaaacgccaa gcgttttata ctcagagccc
    36061 tgaagaggtc ttgcaggctg tggatgcgac cgagcaaggt ttgtcgtcaa gtgaggcgga
    36121 aaagcgcctt gtcgaatttg ggcacaatga actcgaagaa ggcgagaaac gatcaatctt
    36181 ggtcaaattc atcgagcaat ttaaggattt gatgattatc atcctagttg cggcagcaat
    36241 cttgtcagtc gtgacttctg gtggggaaga tatcgcagat gccattatca tcctagctgt
    36301 ggttatcatc aacgctgcct ttggtgttta ccaagaagga aaagctgaag aagctattga
    36361 agccctcaaa tccatgtcta gtccagttgc ccgcgttctt cgtgatggac acatggcaga
    36421 gattgactct aaagaattgg taccaggcga tatcgttgcc cttgaagcag gtgacgtggt
    36481 accagcggac ctacgtttga tagaagccaa ctctcttaaa attgaagaag cagccttgac
    36541 aggtgaatct gtaccagtcg aaaaagactt gtcagtcgag cttgcgacag atgctggtat
    36601 tggtgaccgt gtcaacatgg ccttccaaaa ctcaaacgta acctatggtc gtgggatggg
    36661 tgttgttgtc aatacaggta tgtacactga agttggtcat attgctggta tgcttcaaga
    36721 tgcggatgag actgatacac cactcaaaca aaacttgaac aacctttcta aggtcttgac
    36781 ctatgctatc ttggccattg cccttgttac ttttgtagtg ggtgtcttca ttcaagggaa
    36841 aaatccactt ggtgagttgt tgacttctgt tgcccttgcc gttgcagcca ttccagaagg
    36901 acttcctgct atcgttacca tcgttctttc tcttggtact caagttttgg ccaaacgaca
    36961 ttccatcgtt cgtaagttgc cagcagttga aacacttggt tcaactgaaa tcatcgcttc
    37021 tgataagact ggtacgctga ctatgaacaa gatgacagtc gaaaaagtct tctacgatgc
    37081 ggttctacat gactcagctg atgatattga actaggtctt gaaatgccac tacttcgttc
    37141 agttgtcttg gccaatgata cgaaaatcga tgtggaaggt aacttgattg gtgacccaac
    37201 cgaaacagcc tttatccaat atgccttgga caagggctat gatgtcaaag gtttcttaga
    37261 gaaatatcct cgtgtagctg aattgccatt tgactctgac cgtaagctca tgtcaacagt
    37321 tcacccattg ccagatggtc gtttccttgt agcagtcaag ggtgcgccag accaactctt
    37381 aaaacgttgt cttcttcgtg ataaggctgg ggatattgct ccgattgatg agaaggttac
    37441 aaatctcatt catacaaaca attctgaaat ggctcatcaa gccttgcgtg tccttgcagg
    37501 tgcttataag attatcgata gtattccaga aaatctcact tctgaagagc ttgaaaatga
    37561 tttaattttt actggtttga ttgggatgat tgaccctgaa cgtcctgaag ccgctgaggc
    37621 tgttcgtgtg gctaaggaag cgggaatccg tccaattatg attacaggtg accaccaaga
    37681 cacagcggaa gccattgcca aacgtttggg aatcattgac gcaaacgata cagaaggtca
    37741 cgttttaact ggtgctgaac tcaatgaact gtcagatgaa gaatttgaaa aagtcgttgg
    37801 tcaatactct gtttatgccc gtgtgtctcc agaacacaag gttcgtatcg tcaaggcttg
    37861 gcaaaaacaa ggtaaagtcg ttgccatgac aggtgacggt gtcaatgacg cgccagctct
    37921 gaaaacagcc gatatcggta tcggtatggg aatcactggt acagaggttt ctaagggggc
    37981 ttctgatatg attcttgcag atgataactt tgcgactatt atcgtcgcag tggaagaagg
    38041 acgtaaggtc ttctcaaaca ttcaaaagac tattcagtac ctactttctg ctaatactgc
    38101 tgaagtatta accatcttcc tatcaacctt gtttggttgg gatgtcttgc agccggttca
    38161 tcttttgtgg atcaacttgg taacggatac cttcccagct atcgctcttg gtgttgaacc
    38221 tgcggagcct ggtgtcatga atcataaacc acgtggacgc aaggcaagct tcttctcagg
    38281 tggtgttttg agttctatca tttatcaagg tgtactccaa gcagctcttg ttatgagtgt
    38341 ttatggcctt gcgattgctt acccagttca tgtgggtgac aatcatgcta ttcatgcaga
    38401 tgccctaacg atggcctttg caacccttgg tttgattcag ctcttccatg cctacaatgt
    38461 caagtctgtc taccaatcca tcttgacagt tggcccattc aagtctaaga cctttaactg
    38521 gtccatcttg gtatctttta tccttctcat ggcaacaatc gttgtagaac cgcttgaagg
    38581 aatcttccac gtaaccaaac tagacttgtc acaatgggga attgttatgg ctggaagctt
    38641 ctcaatgatt atcatcgtcg aaatcgttaa gtttattcaa cgcaaactcg gttttgacaa
    38701 gaatgcgatt taagggaggt ttcggatgtc agcatatcaa ttaccgaccg tatggcagga
    38761 tgaagctagt aatcaaggag cttttacggg gctaaacaga ccaacagcag gtgcccgttt
    38821 cgaacaaaac ttgccaaaag gagaacaagc ttttcagctt tattcactgg gaacaccaaa
    38881 tggtgtgaag gttactatct tattggaaga attactagaa gctggtttta aggaagcggc
    38941 ttacgacttg tataagattg ctatcatgga tggggatcaa ttcggctcag actttgtgaa
    39001 gctcaatcca aattccaaga ttccagcctt attggaccag tcaggtactg aaaacgtaag
    39061 agtctttgag tctgctcata ttcttcttta ccttgctgag aaatttggag cctttttacc
    39121 aagtaatcct gtggaaaagg tagaagtttt gaattggcta ttctggcaag caggtgcagc
    39181 accttttcta ggtgggggat ttggacattt cttcaattat gctcctgaaa aattggaata
    39241 tcctattaac cgttttacga tggaagtgaa acgccagttg gatttattgg ataaggaatt
    39301 ggctcagaaa ccttatattg caggcaatga ctatacgatt gcagatattg ctatctggtc
    39361 ttggtatgga cagttagttc aaggaaatct ttaccaaggt tctgcaaaat tcttggatgc
    39421 ctcaagttat caaaatctag taaaatgggc agaaaaaatt gccaatcgtc cagctgttaa
    39481 gcgtggattg gaagtaactt atacagaaat taaatagcaa aaaagtcatc ttcggatggc
    39541 tttttgctac agttgaggga aagggtttgc agttatcggc ttttgtgcta taattgctat
    39601 aatatagtaa aaagcaagag gagtgtgagg aagtggaaaa gaaaattgtg aaggatatct
    39661 tatttttatc tcaagtgtct cagccggcaa gtcaggagga cctttatctt gccagagatt
    39721 tgcaggatac actcttagca aatcgtgata cctgtgttgg tctagctgcc aatatgattg
    39781 gggtgcagaa gcgcgtgatt atctttaatc ttggcttggt tcctgtggtc atgtttaacc
    39841 cagtgcttct gtcctttgaa ggatcctatg aggcagaaga aggctgtttg tccttggtag
    39901 gtgtgagatc aactaagcgt tatgaaacca taaggcttgc ctatcgtgac agcaagtggc
    39961 aggaacagac cattaccttg acaggcttcc cagctcagat ttgccagcat gagctggatc
    40021 acttggaagg acgaatcatt taggaggaaa gcaaatgaaa cgaatagtct ttgaacttat
    40081 ttttatcgca acgacctggt atatcttttt accgcccctt aacctgacca gctgggaatt
    40141 tctcttcttc ctctgtgggc atttgttagt tgtggcaata ttatttggct ttggcaaggg
    40201 gataaacctt gtcaaaacgg ttcatgtgcg ccacggtaag gcggaagctg ccttaaatct
    40261 tgagggtttc aaaatcaatc ggttagggaa aattctgtta gcttcgattg gaggaattct
    40321 tctcttggca gctttggttt ccttggtaac ttccagcatg tttcaggcta aaaattatgc
    40381 caatgtagtc acggttacgg aaaaagactt tactgaattt cctaagagtg acaccagtaa
    40441 ggttcctatc ctagatagaa gtactgctga aaaaattgga gaccgctact tgggttccct
    40501 aaccgataag gtgtcgcaat acgtagcggc agatacctat acccaattga caattgatgg
    40561 gaaaccttat cgggtcacac cactagaata tgcagaccct atcaaatggt ttaacaatca
    40621 agccaaggga atcggtgagt atattaaggt ggacatggta actggaaatg cggatttggt
    40681 ggacttgaag acaccaatca agtattcaga ctcggagtat tttaaccgtg atgtcaaacg
    40741 tcacctgcgc ttgaagtacc cgaccaaaat ctttaaaact ccatcttttg aggtggacga
    40801 tgagggcaat cctttctatg tagcaacggt ttaccaaaag caatttggac ttgctgttcc
    40861 tcgtcctgct tcagtcatta tcttggatgc tacaaatgga gaaaccaagg aatacagctt
    40921 atcagatgtt ccagaatggg tggacaggat ctatccagca gaggaaacca ttgagcaaat
    40981 caactacaac ggcaagtaca aggacggttt cttgaatgcc atgatttcca agaaaaacgt
    41041 gacccagact accaatggct ataattactt gtctatcggt aatgacatct atctctacac
    41101 aggtgtgacg tcggctaatg cggatgagag taatcttggt ttcatccttg aaaatatgcg
    41161 aacaggagaa atcactaagt atagcttggc ttctgcgaca gaagaatcag cccgtgaatc
    41221 agcagaaggt gctgttcagg agaaatccta caaagcaacc ttcccaatcc tcatcaacct
    41281 caatgacaag cctctctaca tcatgggctt gaaggacaat gctggcttgg tcaaagagta
    41341 cgccctggta gacgcagtcg agtaccaaaa tgttatcgtt gctactacag tggaagagat
    41401 gctcagcaag tatgccaata aaaacgacct tgaaattgac aatgcaacga cagaaagcat
    41461 caatggagta gtagcagacc tcaaatcagc tgttatcaag ggagacactg tctacttctt
    41521 taaagttgat ggcaagatat acaaggtcaa ggcttcagta tccgatgacc ttccttacct
    41581 tgaaaatggt aaaaccttcg aaggtcaagt aggaaaagac aattatctca agacctttaa
    41641 gctacggtaa aaataggttt ttttcagaaa gtatatgtta taataaggta aattaagcct
    41701 aatggaggac aaagaaatgg gtttttattt gatggttgct tcaatgctac tcggactgct
    41761 cgctttgaag ataggttttt ctcagttcaa ggagaaaaaa gataaattct tatctatctt
    41821 aacaagttta gctggcacag cccttgttct cgtggctgtc tggttaggat ggcccaaata
    41881 aatagaaaaa cctcggtcaa accgaggttt ttcaaatgaa tttcttggtt gtggctaaaa
    41941 aatatgctac actatcaata tgaaaatttt aatcccaaca gcaaaagaaa tgaacacaga
    42001 cttgccaagt atcgaggcaa ttcctttaaa accagaaagt caggccgtgc ttgatgcctt
    42061 ggctctctat tctgccagtc aattggagag tttctacaag gtatcagctg agaaagcggc
    42121 ggaagaattt caaaatatcc aagctttgaa aaggcaaact gctcaacact atccagcctt
    42181 gaaacttttt gatgggctta tgtaccgcaa cattaagaga gataagctga ccgaggcgga
    42241 acaagattat cttgaaaatc atgttttcat tacctcggct ttgtacggtg ttgttccagt
    42301 cttgtcaccc atggctcctc accgtttgga ttttttgatg aaattaaaag tcgctggtaa
    42361 gactttgaag agccattgga aggcagccta tgatgaaact ctgaagaagg aagaagtgat
    42421 tttctctctc ttgtcatcag agtttgagac tgtattttct aaggaaatca gagcaaagat
    42481 ggtgacctta aaattcatgg aggatagagg cggtcagctg aagattcact caactatctc
    42541 caagaaagcg cgcggggcct ttctaacagc tttaatagaa aatcaagtac aaactgtggg
    42601 ggaagcacgt cgcttgaact ttgctggatt tgtttaccga gaagatttgt cacaaccaca
    42661 gggattggtt tttgtaaagg aagtatagaa atcagatatt ttgtatttgg caatatgtat
    42721 catcagctat tttagtttat aaatgagaaa aaagcgaaca agctagtctt ctgagtgtca
    42781 gaaaagtagt cttgttcgct tttattatgt tatactcttc gaaaatctct tcaagccacg
    42841 tcagtgtcgc cttaccgtat atatgttact gacttcgtca gttctatcta caacctcaaa
    42901 gcagtgcttt gagtagcttg cggctagctt cctagtttgc tttttgattt ttattgagtg
    42961 ttagttactt gatagcttcg accaagtctt gagcttgttt ttcaagtgag tttaggactg
    43021 tttcttcaag aaccaatttt ccgtctgccc aggcagagtc attaacacgt gcagcagtga
    43081 aatcaccaac gccttgtgta cggataaatg gcaagaggtc tttgtagata gcgaaaagtt
    43141 gatcgtgccc tgcattggct acagatgata ctgtgacaaa cttgtcttga agggcagaaa
    43201 cgccacgtgt atcagacaag tcaagggcac gagatagcca gtcaagcaag tttttcactg
    43261 taccagggat agagaagttg tagactggag agaaaatcca gatagcatcc gcaacgagaa
    43321 ctgcttcacg agcagcagct acagctggat gtgttggaac ttccaaatct tggctgaaga
    43381 gaggaagggc tgaataatca aggtagctaa cttccgcttt accagcaagt gctttctcag
    43441 cttcgagcgc catttggtgg ttgaaagaac cttgacgtag tgatccgacg ataaataata
    43501 cttttttaga catgatgtgt ctcctttttc ttaaaatttc gagaactctc tcgttgttat
    43561 aaaatatatt acaacaaaac aaaagaactt gcaagaaatt tgctcagagt ttatttgaaa
    43621 attgtaaaat ttcggaaact ctagtcattt gtgactgaaa aagtaagaac tgtttcactt
    43681 tcaaaatcgg ttttgtttga agggagaaat agaattggtt gctcaaagca cagctttgag
    43741 gttgcagata aagctgacgt ggtttgaaga gattttcgaa gagtattctt atattcactt
    43801 gtaataaagc ttaatagatg gtaaaataga cgagtgaaaa aaagacaaaa caaagcaaaa
    43861 aataatctac tgtggcagta tggtctaggg atgacgattt tgtttgtggt tatcagtgct
    43921 tcctttctgt atatggtttc tcttagcatg aaaccctatc aaacagctaa aagtgaagga
    43981 gaaaaattag ctcagcagta tgcaggatta gagcaggccg atcaggttga tttatacaat
    44041 ggcttggaat cttattacag cgttcttggt cgtaataaac agcaagaagc acttgctgtt
    44101 ctgattggaa aagatgatca taagatttac gtttatcagc taaatcaggg tgtttcacaa
    44161 gaaaaagcag aaacggtttc taaggaaaag ggagctggcg aaattgacaa gattatcttt
    44221 ggtcgttatc aagataagcc aatctgggaa gtcaagtcag gatctgattt ttatctagta
    44281 gattttgaaa caggagcatt ggtcaacaag gagggcctat gaaattatcc aaccgtgttt
    44341 tagaaatgga agaaagtgtg actttggctg ctggagcccg tgccaaagca ctgaaggctg
    44401 agggcagaga tattttgtct ctaaccttgg gtgagccaga tttcactact cccaaaaata
    44461 tccaagatgc cgccattgca tcgattcgag atgggcgtgc ttctttttat acagtaacct
    44521 caggtctgcc agagcttaag gcggcggtca atagctactt tgagcgcttt tacggctatt
    44581 ctgtagcgtc aaatcaagtg acagtcgctg cgggagccaa atattctctc tataccttct
    44641 ttatggctgt ggtcaatcca ggtgatgaag tcatcatccc aaccccatac tgggttagct
    44701 atggagatca ggtcaagatg gcagaaggcg ttcccgtctt tgtttctact aaggaagaca
    44761 atcactttaa ggtgaccgta gatcagttag aagcagctcg cactgacaag accaaggttt
    44821 tggtgctgaa ttcgccatct aatcccacag gtatgattta cacccgtgag gaactcttgg
    44881 caattggaaa ctgggctgta gaaaatgata ttctcatcct agcagatgat atctatggcc
    44941 gcttggttta taatggtcat gagttcacac cgatttctag cctatcggaa gcgattcgca
    45001 agcaaacagt ggtcatcaat ggtgtgtcta aaacctatgc catgactggt tggcggattg
    45061 gttatgccgt tggagaagca gacattatcg ctgccatgtc caagattgca ggtcaaacaa
    45121 cttcgaatcc gtcagcagta gcccaatatg cagcagttga ggctctatca ggtgagcaag
    45181 atactgtaga aagcatgcgt caggcctttg aggaacgtct taatactatc tatcccctcc
    45241 ttgcagaggt gccaggattt gaagtggtca aaccgcaagg ggccttctat ctcttcccaa
    45301 atgtcaaaaa ggccatggag atgaaaggct acacggatgt gacagacttt acaactgcta
    45361 tcttagaaga agccgaagtg gccttggtaa caggagctgg atttggagca ccagaaaatg
    45421 tccgcctcag ctatgcgaca gacctagaca cgcttaaaga agcagtcgaa cgcttgaaag
    45481 catttatggg tagtgagaat gattgatcat tttgagatta aggtaaagga tttacaaatt
    45541 tcagaaggat tttataggag ttttctcgct cctttggact ataaaatggc ttttaagact
    45601 agttctctaa ttagttttct atccccgaac agccctcatc ctggtggtga tttttggctg
    45661 actcagggaa cacaagatcc tgttcatttt gcttttttag cagaaaataa ggaagaagtt
    45721 caggcttgtt atgaggctgg cttagaggca ggtgggcgag acaatggggt tcctggttat
    45781 cgaagtgagc atccgattta ttatgctgct tttatgattg acctggatgg gaacaatata
    45841 gaggtggttt gccataaaga ataaaaaaga aaaggaaaaa taatgacaaa acgtgtaacg
    45901 attattgatg taaaagacta tattggtcaa gaagtgacga ttggcgcttg ggttgccaac
    45961 aaatcaggaa aagggaaaat cgctttctta caattgcgtg atggaacagc cttctttcaa
    46021 ggtgtggctt ttaaaccaaa ctttgtcgaa aaatttggtg aagaagtggg acttgagaag
    46081 tttgatgtta tcaaacgctt gagccaagaa acgtctgttt atgtgacagg tattgtcaaa
    46141 gaggacgaac gttctaaatt tggctatgag ttggacatca cagacatcga agtgatcggt
    46201 gaatctcaag actacccaat cacaccaaaa gaacacggaa cagacttttt gatggataac
    46261 cgtcacttgt ggctacgctc tcgtaagcaa gtagctgtgt tgcaaatccg taacgctatt
    46321 atctatgcaa cttatgagtt ctttgacaag aacggtttta tgaagtttga cagcccaatt
    46381 ctttcaggaa atgcggcaga agattctaca gaactctttg aaactgacta cttcggaacg
    46441 ccagcctact tgagccaatc aggtcaactt tacctagaag caggggctat ggctcttggt
    46501 cgtgtctttg actttggtcc agttttccgt gctgaaaaat caaaaacacg ccgtcacttg
    46561 actgagttct ggatgatgga tgctgagtac tcatacttga cacatgatga gtcgcttgac
    46621 ttgcaagaag cttatgtgaa agctcttcta caaggtgttc ttgaccgcgc gcctcaagcc
    46681 ttggaaacct tggaacgtga tacagaactc ttgaaacgct acattgcaga gccattcaaa
    46741 cgtatcactt acgatcaagc cattgacctc ttgcaagagc atgaaaatga tgaagatgct
    46801 gactacgagc atcttgagca tggtgatgac tttgggtcac cacacgaaac ttggatttca
    46861 aaccactttg gtgtgccaac atttgtcatg aactatccag cagccatcaa ggctttctac
    46921 atgaaaccag ttcctggaaa tccagagcgc gtgctttgtg cagacttgct tgctccagaa
    46981 ggctatggag aaattatcgg tgggtctatg cgtgaggaag attacgatgc ccttgtcgct
    47041 aagatggatg aacttggcat ggatcgtaca gaatatgaat tctaccttga ccttcgtaaa
    47101 tacggtacag ttccacacgg aggatttggt atcggtatcg aacgtatggt aaccttcgca
    47161 gcaggaacaa aacatatccg tgaagctatt ccattcccac gtatgttgca ccgtatcaaa
    47221 ccataagaac aggaaaacgc ccatgtggcg ttttttcgaa ttctagtgtt tttacttgcg
    47281 taaaaaaatt ttttctagta taatagttta ttgtgagcga acctcactta ccccttgcaa
    47341 agtcttgggg tcattagacc aaaaggagga acatatcaat ggctaaatac gaaattcttt
    47401 atatcattcg tccaaacatt gaagaagaag ctaaaaacgc tttggtagca cgttttgact
    47461 ctattttgac tgacaacggt gcaactgttg ttgaatcaaa aacttgggaa aaacgtcgtc
    47521 ttgcatacga aatccaagat ttccgtgaag gactttacca catcgttaac gttgaagcaa
    47581 atgacgatgc agctcttaaa gagtttgacc gtctttcaaa aatcaacgct gacattcttc
    47641 gtcacatgat cgtcaaaatt gacgcgtaag aaggtaaact atgattaaca atgttgtact
    47701 tgtagggcgt atgacacgtg acgctgagtt gcgttatacc ccatcaaatg tagcagttgc
    47761 gacttttact cttgcagtaa accgtacatt taagagtcaa aatggtgaac gtgaggctga
    47821 ttttatcaat gtcgttatgt ggcgccaaca ggctgaaaat cttgctaact gggctaaaaa
    47881 aggctcactt atcggggtga caggtcgtat ccagactcgt agttacgata accagcaagg
    47941 acaacgtgtc tacgtgacag aggtcgtggc tgagaatttc caaatgttgg aaagccgtag
    48001 tgtgcgtgag ggtcacacag gtggagctta ctctgcacca actgcaaact attcagcacc
    48061 tacaaattca gtaccagact tttcacgtaa tgaaaatcca tttggagcaa caaacccatt
    48121 ggatatttca gatgatgatt taccattcta atggacaact aaacttataa aggagaaaaa
    48181 acatggctca acaacgtcgt ggcggattca aacgccgtaa aaaagttgat tacatcgcag
    48241 caaacaaaat tgaatatgtt gattacaaag atactgagct tcttagccgt ttcgtttcag
    48301 aacgtgggaa aatccttcct cgtcgtgtaa caggaacttc agctaaaaac caacgtaaag
    48361 taacaacagc tatcaaacgc gctcgcgtaa tggctttgat gcctttcgta aacgaagatt
    48421 aaagaaaaga cccggttggg tctctttttc atgagcttga aaacaagaaa gcgaattaag
    48481 accccaacgg gtcttttttc acaagctttg aaatgagaga gcgagttagg ctcagtggct
    48541 tcctttttac gagtttgaaa acaagagaac acattaaaag cacgatggag ctttttcata
    48601 aatatgtctc ttttctcatc caagaaatta aaataaaaat gataaacttt ttgaaaatag
    48661 gggatttgcc tactttatga tataatggaa agagttagat tgaaagaggt agtgagatgg
    48721 acgcgaaatt aagatacaag gcaaagaaga tcaagattgt cttttttgat attgatgata
    48781 cattgcggaa ttcaaagaca gggtttattc caactacaat tcccactgtt tttaaacagt
    48841 tgcgtgaaaa aggaatttta acaggaatcg cctctggacg tggcattttt ggtgttgttc
    48901 cagagattcg tgatctcaag cctgactttt ttgtaacttt gaatggggct tatatcgaag
    48961 ataaaaaagg tcaggtcatt tatcagcatc agattgaaaa gtcagatgtt gaggagtata
    49021 tctcttgggc taagcaagaa ggaattgagt atggcttggt tgggagtcat gatgccaagt
    49081 tgtcgactcg caccgatatg atgagtgaag ctatcaatcc aatttatccc gacttagatg
    49141 tagatcccga tttccatgaa aaagaagata tctatcagat gtggactttt gaagataagg
    49201 gagatgactt gcacttgcct gacagtctct cagacaaact tcgcatggtt cgttggcatc
    49261 aacattcgtc tgatattgtg ccgatttcag gctccaaagc gacgggggtg gaaaaggttg
    49321 tggaacacct tggcttgaaa ccagagaagg tcatggtttt tggagatggt ctcaatgact
    49381 tggaactctt tgattatgct ggaatcagcg ttgccatggg aatttctcat gataaaatca
    49441 aagaaaaagc agattatatt acaaaaacat tagaagaaga tggcattttt gatgccttag
    49501 aagtatttgg tatggtagaa aaagaattgc attttccaca agtagacatt gaaacagtag
    49561 aaggtcttct tgcgactatt aagaccaatc acggagactt acgtatcaag cttttccctg
    49621 aacatgctcc taaaacagtg gctaactttg tatctctttc aaaagatggc tactatgatg
    49681 gtgtcatttt ccaccgtatt atcaaggact ttatgatcca aggtggagac ccaactggaa
    49741 ctggtatggg tggcgagtca atctacggcg aatcttttga ggatgaattc tcagaagagc
    49801 tttacaatat ccgtggtgct ctttccatgg caaatgctgg tccaaatacc aacggcagcc
    49861 agttctttat cgtgcaaaac caacacctac cttattcgaa gaaagaaatt actcgtggtg
    49921 gttggccaga accgattgca gaaatctatg ccaatcaagg tgggacacct cacctagacc
    49981 gccgtcacac ggtttttggt cagttagctg atgaagcatc ttacgctgtc ttggatgcca
    50041 ttgctgctgt tgagacagga gctatggaca agccagttga agatgttgta attgaaacta
    50101 ttgaaatcga ggactaagat gaaaatcggt gataagctaa aggggcgtat tacagggatt
    50161 cagccctacg gtgcctttgt tgagttagag acgggtgata cggggctgat tcacatttca
    50221 gaaattcgga caggatttat tgaaaatatt catgaaacct tgaaagtcga tgaagaggtt
    50281 caagttcagg tactggattt agatgaattt acggggaaag ccagtctttc tatccgcact
    50341 ttggaggaag aaaagtacca gtttcctaga cggagacgct tttcaagtga ccgctttaac
    50401 tacggttttg ctccctttcg acgaatgcta ccaatctgga ctggagaagc tctgcaccat
    50461 ttaaaaaaga agaagtagtt tagagtttta tattttttgt aatgttaata taaatttatt
    50521 ataataggac catggaagaa gaacaattat taaaatcagg agagcgcatt aaccagctct
    50581 tttcgacaga tatcaaaatc attcaaaata gagaggtttt tagctattcg gtggatagtg
    50641 ttctcttatc acgatttcca cgttttccta agaaggggtt gattgtggat ttctgtgctg
    50701 ggaatggagc agtggggctt tttgctagca ctcgtactca agcacagata ttgtctgttg
    50761 agattcagga gcgtttggcg gatatggctg aacgctctgt ccgtttgaat ggattagagg
    50821 agcaaatgca ggtcatctgc gatgatttga aaaatatgcc tgctcacatt caggggagta
    50881 aggtagatat gattttgtgt aatccaccct atttcaaggt ggatccttat tctaatctga
    50941 acgagagtga acattatctc ttggctcgac acgaaatcac gactaatttg gaagaaatct
    51001 gtcgtagtgc ccagagtatt ctcaagtcta atgggcgttt ggccatggtt catcgtcctg
    51061 atcgacttct ggatattttg gatacgttaa aacgacataa tctagcccct aagcgcctgc
    51121 agtttgttta tccaaaaaga gaaaaggaag ccaatatgct tttgattgag gcgatcaagg
    51181 atggctcaac aagtggcttt aaggtcttac ctcctttgat tgtccacaat gatgatggct
    51241 cttatacgcc cgaaatcgaa gagatttatt atggatcata aggcttatat gtacgttctg
    51301 gagtgtcgtg atggatccta ctatataggc tatacgactg atgtgagaag acgcctcgct
    51361 atccacaata gtgggaaggg agccaaatat acacgagcac gcttgccagt caaacttatc
    51421 tatgctcaag gttttgccag taaggaagaa gccatgtcgg ctgaagctct tctcaagcgt
    51481 aagaagaggc cacagaagga agaattttta tctgaaaatc aagatagaaa tttactcagt
    51541 tattttgaag aatcgtgggg agtcctttga ctcctcttac ctttgtcaaa aagcgaaaaa
    51601 aatgctacaa taaagaaaat aaacaaaatg aggtattatc atgtccaaga ttctagtatt
    51661 tggtcaccaa aatccagact cagatgccat cgggtcatct gtagcttttg cctaccttgc
    51721 aaaagaagct tacggtttgg atacggaagc tgttgccctt ggaactccaa atgaagaaac
    51781 agcctttgtc ttgaactatt ttggtgtgga agcaccacgt gttatcactt ctgccaaagc
    51841 agagggggca gagcaagtta tcttgactga ccacaatgaa ttccaacaat ctgtatcaga
    51901 tatcgctgaa gtagaagttt acggtgttgt agaccaccac cgtgtggcta actttgaaac
    51961 tgcaagccca ctttacatgc gtttggagcc agttggatca gcgtcttcaa tcgtttaccg
    52021 tatgttcaaa gaacatggtg tagctgtgcc taaagagatt gcaggtttga tgctttcagg
    52081 tttgatttca gatacccttc ttttgaaatc accaacaaca cacccaacag ataaaatcat
    52141 tgctcctgaa ttggctgaat tggctggtgt gaacttggaa gaatatggtt tggcaatgtt
    52201 gaaagctggt accaacttgg ctagcaaatc tgctgaagaa ttgattgata tcgatgctaa
    52261 gacttttgaa ctcaacggaa ataatgtccg tgttgcccaa gtgaacacag ttgacatcgc
    52321 tgaagttttg gaacgccaag cagaaattga agctgcaatg caagctgcaa acgaatcaaa
    52381 cggctactct gactttgtct tgatgattac agatatcgtc aactcaaact cagaaatctt
    52441 ggctcttggt gccaatatgg acaaggtcga agcggctttc aacttcaaac ttgaaaacaa
    52501 tcatgccttc cttgctggtg ccgtttcacg taagaaacaa gtggtacctc aattgactga
    52561 aagctttaat gcgtaagatt ttgggtgtca gctcaaaatc ggaaagtcta gtttgcctta
    52621 tatcgaaagg agtttcggct ccttttttct aggagtgaag tatgttagaa aatggcgatt
    52681 tgatttttgt gagagatggg tcagacatgg gacaggccat ccagacttcc acaggtaact
    52741 atagccatgt tgccatttat ttggatggga tgatttatca tgctagtgga caggctggtg
    52801 ttgtctgtca agaaccggca gacttctttg agtccaatca tttgtacgac ctctatgttt
    52861 acccagaaat ggatatccag tcggtgaagg aaagagcttg cagacatctt ggagcaccct
    52921 acaatgcttc tttctatcca gatgcagctg gtttctactg ctcccagtat atagcagaaa
    52981 tcctacctat ttttgaaact attcctatga aatttggaga tggggaacag gagattagtg
    53041 atttttggag ggagtattac atagaactag gtctgcctgt tcctctgaac caagctggga
    53101 ccaatcctag tcagttggca gcatcgcctc tgttacaatg taaagaaagg aatcttcatg
    53161 attcagattt ttaatccatc tcgtttgacg agacagccat ttttggagaa ttgatccgct
    53221 atctggacca gtatgaggat gtgattctac gggaaattaa ggctcaattt ccagatgttg
    53281 cagttgataa actcatggaa gagtatataa aggcaagctt gattctacgt gaaaataagc
    53341 gctattacct caattttcct acgcttgaat cacttgatag tcttgaactg gatcaagaga
    53401 tttttgtcag agaagctagt ccggtctatc aagccttgtt ggagcagagt tttgagacgg
    53461 aattgcgcaa tcaaatcaat gcagctattt tagttgaaag acggactttg cgcgcattaa
    53521 aatgaccctg tccaattatt tttacaaggt caaacagcag tatcctttga cagaaaaaca
    53581 gcaggagctc tatgacattt taggagatgt taatcctgag tatgcactca agtatatgac
    53641 ggcttttttg ttgaaatttc tcaaaaaaga ccagcttatg cagaaatgcc gtgatatctt
    53701 tgtggacagt ttggttgtct taggctatat tgtgcaaaat gaagatagaa agtatgagtt
    53761 ggctatcgat tttgataagg agagattaac tttctactta gcgtgatttc ttgtttctga
    53821 gcacattgtt tgactttcct tagtattcgg tataaactat atgtaaccgg taacacatat
    53881 cggaataaac taaaggagac aatcatatgt cacttgaaaa caaattggaa caagcaacag
    53941 gcgctgtcaa agaaggtttt ggtaaagtta ctggagacag caagacagaa cttgaaggag
    54001 ctgttgaaaa aacagttgct aaggcaaaag acgttgtaga agacgcaaaa ggtgctgtag
    54061 aaggtgccgt tgaaggtttg aaaaacgttt ttactaaata ataggaaaaa atcaagggtt
    54121 tcattttccc ttgatttttt ctattcttat aaataatttt ctgcgacggc tgtatctcct
    54181 gggtaggatt ctttcttgcc ctggatgatt tggtaacaat cggctccctt acccgcaata
    54241 ataactgcat ctaattcgtg atttgtgata gccattgccg ccttgatggc ttcttggcga
    54301 tccgcaatct tttcaacagg atgattgatg tagctactaa tttcatctgc aatggccatt
    54361 gggtcttcat agttagggtc atcagcagtc agaaagactt gaatctcagg gtgttgattg
    54421 aggaggaggc caaagtcctt acgacgactt tctcccttgt ttcctgttga tcccagaacc
    54481 agagcaatct ttccggtttg atgagtttca accacattga tgagtttttt cagactatcc
    54541 ccattgtggg catagtcgat gaagaccttg gctccatttt tctgagtgag gacttccata
    54601 cgaccaggaa cgcgggttgc agcgatgcct tttttgatgt cctcaagact tgctccgaga
    54661 cggagacaag caagtccagc agcaactgca ttttcttggt tgaagttgcc aatgagttgg
    54721 atatcataat ctccagcgag tttacccgta gctgaaaagc taaaggcttt ggaattctcg
    54781 atttggttat caaattggct accatagaaa tcatggtctt gatcttcaac ctgttctttc
    54841 aagactgaga agtggtccat gtcactgtta atgatgactg ctcggctatt ttccatcaag
    54901 agacgcttgt ggtagaaata gtcttcaaag ctagagtgtt caatcgggcc gatatggtca
    54961 ggagtgatgt taagaaagac tcctacatca aaggtcagtc catagactcg atggactaga
    55021 taggcttgac tggagacttc catgatgagg tgggtacggt cattttgcac agcctgattc
    55081 atcatgtcaa agaggtcaat actctcaggg gttgtcaacg ctgacttaaa aaaagtctcg
    55141 ccatcaagag ttgtgttcat ggtcgacaac atagcaggtc tatgcccttg agataagatg
    55201 ttataggcga aataggttgc tgttgtctta cccttagtac cagtaaaggc aaggagtttg
    55261 agtttctctt gtggattacc atagaactcc atggcaatca aactcatggc tttctttata
    55321 tcgttcacaa tgatgacagg gatatcgact tcgtagtcct tttcagctac ataccaagct
    55381 aaaccttgtg ttatagcaga aagaaggtat tcttttttaa aggcagcgcc ttttgcaaaa
    55441 aaaagagtgt cttctgttac ttttcggctg tcgtagctga tgctatcaaa aataactttg
    55501 ctgtagttgt agtggtaatg accttggtca ataatttcgc gaaaaaggcc atctttcttt
    55561 aaaatatcta atacggtttc aatcttaatc atactttcta ttgtaaaccg aaagtcgtaa
    55621 atttacaagt aacaaggaaa agtttataat ggaagataag gagtttttcc tagttatcaa
    55681 aattgaatga ggaatctatg tcgcacgaaa acaatcacca gcaggcccag atgttacggg
    55741 ggactgcttg gctaacggct agtaacttta tcagtcgcct actcggggct gtttacatta
    55801 tcccttggta catctggatg ggggcttatg cagctaaggc aaatggtctc tttaccatgg
    55861 gttacaatat ctatgcttgg ttcttgttgg tttcaacagc ggggattcca gttgcggtgg
    55921 ccaagcaagt tgccaagtat aataccatgc gagaagaaga gcatagcttt gccctgattc
    55981 ggagcttctt aggctttatg acaggactag gtctggtttt tgctttagtc ttgtatgtct
    56041 ttgctccttg gctagcagac ttgtctggcg tgggcaaaga cttgatccca atcatgcaaa
    56101 gcttggcttg gggagtcttg attttcccgt ctatgagtgt tatccgagga tttttccaag
    56161 ggatgaataa cctcaaaccc tatgctatga gccaaattgc tgagcaggtc attcgtgtta
    56221 tctggatgct cctagcaacc tttatcatta tgaagctcgg ttcaggagat tatctagcag
    56281 ccgttaccca atcaaccttt gctgcctttg tcggtatggt agccagtttt gcagtcttga
    56341 tttatttcct tgcccaagaa ggttcactca aaagagtctt tgaaacagga gataagatta
    56401 acagtaagcg tctcttggtt gataccatta aggaagccat tccttttatc ctgacagggt
    56461 ctgccatcca gctcttccag attttggatc agctgacctt tatcaatagt atgagctggt
    56521 ttaccaacta cagcaatgag gacttggttg tcatgttttc ttatttctca gccaatccta
    56581 ataaaatcac gatgattttg atttctgtag gggtttcgat tgggagtgtt ggtttgccac
    56641 ttttgacgga aaactatgtc aagggggact tgaaagcagc ttctcgtctc gttcaggaca
    56701 gtctcaccct actctttatg ttcttgctac cagcaacggt tggagtggtt atggtaggag
    56761 aacctcttta tacggtcttc tatggtaagc cagatagttt ggctctggtc ttatttgtct
    56821 ttgcagtttt gcagtctatt attttaggct tgtacatggt cttgtctcca atgcttcagg
    56881 ccatgttccg caaccgcaag gccgttctct attttatcta tggttctatt gccaagctag
    56941 tcttgcaact acctaccatc gccctcttcc acagttatgg tcctttgatt tcaacaacca
    57001 ttgctctcat cattcctaac gtcttgatgt atcgggatat ttgtaaagta actggtgtca
    57061 agcgcaaggt gattttgaag cgaaccattt taatcagttt gctgacccta gtcatgtttc
    57121 tgttaatagg aaccatccag tggctgttag gatttttctt ccaaccaagt ggacgtttgt
    57181 ggagcttctt ttatgtagct cttgtcggtg ccatgggggg tggactttat atggttatga
    57241 gtctgcgtac ctatttatta gataaggtaa taggaaaagc ccaagcagat cgcctgcgag
    57301 caaaatttaa gctttcgtaa ggtagcattt ataaataaaa ggaataagtt gaacaatctt
    57361 ttaggagaac ttgaaactta ttcctttttt agcgtcaaaa tagctaaaat tatctttcaa
    57421 aaatagaaaa tgaggttttt ttgatttttt ggaaaaaaca attgactaaa caaacccaga
    57481 gttgtataat aaaacaaata tttaaagcag gaggttctgg aaatgaaaaa gtctaagagc
    57541 aaatatctaa ccttggcagg tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga
    57601 aattctagca ctgcatcaaa aacctataac tatgtttatt caagtgatcc atctagtttg
    57661 aactatctag cagaaaaccg cgcagcaaca tccgatattg ttgcaaattt ggtagacggg
    57721 ttattagaaa atgaccaata tgggaatatt attccatcat tagcagagga ttggactgtt
    57781 tctcaggacg gtttgaccta tacctacaaa cttcgtaagg atgccaagtg gtttacttct
    57841 gagggagaag aatatgcgcc tgtaactgcc caggattttg tgacaggttt gcaatatgca
    57901 gctgataaaa aatcagaagc tttgtatcta gtgcaggact ctgttgctgg tttggatgac
    57961 tatatcactg gtaaaacaag cgacttttca actgtcggtg tcaaggcact tgatgaccaa
    58021 acggttcaat atactttggt taaaccagaa ctttactgga attcaaaaac acttgcaacg
    58081 atactttttc ctgttaatgc agatttcctg aaatcaaaag gggatgattt tgggaaggcg
    58141 gatccatcta gtattttgta caatggacct ttcttgatga aagcacttgt ctcaaaatct
    58201 gctattgaat ataagaaaaa ccctaattac tgggatgcta agaatgtctt tgtagacgat
    58261 gtgaaattga cctactatga tggtagcgac caagaatcac tggaacgtaa ttttacagct
    58321 ggtgcttata ctacggctcg tctttttcct aacagctcca gctatgaagg gattaaagaa
    58381 aaatacaaaa acaatatcat atatagtatg caaaattcaa cttcatattt ctttaatttt
    58441 aacctagata ggaagtctta caattatact tctaaaacaa gtgacattga aaagaaatcg
    58501 actcaggaag cagttctcaa taaaaacttc cgtcaggcta tcaattttgc ttttgacaga
    58561 acatcttatg gggctcagtc tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta
    58621 gtggttcctc caaactttgt cagtatcaag ggaaaagact ttggtgaagt tgtagtctct
    58681 aagatggtca actatggtaa ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct
    58741 tactacaatc ctgagaaagc caaggctaag tttgcggaag ctaagaaaga actcgaagca
    58801 aagggtgttc aattcccaat ccacttggat aagactgtgg aagtaacaga taaagtaggc
    58861 atacaaggag ttagttctat caaacaatca attgaatctg ttttaggttc tgataatgta
    58921 gtgattgaca ttcagcaatt aacatcagat gagtttgaca gttcaggcta ctttgctcaa
    58981 acagctgctc agaaagacta tgatttatat catggcggtt ggggacctga ttatcaagac
    59041 ccgtcaacct atctcgatat ttttaatact aatagtggag gagttctaca aaatcttgga
    59101 ctagagcctg gagaagccaa tgacaaggct aaggaagttg gactggatgt ctatactcaa
    59161 atgttggaag aagctaataa agagcaagat ccagccaaac gttatgagaa atatgctgat
    59221 attcaagctt ggttgattga tagttcttta gttcttccaa gtgtttcgcg tgggggaaca
    59281 ccatcattga gaagaaccgt accatttgct gctgcctatg gtttaaccgg tacaaaaggg
    59341 attgaatcat ataaatacct caaagtacaa gataagattg tcacaacaga cgaatatgca
    59401 aaagctagag aaaaatggtt gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa
    59461 ttggcaaaac atgtcaaata aaatctaatt gtagataagt ttgtgtaaga agtctttgtg
    59521 cttaaaaacg cataatatca ggtatataaa atcctagatg ttatgcgttt tgttatagga
    59581 agatttatta gattttatcc tcaaattgag ttattcccga ctttatccgt tgaaatatta
    59641 taaggagtat ttatgaaatt aaaattatta agagtagata ctaaggtgat tatggggagt
    59701 ttcttacttg ttctgtctag tctacttgct ttgttgcttc cccttatctt aaagggttta
    59761 atagatggga gttctattga aaatataggt tccaaagtat ttcaatcgtt tttgattttt
    59821 attggtcaag ccttgttttc ttctattggt tactatctgt ttagtcaatc gggtgaaaaa
    59881 aagatagcaa aaatcaggaa aaaagtgata gaggggttga tttatgcaga gaaatccttc
    59941 tttgataaga gccaaagtgg ggagttgact tctgccattg tcaatgacac gagtgtcatt
    60001 cgtgagtttt taattacgac tttcccaaat attattctga gtttagttat ggtacttggt
    60061 tccattgtag tcttatttag tcttgattgg aatctttctc tacttttatt catcactctt
    60121 ccttgtatga tgtttattat cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt
    60181 ttacaggagg aaatcggatt tttaacaggg taattgactg aaaagattca agaacatgaa
    60241 ttaattaaga ctaaccaagc agagaaaagt gtacaggatg ttttggataa ttgtattgaa
    60301 agggtacaaa acaattcact gaaatcagat agggttactt cttttgagac cccgtttgct
    60361 ctcttattta tctttgcgac tatagctgtg atgctaacct atgggggtta tcgggtcagc
    60421 gcaggatata tatctgtggg aaccttggtt tcgtttttga tttacctctt tcaattactt
    60481 aatcctatta gtaatatagc taattttgta actgtttatt ctaggagcaa gggatcttca
    60541 gttgcactgg agaacttgct tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta
    60601 tcaggacaag ggttgaattt
//
LOCUS       DAVBOM010000006        59147 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBOM010000006 DAVBOM010000000
VERSION     DAVBOM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59147
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.006"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..190
                     /locus_tag="VQ878_000339"
     CDS             <1..190
                     /locus_tag="VQ878_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3094752.1"
                     /translation="HTRDEPIEQVLKEIRKRGFKNKAFRTLEDVMNQLQDVIQGLEKE
                     VIKSIVNRRWTRMLFESR"
     gene            complement(307..654)
                     /locus_tag="VQ878_000340"
     CDS             complement(307..654)
                     /locus_tag="VQ878_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3094753.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(765..2540)
                     /gene="spxB"
                     /locus_tag="VQ878_000341"
     CDS             complement(765..2540)
                     /gene="spxB"
                     /locus_tag="VQ878_000341"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET3094754.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2747..4990)
                     /locus_tag="VQ878_000342"
     CDS             complement(2747..4990)
                     /locus_tag="VQ878_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3094755.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSHAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5000..5371)
                     /locus_tag="VQ878_000343"
     CDS             complement(5000..5371)
                     /locus_tag="VQ878_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET3094756.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5382..5777)
                     /locus_tag="VQ878_000344"
     CDS             complement(5382..5777)
                     /locus_tag="VQ878_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET3094757.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5961..6059
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6143..6934
                     /gene="thiD"
                     /locus_tag="VQ878_000345"
     CDS             6143..6934
                     /gene="thiD"
                     /locus_tag="VQ878_000345"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3094758.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7143..7775)
                     /locus_tag="VQ878_000346"
     CDS             complement(7143..7775)
                     /locus_tag="VQ878_000346"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3094759.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7768..8571)
                     /locus_tag="VQ878_000347"
     CDS             complement(7768..8571)
                     /locus_tag="VQ878_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3094760.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8571..9095)
                     /gene="thiW"
                     /locus_tag="VQ878_000348"
     CDS             complement(8571..9095)
                     /gene="thiW"
                     /locus_tag="VQ878_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET3094761.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9100..9792)
                     /gene="tenA"
                     /locus_tag="VQ878_000349"
     CDS             complement(9100..9792)
                     /gene="tenA"
                     /locus_tag="VQ878_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET3094762.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9803..10453)
                     /locus_tag="VQ878_000350"
     CDS             complement(9803..10453)
                     /locus_tag="VQ878_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET3094763.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10455..11840)
                     /locus_tag="VQ878_000351"
     CDS             complement(10455..11840)
                     /locus_tag="VQ878_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094764.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11841..12401)
                     /locus_tag="VQ878_000352"
     CDS             complement(11841..12401)
                     /locus_tag="VQ878_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3094765.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12663..12751)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12960..13589)
                     /locus_tag="VQ878_000353"
     CDS             complement(12960..13589)
                     /locus_tag="VQ878_000353"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3094766.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13591..14373)
                     /gene="thiM"
                     /locus_tag="VQ878_000354"
     CDS             complement(13591..14373)
                     /gene="thiM"
                     /locus_tag="VQ878_000354"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3094767.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(14784..15323)
                     /locus_tag="VQ878_000355"
     CDS             complement(14784..15323)
                     /locus_tag="VQ878_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET3094768.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENNYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAE"
     regulatory      complement(15538..15626)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15880..17016)
                     /gene="lctO"
                     /locus_tag="VQ878_000356"
     CDS             complement(15880..17016)
                     /gene="lctO"
                     /locus_tag="VQ878_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET3094769.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17641..19131)
                     /gene="lysS"
                     /locus_tag="VQ878_000357"
     CDS             complement(17641..19131)
                     /gene="lysS"
                     /locus_tag="VQ878_000357"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET3094770.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19259..19405)
                     /locus_tag="VQ878_000358"
     CDS             complement(19259..19405)
                     /locus_tag="VQ878_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET3094771.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            19632..20300
                     /locus_tag="VQ878_000359"
     CDS             19632..20300
                     /locus_tag="VQ878_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3094772.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPLIGIVLSSEVCATLGLVFLGSSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTCHAGFGNPST
                     LSRK"
     gene            20260..20640
                     /locus_tag="VQ878_000360"
     CDS             20260..20640
                     /locus_tag="VQ878_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET3094773.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            20650..20937
                     /locus_tag="VQ878_000361"
     CDS             20650..20937
                     /locus_tag="VQ878_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3094774.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            20938..21706
                     /locus_tag="VQ878_000362"
                     /pseudo
     CDS             20938..21706
                     /locus_tag="VQ878_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21718..22584
                     /locus_tag="VQ878_000363"
     CDS             21718..22584
                     /locus_tag="VQ878_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3094775.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(22671..23318)
                     /locus_tag="VQ878_000364"
     CDS             complement(22671..23318)
                     /locus_tag="VQ878_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094776.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23315..24013)
                     /locus_tag="VQ878_000365"
     CDS             complement(23315..24013)
                     /locus_tag="VQ878_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094777.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(24023..24775)
                     /locus_tag="VQ878_000366"
     CDS             complement(24023..24775)
                     /locus_tag="VQ878_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094778.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24775..25539)
                     /locus_tag="VQ878_000367"
     CDS             complement(24775..25539)
                     /locus_tag="VQ878_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094779.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25635..26038)
                     /locus_tag="VQ878_000368"
                     /pseudo
     CDS             complement(25635..26038)
                     /locus_tag="VQ878_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26218..26850)
                     /locus_tag="VQ878_000369"
     CDS             complement(26218..26850)
                     /locus_tag="VQ878_000369"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET3094780.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26884..27585)
                     /gene="pyrF"
                     /locus_tag="VQ878_000370"
     CDS             complement(26884..27585)
                     /gene="pyrF"
                     /locus_tag="VQ878_000370"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET3094781.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27818..29017)
                     /gene="divIB"
                     /locus_tag="VQ878_000371"
     CDS             complement(27818..29017)
                     /gene="divIB"
                     /locus_tag="VQ878_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET3094782.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29027..30085)
                     /locus_tag="VQ878_000372"
     CDS             complement(29027..30085)
                     /locus_tag="VQ878_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET3094783.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30087..31439)
                     /locus_tag="VQ878_000373"
     CDS             complement(30087..31439)
                     /locus_tag="VQ878_000373"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET3094784.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(31543..32184)
                     /locus_tag="VQ878_000374"
     CDS             complement(31543..32184)
                     /locus_tag="VQ878_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094785.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32186..34206)
                     /locus_tag="VQ878_000375"
                     /pseudo
     CDS             complement(32186..34206)
                     /locus_tag="VQ878_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(34277..34576)
                     /locus_tag="VQ878_000376"
     CDS             complement(34277..34576)
                     /locus_tag="VQ878_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3094786.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(34942..35196)
                     /locus_tag="VQ878_000377"
     CDS             complement(34942..35196)
                     /locus_tag="VQ878_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET3094787.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35216..37057)
                     /gene="typA"
                     /locus_tag="VQ878_000378"
     CDS             complement(35216..37057)
                     /gene="typA"
                     /locus_tag="VQ878_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET3094788.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37219..37944
                     /locus_tag="VQ878_000379"
     CDS             37219..37944
                     /locus_tag="VQ878_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3094789.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(37984..38211)
                     /locus_tag="VQ878_000380"
     CDS             complement(37984..38211)
                     /locus_tag="VQ878_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094790.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38300..38680)
                     /locus_tag="VQ878_000381"
     CDS             complement(38300..38680)
                     /locus_tag="VQ878_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3094791.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(38680..38949)
                     /locus_tag="VQ878_000382"
     CDS             complement(38680..38949)
                     /locus_tag="VQ878_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET3094792.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39013..39921
                     /locus_tag="VQ878_000383"
     CDS             39013..39921
                     /locus_tag="VQ878_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3094793.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(39975..40730)
                     /locus_tag="VQ878_000384"
     CDS             complement(39975..40730)
                     /locus_tag="VQ878_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3094794.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40751..41680)
                     /locus_tag="VQ878_000385"
     CDS             complement(40751..41680)
                     /locus_tag="VQ878_000385"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET3094795.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(41695..42318)
                     /locus_tag="VQ878_000386"
     CDS             complement(41695..42318)
                     /locus_tag="VQ878_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET3094796.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42311..43549)
                     /gene="hflX"
                     /locus_tag="VQ878_000387"
     CDS             complement(42311..43549)
                     /gene="hflX"
                     /locus_tag="VQ878_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET3094797.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(43542..44426)
                     /gene="miaA"
                     /locus_tag="VQ878_000388"
     CDS             complement(43542..44426)
                     /gene="miaA"
                     /locus_tag="VQ878_000388"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET3094798.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            44547..44717
                     /locus_tag="VQ878_000389"
     CDS             44547..44717
                     /locus_tag="VQ878_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET3094799.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(44765..45604)
                     /locus_tag="VQ878_000390"
     CDS             complement(44765..45604)
                     /locus_tag="VQ878_000390"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET3094800.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45701..46660)
                     /locus_tag="VQ878_000391"
     CDS             complement(45701..46660)
                     /locus_tag="VQ878_000391"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET3094801.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(46787..47784)
                     /locus_tag="VQ878_000392"
                     /pseudo
     CDS             complement(46787..47784)
                     /locus_tag="VQ878_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(47834..48451)
                     /locus_tag="VQ878_000393"
     CDS             complement(47834..48451)
                     /locus_tag="VQ878_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3094802.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48452..50173)
                     /gene="pabB"
                     /locus_tag="VQ878_000394"
     CDS             complement(48452..50173)
                     /gene="pabB"
                     /locus_tag="VQ878_000394"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET3094803.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50234..55876)
                     /locus_tag="VQ878_000395"
     CDS             complement(50234..55876)
                     /locus_tag="VQ878_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3094804.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTET
                     TEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRG
                     TKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKT
                     EDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAA
                     IKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLK
                     EEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNL
                     LAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFE
                     ELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPL
                     FDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGF
                     VNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASM
                     LVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAK
                     VIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADA
                     KVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNK
                     DFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSS
                     SDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTG
                     SNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAA
                     LLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTY
                     DAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIK
                     AAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQ
                     IEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDY
                     APLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTH
                     VNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWY
                     ITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTV
                     GSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGI
                     KMMNSIYAGNTSEGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFG
                     DQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKA
                     LEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK"
     gene            complement(55898..56461)
                     /locus_tag="VQ878_000396"
     CDS             complement(55898..56461)
                     /locus_tag="VQ878_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET3094805.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(56577..58268)
                     /locus_tag="VQ878_000397"
     CDS             complement(56577..58268)
                     /locus_tag="VQ878_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3094806.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58265..59002)
                     /locus_tag="VQ878_000398"
     CDS             complement(58265..59002)
                     /locus_tag="VQ878_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3094807.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        17514 a        12985 c        10677 g        17971 t
ORIGIN      
        1 acacaccaga gatgaaccca ttgaacaagt gttgaaagag attcgtaaac gtggatttaa
       61 gaataaagcc tttcgaactt tggaagatgt catgaatcaa cttcaagatg tcatacaagg
      121 actggagaag gaggtgataa agtccatcgt taatcggaga tggactagaa tgctttttga
      181 aagcagatga gtattatatg caatttcttt atataaaaag accggattgc tccgatcttt
      241 caatagttca tattctcaat ttctatttta aaaatagcta aggttaacgt caaatgacta
      301 cgcgacctat ttcatacgat aaaaatcaag cactagacca gcaggtcctt gaactaataa
      361 ggactctgtt ccccaatcgg ttacagttgg tccgtgtaaa acctttatac caagctcgtt
      421 caaccgtttg tagttctggt ctacatcctc aacctcgata tgaataatga ttcctgactg
      481 aaagttttcc aaaggaacca aatgattttg tgacaacata aggcagtgac taccaatcgt
      541 aaactgagca aaaccatcat cagcataatc tgccttttta tccaagatat gctccaagtc
      601 agcacagact tggggaacat ttgaaacgat aatatctaat tgatttaaat tcatttactc
      661 tcctccataa aaagaccgga ttgctccgat cttttaaagt tctgctctat gaaaatcaaa
      721 gaataaagtc tacaagtttc atatttgatt ttcggcgaga ggaattattt aattgcgcgt
      781 gattgcaatc cttcttcttc caagaagaga cggaatggta cgagttcttc tgcttcgtat
      841 ttttccttga aggctttgat agcttcttct gagtgaagtt ttggatccaa ttcaagtact
      901 tctactggaa gtggacggtg ttgagtgatg cgagcatcga tgacaacagt tttaccttct
      961 ttgttcaatt taacagcttc tgcaacaact gcatcgatgt cttcgatacg gtcaactgtg
     1021 aatccaacag ctccttgagc ttccgcaatt ttagcgtagt cagcgtttgt gaagtctaca
     1081 ccaaacaagt gtttgtttgt atcttcgtat ttgttcttga tgaagccgta ctcagcattt
     1141 gagaagacaa ggttgataac tggaaggtcg tattgaacgt ttgtgataac gtctgggtag
     1201 cacatgttga atgctccgtc acccatgatg ttccatactt ggcgatctgg attgtctttc
     1261 ttagcagcga taccaccagg aagggcaata cccattgtcg caaagagtgg agatgtacgc
     1321 cacatgttct taggtgtcat gtgaaggtga cgagtagatg tttgagtagt gttacctacg
     1381 tcgattgagt agatagcgtc ttgatcagca tgtttgttga ttgcattgta aacttgatac
     1441 aattgcaatt caccctcagt tttaccttcg agtttgttca tgtaatcacg ccagttttga
     1501 ttgttcttaa cgtttgcacg ccaccatgga gttgattcaa ctgggtttac tttgtcaagg
     1561 atagctttag ctgcttgacc agcatcacca aggattgaag cgtcaagggc atgacgttta
     1621 ccaagtttgt aagggtcgat atcgacttgg atgaattttt cagtgttctt gaatgcttcg
     1681 taaacttcag cgaatgggaa gtttgaacca aggaaaagaa ctgtgtctgc ttcaaagacc
     1741 acttcgttgg ctggtttcca accaacacgg taagcagaac ctgtcaaacc ttcatagttc
     1801 cattcgaaag cttcaaagtt tttaccagtt gtgatgattg gtgctttgat tttacgtgac
     1861 aattcagtaa tcacttcacc agctttaaca ccaccaaatc cagcatagat aactgggcgt
     1921 tcagcattgt tcaagatttc aacagctttg tcgatttcaa cttcgttcaa agcaggagcg
     1981 atgaatgagc gttcgtatga acctgaaccg tagtatgagt tttcatcgat ttcttggaaa
     2041 ccgaagttta ctggaatttc aacaacagct ggaccttttt tagaaactgc agcacggcag
     2101 gcttcgtcaa ttacttttgg caattgctca gcgtaagcta cacgtttgtt gtaaacagcg
     2161 ataccgttgt acattgggtt ttggttaagc tcttggaaag catccatgtt caattcgtta
     2221 actggacgtg atccaaggat cgctaggaat ggagtgttat ccatagctgc atcgtaaaca
     2281 ccgttaatca agtgagtcgc acctggacca cctgaaccaa ctgcaacccc gattgagccg
     2341 ccgaatttag cttgcataac cgctgcaaga gcacctgtct cttcgtggcg aacttgtaag
     2401 aaacggatat ctttgtcttc agccaaagca tccatcaatg agctgagtgt tcctgatggg
     2461 ataccgtaga ttgtatctac gccccatgtt ttcaatacgt taagcattgc tgcagatgca
     2521 gtaattttcc cttgagtcat aatgataact ctccttcaat ttttttaaac ttggagaata
     2581 cgattacata gaattggaaa cgttctccaa atttttacta ttccactgta tcatatttat
     2641 gctgactttt ctaaaaatct gctcaaaact ctctattctc tattctaata cagttttgaa
     2701 agtgttgtca tttctgtttt ataacaaaga aatctagtca ttacttttag tctattttac
     2761 taaaatttaa cagaagggaa ctggtcagaa cagatacaga actaaaggcc atggctagac
     2821 ctgccaattc tgggttgaga gccagtccaa cacctgaaaa gactcctgct gcaatcggaa
     2881 ttccgacaac attgtagata aaagcccaga aaagattgag tagaattcga tgaaaggttt
     2941 tcttactcat atcaaaggca cgaaccactc ctaaaagatt attggttgtc aacaccaaat
     3001 ctgctgactc gatggcgata tctgttccag ctcccatagc aatccccaca tctgctacac
     3061 taagggcagg agcgtcattg ataccgtccc caacaaaggc tactttccct gactgttgca
     3121 gtttatggat ttcatgggct ttttcttctg gcaagacgcc tgcaatgacc tcttcaattc
     3181 cgatttgatc tgcaatagca cgcgccacac cagcattgtc tcctgtcagc atgactgttc
     3241 ggagaccacg tttttttagc tgactgatga ctagcttagc attttcctta ggaatatctt
     3301 gcaaagcaag caagcctttg atttcattgt caacagctaa gaacacaact gtcttagctt
     3361 ctttttctag ttcttctagt ttatcttgat aagtattaga aatatccatg ccatccagca
     3421 ttttagcatt tccaagtaaa acttgttttc cattgattcg ccctgaaaca cctttcccgt
     3481 gcaaggcctg aaaattttca acagtttgaa actcaagtcc agcttcactc gctcgcttaa
     3541 cgatagcctc agccagtggg tgttgagaag catcttccaa ggaggctgcc aatccaaaca
     3601 cttctacttc gtcgccgatg atatctgtta ccacaggttt cccttccgtc aaagtcccgg
     3661 tcttatcaaa gacaagagtt tgaactttct ggatttcctg taagacagtt ccatttttga
     3721 ggagaacccc catcttggca ctacgtcctg tccccaccat aagggctgtc ggtgttgcaa
     3781 gtcccaaggc acaaggacag gcgataatca aaaccgccac tccgtagaga agagaggaca
     3841 caaagctagc tccaagcacg accacactat ccctgagcaa gacgaaccaa acccaaaagg
     3901 tcatgattcc taaaatgaca actactggga caaaaatccc tgaaatctta tccgtcaagt
     3961 cctgaatcgg cgcatgactt gtctgagctt tcttcacaaa atccacaatc tgagccaaaa
     4021 cagtctctga gccaactttt tctgctctaa agacaagcgt tccactatga ttgatggttg
     4081 agccaatgac agtatctcca actgtcttgt ccacaggcag actctcacct gtcaccatgg
     4141 attcgtcaat actagagaca ccttctacta cgacaccatc aacagcaatc ttttcaccgg
     4201 gacgcactcg aatcaggtcg cctaccttga cttgttccaa aggaacttgg acataactat
     4261 catcactcaa gacttctgcg gttttagctt gcaagtccag taatttctcc acagcttggg
     4321 acgtattttt tctcattttt tcctcaaaaa ctgctcccaa aagaacgaaa aagaggataa
     4381 atccagcact ttcgaagtaa acagggagac cagcaaagag agcaactagg ctatagaaat
     4441 aagccactag agttcccagc gcaaccaagg tatccatgtt ggcattgtgc tttttaaaac
     4501 tggcccaagc actctggata tatggcttac ctgcaactaa cataataggc gttgttgcta
     4561 gaaaggttcc ccaatgcatg acttgatgac taatgctacc tgtcaacatc ccaatcatga
     4621 gaatcacaag aggcacagta aagatactag taatccaaaa acgttgcagg agagatagag
     4681 attttcgagt cttctcaacg actatatagc ttcccttttg catcttcatg ccacaagaaa
     4741 attcatgtcg ccctaattct tgaggtgtaa aacgaatgac tttctcctca tctacgccga
     4801 ttggttccaa gataccttct tcttcaaaca gaatttcctt ataacagttt gaaggagtag
     4861 cacgatgaaa ggtaatctca gctggaattc ccttttgaag ctggatatgg gctggatgat
     4921 agcctttttc agctcggata cggatttttt gaatgccatt ttctaagctt gctttcacaa
     4981 tttctgtcat agtctccacc tactctacaa tcatcttgcc gtgcatcatg ttcataccac
     5041 aagcaaagcc aaactctcca acctgctcag gcgtgatttc cactacatac tcttccccca
     5101 ttggcaggtt cgcatgtaca ccaaaatctg gaaaaacaat ttgatccaga catggtgaag
     5161 gatccttgcg gtcaaagaca atgcgtgctg gcactgattt cttgaggaca atcaactcag
     5221 gagtatagcc tcccatgact tccactcgaa tctcttggta tccgtttttt tgctgggctt
     5281 tttgtccaga tttttcaggc tttttgaaaa accaaaacaa gataaacgcg ataagggcaa
     5341 tacaaataat ggttacaata ctatttaaca tggcgtctcc tttacataca attacatctt
     5401 acttctgtta cagcacttga tttcttctct gaaatcacag cttccaagtc ttccaagtca
     5461 gtctgagtaa attcacattc tacaatcaag tcagccaaca aattcctaat cctacgggaa
     5521 caaaccttgt ctttgatatc ttggacaagt aaatcccgac tttggtctag agttaaaagc
     5581 gctgaataaa caaaggactt gccttctttt ttccgagtca gacactcttt ctcaaccaaa
     5641 cgagccaaaa gagtttgaat ggtcgacttg gaccagtcga accgctctgc caaaacccta
     5701 atcaaatctg tactggtctg ctccccctgc atccaaataa tcttcatgac ctgccattct
     5761 gcatctgaaa tctgcattac catacctcca aaatctacat ttgtcaatta cactcatcag
     5821 tatactctta aaatctacat ttgtcaatta tagaaataat attttcttcg aaaaatagaa
     5881 ttttaatcat ttgaaaaacg atttgcagtc aaatattact atataaacaa taaaaatatg
     5941 ctatactaaa gaaaaaagaa aacaaccact aggggtgcgt aaagctgaga ttaacgactg
     6001 ttagatccct ctgactcaat ctaggtaatg ctagctgatg gaagtggaaa tgataatggg
     6061 gactagcagt cttctattgc ctttctaaaa cagactagct tgttcttaag aatacaaact
     6121 tcagttggtt gggaggtttt agatgactta tttacccgtt gctttgacca ttgcagggac
     6181 tgaccctagt ggtggtgctg gcattatggc agatttaaag tcattccaag cgagagatgt
     6241 ctatggaatg gctgttgtaa ccagtcttgt cgctcaaaat accagaggtg ttcagctaat
     6301 cgagcacgtt tctcctcaaa tgttgaaagc ccaattggag agtgtctttt ctgatattcc
     6361 acctcaggct gtaaaaactg gaatgttggc tactactgaa atcatggaaa tcatccaacc
     6421 ctatcttaaa aaactggatt gtccctatgt ccttgatcct gttatggttg ctacaagtgg
     6481 agatgccttg attgactcaa gtgctagaga ctatctcaaa acaaacttac tacctctagc
     6541 aactattatt acgccaaatc ttcctgaagc agaagagatt gttggttttt caatccatga
     6601 ccccgaaggc atgcagcgtg ctggtcgcct gattttaaaa gaatttggtc ctcagtctgt
     6661 ggttatcaaa ggcggacatc tcaaaggtgg tgctaaagat ttcctcttta ccaagaatga
     6721 acaatttgtc tgggaaagcc cacgaattca aacctgtcac acccatggta ctggatgtac
     6781 ctttgctgca gtgattactg ctgaactagc caagggcaag agtctttacc aggcagttga
     6841 taaggccaag gcctttatca caaaagctat tcaagatgcc cctcaactcg gtcatggttc
     6901 tggtccagtc aaccatacaa cttttaaaga ttaagaaaaa aactctctag ttcccacttt
     6961 aagggaatta gagagttttt atactcttcg aaaatctctt caaactacgt cagcttccat
     7021 ctgcaacctc aaaacactgt tttgagctga cttcgtcagt cttatctaaa acctcaaggc
     7081 agtactttga gcaacctgcg actagctttc tagtttactc tttgattttc attgagtatt
     7141 aattaggaaa gaatgtcatg caactttgtt aaaaaggctt gcgtttttgc ctcaatatct
     7201 tctgcttgca tcaaatcacg tacaacagct acaccagcta tgccagtgcc cataagctga
     7261 tcaatattct ccgaagtcaa gcctccaata gcaactactg gaatggcaac cgtttggcaa
     7321 attgttttca aggtcgatat cagagtaatg ggcgcatttt ccttggtggt ggttgggaaa
     7381 atggctcctg tacccaagta atctgcacct gatttctccg cttccagagc tcttttaacc
     7441 gttttagcgg tgacaccgag gattttttca ggacccaaga ctttgcgagc taccgaaact
     7501 ggtaattcat catctccgat atgcagacct gctgcatcaa ccgcaagaca aacatccaac
     7561 cgatcatcga ttatcaaggg gacctgatag gcatctgtta tttccttgac ttgttttgcc
     7621 agttgataat attgattggt tgtgagattt ttttctcgca attggactat ggtaacccct
     7681 gaacggcagg ccgtctcaac ttttgcaaga aagctttcca cggaatcttg atagcgattg
     7741 gttaccagat atagtctaag tgcttctcta ttcataaacc tctcctttga tggtatctag
     7801 ccaattttca tctcttctta ggagcgaaag ctgattgagt acttggtaac gaaattcttc
     7861 caatcccatt ccttgaacaa ctattttctc agcagcgata ttgagataag agactgctaa
     7921 gcaagaagct tcaaaaccag tctttccttg gctgagaaaa acggctgtta aggctccaac
     7981 caagtctcct gtccctgtta tccagtctaa ttcagtacag ccattctcca gtacagcaac
     8041 ttgattctcc gaaacaataa ggtccttggg gccagtaact aagaaagaca taccaggata
     8101 ggtctgacac cagtctttca agacttgaag caaatcctcc gtttcttgat ctttagcact
     8161 cgcatcgacc ccaacgccgt ggtgctttaa tccaacaaga cttcgaattt ctgacatgtt
     8221 tcctttaagg accgtaggtc tatagtctaa aaggtcttta actaagctct tacgaatgga
     8281 tgaagtcgtt acgccaaccg catctactac catcgggaga gaagattggt ttgcatacga
     8341 agctgccatg cggattgctt tttccttctc agctgacaaa tgccccaaat tgatgaagag
     8401 agcctgactt tgcttagtaa aatcaagaac ttcacgggga tcatctgcca tgacaggttt
     8461 gcatcccaga gccaaaatcc catttgccag catctcacaa gaaatctcat tggtcataca
     8521 gtgaatgagg gaactagagc ctataggaaa aggatttgtc aatgcctgca tcattctatc
     8581 ctttcagcaa agaaatatcc ttgcactttt ttaaagaatt cctgcttgat taaaaatcta
     8641 aatgcaataa aggaaatcgc tgtaccaatc aaggttgctc cgaaaaatcg aggagtgtag
     8701 ataaaccaac taagcttagc agccgatcct gtaaagagca ccataacagg ataggaaaca
     8761 atagaaccaa taatacctgt tcccacaatt tctcccaagg cagaaaagta aaattttcga
     8821 ccgtacttat aaaagagacc tgctagaagg gctccaaaag tcgctcctgt gagagctaaa
     8881 ggcggaatcc cttgagtcgt catacggata aaggctgtca ctgtagccat agccaaggca
     8941 taaacaggtc ccatcatgat tcccgctaga atattgacta cactggacat cggtgccatt
     9001 ccctcaatcc gaaagatagg tgtaaggact acatcaaggg caatcatcat agataaaatg
     9061 gtcaatttgt gaacttgtag ttggtgcttt ctcatgtttc tattcttctc ctttttctaa
     9121 agactgtaaa tcgctcttcc atgtctggtg ttggtaagcc atctcccaaa acttagcttc
     9181 catatgaaca ctgatgtgga aggcatctag cattttttgc ttatctgtct catcactttc
     9241 tcgataaagc tgattgacca gtgctccctc ctctctgatc tgttgctcta actcatccgt
     9301 aatataagtt tcaatccatt gttgatagag aggatttggt gatggtttaa gattaagtga
     9361 tttgcctata tcatggtata accaaggaca aggaagcaag cttgcaaaag ctatggctaa
     9421 gttcggttct gcaaattgcc tataaatatg agaaatgtaa tgataacagg ttggagcgat
     9481 tggatgttgc tccatttcct ggtcgttgat ttccaattcc ttgaaaaatt gttggcgaat
     9541 aaataactca ccctccacta aaccctgagc attttgtttc aagagtcttt tcatctcttg
     9601 gtttgaagtc ttatcagcca aaagatgata gatttctgag aaagccttca gatagtaggc
     9661 atcctgaatc aggtaatagc ggaaaatggc aggttctaaa ttcccctctt gtaattgtaa
     9721 aataaaggga tgatgaaagg aagcctgcca agctttcttg gataattcca tcgcaatatc
     9781 tgtaaattcc ataataactc ctttataaaa atagactggt ttgaagcaat aaaaagaaaa
     9841 gcaggtagat taattttgtt tttttaggaa tataaaaagt ccgatagcta ttcttcaact
     9901 gtgcatgttc gtcatatccg tgagcagata gagctctcag gtaaagatgg cgccacctaa
     9961 agactgtcat cagaacctta ctgtaaatca agggcgacca aaaatgtagt ttttgaccac
    10021 gtaataggca agcttctttg agggacttga tttcttgctg aatgagagga aaagaattga
    10081 ataccacaat caaggcatag gaccaagagc gtgatagccc cttttgagcc aagtacaaga
    10141 gaagctcttt tagtgaaata gaggaaacaa agacaaggcc gatacaaact gtcacaaagg
    10201 ccctcgttcc aagcatgact gcctgtgaag catctccgtg taactgaact gcccagtagt
    10261 tggcaaaaga tggtaaaatg gcaagtatga tcatccaagc taacatttta aatcgacggt
    10321 aatagagcat aaagagaata caaaatgcga ctaccgaaag attcagagca atcgaaggaa
    10381 tgaaagatgt ttccaaggat aaaatcagca agaagagact gataatcggt gtctgggttg
    10441 ctactttgac catactatct cacctcccct tgggtattgc tactctgaga tgtaagtggt
    10501 ttggtaatgg tcacttcttt cacatgccga agaccctgac tagtcatctc aatccaataa
    10561 tcaaccacag aaatcaaagg gtctaaacga tgactaatga gcagaaaact tcttccttga
    10621 ttcctctcct ccacaatcca cttgcaaaaa taatggcagg ctctatcatc caaacctgca
    10681 aaaggttcat ctagcaagat cacggaagcc ttactggtca agatggtcag gagctgaaga
    10741 attttttgct gaccaccact taattgatag ggactcttat cgactgcctg ctccaaatca
    10801 aaatatcgta aagcttgaaa aatccgctga tttctttcag aatcaggtcc atctaattga
    10861 agctcctctc gcagactgac tcggataaac tgcttctcag cttcctgaac aacacccgtc
    10921 agatcacggt acaaactctt tttctttttc aggactgtcc ccttccatgc aatgcgcccc
    10981 ttatactttt gaaattgaag aatagaccga aagagggttg atttcccgac accattgtca
    11041 cccaggatac aggaaatccc ttgatagaat gtgaaatcag caattgaaaa gagggggcga
    11101 ttaccaagct caccagtcac acggttcata tggaataatt ccgggctaga agcaacttcc
    11161 tttgaagcaa cctgtgtcat ctcataggaa gggatttgat ttatttccct tagttttccg
    11221 tctcttagct caaccatatg gtcgatatag gctttatagt cagataaatc atggtcgcac
    11281 aaaataactg tcttcccatc aagagccaac tcttttagaa tctccaatat ctcgattctg
    11341 ctcttgcggt caatggaagc gaagggctca tccaagagat ataccctagg attcatggca
    11401 aagaggacag ccagcgctgc tttttgcttt tccccacctg ataggtgatg aatgggacgg
    11461 tgtaagattg cctcgcaacg acattgctgg acaacctctg ctattttaga atcaatttcc
    11521 tgaaggtgat agccgatatt ctccaaggtg aaaatcaact cctcaaacaa gttctccatg
    11581 gtaaattgat gattgggatt ttgcaagaga atgccaacct tctggacacg tgcgatgata
    11641 gaaagctgac tgacctcgct cccatctatc aggacttgac cactataggg aagagaactg
    11701 acttgggcaa tcatttgaaa gaggctggat tttcctgaac cactgctccc aactaacaag
    11761 gtaaaggctt gcgcatgaaa agtaaaatca aacggctcag agaagattgg ggactgaatc
    11821 gctcgtagtt ccagacccat ctatgctttt cctccagttg caaactgatg atagagtttg
    11881 acaatggcac gaaccaagat ggtacagaag aaataaacag aaataaaacg taccacaagc
    11941 aaggaaagga caaacggaag ggaaaaggcg tagtaaccta acttaatgta ttcatagaca
    12001 aagctaacaa gcgtaatccc aatactatta gcagttagag agagccaact ttcatagcga
    12061 ttcttagtta cgataaaacc aaattcactt cccaaacctt gaaccaagcc agacaaaaga
    12121 gctcctagac caaattggct accataaagg acttcagcaa gcgcagctag cacttctcca
    12181 atcgttgcac ttccgactct cggaacaaag atggcagcaa tgggcgcagc catacaccag
    12241 agaccgaaga ggatttcatt ggcaaaggcc tgcaaaccaa gaggtgttaa gagtagactg
    12301 agaatattat acacatatcc tgaaccaacg aaaaccccac caaaaaagat agacaagaaa
    12361 gcaagcaaga taacatcttt taactgccat tttttcaaca taaaaaactc ctttttttaa
    12421 agaaaagtgg ggcactcaag aagaccgacc taaatacttt gtatagcaga ctgaatttag
    12481 aacagtacac aagaacacta aaatatttct agaaattaat ttgaattttc taattgattt
    12541 gttcgcatct tatttcaatc tactatatca tcttcatcca gtttcgtaaa agaaaaaact
    12601 ctaattacag atacgaatta gagttcagct tacaagatta gacagttctt ttcgacatac
    12661 gaaaaaaaca tttcacattt cccttcgcca gtcttaactg tatcaggttc aatgggtatc
    12721 atctcagcct aaagcacccc aaatgccttt attatttaat tatgtgatta ttataacaca
    12781 cattttatac tagttcaaga aattgaactg gaaatacagc cttgcactca caaagacagc
    12841 agatctttct tttgcaaaaa acaaatgacc tgtttgatga attagctatt caagctgaat
    12901 ctagacatag ctttttaaaa aaggaaaatc ctacttactt agaatccaag gatagatatc
    12961 tattgttcac tcatttcccg aacagttttt tctatatttt ttgcatacga tattgccgaa
    13021 atgattgaaa cgccgtcaac attggtcttt ataatgtctt taatatgttt cgtctgtatc
    13081 ccaccaattg caactaaagg catttgtggc aatagttttc tcatcaattc aagaccttca
    13141 taacctatag caccaccagc atcatccttt gactgggtat caaatacagg accaacacca
    13201 acataatcta catattcaac ttttgattgt tgaaattctt cctcgttttt tatagaaaga
    13261 ccaattattt tatctggcat caattttcta atttcatcaa caccaatatc atcttgacct
    13321 acatgtacgc catcagcgtc aatttccatt gctaaatcta tatcgtcatt aacgataaat
    13381 ggaacattgt attttttaca aagttcttta atttggatag ctagctcaag tttttctaag
    13441 ccttctaaag caccctcacc tttttctcga aattgaaata aggttatacc accttttaag
    13501 gcttcctcaa cgactgtata tagatttttt ccttggcaag tagtcgttcc acaaataaaa
    13561 tatagtttta gtaattcttt atgaaacatc ttacttcact cttttgaatt tcttgacatc
    13621 ttcatctgta atttcatata aggcatttat aaattcaact ttaaatgttc caggaagatg
    13681 tccatttgga cgtttttccg ccatttctcc agcgatattg taaaccaaca ttgctgtttc
    13741 taatgatttc aattcttgac ctttttcaag tccgataaag cttgctacta cagctcctaa
    13801 taagcatcct gtcccaatga ctttcggcat catagcacta ccattatgaa tcgttaccac
    13861 ttctccatta acagcaatgg catccacttc acctgttact actattggaa tattgaactt
    13921 ctcatttgct gctagagcaa tttcgtcaat attatctacg cccgcactat ctactccttt
    13981 agatgccaca tctattccta ctaaagaggc aatctctcca gcattccccc taatcgcagc
    14041 tagtttgtaa ttgttgatta aatcatctgc tacttttttt ctatattctc ctgctccaca
    14101 ggctacagga tctaaaactg ctgggacatt atatttctct gcaattttca gagcagcttg
    14161 gtataatttc caattttcat ctgtcaatgt tcctatgttt attaataaac caccagcata
    14221 ctttaataag tcctctaaat ctgctggaaa ctcactcatg gctggtgagg cgcccagtgc
    14281 tactaatcca tttgctgtga aattttttac tacatcattg gtgatgcaaa tgaccaaagg
    14341 tgctttttct tttaataatt ttaaacttgt catattgaaa tccttccttt tcactttata
    14401 cgatctacta atttcgattt atctttagtt gagaattttt ttcatttaca ttgaatgatt
    14461 tatactcaat gaaaatcaaa gagcaaacta ggaggctaac cgcaggttgc tcaaaacact
    14521 gctttgagcc tgtagataag actgacgaag tcagctcaaa acactgtttt gaggttgtgg
    14581 atagaactga cgtggtttga agagattttc gaagagtctt acctcatcaa atttgtaaat
    14641 atcatgagcc ttctctagac atcgtaacca atatcaaaaa aagctaattc taaagcgact
    14701 gcttgattcc agcgttgctg aagttctgtc aaatcttctc gatttttacc gacacgattg
    14761 agttcatcaa ccagaaattg aactcactct gcaaagaaag gacctctgtg gagattgatc
    14821 cattccgaat gaatatagac ttcaggtaga gccaaatctt tagaacccca gtctaaatag
    14881 agaccttctg caatgaccag cataaccaaa agatgggcat agtctgatga agccactgcc
    14941 caatacatta gatcctgaaa ggcttttgtt acagggtgca aagtcacttc tagatagtta
    15001 ttctctgcta cttttaactc tttaaaagcc ttttggaaat aaccatcttc atctgcttca
    15061 agaaagccta gttgcttggc aaaacgaagc ttggattcaa gtttatctgc gtgagctacg
    15121 caggcaccca gcatggataa gaaggcatca aagaagtgat aatcttgaat cagatagtcc
    15181 tttaagacct tattctcaat tgtccccgca aaaagttcct taacaaaacg atgattgatt
    15241 gcagcctgcc aatccttctg actgcttttt aataattctc caacagtcaa acctggctga
    15301 aatgcatagt cttgtgtttc catatttact tctcctctct ttacttgtta gtaattaata
    15361 aaacagcaag aaatatcaag caaaatcgta attccacttg atccttttaa agcacatcga
    15421 gagcatttac agagagctaa ctaaacaagc ctatccagtt tatataaaca aaaaactcca
    15481 attacaatca agaattagag ttgacttaca agattagacc gttcatttca ccatacgaaa
    15541 aaactgttca catttccctt cgccagtctt aactgtatca ggttcaatgg gtattatctc
    15601 agcctaaagc accccaaatg tctctattat ttaattactg aaccagtata gcaaaaaatg
    15661 aaagccctag caagatattt gaccgaaaaa tatctttata tacaatatat tgaaactaga
    15721 atagtacacc tctacttcta aaacattgtt agaaatcgat ttaactgtcc tgattgattt
    15781 gtcctattct tatttcattt tactatagtt ttcgatagcg atttattctt ccaatacacg
    15841 aagaaaaacc tccacattca gtgaaggcaa tctgttttat caatacaatt ttaagtcacg
    15901 agggtcaact gggaaggttg ggttgtatgg attgtgacgg agcttaaagt gtttgacatc
    15961 ttcaatggtc tgagctccag acaattgcat aactgtcttc aattccgcat tcaagtgttc
    16021 aaagacttga cgcacaccga cactaccacc gagagccaag ccataaataa cagggcgacc
    16081 aatagctacc aagtctgctc ctgaagccaa ggctttaaag acgtgttgac cacgacgaac
    16141 accagagtca aagacaatcg gcacacgtct atcaactgct tctgccactt cttgaagcga
    16201 gtcaaaggca gctggtccac cgtcgatttg acgaccaccg tggttggtta cccagatacc
    16261 agaagctcct gcagcaagtg aacgttcaac gtcctcacgg cattgtggtc ccttgacata
    16321 cacaggaaga ccagagtatt cagcgataaa ttctacatcg cgtggagaca agcgttgttt
    16381 agctgatttg taaacaaagt ccattgattt accagcacct tctggcaggt attcttcaac
    16441 aatcggcatg ccaactggga agacaaaacc attacgctta tccacttcac gattcccccc
    16501 tacagtagca tctgccgtca agacaatcgc tttataacct tcagccttca cacggtccat
    16561 gatgtggcgg ttgataccgt catccttact aaagtaaaat tggaaccaat ggggtgtccc
    16621 ttgaagggct tcagaaatct ctggaaggtc aacagtagag taagagctgg ttgtataaag
    16681 agaaccaaac tcatgcacac cacgcgcagt cgccacttcc ccctgttcat ttgccaattt
    16741 atgagccgca acaggcgcca taatgattgg tgaagatagt ttttcacctg caaattcaat
    16801 ctctgtactt ggattttcaa catcgcaaag tgtatgagga acgatgagtt tgtggttaaa
    16861 ggcgcggata ttctctctta aagtgaaagt atcttccgcc ccactagcga tatagccaaa
    16921 tgctgcttta ggaataactt gttgcgccat tggctccaaa tcataggtat tgatgaagtc
    16981 tacatgacct tctgcattgc ttgttttata tgacataaaa tgccctcctt gattaagtaa
    17041 gcgtttgctt tttactacac aactataata actctttttt caatcatttt caagagtttt
    17101 gcttaaaaac catcttattt tttcatacaa tatactagcc ctactttcct taaactctaa
    17161 accttagtct atattaagtg aatcgttgag attttttgct gccaggcatt tgaactactt
    17221 ttttatttgc ggattctatc tactaatact ataaaaaaaa caagtgaata agacaccaga
    17281 acatcctcta ataggaccta tggacttata tcagtcccat atatactgtt taagcaagat
    17341 actatcctag ttgacgctaa cttcctatcc cacttattaa ttttttattt atagtgaatc
    17401 tgaacaaatc aattggggaa tccaagtcaa tttctagtac tttttgaaca gtttcagcgt
    17461 actatcgtaa aatgaaataa aacatgcaca aattgattag ggaatttaaa ccaatttcta
    17521 acaatgtctt agaaatcaaa gtgtactatt tcaacttcaa tatactacac ttcattttct
    17581 ccttaaattc agtctctttt tgaatcaaaa atcctctggt aagagccaga gggtaagaat
    17641 ttatttcatt gttgggaaga gcaatacatc acggatagtt gttgtatcag tgaggagcat
    17701 gcagagacgg tcgataccga ttcccaaacc acctgttggt ggcataccgt attcaagagc
    17761 ctcgatgtag tcatagtcga tgcctgtcgc ttcatcatca ccaagttctt tagctttagc
    17821 ttgggcttca aaacggctaa gttggtcgat tgggtcgttg agctcagtaa aggcattacc
    17881 gtactcctta gtcatgataa agagctcgaa acggtcagta aagcgttggt cttcaggatt
    17941 tttcttagcg agtggagata cagctactgg atgtccatag acaaaggttg gttggattaa
    18001 agtttcttca acaaactctt caaagaaggc attgatgatg tgaccaacct cagtgtagtg
    18061 tttctcaact ggaactttct tctcagcagc gatagcttta gcttctttca aagtcatgtc
    18121 ttgccagaaa tcgacaccag taatttctct gatagcatcc accatatgaa cacgcttaaa
    18181 tggttcgtta atcttgattt cagtaccttg gtagttgact gggccatcgc ccttaactga
    18241 tttagcagca tgttggataa tgccttccgt caagtccatg atatcttgga agtctgcata
    18301 agcttggtaa acttcgatag aagtgaactc agggttatga gtagcatcca ttccttcgtt
    18361 acggaagata cggccaattt catagacacg ttccatacca cccacgataa ggcgttttaa
    18421 gtgaagctca gtcgcgatac gaagcaccat gtcaatgttt tgggcattgt ggtgggtgat
    18481 aaatggacgg gcagcagcac caccggcttc attatgaaga acaggtgttt ccacttcaag
    18541 gaatcctttt tggtcaaggt aacgacggat ttcagagatg atttttgaac gagtgacaaa
    18601 gcgttcaaag ctttcacgat tagaaatcaa gtcaaggtaa cgtttacggt aaattgtttc
    18661 aacgtctgtc aaaccatgga atttctcagg aagaggacga agagccttag acaagtgtgt
    18721 gatgtgggtt gccttgatag agagttctcc catatccgta cgcatcactt caccttcgac
    18781 accaaggaag tcaccaaggt ctgctttttt gaagatttcg tagttttctt caccgacagc
    18841 atccttacga acgtagatct gaatctggcc ttcgcggtct tgaaggtggg caaaaccaac
    18901 ttttccttta ccacgtttgg ttaccaagcg tcctgcgata gtagctgttt cgtttttatc
    18961 gtgtaattgt tctttatcga ggttggcata tttatctttt aattcttgtg aatttgcagt
    19021 acgttcaaaa cgttttccga aaggatcgat tccttgttcg cggagcgcag ccattttttc
    19081 acggcgaacg atctgctggt catttagttc ttccatatgt tctgtagaca tgggatcctc
    19141 ctagttttac tcaaaattga atacgatgag tcattttttg cgatactccc attttatcat
    19201 aaataagcaa gaaattcacg gataatcttt aaaaactaaa aagaacctga cgctaaaatc
    19261 actggaaaga agtgaaagta tcttccgccc cactagcgat atagccaaat gctgctttag
    19321 gaataacttg ttgcgccatt ggctccaaat cataggtatt gatgaaatct acatgacctt
    19381 ctgcattgct tgttttgtat gacataaaat gtcctcctta ataagtaagc gtttactttg
    19441 tatattataa aaatatatta actctttttt caaaactttt caaatatttt gtttggaaat
    19501 ttcagaaatt ttatgtctat gataaaaatc cttataacgg caataaaaaa tagatattat
    19561 ccaaagaaga ttttaagtgc tacaataact gtattatttc tagatgggag gttctatttt
    19621 tggattgatc cattgttgaa caatatctac cactatatca aaaggcattc tttctgacct
    19681 tgcatattgc agtttgggga attttgggat cctttctgct cggtttaatc gttagtatca
    19741 tccgacatta tcgaatccct gttttagcgc aagtagcgac agcctacatt gaattgtcac
    19801 gtaatacgcc ccttttgatt caactcttct ttctctactt cggtcttccc ctaatcggga
    19861 ttgtcctatc ttcagaagtc tgtgcaacgc ttggacttgt ctttttagga agctcctata
    19921 tggcagaatc tttccgaagt gggctggaag ccatcagtca aacccagcag gagattggcc
    19981 tcgctattgg tctgacacct ctacaggtct ttcgctatgt ggttcttccg caagcaacag
    20041 cggtggtact cccctccttt agtgccaatg tcattttcct tatcaagaaa acctctgttt
    20101 tctcagcagt ggctttggcc gacctcatgt acgtcgccaa ggatttgatt ggtctctact
    20161 atgagacaga cattgcgcta gctatgttgg tagttgctta tctgatcatg ctgctaccca
    20221 tctcactggt ctttagctgg atagaaagga ggacctgcca tgcaggattc gggaatccaa
    20281 gtactctttc aaggaaataa tctcctgaga atcttacagg ggttgggcgt tacgattggg
    20341 atatccatcc tgtctgtcct cttatccatg atgttcggaa cagtcatggg aatcatcatg
    20401 acctcccatt ctagaatcat acgattttta acacgattgt atctggaatt tatccgtatc
    20461 atgccccagc tggtgctact cttcatcgtt tactttggct tggctcgaaa ctttaatatc
    20521 aatatctcag gtgagacttc agctattatc atttttaccc tctggggaac agctgaaatg
    20581 ggagacttgg tacgtggagc tatcacttct ctccctaaac atcagtttga aagtggatag
    20641 gcactcggct tgactaatgt tcaactttac taccacatca tcatcccaca agtcttaaga
    20701 agactgctac cgcaggctat caatcttgtc actcggatga ttaaaaccac ttcattagtt
    20761 gttttgattg gggttgtgga agtgaccaaa gttggacaac aaatcatcga tagcaatcgc
    20821 ctgaccatcc caactgcttc attttggatt tatggaacca ttctagtctt atatttcgca
    20881 gtttgctacc ctatttccaa actatccact cacttagaaa aacattggag aaactaaatg
    20941 tctgaaacta tcttagaaat caaggaacta aaaaaatcct tcggagacaa tcccatcctc
    21001 caaggacttt ctctagaaat caaaaaaggg gaagttgttg tcatcctagg gccatttggt
    21061 tgtgggaaaa gtaccctcct tcgttgcctc aacggcttag aaagtattca aggtggagat
    21121 attcttctgg atggtcagtc tatcgttgaa aataaaaaag attttcacct agttcgccaa
    21181 aagattggca tggtctttca aagttatgaa ctctttcccc atctggatgt cttacaaaac
    21241 ctcatcctag gccctatcaa agctcaagga agggacaaga aagaagtaac ggaagaagct
    21301 ttgcaattac tagatcgtgt cggtttactg gataaacaac atagctttgc tttgctttgc
    21361 ccgtcaatta tctggtggac agaagcaacg tgttgcaatt gtccgtgccc tcctaatgca
    21421 tccagaaatc atcctttttg acgaggtgac tgcttcgctg gatccagaaa tggtgcgtga
    21481 ggtgctggaa cttatcaatg atttggccca agaaggccgt accatgattt tagtaaccca
    21541 cgaaatgcag tttgcccaag ccattgctga ccggattatc ttcctcgacc aagggaaaat
    21601 cgctgaagaa ggaacagctc aagccttctt taccaatccg caaaccaaac gagcccagga
    21661 atttttaaac gtctttgact ttagccaatt cggctcatat ctataaagga gattcttatg
    21721 aaactattca aaccactctt aactgtttta gcacttgcct ttgcccttat ctttatcact
    21781 gcttgtagct caggtggaaa cgctggttca tcctctggaa aaacaactgc caaagctcgc
    21841 actatcgatg aaatcaaaaa aagcggtgaa ctgcgaatcg ccgtgtttgg agataaaaaa
    21901 ccgtttggct acgttgacaa tgatggttct taccaaggct acgatattga actagggaac
    21961 caactagctc aagaccttgg tgtcaaggtt aaatacattt cagtcgatgc tgccaaccgt
    22021 gcggaatact tgatttcaaa caaggtagat attactcttg ctaactttac agtaactgac
    22081 gaacgtaaga aacaagttga ttttgccctt ccatatatga aagtttctct gggtgtcgta
    22141 tcacctaaga ctggtctcat tacagacgtc aaacaacttg aaggtaaaac cttaattgtc
    22201 acaaaaggaa cgactgctga gacttatttt gaaaagaatc atccagaaat caaactccaa
    22261 aaatacgacc aatacagtga ctcttaccaa gctcttcttg acggacgtgg agatgccttt
    22321 tcaactgaca atacggaagt tctagcttgg gcgcttgaaa ataaaggatt tgaagtagga
    22381 attacttccc tcggtgatcc cgataccatt gcggcagcag ttcaaaaagg caaccaagaa
    22441 ttgctagact tcatcaataa agatattgaa aaattaggca aggaaaactt cttccacaag
    22501 gcctatgaaa aaacacttca cctaacctac ggtgacgctg ctaaagcaga tgacctggtt
    22561 gttgaaggtg gaaaagttga ttagtcatta actcttaaaa ggaactggat tttaagatcc
    22621 aatccctttt taagatttta cctataacat cctgagtcta tctaagatgt tcaatctgaa
    22681 cacagtgtac atactttatc ttctattgca tatactttat cacataagat acgaatatcc
    22741 tcttcactat gactagcaat caaaattgtt gtcccttttt cactagagag ctttctaaac
    22801 aatgttctca tattttctac acttgattta tccaaggcat tcataggttc atctagtaaa
    22861 agaatagagg gattctccat aattgcttga gcaatcccta gctttttcct catacctagc
    22921 gaataagttt taactttctg gtctttttgc tcatatagac caactatttt cagtgtatca
    22981 ttgatttcct gattaccaac tactcctcgt atgcttgcca aatattgtaa attcttaaag
    23041 ccactataat aatttataaa accaggttct tcaatcaaag ctcccaaatt agctggaatt
    23101 tttctctcag gaacaatatt ttccccattg attaacactt ctccataaga cggactatat
    23161 aaaccagcta ttaatttaaa caatacactt ttccctgagc cattcgcacc agtaattcct
    23221 ataatttccc cctgtttaca actaaagtta aggttttgaa aaacacatgt tttttttaat
    23281 tccaactgaa tattttttaa tgtaattatt tcattcattc tataaacctc ctcttttgac
    23341 gagtgaaata gaaaatgctt ttaaaaagaa agactaaaaa tagcaactga agaaataaat
    23401 ctcgtcctat atctccattc cctcgattta aaatataaaa tagataatta gttcgatttc
    23461 ctacaaatag accaccaaac acaatcatga gtaaaaagaa gctaacacaa gaaaagttca
    23521 tttgctcatt cgctcctagt acgtataaca taaagcaaaa caagactaac acacaagcat
    23581 tcaaagaatc aactataaac aaaactccta tatcccagtt tggtaactgt aacataaatt
    23641 gaatcactag aacttttacc atgattaaaa tgagtccata aagaaaacag gtccaaatct
    23701 gatacctaat ccagagctta atagaagaaa atcgaatcac ttccataaag aaatcggatg
    23761 ctcttctacg atatacaact gctagaaaaa atgtatgaat aataaaccaa tgaagcaacc
    23821 atatagataa gactaaaaaa gagttttgac tcagattagg cccttttaaa atttctataa
    23881 caagtctatc atttccttct aaccaatacc ataatcctaa acaaatcaat atccaaaaaa
    23941 gaacataacc ccaaaagtac ttggtataga ttatctgatt caacctccac atgtgactac
    24001 ttaactttcc catttccaac ttttacactc tcctccagtt tctatgaaca gaaaatacag
    24061 tcaatggaat tatgatagat agtaatgtaa gccaataaat caatgcatac ggattggaat
    24121 ttaccatata ctgaaaaatt ggcaataatc caattatccc attgtccaac tgataaatcc
    24181 agaataagga ttctacaaat aaaaaagtaa acagaaatac taagctcatg tttgattttt
    24241 taaaccaaga aaaactgcta atagtaagta aggataaaaa gaaatagtat gctatataag
    24301 agaaaaaaaa tcctataaaa aaactagcat tgtttgcaat acttatacca taaaattctc
    24361 ttaaaaaatc aacctccttt atctccaaag agaagctaaa accattacta aatgcaatca
    24421 gaaaaatcaa taaaaataaa gtcgccgtcc aaatccccgt actaagagct gctaatttga
    24481 aactaaaact ggtaaagtgc ttaattgatt tcagacgaat acgacactcc aacctattaa
    24541 aatagttatt catcaaataa aaaaagaata atatatatgt gaacggaaag caatatactc
    24601 cagtcgtcat atcttgaagt aaaactaaga tccattctaa tacatttgga tggattgaat
    24661 attggcgaca gcgcaataaa tatactgtac tagataaaac acaggatagc agtaatataa
    24721 aataaaccaa tactgctaag aaatcttttt tataaaattg aacaaattgt ttcattatac
    24781 atagtcctct gaatgtagaa aaaatgtacc ataaacaacc aaacaactaa caaataaaat
    24841 aaaagcaaga tgcccactaa ctaaggaaag actgatatct ttctgatatc ccaaagctag
    24901 cgttgtcaca ggttctaagt aagatagccc taaaatagcc cataaaatac caccaaccat
    24961 catataggca actgggatga aaatagctcc taattttttc ttcactagca aagcactagc
    25021 tagtccaaaa atagagaaca cagcgcccca aactccatac cagagagtcg tcacaagact
    25081 atagagaaac tgattggaat caaataattc ttttaaggca ccactataat ctccaatata
    25141 aatttcctga taaggagtca ctaaaagatt aattcctaat aataataaat aggggagaaa
    25201 aaagactaga aaagaagaaa taattgcagt actacctaca atagctagat acctcttttt
    25261 agaaattcgg cacaattgtg ctgttagaaa atgactctca gcatcctcta ttatctgact
    25321 agaatagggc agtgtacaga taagtgcagc tactaggcta atcggtgaaa atcctcgaat
    25381 agaagaagcg gcaaaaaaaa tcgataaacc ttcaatttta taaataccat tgaaagcaag
    25441 gaaatttcct aaactcatgc aaagaagggt caaaaataaa gacatataaa accgaggtga
    25501 ttgaacgact cgtacaagat tacaaatgaa aaattccatc cttactcctc cttataataa
    25561 aaatagggtg tagcattctt ttttcatgct acacccacaa tcaaccatct ttaaggctta
    25621 ctctgacaag taagttaata agaatctgga ctccaagaac ctgaagtatg aattcttaca
    25681 taatttccaa attgtggcgc catagctaat ctagtaccag aaccaatata attgtcacca
    25741 cctccattat agtacatgac aatcctagag ccagacccca atgaatatac cggggtaata
    25801 tctgacccac tataggcgct acgaatagag gtatttaacc ttttaccgcc accagtgctg
    25861 tcactattat taattccagc agaggcgttt tctttctcaa gctcactagt tgtatccgaa
    25921 ccccaacgcg gcaacgttaa atcataattt ccaatctgtc tagctaaaac tgtagggaga
    25981 aacaaactag atgcaattgt aactacgcaa aaaaggaata tatttttctt cttttcatga
    26041 catcgtcctc ttaagaagtg ataaacaaga tagttgattg atcaatttga tacatattac
    26101 attttcatta tatcaataaa agaaagcgtt gtcaattatt ttatttaaaa tattgtcata
    26161 ttttaaataa aatggtaaaa gagactcggt agcctcgtct ctctttatct tactgaccta
    26221 accttcttgc caattttctt ggtcttcttt aaagcgtttt agaagatcaa ggccctctgg
    26281 cgtgatgtaa ccttcttctt gggctagatg gataagctcg ctatagtttg aaagcgtcac
    26341 aagtttaaca ccagcatctg caaagttctt atctgctttt ggcaattggt agctgaaaat
    26401 cgctacaact ccaagtacat ctgctccttc tcgcttggct gctgctacag cttcaagaac
    26461 tgaaccaccc gttgaaataa ggtcttcaac cactaccatt ttttgacctt gagctacgcg
    26521 accttcgatt tgattaccag ctccgtggtc ttttggtttg ctacggatgt aggcaaaagg
    26581 caagtccatc ttatcagcaa taatggctcc gtgtggaatc cctgctgttg cagttcctgc
    26641 aatcacttct acttcaggaa aggcttcttt gatagcttcc acaaaaccat tttcaattag
    26701 ggtacgagtt tctggatagg ctagtgtcac acgattatca gtgtaaatcg gtgacttgat
    26761 accagatgcc caagtgaagg gttcctctgg tttgaggtaa acggcttgga ttttcaagag
    26821 gtggctagcg atatctttag caagtgtcat ggtattctcc ttttattttt ctaatctagt
    26881 tctttaattc cagtcctgtg tccattcatc cttgatggca tgataagctg caacaggatc
    26941 ctcagcttgg gtaatgggac gtcccactac gatatagtca ctgccgattt gataggcatc
    27001 agcaggtgtc atgactcgtt tttgatctcc aactgcaaca ccagctggac gaatccctgg
    27061 tgtcagacag ataaaatctg gattggtagc ctgcttgatg acttgtactt cctgagccga
    27121 gcaaacaaca ccatccaagc cagcttcagc tgtcttcttg gcatagtgaa tcacagactc
    27181 ttgcagactg gtttggatat tttgaaactc ctgcatctga gcttctgacg ttgatgtgag
    27241 ctgcgttaca gcgatcaatt tggcttgact cccaagacct tcacgcgccg ccttcatcat
    27301 ctctacacca ccagccgcat ggacattagt catatcgaca ccaagctgag acaagacctt
    27361 catggctgac ttgactgtat taggaatgtc atgaagtttg agatccaaaa agacactatg
    27421 acccaaacct tttaagtagg acacaatctc aggccccgct gcgtaataaa gctccatccc
    27481 taccttgaga taaaggcttt cttctgctgg gaaaagagct aaaaattcct tgaccgcctc
    27541 aaaactagga aaatcaagag caatgattgg acgatgttct cgcataggtt tctcctttta
    27601 cctttactag tgagagagtc tggccaacag aagccacgaa aaaaggaacc tgccaacagc
    27661 aaggttccac gaaaaatggg tagtctccac cctttcaccg tctaacctta gctgcctctc
    27721 tggactgctt taaaggtttt ctattattct attatttcta ctagcacttg tcaagtaaaa
    27781 acatggtcac taaagaacta taagagaaaa ggtaaaccta gcgacgcgat gagcgctggg
    27841 tcgtttgatt tcgattgctc tcttcctctt gttttttctg ttcttcttcc tgttttttct
    27901 cggcttcctt ggcctcttgt ttggcttttt cctcagcctc cataattaat ttatccgcca
    27961 cagtgtaact gtaaattcca gcttccatgt cgaccacact cggttctgac aattgtggct
    28021 taatcttact gtaatatggc agtttcttac tcatttcaga tagaggaacc aagacttcgt
    28081 ccgaatcatt catggtcaat cgaattaaat cggatgtcac cttgcttggg gctaattcca
    28141 ccttttggat agccgccttg agttctgggc taatttgagc aagttctgag acaaaaacct
    28201 tgatttgttc actatcatta aagagaactg ataaataagt ttctggtaaa ctgttcagac
    28261 tcacagaact agtctcaagc tgaccactgg aaagaatagg ataatgattt tcaccagaaa
    28321 tatagtaggc cacaatatca tattccttga ccttaatagt gaacttagtt ggaaattgat
    28381 agacaagttg agctgattca acccaatagt tagacttaat ctgcttttca tattttgcct
    28441 tgtctagcag aaggttaatc gtataatccg aatcctgaat gcctgaagcc tgtcgaatat
    28501 catcagctgt agtttgcacc gttccctcaa cacgaatatc tttcatggtc gcataaggac
    28561 tgagcaagta ggcagagaca atcaataaaa gcagacttgg aaataaaatc gtgaaggctc
    28621 gcaagatatg gataccagga atctttgctt tggctggttt ttcctttgta gcctttttag
    28681 aaagcttttt atcctgttcc tccttctctt tagactctgg ttcttctttc tcttctttct
    28741 ctttgtcagc ctctgaggat gctacttttt cttcagactc ttccttagct gattctgaat
    28801 cttcctggtc tgtttcactc tcctggtcct gtttgtcctc tgacttctca gattcttctc
    28861 ccattcgagc ttgtctttcc ttttccttct cctcagctag agccgcctct tcttcagcct
    28921 tcttttttag atattcttgg tttcgtttct gccattctga taactctttc aattcttcga
    28981 ggatttcttt gtcctcattt ttcttatctt ttgacattta ctttccttat gataaatctt
    29041 ttttcaacaa ttgataaaaa tctgctagag atttcaattc cttagaagcc ttcatcttag
    29101 cttggtaatc ttccttgtga cttagtaagt gagaaagctt ctcttccaaa ctatccaagg
    29161 tcaaatcgct ttcttgaagg tcttctgcat agcctttttt tacaaagtaa gctgcatttt
    29221 caagctggtc accacgacta gcttcacgac caagcggcac aatgacatgc aattttgcta
    29281 tcgccaagag ctcaaaaatc gtattggcac cacctcgtgt cacaacaata tcagccaatt
    29341 ccatcaaggg ttgatagaga tcggtcacat agtcaacacg aaaaagattt tggctcaact
    29401 cattcaggct agaatctcca gttagattga taatattgta gcgctctgtt agttctttct
    29461 tatggtctgt caccaattgg ttaaagacac gagcacctgc agaaccgcca acaaacaata
    29521 cagtcggcaa tttatgatta aagtggcttt gaatatccac caattcatct ggttctggat
    29581 ttttttgatc tgaaaccttg gtcactgctc ccacatgctc aaccttagac aaactcgaag
    29641 cttgctcaaa ggttgaatac atcttagtcg caaatttata ggcgatttta ttggccaagc
    29701 ccatagacag gtcagattcg tgaataaaga caggcactcc tgacacacgc gcagcgataa
    29761 caggcggtac tgagacaaag cccccctttg aaaaaagggt ctgtggacga agtcgcaaca
    29821 tgataaagag cgattggacg attccccagc aaactttgaa gacgtccagc atattttgcc
    29881 aagagaaata gcgacgcaat tttccagtcg caatagaatg gaaggtgaca tccaaacctg
    29941 acttaaggat ttcttggtgt tcgataccac gcttgtcccc gatatagtgg acttcccaac
    30001 catcttcgat gaacttgggc attaacaaaa gattgagggt aacgtgtcca accgtccccc
    30061 cacctgtaaa gacaattttt ttcatattat tcttttaact ccgctactgt gtcgataaag
    30121 aggtcgccac gtacttcaaa gttagcatac atatcccagc tggcattggc aggactaaga
    30181 agaaccacat ctccttgagt cgcaagctca taggccttgc gggtcgcatc tgcaatatct
    30241 gtcgcctcca cataagcgac accagccttg tctgctgccc gtttgacacg ttctgcagat
    30301 tgacccagga tgaccatctt cttgagtcca gtaatgtctg gcaccaattc gtcaaactca
    30361 ttgccacggt ccaaaccacc tgcaatcaag acgaccttgc tgttatcaaa tcctgacaag
    30421 gctttttgag tagccaagat attagttgat ttactgtcgt tatagaattt aacacccttg
    30481 atgtcatcca caaactggag acggtgtttg acaccaccga aggctgaaag agtttccttg
    30541 atggtttgat tgtccacacc acgaagcttg gctacagcaa tagtcgcaag ggcattttcc
    30601 acattgtggc tacctggaac accgatttca ttcgctgcca tgactacttc accacggaag
    30661 tagagttgac catcttccag ataagctcca tcaacctttt caagtgttga aaatggtaca
    30721 acagtggctt ctgtcttgga agtcaagtct tttgccaagt cttgattaaa gttcaagaca
    30781 aggaaatcag ctgctgtcat cttgttctgg atattccact tggctgctac atattccgaa
    30841 aatgacccat ggtagtcgat atgagttggc atgaggttgg taataaccgc aatctctgga
    30901 tggaattctt gaacacccat gagttggaaa gaagaaagtt ccataacaag cgtgtcctta
    30961 tctgatgcta tttgagcaac ctgactagct ggatagccga tattccctga taaaagacca
    31021 tgttgcccag cagcagtcaa aacttcccca atcatagtcg ttgtggttgt cttaccgttc
    31081 gatcctgtga taccaataat cggtgcttct gaaatcaaat aagccaattc cacctcagtc
    31141 aagactggaa ttcccttggc caaagccttt tcaatcatgg gattgttgta ggggatacct
    31201 ggatttttca ccataagggc aaactcttca tccaagagtt ccaaaggatg gccacctgta
    31261 atgaccttga tcccttcttc cagcaaactt tgggcagctg gattgtcctc gaaaggtttc
    31321 ccatcattta ctgtcacaat ggcacctagc ttgtccaaca aacgagctgc agattcacca
    31381 gacttggcca aacctaaaac aaggactttc ttatttttaa attgatctat tactttcatg
    31441 tctcgaactc catttctact cctactattt taccattttt atggaaataa aaaagccaca
    31501 aagtgtgttt gtgactcttt cttctaactg aatcttacca tatcatctat gtgataaatc
    31561 ggtaactcga atgacctgat ccacttgttc ccaaatcaga ggattgtggg tcgcaataat
    31621 aatggtccga ttcggatttt ttaaagattc taggatggaa agtaattcct cagagttttt
    31681 ggggtctaag gaagtggttg gttcatctgc gaggatcaaa ggtggatcct ttaaaattat
    31741 cttcgctaat gcaacacgtt gtgcttctcc tcctgataac tcaaatatag gttgcttcaa
    31801 atccaaataa gagaggttta cacagtttag agcttgtttc atcaaagaga ttttctcttt
    31861 ttccttcaac tttttaccaa ctaaacccag attgagattc tctttgacgg tttggctttc
    31921 aattaagcca aaatcttgaa ataagtatcc caagtaatct ctaaagaaaa cagaaggctt
    31981 gatgtcctta agagaagtac catcatagat gatttgtcct ttgtcatatg gctctaatcg
    32041 tccaatcata ttcaagaatg ttgtcttacc acagccactt gtaccgatta aggcataaat
    32101 tttcccacct tcaaaatgaa gatttgtatc tgaaaatagc tgacggcttc caaatttttt
    32161 agatatattc tttagttcaa tcatcctatt ttcctttcat aattgtcata gaaacacgag
    32221 attctttctg cgcttgacgg taaagcgtca gaactgcact agctagaaag actaataaag
    32281 tgagcaagcc aatcaccaag tctcgactgc ttaaaataaa gagactagca ccaaatacaa
    32341 aactggcaaa ttgactaacc atatactgag catgtgtttc aaaaaatcgt aaacctgaaa
    32401 ttcgtttaat caaaatatct cggcggaatt gctcgaaata tagaagattg acagaataaa
    32461 atagtaacaa ggaactagct atccccacaa tagctcctaa gattaaagtt gctgtttcag
    32521 tttgaacttc attataacga gttagataaa cacttcttcc ttctttaaga taggatactt
    32581 gctcataaat tccagctttc ttcaagagtt ctagcccact ctcatatcct ttgataaaga
    32641 gttgttttcc agcattgata gaccaactag ataaggatat aaaactatca cctgtagaag
    32701 tcggcgtgaa taccactaaa atcggatcag tcaaatactg agtagatacg ggattctcac
    32761 cgttattata aacaaaccgc ttttccccca ttgaaagata actaacgtgc gctttcatct
    32821 cataatccaa aggagcactt gcctcctcac cagattttcc ataataactc aatctttctt
    32881 caaaaacttt cttaagttct gcttctcgag agcgcaaatg ttctgggagc aagaggataa
    32941 actcaccttt ttggagatgg gctaacttct gtttggtctc agcatctacc acgacctttt
    33001 ccttgtccaa ataactggga ctaacataga gcgtattagc atctggacta taggtatcca
    33061 gtgtctctcc ctgttcattt tttccttgtg gattggcaaa atggagcaga ttatccttta
    33121 cataaagagc ttgttcttct tcgattgctt ccttggcaaa ggcataccac ttgctctgat
    33181 tttctgtatc ttttcctcta tcacctaagc caaaagaaat ttgataatag tctgctctat
    33241 cctgccatgc ttgttttgaa atttcaagtt ctttcaatcg ttggtaagac atcaaacctg
    33301 tcttaacagc gtagcctact gtaaagacag caaccaactg acacaatagg gttaaaatca
    33361 tcaggcgttt aaggggtaat ctccccttaa taacgggaac taatgctttg taactcaaac
    33421 tcattagata aagaagcatt agtaaaattg aaatcgccaa taaaaacaac agatagaaac
    33481 taatcccaaa accataggtg gctaacaaga taggataaaa caaaccttga ctaaaaagaa
    33541 cgactccccc acctaggaag gaaaggaggg ctgatagaag gagccatttg atatcagtag
    33601 ataaagaatg ccccatgatg gataagagag tctgaccaga aaagagtttt atacctgctg
    33661 ctctcatttc cttaatccga gtgataatca ctaaagcaaa gaaagataag ccaaatattg
    33721 ctaaactaat taaaataagg ggatttagta atattcgaaa agcaagaaaa tagggcggta
    33781 tctttcggtc agcacttgct ttataaccca aatctcctaa tttatcggca agcttttctt
    33841 tcgtcaagga gcctgacaaa aggagataac tatttagcgg atcactacgt tcacgacttt
    33901 cttggctagc ttcttggaat tcttttggta aagttccctg accataagtt gcataagtaa
    33961 agtgagtcgt cccatcctta ctcggctcta caattcttct agctattaaa ctctgttctg
    34021 agtttgcaaa attctccaat tcctgttcaa atacctcacg cgtcggttcc tgagtatctt
    34081 ttttgacacg aagtaaagaa acggaatcat agcttgcata taaatattgt ggcgcacgta
    34141 agacaataat ccaagcaagg aagaagctga gaaaaaagtt gataataata tgaatagttt
    34201 cttcatagta gactccttgt aaacaaaatt ccccctgtaa tttcttacaa ggggaacgat
    34261 ttaaatcaat gaacgattag tcataatcac agtaaaatgc tacttgttct ccccatttag
    34321 tccaaatcca tgcataggag gtttttccag cagaagcttc tcctttatct gaatgactat
    34381 tccatctact tacaagagaa gaataatgat attttttacc atgatagtaa tttgaaaaag
    34441 cccaaccacc tcctgaacct tctccatacg tccatactcc tccatctgga tattgtacag
    34501 cagctgatgc agctcccaat aatgtaaaac ttgaaataag agctagagca agtaatctat
    34561 gttttttcgt tttcatttta ttttttcttt caaaaaaagc acaccttgag caacaatgca
    34621 acaaaataaa ccctcctctc tcttttgttg aaaccgcttt cttatgtgat aaaaatatca
    34681 tttttattat ttgttgtcaa ggaaaaaatc gaatttttta gatattttac tacattgcct
    34741 ctatgaataa tattatatag tagttttatt ttaaaataat atgcaaccag tactaaccaa
    34801 atataaaata gatgccatta acgaatttta ttcaagtttt tcccattcat actatccaag
    34861 caaaagagat gatgttatag tacaaaacaa ttcaaactat tgtaaaattc ctagcaaaaa
    34921 agagagccaa aactctcttt tttatcttct tttacttttt ttgactggca tgagtgtaat
    34981 gtctctaaca ctaaagtaag ctaggatcaa catggctatt gctaggaata tttctgttgg
    35041 taattgaaaa attttcagaa aagatagaac caataaaatc aagagtgcca ctaaaataca
    35101 taccatagcg acgatattga ctgtcccttt aatgctttct ggtgtcgcaa atacatagag
    35161 taggagcagt aaaattccta ggactaaata gaccatcttt ctctctttct agctcttatt
    35221 cagctgattt tttcttcttg ttagctttct cacgctctgc tttgttaagg atttgtttac
    35281 gcaaacggat agactcaggc gttacttcca tgtactcatc gtcgttcaag aactcaagag
    35341 actcttcaag tgtcaagata cgaggcgtct tgataacagc tgtttggtcc ttagtagctg
    35401 aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac tgtcaagtca ttttcacgag
    35461 agttttcacc gatgatcatt ccttcataaa cctcagtacc tgggttgaca aagatcgtac
    35521 cacgttcttc gatagacatg attgagtaag ttgtagcctt accagcatcg atagaaacaa
    35581 gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa tggcaagtat tggtcgaagg
    35641 tatggttcat gataccgtaa ccacgagtca ttgacaagaa ctcagttgag tatccaatca
    35701 aaccacgcgc tggaacaagg aagaccaaac gagtttgacc attaccagtt gaaatcatat
    35761 ccaacatttc acctttacgt tcagaaaggc tttggataac agacccttgg tattcttctg
    35821 gagtgtcgat ttgtacacgt tcaaatggtt cacatttaac accgtcgatt tcttttacga
    35881 taacttctgg acgagatact tgaagttcat agccctcacg acgcattgtt tcgataagga
    35941 ttgacaagtg caattctcca cgtcctgaaa cagtccattt atctggtgaa tcagttgggt
    36001 caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa gcgttcttcc accttacgag
    36061 aagttaccca tttaccttct ttaccagcaa atggtgagtt gttgaccaag aaagtcattt
    36121 gaagagttgg ctcatcgatg tgtaggattg gaagagcttc tactgcatct gtcggagtga
    36181 tggtttcacc gacaaagatg tcttccatac ctgaaacggc aatcaagtca cccgctttgg
    36241 cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa gagttttgta acacggaagt
    36301 ttttagttgt accgtcaagt ttagaaaggg taacttggtc cccaacctta actgtaccac
    36361 ggaagacacg accgataccg atacgtccaa cgaagtcatt gtagtccaaa agtgacactt
    36421 ggaactgcaa aggctcatct gagttatcta ctggagctgg gatatggtcg ataatcgtgt
    36481 caaagattgg tgccatagtc gcttcttggt cagctggatc atctgacaat gaagaagttc
    36541 cgttgatcgc tgaagcataa accactggga aatcaagctg gtcgtcatct gcaccaagct
    36601 cgatgaaaag ttccaagact tcatccacta cttctgctgg acgagctgat ggcttatcga
    36661 ttttgttaac aaccacgatt gggacaaggt cttgttccaa ggcttttttc aatacgaaac
    36721 gagtttgtgg catggttcct tcataggcat ctacgaccaa gacaacaccg tcaaccattt
    36781 tcatgatacg ctcaacttct ccaccaaagt ccgcgtgtcc tggtgtgtcc ataatgttga
    36841 tacgagttcc gttgtaagca acggcagtgt ttttagcaag gatggtaatc ccacgctctt
    36901 tttcgatatc gtttgagtcc atagcacgct ctgccaattc agtacgtgca tcaagcgttt
    36961 ctgattgttt caataattcg tcaaccaggg ttgttttacc gtggtcaacg tgggcgataa
    37021 tcgcaatgtt acggatatct tctcttaatt ttgtcatgat ttcctctata atattcaaaa
    37081 tttattttct aactgaacga ttataccata atttcaaata aataacataa ctcaagcaag
    37141 tgtaaatgtt ttcactccgc ttttcttttc acgtcaagcc ttttcaaagc aagcgactta
    37201 tgataagata ggcacagtat gcgtttagat aatttattag cccaagaaaa agttagccga
    37261 aaggccatga agcaagcact cctcagaggg gaaattctag tcgatggttg cccagcccgc
    37321 tccctagctc aaaatatcga tacaggacta caagaactcc tttttcagga tcgaatcatt
    37381 caaggctatg aacacaccta tcttatgctt cataaacctg ctggtgtcgt tacagccaac
    37441 aaagacaagg aacttccgac cgtcatggac ttgcttccat ctgacatcca gtctgacaag
    37501 ctctatgccg tcggccgact ggaccgagat acaacaggac tccttctctt gaccgataac
    37561 ggtcccttgg gcttccaact cctccatccc caatatcatg tcgataagac ttatcaagtt
    37621 gaggttaatg gacttctaac acctgaccat atccaaacct ttcaaaaagg aattgtcttt
    37681 ttagatggca ctatctgtaa acctgcaaga ctagagattc tatcagcaag tccttccctc
    37741 agtcaagcct ctatcaccat ttcagaagga aaatttcatc aaatcaagaa aatgttcctc
    37801 tcggttggtg ttaaggtgac taacctcaag agaatccaat ttggggactt cacattgaac
    37861 ccagatttag cagaaggtaa ctaccaccct ttgaaccaaa aagagttaca aatcattaaa
    37921 aactatttag agatgagtcg ataaaacaaa aaaagcttta aaactaaagc ttttttcttt
    37981 tatttaccga aaaattaagg cgattgctac aatccagtta actacagaaa tcacaattcc
    38041 taagatatta agaatctttt ctattttata gtctaattgt gactcttttt ggtatgaaat
    38101 agccaagacc aatcctatga tacccaaaat caggcctaca attggaaata acaaaccaag
    38161 aataatcgac aagataccca caaaaagtgg atttttcttc ttttctttca tgttctaaga
    38221 actctttaaa ttttatacaa attaattata ctataaaaca atagcttcat tctatcattc
    38281 gactaatttg gaaataaggt tagctagtct tcactttccc tttccaagaa tccaagccat
    38341 aagaaaggat ataaatctca gaaaaacctt gttttttcaa gtaaagagct gcatttgtaa
    38401 ctcgttgcgc acgttggttt tcgtagagaa ggacaggttt atctttacga agggctgcaa
    38461 gactagtttt caactgactt gaaggaatat tgcgtgcacc aaggatatgt tttctgtgga
    38521 attctgctgg gtcgcgcaaa tcaatcaatt gacccgtacg aatcaaggct tcaaactcct
    38581 cattgtccac aattttagcc gcacggcgaa tacgaagata gttaaagccc atccacgcca
    38641 acattgctag tataagtgcc cacaaaatcc aagtaaccat tagttctttt ctccattttt
    38701 ctcaatataa tccaattcta ccttgtgctc tctgcgaaga actgcttctg cctctagata
    38761 gtctaattta tccatcaacc ctgcatcgta aatccgagat agttccaact tcatcagttc
    38821 aatatcatat aagcgttttc ccatgtaaac aataatacca aatcgtttga ggaattgctg
    38881 cacatcatag aatgttttca taagactcat tctagcaaaa ttttgtgttt ttttcaagaa
    38941 gagactcaca caatgctcct tattttccta tcttctttag cgattctaag gcaagtatgg
    39001 tacaataaaa acatgagaat tcaacaatta cattatatta tcaaaatcgt cgaaactggc
    39061 tccatgaatg aggcagccaa gcaactcttt atcactcagc caagtctctc caatgcagtg
    39121 cgagatttgg aaaatgaaat gggcattgag atctttatcc gcaatcccaa gggaatcacc
    39181 ttgacccgtg atgggatgga gtttctctct tatgcccgtc aggttgtcga gcagacccag
    39241 cttctggagg aacgctataa aaatcctgtc gcccaccgcg aactctttag cgtttcgtct
    39301 caacactatg cctttgtggt caatgccttt gtctctttgc tcaagaaaag cgatatggag
    39361 aaatacgaac tcttccttcg tgaaactcgg acttgggaga ttatcgacga cgtcaagaac
    39421 ttccgcagtg aggtcggggt cctcttctta aacagttaca accgtgatgt tttaaccaag
    39481 atgctggatg acaatcacct gctagcccac catctcttca cagcgcaacc gcatatcttt
    39541 gtcagcaaga ccaaccctct ggcaaagaaa gacaaggtga aactgtctga tttggagaat
    39601 ttcccttacc tcagctatga ccaagggacg cacaactcct tctacttttc agaagagatt
    39661 ctttctcagg aacaccacaa gaaatccatt gtggtcagtg accgtgccac cctctttaat
    39721 ctcttgattg gtttggatgg ttataccatt gcgacaggga ttttgaacag caacctaaac
    39781 ggagacaata tcgtttctat cccactggat attgatgacc cgattgagct ggtctatatc
    39841 cagcatgaga aaaccagcct atctaagatg ggcgaacgct ttatcgacta tctactagaa
    39901 gaagttcagt ttgatagttg agaaatgata agaaccaata tgtaggctag caacaacctg
    39961 cacattggtt ctttttactt ataattaaaa gtttcccctg ccaacttatc agctagcttg
    40021 ggaaagagag tataaaactt atgggctagg ttcaacaaaa tcgggagatt gagttctcgt
    40081 ttatttttgc ctataatctt gacaatcttt ttagccactg catctgcctc taagaggaag
    40141 cggtcaaccg atttaagata agttccatct gggtcagctt ggtcaaaaaa tcctgttcgg
    40201 attggacctg gattgactgt tgtcacatag actccatagg gcataagttc gagtcgcaga
    40261 gcatttgaaa aaccaatagc cgcaaacttg gtcgctgagt aaagactaga cttgccagta
    40321 gctattagac ctgccatgct gacgatgttg atgatatgcc ctttgctgct ttccttcata
    40381 cgagccgcaa ggtgacgaga cagattcatc agggcaaagg tattgacctc aaacatctgg
    40441 tgaatatctt tatcagcaat ctggtcaaat ccctcaaaaa tcccgtaacc agcgttgtta
    40501 atcaagacat caatcttgcc atagcggaga taaagatcag ttaccagagc ttctagggct
    40561 gaatcgtcgg taatatcaat ttcaatcaat tctgcatggg aataatttcc gtagagttgg
    40621 gctaattttt ccttatttct accaagcaag atgagttggt cattgggcag gagtttgacc
    40681 atttcttgag ctagaccacc gctagctccg gtaatgagaa tagtaggcat acttatcctt
    40741 tctgtgactg ctagatttcc acttcttcca agtctttgac cacatggaca ttttcaaaaa
    40801 ttgtggcagc gtccttcttg agtttgctta tatcttttga gaggaaacgg gcactgatat
    40861 ggttgagtag gaggcgtttg gcacctgctt ctaccgctac ttgtgcagct tgcatattag
    40921 ttgagtgacc atggttacga gcaatttttt catcaccctt gccataagtg gactcatgaa
    40981 ctaggacatc tgcattgaca gccagacgca cactggcatc cgtttttcga gtgtctccta
    41041 aaatagtgat aatcttacct ggacgtggcg ctgagatata gtctgctgcc ttgatttcag
    41101 ttccgtcttc caaaacaaga tcctggccgt ttttgatttt accaaaaagc gggccgaacg
    41161 gaacaccagc agccttgagt ttttcagcat ccagcgtccc ttctagatcc ttttgcatga
    41221 cacgatagcc aacacagaaa atagtgtggt ccagctcctc tgcatacaca gtgaatttat
    41281 cggtttcaag aattttaccc agagaatctt ggtcaaactc atggaaatga atgcggtagg
    41341 gcagacgaga acctgacaca cgaaggctgg ttaagacaaa tgacttgatt ccttgaggtc
    41401 cgtagatttc caaatctgtc tgctcttcat tggcctgaaa ggcacggcta gaaaggaaac
    41461 ctggcaaacc aaaaatgtgg tctccatgca gatgggtaat aaagattttg ctgaccttac
    41521 gtggtcgaat tgtggtttcc agaatgcgat tttgcgtacc ttctccacag tcaaagagcc
    41581 aaacttcgtt aatctcgtcc aaaagtttca gggcgagact tgaaacgttg cgggctttag
    41641 agggctgacc agcccccgtt cctaaaaatt gaatatccat tcgatacttt ctaattaatc
    41701 aatatataac atggctgtgc ggttttccga tcggaaatag cgtttgccag aaaaagcagc
    41761 agcttcttgc aataaatcct cttggctgta gcctttgaga cgttttcgac catcagccaa
    41821 tctttccaaa tcagtcaaag ctgtgagact ttctaggctg acaacttcct cgtccttgac
    41881 aggtttcatg taaatcttac cagactcttc aaagactaat tgatgggaga aaatttgcgc
    41941 aatttcaaag agcaagtcat ccgagatttt ctcctcattt tcagagaaaa tccgaccaag
    42001 gccgtcactc tcataacaaa aaccaaagga tttaccagac agattaagcc gaataaaagg
    42061 cttattttct agggtgaaac ttggctcagt attgtaaaga ttcagttcct gactgagttc
    42121 tgcaaaataa tccgtcgcag cctgaggact ttttttctga tagagttctg caaagtaggc
    42181 attaacaaca cttggcggag gtgtaataag tgttaactgc tcctgctctg ttttaccagc
    42241 tagaagctga tccagataga ccttgtccag acttgtataa cctccatact ttagagccaa
    42301 agttttaata tcagtcataa aattcttcta acctccattt atttttctcg gaaatgtagc
    42361 ctgtaatcac ttcgccgtct tcctgataat cacgttcttc cagaattgca acactctcta
    42421 aatcatgaat cttgtaggac tttgaaaaag gcactcgcag ggtaaatgct tcaaaaattt
    42481 ccttaatctt atctagcaat aatgcttgca agttttcacg actgtcctca gacttggcag
    42541 aaatgagggt atatggcgtt tgggtaggcg tgaaatcctc caccaaatcc gctttattat
    42601 aaagcgtcaa gtgaggaata tcttccatgt ccaggtcttt catgatggag agaaccgttt
    42661 tttcatgctc ctcgtggtaa ggattgctag catcgataac atgaaccaga aggtccacat
    42721 gcttgctttc ttccaaggtt gacttgaaac tggacaccaa ctctgtcggc aaatcttgga
    42781 taaagccaac ggtatctgtc aaagttactt ggagattgcc tcccagatga atactcttgg
    42841 ttgtcgcatc cagagtcgca aagagctcat ctgcttcata ctgggtctta ctggtcaaga
    42901 tgttcatgat agttgatttc ccagcattag tataaccaat caaaccaatc ttaaaagtgc
    42961 tagactccaa acgtttttct ctgacagtcg cacgattttt ctcaaccacc ttgagctggc
    43021 gctcgatatc cgtgatttga ttgcgaacgc tacgacggtt cagctccagt tggctttcac
    43081 caggaccacg ggaaccaatt ccccctgcct gacggctgag cataatcccc tgaccaacca
    43141 agcgaggcaa gaggtatttg agttgggcta ggtggacttg gagcttccct tcatggcttc
    43201 gagcccgcat ggcaaagata tccaaaatca actgcatacg gtcaatgacc ttaacaccga
    43261 gaacttcctc tagattgaca ttctgccttg gggtcagacg gttgttgacg atgacagtag
    43321 tgatttcttc tgcatccacc ataagcgcaa tctcttccaa cttaccagag ccgacgaagg
    43381 tcttggaatc atatttttca cgtttttgtc tgtagctatc tacaacgact gcccctgccg
    43441 ttttcgctaa actagccaat tcttccatgg agaggtcaaa actgtccata ccctgcaatt
    43501 ccacaccaat cagcaggact cgctcctctt ttttctccgt ttcaatcatc taaaaactcc
    43561 tctatctggc ttaaaatgcg gtcttgtaca ccagattctc caatctgata aaaggtgacc
    43621 tgcatgcgat tacggaacca ggtcagctga cgcttggcaa aacgacgggt cgcctgttta
    43681 agactctcac gagcttcctc aaaggtctgc tctccacgga aataaggaaa gagttcctta
    43741 tagccaattc ctttagcagc ctgtacatta ggggaatggt caaacagcca cttggcctca
    43801 tccaaaagcc cagcctcaaa catcaaatcc actcggtggt tgatacgctc ataaagttga
    43861 ctacgttcat catccaagca gataatcagc ggttcataca aaatctcttg attttccaaa
    43921 tcctgaccaa aatgggcaat ttctaaggca cgcatagcac gacgacgatt aaactgggga
    43981 atctcaaggc ctgcttgctc caccaaatgg gctaattcct catctgaata tggctccaaa
    44041 ctagctcgat aagctaaaat ctcctcatga ggagtctccc cacctaggtg gtaaccttct
    44101 agcaagctct ggatataaag tccagtccca ccggcgataa tggctagctt gccacggctg
    44161 tgaatatcct caatagtcat cttagcttct gaaacaaaat caaaagccga gtaagactcg
    44221 gttatctctc taacatcgat taaatgatga ggaacagctg cctgctcttc tggactagcc
    44281 ttggccgtcc caatatcaag tcctcgatag acttgttggc tatctccact aaccacttcg
    44341 ccattaaagc actttgcaac ttcaatagct agagccgtct ttccaacagc agtcggtcca
    44401 acaatcacaa ttatttttgt tttcatcttt tttccttgaa aaattcccat tttttcgtta
    44461 ctattattat aacacaaaaa ggtcagtcag aaaaatgtga cctcttgagg aggctggctg
    44521 attgagaata taaaggagga agactcatgg ctaaaggatt cgctaaaggt cttgtaacag
    44581 gtgtcgcagg aactgtcgct gccgttgcag gtgcagtata cgcatttaaa aagaaagtaa
    44641 tcgaaccaga agagcaaaaa gcagctttca tcgaagaaaa ccgtaaaaaa gcagctcgtc
    44701 gccgcgtatc acgttaagaa acaaaagaag ttgggattat tctcaacttc ttttttctat
    44761 tcttttaaat agctaggtca aacttcaact gtggcttaac agggtcataa tccaccaact
    44821 caaaatcttc tgctttgata tcaaagaaat tagtcccatc aggaacattt aaaaccaagc
    44881 gtggttggca gtttgacggc tcccgacgga gcaattcctg agcttgttca aattgattat
    44941 catagatatg gaggttgttg atgaagtaga agaacttccc aaccttccag ccaaaatgtt
    45001 tggcaatcat catctgcaaa gccacatact gcatagcgtt gatgtggtgg gccaccagca
    45061 tatcattgga gcgctgggtc aaggtcgcat ccagatagat ttccccatca acacgccgga
    45121 catcaaacat ggtctgaaag gcgcacggga gcagcccatc tgtttcttcg aaagcttggt
    45181 aatcccagag cgaaataata ttgcggcggt tccaaggatt ggtttccaac tgtttgagaa
    45241 gcttattgat aatgtcgtgt ttcttaacaa cggcaccata gcgctcacca atggttcccg
    45301 tgtctccaac ttcccagtca ttccagtagt gaacattgta cttgtcatta agcacttcta
    45361 agctatttga ctggtcttgg taaatccaga gaacttcttt gatggcggat ttgattgcaa
    45421 tgggacgcaa ggttgtgata ggaaattctc ctttagataa gtcgtactcg gaaaaggcac
    45481 cagttacata cttggaatta gcaacagtcc catccttgta cttaggacga gcctgctctg
    45541 agaaaacacc ttcctttaga atgcgttcaa tattctcttt aaaaatcgta tctgcttttg
    45601 tcatttcgtt tcacctcatt cattgtccta actagtatag cataaaaaat aaaagaggaa
    45661 cattactaac tctaggttag cattttcctc tctcattatc ttattgcaat acaagtgatg
    45721 ctgctccgat aactccagcg tcatttccta gagttgcaag agctaattta gtagatgtgc
    45781 gtacttgtgg gaaactattt tcatcgtaaa ctttttgaac accttgtaga aggaattctc
    45841 ccgcagctga cacaccacca ccgatgacga ttgttgatgg gtttaggatt gaaccaatgt
    45901 tagcacaagc gattcccaag taacgtgaga agttacggta aacaatcaaa gcaaggtcgt
    45961 ctccttcttt tgcgagatca aagacagtct tagcagttac ttcttctccg ttatcaatca
    46021 agcgtttcaa ggctgcatcg ccttcgtatt catcggcata gcgacgagtc aagttgacaa
    46081 tccctgttgc tgaagcaact gtctcaaggc agcctttttt accacaagta catgagattg
    46141 gttggtcaaa gtcaacagtg atatgaccaa gttcacctgc tgcaccagca acaccatgaa
    46201 gcaatttgcc ttctgcgaca ataccaccac caacaccagt accgagtgtc ataaagacaa
    46261 cgtctggttg gttatctcca gcacccatcc agcgctcacc aagagctgct acgttggcat
    46321 cattatcgat gaaaaatgga atgcccaaag ctttttcaat cttttgtttg attggttgaa
    46381 gggttttcca gttcaagttg taggcaccga taacagtccc tttttcacgg tcaaccacac
    46441 ctggtgatcc cattccaata ccttggaagt ccgctgctgc caatccaagc aagtccaaac
    46501 gatgttgaat agactcaatc atatcatcaa cgatatgact tccctcatcc aaaatgttgg
    46561 tcttgattga ccattttcct tggatttctc ctgctgttgt taagattgca aatttgatag
    46621 aagttccacc aaggtcaatc ccaataatct tttgactcat catattctcc tttttcattg
    46681 tgtagtaatt gaaaatgctt acagtactag tatatcaaaa tccattcact tatgcaaagg
    46741 tttgcgtaaa tgaattataa ggaatttttt cgcctaccag tatctgttaa ccatctaaat
    46801 gatcaatggc atattgagct gcatcatttg aaaatttatc aaaatcagaa gttaattgtc
    46861 tatacatacg tttttttgac atgtggaata acgaattata actttttgcc tttcctaaag
    46921 cagcagaata ttcactattg ctatcattac tagaagaagc tgtacttgct tgaccttcct
    46981 tccaaactcc gtcagcgcca acataataac gtccaccatc aacccattca ttgacagcca
    47041 ttttaccatc cgattttaga tagtaatttc cttgccatgt actgtaagca taagaaccat
    47101 ctgatgtcaa ataataccaa gcttgatagg tggcatcata aacccattca cctttagcca
    47161 ttttaccatc tgatttcaaa tagtagtttc cttgccatgc attgcgagca tatgaaccat
    47221 ctgatttcaa gtaataccat gcttggtaag aagaatcata aacccactca ccttgtgcca
    47281 ttttaccgtt tgatttaagg taataagctc cttgccatgt actgtaagca taagaaccat
    47341 ctgatgtcaa ataataccaa gcttgataag aagagtcata aatccattca ctctgtgcca
    47401 ttttaccatc agctttcagg taatagtttc cctgccatgc attttcacta gatttccatt
    47461 tccatcaaaa tagtaccaag aaccgtcctg cttaacccaa ccacttgctg tggatgaagt
    47521 tgtatcagtt tgagttgtag ccgcttgttt tgctttaaaa gcacccttag gagcattttt
    47581 caattcgcaa gccacaccat catgatcgcg gtctaacttg gcagaataac caggttctcc
    47641 ctcatgaaga tccgaatatc cattagccca agcttcctta caactcgaaa aatgaatgtt
    47701 ttcctctgct aacacaggtt gtgaaaacaa ggctaaaatt ggcaacgtca ccagactcat
    47761 ttttaaaaat agacgtttat tcatttcttt ctcccataat tatgatatcg atttcaatat
    47821 tattttatca aacttatttc agcaattcaa ggaaacttct ggtcttttct acaaactcct
    47881 ttggttttgc cttattcaag acatgagggc catctgggat aatctgaaat tgggattctg
    47941 atattagttt atgaagactt ctcatagaac taagattcgg tttatctttg ataccacaaa
    48001 ttagtaaggt tggataaggg caagttcctg ctatatccgt taaatcaagt gtcttcaact
    48061 cctcagaaac tccgaccata agagccttgt ctgctccctg tttttcaaat actcttttgg
    48121 gaagtagttt aaaaatcagc aactgaagat aaaataggat attccctgct aatttaagcg
    48181 ggcatcctga cagaatcaaa gctcgaagat ttggtaaatc gtaactggaa agttctagtg
    48241 ccagggcagc acctaaggac aatccaatca aaacaaaagg ttctgtctct tgagctaggt
    48301 gctgataaac tcgctcctta gcttgttgat agttactaac tccagaagga aataactcga
    48361 tagcctcaga aggataatct gtcagtagat tccgaacttc tttccaagac tctgctgact
    48421 gccctaaccc atgcaaaaat atcagtttca tctagttctc ctcaaggctt agttcataca
    48481 agcctctcac tgcattacag ccgtaaatag cttctgcttg ggctaaatct gccaaggtca
    48541 agactttctc ttctacctgt cctgtttcta gcaaatactg acggtaaatt cctggcaaga
    48601 ttccaagtcg gataggcggt gtgtagagtt ttccagcgat tttcagaacc aaatttccta
    48661 tagaggtttc aagcagtttt cctgacttat tgtggtaaat cttctcttgt tctcctaggc
    48721 tcaaatgcgg tcggtgagtg gttttaaagt aggtaaagga ttgattcaaa gcagcttcct
    48781 gaaggcagac ttgggcctga caaaagcttg tactgagagg ggttaatact tgacgattga
    48841 cttctatctc tccagatttg ctaaggctga ttcgcaagcg gtaatcttga ttagcttcac
    48901 aatcctgaca ctcttcctca atcttgtgtc ccaagtcttc tgcatcaaaa ggaaaggcaa
    48961 aataacgact agcttttctc agtctttcca gatgttgatc ttcaaacagc aggttcttct
    49021 ggctgatttc ccctgtcgta atcagttgga agcgggcttg tttacgataa agaactgctg
    49081 ccttttgatg aacctctcgg tattcagatt cccatgtgct atcccaagta atccctccgc
    49141 caactccata aatggcttga cctttgtgaa gttgaatggt acgaatggcc acattaaaaa
    49201 tccgtcgtcc atttggaagc aagagaccaa tcgttccaca gtagactcca cgcggttgag
    49261 gctccaagtc cttgataatc tccattgtcg caattttcgg tgcacccgtt atggaaccac
    49321 aaggaaagag tgagcggaag atttcaacaa ggtccacatc ctctcgcaac tgactcttga
    49381 tggtcgaagt catctgccaa acagttgaat actgctctac ctggcacaga cgctccacgt
    49441 gctcgctccc aacttcagaa atacggttca tatcattgcg caagaggtcc acaatcatca
    49501 tattttcaga gcgatttttg ggatcctgtt ccaaccaact ggcctgttca agatcttctt
    49561 ggtcagttac cccacgctga gtcgtcccct tcattggtcg tgttgtcaac tcgcgatcat
    49621 tttgctcaaa aaagagctct gggctcatgg aaatcactgc catctcgtca tgttccacat
    49681 aggcattgta gcccgcctcc tgctctacca ccatacgatt gtagatggca aaaggattgg
    49741 cacttaactt ttgcttgagt tggacggtgt agttgacctg ataggtgtct ccctgcctca
    49801 agtgatggtg tatctgggca atggcctttt catagtctgc tgcagacgtc acttcctgcc
    49861 aatttgaggg caaatcaata tcctcataag tcagaggaat aggggaggtc tctaccctat
    49921 catgaacagt aaagtaaagc aggtactctc ccagtagggg atccttgtga actgctaatt
    49981 tttcctcaaa agcaggggca gcctcgtagc tgacataccc caccacataa taaccttgct
    50041 cttggtagct ttccacttgt gccagcaaat ctgccacttc tgctacattt ctcgttttta
    50101 tctctttgat aggctgggta aaggtgtatc tctcccccaa aatcctaaaa tcaatcactg
    50161 tttttctatg cataccttaa gtatagcata aaataagaaa accctcatcc gcaaagcaga
    50221 tgagagattt caattattta aagattgaag ttttaaagct atttgtttgt tgaagaagtt
    50281 tcttataaac tttttctttt acttgcacaa gtttaccatt aactttatta gtaaccatat
    50341 cttcttcaag agctttggca aataatgatt ttaattcatc atagttatga atggtctcac
    50401 catcaatagt aaaaggagta aaaccagcgt tggctttttc taacaattct ttataatatt
    50461 ctttcttaaa atcagcaaac gattggaatc tgccgtcaga tattttttgt ataatatatt
    50521 gatctccaaa ttgtttccct tctttattag cttgagattt taatttatct gaagcatatc
    50581 ctaagaatcc tttatcatag ccataatatc cccagagtct aaatgcatta ttcttaaatg
    50641 taacagcacc gggtgcaccc tcacttgtgt tacctgcata gatactattc atcattttaa
    50701 ttcctacata ggcaatacct ggatcaaata cttctggctt atatatatta ttattcatca
    50761 tacgattagt catcagatta ttatcaacta agtcattaac actgtttaat gttattcctt
    50821 tccaatcatc agagctcata tttcgaacct tgtcatattg atcttttgac cctacagtgc
    50881 gttcaatagg atcaactttc ttaaaccaca gttgatttaa tttatcatca tgtttactaa
    50941 tgactgcatc accttcaaca taatcaagaa gagacaaggt atctatatag cctttcatat
    51001 aattatcaat gtcttctctt gttttaagag tcttcggatc ggtaatatac cactgatttc
    51061 catcatttgg acgatagaaa gtcatattaa ttcccaaagc accgtattca tcaaaccatg
    51121 tacttggtac tggtgtttgt aacattcctt gtgcataggc ttctgcatga gtccctgagc
    51181 gacgtccata tcctcctaaa tagattgcac gatcattaac atgagtagtt tcatgtgtat
    51241 aaacagagat tccaaactca tcaatcatac ttaatgcaat ataatttact tctgttcgcg
    51301 tatccaaagg attatcccaa ataactgcat aagcacctgt tccattgtta ccataatact
    51361 taccaatagg tccaaacaac tctctcaatg gggcatagtc ttctttatta tttctcttac
    51421 catacttatc aggccatcca ccaggtgctt gataaccttc ccaaagagga gttactgtat
    51481 ttttgactag catattctta accttatcta aagataatct ataccaaaaa tcaaaataat
    51541 ttcgataact gtccgctgct ttttcaatct gattttttat tccatcgaag gagctatgcc
    51601 ctaacttttc tgctgttcca acagccattg cactataatt cgagattaaa tacacatgtg
    51661 atttatttag atttaataat gggagtatca tcttccgatg agtagcagat tgtaaattat
    51721 cccaaacttt atatttcgcc gctttaattt catcgacttc cgaagcacgc tccgctatat
    51781 agacattccc ttctgtagct ttcttaaacc aatcataaat atttacatct gcagtaaata
    51841 gtcgacgatt ataatttaaa aagtttacca aattttctga taaggttgtc ttagaaataa
    51901 tctcgctgaa agcatcatat gtccgatgac cttttatatt atcttctctt gaaccgattt
    51961 caattaatct atctaataca cttacatttt taccatagaa atctggtttg aataacatta
    52021 attctttaat gttaacatca ccgaatttaa caccgtagta acggtttaag tatgttaaac
    52081 ctaataatag ggcagcttta tttttctcaa ctttatcaag aatcatttgt tgagctgcag
    52141 atgaattatt cagttgatga tcttcatttt caactaattt agttactaat atgtttaaat
    52201 tagcttttac atggtcaaaa ctttcttcta aataaaggtc tttaattgca tttactctat
    52261 tagaccctgt tctgccaagt ttttggtaaa ttggattaga ttgaagctca atagggctta
    52321 agatatttac gataccgtta attaaagcac tatgatcttt ttgaacgata ttaggtgtat
    52381 atttaatacc taagtcagtt atagtgtatt ctctaacatt acttagacct tcatcactag
    52441 aagataggtt gaagtagtct tttgttccat cagcataatg aacgataatt ttgtttgcat
    52501 cacctaaatc agttacaaag ttattattgt tcataggagt aaccgataga atctctttag
    52561 tatttaactt gttgttctta tctagtttat tagcttgatt aacgataaaa tctttgttat
    52621 agaatggttg tagtttttca atattcttat aagcaagttt atagtctgca ttataatctt
    52681 gaatagactc gtaagctgct tcacgactgc taacattatt caatttgttc aattcataag
    52741 gttcacttac gaatttagca gcagtaatat tgaaactagc aacttttgca tcagcctcag
    52801 atttagataa gtgttttaat ttatttttgt ttttattatc tttaccagtt ccatcttcag
    52861 aagagctata tccaataact ccaaataaat tagacacaaa aggatttgca tctccatcat
    52921 taacatcgtt tgaaccgaat atttcctgac ctttaataac tttcgcatat gttacattat
    52981 cttgaaccgc tccatatggc caagttttag aggttattcc accaacatat ttagtatttt
    53041 taacatcaag aatacctttt gctacagagt ttgtaagttt tccttttgtc cctgatagcc
    53101 agctatgagc tttatattga acgaaaggaa caagcatact tgcatttgcg ttatttgctg
    53161 taatagtagc atcaacgtag gctctattaa caaaccccat atagttagaa ccggcaatac
    53221 ctccaactgt tgaattatta ccagcagaat ttatactacc gataaatgcc acattttcta
    53281 aagtagcgtc ttcttttatg ttatttacga acccagcaac attatttcta gctgttatgg
    53341 ttccgattgc tttgatattt tctatacgtg tcgttccact gatttcattt gctattgcag
    53401 cgatattatc ttgattagat aaatcaatat caatattttc aaaatttata tttttaacag
    53461 ttccagcctt aatcttatcg aataaaggat gttccaaatt atggatagca tagcgtttat
    53521 caccatcact caatagttta ccagtaaact ctgaagtaat ataagatttc cctttaggaa
    53581 caacgttacg agcgctcatg ctttgaccca gtttaaattc accggcagga tttgtctgaa
    53641 tggcttggat caattcttca aagtcgtaga aaataccagc ctgactagct ttgggttttt
    53701 caatatagta ggtataagtt tcttcaaagc gattatcgac attacgttgg accaagttat
    53761 ccgctactgc tattaccttg tagacttgtt ttccatcaat tgttgactct tcaatttttt
    53821 gaaccgctag tagattggtc ttatggtcat tagaggtaac ttttaaataa taatttgaca
    53881 aatcagttgg cactgaagtc aatcgagttt catcagtttc aacttggttt tcatatttga
    53941 ttaaatccgt tcttataata tcttttattt caactttttt gagatcaatt cttagcggtt
    54001 cttctttcag aacttcttcc tcatccccct caccacggtc ataaaccatc tttgtttcaa
    54061 gtttataatc cttgtagtac tgcaaatctg tcagggtagt tgtcaagtct tctggtgaaa
    54121 cattcaaggt tttgacaatc tcatcacctt ttttcagagt tagggtaata gatttaatgg
    54181 ctgccttact tggattttct aaactatact taacatctga agtacgcttc aaatccttag
    54241 attcaatttc tgtgatggtc aacactggtt tttcaaagct cttggtacca cgtttcaaaa
    54301 ttttgtcttg aggttcctca aggatttcct ctgtaacttt tggagcgtct tctgttttaa
    54361 ctcccttaat ggtattaaag gtcttggtga tttttttctg gccttctttt ccttcttgag
    54421 ctacaacttc taagcctttt ttcagttggt catcttcttt aacaacttcc ttaaatggaa
    54481 tcttttcaag actttcttct ataagagttc cttcaattgg ttttgtacca cggattacct
    54541 gttgatttac aggctccttg gtcacttccg tactggttga aagaacttgg tcagttttaa
    54601 caccttctac tgttttatag gttgtttttg taacttgact tcctttttca ccagttcgta
    54661 ggacagtttc ttcgtccgta tacttggttg gatcctcagt cgtttcagtt ttgtagtcta
    54721 ggtctgtagt cgatgtttca acaagggttc cctcagttac tttgtactca ggtaattgtt
    54781 cttgagcaag agcctcaccc acgtgacctt tttcttgcgt acctttagct gttttagtct
    54841 cctcttttga ttctactggt tcttcaacct tgatttctgg ggcttctgct ggctgttcat
    54901 cttcttgttt cggtgtctct tccgctcccc tatcttcttt aggattttct tgttgtgatg
    54961 attcttttgg tgtacttggt tgctcagctt gtgtaggttg cacgggttgt tctgggactt
    55021 ttgcttgttc tactggtggt tcaacttttg attcctcagc tggtttgtct gatggttgac
    55081 tttctggctt aactgctact ttttcctctg gttttgactc aacttctcca cctacttctt
    55141 caactggagc tggttctgct gaatcttctt tcccctcttc tactttagga agggtgtcgt
    55201 cagtaggttt tacctccgat tttggttctt cctttggact ttcttctgtt ttaggtgctt
    55261 cttcttttgg agcttcctct gtctctacta cttggttttc tgtcctagct tgctcctgat
    55321 ttgttgttga ttgaggagtc tcaacttcga ctacagtcac ctctccaggt tttgctgagg
    55381 tttcttctaa aacagtgtcc aagccaagcg ttttgaggat gtcacctgat agataaccaa
    55441 catagcgata gccatccatt tcaacaacac cctctcgact agccagcgct agggtcgcaa
    55501 ctgggtctac agcccctgca ctaggaagaa ctaccaatcc catagctcca actagaaaga
    55561 cgctagcaat tttctttctc ttgtagatta aaagcaagct cccaacagtc agcaaaccaa
    55621 aagctgtcaa aacagatgct tctgtccctg tttgaggaaa ctgatctttt tgatacacca
    55681 aaccatatac aacttcattc ctgtcaggct ttcctgtctg aattaaatct ttagcttctt
    55741 gtgaaataat ctctttattt acatagtgat aggtggctgc gtccactaca gaaggagcca
    55801 tcaaaaggct tccaagaaat acagagccta caactccctt aatcttacga attgaaaaac
    55861 ggtctttttt aaacactttt atctccttta ttcattctca agactttcta atagcatctt
    55921 gcggatagtg cgcacgcgca cctccgatta attttggacg actagccagt gccgttacat
    55981 gggcatgacc aatctctctc aaaatagggc gaatcggaac ctgaacatgc ttgacatgca
    56041 tgccaattgc agtgtctccg atatccaatc cagcatgagc cttgataaat tcaacctcaa
    56101 ctggatcctg cataaactta aaggctgcca actgccccga acctcctgca tgaagagtag
    56161 gatggacact gacaatttcc agatcaaact gctctgccac ctgacgttca acaacgagag
    56221 cccgattgac atgctcacaa ccttgaactg ctaaatggat acctctacta cctagaatac
    56281 ccaagatagt ctccactatc agctcaccaa tctcttgact ggattctttc ccaatctgac
    56341 cacctagcac ctcactagaa gatagaccta aaacaaaaag gaccccctgc ttcaaattgg
    56401 tcttttctaa aacatcttcc actacctgac gtgtttctct ttgaatctgt gtctcgttca
    56461 tctctgttac ctctgttgtt actcttctat cataccgttt tttcttgttt ttagcaagat
    56521 agacaaccta gaaagcttgc ccaattacgc ataaaactcc cagaattgac tgggagttag
    56581 ctagtttcta ttctatttat atatatttca actttcgtcc ctttttgggg tctagaatca
    56641 atcttcatct ggtaattggc tccaaaatga agtttgagcc gttgatcgac attttgaaga
    56701 ccaactcccc cacgtttgag ttgactttga ctactatcac cagcatcttg gaagccaacg
    56761 ccatcatcct caatacggat gaccaatccc gaatcctgtt tctggacaga aagtttaata
    56821 tggccctgac cttccttttc cttaatgcca tggtaaagag cattttctac aaggggttgt
    56881 aggaccagct tgggtaagac taaattatca aaggcaacat tttcattaat ttcgtattcc
    56941 agcttatctc catagcgttg tttctggata aagagatact ggcggacatg attgatttcg
    57001 tcagagagac aaatcaagtc tttgccttga ttgagcgcca agcggaaata ggttgccaag
    57061 gacttggtca cctgcaccac tcgctgacta tcatgaaatt cagccatcca gatgatggtg
    57121 tccaaagtgt tatagaggaa atgtggatta atctggctcg aaagggcttg aagttggtac
    57181 tgacgggtcg tttcttcctg gctacgaata gctaccatca actgatcaat ctgatccaac
    57241 atggcattaa attggcgagt tacttctctc agttcatagg caccaacttc cttggcacga
    57301 agattttgag caccagaagc aatttccaac atggtttctc tcaaatcctt caaaggagca
    57361 atccagcgtt taagactgaa ccacactaag cagagacaaa caagaagaga tgtgacactg
    57421 gccccaagca aggtccacaa gagctgactc cgaacctggt ctaacttttc caatgatgac
    57481 acgccaagta ccgtccaatc agttcctgca atcttctctt gactgacgta ggatttgtga
    57541 ccaggagtat aaccctgacc tgtctcgatg tagggtttca tagcctccat tttgctagac
    57601 gaactataaa ctgtgtgttg aggatggtag acaaattcat ggttttcatt gataatgaag
    57661 gcaaagccct gctgccccaa ctggagttga ttgagatagg cttccagagt ttcataagaa
    57721 atatccaaac gaagcacacc aagattggct ccctttgcat caacaagttc ttgagtgaca
    57781 gaaatgaccc actgactatc tgatttacga gctggagtca aaacaggcat agctccctga
    57841 tgaatagcct tttggtacca atcctcagcc atcatatcag aggaagtttt catctgcaca
    57901 ctgtcatctg tagaaatgac ctgaccagat ttggtcacca gcacaacagt tttcaagtcc
    57961 ttatctgact tcaagatggt caaaaacaaa tctcggattc cctcgacctt gtcttgactg
    58021 ggattctcag cataggccag aacatccgtc tgctgggtca aaccagtcga ggtggtttct
    58081 agttttttga tataagactg aataaagtgg ctagtctggc tgatggtcgt ttggctgttg
    58141 ccctcaatgg tggcctcaat ggctgaagaa cttgattgat agtagaaagt tccaaccaga
    58201 gctaggagaa tgagaaagac cagaaagatg gaaataacca ttctaactaa aagagaagaa
    58261 cgcttcatcg gtcttctccc ttcttaaact gacgaggtgt cacacctgca atctgcttaa
    58321 aacgttgggt aaaatagttc atatcttcaa aaccaacctt ctctgcgatc tcataaatct
    58381 tcagatctgt agttaaaagc aagagcttgg cttgtttaac acgttctctc accagataat
    58441 cctgaaaagg caagcccaac tctttcttaa tcaaggaact cagataggtc ggactaaaac
    58501 ctaagtcact ggctaaagac tttaaactaa attggctatc agccagatga gactggattt
    58561 tctgggccat gtttccttca aacctattag tcaataaatc ttgtaactgc tcttctttct
    58621 cttccttgtc tagtttttgt ttgattttcc ccaacatttc ctcaatatcc tgacgagaaa
    58681 agggtttgag caggtagtcg tccacaccta gtttgacagc agacaaggca taatcaaaat
    58741 catcgtaacc tgttaaaaag accaaatgaa cctgaggata ggtttctcgt accagactgg
    58801 ccaactggat gccatttaga tgaggcatgt tgatatcggt taaaatgata tctggcacct
    58861 gcttttggat caattcccaa gcctgccttc cattttcagc ctgaccgatg atttccatat
    58921 cgtaggctgc tacattgacc agtttagtca aaccttgtct taccagatat tcatcttcta
    58981 cgattaagat tgtgtaggtc atgctctgct cctttaccac ttactagtat cagtatagca
    59041 aaattctcct ctaactgctt aggaaagacc tcttatactc aataaaaatc aaaaagtaaa
    59101 ctaggaagat agccacaggt ttctcaaagt atagctttga ggttgta
//
LOCUS       DAVBOM010000007        58917 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBOM010000007 DAVBOM010000000
VERSION     DAVBOM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58917
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.007"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(181..1359)
                     /locus_tag="VQ878_000399"
     CDS             complement(181..1359)
                     /locus_tag="VQ878_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3094808.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            1639..2901
                     /locus_tag="VQ878_000400"
     CDS             1639..2901
                     /locus_tag="VQ878_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3094809.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWSVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDSGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            2904..3800
                     /locus_tag="VQ878_000401"
     CDS             2904..3800
                     /locus_tag="VQ878_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET3094810.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            3815..4132
                     /locus_tag="VQ878_000402"
     CDS             3815..4132
                     /locus_tag="VQ878_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3094811.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            4149..4465
                     /locus_tag="VQ878_000403"
                     /pseudo
     CDS             4149..4465
                     /locus_tag="VQ878_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
     gene            4475..5077
                     /locus_tag="VQ878_000404"
     CDS             4475..5077
                     /locus_tag="VQ878_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3094812.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            4983..5609
                     /locus_tag="VQ878_000405"
                     /pseudo
     CDS             4983..5609
                     /locus_tag="VQ878_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            5624..6394
                     /locus_tag="VQ878_000406"
     CDS             5624..6394
                     /locus_tag="VQ878_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET3094813.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(6672..6959)
                     /locus_tag="VQ878_000407"
     CDS             complement(6672..6959)
                     /locus_tag="VQ878_000407"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3094814.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            7163..7435
                     /locus_tag="VQ878_000408"
                     /pseudo
     CDS             7163..7435
                     /locus_tag="VQ878_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7545..7760)
                     /locus_tag="VQ878_000409"
     CDS             complement(7545..7760)
                     /locus_tag="VQ878_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3094815.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGAVEGVKNMLSGDDK"
     gene            complement(7791..8399)
                     /locus_tag="VQ878_000410"
     CDS             complement(7791..8399)
                     /locus_tag="VQ878_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3094816.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(8438..8608)
                     /locus_tag="VQ878_000411"
     CDS             complement(8438..8608)
                     /locus_tag="VQ878_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET3094817.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(8620..9186)
                     /gene="amaP"
                     /locus_tag="VQ878_000412"
     CDS             complement(8620..9186)
                     /gene="amaP"
                     /locus_tag="VQ878_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET3094818.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(9270..9434)
                     /locus_tag="VQ878_000413"
     CDS             complement(9270..9434)
                     /locus_tag="VQ878_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3094819.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIIGAAIVI
                     TVVSFFTGRK"
     gene            9877..11358
                     /locus_tag="VQ878_000414"
     CDS             9877..11358
                     /locus_tag="VQ878_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3094820.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            11720..12715
                     /locus_tag="VQ878_000415"
     CDS             11720..12715
                     /locus_tag="VQ878_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3094821.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            12842..14152
                     /locus_tag="VQ878_000416"
     CDS             12842..14152
                     /locus_tag="VQ878_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3094822.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            14248..15150
                     /locus_tag="VQ878_000417"
     CDS             14248..15150
                     /locus_tag="VQ878_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3094823.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMINLVQRRVLKEDD"
     gene            15152..15997
                     /locus_tag="VQ878_000418"
     CDS             15152..15997
                     /locus_tag="VQ878_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3094824.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            16007..17326
                     /locus_tag="VQ878_000419"
     CDS             16007..17326
                     /locus_tag="VQ878_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3094825.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17536..17608)
                     /locus_tag="VQ878_000420"
     tRNA            complement(17536..17608)
                     /locus_tag="VQ878_000420"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17573..17575),aa:Lys,seq:ctt)
     gene            complement(17873..19144)
                     /locus_tag="VQ878_000421"
     CDS             complement(17873..19144)
                     /locus_tag="VQ878_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET3094826.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            19414..19653
                     /locus_tag="VQ878_000422"
     CDS             19414..19653
                     /locus_tag="VQ878_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094827.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            19818..19997
                     /locus_tag="VQ878_000423"
     CDS             19818..19997
                     /locus_tag="VQ878_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094828.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            20134..20312
                     /locus_tag="VQ878_000424"
                     /pseudo
     CDS             20134..20312
                     /locus_tag="VQ878_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            20349..20801
                     /locus_tag="VQ878_000425"
     CDS             20349..20801
                     /locus_tag="VQ878_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET3094829.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            21092..21562
                     /locus_tag="VQ878_000426"
     CDS             21092..21562
                     /locus_tag="VQ878_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET3094830.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            21581..22669
                     /locus_tag="VQ878_000427"
     CDS             21581..22669
                     /locus_tag="VQ878_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET3094831.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            22650..23078
                     /locus_tag="VQ878_000428"
     CDS             22650..23078
                     /locus_tag="VQ878_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3094832.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            23213..24166
                     /locus_tag="VQ878_000429"
     CDS             23213..24166
                     /locus_tag="VQ878_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET3094833.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            24168..24911
                     /locus_tag="VQ878_000430"
     CDS             24168..24911
                     /locus_tag="VQ878_000430"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET3094834.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            24922..26718
                     /gene="pepF"
                     /locus_tag="VQ878_000431"
     CDS             24922..26718
                     /gene="pepF"
                     /locus_tag="VQ878_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3094835.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(26778..27455)
                     /locus_tag="VQ878_000432"
     CDS             complement(26778..27455)
                     /locus_tag="VQ878_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3094836.1"
                     /translation="MKPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            27702..28472
                     /locus_tag="VQ878_000433"
     CDS             27702..28472
                     /locus_tag="VQ878_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094837.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            28465..29229
                     /locus_tag="VQ878_000434"
     CDS             28465..29229
                     /locus_tag="VQ878_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3094838.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            29653..30444
                     /locus_tag="VQ878_000435"
     CDS             29653..30444
                     /locus_tag="VQ878_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET3094839.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALVYANLLSVDANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            30555..31223
                     /locus_tag="VQ878_000436"
     CDS             30555..31223
                     /locus_tag="VQ878_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET3094840.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(31477..32010)
                     /gene="queF"
                     /locus_tag="VQ878_000437"
     CDS             complement(31477..32010)
                     /gene="queF"
                     /locus_tag="VQ878_000437"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET3094841.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(32315..32629)
                     /gene="trxA"
                     /locus_tag="VQ878_000438"
     CDS             complement(32315..32629)
                     /gene="trxA"
                     /locus_tag="VQ878_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3094842.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(32646..32867)
                     /locus_tag="VQ878_000439"
     CDS             complement(32646..32867)
                     /locus_tag="VQ878_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3094843.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(32966..33346)
                     /locus_tag="VQ878_000440"
     CDS             complement(32966..33346)
                     /locus_tag="VQ878_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3094844.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(33489..34442)
                     /locus_tag="VQ878_000441"
     CDS             complement(33489..34442)
                     /locus_tag="VQ878_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3094845.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(34510..35718)
                     /gene="sstT"
                     /locus_tag="VQ878_000442"
                     /pseudo
     CDS             complement(34510..35718)
                     /gene="sstT"
                     /locus_tag="VQ878_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            35857..36417
                     /locus_tag="VQ878_000443"
     CDS             35857..36417
                     /locus_tag="VQ878_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET3094846.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            36474..37382
                     /locus_tag="VQ878_000444"
     CDS             36474..37382
                     /locus_tag="VQ878_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3094847.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            37334..37924
                     /locus_tag="VQ878_000445"
     CDS             37334..37924
                     /locus_tag="VQ878_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET3094848.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            37927..39033
                     /gene="yqeH"
                     /locus_tag="VQ878_000446"
     CDS             37927..39033
                     /gene="yqeH"
                     /locus_tag="VQ878_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET3094849.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKFEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            39247..39558
                     /gene="yhbY"
                     /locus_tag="VQ878_000447"
     CDS             39247..39558
                     /gene="yhbY"
                     /locus_tag="VQ878_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET3094850.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            39610..40239
                     /locus_tag="VQ878_000448"
     CDS             39610..40239
                     /locus_tag="VQ878_000448"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET3094851.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            40239..40832
                     /gene="yqeK"
                     /locus_tag="VQ878_000449"
     CDS             40239..40832
                     /gene="yqeK"
                     /locus_tag="VQ878_000449"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET3094852.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            40833..41333
                     /locus_tag="VQ878_000450"
     CDS             40833..41333
                     /locus_tag="VQ878_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3094853.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEECFADVL
                     DYKHIF"
     gene            41346..41699
                     /gene="rsfS"
                     /locus_tag="VQ878_000451"
     CDS             41346..41699
                     /gene="rsfS"
                     /locus_tag="VQ878_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET3094854.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHIEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            41802..42548
                     /locus_tag="VQ878_000452"
     CDS             41802..42548
                     /locus_tag="VQ878_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3094855.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            42558..43655
                     /locus_tag="VQ878_000453"
     CDS             42558..43655
                     /locus_tag="VQ878_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3094856.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            44002..46749
                     /locus_tag="VQ878_000454"
     CDS             44002..46749
                     /locus_tag="VQ878_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HET3094857.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVKL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            47092..48705
                     /locus_tag="VQ878_000455"
     CDS             47092..48705
                     /locus_tag="VQ878_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET3094858.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            48835..49461
                     /gene="gmk"
                     /locus_tag="VQ878_000456"
     CDS             48835..49461
                     /gene="gmk"
                     /locus_tag="VQ878_000456"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET3094859.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            49486..49800
                     /locus_tag="VQ878_000457"
     CDS             49486..49800
                     /locus_tag="VQ878_000457"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET3094860.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            49866..52262
                     /locus_tag="VQ878_000458"
     CDS             49866..52262
                     /locus_tag="VQ878_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET3094861.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKTMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARIFRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            52275..53210
                     /locus_tag="VQ878_000459"
     CDS             52275..53210
                     /locus_tag="VQ878_000459"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET3094862.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            53203..54516
                     /gene="rsmB"
                     /locus_tag="VQ878_000460"
     CDS             53203..54516
                     /gene="rsmB"
                     /locus_tag="VQ878_000460"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET3094863.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSVYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANSSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            54531..55271
                     /locus_tag="VQ878_000461"
     CDS             54531..55271
                     /locus_tag="VQ878_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET3094864.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            55268..57247
                     /gene="pknB"
                     /locus_tag="VQ878_000462"
     CDS             55268..57247
                     /gene="pknB"
                     /locus_tag="VQ878_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET3094865.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            57362..58120
                     /locus_tag="VQ878_000463"
     CDS             57362..58120
                     /locus_tag="VQ878_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3094866.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLVN"
     gene            58122..58571
                     /locus_tag="VQ878_000464"
     CDS             58122..58571
                     /locus_tag="VQ878_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3094867.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            58633..58917
                     /locus_tag="VQ878_000465"
                     /pseudo
     CDS             58633..58917
                     /locus_tag="VQ878_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT        18011 a        10263 c        12756 g        17887 t
ORIGIN      
        1 gatcgattcg tcctgttatt atttcatttc actatacatt atgaaaaagg ggagatagga
       61 gtataattcc aaatataaag aaagcgaaca aaacagaatt ctgattttca gaaaacaggt
      121 ttattcgctt tttatgatat actccctctt tttagcctat ttattaaatg taatagaaaa
      181 ttaagaatgt agaattgtat gatacaaaca aagtgcaata gctgagtgtg cggctgtaaa
      241 atcattgtaa ggttcaataa tgacttcagg taggcgatta tagagcagtt tgggtttgta
      301 gttcatttca ctatatagtt tttggatgat gtgttgattt gttagtaaag gactatgtag
      361 gtagattttt tgagagtcaa tcatcatact gatatttaaa atggtttgac taagatagag
      421 taaggcttga tggataagtg tgattattcc agtgtcacct aattgataag cggttaaaat
      481 aacttggata tcaatatcat cggcattttt gactaaacta ggaagtagag aatagggaga
      541 ttgatgatat agaatttttg attttttgat taaccaagat tctccagcaa aagtttgtaa
      601 gcatcccttg cgcccgcagc tacattcttc tccctcagat gaaacaactg tatgccctat
      661 ttctccaatc attagatttc ctttcccata aatgtttccg tcgtagatat aagaacagtg
      721 catacctcta gcaaaatgaa aataagcaaa attagggtca ttctgttggc gactaaatag
      781 gcgtttacct atagccatac agttaacatt gttagagaaa aacaaaggct tatcaaagtg
      841 ggattgaatc atttctaagt cgatatgttg ccataaagga ttgtttgttg ttattttata
      901 atcatctaaa tagcgaccag gtagcgcgat tccaattgct tctatttcat aatcagagca
      961 gttatttaag aattgcttta gtgtctggtt aatgagttga tttccctttt cttggattaa
     1021 ctgtttagta acaatttctt tctcttcctt taagatattt cctagattat ctcctaaagc
     1081 aaaagtgaaa tgtttttcag atagttcaca accaatgtag taaaatcgtt tagcttgaat
     1141 gtctagcagg attttttttc tccctacgct tgtatcgtgt tcgtcttcac caagttctaa
     1201 gagaatattt tctttaatca gatcatttgt gatactgcta gttgttgcag gtgttattcc
     1261 tgttttagta gcgatttcaa ttcgtgaaat gggacctaat gtgtaaactg tttccagtat
     1321 tttagctctt agttgtaatt gtttcttaga taaggtcata ttagttttct tcctagttgt
     1381 cagattctta aaatcctatg attttttgct atggataaat gtagatgtta atctttttaa
     1441 gcttttcatt acttactggt ctctttttat tatatattga taataaaaaa taatcaaatg
     1501 tttacacaaa tccttgacaa ggctttctta tagttgtaaa atataaataa caaaagataa
     1561 tcaaataaca acttgacgtc aaaaaataaa gataattgat aacttttgat aataaaatat
     1621 atttaagagg aaaaggttat ggaaaaatta ttacaagaaa agttacttcc agtagcggct
     1681 agattgggta ataataaagc gttggtttct attcgagacg gtattactct aactatacct
     1741 ttattgttga taggttcatt actaatggtt attgcaagtt ttcctattcc aggatgggaa
     1801 aaatatctgg gtgatattgg tgttgctgac tatttatgga agggtgttga tagtagtttt
     1861 ggattacttg gtcttgtagc tagttttggt atcgcttact ttatggctag acaatacaaa
     1921 gttgatggta ttcctgctgg tattgtgtca ttatcatctt ttattacagt tacgcctttc
     1981 attagaggag aggctggagc aggaatgcct accgctttca tggcatcaaa aggtttattt
     2041 gttgctatga ttttaggatt gattaatggc tatatctacc aatggtttat aaatcataat
     2101 atacagataa aaatgccgga tggtgttcca ccagcagtat ctaaaagctt tagtgccatt
     2161 attcctggtg cagtgactat tgttggttgg ttgattgttt atgcaacttt agataaatta
     2221 agtttaccta atcttcatga aattgctcaa gtagctttgg gaggtccact tggactttta
     2281 ggaaataatg ttattggtct tcttatctta attttcctta atagtagttt ttggtctgta
     2341 ggattacacg gaggaaatgt tgttaatgca gttatgaaac cgttatggtt agctaatcta
     2401 gatgcaaata aagtagctta tcaaactgga gaaactcttc caaatatttt tactagcgta
     2461 tttatggata attttgtatt cataggtggc ggtggtgcaa ccataggttt agttcttgcg
     2521 ttaggatatt tagcacataa gaagaaagct agtaaacaac taaaaacttt ggcacctata
     2581 actgttatac ctggattatt taatataaat gaaccagcaa tgtttggcgt tcctattgtt
     2641 ttgaacattt tgttactagt tccatttatc ttagctccaa tgtttaactt actagtagcg
     2701 tggggagcaa tggcatcagg tttggttccg ctaacttata cagattcagg ttggactatg
     2761 ccacctgtta taagtggttt acttgctaca ggaagtattt ctggttcatt attacaaatt
     2821 gtattgattg ttttggatgt cttactttat ttaccatttg taatagctat tgaaaaacgg
     2881 tttaagttat tggaggattg agaatgaaac gtttaattag tgcaaatcca tctgagatat
     2941 tacagatgaa tgctgaagaa ttaaaacaaa gtattttagc aagtgaaggt agagttgttc
     3001 tatctgaaaa tgtagttact cgtgagacat ttgttgggga tataactaat tctgaaattg
     3061 ctagagcttt tggagctgat atgattttat tgaattgtgt tgatgttttt gagcctaaaa
     3121 tttatgcttt ggatagttca ggtgatgatg ttattcatcg cttacaccag cttgttgctt
     3181 gtccaattgg tgtaaatttg gaaccgattg acccatctgc aaagatgcta gaggaaacac
     3241 aggaaattgt tgcaggtcgt gttgctagtg ttgaaacatt gaatcgaata gaggagttag
     3301 gttttgactt tgtctgtttg actggaaatc ctggaacagg agttagcaat cgagaaatca
     3361 ttaaggctgt tcaaactgct aaggaaaact tttctggttt gattattgca ggtaagatgc
     3421 acggggcagg agtgaatgag cctgtggcag agctttctgt cgcagagcaa ttgttggaag
     3481 caggtgcgga tgtgatactt gttccagcag ttggaaccgt tccagccttt catgaccaag
     3541 agttgcgtga agtcgttgat ctcgttcata gtaagggtgg tcttgtattg agtgctattg
     3601 gtactagcca agaaacatct gatacagata ctattaagga aattgcactt agaaataaaa
     3661 tttgtggagt tgatattcaa catataggtg acgcaggata tgggggactg gcaacagtcg
     3721 ataatattta tgcattgagc aaggcaatta gaggagtgag acatacagta tctcgcttgg
     3781 ctaggtcagt aaataggtga taaaggagta agctatggct aaagtaacaa ttatgttagc
     3841 atgtgcagca ggtatgagta caagtctgct agtgacaaag atgcaaaagg cagcagaaga
     3901 taaggggttg gatgcagaaa tttttgcagt tccagctcct gaagcagaag aaattgtagc
     3961 aacaaaagaa gtaaatgtgt tgcttttagg cccccaagtt cgctatttac taggggactt
     4021 tcaagaaaaa ctaaaagata gacagattcc tgtggcggtt attccgatga cagattacgg
     4081 aatgatgaat ggttctaaag ttttagattt agctgaaagt ttattagact aagattgagg
     4141 agaatgttat ggatgaaagt aatttagaat ctgtaatggg gctaattatg tatggtggag
     4201 atgccaaaag taatgctatg gaggctattc aggcagcaaa aaaagggatt tctctaaagc
     4261 caatcgaaga ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga
     4321 aatgttgaca agagaggcac aggggggaaa aacatcaatt agcctcttga tggtacacgc
     4381 gcaagatcat ttaatgacga gtctgacttt tgttgacttg gcgaaagaag tggtagaagt
     4441 atacgaacga tttgaaaaaa attaggagtt tggtatgaat acaatgttgg ataaaatgca
     4501 agaaaaactt tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg
     4561 tgattcattt gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa
     4621 tgcttttcta gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca
     4681 gtggcttgtt gacatcaata atttggtatt caagggaagt ataccaattg tttccttgtt
     4741 gttcatctat tgcttgggag tgaatatcgc taagatttac aaggttgata cagtttctgc
     4801 tggtttggta tcacttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt
     4861 ccctttggca aatgtaggag atgtgaaatt agatcagatc ttacaaggaa ttgataatct
     4921 agcatttgat ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat
     4981 taatgccaga ggcagaaagg gagggatatc ctcatcctgc tggggctccg tggtggttac
     5041 aagttccgaa cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag
     5101 aagaccatcc agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg
     5161 gaatgtcttt accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg
     5221 aatatccttg gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag
     5281 gaagatttcc ttatgaaaat actgtctcag atggatttat aggaacggct cctgtctatg
     5341 aatttttacc taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc
     5401 gcaatccgag atatacctta ttagctagtt ttaatgaaga tgactatgag ttgccaaaat
     5461 atgggataca agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt
     5521 attgtaatcg ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc
     5581 atctaggttt tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta
     5641 ttttctaatc attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat
     5701 tataattaag ccacttatgg atagttttgg gtaccattcg gtcagtgata ttgcttttta
     5761 ttctagtttc tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag
     5821 taaagagata aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt
     5881 tctaggtcat cttatttttc aagttttgtt atctcaatta tcagtacggc tagtatccat
     5941 tgttcaaatg attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa
     6001 aaaaacttat caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt
     6061 aatttctagt tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt
     6121 tttttctatt tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca
     6181 gctgtctcat ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc
     6241 tgttccagtt atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa
     6301 agtcttacct gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg
     6361 aatgacttta tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga
     6421 cttcctgtaa aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac
     6481 caactcagaa aatatctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt
     6541 tcttgaggct gggaaaaagt ctttaaaatt aaaaaatgca taatatcagg tgttggaaaa
     6601 actttgatac tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt
     6661 ttttgtccag cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca
     6721 tgacacctta aaagtctatt tgaatgttcg ttgagacacc gctgtcttga acatcctaga
     6781 ttcgcaaaaa agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct
     6841 tttccacagt caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct
     6901 tggatggatt ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat
     6961 tgactatacc tgttcgctca caaataggag agaactgttt acgaaaatct aatgaatatg
     7021 ccacaagaac attataccgc aacgtgtact atttttggtt cattttacta tagaaactat
     7081 tgaagaacct gtacgaaaat atatcatgaa aaagggtaga tagaaagcaa acagccttga
     7141 aatcaatgtt gactgcgatt atgaacctga atcagcccct caaaagggac tgtatatgaa
     7201 tgaacgttac cagtgtttaa aaactaaaga atatcaggca cttttatctt ccaagggtag
     7261 acaaattttc gctaaacgta agattgatat gaaatctgtc tttgggcaga taaaggtttg
     7321 tttgggttat aagagatgtc atctgagagg gaagcgtcaa gtgagaattg acatgggatt
     7381 cgtactcatg gccaacaacc tgctgaaata taataagaga aagaggcaaa attaaaaagc
     7441 tagagttccg caattgggaa tccctagctt tttgttttct gagaatcatc ttgactcaga
     7501 ctcttttgac taatgttact aaaaagataa agtaactttt aaccttattt atcgtcgcca
     7561 ctcaacatgt ttttaacacc ttctacagca ccttctacag caccttctac agcgtctttg
     7621 gcatcttcgg cgacttcttt tactttagaa acaacttttt cagctgctcc ttctttttcc
     7681 attttttcat caccgatggc tttcccaaca ccttctttaa tagaaccttt agcttgattt
     7741 aatttttctt ctactgacat gataatttct cctgttatat ttattttatc ttagtttaca
     7801 cgagtgtttt cgtgagatac tacaccattt gctgcacctt taacagcttc tacaccttcg
     7861 ctaacttttt cttgaacagt tgagaaacca gatccaagac cagatttagc tttttcgaat
     7921 tgttctgaag tgaattctcc tgttgattca gcaacgtcag atacgcgatc ttgaaggctt
     7981 actgagtctg cttcatgctg ttctttagtt ttgatgtcga caacgtttac gttgatttca
     8041 acaatttcca agtcagtcat tttagcaact tctgaagata cgatttctct gatttctgaa
     8101 tataaagctg gaacattttt ttggtactca acaataacgt ttaagtcaac tgcaacttgt
     8161 gttttaccaa cttctacgtt aacaccactt gttacgtcat cgctgttaac gattttttct
     8221 ttaagatttg agaagaaacc accatcgatt cccaaaagac ctgaaacgtt ttctagtgaa
     8281 agaccaatga ttttttggat aactttatct tcgtaagtaa gttccccttt gatttcgtga
     8341 gctacaacag tagcatcttt cttttctacg ttagtgtttg tgtttttttc gtttgacata
     8401 tgaaactcct ttaattaaat tagtaatttt tattttttta tttatctata tagttttttt
     8461 cgatatataa tccagctgca actcccagtg ctcctaaaat caatacaaat attgttttga
     8521 agaagccaaa ggagacaatc aaacaagcca gaaatacgcc tatgagacca gcgataattg
     8581 gatatcgata ttgtttaagc cattccattt tttacttcct tacttcacac gactaacagt
     8641 ctttttgttt tgaggttttg gttggtaatt ttttactgca acttcaagtt ttacttgacg
     8701 ctcaatacca aaaaactgct tcaatccatt agttatttca ttttgaatta tttggcatct
     8761 gtcagcgatg ttgtctgaag gaagaatttt accttctaca tgaacgaaac atttattttt
     8821 tcgtaaattt acatgaacag ttgggttctt gatcaatcta tgatcactca ccaaacttct
     8881 aacaaaacct tcgattgccg aattctttaa ttttaatgta tcgtttttag tttcaagttg
     8941 gatttccaag taacgtttag gataaaacat cacaactaaa atggataata aaactaaagt
     9001 tgatagaacc actgtccccc aaaagacata tctagcaaga tagaattcaa ctacggagtt
     9061 ctgtctccag ctaagtagat gaatacctag atcactaact tgatgataat ctatcaaaac
     9121 aggaaggaaa attgtcaaga ttaaaataca gaaaataatg aaacatattt tctttgcttt
     9181 tgacatatac aatcctttcg atttaacatt taaactattt ttcccgtcat tgatttaaaa
     9241 atagtttgct aactttactg gcgaaaagtt tactttctac ctgtaaagaa tgacactaca
     9301 gtaatcacaa tcgctgcacc tataatagat gggagcaaag ccattccagc gattgatgga
     9361 ccccaactac ctaaaagaga ttgtcctgca tatgccccga ctaaaccagc gaatacattt
     9421 gcgatgattc ccatagaact acttttttag tgattttacc tgccaagaga ccaataagac
     9481 ctccagcaat aattgatcac aacactgcct accctccttt tttattttaa tatcaaaaaa
     9541 tcaatttctt tgattaatac tattatataa ctttaatata gaaaagtcaa ttatttcgat
     9601 tgttattatt atataatttt aaaaaatcaa attctttaat tgttgctatt atataatttt
     9661 taaaattaaa aatataatct ttagacttga atttgattct gtattcacgc cctcaataga
     9721 cggtaaaata agaaaattgt ttatatattg tctccgtagt gttattatac gaaataaaag
     9781 attttaggaa aagtcgttat atcatgctat acctattctt tgtggtataa ttgcaagagg
     9841 tttaatccga taatttataa agagagaaag atattcatga gagatttatt atctaaaaaa
     9901 agtcataggc aattagaatt attagaatta ttatttgaac ataaacgttg gtttcatcgt
     9961 tctgaactag cagagttatt aaattgtaca gaacgtgcag tcaaagatga tctatcccat
    10021 gttaaatctg cttttcctga cttgattttt cattcttcta ctaatggtat acgcattatt
    10081 aataccgatg atagtgatat tgaaatggtt taccatcatt tctttaaaca ttcaactcat
    10141 ttttcgattt tagaattcat cttctttaat gaaggttgtc aagctgagag tatttgtaaa
    10201 gaattttata tcagttcatc ttcgctctat cgtattatta gccaaatcaa taaagtgatt
    10261 aaaaggcaat ttcaatttga agtcagtctg acccctgttc aaatcattgg aaatgagaga
    10321 gacattcgtt acttttttgc acaatatttt tcagaaaaat attatttcct agaatggcca
    10381 tttgaaaatt tttcatcaga gccactatct caattgttag aattggttta taaggaaaca
    10441 agctttccaa tgaatttgtc aacgcataga atgctaaagt tgctcctagt tacgaaccta
    10501 tatagaataa agtttggtca ttttatggaa gtagataaag attcttttaa cgaccaaagt
    10561 ttggattttt taatgcaggc agaaggaata gaaggtgttg ctcagagttt tgaatcagaa
    10621 tacaatatct ctttagatga agaagttgtt tgccaattat ttgtgtctta ctttcaaaaa
    10681 atgtttttca tagatgaaag tctctttatg aaatgcgtaa aaaaggatag ttatgttgaa
    10741 aaatcttacc atctattgag tgattttatt gatcagattt cagtcaagta tcagattgaa
    10801 atggagaata aggataatct gatttggcat ctgcataata ccgcacatct gtatcgtcaa
    10861 gagttgttta ctgagtttat tttatttgat caaaaaggga atacaatcag gaactttcaa
    10921 aatatttttc caaaatttgt ttcagatata aaaaaagagc tttctcacta tttagagact
    10981 cttgaggttt gttctagttc aatgatggta aatcatctat cttatacctt catcactcat
    11041 accaaacatt tggtgattaa tttgctacaa aatcagccta aactaaaggt tttagttatg
    11101 agtaattttg atcagtatca tgcaaaattc gttgcagaga cactttctta ttactgtagc
    11161 aataattttg aactggaagt ttggactgaa ttagaattat caaaggaatc tttagaagat
    11221 tcaccttatg atatcattat ttctaatttt attattcctc ctattgaaaa taagagactc
    11281 atctattcaa ataatataaa cacggtctca ctcatatact tgttaaatgc catgatgttt
    11341 attcgattag atgagtaacc aaaaataaca aaaaaacgct atttcgcgtt tgaactgtac
    11401 ctcaaaagtt agacagaaaa aatctaattt ttggggtgtt tttgttaaga aaagaccttc
    11461 aatcatttaa gcaaaatgta catctagatt tatagccctc taaaactctt gctttttttg
    11521 tagaagatac gaaaaaagcc ataaaaccaa ggcttttcct gttttatgta gatgtttaca
    11581 catgaaaatt gaagtatttt caaaagctaa ttggagtgat tttattcatg atgggataaa
    11641 tgatctggcc aaaaatgatt gagaaatagt tgcttaaaaa gcatttgcat gatactatat
    11701 attgaaagga ggtgataata tggtagaaca aagaaaatca attaccatga aagatgttgc
    11761 tttagaagca ggagttagtg ttggaactgt ttcacgtgta attaataaag aaaaaggcat
    11821 taaagaagta actttaagga aagttcaaag ggctataaaa acattggact atatccctga
    11881 taattatgct cgaggtatga aaaagaatag aacagaaact atcgctttga ttattccgag
    11941 catatggcat ccattttttt cggagtttgc ctatcatgtt gagaaagagt tattaaaata
    12001 taattataaa ttatttattt gtaacgctga tagcgattca caaaatgaaa tcgaatatat
    12061 cgaaatgttg aaacaaaata aagtggatgg aattattggt attacatatt ctgatattga
    12121 caaatatatt ttatctgatt taccgtttgt aagtatagat agacattttt cggaaaatgt
    12181 atgctatgtt acttcagcaa attacaaagg aggacaaact gcagcagagg aactggttag
    12241 aagggataat aagcaccttg cttttattgg ttcaattaat atgtatgaga atgagactat
    12301 actcagaagt aaaggattca gagaaaaagc taaggaatta ggagtagatg tctataattt
    12361 tgaaatgaaa gaacctttaa taaatcctga agatcagata agaatttttt tgcaatctca
    12421 taaagaaatt gatggtatat ttacaataaa tgatatgatg gctctgagag ttattagtgt
    12481 tatgaaagaa ctggggaaaa tagcacctga tgattaccag ataattgggt ttgatggttt
    12541 aaaaacttct gtcgatcaat cttatctagt gtctacaata gttcaagata ttggtatgat
    12601 ggcaaaagaa tctgttgcaa tgatactgaa aatgattaag cgagaagaga ttctagaaaa
    12661 acgaatcgta attcccacat atttttgggg agataaaaca acaaaaaaaa tttaaaaagc
    12721 gcttgacaat taatgaaagc gctgttataa tataatcaac aaatgaaacg tttcaaaaat
    12781 aggctagaag cttgtttaaa aaataaataa aaaatgaaac gtttcaaaaa ggaggaaaat
    12841 gatgcgtaaa ggtacaatgt tatctgttgt tgcggggcta tcgttagcta tacttgcagg
    12901 ttgtagtgga ggaactaact caaaacaagc gagttcttca aatgatatta aagtctgggt
    12961 acaattctct gacgaaacaa atgaaggaaa agcttggcaa aaagttgttg ataactttaa
    13021 tcaatcagga aaaagtaagt acaaggttgt aactgagtat attcctcgta gtggtagtgg
    13081 tggaggatat gaagacaagg ttaatgctgc tattacgact aatagtcttc cagatgttat
    13141 tacccttgat ggaccaaata cggcagctta tgcaaaatct aaagtaatta ctccgctaga
    13201 tgattatcta aaagataata atatggatga tgttttggac agtattaaac aacagggaac
    13261 ttataatggg aaattctatg catttggatt ttctgaatcg aatgttggtg tttattacaa
    13321 taaaaaaatg ttcaaagagg ccggaattgc ggaatcagag cttccaacgc tagaaaagcc
    13381 atggacatgg gacgaattta atacgattgc taaaaaattg aaagatcatt ataacaaacc
    13441 agcaattgat tttcgtatta attcaaacga tgaaatgttg ccatatgctt atatgccgtt
    13501 gatttggtca aataatggtt ctgtcgtaaa cgaagatgga acaaaggcag aaggatactt
    13561 caactccaaa gagagtgtag aagcagttca attcattcaa aatcttgtaa aagaaggcta
    13621 tacaactgtt agtccagtcg aaaaaggttt tgaaacagga gagtatccaa tgcttttgag
    13681 tggttcttgg acgattgctg acatgaatac aaactacaaa gatattgatt ttggtatcct
    13741 tccttaccca gtatctagta agacgaaaaa attagtatcc ccttcaggta gttggcaatt
    13801 agctgtgacg acaaaatctg ataaaaaaga ggccgcatct gaatttgtta aatttgctac
    13861 aaatacagaa tcaagtgaaa ttattagctt ggggaattcg gtccttccaa ttcgtaaatc
    13921 tacaattgaa aatatcaaag ataaagtatc cgaaccaatg cgtttcttga tggaacaaaa
    13981 ttcaaaaaca gctcatgctc gcccagttgt tgtagcatat cctcaggttt ctcgagcttt
    14041 tcaacaagca atgcaagata ttagctatta tgaagaaaat ccaaatgtgc aaaaagtctt
    14101 ggatactcgt acaaaagaaa tgcaaactgc tattgatcag tcactcaaat aatctgtaaa
    14161 aaagaaggtg gaaggaaaat gtttggaact accttcccct ttcttgttaa tagcctagtt
    14221 tgatatatat gattaaagga gatggatatg agtaaagaaa ctgttgtgga tacaaaaaga
    14281 cgtgaaaaaa taaaggataa catattaggt tatagttttt tagctccagc tttaatttta
    14341 ttaggtatct ttttagtaat tccagttgga atggtcattt attacgcttt tacagattat
    14401 tatttgttga caccagatga aagaaaattt gttggacttg aaaattttat tcgattaaca
    14461 aaagatccga ttttcttaaa gagcttcttg aatactttga aatttgttgt ttggattatt
    14521 ccagttcaat tgggagcggc cttaggaatg gctttgattg tcaataaaaa gcgaaaagga
    14581 aatatgtttt ttaaagtggc tttttttgct ccagttgtca tgtccttggt agttatttct
    14641 attctttggc tttatctttt aaatccaaat agtggcttat tgaatgctat tttaaataag
    14701 gtaggtattg cttctcaacc tttcttgact agtcctaaac aagctatgta tgcaattgtt
    14761 tttgtttctg cttggcaggg tgcaggttat cagatgcttt tatttttagg aggaatgcag
    14821 aatattccac aagatgtcta tgaagctgct gaattagatg gattctcaaa atgggctcag
    14881 tttcgttata tcacgatgcc cctactaaaa ccaacagccc tgtttgtatt gttaacaact
    14941 ttaatttctg cttttaagct gattgtacaa ccaatggtta tgacgcaagg tgggccatta
    15001 aactcaacaa ttactatggt gtactatatt tatcaacaag gttttactga tcgtcttgta
    15061 ggatattcta gctcaatcgc tttagtattt acaacgttaa ttggtatgat taacttagta
    15121 caacgtcgcg ttctgaagga ggatgactaa gatgaaacga tttaaaccaa caacaatctt
    15181 agaatatatt ctgttaactt tattggcagg actcttcctt tttcctatgg tttggatggt
    15241 agtttcagct atgaagccag aagcggatgt ttataaaaat ttgactagtt ggcaagcctt
    15301 cttaccaagt ttaaatcccg ctgattggtt taaaccttat caggaagtat ttgagcgctt
    15361 tagtattttt acatatctag ggaacagcat tttttatgct ggaacgtttg ctattggttc
    15421 tattattgtc aatgcactgg ccggtttcgc ttttgcaaaa gtcaattttt caggtaagaa
    15481 aattttattt ggtttcttac ttgctttact tattattcca gtggaaactg tgttaattcc
    15541 acaatttacc attatcaatt ccttaggttt ggtcaataat cgtcttgcag ttattattcc
    15601 aggattggcg agtgtattta atatttactt atttaggaat ttctttattg caattccaga
    15661 agagattctt gagtctgcaa agatggacgg agcaagtatc gttagaattt tctttagaat
    15721 tatgcttcca atgtctaaac ctgcagttgc tacagttggt gttttatcat ttatttcaag
    15781 ctggaatgat tatatctggc cattgatggt tttgacagat tcttctaaat tttcaatgca
    15841 ggttgcaatt acaactatta atacaactca accagtttat atcaatcagg taatggctgt
    15901 attaactatt tcaacgattc cgttgatttt ggtctatgta gtcgctcaga aatatattgt
    15961 tcaaggtctg ggtggttccg gaactggaat aaaataggat atacttatga taaataaaac
    16021 atttacagta gaaaaagcca atcgttttat agcagaaaat aaacatctcg ttaatactca
    16081 atataagcct gaagaacatt tttcagctga gattggttgg atcaatgatc caaatggatt
    16141 tgtctatttt cgtggagaat accatctctt ttatcaattc tatccatatg atagtgtttg
    16201 ggggcctatg cactggggac atgctaaaag taaggacttg gtgacttggg agcacttgcc
    16261 agtggcactt gctcctgatc aagattatga ccgaaatggt tgtttctcag gctctgccat
    16321 tgtcaaggat gatcgcctct ggctcatgta cactgggcat atcgaagaaa aaaccggtgt
    16381 ccgccaagtg caaaatatgg cattttcaga tgacgggatt cactttgaaa agatttccca
    16441 aaatccagtt gcaactggat cagacttgcc agatgagttg attgctgctg atttccgtga
    16501 tccaaaactc tttgaaaaag atggacgcta ttactccgta gtagctgcca aacacaagaa
    16561 taatgtgggc tgtatcgttc tactagggtc cgataaccta gtagaatggc agttcgaatc
    16621 catcttttta aaaggggtag aacaccaagg ctttatgtgg gaatgcccag attacttcga
    16681 gttagatggg aaagattgcc ttattatgtc acccatgcgt tatcagcgtg agggagactc
    16741 atatcataac atcaactcat cgcttttgtt cacgggtaag gtagattggg gagaaaaatg
    16801 ttttatccca gaatcagttc aagaaattga tcatggccaa gacttctatg cgcctcaaac
    16861 attgttggac gatcaaaatc gtcgtatcct gattgcttgg atgcagacat gggggcgtac
    16921 ccttccaacc catgaccaag aacacaagtg ggcatgtgcc atgactttac ctagaattct
    16981 aagattggaa gatggcaaac taagacaatt ccctgttaaa aaaggccaat atcaaatcca
    17041 aatagataaa gattgtcatt accacttagg aaatgataca gattatcttg aatttggtta
    17101 tgacagtaat gtgcagcaag tttacattga tcgtagccat cttattcaaa aaattctagg
    17161 tgaagaagaa caggacacta gtcgacggta tgtagatatt gaagctaaag aattggaagt
    17221 tgttctagat aaaaattcca tcgagatttt tgtcaatcaa ggtgaagcaa gcttgactgc
    17281 aacttattac ttaacggtgc cagctgagct atcacgaatt gattaaaaat taagttattt
    17341 ctcctaaaga aaaagttctc tttctaaaat agtggaaaga ggactttttg tgttttgggt
    17401 atataagctt agtttatggt atttgtaaaa ttggtgttgg attatgattt aaactagttt
    17461 tctaaagaat ttgaaaaaaa ttttatttaa gcaaaaaaag ccctatatta taagactttt
    17521 cctgttgtat ttatatgccc cctacaggga tcgaacctgt gacccacgga ttaagagtcc
    17581 gctgctctgc cagctgagct aaggaggcaa agaaaaaagc tgtattggtg ccgaaacttc
    17641 acggtttgta ttgaacccgc gcaattaagc aggtgggcaa ctcgctctaa ctgaagctgt
    17701 ttccgtgtga gacggcctac atgctgttag aagacttttg tttccctaat aatacaaaaa
    17761 atagtcggtc aacacttaag tgtgaagtcg tacaccacag cgtttctata tttatatgat
    17821 accacttttt taaaaaaaat caagaggaaa gtgcaatttt ttgaaaagga tttcagattt
    17881 ttcgcaaatg gtcgatagct tcctttcttt gagccaaagc ccgttcatat ttaccagtat
    17941 cttctgcttg gaaatagtga tgattacgaa ttttttctgg cagatagtct tgctttaccc
    18001 aatttccagg atagttgtgt ggatagagat agtcttgggc attccccagt tccttgcttc
    18061 cactgtagtg cccatcacgt aggtgtcgcg gaataggcaa gtgccctgat gttttgaggt
    18121 cagcaagtgc cttatccata gctacatagg ctgagttgga ttttggagaa agggccaaat
    18181 caatcacgac attggcaatg agaatgcggg cttcggggaa accaatcctt tgtgcagcat
    18241 ccagagcagt cacggtatga atctgggcct caggattggc taagccgata tcttcatagg
    18301 cgataacagt caagcgacga gcgagactag gcagatcccc agcctcaatc aagcgggcag
    18361 tatagtggag actggcatcc acatctgagc cacgaataga cttttgcagg gcagatagaa
    18421 catcatagtg accgtctcca tccttgtcca tagtgatgta gcttctctga agactatttt
    18481 ccatgatgtc taaggtgatg tggcgaatgc cctcgtcatt ctcaggggta gatagaacag
    18541 ccaagtccag tgagttaaag gcagagcgaa ggtctccgtt tgtagaggtt gcgatgaaat
    18601 ccagcgcatc ctcatctagt tctattggaa aatcaaaacc acgttcaggg ttacttagag
    18661 ctatctgcag ggcctctttg acgtcttggt tagacagagg ttccaactcg aaaatttgaa
    18721 cacggctacg aatggcagga gtgacagaga agaaaggatt ttcagtcgtt gctccaatca
    18781 tgatgaccag tccactttcc aagagaggca agaggaagtc ttgcttggtc ttatctagtc
    18841 gatgaatttc gtctagcaat aggacgagac caccagaaaa tttagcttct tccgagattt
    18901 cttgcagtcg ctttttacta tcaactgtcg cattgaaagt tcgaaaggca tacttggtcg
    18961 ttccagcgat ggcagaggca atactggttt tgccgattcc cggagggcca tatagaatca
    19021 tggaggacag gcggttggct tccaccatgc ggcggatgat ttttccaggt ccgaccagat
    19081 gctcctgacc gatgacctgg tcgatggttt tagggcgcat gcgaagcgcg agattgtctg
    19141 gcatagcagt cctttctaac gtggatttga gtagaatgac tcatctacta tatcttacta
    19201 tgtccattct agcctattag ttgtgatatt tcaatggttt tgtaataatc agggagtgag
    19261 atagaatctt ttttactatt taatttaatg aggagaggta tcagcatgag agatttgatt
    19321 ttccttaaag ctcaaaatag gatagttgag cctaaagaag tggaagtgct gacttgagaa
    19381 ataatattgc tgaatgtcat tgtatgaact ataatgaaaa gagaggtgat aagcaatgga
    19441 aatgatggac caagtcagga aattttgatt tttacaaaac aaattcgtca ttggattctt
    19501 agtgatcaag ttatttcagg gaaaagaaaa cttttcttcc gggaagatac tccaaaagag
    19561 attttagatt tgtacgaaaa cattaaatct aaacttgatt ttgcttacca agaagttcat
    19621 tctaataatg ggttgaaaaa atatgaaaaa tagaataatt gatgtttttg aagtagtaaa
    19681 tcgcctcctt gtaataactg ttgaaaatcc tgatttcgaa gacttgagag ttaatcatac
    19741 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggtaa
    19801 ggcgacgttg acgtggtttg aatttgattt tcgaagagta tcagtttgta aaaattggag
    19861 ataaaaaata tagagtacgc agtgttccta tgattcattc aactccgcct caatctgtct
    19921 tagatcgaga tacttttaca attgactata cagatgatga attgctcgat aaagaagcag
    19981 tttttactac tcattagaaa aataggtatg aataaattgg cttcccttag aaccacatct
    20041 aggggctttt atgtataata gaataataag tatcactcct ttacaatacg tgtaacacgt
    20101 gttataatgg tgttgtcagg aggtaaaagc gctatgccta tgacacaaaa agagatggtt
    20161 aaactcctta cggcccatgg ttgataaaga ctagaggcgg taaaggttcc catattaaaa
    20221 tcgagaagca aggggaaaga cctatcacaa tccctcatgg tgagctgaat aagtacactg
    20281 aaagagggat aagaaagcaa gctgggttgt aaaattcagt ccctgctttt tgatatggag
    20341 gtagtgaaat gttagttacg tatccagctt tattttatta tgacgacaca gacggaacag
    20401 aagcgactta ttttgtccat ttcccagatt ttgaatactc agctacacaa ggagagggga
    20461 tttctgaggc tttggctatg gggtcggagt ggctagggat aactgttgca gatttgatag
    20521 agagtgatgg agagttacct cagccatcag atatcaatag cttgtcttta attgataatg
    20581 atccttttaa agatgatgaa gatttcgtgt caacctatga ccttgataaa tcttttattt
    20641 ctatggtatc tgttgatgta tcagaatacc taggaagtca ggaacccatt aaaaagactt
    20701 tgaccatacc aaaatgggca gataagttgg gacgagaaat gggacttaac ttttctcaga
    20761 ctttgacaga cgctattgca gataagaaag ttcaagccta agattaagcg tggtatcgtg
    20821 gtaatagtca ataaaaaagc acgtccactt gtgctagtta ctcgcctatt gattttatag
    20881 atttattagc cctttcgagg gctttttata ttgattttta tgagaaatga agaaatcaga
    20941 cttttaagaa aatcactgat accaagggtt taaatgaggt aatatggtat aattaggaca
    21001 taaaataatt ttgtggtaag atggtagtat ctattttagc atatttccga gcaatcgggg
    21061 cgattaaaga gtcgcataga aagaggacaa aatggcaaca tacggatttt tagatgtttt
    21121 agaggaagag ttggacaaga actttccctt tgactttgag attagctggg acaaacgcaa
    21181 ccatgcggta gaagtgagtt ttctattgga agcgcaaaat gctgcaggtg tggagatggt
    21241 ggatgaagac ggagaggttt catcagatga cattcttttt gaggaagcgg tccttttcta
    21301 caatcctgcc aagtcaaccg tcaatgcaga agactattta acggttatcc cttatctacc
    21361 taaaaaagga ttttctcgcg agtttttagc ttattttgcc cttttcctca aagatactgc
    21421 ggaggttggg ctagataccc tcatggactt tttggaagat ccagaagcag aggaatttgt
    21481 tatggaatgg aatcaagaag tctttgaaga aggaaaagtt ggcttggaag agggagaatt
    21541 ttatccttat ccaagatact aggagttggt tggaggtgtt atgaagaaaa ttgggactta
    21601 tttggtttat gtgctagctg ttgtctttat tatgctagct tttgcttgtg gaacaatcgc
    21661 atttgcagag ttggggtatt ccgcagtttt agcctttact tttggttatg ccttcgctct
    21721 tctaagcatg tatttaatct ttattcttca tgagctgggt catgcttttt gtggctactt
    21781 gacaggctat cggctggtgg cttttggatt aggacatttt attttgacca aaaagtcagg
    21841 caggtttcat cttagtagaa cagccattct gaaaaatgtt ggtgctcaat acattggttt
    21901 aaaagaggat gaaagcgatc aaagaatcat cctgatgctt tcaggaggct tgatggttca
    21961 tctcggcttg atattattgg cgatagtgtt tggctttttg acaagaagct ggtattttgc
    22021 agggacttgg atttttctta atttatcttt cttcctaaat aacattttgc cagtcgacat
    22081 caccgatgga gcaaaaattt gggaattact acaacaccct gaaaatacca aatacgccta
    22141 cctggtattg agacattctg ctcaaacttt gctggctcct caagaatatg atttgaaaga
    22201 ctttgttcaa gcagttcctg aggatgcacg agggagtttt gcggatggtg tattaggtat
    22261 gcaaggtgaa gtttccattt tggaagggaa ggaagaagta gctaaacagc agtttcaagc
    22321 attacttgag aggacaacta ctccgatgat gcagacagtt gcccaactat ccctgcttca
    22381 tatcgccttg ttggaaggag attttgagca agcggagcaa tatgctagta ttcgacaggt
    22441 caaatcgttt ctgtctctca aactgtccaa tcttcaagtg atacaagcct ggtatcaatt
    22501 aaaggtgaag aaagatgtag atcgaactcg taaggctctc aagattgcta gacagaaaat
    22561 ggatagtagt cgaatgttga gggacgagaa acgctattat gaaaacttgt tagcagagct
    22621 ggaaaaggaa atgttagaag gaactgaaga tggaactaga aatttctgat ttccaaggtt
    22681 gcaagattgc cctcttttgt ggggataagc tactgacgat tttgcgtgat gacaaggacg
    22741 atatcccttg tcccaacatg tgggagttgc caggtggtgg ccgtgaaggg gacgaaagcc
    22801 cttttgaatg cgctcggcgt gaagtttatg aggaactggg aattcattta gatgaagact
    22861 gtctgctttg gagcaagatt tatcctagcg taatttttaa aggcaagaaa tcggtcttta
    22921 tggttggtca gctaagacaa gaacaatttg acaatatcat cttcggagat gaaggacagg
    22981 gctatcagct gatgaatgtt gaggaatttc ttagttccag tcaagttgtg cctcagttgc
    23041 aagagagatt aaaagattat ttaaaagtaa gtgattagaa aggatggttc agttaaattt
    23101 ctaaactgaa cccgccctaa acactgtgcc aaaaagataa acttctctta gacacaagcg
    23161 tcttcagaga atttcctatt ttggttttgt gttttacggg cttggtatct taatgatgga
    23221 aacatggcaa gagttaaaag ttacagtgaa gcgtgaggga gaggagttgg tttccaatct
    23281 cttgattgag ctgggagcgc aaggtgttgc gattgaagac agtatggact atgtgggaaa
    23341 tgttgaccgc ttcggcgaga ttttcccaga ggtcgagcag caagaagaaa tcgtagtgac
    23401 agcctactac cctgacacgg tggatgtgac agtggttgag gcggacttgc aggctcgcat
    23461 atcagaattg acggatttta tggatttggg agagttaaaa ataggtacga ctgccttggc
    23521 tgaggaagac tgggcagata actggaagaa atactatgag ccagctcgta tcactcatga
    23581 tttgaccatc gttccctctt ggacagacta tgaggcgact gcgggagaaa aaattatcaa
    23641 gctggatcct ggcatggctt ttggtacggg aacccaccca actaccaaga tgagcatttt
    23701 tgccttggaa caggttcttc gtggtggcga aacggtgcta gatgtgggaa ctggttcagg
    23761 ggttctctct attgccagct cgcttctggg ggctaaagaa attttcgcct atgacctgga
    23821 tgatgtggca gttcgtgtgg ctcaggaaaa tattgagctc aaccctggaa tggaaaatat
    23881 ccatgtagcg gcaggcgatt tgcttaaagg cgtggagatt gaagcagatg tcatcgtggc
    23941 aaacatcttg gcggatatcc tcattcatct gacagaggat gcttatcgct tggttaagga
    24001 tgaaggttac ctgatcatga gtggcattat caaggataag tgggacatgg tgcgcgagtt
    24061 ggctgaatca gctggatttt tcctcgaaac tcacatggtt caaggggaat ggaatgcctg
    24121 tgtctttaag aaaaccaagg atatctctgg tgtgattgga ggctagcatg cagcagtatt
    24181 ttgtaaaagg cagtgctatc tctcctgtca ctatcgagaa caaggaaacc agtaagcata
    24241 tgtttcaggt tatgcgcttg aaagaagagg atgaggttac cttagtcttt gatgatggca
    24301 tcaagcgctt ggcgcgcgtg ctggatatgg aaaatcgtca gtttgagttg gtccaagaat
    24361 taaatgacaa tgtggaacta ccagttcaag tgaccatcgc atctggattt cccaagggag
    24421 acaagctgga gttcatcgct caaaaagtaa ccgaactggg tgctagccaa atctgggcct
    24481 ttcctgcaga ctggtcagtt gccaagtggg atggcaagaa attgggtaaa aaagttgaaa
    24541 aactagaaaa aattgccctt ggagcagccg agcaaagcaa gcgtaatatt gtaccaagta
    24601 ttaaactttt cgagaaaaaa gcagattttc taactcagct ggaccagttt gactctatca
    24661 tagtagccta tgaagaatca ggtaaagaag gagaagccgc tgcgcttctg caagcagtca
    24721 ctggtcttga aacaggagcc aaactgctct ttatctttgg tccagaaggc ggtctctcac
    24781 ctgcagaaat cgaaagtttt gaagctaagg gagccgtttt ggtaggccta ggtcctcgta
    24841 ttttgcgagc agaaacagca ccgctttacg ccttatcagc ccttagtgtt ttagtagaat
    24901 tagagaaata agaggaagaa aatggaacaa aaacaccgtt cagaatttcc agagaaggaa
    24961 ctctgggact taacagccct ataccaagac cgtgaggatt tcttgcgtgc aatcgagaaa
    25021 gctcgcgaag acatcaacca gtttagccgt gattacaagg gcaatcttca cacttttgag
    25081 gatttcgaga aggcctttgc ggaattggaa cagatctaca ttcagatgag ccatattggc
    25141 aactatgctt ttatgcctca gacgacggac tatagcaatg acgaatttgc caatattgcc
    25201 caagctggga tggaatttga aacagctgcc agcgtagcct tgaccttctt tgacgatgcc
    25261 ttggtggcag cagacgagga agtcttggac cgtttgggta aattgccaca tttaacagct
    25321 gccattcgtc aggctaaaat caaaaaagcc cactacttag gggcagatgt ggagaaggcc
    25381 ttgacaaatc tcggtgaagt tttctatagt ccgcaggaca tttatactaa gatgcgagct
    25441 ggggattttg aaatggctga ctttgaagcc catggcaaga cctataaaaa cagctttgtc
    25501 acctatgaga atttctacca aaatcacgag gatgctgagg ttcgtgagaa atccttccgt
    25561 tccttctcag agggacttcg taagcaccaa aatacggctg cagcagccta tctggctcag
    25621 gtcaagtctg aaaaactctt ggctgatatg aagggatatg actctgtctt tgactatctt
    25681 ctagctgaac aagaagtgga ccgtgtcatg tttgatcgcc agattgacct catcatgaag
    25741 gactttgcac cagtcgctca gagatacctc aagcatgttg ccaaggtaaa tggtcttgaa
    25801 aagatgacct ttgcagactg gaaattggac ttggacagcg ccctcaatcc tgaagtgact
    25861 attgacgatg cctatgattt ggtcatgaag tcggtagaac ctttggggca agaatattgt
    25921 caggaagttg ctcgttacca agaagagcgc tgggtggact ttgctgctaa cagtggcaag
    25981 gattccggtg gttatgcagc ggacccatat cgcgtacacc cttatgtact catgagctgg
    26041 acaggccgtt tgagcgatgt ctataccttg attcatgaaa tcgggcattc tggtcaattc
    26101 atcttttcag acaatcacca aagctatttc aacgcccaca tgtcgaccta ttatgttgaa
    26161 gcaccgtcga ccttcaatga attgctactc agtgattact tagagaacca gtctaatgac
    26221 ccacgtcaaa aacgcttcgc tctggctcat cgcttgacag acacctactt ccataatttc
    26281 atcacccacc tcttggaagc cgccttccag cgtaaggtgt atacattgat tgaagaagga
    26341 gaaaccttcg gagcaagcaa actcaacagc attatgaagg aagttttgac agatttttgg
    26401 ggcgatgcca ttgaaatcga cgacgatgca gctttgactt ggatgcgcca agctcactac
    26461 tatatgggct tgtatagtta cacttactct gctggtcttg tcatctcgac agctggttac
    26521 cttcatctta aaaactcaga aactggagct gaagactggc tcaatctcct caaatcaggt
    26581 ggtagcaaga caccacttga gtcagccatg attatcggtg ctgatatttc aacagacaaa
    26641 ccactccgtg ataccatcca attcttgtct gacacagttg accagattat cgcctacagt
    26701 gctgagttgg gggagtaagg ggatagagag gttgttatag aatgggtatg gacagttatt
    26761 tgcttaaaag tccatgttta aatcccccat tccttttcga ggaattcttt gcccttctct
    26821 gtaatggtaa gtgaacgtgg cgtttgtgca gggatgacca attgtttttc actgaaaaat
    26881 tctaaaagag cattgccgag agctccgccg acatgatttt tacgttcgct ccaatccaaa
    26941 catttagggc aaaatttccg ttttttcttt ttcaattcat ccgtatcaat gtgtaatttt
    27001 ctttggaaat aagacttccc agcttcagtg agttggaagt ctttttctga ttcgctgagg
    27061 agattttctt gcaagagata attggtaatg gaaatgccaa gctcaccagc aatatggtca
    27121 tagcaggtgc gagcgacctt taattccttt ttgtgaatgt gttgtttata acttttgaca
    27181 tcacgctgag gagagtagaa gctgagaaat tccagcattt ctgcaatggc agcacttttt
    27241 aaagaataat aatgaaaacg tccataggtt tgtagagtgg ttacctgcgc ttcggtaagt
    27301 aatttgaggt gatagctgac agtatgttgc ttgattttgg taaagctggc aatttcgtta
    27361 accgtgtgag cttttccatc cattagaata tctaaaatgt gcatccgaga agggtctgat
    27421 aagagttttg tgatgatgaa aatatctggt ttcataaaaa ttttctccaa atttcatata
    27481 tcgatgattt tctatctttt attatactat aattaaagca caagaaaaat agattttaaa
    27541 aatgttttac tagagaatat tttaaatttt attgtctgag tttaaatgga ggtaaaatta
    27601 caaaagtaat tgcagcagta tccacagttg aaggacgtta atcttaagat tacattctca
    27661 acattttttc aaaagtgaga tgaattaaca aagtatccaa catgctctat ttgtggggga
    27721 aagaaagagt gaagaagtta agtgttaaaa atctaaaaaa gcaatatggt tcttatgaag
    27781 ctgtcaaggg aattagcttt gaattgggag acggagagtg tttgggtatc ttgggaatca
    27841 acggtgctgg caaaacatcc actttaaaga tgatttactc actgacctca atttcctcag
    27901 gagagattga tatcttgggg caaaatattg aaaccaatcg tcgtaagagt aaatcttgtc
    27961 tgggtattgt agggcaggag gatatgctgg acatgacctt gaatgtttat gataatcttt
    28021 ttgctcacgg tctatgttat ggtatctcat ctgtcgaact taggaagaga atcgattctc
    28081 tcttggattt tgttcaactg agcaaacatg cgcaaaagat ggtgaatcag ctgtcgggtg
    28141 ggatgcgacg acgtcttgtc ttggcaagag ctctcatcaa tcggcctgat attatcattt
    28201 tagatgaacc gacagttggt ttagacattc aatcccgcaa tattatttgg gataaacttt
    28261 tggaattgaa ggaattaggt gtttctatca ttattacttc ccactatatg aatgagattg
    28321 aatatttgac agatagggtg ctgatgctcc accaagggac tatcaaagaa gaaggaactg
    28381 tagaagactt gctcatcaag tatgatgctg acaaccttga gacgcttttt tgggggttga
    28441 ctgggacaga gaaggaggac ttgcatgttt aagttatcat ttcactccat cggacacgtt
    28501 gtggtacgca actacatgag ttttagaaat ttatttaaaa tttcaattgt ccccaacctt
    28561 atcgaccccc tcttttatct tttagcaatg ggatttggag ttggtgctta tttgacgcat
    28621 gttaacggta tgctctaccg tgattttgtc attacaggtt taattgctgc gactgccatg
    28681 tctgcggcca ccgcagaaac aacggtcaat gcctttatcc agtataagat tgaaaagact
    28741 tatgatgcta tgttgatgac gccaatcaat acgaatgata ttgtggtagg tcaggctatc
    28801 tgggcaggta ttcgtgcagt gattttcggt gggatttttt ggctgatttc catgcttatc
    28861 acagcgcatt ttcatgtctt gatgttattg attcctctga ttttatttat agtgggttat
    28921 ttgtttggtg ttttgggact aatctttacc tacttggcgc cgtctaggga atttctgaat
    28981 tactacaatg ttttggtaat ccgtcctctt tatatgtttt cagatacctt ctttcccatt
    29041 acttccttgc ccccaatact tggtgatttg acttggtttt ctcccttgta tcacgctacc
    29101 cgcatgattc gtattatatg gggaggtgag gtgacaggtt tgtatcttca tcttatctgg
    29161 ttgatagcct tggcgctctt gataacggtg cttcctatgt atatgttaca tcgtagatat
    29221 tatagatagt ctaattattt gtgatgttgt agtcatattc taatttatac taaacgttat
    29281 tcgaatttgg acaggtatgg gaactgtgcc tatcaatatt gtaatttatg gaagttgaaa
    29341 tagtacggtt cagtttttaa atattgttag aaattgtttt aaattcccta atcaatttgt
    29401 atagttttta tttcacttta ttataactag tttttcgcaa tttttgagac aggaatgtga
    29461 tttttgtgat aaggttctat cattacaagt ttatttgttg taatatggaa taaatcattt
    29521 atatatcttt tcagaaatat gctgtttctc tgaatataaa tgtctttttc tttttaactt
    29581 aattttacaa attggtaagg tcatttaaga ctgccttttt gaacagttgc tagaaatgta
    29641 gaggtattga ccatgtatca agatttacta agaaaaatag cagaagaaaa accaaattat
    29701 aaccaggagg aaatccagtg gttgcttgat catttgggag atccttctcc agaaattcgt
    29761 gatgatcttg tttttacaag ctttgctaga gggattcagg aagagctatt tacacaggag
    29821 caatttcatt tcattgctga ggtggtctta gctgatggag ggttagataa agagattgat
    29881 aaggtaggct tgtcaacact tgaacgttct tttagggcac ttgtttatgc aaatctcttg
    29941 tctgtagatg ctaaccagca atcggttttt tatcagggat tacaatcaga aattcgtaat
    30001 gtccttttaa atcaaggctt gcactatctt tcaaaagaaa aggatacaac aggtttctca
    30061 agtcagtatg gttgggttca cgcttttgca catggagccg atttactgaa agaggtggtt
    30121 tgtcatccag actttcctaa aaacagagtt catgaagtat ttgatatact tggccaacta
    30181 tttaaaagaa tgtcgattcg ctttacagat gatgaggatt ggcgtttagc aagagtgatc
    30241 tatgaaccta ttttacaagg gaagttagcg caagaacaag tagcttcttg gataaaaact
    30301 gttgattttc cgatagaaga aagggaggat ttttacaaat tttccaactt cagaacctgt
    30361 ctgttggaag tctatgtcca acttgaccag agaaatagtt tacaagatga gttgaaagaa
    30421 gctatccagt cttttcaata ctagagatta gctaatagtt ctatgatttt caaaaaattt
    30481 ccaatcaatt ttcttgaaac cctttcctac ttttgataga ctagtatcta gtttttgaaa
    30541 aaaggagaaa gaaaatgaaa aaatttgttg ctgagttaat cggtacgttc atgcttgtat
    30601 tcgtcgggac aggagctgtt gtttttggaa atggtcttga tggccttggt caccttggaa
    30661 tcgcctttgc ctttggtttg gcaatcgtgg tggcagccta ctcaatcgga actgtttcag
    30721 gtgctcactt gaatccggct gtttcgattg ctatgtttgt aaacaaacgt ttgtcatctt
    30781 cagaacttgt aaactacatc cttggtcagg ttgttggagc tttcatcgct tctggcgcag
    30841 tcttcttcct cttgggtaat tcaggtatgt caactgctag tcttggtgaa aatgccttgg
    30901 caaacggtgt cactgtcttt ggtggtttct tgtttgaagt catcgcaact ttcttgtttg
    30961 tcttagttat catgactgtg acttcagaaa gtaagggcaa tggcgcgatt gctggtttgg
    31021 taatcggttt gtcattgatg gcgatgattc ttgtcggatt gaagattact ggactttcag
    31081 taaacccagc tcgtagcttg gcaccagctg tcttggtagg cggcgcagcc cttcaacaag
    31141 tttggatttt catccttgca ccaatcgctg gtggagttct tgcagccctt gttgcaaaaa
    31201 atttccttgg aacagaagaa taattgaaac tcaaaaagcc ttgctcctca tcttgaggaa
    31261 cagggctttt tcgtatgata ctcttcgaaa atctcttcaa accacgtcag cttcaccttg
    31321 tcctaggtat ggttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttaag
    31381 ctgacttcgt cagttctatc tgcaacctca aacactgctt tgagtaacct gcggctaact
    31441 tcctagtttg ctctttgatt ttcattgagt atgactttag cggttgtcaa ttttctctgg
    31501 ataaaggtcg tgttggaaga ggcgttgttc tgccaagccc tcatacttag ttccttgctt
    31561 accgtagtta tagtaggggt cgattgaaat gccaccgcgc ggagtgaatt ttccccagac
    31621 ttctaaatag cgagggtcta gcaagttgac caagtctttc ccgatggtgt tgatacagtt
    31681 ttcgtggaaa tctccgtgat ttcggtagct aaatagatat agtttgaggg attttgactc
    31741 gacacagagc ttgtcaggaa tgtaggaaat atgaatcgtc gcaaagtctg gctgagcagt
    31801 gatttgtccc agcagagaca tatcgaggat atggtgacga atgccctgtt ccttagcgat
    31861 ttctctagta atttgaattt cgaggtgatg acgttggccg taggcaaagg tgacagcttc
    31921 gactgtttca tagtgttgca tggcccagaa aaggcaggtt gttgaatctt gaccaccact
    31981 aaagacgacc aaggctgatt gacgtttcat agtactcctt ccaaaatggg aaatgttcag
    32041 agcacgcaaa aagctcccat tagggagcta aaaaatacca aatcgagttt ttttagcgat
    32101 ggcatatccc aaacatcgta atattctact tatatagtaa aatgaaataa gaacaggaca
    32161 aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt
    32221 ctagtttcaa tctactatag tctagcatat tttttgaaaa atggcaaaga gcaagaaaaa
    32281 agagaccaaa gaaagtactt ggtctctcgt ttgattagct caattcagca atgatggcct
    32341 tgatttgttc tgctgtgtga acacctgcaa cttgtttgac aacttggccg tcttttttga
    32401 agagaagagt tggaatagac atgattccaa aagcacgagc tgtgtttgga ttttcatcaa
    32461 cgtccatttt aacgattttc aagacatctt ctgaaagttc ttcagacaat ttgtccaaga
    32521 ttggaccttg catacgacat ggaccacacc aagttgccca gaagtctact aagaccaaac
    32581 cgtcttttgt ttcttgttcg aatgttgcat ctgtaattgc ttttgccatt gtatttctcc
    32641 tttttttagt tatattggct taaatcttgt ttcatgagat agaagaagat atctccataa
    32701 gtcccatggt agtccaaatt atgacccttg taagttaatt tttggacagg gtagtagtct
    32761 gcgacgccga taaggcaagc ttgttgcgaa cgttcaaagt cttcataaga ctcgaaagtc
    32821 acagttcttt cgttcttgct ggcatctata taggtaattt caatcatatt taaaactcct
    32881 ttgtttaatg ctaactttat tttactcctt ataaaagaga atgtcaagaa aaatgattgc
    32941 gcacgcaact ttttttaaaa tcatcttaaa tcaagaaatc caaacctgct tccaagcttt
    33001 cttcgacagt cttttgtagc gaggccagtg tcttttgccc atcatttgtc aggcagataa
    33061 aactagagcg tctatcttga tggcaacaca tgcgactgag tagaccgcaa tttttagctt
    33121 ccaagcgagc caccatccta gaaactgcgc tcgggctcag atgaagctta tctggcaggt
    33181 caatctggcg tagagatttt tcttcagcca agtccagata gtagagcagg tagaactctt
    33241 tcaaggtcag actttgctcg ctctgttggg caatggtctc ttccaagaga ctttcaattt
    33301 ctttctgacg ccgattgaag tcaaaccatt tttccaaata ggtcatagtg tctcctttct
    33361 ttttagagtc ataaatagaa gaaagtccat taacgggcag tctctgcgtc acaagatgat
    33421 tgcgcatgca ataattatac tacttttcaa gaatactggc aagctctgtt ttttagtggt
    33481 tttctttttt actgtctata tttttggtaa aaatcaactt ttacttggat gaaggttttg
    33541 gcttcacgta ggagttgaag aagagtggcg cgggtttcaa actcttctct tgtcttgggc
    33601 agactgcggt tccggaagac ttccagataa cgttcaattt catctagcaa atcagaagca
    33661 ggattggtct ggctcagttg acctgcaatt tttgaaaaga gttgcgctaa gatcaggctt
    33721 tcactggcgg caaggtgaca agtgttaatc tgttgggcca tgtttctcag gatacgactt
    33781 tgtcgttgtc tcatctcaaa gtagtggata tggtagtcgg tctggtgaaa gaggtggtca
    33841 gagtgatcca aatagaccag tctgagggct tctttcaaaa gcgtgtctaa ttctgctacc
    33901 agctgtgctc ggttgcgtcc gtctcctctg gataaatagt atttgaagcg ctggaggata
    33961 tcttttaact tttcttccac cagcgtgtgg tagtgctgga tttcctcttc tcgtgaaggc
    34021 atatagagat taacaagcaa ggcaaatcct gtaccaatag caaagagaag gaattcgttg
    34081 actaggaggt ctggagaggt tgactcttga accaagagat ggctaaccaa aaccgtgctt
    34141 ggtgtgatgc caatttccca gcccatcttg taggctaaag gaacgtagaa ggccagatag
    34201 aggccgagac tccagatatg aaatccgctc aagtgaaaag ctagaacgcc gatagccaga
    34261 gctagaagca tagaaaaaag acgattgcga gccagtttta aagtacttct acgcgtatca
    34321 gataggctca agagagcgat aattccagcc gaaactgctg acgaaagatt gagaaaataa
    34381 gcaagcaggc aggcaagaca ggtagctaag atgagcttgg tcgtacgttg gctaatagac
    34441 ataagaattt cctaataagt tagaataaaa gcgtaaaaga caagacatga gcaggcttgc
    34501 cttgatgagt tattttttac gggttgctgc gtattcggca acggcggtaa agaggacatc
    34561 tgtagaagag ttaagggctg tttcacatga gtcttggatg acaccaatca caaaaccaac
    34621 cccaacaatt tgtatggcaa tatcgttaga aataccgaaa aggctacaag caactgggat
    34681 aagaaggagg gaacctccgg caatacctga agcatcacag gctgagatag ctgctaccac
    34741 actgaggaca aaggctgtgg caaagtcaac aggaattcca agagtgttaa ctgtaacaag
    34801 ggtcaaaacg ttaatggtaa tcgctactcc agccatattg atagtagaac cgagtgggat
    34861 agaaacagaa taggtatctg ggttgagtcc aaggtcatgg cagagtttca tgttgacagg
    34921 aatgttagtc gcagaactac gagtgaaaaa ggctgtcaca ccgctgacac ggaggcagtt
    34981 ccaaactaga gggtaaggat tgcgtctcat aaagaagaag gcaatcaaag ggttgaccac
    35041 aggggcaaca aaaagcatag tcgttactaa tagaaccaat aaaataccgt agttggcaag
    35101 gcttccgact cccttgtcag aaatggtttt aaaaacaaga ccaaggattc caaatggagc
    35161 cagattgatg atccattcga caattttaga agtcacgtca gcgatagttt ttagcaattc
    35221 tttactattt ttactggctt ctctcatagc gattccaaaa atgactgccc aagataagat
    35281 tctaatatag ttagcagtaa gcagggcgtt gactgggttg tcaaccagtt tgagcaagag
    35341 gttgctgagg acctgcccaa tcccatctgg tggtgcaatt tcagtattgg cactatttag
    35401 ggtaatttca atagggacga tgaaacttgc tagtacagct acaagagcag cggcgaaagt
    35461 ccctatcata ggatatacaa gaaaacaaca gttttcatat tgctatcttg tcccttttga
    35521 tgttggaaag ggcattggca acgagggcaa agactaggat aggagcaaca gcttttagac
    35581 ctccaacgaa taaatccccg agtagcccaa tccctgagag attaggaagg gtcagtccta
    35641 ggattcccca caaagcatac caatcaagat acgcttgaca aggcttgcct tattccaagc
    35701 atgaatgatt cttttcataa taatctcctt tttgtgtagt gattatgatt atagtataaa
    35761 tgatagacaa aatcaagaat tttctgtcta ttttttgaat atttatggag aatgagactg
    35821 atgaaaatat ggtataatga aataaaggag ttttatatgc aaaaatttat tcaggcttat
    35881 attgaaaagc tagatgtgac aaccattatc gagaatattc taaccaaggt catttctctt
    35941 ttactgcttt tgattgtatt ttatattgct aaaaaaatgc ttcataccat ggtgcagaga
    36001 attgtcaaac cttctctaaa aatgtctcgt catgatgtcg gacgccaaaa aaccatctca
    36061 cgtttactag aaaatgtgtt taattatacg ctatatttct ttttactcta ctgcattttg
    36121 tcgattttag gtttgccagt ttctagtttg ctggctggag ctggtattgc tggggtagcg
    36181 attggtatgg gagcccaagg ctttctgtct gatgtcatca atggcttttt catcctcttt
    36241 gaacgtcaac tggatgtggg agatgaggtc gttctgacaa atggaccgat tactgtatcg
    36301 ggtaaggttg tcagtgtggg aattcgtacg acacagcttc gtagcgagga gcaagccctt
    36361 cactttgtcc ctaaccgaaa tatcacagtt gttagcaatt tctcacgcac agactagacc
    36421 tgttatttta agtaatttgt ggtacaatag agggagttta ataaggagaa aagatggttt
    36481 tagaaaagca gttgggcaat ggttgtacct ggatagacct agacctagga aagttgaata
    36541 aactagaaga cctttctgaa atttacggtt tggacaagga aaccattgaa tacgcactgg
    36601 atagaaacga gcgcgcccac atggattacc accgtgaaag tgggacggtt acctttatct
    36661 ataatgtcct agacgtaaaa aaggacaagg cctactatga gacttttccc atgaccttta
    36721 ttgtcgagca tcgtcgcctg attaccatta gtaataccaa gaacgcctat gtcattgaac
    36781 agatgactcg ttatctggag agccatgaca cgctttcgat ttataagttt ctctttgcca
    36841 gtctggaaat tatcagcaat gcctactatc ctgtcattga gcagatggac aagagtaggg
    36901 atgaggtcaa tgacctcttg cgccagcgaa ctaccaagaa aaacctcttt gccctgtctg
    36961 atttggagac tggtatggtt tatctgacgg cagctgccaa acaaaatcgg attttgttag
    37021 agcatattca aggtcatgcc ttgtatcgta gttttgatga gattgagaga gaacagtttg
    37081 atgatgccat gattgaggct catcagctgg tatccatgac agacctaatc tctcagattt
    37141 tacagcagct ttcagcctct tacaacaata ttctaaacaa taatctgaat gacaatttga
    37201 caaccttgac tatcatttca gtcttgctag ctgttttggc agtcgtgaca ggctttttcg
    37261 gaatgaatgt tcccttacct ttaacagatg agccccatgc ttggctctat atcagtttgg
    37321 ctagtgcagg tttgtggatt gttttatcct tgttactaag gaaaattgcg aaaaaaagtt
    37381 aagaaaagga gccagaatgg cgattgaaaa ttatatacca gattttgctg tggaagcagt
    37441 ctatgatctg acagtcccaa gcctgcaggc gcagggaatc aaggctgttt tggtcgattt
    37501 ggataatacc ctcattgctt ggaacaaccc tgatggaacg ccagagatga agcaatggct
    37561 acatgacctt cgggacgcgg gtattggcat tatcgtagtg tcaaataaca ccaaaaaacg
    37621 cgttcaacga gcagttgaga aatttgggat tgattacgtt tactgggcct tgaagccctt
    37681 cacatttggt attgaccgtg ctatgaagga attccactat gacaaaaagg aagtggtcat
    37741 ggttggcgac cagctcatga cagatatacg agcagcccac cgtgcaggga ttcggtcaat
    37801 tttagtcaaa cccttggtcc aacatgactc aatcaaaacg cagattaacc gaactcgtga
    37861 gcgtcgtgtt atgagaaaaa tcactgaaaa gtacggaccg attacatata aaaaaggaat
    37921 ttaactatgg aagaaattct ctgtattggt tgtggagcaa ccattcagac gacagataaa
    37981 gctggtcttg gttttacccc ccagtcggca cttgaaaaag gtttggagac tggcgaagtc
    38041 tattgccaac gctgtttccg tctccgccac tacaatgaaa tcacagatgt ccagttgacg
    38101 aacgatgatt tcctcaagct cttgcacgag gtgggagaca gtgatgcctt agtggtcaat
    38161 gtcattgata tctttgattt taatggatct gtcatcccag gtttaccacg tttcgtctcg
    38221 ggcaatgatg tcctcttggt aggaaataaa aaagatatcc ttcctaagtc agttaagtct
    38281 ggtaagatta gccagtggct catgaaacgt gcccatgaag aaggtcttcg tccagtcgat
    38341 gtggtcctaa cttcagcaca aaataaacat gccattaagg aagtcattga caagattgaa
    38401 cactaccgta agggccgcga tgtctatgtg gtcggtgtga ccaacgttgg aaaatcaact
    38461 ctaatcaatg ctattatcca agaaatcacg ggtgatcaga atgtcatcac tacttcacgc
    38521 ttcccaggta caaccttgga caaaatagag attccgcttg acgacggatc ttatatttac
    38581 gatacgccgg gaattatcca ccgccaccag atggctcact acttgacggc caaaaacctc
    38641 aagtatgtca gtcctaaaaa ggaaatcaag cctaagacct atcagcttaa tcctgagcaa
    38701 accctatttt taggtggttt gggacgcttt gactttatag caggagaaaa gcaaggattt
    38761 actgctttct ttgataatga actcaaactc catcgtagca agtttgaagg agctagtgct
    38821 ttctacgata agcacctggg aactcttctg acaccaccaa atagcaagga aaaagaagat
    38881 ttcccaaggc tagtccagca tgtctttacc attaaagata agacagacct agtcatctca
    38941 ggcctaggct ggattcgtgt aacaggcata gcaaaagtcg ccgtctgggc accagaaggc
    39001 gtcgccgtcg tcacacgaaa agcaattatt taaaacaaaa tcgctgagcg aacaaagtga
    39061 gctcatatag cgatagttat tgccgtggtg tgattgccaa tctgtagatt ggcaaggggc
    39121 acaattgaga ccaaggctca attgtgaggt caggaaatcc atttttcaaa gatgaaatct
    39181 ttggaaaatt agttccgacc gtccctcacc acctaaaata actatccaaa aacaaggaag
    39241 aaaattatgt cattaacatc aaaacaacgt gccttcctca acagccaggc acacaccctc
    39301 aaacctatca tccaaatcgg gaaaaatgga ctcaacgacc aaatcaaaac cagcgtccgt
    39361 caagctcttg atgcgcgtga attaatcaag gttactctct tacaaaacac agatgaaaat
    39421 atccacgaag tagctgaaat tttggaagaa gaaatcggtg tggatacagt ccaaaaaata
    39481 ggacgcatct tgattttgtt taaacaatct agcaagaaag aaaatcgcaa gatttctaag
    39541 aaagtcaaag aaatctaaga ccgaaactcc aaataactgt ttttatagag aaataaaggg
    39601 gactagccta tgacaatcga actattgact ccctttacca aggtagagtt ggagccagaa
    39661 atcaaggaga aaaaacgcaa acaagttggg attttagggg ggaattttaa ccctgttcac
    39721 aatgcccatc tcattgttgc ggatcaagta cggcaacagt tgggactgga tcaagttctt
    39781 ctcatgcctg aataccaacc tcctcacgtt gataaaaagg aaaccatccc tgaacaccat
    39841 cgtctcaaga tgcttgagtt ggcaattgag gggattgacg gcctagtcat tgaaaccatt
    39901 gagttggagc gcaagggtat ttcctacacc tacgacacca tgaaaatctt gacagagcaa
    39961 catccagata cggattatta ctttatcatc ggtgccgaca tggttgacta tctgcctaag
    40021 tggtaccgaa ttgatgaact ggttgacatg gttcagtttg tgggggttca gcgtccacgc
    40081 tacaaggcag ggacttccta tccagttatc tgggtggacg taccgctcat ggatatctcg
    40141 tccagcatgg tgcgggactt cattgcccaa ggtcggaaac ccaactttct cctacctcag
    40201 ccagtgctag actacatcga gaaggagggg ctctactgat gtcctatcaa gactatatca
    40261 actgctcccg tgaggccttg ttggaaaaaa tggcagagct tctacctgag aaacgtctaa
    40321 cccattgtct aggtgtggag cgtgccgcta tggagttagc tcagcgcttt ggtgtagatg
    40381 ttgagaaagc aagtctagca ggtcttcttc atgactatgc taaaaagttg tcagatcagg
    40441 aatttctaga cttgattgac cgttatcagc tagatttcga cctcaaaaac tggggtaata
    40501 atgtctggca tggtatggtc ggaatttaca aaattcagga agatttggat ttgcatgatt
    40561 cagaaatcct gcgagccatt gaagtccata cagtcggtgc tggtcaaatg acagacctag
    40621 ataaggtcat ctacgtcgca gactatatcg agcacaatcg agcctttcct ggagtagatg
    40681 tggcgcgtga gattgcaagt ctatcgctca ataaggcggt ggcctacgaa acagctcgta
    40741 ccgtggagta tctagctcat cagggattcc ccatctatcc ccaaaccctt gaaacctata
    40801 acgcctttgt gcactatttg aaagaggact aaatgaagac ggcttttata atcattgatg
    40861 ttcagaatgt tttagtagaa actgggttcc agacaaaaag tctattggaa aaaatttctt
    40921 atttacaaaa ccaggctaga agcaagaata ttgaaattat ctatgttcaa catattgaga
    40981 attctgaagc tcaaacatca gaagattggc agttatctgc gcttttaaat cgaaaacctg
    41041 ctgaaaaggt ctttcagaag aagtataaca gtattttcaa agaaactggc ttaaaagaat
    41101 acttggataa acaggggatt gaaaaattag ttttatgtgg tatgcagaca gaatattgtg
    41161 tggatacctc tgtcaaggtt gcctttgaat atggctatca gcttattgtt ccagaaggtg
    41221 ctgtcacaac ctttgatggg gatgacattc cagcagaaac gattaatgaa ttttatgagg
    41281 acatttggga ggagtgcttt gcagatgttc tagattacaa acatattttc taaaaagagg
    41341 attaaatgaa cgaaaaagaa ttactagaac tagtcgtgaa agcggctgat gagaaacgtg
    41401 cggaggatat cctcgcactt gatgtacaag atttgactag tgtgacggac tactttgtca
    41461 tcactagctc aatgaatagc cgtcagttgg acgctatcgc agctaatatc cgtgaaaaag
    41521 tagctcaagc aggctttaaa ggtagccata tcgaaggcga tgcagctgga ggctgggtct
    41581 tactggacct cggtgctgtt gtcgtgcata tcttttcaga agaaatgcgt gcccattata
    41641 atctagagaa gctatggcat gaggcgaatt cagtagatat ttcagaagct cttgcttaga
    41701 agatgaactc agttgtagtc aactgggttt ctttgcttat tttagaaaaa ttgatagaaa
    41761 ggtaaagggc tagtggtgtt taccatggag ctcttagtat catgattatg gcgacttatg
    41821 aaacctttgc ggcggtctat gatgcggtca tggacgatag tttatacgac aaatggacga
    41881 atttttctct gcgtcatttg cctaagacca aggagagaaa gaaactcttg gaattggctt
    41941 gtgggacagg aattcaatca gtgcgcttct ctcaggctgg ttttgatgtg actggacttg
    42001 acttgagtgc ggatatgttg aagattgcgg agaagagagc aacttcagcc aagcaaaaga
    42061 ttgcttttat agaaggtaat atgctgaatt tgtccaaggc agggaaatac gattttgtca
    42121 cgtgttattc ggactctatc tgctatatgc aggatgaggt ggaagtaggg gacgtcttta
    42181 aggacgtgta caatgcgctg aatgaagagg gagttttcat ctttgacgtg cactcgacct
    42241 accagacaga tgaagtattc cctggctatt cctaccatga aaatgcggaa gattttgcca
    42301 tgctttggga tacatatgag gacgaagttc ctcactccat cgtccatgag ctgactttct
    42361 ttatcaagga ggctgatggt tcctttagtc gccacgatga agtacatgag gagaggacct
    42421 atgagatctt gacctatgag atcttgctgg aacaggctgg attcaagtcc ttcaaactct
    42481 atgcagactt tgaggataag gagccaacag aaactagcac ccgttggttt tttgtggcgc
    42541 agaagtagga gattagcatg accataacag gtattatcgc ggagttcaat ccttttcata
    42601 atggccataa atacctgctg gatcaggcag agggactgaa aattgttgcc atgtcaggga
    42661 atttcatgca gcgtggagag cctgctattg tggataagtg gacaagggcc cagatggcgc
    42721 tggaaaatgg cgcagacttg gtagtggaat tgcccttttt agtcagtgtt caggcagctg
    42781 atttctttgg tcaaggagct gtggatatct tggatcgctt gggcattgat agtctagttt
    42841 ttgggacaga ggaagttctg gattaccaga aaatcgctga cttatacaca gagaaaggtg
    42901 ctgagatgga gaaatttgtg aaaaatctgc ctgattccct ttcctatccc cagaaaaccc
    42961 aagctatgtg gaaggaattt gctggtcttg atttttcagg taataccccc aatcatgttc
    43021 ttgctctggc ctatgcaaag gcggttgcag gacgaaatat caagctgcat ccgattcagc
    43081 gtcagggggc aggttaccat tctgtgaata aagatgtgga ctttgcctcg gcgacagccc
    43141 tccgtcaaca tcagaaggac caagatttct tagaacgttt tatgccttct gttgccctat
    43201 ttgagcaggc cagtaaggtg atctgggaag actattttcc cttgctccgc tatcaaatct
    43261 tgtcaaatcc cgacctaacc accatctatc aggtcaatca agaaatggct gtgcgcatta
    43321 aagaagctat taaaacagcc cagtctgtgg aagaattggt cgagttagtg actaccaaac
    43381 gttacaccaa ggcgcgtgtc agacgcctat tgacctatat tttggtacag gctagagaaa
    43441 atgtcttgcc agaagccatt catgtccttg gatttactga aaaaggcagg caacatctca
    43501 agtctctgaa aggacaggtc aatctagtca gccgaattgg caaagaacct tgggatgcta
    43561 tgactcaaaa ggttgaccag atttaccaac taggaaagcc aagtatagca gagcaaaatt
    43621 ttggcagagt gccgattaga atagaaacaa actaagtcta ctgaaaggta ggctttttta
    43681 ttgtagaaat tttagataac aaattgaaga taaagttttt ggaaaatgat aaactcccta
    43741 atacagaaga caaaaagtca ataaagaaaa ttagtatatg aaccttaatc tttatctctg
    43801 aatccgcttt atgcttgtta ttttgtggta taatgaagag aactggttat attaataatc
    43861 ataaattgaa tataaaagac aaataaattt ttatatttat aaaccatgat aaacttttgt
    43921 ttaagattat gtaataaaaa agaagattta taaggataat ttgtatttat gtagtacaag
    43981 ctaatgtagg atagttaaaa tatggaagaa aattataatt tatctataac tcaaataaag
    44041 aattctatta aagaaaattc cttagttttg tttgttggtg caggaatatc agctaattct
    44101 aatctaccaa cttggggaga attgattcaa tcattaaaaa aagaattgaa cataccagaa
    44161 gaaagaacag atagtccact gagaattgct cagtattatt atgatacttt tgggaaaaat
    44221 cagtacacaa agaagataga agaaattttc tttaagaagg gattgagtaa accaaatgag
    44281 ttacataaat taatagaaaa aattgcacca aaacatatta ttacgacaaa ctatgattca
    44341 cttctggaga gtcaatttga aagtggcttg ttaaagtaca atgtagtcgc tgaggataaa
    44401 gacatccctt atacgagttc ggaaagatac ttgattaaaa tgcatggtga cttcagtaag
    44461 aaaaatattg ttttgaaaga agatgattat ttagactatc atttgaactt cccaatgatt
    44521 tctactttaa tccagtcatt gataatgaat catactctat tgtttgtggg gtattctcta
    44581 agtgattcga cttttaattc aatttttaga atgattcaaa atacatttaa attggatgct
    44641 aaaaatgctt atttttatac tcccgaggaa ccgtctatga tcattcgaga gtattataag
    44701 aagcaaggaa ttttcattat ctctaatgaa gagaatctag gtcaggagac atcagaaaaa
    44761 cagaacaaat tgtattgcag gacaaaagat tttttagagg ttctatcaga aaaccgaagt
    44821 caagatgtaa ataatgctga tgatttatgg aatcaactgg cttttttaga tagacttagt
    44881 tttattgatg cgaaagattt ttctagatat tctgatttaa agaaaagggc tttaaactgg
    44941 gatgatgagt attgctggtt tggaaatgat caattaagat ttgaaattga tggtcatgaa
    45001 gaattacgaa ttatggtatc taaaaaatct ttattaaatc gctttctaga tatggagatt
    45061 ggtgagccta gggatttaaa ggggaatcga ttcttaagta aggcttttaa gttgtatgaa
    45121 gaaaaacaat attctttagc aaaagcaaaa tttagagaac tagctaatat agcatttcgt
    45181 cagaaagact attttaattt cttagtttgt gaatttaatt ttcagcaaat tcaaataatt
    45241 gatagatacg aaaaaacacc tagttatgca gagccacttt atgatggaga attaagcgaa
    45301 ttaacagaac aaattcttaa ctcggttaca ggagatgaga aaaagattat agaatttttt
    45361 agagattcaa tccttaactt caatttttta tatagaaaat tagaaactat taatgaatta
    45421 tttgatgaaa ttcgtgaaga gcatgaaagc tatagaagag gaggatggtc tgctaataat
    45481 catctattta atgcggagtt tacagtaaaa aatctttata actttttaaa attaaattgt
    45541 ttatgtgttg aacattataa gatttataaa tcaatcatta atagatattt agaaatatta
    45601 ttactcagtt atgataattc atatgtaaac cctgactcaa gtattttcga tagaacatct
    45661 tcttggctta aaaatcttga tttggatgat gttaaattaa ttcttccgaa tatagatttt
    45721 aaggttgtaa atttatattt tagaaactat tcatttggta aaataaaagt tactgaggaa
    45781 gcgaaagact acttgttgaa tcgaattact tatcttcaag aaagacttga aattactgaa
    45841 gatgaaaatc ttcgagagct taaaaatatg ctaatttttc ttccccttgt tgatgatatt
    45901 gacatagaaa aagtaataga aattttaaat aatcaaacac tgtattataa ttggagcgag
    45961 gaatttagga gaattattaa aattgtcctc gataatatgg atgttattga taaagattca
    46021 ttgaaatcta agataattgg gattgtaaat aaacatttaa atgaaatttt ggagaaaaat
    46081 ttttctttat ataattcagt gtatccgctc tattcacagt tactagaata ctgctcaact
    46141 gatcaggaaa ctgcaataat agtactcgaa aaatttaata cagatatttt aagaataaaa
    46201 tataaaaatg atgatataaa aaatatcata gaatattctg acttgatatg tcacttattt
    46261 aagtattttg aaaaggatat taaagatgac attttagata ctctaaaagt ttatgaagaa
    46321 tcagaaaata ttatttacca taaagtaatt gatttgatga gttataatgt ctatgatttt
    46381 cctcagatac aaaataaaat ctaccattat ttgattaaaa gaattaatga taaaagagtt
    46441 gagggggtta aaactttccc agacccaaga gaaaagtctg tatcagattt atacaactta
    46501 agtagaaaag gatatttttc tgattttgag attttaaaag atattgaaga agatattcga
    46561 ggactttatc ctgaagtaga ttggacctgg ttccatgata gaagtgatga tgttatccat
    46621 cgtctactag aacatagaac tcccaataat attaaaactt atttttcaaa aaatgaagaa
    46681 gataataaat tgattaatga gtatatttta aaagctttcg atgaggataa attaatactt
    46741 aagaaataaa ttgatacaac taaataaaaa agttaattta tgacaaattt gatcttgaag
    46801 ataagctgtg atttcctaaa gtgaattttc aaagacttga aagcaaaatg tttgaatcta
    46861 gtggaacact atttggcaca acaatagaaa atccatagcg gtagaaattc ggtggaactt
    46921 tttgatagcg gcactgactt atctccttaa aaaaccaagg aagtgtaatc ctaaaattca
    46981 gactaatttc cccaaaacat attctatttt aggtttgtga aaatcacttt tttatggtag
    47041 aatgtaaaag aatgtatgtc attcggaata acaataaaat gaggtaaaaa catggagatc
    47101 atgtcgcttg cgattgctgt ttttgccgtc atcattggtt tagtcattgg atatgtcagc
    47161 atctcagcta agatgaaatc atctcaggaa gctgcggagt tgatgctttt aaatgctgaa
    47221 caagaagcaa ctaatttacg tggacaagct gagcgtgaag cggatttact tgttaatgaa
    47281 gctaaacgtg aaagcaagtc tcttaaaaaa gaagcactat tggaggccaa agaagaagcc
    47341 agaaaatacc gtgaagaagt ggacgctgaa ttcaaatcag aacgtcaaga actcaaacaa
    47401 atcgaaagtc gtttgacaga gagagctact agccttgacc gtaaggacga caatttgacg
    47461 agtaaagaac aaacacttga acaaaaagaa caaagtattt ctgatagagc gaaaaacctt
    47521 gatgcgcgtg aagagcaatt agaggaagtc gaaagacaaa aagaagcaga actagagcgt
    47581 attggtgctc tgtctcaggc agaagcacga gatattatct tggctcagac agaggaaaac
    47641 ttgaccaggg agattgccag tcgcattcgc gaagctgagc aagaggtcaa ggaacgttct
    47701 gacaaaatgg ccaaggatat cttggttcaa gctatgcaac gtatcgctgg tgaatatgta
    47761 gcggagtcaa caaactcaac agttcatctg ccagacgata ctatgaaggg acgcattatt
    47821 ggtcgtgaag gtcgtaacat tcgtaccttt gaaagtttga caggggtcga tgtgattatc
    47881 gacgatacac cagaagtggt gaccttgtca ggatttgatc cgattcgtcg tgagattgcc
    47941 cgtatgacta tggaaatgtt gctcaaagat ggtcgtatac atccagctcg tatcgaagag
    48001 ttggttgaga aaaaccgtca agagattgac aataagattc gtgaatacgg tgaggctgct
    48061 gcctatgaaa ttggtgcgcc aaaccttcat ccagacttga tgaagattat gggacgtttg
    48121 cagttccgta cttcatatgg acaaaatgtt ttgcgccatt cgattgaggt tgctaagttg
    48181 gctggtatca tggcgagcga acttggtgaa aatgcggctc ttgcccgtcg tgctggattc
    48241 cttcacgata tcgggaaagc cattgaccat gaggttgaag gtagccacgt tgaaatcggt
    48301 atggaattgg cccgtaagta caaggaaccc ccagttgtgg tgaatacgat tgctagtcac
    48361 cacggagatg ttgaagctga gagcgtgata gcagttatcg tcgctgcagc agatgccttg
    48421 agcgcagccc gtccaggtgc tcgtagtgag tctcttgaaa gctacatcaa gcgtctccat
    48481 gatttggaag aaattgctaa cggctttgaa ggagtgcaaa ctagctttgc ccttcaagca
    48541 ggacgtgaaa ttcgtatcat ggtcaatcca ggaaaaatca aggacgacaa agtcacaatc
    48601 ttggctcaca aagttcgtaa gaaaattgaa aacaatctcg attatccagg aaatatcaag
    48661 gtaaccgtga ttcgcgagct tcgtgcagta gattatgcta aataaataag aaagagcagt
    48721 tgaaaaatta ctgctttttt gttacactag atagaaagac tgtaaaggat aatctggctt
    48781 tttgccatta ttctagagaa atgttatttc acagattgac taaaaggaga cacaatggca
    48841 gaccgaggct tactaatcgt tttttctggt ccttcagggg ttggaaaagg aacggttaga
    48901 agagagattt ttgagagttc tgaaaaccaa tttcaatatt ctgtatcgat gacgacacgc
    48961 gcacaacgtc ctggagaagt ggacggtgtt gactatttct tccgtactcg tgaagaattt
    49021 gaagagctga ttcgtcaagg acagatgttg gaatacgcag aatatgtcgg caactactat
    49081 ggaactcctc tgacctatgt caatgaaacc ttggacaagg gaatcgatgt tttccttgaa
    49141 attgaagttc agggtgctct tcaggtcaag aaaaaggttc cagatgctgt ctttatcttc
    49201 ctgacaccac cagatttgga tgaattgcaa gatcgcttgg taggtcgtgg aacagatagt
    49261 gcagaagtga ttgcccaacg aatcgaaaag gccaaggaag aaattgccct catgcgtgag
    49321 tatgattatg cgattgtcaa cgatcaggtg cccctagctg ctgaacgtgt caaatgtgtg
    49381 attgaagcag aacacttctg tgtggatcgt gtcattggtc actatcagga gatgttacca
    49441 aaatctccaa ctacccgata aaatttagaa aataggtaca agcaaatgat gttaaaaccc
    49501 tctattgata ccttgctcga caaggttcct tcaaaatatt cactcgtaat cttggaagca
    49561 aaacgtgccc acgaattgga agcaggtgcc ccagcaactc aaggtttcaa gtctgaaaaa
    49621 tcaactcttc gcgctttaga agaaatcgaa tcaggaaacg ttacaattca cccagatcca
    49681 gaaggaaaac gtgaagcagt gcgtcgccgt atcgaagaag agaaacgccg caaagaagaa
    49741 gaagaaaaga aaatcaaaga gcaaattgct aaagaaaaag aagatggtga aaaaatttaa
    49801 ggttgggggg actcaatctt attttttcta ttgcaagaat gtactgacaa ggaggaggtg
    49861 agaagatggc cctagctaag attatcgtag atgtgccttt gatgcagacg gaccagccct
    49921 atagttacag gattccggag gaatttgagg gaatgctgga agttgggatg cgggttcatg
    49981 taccttttgg taagggtaat cgcctgattc aagggattgt tcttggtttg gagtcccaat
    50041 cagatggaga agagatggag caagatttaa aagatattgc agaggtgctg gatttttctc
    50101 ctgttctcac gccagaacaa ctctggctgg ctgaggagtt acgcaaatct gtcttctcct
    50161 acaaaatctc tatcctcaag accatgcttc caggatttct gaattctagc tatgacaaga
    50221 ttctctatcc tctggaaggc ttgagtcagg aagaacgagt acgcctgttt ggttcagaag
    50281 attcgctagc cttttcttca ctagaccttg ccaagcaagc tgaaatgatg cgtttgacta
    50341 gaaaaggcct gcttggtctg gaatatcagg cagtcgatca aaagaaggtc aagacccagt
    50401 cttggtatga ggttgaccat gcccaattag aaggtgttga gatttctaca cgtgccaaga
    50461 aaaagttgga actgagagat tatctgctgt ctcatccaga gagcgcttcc ttggctagct
    50521 tgttagagtc ctactcgcga gagcaagtca acttctttgt ggatcaaggt gctgttacca
    50581 tagtccaaaa ggaagttcaa cgctcggctg cttattttga aggaattgaa gcaagtagac
    50641 ctttggagtt aaatccagaa caaagacagg cgcgtgatgc ggttgtgagt tctattggca
    50701 gttctcaacc tccctttcta cttcaaggga ttacaggaag tgggaagacc gaggtttact
    50761 tgcagattat ccaaggtgcc ctggataagg gcaagacagc tattttgctg gtacctgaga
    50821 tttccttgac tcctcagatg accgagcgtt ttatagcacg ttttggggac aaggtagcca
    50881 ttcttcactc aggattatcc aatggtgaaa agtatgatga atggcgcaag gtggagcgtg
    50941 gcgatgccca agttgttgtt ggtgccagat ctgctatctt tgctcctctg aaaaatctgg
    51001 gtgtcatgat tattgatgaa gagcatgaag cggcttataa gcaggacagc aatccccgtt
    51061 accatgccag agaggtagct attttacggg ctcagtataa tcaagcaact ctggtacttg
    51121 gatctgcaac gccgagctta gagagccggg cacgtgctgg caaaggcgtc tatcaacact
    51181 tacgtctaac ccaacgtgcc aatcctttgg ctacaatccc tgaggttcaa gtgattgact
    51241 ttcgagacta tatcggacaa aatgagacgt caaactttac gcctcctttg ctagaggcta
    51301 tccaagaccg tctggttaaa aaagagcagg tggttctcat gctcaatcgc cgtggttatt
    51361 ctagctttgt catgtgtcgg gagtgtggga cggtggatac ttgtcccaac tgcgatattt
    51421 ctctgacctt gcatatggat accaagacta tgaactgcca ttattgtggt ttctcgaagg
    51481 atattcctca ggtctgtcct aactgtaaga gccacagtat tcgttactat gggacgggaa
    51541 ctcagaaggc ttatgatgag ctagcagaac tctttcccca agctcgcatt tttaggatgg
    51601 atgtggatac gactcgaaag aaaggcagtc accaagcctt gcttgaccag tttgggcgag
    51661 gggaagcgga tattttactt ggtactcaga tgattgcaaa gggtttggat tttcccaatg
    51721 ttaccctagt cggagttcta aatgcggata cggccttgaa tctgcctgat ttccgttctt
    51781 ctgagagaac cttccagctc ttgactcagg tagcaggtcg agcaggtcgg gctgaaaaag
    51841 caggtcaagt cttgatacag tcctacaatt cgcagcacta tgctattcga tttgccaagg
    51901 atcaagatta cgaaggcttt tatgcctatg aaatgggaat cagacgacaa ctcggctatc
    51961 caccttacta tttcacgatt ggtattaccc tttctcacaa gaaagaagaa gaggttttca
    52021 aacgtgccta tgaagtcatg aacattttgc ggtcaggctt gtcagagacc agtcccattc
    52081 tggggccaac gccaaaaccg attgcccgta cccacaacct ctatcattac cagattttaa
    52141 ttaaataccg tttagaagat gagctggggc cgaccctcaa ccaggtcttg gccttgactc
    52201 aagaacggga aaatagtgag ctccgtctca gcattgacca tgagccgcag caatttttat
    52261 aagaaggaga agatatgaca aaactaatct ttatggggac ccccgacttt tcagcaacag
    52321 tcttaaaagg acttttgaca gatgaccgtt acgaaattct agccgttgtg acccagccag
    52381 accgtgctgt tggtcgtaaa aaagttatcc aagaaacccc agtcaagcag gctgccaagg
    52441 aagcaggact atctatctac caacctgaaa aattatctgg aagtccagag atggaagaac
    52501 ttatgaagct aggagcagat ggaattgtga ctgctgcttt tgggcagttt ctcccaagca
    52561 aactccttga tagcatggac tttgctgtca acgttcatgc ctccctcctt cctagacacc
    52621 gtggtggtgc gcctatccat tatgccttga ttcaagggga tgaggaagct ggtgtgacca
    52681 tcatggaaat ggttaaggaa atggatgcag gagatatgat ttctcgtcgc agcattccga
    52741 tcacagatga ggacaatgtt ggcaccttgt ttgaaaaatt ggcgctagtt ggtcgtgatt
    52801 tgcttttgga cactctgcct gcctatattg ctggtgatat caaacctgaa ccgcaggata
    52861 cgagtcaggt taccttctct ccaaatataa agccagagga agaaaaactg gactggaaca
    52921 aaaccaatcg tcaactcttt aaccaaattc gtggaatgaa cccctggcct gttgcccata
    52981 ctttccttaa gggcgaccgc tttaagattt atgaagccct accagtagaa ggtcagggaa
    53041 atccaggtga gattctctct atcggcaaga aagaattgat tgtcgcaacg gctgaagggg
    53101 ctctatccct caaacaagtg cagccagctg gtaagcctaa gatggacatt gcttccttcc
    53161 tcaacggagt tggacgtaca ttgactgtag gagaacgatt tggtgactaa agtagaaacg
    53221 gctagaagtt tagctctagc agtgctagag gatgtttttg tgaaccaagc atattcaaat
    53281 atcgccttaa ataaacacct caaggggagt cagctctctg cagcagacaa gggcttagtg
    53341 accgagctag tctatggaac ggtagcccgt aaactgactc tggaatggta cctatcccac
    53401 tttatcgaag acagagacca gttagacagc tggctctatg tccttcttct catgagtgtc
    53461 taccaactcc gctatttgga caagattcca gatcatgctg tggtcaatga agcagtggaa
    53521 ttggccaaac tccgtaaaaa aggcagtgaa aaattggtca acgctgtcct tcgccgtatc
    53581 ttgcgtgaag gctggccaga tattgctaac atcaagcgaa aaaacaagcg tgactccatt
    53641 gcctattctc tcccagtttg gctagttacc aaactcaagg aagaatacgg agaggagaga
    53701 gcaaaagcca tctttgaaag cttgttagtg cgaaacaaag ctagtattcg tgtaacagac
    53761 ctaagtcgaa aagaggaaat ccaagccttg ttggaggcga atagttccct tttagcaacc
    53821 actggtctgg ttaaggagca agggcatttt gcagggcata atttgtttgc ggatggagcc
    53881 attaccatcc aagatgagtc cagtcagctg gttgctccga cgcttgattt acaaggtgat
    53941 gagcgagtgc ttgatgcctg tgcggctcca ggtgggaaaa cagcccatat agcctcttat
    54001 cttacgacag gtcaggttac tgctctggac ttgtacgacc acaagttgga tttaattcaa
    54061 gaaaatgccc aacgtctggg agttgaagat cgggttcaaa ctcaaaaatt ggatgccaga
    54121 aaggtgcatg agttttttga ccaggattcc tttgataaga ttttggtgga tgctccttgt
    54181 tcaggaatcg gtcttttgcg ccgaaaacca gatatcaaat acaataaaga aacggcagat
    54241 ttcgcgtcct tgcaggaaat tcagttagaa atattaggta gtgtttgtca aatactaggc
    54301 aaaggtggta taataactta tagcacctgc actatcgtct cagaggagaa ttttcaagtc
    54361 gttaaggcct ttttagagag tcatcccgag ttcgagcagg taaaactaga acatgaatgt
    54421 aaggatatca tgaaagacgg ctgtatcctc attacacctg aattgtatgg aagtgatgga
    54481 ttcttcatca gtcaatttcg caagatatcg gattaggaag gaactgacac atggaaattt
    54541 cattattaac agatgttggt cagaaacgaa caaataacca agactatgtc aaccactatg
    54601 tcaatagagc tggacgtacc atgattattt tagctgatgg gatgggaggt catcgtgcag
    54661 ggaatatcgc tagtgaaatg gcggtcacag acctgggtgt agcttgggtt gatacccaga
    54721 tcgatacagt caatgaagtg cgtgaatggt tcgcccatta cctagaaatt gaaaatcaaa
    54781 agattcacca gcttggtcag gatgaagctt acagaggcat gggaactact ttggaagtcc
    54841 ttgctattat tgataatcag gctatctatg ctcatattgg tgattcgcgt atcggcttga
    54901 ttcgtggaga agaataccat cagttgacga gcgatcattc cttggttaat gaattgctca
    54961 aggctggtca attgacacca gaagaggcag aagctcatcc gcaaaaaaat attatcaccc
    55021 agtctattgg gcaaaaagat gaaattcagc ctgattttgg gacagttatc cttgagtcag
    55081 gtgactatct cttgctcaat agtgacggct tgaccaacat gatttcaggc agtgagattc
    55141 gtgatattgt aaccagtgat attcctttag cagataaaac ggagacactt gttcgttttg
    55201 ctaacaatgc aggaggttta gacaacatta cggttgccct tgtttctatg aacgaggagg
    55261 atgcagaatg atccaaatcg gcaagatttt tgccggacgc tatcggattg tcaaacagat
    55321 tggtcgagga ggtatggcgg atgtctacct agccaaagac ttaatcttag atggggaaga
    55381 agtggcagtg aaggttctga ggaccaacta ccagacggac ccgatagctg tagctcgttt
    55441 tcagcgtgaa gcgagagcta tggcagatct agaccatcct catatcgttc ggataacaga
    55501 tattggtgag gaagacggtc aacagtatct tgcaatggag tatgttgctg gactagacct
    55561 caaacgctat atcaaggaac attatcctct ttctaatgaa gaagcagtcc gtatcatggg
    55621 acaaattctc ttggctatgc gcttggccca tactcgagga attgttcaca gggacttgaa
    55681 acctcaaaat atccttttga caccagatgg gacggccaag gtcacagact ttgggattgc
    55741 tgtagccttt gcagagacaa gtctgaccca gactaactcg atgttgggct cagttcatta
    55801 cttgtcacca gagcaggcgc gtggttcgaa ggcgactgtg cagagtgata tctatgccat
    55861 ggggattatt ttctatgaga tgttgacagg ccatatccct tatgacgggg atagcgcggt
    55921 gaccattgcc ctccagcatt tccagaaacc cctgccgtcc gttattgcag aaaatccatc
    55981 tgtacctcag gctttagaaa atgttattat caaggcaact gctaaaaagt tgaccaatcg
    56041 ctaccgctcg gtttcagaga tgtatgtgga cttgtctagt agcttgtcct acaatcgtag
    56101 aaatgaaagt aagttaatct ttgatgaaac gagcaaggca gataccaaga ccttgccgaa
    56161 ggtttctcag agtaccttga catctattcc taaggttcaa gcgcagacag aacacaaatc
    56221 aatcaaaaac ccaagccagg ctgtgacaga ggaaacttac caaccacaag caccgaaaaa
    56281 acatagattt aagatgcgtt acctgatttt gttggccagc cttgtattgg tggcagcttc
    56341 tcttatttgg atactatcca gaactcctgc aaccattgcc attccagatg tggcaggtca
    56401 gacagttgca gaggccaagg caacgctcaa aaaagccaat tttgagattg gtgaggagaa
    56461 gacagaggct agtgaaaagg tggaagaagg gcggattatc cgtacagatc ctggcgctgg
    56521 aactggtcga aaagaaggaa cgaaaatcaa tctggttgtc tcatcaggca aacaatcctt
    56581 ccaaattagt aattatgtcg gccggaaatc ttctgatgtt atcgcggaat taaaagagaa
    56641 aaaagttcca gataatttga ttaaaattga ggaagaagag tcgaatgaga gtgaggctgg
    56701 aacggtcctg aagcaaagtc taccagaagg tacgacctat gacttgagca aggcaactca
    56761 aattgttttg acagtagcta aaaaagctac gacgattcaa ttagggaact atattggacg
    56821 gaactctaca gaagtaatct cagaactcaa gcagaagaag gttcctgaga atttgattaa
    56881 gatagaggaa gaagagtcca gcgaaagcga accaggaacg attatgaaac aaagtccagg
    56941 tgccggaacg acttatgatg tgagtaaacc tactcaaatt gtcttgacag tagctaaaaa
    57001 agttacaagt gttgccatgc cgagttacat tggttccagc ttggagttta ctaagaacaa
    57061 tttgattcaa attgttggga ttaaggaagc taatatagaa gttgtagaag tgacgacagc
    57121 gcctgcaggt agtgcagaag gcatggttgt tgaacaaagt cctagagcag gtgaaaaggt
    57181 agacctcaat aagactagag tcaagatttc aatctacaaa cctaaaacaa cttcagctac
    57241 tccttaaaag tagatggata atcaaaatga gtaatcaatc tttgtcatga tttcatggca
    57301 aagatttttt ttgagtccag atttgtgata gaatagaggg agttgataaa aggaggaaag
    57361 catggaagaa tcaaaagaat taaatgccgt cattgatgtg attatgctag cggggactat
    57421 tctccttaaa agtggctcag aaatccatcg tgtagaagat accatgattc gaatcgcgca
    57481 ttcgcagggg attgtggatt gcaatgtcct tgccatgcct gccgctatct ttttctctat
    57541 tgaaaatacc aatatttcgc gcatgaagcg cgtgacctcc tcttcttata acatcgaaaa
    57601 agtctgcgat gtgaaccaga tttctcgtca gctggttggg gggcagattg atttagaaac
    57661 agcctttaag caattgacgg ccttgcaagc tcaacccctt ccctatacta agttgcaggt
    57721 aactctggct gcgaccttta gtgctccttt cttttcagtt atgtttagcg gaaatatcta
    57781 cgacgcactt ggggcaggag tggcgacctt atttggtttt gccttttccc tctatgtgga
    57841 aaaatttatc cgaattccct ttgtgacagc ctttgctgga gcctttgtct ttgggataat
    57901 tgcccagttt tgggctcgct acacaggttt tccttcaacg gcagatttga ttatagctgg
    57961 tgcggtcatg ccgtttgtac caggtattgc cttgaccaat gcggtccgtg atattatgac
    58021 caaccacata aactctggta tgagtaagat gtttgaatcc ctgctcatta ccctcgcttt
    58081 aggggcagga acttctgtcg ccttggtatt ggtgaactaa tatgacacta acaacctttt
    58141 tattacaagc agtagcaagt tttcttgcca ttatcacttt tttaatcgta ctcaatgtgc
    58201 aacggtctat gctcttacct ggagggattt tgggcatgac tgtctggcta atctatctct
    58261 tgctcaagga accgaccaat gtcattgtag ctaccttcat tgcagccatt attggttctt
    58321 gtgtcagcca gattttaagt attctttata agacacctgc tgtggtcttt atcttggcca
    58381 ttttggcacc gctggttcca ggttatctct cctaccgaac aactgccttt tttgtgacag
    58441 gggactataa taaagcactg gcaagtgcga ccttggttgt catgttggct ttggtaatct
    58501 ctattggaat ggctagcgga acagtgattc tcagactgta tcattatata aaaacacatc
    58561 gagtatcgta gattttacag aaataaaaga attttctgaa aaatgagata aataaattaa
    58621 caacgctttc tatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
    58681 atccacgaaa gcaacttact ccgtcggagc caatgggttg aagtaactct tgttcaaagt
    58741 ggttttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
    58801 gaagtaaaaa tcaatcgccc taaaaaaaga attagcgaat tattctggta aaaagaaatg
    58861 ccacgctatg aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttgga
//
LOCUS       DAVBOM010000008        49378 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBOM010000008 DAVBOM010000000
VERSION     DAVBOM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.008"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(93..551)
                     /locus_tag="VQ878_000466"
     CDS             complement(93..551)
                     /locus_tag="VQ878_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET3094868.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(548..988)
                     /locus_tag="VQ878_000467"
     CDS             complement(548..988)
                     /locus_tag="VQ878_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3094869.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1194..3143
                     /gene="mutL"
                     /locus_tag="VQ878_000468"
     CDS             1194..3143
                     /gene="mutL"
                     /locus_tag="VQ878_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET3094870.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3468..3935)
                     /locus_tag="VQ878_000469"
     CDS             complement(3468..3935)
                     /locus_tag="VQ878_000469"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET3094871.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3936..5141)
                     /locus_tag="VQ878_000470"
     CDS             complement(3936..5141)
                     /locus_tag="VQ878_000470"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET3094872.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ878_000471"
     CDS             complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ878_000471"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET3094873.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ878_000472"
     CDS             complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ878_000472"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET3094874.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7015..7129)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ878_000473"
     CDS             7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ878_000473"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET3094875.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7889..8452
                     /locus_tag="VQ878_000474"
     CDS             7889..8452
                     /locus_tag="VQ878_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET3094876.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8449..9126
                     /locus_tag="VQ878_000475"
     CDS             8449..9126
                     /locus_tag="VQ878_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3094877.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9263..10294)
                     /locus_tag="VQ878_000476"
     CDS             complement(9263..10294)
                     /locus_tag="VQ878_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET3094878.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(10549..11232)
                     /locus_tag="VQ878_000477"
     CDS             complement(10549..11232)
                     /locus_tag="VQ878_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET3094879.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11244..12188)
                     /locus_tag="VQ878_000478"
     CDS             complement(11244..12188)
                     /locus_tag="VQ878_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3094880.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ878_000479"
     CDS             12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ878_000479"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET3094881.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15144..16205
                     /locus_tag="VQ878_000480"
     CDS             15144..16205
                     /locus_tag="VQ878_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3094882.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALIDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16337..16735
                     /gene="spx"
                     /locus_tag="VQ878_000481"
     CDS             16337..16735
                     /gene="spx"
                     /locus_tag="VQ878_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET3094883.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            16801..17370
                     /locus_tag="VQ878_000482"
     CDS             16801..17370
                     /locus_tag="VQ878_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3094884.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17457..17723
                     /locus_tag="VQ878_000483"
     CDS             17457..17723
                     /locus_tag="VQ878_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET3094885.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ878_000484"
     CDS             17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ878_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET3094886.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18162..18467
                     /locus_tag="VQ878_000485"
     CDS             18162..18467
                     /locus_tag="VQ878_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET3094887.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18773..20023
                     /locus_tag="VQ878_000486"
     CDS             18773..20023
                     /locus_tag="VQ878_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3094888.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20020..20562
                     /locus_tag="VQ878_000487"
     CDS             20020..20562
                     /locus_tag="VQ878_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET3094889.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            20708..22240
                     /gene="cls"
                     /locus_tag="VQ878_000488"
     CDS             20708..22240
                     /gene="cls"
                     /locus_tag="VQ878_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET3094890.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22318..22461
                     /locus_tag="VQ878_000489"
     CDS             22318..22461
                     /locus_tag="VQ878_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094891.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            22498..24036
                     /locus_tag="VQ878_000490"
     CDS             22498..24036
                     /locus_tag="VQ878_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3094892.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVGLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGEAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ878_000491"
     CDS             24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ878_000491"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET3094893.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26375..26515
                     /locus_tag="VQ878_000492"
     CDS             26375..26515
                     /locus_tag="VQ878_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094894.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26559..27065
                     /locus_tag="VQ878_000493"
     CDS             26559..27065
                     /locus_tag="VQ878_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3094895.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ878_000494"
     CDS             27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ878_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET3094896.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLGQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27645..28262
                     /locus_tag="VQ878_000495"
     CDS             27645..28262
                     /locus_tag="VQ878_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET3094897.1"
                     /translation="MKKKGLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDIFALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ878_000496"
     CDS             28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ878_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET3094898.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29042..29668
                     /gene="rplC"
                     /locus_tag="VQ878_000497"
     CDS             29042..29668
                     /gene="rplC"
                     /locus_tag="VQ878_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET3094899.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29693..30316
                     /gene="rplD"
                     /locus_tag="VQ878_000498"
     CDS             29693..30316
                     /gene="rplD"
                     /locus_tag="VQ878_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET3094900.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30316..30612
                     /locus_tag="VQ878_000499"
     CDS             30316..30612
                     /locus_tag="VQ878_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET3094901.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30630..31463
                     /gene="rplB"
                     /locus_tag="VQ878_000500"
     CDS             30630..31463
                     /gene="rplB"
                     /locus_tag="VQ878_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET3094902.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ878_000501"
     CDS             31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ878_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET3094903.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            31860..32204
                     /gene="rplV"
                     /locus_tag="VQ878_000502"
     CDS             31860..32204
                     /gene="rplV"
                     /locus_tag="VQ878_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET3094904.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ878_000503"
     CDS             32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ878_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET3094905.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            32874..33287
                     /gene="rplP"
                     /locus_tag="VQ878_000504"
     CDS             32874..33287
                     /gene="rplP"
                     /locus_tag="VQ878_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET3094906.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33297..33503
                     /locus_tag="VQ878_000505"
     CDS             33297..33503
                     /locus_tag="VQ878_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET3094907.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ878_000506"
     CDS             33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ878_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET3094908.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            33814..34182
                     /gene="rplN"
                     /locus_tag="VQ878_000507"
     CDS             33814..34182
                     /gene="rplN"
                     /locus_tag="VQ878_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET3094909.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34260..34565
                     /gene="rplX"
                     /locus_tag="VQ878_000508"
     CDS             34260..34565
                     /gene="rplX"
                     /locus_tag="VQ878_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET3094910.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34589..35131
                     /gene="rplE"
                     /locus_tag="VQ878_000509"
     CDS             34589..35131
                     /gene="rplE"
                     /locus_tag="VQ878_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET3094911.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ878_000510"
     CDS             35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ878_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET3094912.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ878_000511"
     CDS             35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ878_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET3094913.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36293..36829
                     /gene="rplF"
                     /locus_tag="VQ878_000512"
     CDS             36293..36829
                     /gene="rplF"
                     /locus_tag="VQ878_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET3094914.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            36913..37269
                     /gene="rplR"
                     /locus_tag="VQ878_000513"
     CDS             36913..37269
                     /gene="rplR"
                     /locus_tag="VQ878_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET3094915.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ878_000514"
     CDS             37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ878_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET3094916.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ878_000515"
     CDS             37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ878_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET3094917.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38122..38562
                     /gene="rplO"
                     /locus_tag="VQ878_000516"
     CDS             38122..38562
                     /gene="rplO"
                     /locus_tag="VQ878_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET3094918.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38575..39885
                     /gene="secY"
                     /locus_tag="VQ878_000517"
     CDS             38575..39885
                     /gene="secY"
                     /locus_tag="VQ878_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET3094919.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40036..40674
                     /locus_tag="VQ878_000518"
     CDS             40036..40674
                     /locus_tag="VQ878_000518"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET3094920.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            40791..41009
                     /gene="infA"
                     /locus_tag="VQ878_000519"
     CDS             40791..41009
                     /gene="infA"
                     /locus_tag="VQ878_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET3094921.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ878_000520"
     CDS             41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ878_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET3094922.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ878_000521"
     CDS             41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ878_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET3094923.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ878_000522"
     CDS             41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ878_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET3094924.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41977..42912
                     /locus_tag="VQ878_000523"
     CDS             41977..42912
                     /locus_tag="VQ878_000523"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET3094925.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ878_000524"
     CDS             42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ878_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET3094926.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43575..43841
                     /locus_tag="VQ878_000525"
     CDS             43575..43841
                     /locus_tag="VQ878_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET3094927.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            43851..45188
                     /locus_tag="VQ878_000526"
     CDS             43851..45188
                     /locus_tag="VQ878_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET3094928.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45432..46124
                     /locus_tag="VQ878_000527"
     CDS             45432..46124
                     /locus_tag="VQ878_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3094929.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46227..47872)
                     /locus_tag="VQ878_000528"
                     /pseudo
     CDS             complement(46227..47872)
                     /locus_tag="VQ878_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(47862..48485)
                     /locus_tag="VQ878_000529"
     CDS             complement(47862..48485)
                     /locus_tag="VQ878_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3094930.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(48471..48593)
                     /locus_tag="VQ878_000530"
                     /pseudo
     CDS             complement(48471..48593)
                     /locus_tag="VQ878_000530"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(48570..48940)
                     /locus_tag="VQ878_000531"
                     /pseudo
     CDS             complement(48570..48940)
                     /locus_tag="VQ878_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(48953..49321)
                     /locus_tag="VQ878_000532"
     CDS             complement(48953..49321)
                     /locus_tag="VQ878_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3094931.1"
                     /translation="MTVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKSK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
BASE COUNT        14871 a         9321 c        10872 g        14314 t
ORIGIN      
        1 tcctgttctt atttgatttc actatagtaa ggtgcagcag gataaagaaa aaccgagaag
       61 tttctttctc ggatttgctt attatgaggt tcctattttc tatgctccaa gagttgattg
      121 atgtgatcta cttttttagc ctctctttta tagagaatag cccagatgat gagatagaca
      181 atcgcaaact cgataatgag ctggaggtag aaaatccagt ggaaagggaa ccaaccagca
      241 agagttgcta gtgggacaaa gccagccagc ataaggaaga aatgagtcag agtggcacga
      301 agcatgctcc agtcacggct gaataagcgg ttgccaaagt tgaagagcat accgatggct
      361 gcccagataa gtgtgcagta gagcaagacc agggcaccgt gaacctgatg ctgatccatc
      421 acttggccga tgagagagta gggatttagt ggtgcgtagg tatttggtgc ataaatgagt
      481 gaaaagagga tggagaggat gaggccgata agaacaccgg cagctgcatc gtgaaatact
      541 tgttttttca tagttctaat ttctccttga tggtttttag ataacggcgt gaagagtagg
      601 tgaagctttc gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc ttgaggtgag
      661 agatggaatc gatattgatg atttctgatt gggaaatttg gataaaattg gttggcaaga
      721 gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg gtttctgcta
      781 gaaccttccg attctcgata tagaagcgct gaatcttgcc aatctcaact agatagacct
      841 gatcatcgat tttccctttg attttttctc tttggtccag attttctgcg aactcgatga
      901 ctttctggac tttatctgtc ggctgaggtg cttggacaat cagcttttcc tcctcgtaag
      961 tctcactaat ctgtagttct actttcatag ttttctctcc ttttcagtta tacaaggttg
     1021 tgatcacttc ctgtatatcc ttattaaaca ctattttata gcccatggca aggaaccttg
     1081 tctatgtgga gggattgggc tcctatgtgg tggagctttt ctgttctttc tgaaatatgg
     1141 tataatagca ctaattaatt tctaggaaaa tagatacaga aaggggctga aagatgtctc
     1201 atattattga attgccagag atgctggcaa accaaatcgc agctggggag gtcattgaac
     1261 gtcctgccag tgtggttaaa gagttggtag aaaatgccat tgacgcgggc tctagtcaga
     1321 ttatcattga gattgaggaa gctggtctca agaaggttca aatcacggat aacggtcatg
     1381 gaattgccca cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa
     1441 atcaagcaga tctctttcgg attcggacgc ttggttttcg tggtgaagcc ttgccttcta
     1501 ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga tggtgctagt catggaacca
     1561 agttagtcgc gcgtgggggt gaagttgagg aagtcatccc agcgactagt cctgtgggaa
     1621 ccaaggtttg tgtggaggat ctctttttca acacgcctgc ccgtctcaag tatatgaaga
     1681 gccagcaagc ggagttgtct catatcattg atattgtcaa ccgtctgggc ttggcccatc
     1741 ctgagatttc ttttagcttg attagtgatg gcaaggaaat gacgcggaca gcagggactg
     1801 gtcaattgcg ccaagcaatc gcagggattt acggtttggt cagtgccaag aagatgattg
     1861 aaattgagaa ctctgaccta gatttcgaaa tttcaggttt tgtgtccttg cctgagttga
     1921 ctcgggctaa ccgcaattat atcagcctct tcatcaatgg tcgttatatc aagaacttcc
     1981 tgctcaatcg tgctattttg gatggtttcg gaagcaagct tatggttgga cgttttccac
     2041 tggctgtcat tcacatccat atcgaccctt atctagcgga tgtcaatgtg catccaacta
     2101 agcaagaggt gcggatttcc aaggaaaaag aactgatgac cctggtttca gaagctattg
     2161 caaatagtct caaggaacaa accttgattc cagatgcctt ggaaaatctt gccaaatcga
     2221 ccgtgcgcaa tcgtgagaag gtggatcaaa ctattctccc actcaaagaa aatacgctct
     2281 actatgagaa aactgagccg tcaagaccta gtcaaactga agtagctgat tatcaggtag
     2341 aattgactga tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg gaccgattga
     2401 ccaagccagc aaaactgcat tttgcagaga gaaagcctgc taactacgac cagctagacc
     2461 atccagagtt agatcttgct agcatcgata aggcttatga caaactggag cgagaagaag
     2521 catccagctt cccagagttg gagtttttcg gacaaatgca cgggacttat ctctttgccc
     2581 aagggcgaga tggactttac atcatagatc agcacgctgc tcaggaacgg gtcaagtacg
     2641 aggagtaccg tgaaagcatt ggcaatgttg accagagcca gcagcaactc ctagtgccct
     2701 atatctttga atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag
     2761 aggaagtggg cgtctttcta gcagagtacg gagaaaatca atttattcta cgtgaacatc
     2821 ctatttggat ggcagaagaa gagattgaat caggcatcta tgagatgtgc gacatgctcc
     2881 ttttgaccaa ggaagtttct atcaagaaat accgagcaga gttggctatc atgatgtctt
     2941 gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca ttcagctaga caactcctct
     3001 atcagctttc tcaatgtgac aatccctata actgtcctca cggacgtcct gttttggtgc
     3061 attttaccaa gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat cataccagtc
     3121 tccgtgagtt ggggaaatat taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag
     3181 aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta tgcgttttat catggaaata
     3241 gttacttcat gttttcctaa ttcttttcga aactcttttt aaaccacgtc agttttatca
     3301 gtaatctcaa aacagtgttt tgagctaatt ttgccagttt tgtctgtaac atcgaagttg
     3361 tgtttgacca ctctgcgact ggtttcctag tttgctctat gattttcaca gagtattaaa
     3421 ttgcgatttt gccaagtttc tttattcgtc taaaagtaga gtctgttcta tgcgtctaat
     3481 gtacgaatta ggttgaccat ttcaatagct ccttgtgcac actcagaacc cttatttcct
     3541 gctttagtgc cagctcgttc tatggcttgt tcaattgtat ctgtcgttag cacaccaaac
     3601 ataacaggaa tttcgctatt taaactgatt tgggcgattc ccttagatac ctcgctacat
     3661 acataatcat aatgacttgt attccctcta atgacagctc ccaagcagat aattgcatca
     3721 tattttttac tttttgccat ttttgatgca atcagtggta tttcaaaagc tcctggaacc
     3781 caggctacct ctatatcttt ctcgtttaca ttctctcttt tgagattatc tagtgctcca
     3841 gataataatt ttgaagttat aaattcatta aatctcgcta caacaatacc tattttaata
     3901 ttgtttgcta ctaaattacc ttcataagtg ttcatttatt tttcctccat atttaaaatg
     3961 tgacccattc gatttttctt tgtttctaaa taaaaactat cgtaaggatt ggcttctatt
     4021 tcgattgata ttctactgga aatggtaatt ccatattttt ctaactgttc aaccttgtca
     4081 ggattatttg tcagtaaatg aagtgactga agtcccagat ctttaagcat ttgtgctcca
     4141 atatgatatt ctcttaaatc accttcaaag cctaatgcaa gattggcatc aagcgtatcc
     4201 atgccttgat cttgtaaatg ataggctttt aatttattga taagtccaat tcctcgtccc
     4261 tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa caatcatttt catagcttta
     4321 tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt taaacattcg
     4381 gagtggaccc gacataatac attggcttca tcctctatgt ttcccataat aagagcaaga
     4441 tgatgttccc catttagttt atctatatag ctaattgctt tgaaattacc gtatctagta
     4501 ggcatattga cagttgaaac tcgttctacc agctgatcat atacttttct atattcttgt
     4561 aattctttga tggtaattag tggaatgttg tgtttcttcg agaactgaat taaatcatct
     4621 gttctcatca ttttgccatc atgattcatt atttcacaac ataggccaca ctcttttagt
     4681 ccagctaatt ttaataaatc aacagttgct tctgtgtgtc catttctttc tagaacacca
     4741 cctttttttg caattaaagg aaacatgtgt cctggcctgc gaaaatcaga gggtgttata
     4801 tcttcagcta cacacatacg tgcggtcagt cctctttcct cggcagaaat acctgtggtc
     4861 gtttctttat aatcaattga aactgtaaaa gcagtcttat gattatctgt attgttttca
     4921 accataggtg aaagcattaa ttgattagct aaactttcgc tcataggcat acaaattaat
     4981 cctttggcat aagtagccat aaaattaaca ttttctgttg tagctgcttg tgcagaacaa
     5041 attaagtctc cttcattttc tctatccttg tcgtctataa caagaacaag tcgtcccttc
     5101 tgcaatgctt ctaatgcttc ttgtattttt cgatattcca ttgactgatt atcctttctg
     5161 ctaaaatcca ttttgatata atagttcctt agatatttct gattttggag agttatccat
     5221 cagtttttgc acatatttac ctaagatatc attttcaaga tttactgtac tcccgacttg
     5281 tttactctta agaatggttt gttccaaggt atgagggata acagatactg aaaagtttac
     5341 tttggagact ttagcgacag tcagactaat gccgtcaatt gtaatagatc ctttttcaac
     5401 tattaaatct aaaatttctt tttgtgtgtt gatttgatac catacagcat tatcatcttt
     5461 ttttattgac gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag
     5521 tcgaccgttg acagataagg ctctttctag attcacctca cttccatgtt ttaatagagt
     5581 aagagctgtt cgactccatg tttcattcat tacatcaact gtaaaggatt gatgattgaa
     5641 atgagtaact gtaagacaga taccatttac tgctatacta tcgcctaaat ggatatccgt
     5701 taatattttt gaggctttaa ttgatagttt acaattacga gagtctttct gtattctttc
     5761 aacttttccg atttcttcaa ttattcctgt gaacatggat aaatcacttc actttctatg
     5821 agatagtcat ttcctatttg agaaaatgca taaggtttca atctaatagc gtcatttggc
     5881 aaagaaatgc cttcacctcc gacaggaaac ttggcactgc ctccaaaaat ttttggtgca
     5941 atatatattt tcagctcatc aacaatttgt tgttccaaag cactccaatt cattagactg
     6001 cccccttcta gaactaggct atcaatctgc atgtttccta gatgttgcat taaactcgat
     6061 aagtctatat gattgccttt tttctttatg gaaagtattt cacagccatg attttgatat
     6121 agcttcattt tatttttgtc ttcagaggaa gtggcaatgt aagttttaat atcatttgct
     6181 gtttttacga ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat gatacggata
     6241 ggatttttcc cttcctccaa tctacatgtc agcaaaggat cgtcttgaat aacagtattg
     6301 actcccacca taattgcact aacatggtgt cgtaactgat gcacatgctt tcttgcttct
     6361 tcttcagtaa tccatttgga ttgatttgtt ttagtggcta tttttccatc cattgacatt
     6421 gcatatttca taaaaacata gggtacatgc tgggtaatat actttctaaa actttttatt
     6481 aagttaagac actcattttc taaaattcca acagtaactt gaagattatt ttcctcaagt
     6541 atctttactc cttttccaga tacaatagga ttacagtcta ggcttccaat gactactctt
     6601 gtaataccac tatcgattat agcatctata cagggaggtg ttttcccgaa gtgacaacag
     6661 ggttcaagtg ttacataaag cgtcgctccg acaggggatt ttctacagtt tttaagagca
     6721 tttctctcag catgtgggcc accaaaaaac tcatgataac cttgtccgat aatgtgatta
     6781 tcttttacaa taattgcgcc aaccatagga ttgggattga cgtaaccagc ccctttttgt
     6841 gccagtttta ttgctaattt catatatttt gaatcgctca tctcactacc tccaaaaaaa
     6901 tataccttga ataggggact actcaaggca tacaaaagaa aacttatgcg attaacaaaa
     6961 atgctctgaa atgacaagta atcatttcag agcacgcaaa aagcacaaat atacttttat
     7021 cttctttcat ccagactata ctgtcggctt tggaatttca ccaaatcatg cctttcggct
     7081 cgtgggctat accaccggta gggaattgca ccctgccctg aagatagtta ttcaattaca
     7141 gatgattata gtacttaatt ttgaatatgt caacagataa atacagattg tttttgatat
     7201 actgtatttg tgataatcga ttctcgctcc tcggataaag aaaatatgat atactagata
     7261 aacgaaataa gagagaagga acactatgta cgcatattta aaaggaatca ttaccaaaat
     7321 tactgccaaa tacattgttc ttgaaaccaa tggtattggt tatatcctgc atgtggccaa
     7381 tccttatgcc tattcaggtc aggttaatca ggaggatcag atttatgtgc atcaggttgt
     7441 gcgtgaggac gcccatttgc tttatggatt tcgctcagag gatgagaaaa agctctttct
     7501 tagtctgatt tcggtctctg ggattggtcc tgtatcagct cttgctatta tcgctgctga
     7561 tgacaatgct ggcttggttc aagccattga aaccaagaac atcacctact tgaccaagtt
     7621 ccctaaaatt ggcaagaaaa cagcccagca gatggtgctg gacttggaag gcaaggtagt
     7681 agttgcagga gatgaccttc ctgccaaggt cgcagtacaa gcaagtgctg aaaaccaaga
     7741 attggaagaa gctatggaag ccatgttggc tctgggctac aaggcaacag agctcaagaa
     7801 aatcaagaaa ttctttgaag gaacgacaga tacagctgag aactatatca agtcggccct
     7861 taaaatgttg gtcaaatagg agcagagaat gacaaaacgt tgttcgtggg tcaagatgac
     7921 caacccgctc tacatcgcct atcatgatga ggagtggggt cagcccctcc atgatgacca
     7981 agcattgttt gagttgttgt gtatggaaac ctatcaggca ggcctgtctt gggaaacggt
     8041 actcaacaaa cgccaagctt tccgagaagc ctttcatagc tatcaaattc actcagtcgc
     8101 agagatgact gacactgaat tggaagccat gctggagaat ccagctatca ttcgaaatag
     8161 agccaagatt tttgctacac gcgctaacgc ccaagccttt ctacagttac aggcagagta
     8221 cggctctttt gatgcctatc tttggtcttt tgttgagggg aaaactgtcg ttaacgatgt
     8281 tcctgattat cgccaagccc cagctaaaac acccttatct gagaaattag ccaaagatct
     8341 caaaaaacga ggcttcaagt tcacaggccc agtcgccgta ttgtcttttc tacaggctgc
     8401 agggctagtt gatgaccacg agaatgattg tgagtggaaa ggtcttaaat gatgtctaac
     8461 aaaaataagg gaattctgat ttttgcgatt ctctatacaa tcctctttgt gtttgatggc
     8521 gttaaattgc tggcttcttt aatgccatct gtcattgcaa attatcttgt ttatgtagtt
     8581 ttagctttat atggctcctt cttgttcaag gatagattga tccaacaatg gaaggagatt
     8641 agaaagacta aaagaaaatt cttctttggc gtcttaacag gatggctctt tctcattctg
     8701 atgactgttg tctttgaatt tgtatcagag atgttgaagc agtttgtggg attagatgga
     8761 caaggtctaa atcagtctaa tattcaaagt acctttcaag aacaaccact actgatagct
     8821 gtttttgctt gtgtcattgg acctctggta gaagaattat ttttccgtca ggtcttattg
     8881 cattacttgc aggaacggtt gccaggttta ctaagcatta ttctggtagg acttgttttt
     8941 gctctgactc atatgcacag tttggctcta tcagagtgga ttggtgcagt tggttactta
     9001 ggtggaggcc ttgccttttc tattatttat gtgaaagaaa aagagaatat ctactatccc
     9061 ctacttgttc acatgttaag caacagcctc tccttaatca ttttagctat cagtatagta
     9121 aaatgaaatg agaacaggac aaatcgattt ctaacaatgt tttagaagta gaggtgtact
     9181 attctagttt caatatactg taatatgtga tgaaaatgcc agtaatgata ccgagaaaaa
     9241 agctgagaaa cttttcccag ctttatttgt tatagtcaaa gagaatgact tgttcctgtg
     9301 catctacatg agcatggacc ccaaagggta caattgctct tggagttgcg tggccgacat
     9361 tcagattata gacaatcggg atattgctgt caatgatatc caatagtgcc tctttatagt
     9421 cgtcatggaa agtttcatcc ataggttttc cgaccaagag tccattgatg accgcgaata
     9481 tgccagtgtc ctttaaagtt agcaacattt ttttgaagtc ttctggctta ggcttttctt
     9541 cgcttgtttc gagcaagagg attttccctt cccagtctga caagtcaggg aaaagtttgt
     9601 atttttggca gagttccgtg ctatctgcgt atcgagagtt gtcaaagata tcgtagaggg
     9661 attcgaggca accaccgagg attttcccct cgaactgagc acttccttgc aacaagtcaa
     9721 aacctgtatt tgtatgactg acacgaggtg ttcccagggc cgtgggacta aaatcagttc
     9781 gttcctcata ccaaacgtca ctagggcgga tttctgaaat tcttcccgtc ttaatcaatt
     9841 ctttaaagta gtgaaggcta taggctagca tttctttgtc taattcacaa atgtctgcta
     9901 aaaaggattg accataaaaa gtcttgattc ctaatttatg caacatgagg tggttcatgg
     9961 ttgtatccga gaagccaaga aaaatttttt gcttgataac cttttggagt tggtcatttt
    10021 caaaaagata aggtagcaag cgataggtat cgtctccacc gatggcacat aggatcatgt
    10081 cgatgctatc atcagaaaag gcatgaatca aatcctctgc acgagcttca ggatggtcct
    10141 tgataaagtc taatcctttt aacgaatggg acaaaaagat gggattgagt cccagatcct
    10201 tgagacgttg gatacccaag tccacttcgt gtttgacaaa atcctctccg ataatgccac
    10261 tagataaact aacaatacca atagtagaaa ccatatctca tcctcctaga aatagattga
    10321 gcctatttta tcacaaaata taagagaaag ctatgtggga tttcagaaga atacttttaa
    10381 tactcttcga aaatctcttc aaaccacgtc agttttatct gcaacctcaa agctgtgctt
    10441 tgagcaacct gcagctagct tcctagtttg ctctttgatt ttcattgaat ataactcaaa
    10501 aaagtaagtg aaaaagcaac cgcacctgca gttgctttta tcgttttctt attcttgata
    10561 gcgtgttggt cctgcacttg cactacggat attcaagcgt ttcttgagat agaagcgaag
    10621 ggctaggagg gctgctccaa taatagctag tggcaatgga tccagtactg ggttaaggct
    10681 agctggtagg aagcttgttg caaagaagac aagcaaccaa aggaacatag aagctaggat
    10741 aactagtaca gatttccaga aaggtggacg ttgactgcga tccatatctg atccatagta
    10801 ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca ccaaccagtc caactaatag
    10861 aagagtaatc aatccatagc cgaaagcttg gtctgccgca aagaaggttg tgagggcgct
    10921 gacaagggca aagaggctag tgatgaaaag agctgagtcc ataatcatca gttttgggtc
    10981 atcattttct tttggatgct ctttttcgta ctgctctttg acagtgaagc tatgagccca
    11041 atgagttggt gcgccgtata gggaacgggc agttgtacct ttagattgct cctcaaggat
    11101 ttggggaatg acttcctcaa aaatagtctg gatttcagcg tctgttttcc catctttgat
    11161 gaattgttgg gtagcaatgt ggacaaactc ttggtttttc ttagttaatt tttgtagatc
    11221 aatttgagac ataggaactc ctcttagaac cattttttat ggatgagata gagagtgagc
    11281 gagacactca tagcaaaggc gataaagacg attaaccaga aggcatttgg ctctccgttt
    11341 agggggattt cattatcctt aaagttcatc ccgtaggcag aaaagaccat ggttgggatg
    11401 gacatgacga tggtcacaag ggccaaggtt ttcatgatgt tgttctggtt gttagaaatg
    11461 atagaggcaa aggtctctgt catagaatgc aagacgtttc cataaatatc tgccatctcg
    11521 atggcctgtt gggtttcaat cagggtgtct tcaagcaggt cttcgtcctc aaggtatttc
    11581 ttgatattgc tggttgaact ggtcaatttc ttaatcacgc gctcatttgt tttgagggag
    11641 gccttgaaat agacgatagt tttttccaat tccatgagct caatcaattc ttcattacga
    11701 gttgattgat gcagttgact ttcgatttgt tcactcttgc ggtcgattga acgaagggct
    11761 gttaggtaaa gctctgcatt gcgataaaga atttgaaaga taaaacgtga acgcatgaag
    11821 gtatagaaat tacgcaatcg acggttgata aagacatcaa ggacaggtag tggttccaaa
    11881 cacgtagtga taatggtttc ctcagtgatg ataataccaa gcgggatggt tacgtagtag
    11941 gtgcggttat ttctttcctc cgtgaccggc acgtctacga taatcagggt atactcgtct
    12001 tcaatggtaa tacgagacat ttcttccgca tcgagcggtg ctcgaaggtc ggcaatatca
    12061 atatcgaagg tgttggcgat ttcgagtgat tcattttgag tcggattgac gagattgatc
    12121 caagtacccg gttcaagcgt atcgatctct ttaaattcag ttgttgtaga gagaaaaact
    12181 tgtttcatat cccttatcct ttctcatttt tcagattttt tcacactgta ctattatact
    12241 acaaaatcgg ccttttgggt aatagaatct cacttttttt ggtataatgg taagcaataa
    12301 tggactagaa agaacaaaga tgcaagataa aattgtcatt catggggcgc gtgcccataa
    12361 tttaaaaaat attgatgtgg agattccgcg agacaagttg gttgtcgtga ctggcttgtc
    12421 aggttcaggg aagtccagtc tggcttttga tactctctat gcggagggac aacgtcgcta
    12481 tgtagagagt ttgtccgcct acgctcgtca gttcttggga aatatggaaa aaccagatgt
    12541 agatgccatt gatggtctca gcccagctat ttccatcgac cagaaaacga ctagtaaaaa
    12601 tcctcgctcg acggtgggaa cgacgactga aatcaatgac tatctgcgtc tcctctacgc
    12661 acgtgtgggg acgccttact gtatcaacgg acatggagct atcaatgctt cttctgtgga
    12721 gcaaatcgtt gataaggttt tggagttacc tgaacgccag cgcttgcaga tcttggctcc
    12781 tgtcatccgc aagaaaaaag gccaacataa gagtgttatc gagaaggttc agaaagacgg
    12841 gtatgttcgt gtccgtgtgg atggggaagt ctatgatgtg accgaagtgc cagagttgtc
    12901 taagagcaag caacacaata tcgatgtcgt ggttgaccgt attgttatca aggagggcat
    12961 tcgtagtcgt ctctttgatt ccattgaggc tgcccttcgt attgcagaag gttatgtcat
    13021 tatcgacacc atggacgact cggagttgct cttctctgag cattatgcct gtccagtttg
    13081 tggatttact gtcccagagt tagaacctcg tctcttctct ttcaatgctc cctttggctc
    13141 ttgtagtgag tgtgacggct tggggattaa gctggaggtg gatactgatt tggtagtgcc
    13201 agatgccagc aaaaccttac atgagggagc gctggcacct tggaatccta tctcatccaa
    13261 ctactatcca aacatgttag agcaggccat gaaagtcttt ggagtggcta tggataagcc
    13321 ttttgaggac ctgtcagaag aagataagaa cttgattctc tacggctcag atggtaagga
    13381 attccatttc cattatgaaa atgaatttgg tggtgtgcgc gatatcgaca ttccgtttga
    13441 gggagttatc aataatatca aacgtcgtta ccatgaaacc aatagcgatt acactcgcac
    13501 tcagatgcgt ctctacatga atgagctgac ctgcggaacc tgtcaaggct atcgtctcaa
    13561 tgaccaggcc ttgtctgtcc gtgtgggcgg ccagcaaggg ccacatattg gagaaatctc
    13621 agacctgtct atcgctgacc acttggactt ggtgagccag ttaactttgt ctgaaaatga
    13681 agccatcatt gctcgtccca ttctcaagga aatcaaggat cgtttgacct tccttaataa
    13741 tgtgggtctt aactatctaa ccctgtcacg ttcagcagga accctttcag gtggggaaag
    13801 tcagcgcatt cgtttggcaa cccagattgg ttccaaccta tcaggtgtcc tctatatcct
    13861 agacgagccg tcaatcggtc ttcaccagag ggacaatgac cgcctgattg ccagtctgaa
    13921 aaagatgcgt gacttgggca atactcttat cgtggtggaa cacgacgaag ataccatgcg
    13981 tgaagctgat tatctgattg acgttggtcc tggtgccggt gtttttggtg gtgagattgt
    14041 tgcagcaggt acacctaagc aagtggctcg caacagcaag tctatcacag gtcagtactt
    14101 gtcaggcaaa cgtgtcatcc cagtaccaga agagcgccgt gtcggaaatg gtcgttttat
    14161 tgaagtgaca ggagcgcgtg agaacaactt gcaaaatgtc acggctcgct ttccactagg
    14221 aaaatttatc gcagtgacag gtgtgtcggg ttcagggaaa tcgactctaa tcaacagcat
    14281 tctcaaaaaa gccattgccc agaagctcaa ccgtaattca gacaaacctg gtaagtttaa
    14341 gactattaca gggattgagc atgtcgaccg tttgattgat attaaccaga gccctatcgg
    14401 acggacgccg aggtctaacc cagctaccta tacaggagtt tttgacgata tacgtgacct
    14461 ttttgctcag acaaatgaag ccaagattcg aggctacaag aaggggcgct tcagtttcaa
    14521 cgtcaaggga ggtcgctgtg aagcttgctc aggtgacggg attatcaaga ttgagatgca
    14581 cttcttgcca gatgtttatg tggcttgtga agtttgccac ggaacccgct ataacagtga
    14641 aaccctagaa gttcactaca aggaaaagaa tatttcgcag gtcttggata tgacggtcaa
    14701 cgatgcggta gaatttttcc aacacattcc gaaaattcaa cgcaaactcc agaccatcaa
    14761 ggatgtaggt ctaggctatg tgaccttggg acagccagct accacccttt ctgggggaga
    14821 agcccaacgt atgaagttag ctagcgaact ccacaaacgc tcgacaggaa aatctttcta
    14881 cattctggat gagccgacga cagggcttca tacagaggac attgctcgcc tgctcaaggt
    14941 tttagctcgc tttgtagacg ccggcaatac agtcctcgtc atcgagcaca atctggatgt
    15001 tatcaagacg gcagaccata tcattgactt gggacctgag ggcggtgtcg gtggtggaac
    15061 catcatcgta acaggaactc cagaagaagt agctgccaac gaagccagct atacaggaca
    15121 ctatttgaaa ggaaagttac atcatgaata aacgcgtaca agcatttcta gctaaaatgc
    15181 aagaaaaaga actagatggt atcatcatca acaatcttaa aaacgtctat tatttgactg
    15241 gtttttgggg ctcaaacgga acagtcttta tcagccgtga ccgtcaggtc ttagtgacag
    15301 actctcgcta tatcatcgca gctaagcaag aaaccagtgg ttttgagatt gtggctgatc
    15361 gtgatgaatt ggctgtcatt gcaggaattg ttaaggacat gaacttgact cgtatcggtt
    15421 ttgaagatga gatttcagtg tcttattacc accgtatgca ggcagctttt gcaggtttga
    15481 acttgcttcc acaaactcag tttgtggaag gtcttcgtat gattaaggat gaggcagaga
    15541 ttgcagcgat tcgcaaggct tgttctatct cagaccaagc tttccgcgat gcgcttgact
    15601 ttatcaaacc aggaaaaact gaaattgaga ttgccaactt ccttgatttc cgcatgcgtg
    15661 agttgggagc atctggctta tcttttgata cgatcctagc tagcggtatc aattcttcta
    15721 aaccccatgc ccatccaatg cacaaaccag tggagttggg agaagccatc accatggact
    15781 tcggctgtct ctatgaccac tatgtcagtg atatgacccg gactatctat ctagggcatg
    15841 ttagcgatga gcaggcagag atttacaata cggttctaaa agctaaccaa gccttgattg
    15901 accaagctaa ggcaggctta ggtttccgtg actttgacaa aatccctcgt gatattatca
    15961 ttgaggcagg ttatggtgac tactttactc acggcattgg ccacggtatt ggtctggata
    16021 tccatgagga accctacttt agtcagactt ctacagaaac tattaagaca ggtatggcct
    16081 tgatcgatga accaggtatc tatatcgaag gcaaatatgg cgttcgtatc gaggatgata
    16141 tcctgattac agagacaggt tgtgaattat tgaccctagc tccaaaagag ttgatagtca
    16201 tttagttgtt tgtcaagaaa aaagtacgaa aatgacgaaa aaagtcaaaa aaaattaaaa
    16261 ataggtcgca agtcggatgt tttttatggt ataatagact aaactgatag taacatgtag
    16321 cgaaaggggt aggtacatga ttaaaattta tacagtctca agttgtacta gctgtaaaaa
    16381 agcaaaaacc tggctcaatg cccaccagtt aagttataaa gaacaaaacc ttggtaaaga
    16441 aggaattacg agagaagaat tactggatat tctaaccaaa acagataacg gaatagccag
    16501 catcgtttcg tctaaaaatc gctatgccaa agcccttgga gtggatattg aagatttgag
    16561 tgtcaatgaa gttctcaatc tgattatgga aacaccgaga attttaaaga gcccaatcct
    16621 tgtagatgaa aaacgcctgc aagttggcta caaggaagac gatattcgtg ccttcctacc
    16681 acgatctgtc cgtaatgtag aaaatgcaga agcacgtttg cgtgcagctc tataaacatc
    16741 aaggctggga gcacttccca gtcttattct attttaattt caaaaagaaa gaagaaagaa
    16801 atgaaaaaaa tagttcttgt tagtctagct ttcctttttg tcctggttgg ttgcggacag
    16861 aaaaaagaaa ctggaccagc tacaaaaaca gaaaaagata cgcttcagtc ggcattgcca
    16921 gttattgaaa atgctgagaa gaatacagtt gtaactaaga ctttggtctt gcccaagtca
    16981 gatgatggta gccagcagac acaaacaatt acttacaaag acaagacttt tttgagtcta
    17041 gctatccaac aaaaacgtcc agtctctgat gagttgaaga cttatattga ccaacatgga
    17101 gtggaggaaa ctcaaaaagc tcttcttgaa gcggaggaga aggataagtc tatcattgaa
    17161 gctcgtaaat tggcaggttt caaacttgaa acaaaactat tgagcgcaac ggaacttcaa
    17221 acaacgacta gttttgattt tcaagttctg gatgtcaaga aggcttccca gttggaacat
    17281 ctgaagaata ttggtttgga aaatcttttg aaaaatgaac caagcaaata tatttcagat
    17341 agattggcaa atggcgcgac agaacaatag aaaatccaaa taaatagact gcctgaattg
    17401 tagaaggtaa ggaattatgc tataatggta ctattctaag gaaagagggt gttagaatgg
    17461 gatttactga agaaacagta cgttttaaat tggacgattc caataaaaaa gaaattagcg
    17521 aaactttgac agatgtttat gcttcgttga acgataaggg ttacaaccca attaaccaaa
    17581 tcgtaggtta cgtattgagt ggagaccctg cctacgttcc tcgttataat aatgcacgaa
    17641 atcaaatccg taagtatgag cgtgatgaaa tcgttgagga attggttcgc tactacctca
    17701 aaggacaagg agtcgatcta taacctatga gaattatggg attggacgtc ggttcaaaaa
    17761 cggtaggggt ggcgattagc gatccgcttg gttttacagc tcaagggctt gaaatcatcc
    17821 agataaatga agaacaaggc caatttggtt ttgaccgcgt taaggaattg gttgatactt
    17881 acaaggtgga acgatttgta gtgggcttgc ctaaaaacat gaacaataca agtggaccgc
    17941 gcgtagaagc tagtcaagcc tacggagcaa agctagaaga gttttttggt ttaccagtag
    18001 actatcagga tgaacgcttg acaacagtgg ctgctgagcg catgttgatt gaacaagcag
    18061 atatcagtcg caataagcgc aagaaagtca ttgataagtt agcagctcag ctgattttac
    18121 aaaattattt agatagaaaa ttttaatata aaggagaggc tatgtcacac gatcataacc
    18181 acgaccacga agaacgtgaa ctaatcacac tagtagatga gcaaggaaat gaaaccttgt
    18241 ttgaaatcct tttgacaatt gatggaaaag aagaatttgg taaaaactat gttcttctag
    18301 taccagttaa cgcagaagaa gacgaagacg gacaagttga aatccaagct tactcattca
    18361 ttgaaaatga agatggaaca gaaggcgaat tgcaaccaat cccagaagac tcagaagacg
    18421 aatggaacat gattgaagaa gtcttcaaca gctttatgga ggagtaaaaa cgtccggggg
    18481 acgtttttag ccctgcgcta gaaattagaa acgcaggtag tctgggagac tgtatcagcc
    18541 caactccaga aatggggaag agttggaacg tccagtgaac atttttaccc caactcttag
    18601 aaattgagaa gagttggaac atctagtgga tgtttttagc ccatattcac attcatagta
    18661 gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt gtttttatta
    18721 gtaaccatac tttaatgcga taattgattg gacttttgtc aaggagatgt gtatgtttga
    18781 agtagaagaa tggctccata gtcggattgg tttgaatttt cgatcaggtt tgggccgaat
    18841 gcagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta tccacgtaac
    18901 agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta tggggcatgg
    18961 caaaaaagtt gcgaccttta cctcccctca tatcgtatcc atcaatgacc gaatctgcat
    19021 taatgggcaa cctatagcag acgcagactt tatccgtttg gctgatcagg taaaggagat
    19081 ggagaaaacg cttctgcaaa ctcctgacca gttgtccttt tttgaattgc tgaccttggt
    19141 tgcttttctt tattttaggg agcaggaggt ggatttggtt ttattagaag tgggaattgg
    19201 tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca cctccattgg
    19261 gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc agaaagctgg
    19321 tattttcaag gctggtaaaa aggcagtgat tgcgaaattg cctccagaag ctagacttgt
    19381 ctgtcagaaa aaagccgaat ctttagctgt tgacctttat caggcaggtc aagatttttc
    19441 agtgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga acataggctt
    19501 agaaggagcc tatcagcagg agaatgcggc cttggcgttg caaacttttc ttctttttat
    19561 gggagaaaga aaggaagcta ttgatgaaca ggctgtaaga aaggccttgg aacagaccca
    19621 ttgggctggt cgcttggagc gtattcgccc acagatttac ttggatggtg ctcataacct
    19681 ccctgccttg actcgcttgg ttgagtttat caaagaaaaa gagcaggaag gctatcgacc
    19741 tcaaatcctc tttggatcct tgaaacgtaa ggattatcaa gggatgttgg gttatctgac
    19801 tgaaaattta cctcaagtgg aactcaaaat gaccggcttt gactatcaag ggtctttgga
    19861 cgagacagat gtaacaggtt accatgtaat tccctcttac cgagaattta tcagcagttt
    19921 cgaagaaagg gcagacgctc aagacttgct gttcgttaca gggtctctct attttatctc
    19981 agaagtacgg ggctacctgc tggaccgtga gcagataaat tgaccccctt ttttgaactt
    20041 gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc agaaaggaaa
    20101 ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag ttttagtctc
    20161 ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgttgctca gcaggtccaa
    20221 cagcctgctc aacagaatac caatactgca aatgcaggag gtaaccaaaa tcaagcggct
    20281 ccagtacaaa accaacctgt tgctcaaccg accgatattg atgggactta tactggtcag
    20341 gatgacggag accgtatcac tttagtggta actggaacga ctggtacatg gactgagctc
    20401 gaatctgacg gggatcagaa agtcaaacag gttacatttg attcagcaaa tcaacgcatg
    20461 attattggcg atgatgtcaa aatttacact gtaaacggta atcaaatcgt cgtagatgat
    20521 atggatagag acccatcgga ccaaatcgtt ttaactaaat aagactatgc aagtagaaag
    20581 ggctggattt ttcagccttt ttacttttac ctagaaaata atcataaata cttgccttct
    20641 accgaatacc tgcgttatac tagtatcaat tacttgtttt tagcattcaa actatcaagg
    20701 aggggatatg aaatatagga aatttcaatt attgatgtcc aagtatggct ttagtctttc
    20761 gattatgcta cttgaacttt gtcttgtttt tggtctcttt ctttatttag gacgcatggc
    20821 tcccatttta tggattactg tcctcattct actgagtatc atcacaatca tttcgatagt
    20881 caaccgtaat acgactcctg agaataaggt aacctggttg ttagtagcct ttgtgccagt
    20941 atttggtccc ttgctctatc tgatgtttgg tgaaaggcga ttgtccaaaa aagaaatcaa
    21001 acaactgaag aagctaggct ctatgcattt ccaagaagca aatagccagc tactaaaaga
    21061 gaaattaaaa gaaagtgaca aggcagctta tggagtcatc aagtccttat tgagtatgga
    21121 taccaatgct gacatctatg atcaaactgc ctctacattt tttcctaacg gagaagctat
    21181 gtggaaaaag atggtagaag atcttaaaaa ggctgagaaa tttattttct tggaatatta
    21241 cattatagaa gaaggtttga tgtggaatcg catactagat atactagagc aaaaggtagc
    21301 tcagggtgta gaggttaaga tgctctatga tgatatcggc tgtatggcta ctttaacagg
    21361 agattatgca catcgacttc gtcagctggg catcgaggcc cataaattca ataaagttat
    21421 tcctcgtttg acagtggctt ataataacag agatcataga aaaatattga ttgttgatgg
    21481 tcagatagcc tatactggtg gggtcaatct ggcagatgag tacattaacc acgtcgagag
    21541 atttggttat tggaaggata gtggaattcg cttagacgga ctagcagtaa aagccctgac
    21601 acgcttattt ttgaccactt ggtacattaa tcgaggagaa attagtgatt ttgatcaata
    21661 tcatttagaa aatcattcta tcccgagtga cggtttaacc attccatacg gaagtggacc
    21721 caagccaatt tttcgagcgc aggtagggaa aaaagtttat cagagtttaa tcaatcaagc
    21781 aacagaatcg gtctatatta cgacacctta tttgattata gattatgatt taacagagac
    21841 aatcaaaaat gcagctatga gaggggtcga tgttcgaatt atcacccctt acataccaga
    21901 taagaagttc attcagttag tcacgagagg agcttatccc gaccttcttt ctgctggtgt
    21961 tcggatttat gagtatagtc caggttttat tcatagtaag cagatgttgg tagacgaaga
    22021 ttttgcggtg gtggggacaa tcaatctcga ctaccggagc ttggtacacc attatgaaaa
    22081 tgcagtctta ctctataaaa ctccttctat aagggaaatc gcccgagatt ttcgaaatat
    22141 atttgcagat tctcaggaag tctatcctca ttctatcaaa acgagctggt atcaaaagct
    22201 tgtaaaagaa atcgcccagc tattcgcccc tatcttataa gaaatctaga acttaggata
    22261 caaaccagcc ctatttttct tgtcttttac taatagaaag aaagaggagg ggaattcatg
    22321 ctaactaagg aagaagtgaa tgatatgatt gagttcaaac agacacattt acaccgcttt
    22381 cgggaaattg aaacctttgt gaaactatgc aaaaaatcac tcaaacagcc atcgcaagct
    22441 gacaatccta ggactttttg atatactaag acagataaat tgaacaggag aaacgatatg
    22501 agtgtgtatg gtagagtaga agaagttcat aaggagaatc gtgaacctct agaataccaa
    22561 atcgaacaag aatcgcatca tcgtgaatca agtcgtcttc ctttggtgaa aattttacta
    22621 tggagtacgc ttgtaacggg gataactcta ggagtaccgc tattactcga cttaatgagt
    22681 gcacaagaag tgcaggattt ttatgcaggt tgggcgcttc atcagacagg gaagatttac
    22741 agcgactatt atggaagtca aggtttgctt tattatttgc tgacttacgt gagtcagggc
    22801 ggatttttct ttgccatctt tgagtggtta gccttggtag caggaggatt tttccttttt
    22861 agatcagcgg acaccttgac agagcaagga gaccaagctg gacatctggt gactattttt
    22921 tacatgctag ttacaggtct tgcttttggt ggaggctatg cgactctttt agcgcttcct
    22981 ttcttattcg cagcctttag tttagttgcg gcttacctaa gcaatccaag ccatgataag
    23041 ggatttgtac ggattgggct agctttggca ggcggatttt tctttgctcc cttatcatcg
    23101 ctcctgttta ttgctgtagt gggtttaggc ttgttggtct ttaaccttgg gcatagacgc
    23161 tttgcgcatg ggttttatca gtttcttgca gtggctttag gtttttcact tgtcttttat
    23221 ccaactgcct actatagtgc tgcaacagga agttttgggg aagcgattag tggtattcgt
    23281 tatcctattg acagtattcg ctttgatttt acttctaaaa ttttagagaa tatgtttttt
    23341 tatggcttgt tgtcccttgg tttgggattt gtggtttgta tctttttagg tctctttcaa
    23401 tccaaaccct ttaaactata cgtcatttcg gttcctgcaa gtcttgttgt aattttaggt
    23461 ttgattttac ttttcttttc acaagagcct ctgcacgctt cttatttgat ggtcgtcttc
    23521 cctgttttcc tacttttatt ggtaaccaat attaagagtc aacagagggg gcgtagtgct
    23581 agaagaagcc gaagagaaac gccagttagc ctatggagtc gtttcttcaa aggaaatcta
    23641 tatctgctag tttttgggtt tgtctatctt ttgtctgttc cttttttgat gaagtttgtc
    23701 ctttatccag taccttatca agaacgtaat cgtcttgctg atttggtaaa agaggagaca
    23761 aatacggaag atgctatcta tgcatgggat gatactgcga ctctttatcg taagagtgag
    23821 cgcttgtcgc catcggcgat tttgtccccg ttgcactata cagcaactga ggaaaatcgt
    23881 aataagttac ttaatgactt gaaagaaaaa caacctaagg tgattgtggt aaatgacaag
    23941 gtggtagtct ggtctgaagt ggaaacactt ttaaaagaaa attaccaaca agtaaagact
    24001 gattactcag agtttaaagt ctataaaatt aaataaccaa atcaatatct tgtgtatttt
    24061 tagaaatttt aggattttta acacaagata ttgatttttc tttttagagt ggtataatac
    24121 tttttagaaa gaacatttta gaaaagagca tgcgtatgat tgcactagaa gaaaaaatta
    24181 caattttgcc aactctcttc gtcgagaaac gagatgggag acgtgttgta tttgatgtgg
    24241 acaagattga caaggctctc cacaaggcgg ctgacaaggt tatggatgtg acacccctgg
    24301 ttgaaaaacg cctcaatgat ctgactgagc gaattattac agaaattcat agtcgctttc
    24361 cacagggaat taagatttac gaaattcaaa atatcgtaga acatgaactc cttgaagcca
    24421 aagaatatgc gctggctgag gagtatatta cttatcggac acagagggat tttgagcgct
    24481 caaaagcgac ggatatcaac tttagtattc ataaacttct caacaaagac cagacagttg
    24541 tcaatgaaaa tgctaataaa gacagtgatg tctttaacac tcagcgtgat ttgacagcag
    24601 ggattgttgg gaaatcaatc ggactgcaaa tgcttcctaa gcacgtagcc aatgcccacc
    24661 aaaaggggga tatccactat cacgatttgg actacagtcc ctatacccct atgaccaact
    24721 gctgtttgat tgattttaag ggtatgttgg aaaatggttt taagattgga aatgcagagg
    24781 tagagagtcc caagtctatc cagactgcga cagcacagat ttctcaaatc attgccaacg
    24841 ttgcttctag ccagtacggt ggctgttcag ctgaccgtat cgatgaaatt ttggcgcctt
    24901 atgcagagaa gaactatcaa aaacatctca aagatgcaga agagtgggta ttgcctgaaa
    24961 aacgggaaga ttacgcttgg aagaaaacgc aaaaggacat ctacgatgcc atgcaatctc
    25021 ttgagtatga aatcaatact ctcttcactt caaatggaca aacacctttt acttcgttag
    25081 gttttggtct gggaaccagt cgttttgaac gagaaattca aaaagctatt ttaaacattc
    25141 gcatcaaggg tcttggttca gaacaccgta cggctatctt tcctaaactt attttcactc
    25201 tgaaaagagg ccttaattta gaggaaggaa ctcccaacta cgacatcaag cagttggctc
    25261 ttgagtgtgc aaccaaacgg atgtatccag atgttttatc ttacgataag attgttgact
    25321 tgacaggatc cttcaaggtg cctatgggtt gccgttcttt cctccaagga tggaaggatg
    25381 aaaatggtgt agaagtcaat tcaggtcgca tgaatctggg tgttgtgacg gttaatctgc
    25441 ctcgtattgc tcttgagtct gaaggtgata tgaataagtt ctgggaaatc ttcaacgagc
    25501 gcatgaatat cgcagaagat gctcttgttt accgtgtcga acgcactaaa gaggcgacac
    25561 cagcgaatgc tcctatcctt tatcagtacg gtgcttttgg ccatcatcta ggtaaagaag
    25621 aaagtgttga ccagctcttt aagaatcgtc gtgcgaccgt ttcgctgggc tatatcggct
    25681 tgtatgaagt agcgacagtt ttctttggta acagctggga aagtaatcca gatgctaagg
    25741 aattcacgct agacatcatt cacgatatga aacgccgtgt agaagagtgg tcagaccaat
    25801 atggctacca tttctctatc tactcaacac catccgaaag tctgacagac cgtttctgcc
    25861 gactagatat agacaagttt ggctctattc ctgatatcac agacaaggaa tactacacca
    25921 actctttcca ctacgatgtt cgtaaaaatc caacaccgtt tgaaaaattg gactttgaga
    25981 aagtctatcc agaagcaggt gcgtcaggtg gtttcatcca ttattgtgag tatccagtcc
    26041 ttcagcaaaa tccaaaggcc ttggaagctg tctgggatta tgcttatgac cgtgtaggct
    26101 atctaggcac caatactccg attgaccgtt gctacaagtg tgactttgaa ggggattttg
    26161 aaccaactga gagagggttt gcttgtccaa actgtggcaa tagcgaccct aaaacagtag
    26221 atgtggtgaa gcgaacttgt ggctacctag gtaatcctca agcaagaccg atggtcaacg
    26281 ggcgtcacaa ggaaatcgct gcgcgtgtca aacatatgaa tggttcaacg attaaaatag
    26341 ctgggcatca agtaacaaat tagaaagaaa tgaaatggga aaatatcaac tagacgataa
    26401 ggggcgcgca caagtgaccc gttatcacga gaaacactct aaaggtggag ctggtaagaa
    26461 agaacgcttg cttagcttca gagaacaatt tttaaacaag aacaagaaaa aataaaagtg
    26521 agagccagct ctcgcttttc tcatagtggg aggtaaggat ggaattacgc agaccaagat
    26581 tagcggataa gaaagctgtt ttagatatga tgacagagtt tgaaaaattt cagtcgcctc
    26641 acgacggcgg tttctgggat acagagaact ttgtgtatga agactggtta gaaagcaatc
    26701 aggaacagga aatgggaatt aatctgcctg aaggatgggt tcctgcaatt cagttagtgg
    26761 ctttttctga gaaaggtcaa gcagttggat ttcttaatct ccggttgcgc ctcagtaact
    26821 ttctactaga agaaggtggg cacattggct actccatccg tccatctgaa agaggcaagg
    26881 gttatgcaaa agagactctc cgtcagggct tgcaagttgc taaggaaaag aacatcaaga
    26941 aagctctggt gacctgtagc gtgaataatc ctgctagcag agcagtcatt ctagcaaatg
    27001 gtggaatatt tgaggatgct cgcaatggag tcgagcgtta ttggatagag gtagcgaatg
    27061 aataatccaa aaccacaaga atggaaaagc gaggaactta gtcaaggtcg tatcattgac
    27121 tacaaggcct ttaactttgt tgatggcgaa ggcgtgcgta actctctcta tgtagcaggc
    27181 tgtatgtttc actgcgaggg atgttataat gttgcgactt ggtcttttaa tgctggcatt
    27241 ccctatacag cagaattaga agagcagatc atggcagatc ttggtcagcc ctatgttcaa
    27301 ggtttgactt tgttgggagg ggagcctttt ctcaatactg gcattctctt gccacttgtt
    27361 aagcggattc ggaaagaatt gtcagacaag gacatctggt cctggaccgg ctacacttgg
    27421 gaagaaatga tgttggaaac tccagataaa ctggaactct tgtcactgat tgatattctt
    27481 gtcgatggaa gatatgatcg aactaagaga aatcttatgc tccagtttcg aggttcgtct
    27541 aaccaacgaa ttatcgatgt gcaaaaatcg ctcaaaagtg ggcaagtagt gatttgggac
    27601 aagctcaatg acggaaaaga aagctatgaa caggtgaaga gagaatgaag aaaaaaggct
    27661 tagtagacca actagtctca gagatcgaga cggggaaagt caggacactg ggaatatacg
    27721 gtcatggagc ttcaggtaaa tcaacctttg cacaggaatt gtcccaagct ttagattcta
    27781 ctacagtaaa tttgctagaa acagatccct atatcacctc cggacgctat ttggtagtac
    27841 ccaaggacgc gccgaatcaa aaggtgacag ccagtctgcc agtggcgtat gaactggaga
    27901 gtttgcagag agatatcttt gccttgcagg cgggtatgga tgtcttgaca attgaagaac
    27961 cttggaaggc tagtgaagtc ttgtctggag ccaaaccaat tttgattgtc gaagggatgt
    28021 ctgttggttt tctacccaag gaactctttg aaaaaaccat ctgtttctac acggatgagg
    28081 agaccgaatt aaagcgacgc cttgctagag atacgactgt gagaaatcgc gatgcatcct
    28141 ttatattggc tagccatcag atgagacggg agcagtatct gcgatactat aaagaaactg
    28201 agtctaaggc ggatatctta gtggaccaat cagaagataa atttgatgtc aagaggactt
    28261 aacttatgta tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa acagtttcat
    28321 ctcaaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg caggggattt gtgttattct
    28381 attatggtgc tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt
    28441 gcattgccac gcaacgccgc gtcggttttc ttgtggagct agcctattat cttaaataga
    28501 cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca
    28561 ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca
    28621 agttgcgggt ccaatcccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac
    28681 tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga
    28741 tatcgttaac ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg
    28801 tgtaaacgta gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa
    28861 tctaattgaa cacgggctaa actcggtgtg aaaaagataa acttcctcgc gtctgctaga
    28921 cactgcgtta gtttcctatt ttcactttga gtttgacgcc ctttgtatct tagacttgag
    28981 cataaaaaac gctcgttaaa aactttttga ataaaaaata tagaaaagga actattttct
    29041 catgacaaaa ggaatcttag ggaaaaaagt gggaatgact caaatcttca ctgaagctgg
    29101 cgaattgatc cctgtaacag ttattgaagc aactccaaac gttgttcttc aagttaaaac
    29161 tgttgaaaca gacggataca acgctatcca agttggtttc gatgacaaac gcgaagtatt
    29221 gagcaacaaa cctgctaaag gacatgtagc gaaagctaac acggctccta agcgcttcat
    29281 tcgtgaattc aaaaacgttg aaggcttgga agttggtgct gaaattacag ttgaaacatt
    29341 cgcagctgga gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt tccaaggtgt
    29401 tatcaaacgc cacggacaat cacgtggacc aatggctcac ggttctcgtt accaccgtcg
    29461 tccaggttct atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg
    29521 gcgtatgggt ggcgaccgcg taacaattca aaaccttgaa gttgtacaag ttgttccaga
    29581 aaagaacgtt atccttatca aaggtaacgt accaggtgct aagaaatctc ttatcactat
    29641 caaatcagca gttaaagctg gtaaataata aagaaagggg aaatcagtca caatggcaaa
    29701 cgtaacatta tttgaccaaa ctggtaaaga agctggccaa gttgttctta gcgatgcagt
    29761 atttggtatc gaaccaaatg aatcagttgt gtttgatgta atcatcagcc aacgcgcaag
    29821 ccttcgtcaa ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa
    29881 accatggcgt caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct caccacaatg
    29941 gcgtggtggt ggtgttgtct tcggaccaac tccacgttca tacggctaca aacttccaca
    30001 aaaagttcgt cgcctagctc ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt
    30061 cgtagctgta gacgctcttt catttacagc tccaaaaact gctgaatttg caaaagttct
    30121 tgcagcattg agcatcgatt ctaaagttct tgttatcctt gaagaaggaa atgaattcgc
    30181 agctctttca gctcgtaacc ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt
    30241 tcttgacatc gcaaatagcg acaaacttct tgtcacacaa gcagctatct ctaaaatcga
    30301 ggaggttctt gcataatgaa tttgtatgat gttatcaaaa aacctgtcat cactgaaagc
    30361 tcaatggctc aacttgaagc aggaaaatat gtatttgaag ttgacactcg tgcacacaaa
    30421 cttttgatca agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac
    30481 acaatcaacg taaaaccaaa agctaaacgt gttggacgtt acactggttt tactaacaaa
    30541 actaaaaaag ctatcatcac acttacagct gattctaaag caatcgagtt gtttgctgct
    30601 gaagctgaat aatctaagga ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa
    30661 acggtcgccg taatatgact tctttggatt tcgctgaaat cacaacaagc actcctgaaa
    30721 aatcattgct tgttgcattg aagagcaagg ctggtcgtaa caacaacggt cgtatcacag
    30781 ttcgtcacca aggtggtgga cacaaacgtt tctaccgttt ggttgacttc aaacgtaata
    30841 aagacaacgt tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca
    30901 tcgctcttgt acactacact gacggtgtga aagcatacat catcgctcca aaaggtcttg
    30961 aagtaggtca acgtatcgtt tcaggtccag aagcagatat caaagtcgga aacgctcttc
    31021 cacttgctaa catcccagtt ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg
    31081 gtggtgaatt ggtacgtgct gctggtgcat ctgctcaagt attgggttct gaaggtaaat
    31141 acgttcttgt tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta
    31201 cagttggtgt tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta
    31261 gccgttggaa aggtatccgc ccaacagttc gtggttctgt aatgaaccct aacgatcacc
    31321 cacacggtgg tggtgaaggt aaagcaccag ttggtcgtaa agcaccatct actccatggg
    31381 gcaaacctgc tcttggtctt aaaactcgta acaagaaagc gaaatctgac aaacttatcg
    31441 ttcgtcgtcg caacgagaaa taatattaaa ctagtcgctt aagcaactag taaatccgcc
    31501 agctcggtag cgctccatag gagtgcaagc cgctgtggta caacatttaa aggagaaaat
    31561 ataaaaatgg gacgcagtct taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa
    31621 gttgaagctc aagctaacga cgaaaagaaa aaagttatta aaacttggtc acgtcgttca
    31681 acgatcttcc caagtttcat tggttacact attgcagttt atgacggacg taaacacgta
    31741 cctgtttaca tccaagaaga catggtaggc cacaaacttg gtgaatttgc accaactcgt
    31801 acttacaaag gtcacgctgc agacgacaag aaaacacgta gaaaataagg agaacataaa
    31861 tggcagaaat tacttcagct aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat
    31921 cacgtcttgt tcttgataac atccgtggta aaagcgtagc cgatgcaatc gcaatcttga
    31981 cattcactcc aaacaaagct gctgaaatca tcttgaaagt tttgaactca gctgtagcta
    32041 acgctgaaaa caactttggt ttggataaag ctaacttggt agtatctgaa gcattcgcaa
    32101 acgaaggacc aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca
    32161 acaaacgtac agctcacatc actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg
    32221 gtcaaaaagt acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat
    32281 ggtatgctga aaaagaatac gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg
    32341 ttcaaaaaga acttgctgac gcagcagttt caactattga aatcgaacgc gcagtaaaca
    32401 aagttaacgt ttcacttcac actgctaaac caggtatggt tatcggtaaa ggtggtgcta
    32461 acgttgatgc actccgtgca aaacttaaca aattgactgg aaaacaagta cacatcaaca
    32521 tcatcgaaat caaacaacct gatttggatg ctcaccttgt aggtgaagga attgctcgtc
    32581 aattggagca acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc
    32641 gtgctggagc taaaggaatc aaaactcaag tatcaggtcg tttgaacggt gcagatatcg
    32701 cccgtgctga aggatactct gaaggaactg ttccgcttca cacacttcgt gcagatatcg
    32761 attacgcttg ggaagaagca gatactacat acggtaaact tggtgttaaa gtatggatct
    32821 accgtggtga agttcttcca gctcgtaaaa acactaaagg aggtaaataa ccaatgttag
    32881 tacctaaacg tgttaaacac cgtcgtgagt tccgtggaaa aatgcgcggt gaagcaaaag
    32941 gtggaaaaga agtagcattc ggtgaatacg gtcttcaagc tacaactagc cactggatca
    33001 ctaaccgcca aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta
    33061 aagtttggat taaaatcttc ccacacaaat catacactgc taaagctatc ggtgtgcgta
    33121 tgggatctgg taaaggggca cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga
    33181 tgttcgaaat cgctggtgta tctgaagaga ttgcacgtga agcgcttcga cttgctagcc
    33241 acaaattgcc agttaaatgt aaattcgtaa aacgtgaagc agaataagga gaaggcatga
    33301 aacttaatga agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa gaagaactcg
    33361 cgaagcgcga aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa gctgctactg
    33421 gtcaattgga acaaacagct cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa
    33481 cagttcaatc tgaagcgaaa taatagacta gggaaggaga aatttcaatg gaacgcaata
    33541 atcgtaaagt tcttgttgga cgtgttgtat ctgacaaaat ggacaagaca atcacagttg
    33601 tagttgaaac aaaacgtaac cacccagtct atggtaaacg tattaactac tctaaaaaat
    33661 acaaagctca tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt atcatggaaa
    33721 ctcgcccgct ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca
    33781 tcatctaatc aaacctgaaa ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa
    33841 gtcgcagaca acagcggtgc tcgcgaaatc ttgactatca aagttcttgg tggttcagga
    33901 cgtaaatttg caaacatcgg tgatgttatc gtggcatctg taaaacaagc tactcctggt
    33961 ggtgcggtta aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct
    34021 cgtcgtgctg atggttcata catcaaattt gacgaaaacg cagcagttat catccgtgaa
    34081 gacaaaactc ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt
    34141 ggcttcatga agatcgtgtc acttgctcca gaagtacttt aatttttagg aacaaactag
    34201 tcccctagct tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa
    34261 tgtttgtaaa aaaaggcgac aaagttcgcg taatcgctgg taaagacaag ggaacagaag
    34321 ctgttgtcct tactgccctt ccaaaagtaa acaaagttat cgttgaaggt gttaacattg
    34381 ttaagaaaca ccaacgtcca actaacgagc ttcctcaagg tggtatcatc gagaaagaag
    34441 cagctatcca cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg
    34501 gatacaaatt tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg
    34561 attaatcacg aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa
    34621 tgaagtagtt cctgctttga cagaacaatt caactactca tcagtgatgg ctgtgcctaa
    34681 agtagataag attgttttga acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct
    34741 tgaaaaagct gctgaagaat tggcacttat ctcaggtcaa aaaccactta tcactaaagc
    34801 taaaaaatca atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac
    34861 ccttcgtggt gaacgtatgt acgaattctt ggataaattg gtatcagttt cacttccacg
    34921 tgtacgtgac ttccacggtg tcccaacaaa atcatttgat ggacgcggga actacacact
    34981 tggtgtgaaa gaacaattaa tcttcccaga aatcaacttc gatgacgttg acaaaactcg
    35041 tggtcttgac atcgttatcg taacaactgc taacactgac gaagagtcac gtgcattgct
    35101 tacaggcctt ggaatgcctt ttgcaaaata atataggagg taaatctaat ggctaaaaaa
    35161 tcaatggtag ctagagaggc taaacgccaa aaaattgttg accgttatgc tgaaaaacgt
    35221 gctgcattaa aggcggcagg ggactacgaa ggtttatcta aattacctcg caacgcctca
    35281 ccgactcgtt tacataatcg ttgtagagtt acggggcgcc cacattcagt ttaccgcaaa
    35341 tttggtctga gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta
    35401 acaaaagcat cttggtaatt taagatatca agggtgtcaa aactccaagt aaaaatagga
    35461 aacttgacga agaaactaaa gtttctagga aagtttatct ttttcacaca gagtttagcc
    35521 cgggttcaat tgggcttgcc aatttgaacc cgagctacag ctttggcaaa aaagaccaat
    35581 ttgctttgga gcattgcttc tgcattaaat tgtctatttt tgctcgtgct gttacgctct
    35641 ttgtatcatg tattaactag caagtgcaac ttgcaaacta ctagtaagag gagaaaaaca
    35701 aaatggttat gactgaccca atcgcagact tcctaactcg tattcgtaat gctaaccaag
    35761 ctaaacacga agtacttgaa gtacctgcat caaacatcaa aaaagggatt gctgaaatcc
    35821 ttaaacgcga aggttttgta aaaaacgttg aaatcattga agatgacaaa caaggcgtca
    35881 tccgtgtatt tcttaaatac ggaccaaatg gtgagaaagt tatcactaac ttgaaacgtg
    35941 tttctaaacc aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa gttcttaacg
    36001 gacttggaat tgccatcctt tcaacttctg aaggtttgct tactgataaa gaagcacgcc
    36061 aaaagaatgt tggtggtgag gttatcgctt acgtttggta aaatcaagat acaaagctcg
    36121 taaagaacaa agcaaaatta ggaagttgga gaagtttgtt tacaaacaag ccaacttatc
    36181 tattttgcac agttcttaga gcgtgttcag ttcagctctt gaactaaata agtatctgaa
    36241 ccccgtgaaa actggccgtt ctggcctgac aatttaacag gagaaaataa acatgtcacg
    36301 tattggtaat aaagttatcg tgttgcctgc tggtgttgaa ctcgctaaca atgacaacgt
    36361 tgtaactgta aaaggaccta aaggagaact tactcgtgag ttctcaaaag atattgaaat
    36421 ccgtgtggaa ggtactgaag taactcttca ccgtccaaac gattcaaaag aaatgaaaac
    36481 tatccacgga actactcgtg cccttttgaa caacatggtt gttggtgtat cagaaggatt
    36541 caagaaagaa cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag gatctaaact
    36601 tgttttggct gttggtaaat ctcatccaga cgaagttgaa gctccagaag gaattacttt
    36661 tgaacttcca aacccaacaa caatcgttgt tagcggaatt tcaaaagaag tagttggtca
    36721 aacagctgct tacgtacgta gccttcgttc accagaacca tataaaggta aaggtatccg
    36781 ttacgttggt gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat gttgagtggt
    36841 tgatcatcaa ccaccaacct attttccaac tttgtgcata gcacacgatt taaaactaaa
    36901 gaggtgaaaa ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa acgtcaccgt
    36961 cgcgttcgcg gaaaactctc tggaactgct gatcgcccac gtttgaacgt attccgttct
    37021 aatacaggca tctacgctca agtgattgat gacgtagcgg gtgtaacgct cgcaagtgct
    37081 tcaactcttg ataaagaagt ttcaaaagga actaaaactg aacaagccgt tgctgtcggt
    37141 aaactcgttg cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt cgaccgcggt
    37201 ggatatctat atcacggacg tgtgaaagct ttggctgatg cagctcgtga aaacggattg
    37261 aaattctaat aggaggacac tagaaaatgg catttaaaga caatgcagtt gaattagaag
    37321 aacgcgtagt tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt cgtcttcgtt
    37381 tcgcagctct tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt actggtaaag
    37441 ctcaagaagt tccagaagca atccgtaaag cagtagatga tgctaagaaa aacttgatcg
    37501 aagttcctat ggttggaaca acaatcccac acgaagttct ttcagaattc ggtggagcta
    37561 aagtattgtt gaaacctgct gtagaaggtt ctggagttgc cgctggtggt gcagttcgtg
    37621 ccgttgtgga attggcaggt gtggcagata ttacatctaa atcacttggt tctaacactc
    37681 caatcaacat tgttcgtgca actgttgaag gtttgaaaca attgaaacgc gctgaagaaa
    37741 ttgctgccct tcgtggtatt tcagtttctg atttggcata agaaagggga taaaatggct
    37801 caaattaaaa ttactttgac taagtctcca atcggacgca ttccatcaca acgtaaaact
    37861 gttgtagcac ttggacttgg caaattgaac agctctgtta ttaaagaaga taacgctgct
    37921 atccgtggta tgatcacagc agtatctcac ttagtaacag ttgaagaagt aaactaatga
    37981 agttttaggg gatgtgcact gtaccatccc ctaaaactag atatagtcat ctatgatgac
    38041 atcgtatagg cgagttgatg ggggagacaa ccttttctcc cttatcggcg ctagcatttt
    38101 acaaaagagg agaaaataaa aatgaaactt catgaattga aacctgcaga aggttctcgt
    38161 aaagtacgta accgcgttgg tcgtggtact tcatcaggta acggtaaaac atctggtcgt
    38221 ggtcaaaaag gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt tgaaggtgga
    38281 caaactccat tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa cgctaaagaa
    38341 tacgcaattg tgaaccttga ccaattgaac gtctttgaag atggtgctga agtaactcca
    38401 gttgttctta tcgaagcagg aattgttaaa gctgaaaagt caggtattaa aattcttggt
    38461 aacggtgagt tgactaagaa attgactgtg aaagcagcta aattctctaa atcagctgaa
    38521 gaagctatca ctgctaaagg tggttcagta gaagtcatct aagagaggtg acctatgttt
    38581 tttaaattat taagagaagc tcttaaagtc aagcaggttc gatcaaaaat tttatttaca
    38641 atttttatcg ttttggtctt tcgtatcgga actagcatta cagttcctgg tgtgaatgcc
    38701 aatagcttga atgctttaag tggattatcc ttcttaaaca tgttgagctt ggtgtcgggg
    38761 aatgccctaa aaaacttttc gatttttgcc ctaggagtta gtccctatat caccgcttct
    38821 attgttgtcc aactcttgca aatggatatt ttacccaagt ttgtagagtg gggtaaacaa
    38881 ggggaagtag gtcgaagaaa attgaatcaa gctactcgtt atattgctct agttctcgct
    38941 tttgtgcaat ctatcgggat tacagctggt tttaatacct tggctggagc tcaattgatt
    39001 aaaactgctt taactccaca agtttttctg acgattggta tcatcttaac agctggtagt
    39061 atgattgtca cttggttggg tgagcaaatt acagataagg gatacggaaa cggtgtttcc
    39121 atgattatct ttgccgggat tgtttcctca attccagaga tgattcaggg catctatgtg
    39181 gactactttg tgaacgtccc aagtagccgt atcacttcat ctatcatttt cgtaatcatt
    39241 ttgattatta ctgtattgtt gattatttac tttacaactt atgttcaaca agcagaatac
    39301 aaaattccaa tccaatatac taaggttgca caaggtgctc catctagctc ttaccttccg
    39361 ttaaaggtaa accctgctgg agttatccct gttatctttg ccagttcgat tactgcagcg
    39421 cctgcggcta ttcttcagtt tttgagtgcc acaggtcatg attgggcttg ggtaagggta
    39481 gcacaagaga tgttggcaac tacttctcca actggtattg ccatgtatgc tttgttgatt
    39541 attctcttta cattcttcta tacgtttgta cagattaatc ctgaaaaagc agcagagagc
    39601 ctacaaaaga gtggtgccta tatccatgga gttcgtcctg gtaaaggtac agaagaatat
    39661 atgtctaaac ttcttcgtcg tcttgcaact gttggttccc tcttccttgg tgtgatttcc
    39721 attttaccga ttgcagctaa agatgtattt ggtctttctg atgttgttgc ctttggtgga
    39781 acaagtctct tgatcattat ctctacaggt atcgaaggaa tcaagcaatt ggaaggttac
    39841 ctattgaaac gtaagtatgt tggtttcatg gacagaacag aataaaagta tttactgaat
    39901 cagtaaatac tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt ggatctcccc
    39961 tcttctattt tgtttttaaa taggggtgaa aagacttttt gcttctattt aaaaataaaa
    40021 taaggagatc aaatcatgaa tcttttgatt atgggcttac ctggtgcagg taagggaact
    40081 caagcagcaa aaatcgtaga acaattccat gttgcacata tctcaacagg tgatatgttc
    40141 cgcgctgcaa tggcaaatca aactgaaatg ggtgttcttg ctaagtcata tattgacaag
    40201 ggtgaattgg ttcctgacga agttacaaat ggaatcgtaa aagaacgcct ttcacaagat
    40261 gatattaaag aaacaggatt cttattggat ggttacccac gtacaattga acaagctcat
    40321 gccttggaca aaacattggc tgaacttggc attgaactag aaggtattat caatattgaa
    40381 gtgaaccctg acagcctctt ggaacgtttg agtggccgta tcatccaccg cgtaactgga
    40441 gaaactttcc acaaggtctt taacccacca gttgactata aagaagaaga ttactaccaa
    40501 cgtgaagatg ataagcctga gacagtaaaa cgtcgtttgg atgttaatat tgctcaagga
    40561 gaaccaatca ttgctcacta ccgtgccaaa ggtttggttc atgacatcga aggtaatcaa
    40621 gatatcaatg atgtcttctc agatattgaa aaagtattga caaatttgaa ataaagcgtt
    40681 tttcgcactt gcaaaaatcc gctacaaatg ttatactgag atagtctgac ttataattgt
    40741 tgtctctgtg tctagaggca tcgaatcgaa atttatggag gtgcttttgc gtggcaaaag
    40801 acgatgtgat tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca atgtttacgg
    40861 ttgaacttga aaatggacat cagattttag caacagtttc tggtaaaatt cgtaaaaact
    40921 atattcgtat tttagcggga gatcgtgtta ctgtcgaaat gagtccatat gacttgacac
    40981 gtggacgtat cacttaccgc tttaaataat cgaaaaactt ggagggataa gaaatgaaag
    41041 taagaccatc ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt aatggtcgtg
    41101 ttatggtaat ttgcccagca aatccaaaac acaaacaacg tcaaggataa gatagaaagg
    41161 agaaaacatg gctcgtattg ctggagttga tattccaaat gacaaacgcg tagtaatctc
    41221 attgacttat gtttatggta tcggacttgc aacatctaag aaaattttgg ctgctgctgg
    41281 aatctcagaa gatgttcgtg tacgtgatct tacatcagat caagaagatg ctatccgtcg
    41341 tgaagtggat gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact tgaacatcaa
    41401 acgtttgatg gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac ttcctgtccg
    41461 tggacaaaac actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg cgattgctgg
    41521 taagaaaaaa taatatagga ggtaaaagtc ttggctaaac caacacgtaa acgtcgtgtg
    41581 aaaaagaata tcgaatctgg tattgctcat attcacgcta catttaataa cactattgtt
    41641 atgattactg atgtgcatgg taatgcaatt gcttggtcat cagctggtgc tcttggtttc
    41701 aaaggttctc gtaaatctac accattcgct gctcaaatgg cttctgaagc tgctgctaaa
    41761 tctgcacaag aacacggtct taaatcagtt gaagttactg taaaaggtcc aggttctggt
    41821 cgtgagtcag ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc aattcgtgat
    41881 gtgactccag tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt ataatcatcg
    41941 cattacactg cttttcgttt aagagggagt aactaaatga tcgagtttga aaaaccaaat
    42001 ataacaaaaa ttgatgaaaa taaagattat ggcaagtttg taatcgaacc acttgaacgt
    42061 ggctacggta caactcttgg taactctctt cgtcgtgtac ttctagcttc tctaccagga
    42121 gcagctgtga catctatcaa cattgatggt gtgttacatg agtttgacac agttccaggt
    42181 gttcgtgaag acgtgatgca aatcattctg aacattaaag gaattgcagt gaaatcgtac
    42241 gttgaagacg aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt aacagctggt
    42301 gacattttga cagatagcga tattgaaatt gtaaatccag atcattatct ctttacaatc
    42361 ggtgaaggtt cttctctaaa agcgactatg actgttaaca gtggtcgtgg atatgtacct
    42421 gctgatgaaa ataaaaagga taatgcacca gttggaacac ttgctgtaga ttctatttat
    42481 acaccagtta caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag caatgatggt
    42541 ttcgacaaat taacccttga aatcttgaca aatggaacaa ttattccaga agatgcttta
    42601 gggctttcag cacgtatttt gacagaacat cttgatttgt ttacaaatct tactgagatt
    42661 gctaagtcaa ctgaagtgat gaaagaagct gatactgaat ctgacgaccg tattttagat
    42721 cgtacgattg aggaactgga cttgtctgtg cgttcataca actgtttaaa acgtgccggt
    42781 atcaatactg tgcatgattt gacagaaaaa tctgaagcag agatgatgaa agtacgaaat
    42841 cttggacgca agagtttgga agaagtgaaa ctcaaactca ttgatttggg tcttggatta
    42901 aaagataaat aaaggaggaa tacatggctt accgtaaact aggacgcact agctcacaac
    42961 gtaaagcaat gcttcgcgat ttgacaactg accttttgat caacgaatca atcgtgacaa
    43021 ctgaagctcg tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact ctaggtaaac
    43081 gtggtgattt gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa atcgcatctg
    43141 aaaactatga tgaagcaact gataagtaca cttctactac agcacttcaa aaattgttct
    43201 cagaaatcgc acctcgttat gctgaacgta acggtggata cactcgtatc cttaaaactg
    43261 aaccacgtcg tggtgatgca gcgccaatgg cgatcatcga attagtataa aatcatcaat
    43321 tttgttgagt gttatgatga tggagtcttg tgctcttagt ctagctctgg tctaccgcta
    43381 ggatttcggt cctagcggga acactcatca taagttggga tagtagacgc ttgtttacga
    43441 aattgttttt ttcttaagaa caacttcgta agcaggcgtt tttgagtatt ttcgttagaa
    43501 ttatgctata ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga
    43561 attggagttt acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg
    43621 ttgcaggtgt ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa
    43681 ctgtcttgga tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt
    43741 ttacctatct tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata
    43801 ttcagagtgc agcgattttc gaagctatgt ataatatcta ggaggtcatc atggatatta
    43861 gacaagttac tgaaaccatc gccatgattg aggagcaaaa cttcgatatt agaaccatta
    43921 ccatggggat ttctcttttg gactgtatcg atccagatat caatcgtgct gcggagaaaa
    43981 tctatcaaaa aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg
    44041 ctgagttggg aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg
    44101 gggcagcgac agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggctgcga
    44161 aagagattgg tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa
    44221 agggagatga gattctcatc aattccattc ctcgcgcttt ggctgagacg gataaggtct
    44281 gctcgtcagt caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata
    44341 tgggacgaat tatcaaggaa acagcaaatc tttcagatat gggagtggcc aagttggttg
    44401 tattcgctaa tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg
    44461 aagcagatgt tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa cgtgctttgg
    44521 aaaaagttcg tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta
    44581 aaatcactcg tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt
    44641 ttggtattgt ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg
    44701 tccttgagga aatggggcta gaaacagttg gcacgcatgg aacgacagct gccttggccc
    44761 tcttgaacga ccaagttaaa aagggtggag tgatggcctg taaccaggtc ggtggtctat
    44821 ctggtgcctt tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct
    44881 ctcttaattt agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga
    44941 ttgccatccc agaagatacg cctgctgaaa ccattgcggc tatgattgcg gatgaagcag
    45001 caatcggtgt tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaagagaag
    45061 gcgatatgat tgagtttggt ggtctattag gaactgcacc cgttatgaag gttaatgggg
    45121 cttcgtctgt cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta
    45181 aaaattaaga aaataggaga aattttaagt tctatttaag attagatgtg tatactataa
    45241 tcattaaata aagacctcct aatattattt gaaacagata acactgaatt agtttgaatt
    45301 tgattttcat ctaatatctt tatttaatga actcctaaac tttttcataa taatctcctt
    45361 caaaagtcgc ctgtatgggt ggcttttatt ttatcattca tgatataata gaagcaaacg
    45421 gaggacggaa aatggtaaaa gtacgattgt atttggtacg tcatggcaag accatgttta
    45481 acacgattgg tcgcgcgcaa ggttggagcg atactccctt aactgctgaa ggtgaacgag
    45541 ggattcaaga gttaggaatc ggtttgcgag aatctgatct acagtttgag cgcgcttatt
    45601 cgagtgattc tggtcgtacc attcagacca tgggaattat acttgaagaa cttggcttgc
    45661 aggggaaaat cccttatcgc atggacaagc gtatcagaga atggtgtttc ggtagttttg
    45721 atggagccta tgatggcgat cttttcatgg gcattattcc tcgtatcttt aatgtggacc
    45781 acgttcacca attgtcttat gctgaactgg ctgagggctt ggtagaggtc gatacagctg
    45841 gttgggctga aggttgggaa aaactcagtg gccgaatcaa ggaaggcttt gaaataattg
    45901 caaaagaaat ggaagatcaa ggtggaggta acgcccttgt tgtcagccat ggaatgacta
    45961 ttggaaccat tgtttatctg attaatggca tgcatccgca tggtctagat aatggtagcg
    46021 tgacgattct tgaatatgag gacggtcagt ttagggttga agttgtcggt gaccgtagtt
    46081 accgagagct aggacgtgag aagatggaag aaggttctat ttaatcagtc tagacttgct
    46141 tgccatgagc tagggatttg ataagaatat caagataaga aaaaacagcc gagggtactc
    46201 ctttcggctg tttttgatgt ggaaaactaa agtgtaatgc tattgctttt agagattttc
    46261 ataaacaaga gcaaggaacc tactgttaga acagtcagga tagttgacaa ggctgcggct
    46321 acaccgtaat ttcctctgag aatctctgta taaatagcca cagtcattgt tcttgttttg
    46381 acattgtaga ggaggataga agtagagagt tttgaaatca ttgtgaccca agataagatg
    46441 gctccagaaa tgataccaga tagcatcatt ggagttgtaa tcttagcaaa gatattgaga
    46501 cgactacttc ctaagctttc agcagcttct tcaatacttg gtgctatttg ttgtaagcta
    46561 gcaacagatg agcgaatagt ataaggtaat cttctgacag atagagacat aatcaagatg
    46621 aaagcagtcc ctgtaatcat aagaaatcca cttccaaata gaccagtatt gaaggaagaa
    46681 atgaaggcaa tccctagaac ggttcctggt acaatataag gtaccatact gaggctgtca
    46741 attaagtttg taaacaaatt ccgttttcta acggctaggt aggagataaa tgtcgcaaat
    46801 agaacaacta gaactaaggc aatcaaaggg atacgaatgg tattgaaaat agcagatccc
    46861 atacgattga aagctacctt gtaactgttt ggagaataac ctttaacaaa taccatacct
    46921 gatgttttta ggaaagaggt ataaattaag tagatttgag gtaaaacaga gataaagata
    46981 attccgtaga ctgttgcata aatggcagcc atttttcctt ttgtagtttt tttaggctca
    47041 attggatgga gcagattcat gctgaaactg tagcggtttg caatgtgttt ttggataagg
    47101 aaaattgcca aggcaatgat aatcgccata attgcaaaag cagaatttcc tccaacctcg
    47161 ctaataaatt gggtataaat caggacaggg aaagtccgat atccttcgcc aatcaacata
    47221 ggcgttccaa agtctgagaa tgctctcata aatacaagca aggagctgct agtaaggttg
    47281 aaactaggag aggtaaaaca accgttacga taggtttaaa tccgaaggac cccatgcttt
    47341 cagctgcttc aagtagagaa ttgtcaatac tgttcattgt tccagcaaca tatagaaata
    47401 ccagtgggaa tagttgcagt gtaaagacaa gtatacttcc tttgaatcca taaatatcga
    47461 tagctggaag atgaagggca tttgtcaaaa atttagtgat gacctcattt cgtctcagca
    47521 agagaatcca ggagtaggct cctacgaaag gagctgacat ggaagcaatg ataatcaata
    47581 tttgtagaaa tttcttcccc ttgaagtcat acatagagaa gagataagct aatagggttc
    47641 ctacaactaa ggaagtgaca gtagcggtaa tggaaaccct gaaactgttg actagtgtct
    47701 cagagtagta ggttttacta aagaaagtga caaaattagc tagtgagaat tgtccttcat
    47761 gtataagtgc ttgcttgagc acggtaacga taggataaac gagaaagaca agataggtaa
    47821 gaaagatgaa gaaagaggaa gctgtccaaa tatttagttt tttacattcc atggttgact
    47881 ccttttatca ggttttggga accatctgca gaaaagatgt ttaatttttg cgtattgatt
    47941 cgtagacgaa tacgattgcc tttttgtagt tcttcttcaa aagttgattc ttcactaact
    48001 tgaatttttg aggcaaaacc tgtctcaatg aaatactccg tatttagtcc aagatagacg
    48061 ctatcgctaa tagttccttc aatatctcca gattcatctt tgataaactc ttcgggacga
    48121 atgcttacat gaatagcttg ctcctcaacc tgatcaagag ctggcattcg aagggcatag
    48181 ccatctgaaa agacgatata agcgccgtcg ctccgttttt caagattggc agggataata
    48241 tttgtgcgtc cgataaaggt tgccacaaac tcattagctg gtttatgata gagttctttt
    48301 ggtcggccga tttgttggat caccccatct ttcataacag caatttggtc tgaaatagcc
    48361 atggcttctt cttggtcgtg ggttacataa acagttgtaa ttcccacttc gtgttggatt
    48421 tctcggatgg cttgacgcat atccaagcga agtttggcct ccagattact aagtggctcg
    48481 tccatgagga gaacacttgg attaaccgct aaggcgcatg ccaaggtgac acgttgttgt
    48541 tgtccaccac tgagtttatc gggttttcga tccgcatatt gagcaatttg catgagttca
    48601 agatacttgt tggtctgttg aatcaattct tcttttgcat aagaccaaaa gcaacgttgt
    48661 ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccatcccg atattgcgtt
    48721 tgctgggttc catattattg atttttgtat catcgaagta aaattctcaa tctttgatac
    48781 tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa gctccaagaa
    48841 gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca gggacatcgt
    48901 ggtagatttt tttggcgtta ataattttga tctcactcat agtgaacctc ttttactgtt
    48961 tagattggat atctgtaaag acttcgttgt atttcttaac gatatctgat ttattcttga
    49021 tgacataatc ataatcttca gtgagtgttt tgattttgtc aattggtttc atgttttcgc
    49081 ttgttttagc atttttacga acaggacggt tagtagtggt tgtaccaagt gtatcttgta
    49141 cttcttgaga gataataaaa tcgataaatt tcttggcatt ttccatattt ttagattttt
    49201 taacgatagc agcactagca ggtaggaaga cggttccttc ttttggatag actaccttaa
    49261 tgttagctcc gtcatttaag agtttaactg ctggatcttc ataagagaga ccaacagtca
    49321 tttctccatc agcgactgct ttatagacac cagatgaact taaaccgatt ttatagta
//
LOCUS       DAVBOM010000009        44501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBOM010000009 DAVBOM010000000
VERSION     DAVBOM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.009"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..218
                     /locus_tag="VQ878_000533"
     CDS             <1..218
                     /locus_tag="VQ878_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3094932.1"
                     /translation="VIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWA
                     HIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            complement(253..1050)
                     /locus_tag="VQ878_000534"
                     /pseudo
     CDS             complement(253..1050)
                     /locus_tag="VQ878_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1315..1551
                     /locus_tag="VQ878_000535"
     CDS             1315..1551
                     /locus_tag="VQ878_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET3094933.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1782..3068
                     /locus_tag="VQ878_000536"
     CDS             1782..3068
                     /locus_tag="VQ878_000536"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET3094934.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(3300..4448)
                     /locus_tag="VQ878_000537"
     CDS             complement(3300..4448)
                     /locus_tag="VQ878_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3094935.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(4623..5435)
                     /locus_tag="VQ878_000538"
     CDS             complement(4623..5435)
                     /locus_tag="VQ878_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET3094936.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(5473..5853)
                     /locus_tag="VQ878_000539"
                     /pseudo
     CDS             complement(5473..5853)
                     /locus_tag="VQ878_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(5866..6129)
                     /locus_tag="VQ878_000540"
     CDS             complement(5866..6129)
                     /locus_tag="VQ878_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3094937.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6129..6362)
                     /locus_tag="VQ878_000541"
     CDS             complement(6129..6362)
                     /locus_tag="VQ878_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094938.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(6362..6730)
                     /locus_tag="VQ878_000542"
     CDS             complement(6362..6730)
                     /locus_tag="VQ878_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3094939.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7015..7161
                     /locus_tag="VQ878_000543"
     CDS             7015..7161
                     /locus_tag="VQ878_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094940.1"
                     /translation="MNEEDLKELLELLATDYGRGYLDGVVGGLSMLLKISKEAEKYRK
                     EKYE"
     gene            7205..7579
                     /locus_tag="VQ878_000544"
     CDS             7205..7579
                     /locus_tag="VQ878_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094941.1"
                     /translation="MIETLEIKINKKTYFISARADVPVRYKVMFGRNLFDDFSKIKNN
                     KDETLSLCLLFCMTDKSSEEFCKFFIENNSYITSRHHYEAIRLFEKHFIFKPVTYSLE
                     DIVQILTIYLENTKTQIGGKNE"
     gene            7572..7775
                     /locus_tag="VQ878_000545"
     CDS             7572..7775
                     /locus_tag="VQ878_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3094942.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQVELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            7792..7989
                     /locus_tag="VQ878_000546"
     CDS             7792..7989
                     /locus_tag="VQ878_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094943.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            8000..8161
                     /locus_tag="VQ878_000547"
     CDS             8000..8161
                     /locus_tag="VQ878_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094944.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(8156..8581)
                     /locus_tag="VQ878_000548"
     CDS             complement(8156..8581)
                     /locus_tag="VQ878_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094945.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            8635..9348
                     /locus_tag="VQ878_000549"
     CDS             8635..9348
                     /locus_tag="VQ878_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET3094946.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKA
                     RVVVCLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            9361..9618
                     /locus_tag="VQ878_000550"
     CDS             9361..9618
                     /locus_tag="VQ878_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3094947.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            9704..10024
                     /locus_tag="VQ878_000551"
     CDS             9704..10024
                     /locus_tag="VQ878_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094948.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRFL"
     gene            10040..10336
                     /locus_tag="VQ878_000552"
     CDS             10040..10336
                     /locus_tag="VQ878_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094949.1"
                     /translation="MQELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRYMTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            10329..11156
                     /locus_tag="VQ878_000553"
     CDS             10329..11156
                     /locus_tag="VQ878_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET3094950.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            11296..12066
                     /locus_tag="VQ878_000554"
     CDS             11296..12066
                     /locus_tag="VQ878_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3094951.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            12081..12275
                     /locus_tag="VQ878_000555"
     CDS             12081..12275
                     /locus_tag="VQ878_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094952.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            12275..12502
                     /locus_tag="VQ878_000556"
     CDS             12275..12502
                     /locus_tag="VQ878_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094953.1"
                     /translation="MLELYFVYNGHCKFFLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            12629..12796
                     /locus_tag="VQ878_000557"
     CDS             12629..12796
                     /locus_tag="VQ878_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094954.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            12783..12992
                     /locus_tag="VQ878_000558"
     CDS             12783..12992
                     /locus_tag="VQ878_000558"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094955.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKAEELEYDGRVKAKS"
     gene            12964..13293
                     /locus_tag="VQ878_000559"
     CDS             12964..13293
                     /locus_tag="VQ878_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094956.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            13283..13708
                     /locus_tag="VQ878_000560"
     CDS             13283..13708
                     /locus_tag="VQ878_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3094957.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELVRQIFLQDLEQLDKPQPVKV
                     PQCVAEYIEFKKKNNFHVYGLAWLNGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYF
                     FTKSFSLDDVIYSHTRKELEAANFGWVFDCPGIEIEEVE"
     gene            13708..14222
                     /locus_tag="VQ878_000561"
                     /pseudo
     CDS             13708..14222
                     /locus_tag="VQ878_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            14219..14608
                     /locus_tag="VQ878_000562"
     CDS             14219..14608
                     /locus_tag="VQ878_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094958.1"
                     /translation="MIPKFRVWHHELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPAVYLKG
                     LGDGYAWTEYEEIIGNIYENPELLEDK"
     gene            14608..14844
                     /locus_tag="VQ878_000563"
     CDS             14608..14844
                     /locus_tag="VQ878_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET3094959.1"
                     /translation="MNPEIIDNINKPSHYQGANGLEAIDVVHNFVGSLSGASAFFWGN
                     AIKYMLRFQKKNGLEDLKKARKNLDWLIEEMEHE"
     gene            14841..14999
                     /locus_tag="VQ878_000564"
     CDS             14841..14999
                     /locus_tag="VQ878_000564"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094960.1"
                     /translation="MNTHCMKATPLLPWGRLRKSAKKQELLNGASISEFAIEDICTFF
                     GIEIQERK"
     gene            15211..15612
                     /locus_tag="VQ878_000565"
     CDS             15211..15612
                     /locus_tag="VQ878_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3094961.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLLSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            15801..16343
                     /locus_tag="VQ878_000566"
     CDS             15801..16343
                     /locus_tag="VQ878_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3094962.1"
                     /translation="MEFVSPIKDNDNIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            16507..16698
                     /locus_tag="VQ878_000567"
     CDS             16507..16698
                     /locus_tag="VQ878_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094963.1"
                     /translation="MVKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKWNNFFKESE"
     gene            16818..17138
                     /locus_tag="VQ878_000568"
     CDS             16818..17138
                     /locus_tag="VQ878_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET3094964.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            17276..17668
                     /locus_tag="VQ878_000569"
     CDS             17276..17668
                     /locus_tag="VQ878_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET3094965.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            17661..19391
                     /locus_tag="VQ878_000570"
     CDS             17661..19391
                     /locus_tag="VQ878_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET3094966.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            19399..19617
                     /locus_tag="VQ878_000571"
     CDS             19399..19617
                     /locus_tag="VQ878_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094967.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            19635..20837
                     /locus_tag="VQ878_000572"
     CDS             19635..20837
                     /locus_tag="VQ878_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3094968.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            20821..21396
                     /locus_tag="VQ878_000573"
     CDS             20821..21396
                     /locus_tag="VQ878_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET3094969.1"
                     /translation="MQKRNSYRATQFQTREEESGDLILSGYFIKFDEETELWPGYCEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFNL"
     gene            21393..22565
                     /locus_tag="VQ878_000574"
     CDS             21393..22565
                     /locus_tag="VQ878_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET3094970.1"
                     /translation="MNKLLILGARMRNKADKVVELEESIKELNKRSELEAKKLEQAGT
                     DEEVSAVEKNLEDIQKESDEKEAEKEQLEKEIEDLKNQVEELNRKAPTYPSQEKRGGQ
                     KLERRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTDGVMVSIDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGDNTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            22577..22867
                     /locus_tag="VQ878_000575"
     CDS             22577..22867
                     /locus_tag="VQ878_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094971.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            22870..23151
                     /locus_tag="VQ878_000576"
     CDS             22870..23151
                     /locus_tag="VQ878_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HET3094972.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            23138..23437
                     /locus_tag="VQ878_000577"
     CDS             23138..23437
                     /locus_tag="VQ878_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET3094973.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            23434..23781
                     /locus_tag="VQ878_000578"
     CDS             23434..23781
                     /locus_tag="VQ878_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3094974.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            23778..24101
                     /locus_tag="VQ878_000579"
     CDS             23778..24101
                     /locus_tag="VQ878_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094975.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            24113..24691
                     /locus_tag="VQ878_000580"
     CDS             24113..24691
                     /locus_tag="VQ878_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3094976.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            24703..25122
                     /locus_tag="VQ878_000581"
     CDS             24703..25122
                     /locus_tag="VQ878_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094977.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMSQNQLAKKSSQ"
     gene            25400..28159
                     /locus_tag="VQ878_000582"
     CDS             25400..28159
                     /locus_tag="VQ878_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET3094978.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     ESELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAQALDLTSRATRAAADGAAFYDKSIESVSESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFNSLPDPVKDFVVILGTV
                     VTAVGVIAPIFLTLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILAVINTVVSEISDFIMSIFGTVVTWWTENQELIRTSAETVWN
                     AIYTVISTILDILGPLLQAGWDNIQLIITTTWEIIKIVVETAINVVLGVIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            28156..28878
                     /locus_tag="VQ878_000583"
     CDS             28156..28878
                     /locus_tag="VQ878_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3094979.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKYFKDSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            28879..32100
                     /locus_tag="VQ878_000584"
     CDS             28879..32100
                     /locus_tag="VQ878_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3094980.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALARMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRSSGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAR
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKQTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLDA
                     GVRSLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYT
                     ATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFY
                     AKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQ
                     EGTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRAN"
     gene            34096..35478
                     /locus_tag="VQ878_000585"
                     /pseudo
     CDS             34096..35478
                     /locus_tag="VQ878_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            35459..35662
                     /locus_tag="VQ878_000586"
     CDS             35459..35662
                     /locus_tag="VQ878_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094981.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            35665..36017
                     /locus_tag="VQ878_000587"
                     /pseudo
     CDS             35665..36017
                     /locus_tag="VQ878_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36027..36443
                     /locus_tag="VQ878_000588"
     CDS             36027..36443
                     /locus_tag="VQ878_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET3094982.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            36447..36782
                     /locus_tag="VQ878_000589"
     CDS             36447..36782
                     /locus_tag="VQ878_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3094983.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRVVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            36782..37738
                     /locus_tag="VQ878_000590"
     CDS             36782..37738
                     /locus_tag="VQ878_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3094984.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(38008..38187)
                     /locus_tag="VQ878_000591"
     CDS             complement(38008..38187)
                     /locus_tag="VQ878_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094985.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(38329..38478)
                     /locus_tag="VQ878_000592"
     CDS             complement(38329..38478)
                     /locus_tag="VQ878_000592"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094986.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            38760..39227
                     /locus_tag="VQ878_000593"
     CDS             38760..39227
                     /locus_tag="VQ878_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET3094987.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            39260..39357
                     /gene="ffs"
                     /locus_tag="VQ878_000594"
     ncRNA           39260..39357
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ878_000594"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            39414..39857
                     /locus_tag="VQ878_000595"
     CDS             39414..39857
                     /locus_tag="VQ878_000595"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET3094988.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            39859..40374
                     /locus_tag="VQ878_000596"
     CDS             39859..40374
                     /locus_tag="VQ878_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3094989.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            40388..41749
                     /gene="radA"
                     /locus_tag="VQ878_000597"
     CDS             40388..41749
                     /gene="radA"
                     /locus_tag="VQ878_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET3094990.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFFIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            41822..42319
                     /locus_tag="VQ878_000598"
     CDS             41822..42319
                     /locus_tag="VQ878_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET3094991.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            42344..42538
                     /locus_tag="VQ878_000599"
     CDS             42344..42538
                     /locus_tag="VQ878_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3094992.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFLALFYM
                     IPALYFLFRIGKNGNCQRRF"
     gene            42520..43143
                     /locus_tag="VQ878_000600"
     CDS             42520..43143
                     /locus_tag="VQ878_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET3094993.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            43288..44256
                     /locus_tag="VQ878_000601"
     CDS             43288..44256
                     /locus_tag="VQ878_000601"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3094994.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(44393..44501)
                     /locus_tag="VQ878_000602"
                     /pseudo
     CDS             complement(44393..44501)
                     /locus_tag="VQ878_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        13874 a         7642 c        10190 g        12795 t
ORIGIN      
        1 cggttattat tatggataat gcaagattcc atagaatggg gaagttagaa cttttatgcg
       61 aagagtttgg gcataaactt ttacctcttc ctccctactc acctgagtac aatcctattg
      121 agaaaacatg ggctcatatc aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct
      181 tttacgaggc ttttttatcc tgctcttgtt tcaattgact atattagagg cgagacattt
      241 ttcggttctt tgtcaactgt agtgggttga agaaagcgaa gatctagaaa ggacaaattt
      301 cgtcctttct tttttgaagt tttcaaagtt cctaaaacca aaggcattgt gcttgataag
      361 tttgatgaga ttattggtgg cttccagttt ggcgttggaa taaggtaatt gaagggcgtt
      421 gacgattttc tctttatctt tgaggaaggt tttaaacaga gtctgaaaaa gaggtggaaa
      481 agcaagagct gatagagatt atagtggtgt ttcaagtctt cggaatagct caaaagttta
      541 tctagaattt ctttattagt caagtgcata cgaaaagtag ggcgataaaa tcgtttatca
      601 ctcagtttct gactatcttg ttgaatgagc tttcagtatc gcttgatagc cttgtattca
      661 tgggatttcg gatgatggct tgtgttctgc tctcaagaac agttatgata ttgagcttat
      721 caaagtcttg agcaataaag ctcatttcca tctcccgatt gaaacagtca ctccccggac
      781 tgtttcaacg tcctaggaca taatctcagg aagacgcgaa aaatcatgct caaagtgaaa
      841 atcattgttc ttgcgaatga cagttgaagt tgaaatagac aactgatgat caatgtcggt
      901 catagaagtc tttttaatta gcttctgagc aatcttttgg ttgatgatac aaggaatttg
      961 atgattcttc ttgacgatag aagtttcagc gaccatcatt tttgaacagt gatagcactt
     1021 aaaacggcct tttctaagaa gaattctagt ttgaattttt tatactagaa aatcagaacc
     1081 ataataccta tataaaaata ttatagttct aataggattt acccaaaagt tttaaggcgg
     1141 tctttttaga actttaatcg tttgaaattt aggtagcaaa tttgtttcta ttttgtcaac
     1201 ttttcctatt tttatcttgt tgaggctggt attttaacaa ttcaggaatt gatagtgaat
     1261 gtgtaaaatt ttttgttaga ataagtttat aaaaaagaaa aggagtattt gattatgtta
     1321 caaaaaattt atgagcagat ggctaatttc tatgatagta ttgaagaaga gtatggtcct
     1381 acatttggtg ataattttga ctgggaacat gttcatttta aatttttaat ttattattta
     1441 gtgagatatg gcattggttg tcgtagggat tttatcgttt accattatcg tgttgcttat
     1501 cgtttgtatc ttgaaaaatt ggtaatgaat cggggtttta tttcttgttg aggtaatttt
     1561 agtaaatttc cgaactaatt tactctttta tggaaagata atagtaaata gctagtaatt
     1621 tttctaaatc attttttaat agttggaaat agcaaatctt tctattgttt cttcttgata
     1681 aaaaggcgat tttttattat aataaattgt aagatataat tgcaggtgag agtcctgcca
     1741 tgtatgtgag aaaggaagag cctgagggct cagacaaaat tatgacttca gttgttgttg
     1801 taggtaccca atggggtgat gaaggtaaag ggaagattac agacttcctt tcagcgaatg
     1861 cagaagtgat tgcacgttac caaggtggtg ataatgctgg tcacacgatt gtgattgacg
     1921 gtaagaaatt taagttgcac ttgattccat ctgggatttt cttccctgaa aaaatatctg
     1981 tcattgggaa tggtatggtt gtaaatccta aatctcttgt aaaagagttg agctatcttc
     2041 atgaggaagg tgtaacaact gataacttac gtatttctga tcgtgcgcat gttattttgc
     2101 cttatcatat cgagttggat cgcttgcaag aagaagctaa gggcgacaat aagattggta
     2161 cgacaattaa gggaattggt ccagcttata tggacaaggc tgctcgtgtt ggaattcgta
     2221 ttgcagatct tttagataaa gatattttcc gtgagcgttt agaacgtaac cttgctgaaa
     2281 agaatcgtct ttttgaaaaa ttgtatgaca gtaaagcgat tgttttcgat gatatttttg
     2341 aagaatatta cgaatatggt caacaaatca agaaatacgt gatagataca tctgttatct
     2401 tgaatgatgc gcttgataat ggcaaacgtg tgctttttga aggtgcacaa ggtgttatgc
     2461 tagatatcga ccaaggtact tatccatttg ttacgtcatc aaaccctgta gctggtggtg
     2521 tgacaattgg ttctggtgtc ggtccaagca agattgacaa ggttgtaggt gtatgtaaag
     2581 cttatacgag tcgtgtagga gatggtcctt tcccaactga gttgtttgat gaagtgggag
     2641 aacgtatccg tgaagtgggt catgaatatg gtacaacaac tggtcgtcca cgtcgtgtag
     2701 gttggtttga ctcagttgtg atgcgtcata gccgtcgtgt ttctggtatt actaaccttt
     2761 ctttgaactc tattgatgtt ttgagcggtt tggatactgt gaaaatctgt gtggcctatg
     2821 atcttgacgg tcaacgtatt gactactatc cagctagtct tgagcaattg aaacgttgca
     2881 agcctatcta tgaagagttg ccaggttggt cagaagatat taccggagtt cgcaatttgg
     2941 aagatcttcc tgagaatgcg cgtaactatg ttcgtcgtgt gagtgaattg gttggcgttc
     3001 gtatttctac tttctcagta ggtcctggtc gtgaacaaac aaatatttta gaaagtgttt
     3061 ggtcctaaga gatttttaag atttgtttaa gataggtcgg gtatactata gacagttata
     3121 agaagacctc ctaacttgtt gtaacaaata tcctaaactt ttctttttca taataatctc
     3181 ccttaactcc acccaatcag gtggagtttt ttagctctat ttcaggcttt tggggactat
     3241 tctaaaaata atttttcgat atttttcgga ttttggtcgg ggaattggcg gggacttttt
     3301 tagcgaatat gactaagaaa taggtctgtt gtcgcttcag caagttcgtc ctctacttga
     3361 ttgtaacgat ccgtcatata aacctttgta tgccccagcg cctggcttaa ttgttcaagc
     3421 ggaacccctg caataatgct ttgagtcgtg aagaagtggc gcatcatgtg aggtgttaca
     3481 tgcaatcctg ttgcttcatt cactagattg aagtttctat ttagctgatt tggattgatg
     3541 agaccacctt tctcgttgat agttatataa tccttgtgct gttccttgat aattcctaac
     3601 tttcgcttaa tcttagaagc ttcagctatc agataataga tcaggtctgt tccgatatca
     3661 tcaaggcaga catatcgctc tgaatccttc gttttaagcc ctcctttccc ttttaaggtc
     3721 tggttgcttc gactgtctct aagatgcagt atagcccgtc cgctgtcgtt ctgagtgatg
     3781 tccattggac gcaatccaaa gacttctcct cttctcaatc caaaaattgt cagataggtc
     3841 agagcgtaga attgttttgg cataatctct tctgcctttg ctatccaagt cttgaactct
     3901 ttgagagtca ctttcttgtt tgcagcaggg atatcactct ggccgatgaa aacacctttc
     3961 aagcgatttg agagcagatt tccatttttg acggcatcat tcagcaatgc catgaagctg
     4021 gaattgaggg tttgaacagt gtatctggta tggttctgca acttttcagc gataaatagt
     4081 tcatactcat ttctatccaa atttttaagc aggatagaac caaactttgc cttgatatgg
     4141 ttcttataga gattgtcatt gaggtagtag gaagtgtcat tccagcgccc tgttgacaat
     4201 ctcttttcag aatagatatc ccaatattga tcaagcgtta gattcgtatt gatacctaat
     4261 tcttgttctt ggatttgttg ctcaagctct accaaggctg cacgagcttg agggagagtt
     4321 gtgaaaccac ttttactttt ttctcttttt ttacctcgga agaaaaaaga acgtctgaca
     4381 tagtaacgct tgcctttagc agtctcatag taatagatat ttgggtattt tgttttatta
     4441 tatttcattg tattctcctt gtttatcggc ttctggacaa ggtctaaaca ttgagaatat
     4501 tgacatcacc cctttcatgg tgtaaaatag ggtatagaaa agaggccttt ttaatggctg
     4561 attttttata agggtaagct tcacaatcaa actttggcga gggcgattgt ggggcttttt
     4621 ttttattttc tgaatagttt gtatagttta tacaaactcc aagctgtcaa agggactgca
     4681 aggaatggag cgattggaat accaacaact ccaaaaaaga ctaagaaaag atacagtgct
     4741 gaaaatatga ttttattggc aggaagtttt ttcttaggag atgtttctga aagattaatc
     4801 tcgtttacta tatcagcgac actgtcacta acaatatttt gttcaatatg ttcagtttca
     4861 gttgttttag tttcaatagc ttcagtttcc gtaacttctt tattggaaat gttatcatca
     4921 attatctcag atgattcgct ctgaattact tctttttgtg aagaatcaac aatggtaagg
     4981 taaatttcaa aaccaacatc caaatcatta tttgtgacaa ctttttcttc atactcgtcc
     5041 cattctttat atgggccacc ttttatctct ccctctatta caaagttata ttttttatta
     5101 tcaaaatatt ttcgtattgt tttagcaatg gttgcaggaa catatcctac atgattatca
     5161 aatatcaaaa cttttatagc attaggatca tatctattat ctacttctgg aacgagctca
     5221 atattgaaaa agtctaaatc ttgatatttg aaaactttca gaccatattc ttcaagttct
     5281 tctctaagtt ccttagttga taaattgcta tagtactttg catattctgg gattccgtta
     5341 tcttcagcaa tcatattgca agcttctttt actgcttttt tatattttgt cactccagcg
     5401 actctgaata atattttttc aacagtcttt tgcatatatt tcccctctat ataaatatct
     5461 tcaatgcaat ttttaattta ctaatgccaa gtactcttcc ttgaccatga cttcattagt
     5521 catagttttt agattgtagt aagacatgaa tttgaggtaa tcaaactctg tggggtcgtc
     5581 taagctttct agtgcgtctt tcacgagatg atggatcata ttcctatcag cttcgttttc
     5641 acagcgtagg cgagcgtttt ggtactctga gcgtgtatgg tctttgtgtc cgagttagtg
     5701 tagggcgact tggatttgtt gttcaggagc taagttgtgg tcaatagcga gtacgtttgt
     5761 gtctggattg tagaaaccgc tactgtgcca gtttgaaccg tcgaagagac aaagctctac
     5821 ttgatattct tcgcagagtt tagcgagtat catagttctc cttcgttatt tataaacatc
     5881 tctgcggtgg gcgatttcca cggctaggac gactagttta tcgtcttgga tatcacagat
     5941 gatgcggtaa ttctctactc tgtatcgcca gtaacctgca aggttggctt ttagtgcttt
     6001 tccgtgttgt cgtggattgg tcgtgttttc aatgttttta gcaagccagg ataggatttg
     6061 ttttctggtt ggggtatcta gttttttaag ttgcttgaga gcttttttat caatatctag
     6121 ccgatacatt aagcaatatc ctctcgagat agtcctagtt catccaagac ctcatccatg
     6181 gtataagtag ctgggtcggc taaatactcc atataggctt ggtcggctgc tcgtgcgtct
     6241 tcgatatctt ccatgagtac catgaagtcg tcaaaatcca tggttgttgt gtcgataccg
     6301 tgtttggtta ggtagtccgt gatgtaggag tttttttctg tgaaattgat cgtgatagtc
     6361 attagcgttc tcctttgctt ttgaagtggg cggatagaac ggatgtgatg aagtcgatat
     6421 catcttcatt tagtggtttt ccgtcaaata acatggtgtt ggctgctgct ttgcgtaagt
     6481 ctatgatttg tccatttact tgagcaaatt catcacttcc agcgatagca ggattatctg
     6541 tccgtccgag taggtagtca gcacttacat taaaataatc agctatttct tttaaaactt
     6601 ttgaactagg attacttctt tttaatcgat ataaagtatt agttccataa ccaagttttt
     6661 cttctaaaat atttatagaa atcccctgtt tatcagctaa ttcttttatt ttatcgaatg
     6721 ctacaaacat taatttttca acctttctaa gcaaacgaaa aataatttta aaatatttgt
     6781 agaaaatagt tgacttattt agtcaaatgt tttaaaataa tattcgtaag ctaaagagtt
     6841 agcgaactag acaactaaaa aataaagcct tacaaaactg attggcgtcc gtttactgta
     6901 ggtaaaactt acttttagta ggtcttttct ctatgttttt attttaaaac atttgactag
     6961 agttgtcaag aagttcgcta actttttaga taatttttta aaaggaggtc agggatgaac
     7021 gaagaagacc tgaaagaatt attggaactc ttagcgacag attatgggcg agggtatcta
     7081 gatggagtag ttgggggact ttcaatgctt ttgaaaattt caaaagaagc agagaaatat
     7141 agaaaggaaa aatatgagta aagcaaaatt attagtcaca taaagtaggt aaacgaggta
     7201 ggaaatgata gaaacactgg aaataaaaat aaacaaaaag acatacttca tatctgcaag
     7261 ggcagatgtt ccagtcaggt ataaagttat gtttggcaga aatctcttcg atgacttttc
     7321 gaaaataaaa aacaataaag atgaaactct atcactttgt ctattatttt gtatgacaga
     7381 caaatcgtca gaagaattct gtaaattttt tattgaaaat aattcatata taacaagtag
     7441 acatcactat gaggcaataa gattatttga aaaacatttt atctttaagc ccgtaacata
     7501 ttcactagag gacatagttc aaatcctaac aatatatcta gaaaatacta aaacacagat
     7561 tggaggaaaa aatgagtaaa gaactaaaaa taattaaggc taaaattaaa actcgtttga
     7621 ttgagttgga tatgactcaa gtcgaattgg caaaacaagt atctgtagca tcatcagtta
     7681 tttcagagtt gctgaagtat ggaaaaggaa gtgattatgt gaaagaaaaa gtcgtagata
     7741 ttttgggtat tgaaaaccct tgggaaaata gttagagcat gaggaaatag tatgaacaac
     7801 gcagcgcaaa aagtaacacg gattgacaaa gatgcctggg agattgctac ggagctggcg
     7861 aacgagtacg gcgtatctat ttgtcacatc atcagcgaga gcgtccgcta ctgtgcagag
     7921 aatgccgaat ttaaggagat ggacgttgtc gttaaacgat tggtagtcgg cagtaaggtg
     7981 ctggagtagg agggtggaga tgaatgaact agtatggttt tactttgttg tcataatcaa
     8041 tcttatcatt ggttttgcta catactacgc tagcaaaaga gatagagaaa agcgcatcaa
     8101 cgggtttaaa aaaatacaag atgatgagct tgaaagagtt agaaataaat ttaatttatg
     8161 attttttaga agtcttttga ataaatcttt tatttaagtt ttgtttgcta ttgcttgctt
     8221 tattagctat ttttaaagct ttgtcaaaat caacctcgcc tgtaaaaact ttgtaggtaa
     8281 gatcattcat cttcatagac ttgtcggttt cagtatcaag ctgagatacc ttctcaagtt
     8341 cttgcaaccg taattcatga gcttgtttga ttttttcaag ttcaaaggca tgttgctgtt
     8401 ttagagtatc tatctgatga tgaaattctc tttcgagttt ttcaacagta tgtgaatgtt
     8461 ctttggcttg tttttcaatc tcagctttat tgttagcttt tgatgcgaca tatgaccata
     8521 accctgatat tattgcaaga ataatactaa tcacaggttg aataagagct tgatattcca
     8581 taagatttct ccaatcgttt tattttaatt ataccaaatt tagaaaggaa ctttatgaac
     8641 gaaattttta attttcacgg gcaggaagtc cgtactttga tcattgatga cgaaccttgg
     8701 ttcgttggga aagatgttgc agacatccta ggatatagca aggctagaaa tgcgattgct
     8761 cttcatgttg atgaagatga cgccctaaaa cagggcctca cagataattt aggaagggtt
     8821 caagaaacta tcatcatcaa cgaatctggc ctctactctc ttatcttatc cagcaagttg
     8881 cctcaggcta aagagtttaa gcgctgggtg acatcagagg ttttgccagc tattcgcaag
     8941 cagggcggtt tcattcgcga ggacttggac gaggatgcct ttatcgctct gtttactggc
     9001 cagaagaaat tacgtgagca acaggcgacc atgctggaag atattgacta tctcaagagt
     9061 gagcaaccga ttcacccaag ctatgctaaa tcgctcctga agaagcgtaa ggctcgggtc
     9121 gtggtttgct taggtggcat tgatagtccg gcttatgcgg ataagacttt cgctcagtca
     9181 gtctttagac aagctgagat tgactttaaa gaccacttca acattaatcg ctatgacttg
     9241 ctaccgaaaa aattcgcaga tgcagccttg gcctattgga tgacttggga gccaagcacc
     9301 aataccaaga tgaaaatcat gaaattgaac tcatttgacg aagggtagga ggggaagaag
     9361 atggacaatg ttctactttc actgtctgaa tggattaaat ccattatcaa ggacacaatc
     9421 acaaggctag tcgaaataga aaaagatagt gaccactatc cagagctgat ggatgtgaac
     9481 actacctgtg attttctagg aattaagtat gccacctttt cagataatta tcgttactta
     9541 aagggatttc caaaggaatt acctggtaag aaatggtcaa aaagagccat caaagaatgg
     9601 ctctctaatc aaatataata actttactaa aaggcttctg gacaaggtct tagcaaaatt
     9661 atttgactat attatagcac aaaaagagga taaggagata aaaatgtttg aaccaccgat
     9721 tttagaccag ctgatggggg ttggagcctt actgcttgga tttgcagggg cttgccgtca
     9781 tatcaaattg caggaacaac gcaaggaaga agaaagacga gaagagcaag aatttgcgtc
     9841 tatgattatc caagtgcgta atcatgcata tgaacgtggt agagaggaca aatggcaaga
     9901 aattcgcaag aatattcgca gagagttcaa aggattcaca tatgacaacg aaccgcctgt
     9961 aggcttgcgt cctgagccgt tagctttgcc agaacctaaa cagtctgcaa tcagattttt
    10021 gtaatgagga ggtcaggaaa tgcaagaatt gattgaatcg ctggataacc tgattatgat
    10081 tgttaaagaa ctggaaggaa gggaatcaac ttcaagacat tttattacga tatgggaaaa
    10141 cgattataaa aatctattac gagtcaaaga atacctaacc gactatgaaa aactagcaaa
    10201 ggactatcgt tatatgaccc ttaaaaataa gctgctaaag attgaaaaaa tggagctgga
    10261 aggcaggtac atctatgaag atatgcggat gaagtatcgt gccaatcgca ggaagtgggg
    10321 tgctcggtat gtctgaaatc aagtggataa aaatcaaaac ggatattttt gacgatgaaa
    10381 agatgtgtct aattgatgcc tcgcctgatc gtgatgcaat tattgtaatc tggatcaaac
    10441 ttataacact agcaggcaaa ttgaatacaa aaggcgtact aaccatttct aaaaacattg
    10501 tatacaccga tgaaatgctt gcacaaacgt tccaccgtcc gttgaataca gttcgtatgg
    10561 ctcttgaagt ttttgaaaag tttggaatgg ttgaaaaaat cgatggagtg ataatgttac
    10621 ccaattggga gaaacatcag aacattgacg gcatggaaaa aataaaagag caaaatcgaa
    10681 atagagcagc acgtcaccga caaaaacaga aattacttgc acagaacaac gaaagtaacg
    10741 ttactgataa cgttatggat aacgttacag taacgcatgg taacgcacta gataaagaat
    10801 tagataaaga tatagagata aataataata aggtgatgat tagttccagc ctttctgaaa
    10861 atttgaaaaa tagcggaatc catctaactg ataagtcaca tcaacagtta cttgattatg
    10921 tgggacttga tggaatgagt ttcgatatgt tgaaccgtgc agtcgagaaa acttccggat
    10981 cacacaaacc tagtttcaat tacctaatag ccattcttga aagttggaaa aagaaaggct
    11041 tcacatcgat tgagcaggtg gatgaggacg accgtaaata taaagagggt aagaagtcaa
    11101 gacaacaaaa cgataaaaca tcggaacagg aggtaaggga cgaatgggga ttttagaact
    11161 aattgagcag ttcgagattg actattatcc gttaagctac gagaagaaaa ctcttttagc
    11221 agaccaacca attcatccag tggttgcctg cttgtctgaa atggctagct ggcatgaatg
    11281 cggaggtcgg ctagtatggt agacaatgtg tttgaggaaa tcgccttatc ttatcgtagg
    11341 aatacagaac aacaagaaga gttctgcgaa aagcataaca tccctttgat aaagatattg
    11401 aggaccgaga gtgttgtatg tcgcatgtgt gaatctgagc ggattcatga agaaaatcag
    11461 gaaagagtga atgaactggc taatgctgag aatgagcgag agaggaaata ctatcttgaa
    11521 aagttctctc tttatgatga aattttgaaa aatgctactt tggacaattt tgaaacacca
    11581 accgaaaaag aagcggaaaa gctagctttt gcaaagagga tttgtcgtga gtggtctgag
    11641 ggtgctagga acaacattgt acttcaggga gaagctggaa ctggtaagag tcatttggct
    11701 tttgctatgg ttaaggctct atctgagtac acgaaagaga ttgctatttt tattaacgta
    11761 actgacttgc tgatgaagat taaagctgat tttagtcagg aagagtttct ggtcaataaa
    11821 attgctagtg ctaagttctt ggttttggat gatttaggaa tggaaaaaga tagcgaatgg
    11881 tcatttacta ttctctacaa tatcttgaat aagcgttcaa acacaatcat taccacaaat
    11941 ttgatttctg ccgatattca aaaaagatat ggcagacctt tcatgtccag actaatgaag
    12001 ggtgtagata aagaccattt gatggttttc aatgatttga caaacaagcg aaagcaatat
    12061 ttttagaata ggggtggctg atgtttattt taaagcatgg gacaagagag gataagccgt
    12121 ttctaaggtc tgcaattatc agtgtgactg gcttggatat ttcgtgttct gaggagaaga
    12181 aagccatgcg gtttatttct cgggcggcag ccttacaggt tagcaaggca ttgagaggtt
    12241 cctttgggaa cttctaccct gtcgaggtgg agtgatgtta gagctttatt tcgtctacaa
    12301 cgggcactgt aagtttttcc ttgggaggtt tgacaatgtc gatgatctca ttgagcagat
    12361 ggaagaccat cagtgggctt tctcagctat cactcatcca aggtttcaga agcacattgg
    12421 tcagcggacg acacgatttg actacggttc taaggattgt tactatttag cgactttttc
    12481 aggaggagaa aaaaatgatt gaacttatta aagaatttgg aatggctatt ctgtggttat
    12541 ttcttggcta tttagtcggg gaacgtgcag caagaaagga aaagaaagat gatcaataac
    12601 gttacatttt tagtgggagg taagaaacat ggttggagta acctatcagg aaattcatct
    12661 ctttgttgaa tttttgaaag agcagtacgg gcaaggtcgt ccagactata ttgaagccct
    12721 gaacgactta gacggtctgg tggaagtctc ctacagagaa gctattgaaa gatttttaga
    12781 agatgaagta cgataaacag gctgagattg acggactgaa acgcacgatc gagcaaaacg
    12841 aagagaagat aatcgagtat tcgaagccgt gcgatgcacg caagagacgg attagagcgc
    12901 tggagcgcga tttgttgagg aaaaagaata aagaattaag acggaaagcg gaggagttgg
    12961 aatatgatgg aagagttaaa gcaaaaagtt aatgaagtat acaactggac ggtagaagac
    13021 gggaagccgc aacctcccaa gcaagattta ccacaagcgg tgaaagaccg ggcggactat
    13081 ttttgggaaa tggcagaaga tggtatgacg tttatgggag cgatggaatg catcttcgct
    13141 gatgaaaagc ctacagacta tgatttggga gctactaagg gttggttgcc aaaatctaag
    13201 gagtttgatg attgggttgg ctattcgcca agcatgtctc agttagttat tgcagtttat
    13261 ttgatttaca gaggaagcga agatgaaact taatgaattg attaagaaat ataaaaaact
    13321 tgagggtgta tggaatgctg aaggagcaga actagttcgt caaatttttc tgcaagactt
    13381 ggaacaacta gataaaccgc aaccagtcaa agttccgcag tgtgtggcgg aatatataga
    13441 atttaaaaag aaaaacaatt ttcatgttta cggtcttgct tggcttaacg gctacgaggt
    13501 cgaaaaagag aagcggtatt ttgttaagat taaagggaat attaaagaaa atatgttggt
    13561 ttatggagaa cttttgaaaa ggtatttctt tacaaaaagc tttagtttag acgatgttat
    13621 atattcccac actcgtaaag aactagaagc cgcaaacttc ggctgggtgt ttgattgccc
    13681 aggtattgag attgaggagg tggaataatg ggagatatac gaatactaga cgcttgttgt
    13741 ggcagtcgta tgttttggtt tgataaaaat gagagtcata caactttcat ggacatcaga
    13801 caagaaaaat ttgaaataca tggaaaaagg taaacgtaaa ccctgacgtt gtcggagatt
    13861 ttcgtgatat gccattcgat ggtgaaacat ttaatctagt agtatttgat ccgccacatt
    13921 tgaaatgggc aggtcaaaac tcaattatgc gatcacaata tggccagctg gataaagtta
    13981 cctggtcgga agatttagcc aagggttttg aagaatgtat gagagttcta aaagttggag
    14041 gtactctagt ttttaaatgg tctgattgtc aaatcaacgt taaagaagtt cttaaatctg
    14101 taccttttaa accattgttt ggacaacaaa gaggtactac gcattggatg acgtttatga
    14161 aatttgagaa ggtcacagag agaaaggacg gcacgtttgt aaaagaggag gatttggcat
    14221 gataccgaaa tttagagtgt ggcatcatga attaggtaga ctgatgtcag tcaaatgtat
    14281 gttttttcag gatagcgaga ttgaagaatt tgagttaaac gatgctttaa tgaatgatta
    14341 cattacagct tatcctgatg aaatcgaact catgcaatca acaggactca aagacaagaa
    14401 cggcaaggag gtattcatcg gtgacatcgt taaatgtaca agaggatgtc tccatgaagt
    14461 atatttagaa aaagaatacg gtggtacatt cataggtgga atgcctgctg tatacctaaa
    14521 aggacttgga gatggatatg cgtggacgga atatgaggaa atcatcggca acatctacga
    14581 aaatccagag cttttggagg ataaataatg aacccagaaa taattgacaa tataaacaaa
    14641 ccaagccact accaaggtgc aaacggtctt gaggctatcg atgttgtgca taacttcgtt
    14701 gggagccttt ccggagcgtc tgctttcttt tggggcaacg caatcaagta tatgttacgg
    14761 tttcaaaaga aaaatggtct ggaagacctg aagaaagcta gaaagaatct tgactggctg
    14821 attgaggaga tggagcatga gtgaatacgc attgtatgaa ggcgacacct ttattaccat
    14881 ggggacgctt gcggaaatca gcaaagaaac aggaattgct gaacggtgca agtatttcag
    14941 agtttgccat cgaagatatc tgtacgtttt ttgggattga gatccaagaa aggaaataaa
    15001 agtcaatgaa caaaagaatt aagaagaaga tagctaaacg gcagatacaa gaaaagcaag
    15061 aagaattata caaacaacta cggaaattaa gttctgaaga aattgaagct ataactaaaa
    15121 tgattaatca ggcagtttct aatattcgca aggctttctc tcagatattt gataacttgt
    15181 ttacattttt gaaaaacttg gaggtggaaa ttgaaaaaat tgagcgacga agaactcaaa
    15241 acgttagaca gagaactttt caaatttcaa aacattcaac gcacaataga cttaagaagg
    15301 ctagaattag aaaccagaaa cccagatgct caaagtgggc caactgtagg aataagcaaa
    15361 cctaccgaaa ctatcgcaat cagaatcgca gatgatccga ctttaaaatt tcttgaagga
    15421 tttaaaggga ttattaacaa actcttaagc aatctagtcg aggaggacaa agaaattttc
    15481 aatctacgct ggagataccc tcaactgaga tgggaagaaa tagcagaaca gaaattcatg
    15541 agcaaagcta caatctatcg acgtagaagg attatcttag aacagtacgc tataatgaaa
    15601 ggtgagttgt aaataagatt gagacaaaag acatcttgaa gtctcacaaa aaaagggcta
    15661 ttatgatagc atgaacttct gaaaacaaaa acacaaatca catgttggag ttatcctatt
    15721 tttacagaaa agttgtttaa cagaggaaca tcatgagtca gcaaccagct ggctttttgt
    15781 tttgtagaaa ggaggcagtt atggaatttg tatcaccgat aaaagacaat gataatattc
    15841 aagctatgaa agattatctc agagaatgga atgagatgta ttatatgcta ttcatcacag
    15901 gcctgaatac tggcttacga gtcggagata tacttacctt gaaagttaaa gatgttcaag
    15961 gttggcacat caaactgaga gaacggaaga ctggcaagca gataacaaga cggatgacaa
    16021 aagaactcaa gaaagaaatg aggagatatg ttgaaggcaa accatttcat catttcttat
    16081 tcaagagtag gcaaggtcag aataaagcga tcactcgtga gcgagcctat caaatcatac
    16141 atgaagcagc tgaagaactt ggcattgata atgttggcac acatacaatg cgcaagacat
    16201 tcggctataa atattacaac aagacaaagg acgtaggaac attacagaaa atgttcaatc
    16261 actcatcacc tgcaatcacc ctgagataca tagggataga gcaagcagag cttgatgacg
    16321 cactacggaa ctttgtcatt taatttttta gatattactt tcacataatg agttaagcat
    16381 aaactgaaaa aatgaaagtc ttcaaaacct atgattagta agggtttgag atttagagtg
    16441 agtttaacaa aatataagat atgtgaaagt gagggataaa attggtatag ttacaagagg
    16501 tgaaaaatgg taaaagaata ccgtgatgat tttcttggag aaaaggcctt cgagaaatta
    16561 aataaagata ttgatgccaa tcctgaagtt ggctttgaaa ttgttggata tactcaaaca
    16621 gcatttgtaa atggaatgca tataccgtta acagccatac tagtaaaatg gaataatttt
    16681 tttaaagaat cagaatgaga caaaagacat cttgaagtct cacaaaaaaa ggtttattat
    16741 ggtagcatag atttcttgta tgaggagggg ataggtcaaa ggcctatccc ttttagcatt
    16801 gagaaaggag gtttgagatg tataacaaac ctatcagacc atccttgaaa tctaagaagt
    16861 gggagaagtt ccgtgatagg ataatgcgta agcatgatta tctttgccaa gaaagtttgc
    16921 gttacggaat ttctgttcaa gcagaaatgg tacatcatat ctttcctgtg tctgaatatc
    16981 ctgagcttga atttgttgaa tggaattgct tgccattgac gaataagaaa cataatacgt
    17041 ttcatgatag agtgaacgat agagtaatca accaaggatt gtattggcag aaaaaaagaa
    17101 aaaaagaatt tttaaatttt ttcaaaaatg aaaaatgaaa atttttaatc cccccctctt
    17161 tttgaaaaat cattttggcc agtagggtac tggtgaaggg aactttttcc aagtcggggg
    17221 ccttcaaaca aaaagggggt aaaaactaag cgattttgac gaaaggaggt agtttttggc
    17281 taaaccaatt acagcaaagt cgattaagtc aaaagtggtc aagcagatga aagacttggg
    17341 aacttatcgt aaagagttcg aaatgatcat tgacattttt gcaggtatgt tataccagta
    17401 tcagaaactt gctcaagatt atgctgatat gggttatcca gtaacagaca cctacgtcaa
    17461 taaggctggt gctgaaaatg agcgcaaagt tccaatcttg acagcgatgg aaattttgag
    17521 gaaagatata ctcagctact ctaatcagtt gatgatgaat cctaagtcgc tcggtgaggt
    17581 agtagaacaa gagggtgagt cagttcttac tgaggtactg aagttcaaga acgaaatcaa
    17641 gaagaagcga gtgactggca atgggtaatc ttgataaagc taaaaaatac gctcaacacg
    17701 tcttaactca ccgagaagaa cattgcgaag aaaacatcct tgctgctgaa cgttttttcc
    17761 gtgatttaga aaatccaacc tttgagatgg atgaggatat ggtggatttt gttattcact
    17821 ttatcgagaa cgtgatagtt catcagcagg gcgatgatat gtttgcggta tctatccgta
    17881 acaagccatt gcttttgcaa ccgtggcaac atttcgttgt agttaatctg tttggttttt
    17941 actacaaggg tacgaatgag cgcaggttca aagaagcgct tatcatgctt gctcggaaga
    18001 atgggaagac ctcgtttact gctgcaatcg cacttgctta tcagatatta gatacagata
    18061 gcggttccaa atgctatatc gttgctaact cagtcaagca agcgatggaa gcttttggtt
    18121 ttttaagatt caacgttgaa cgctggaacg ataagaacat tcgtatcaag gataataacc
    18181 aagaacactc tatcaccgcc aattttggtg atgaaggttc tttctttatc caggctttag
    18241 cgaatgatga gagccgtctg gactctttga acggaaatgt tatcatcttg gacgaagctc
    18301 acacaatgag gaacagtaag aaacatggtc ttatgaaaaa aacaatgtca gcatacagaa
    18361 acagtatgct ttttgttatc tcaacggctg gggatattcc taccgggttc cttgctaacc
    18421 gtctgaaata ctgtcaaaag gtgctcaagc aattagtcac tgatgattca tttttcatct
    18481 tcatctgcaa ggctaatcaa tctgctgatg gggacgtggt gaactatctg gacgagaata
    18541 tcctcaagat ggctaatccg tcatggggtg tcacggtttc gctcaaggct ctcaaggaag
    18601 aagcagagca ggctatgaat gatcctcaga caagaaatga gtttttcaat aagaccttga
    18661 atatcttcac taactctatg aacgcttatt ttaatcctga tgagtttatt gcgtcggata
    18721 gttgctacga ttggagttta gaagagctgg cacgtttgcc tattcgttgg tatggtggtg
    18781 cggacttgtc aagattgcac gacttaacag ctgctgctct ctatggtgtc tatcatgacg
    18841 gtgagaaaga cgttgatatc tgtatcacac atgctttctt ccctcggatt aatgctcaga
    18901 aaaaagctaa tgatgacggg attccactct ttgggtggca gtctgacggt tggttgacga
    18961 tgagcaacac tccgaccgtc ctctatgatg atatcgtcaa atggttcatc aagatgaggg
    19021 agaaagggtt caagattgct gctgtcggaa tggataggaa gtttggccgt gagttcttga
    19081 cgaagatgaa acaagctcgg ttcaagatga ttgaccaacc tcagcttttt tatctgaaat
    19141 cagagggatt cagacggatt gagtttaaag ttaagaataa agaattttac tatcttcatt
    19201 ctgatgctta cgaatactgt gtgagcaatg ttagagcaat tgaaaaggtg gacgatgctg
    19261 tgcaatatga gaaattagat ggagacggtg ggactgcaag gattgacttg tttgatgcca
    19321 gcgtctttgc ttgtatacag gctcttgcta atcttggcaa gggtggtgat gtgatgagat
    19381 tctttgatta ggtgaattat gaatgaaata gtattatcag aacatgaaat taacttgctg
    19441 atcaacaaag ggcgagttaa agtaatttta aacggggaag tagtaactat tcgtcaaaga
    19501 catatgaaaa atttgatggc tgaaacagta aaatgggaaa aacaggtaat tgatgtcagt
    19561 cagaatatcg taagaaataa acactttgat tcactttttc aaaatacttt tcgttagaaa
    19621 ggaggtgagg aaacatgggt atttttgaaa agttttggaa acgaaacaag ccaagtaagt
    19681 caatcaacat gctgagtcat tcagatttag ggttgtcaaa cctgatggac tcgtatgtac
    19741 ctttggccag aaatccagat gtggtgacag cggttaataa gattgctgat ttggtctcta
    19801 atatgaccat ccacttgatg gagaatacag ataaaggtga tatcagaatc cgtgatgggc
    19861 ttgctagaaa gattgatatc aatccgtgta aacacatgac aaggaagtca tggattttca
    19921 agattgtgcg cgatttgctt ttatatggcg atgggaactc tgtcctacat gtggaatatg
    19981 aacctgttac ggattatatt tctaatctaa gaccatttcc gatgagagag gtttcattcc
    20041 aaacagataa ggattcctat gtaatctcat ttaggggtga agaatattcc cctgatgaag
    20101 tagtccactt cgtcatcaat ccagatccag atattccata cattggtact ggttttaggg
    20161 tgacgttgac agatgtggtt caaagtttga acatggctac caagactaaa aaaagcttta
    20221 tgaacgggaa gaatattcct agtcttatcg ttaaagtaga ctcgtctagt gctgaactag
    20281 attcggagca agggcgtgag cgtatcgctg agaagtattt gagtactagc agggttggcg
    20341 ctccatggat tgttccagag gcattgctgg acattcagca ggtaaaaccg cttagtctaa
    20401 cggacatcgc tttaaacgag tctgtggaat tggataaaag aacagttgca ggtctattag
    20461 gagtacctgc ttttattttg ggtgtaggag agttcaacaa gacagagtat aacaactttg
    20521 taaatacgac tgtcatgagt attgctacca ctattactca aacactaacc agggacttac
    20581 ttttgtctag caatcgttac ttcaagctaa atcctcgttc actcttctct tacaacatta
    20641 cggagttgtc tgctgttgct caacaaatgg caaacagtgc tgcaatgcgt cgtaatgagt
    20701 ggagggattg gctagggatg gctcctgatc ctgagatgga agagttgatt gttcttgaaa
    20761 actttctccc tcaggagaaa ctaggagatc aaaataaact gaagggaggt gaggaagaga
    20821 atgcaaaagc gaaatagcta tcgtgccact caatttcaaa cgagagaaga agaatctggt
    20881 gatttgattt tgagtggcta ctttatcaag tttgacgagg agacggaatt gtggccaggc
    20941 tactgtgaag ttatcaagcg tgctggtgtt gagaaagctg tcacagacgc tgatatcaga
    21001 gctttattta accatgatga tagccttgtt ctcggtcgaa caggtaacgg aactctgaca
    21061 ctgggtgttg atgatgttgg tctttttgga gatatcatca ttaacaagga tgatcctcaa
    21121 gctgttgggg cctatgcccg tgtcaagcgt ggagatgtta tagggtgtag ctttggcttt
    21181 atcccggtaa aaatcgaaac ggaagaacgt gaagatggtt catatttgga cactgtctta
    21241 gagctagaaa tctttgaagt gagtccatgt actttcccag cctatccaca aacggaaatt
    21301 gctgcacgac aaaaagactt cgaaagtcag aagcgtgcta atcgtgaagc gctagacaag
    21361 cgcaagaaag aaattaagga gaaatttaat ctatgaacaa attattgatt ttgggcgctc
    21421 gtatgcgcaa caaagcagac aaagttgtag agcttgaaga atcaatcaaa gaattgaaca
    21481 agcgttctga acttgaagct aagaaattgg aacaagctgg aactgacgaa gaagtttcag
    21541 cagttgaaaa gaaccttgaa gacatccaaa aagaatcgga tgaaaaggaa gcagaaaaag
    21601 aacaacttga aaaagaaatc gaagatttga aaaatcaagt tgaagaacta aatcgtaaag
    21661 caccgactta cccaagtcaa gaaaaacgtg gaggacagaa attggaacga cgtgacgcaa
    21721 tcgctaaata cattcgtact ggtcaaactc gtgacattgt aggcttgaaa actactgatt
    21781 caggaagcgc agctttaatc cctactgaag ttttgaaacc tcattttgtt aataaaacac
    21841 gtaatccact tttggatctt gtggaacgtg tgaaagttaa tagtggatct ggtaaatatc
    21901 cagttatcaa gaaaacggat ggtgtaatgg tttcaataga tgaattgaaa tcaaatccag
    21961 aactcggaaa accagcaatc agcgagattg attattcaat caagacttac cgtggatatg
    22021 tccctgtgtc acaagaaatg attgacgacg cagactatga catcatgtcc attgttgaag
    22081 acgaagtgtt caatcaaggt gacaacactg aattgtcatt agttacagct gtcctcaaaa
    22141 cagctaccca agcagatgcg gctggatttg atggtattaa agatatctac aacaagaagc
    22201 ttaaatcaat ttataaagca agcatcgttg taactaagtc aatgtttgct gcgcttgaca
    22261 aagtgaagga caaagatggg cgctacatgc ttcaaactga tgtggcttca cctactggct
    22321 attcatttgg tgggaaaaca atctacaaag tagatgacac agtgtttgga aacgaaggag
    22381 atatgaaatt cttcatcgga gatgttactg agttcgtcaa agagtttgac cgttctcaag
    22441 tatccgttaa atgggtgaac aatgacattt acggacaatt gcttgggctt tttatccgtt
    22501 tggatattaa gaaagcagat gaagaagctg gattcttcgg aacatatact gatgttgtag
    22561 cttaaggagg tagcgtatga gctataaagt aatccgtcct ttcaaggact tggctgatcc
    22621 tgaaaatcat gactacgctg ttggcgatat ctttcctcgt gagggatatg agccaacaga
    22681 tagctttacc aatggccttt tgactggcgc taacactgct ggctctatct tccttgaggt
    22741 tttgggagat gatgaaccta agaaaccagc gcctgaaaca aaagaagtga aggaagagcc
    22801 cgcagttgag caggaagaaa cagttgagga aactgctgaa gagtctgctg aggaagttga
    22861 ggaatagaca tggaccaagg tcagctttta gagttgctga agcttaagtt gggtatttca
    22921 accgacttga gagacaagcc gttaaaaaaa atcatttcaa gtgtcatcac tgaattgacc
    22981 gataatctcg gtatcgagct tgttggtgag cgtgctgacc atgaaatgtt tatcgttgac
    23041 tatgccgctt atcgttatga gggtggggtg gatatgccac gtcaccttca gtggcgactg
    23101 cataatttac agatagcatc aaagaaagag gtcaagaatg tggaatcatg aaatcacact
    23161 gatctccaag aaagtaacag gtaaggataa gttactacaa ccaatctctg aagatgttga
    23221 agttactctc ttatgtcgca aaaagagggt cactcgctct gaattttatc aggcgaatca
    23281 ggtagggctt aaaccgagct tggtcgttga gattcgaaat tttgagtatg agaatcaaga
    23341 gcttgcgaag ttcgaaggca agcaatatca tatcttgaaa acctatccta ttgattctga
    23401 aattttagag ttgactttgt cagaggtgtt gaaatgagta atgaccttgc tgatttgata
    23461 gcgaaagagc ttgcagctta ctctgatgag gttactgaag aagtggataa gattgcagag
    23521 caagtgactg atgagactgt ggatgagttg aaagagacaa gtccgaaacg gtacggaaag
    23581 tatcgtagaa gttggaaaaa gaagaagttg gccaatggct cttttgttgt gttcaacgca
    23641 gttgcaagtc ttactcacat acttgaaaac gggcaccttt caagaaatgg tggtcgtgtc
    23701 gctggtatcg tccacatcaa gccagctgaa gaaaaagcaa ttcagaactt tgagaagcga
    23761 atcaaggaga ttgggaaatg aagctatcag actttgctgc tattttggaa caggcaaact
    23821 tgcctgtcac ttatcgagcg tttaaaattg gaaacgctcc tgacctacct tatctggtct
    23881 attatgaatc aagtccagtc atcaattcag ctgacaacac ggttaatcat cagattaaga
    23941 gcgtgacagt tgagctggct tttgagagta aggatgaaga tttggaagaa cgtctggaag
    24001 agctgtgggc aaaccacaag ctcttttttg aagttcaaga agaaacattt atcgagactg
    24061 aaagactcta tgtcaagtct tacacagtct atctatacta aggaggaatg acatgactca
    24121 agaaaataaa gtaacctttg gcctagaaaa tgtacatatc gcacctatca agacacttgc
    24181 agcagatgga gttatcactt acggcgatgt ttttcgtttt cctggagcaa tagagctgat
    24241 acttgatact aaaggggaaa caacccctat caaagcagac aacaaggatt accatttcat
    24301 gaattcaaac gaaggatatg agggtaaact taaaatccca cacatcattg atgaatttgc
    24361 gacaaaaatt cttggtgaaa tcaaggaccc tcaaactggt gttatgactg aaaaagcaga
    24421 tgcgagcttg acagagttcg caatgatgtt ccagtttgaa ggcgacaaaa acaagactcg
    24481 ctatgtgatg tactactgtt ttgccagtcg cccatctctt ggctcaaaaa ctaagaacgg
    24541 gacatcaacc aacgaacgtg aacttagttt caaagctagc ccgcgtccat tggatacagt
    24601 tgtcaagcgt tctatcacat cagctgatga caaggatgcg tatgacaact ggttcaagaa
    24661 agtgtatgaa cctactgcag ttgcagctta aggagaagat ctatgcgtaa aatcgttttg
    24721 gttggtgatc aggagtatga gttggggacc aacggctata ctcctattgc ttacaagcaa
    24781 caatttggaa aagattattt tcaagatttg ttctcgatgt tgaaaaatca atcattcatg
    24841 aatgaattga acaagttgga aaccgacaag gaattgacag cgactaatat tgatatttcg
    24901 atgttgtcag attttgacat gacctttttc aaccgtcttt tttggacctt tgctaaatct
    24961 gcaaatcctc acatcaagcc ttatgaacaa ttcttcatgg aaatggaaat cttcccgatt
    25021 caggaagttg gacctgtgct gatggaaatg ctaaatgcga gcatgacgac aaaaaagcac
    25081 cagatgagtc agaatcagct agcgaagaaa tcttcacagt agaatcctat ctatcttgct
    25141 gtaaagaaac tggtctttct attgatgatc taaagcacat ttcaatcgga atggctctgg
    25201 attatcagac ggattatgtg aatctacgga gcgaggataa gggtggcgaa cggaaagcca
    25261 cgcaagctga ttttgacagt ttttaaagaa aaatgagtgc tgagagagcg attctgagac
    25321 caagttcctt ggtctggctg cattatcagt ggtagaagtt ctctcagcgc ttttctattt
    25381 ttttgagaaa ggaggaaata tggcaggaaa tatcaaaggt atcaaaattg aaatcgatgg
    25441 cgacacgcaa cccttgcaga aggcgctgaa aaatgtcaat aaggccgcta ctgatgcaag
    25501 tcaggagttg agacagattg acaaggcctt gaaatttgat acagggaacg taacgctcct
    25561 gactcagaaa caagaggtct tacaaaagca agtttcgacg accaaggaga aactggaaac
    25621 cttgagacaa gctcagtctc aggtggaaca gcagttcaaa aatggtgata tcggtgctga
    25681 tcagtaccgt gcctttcaac gcgaagtcga agttactcaa aacgtcctaa aaggatatga
    25741 gggtaagctt gcaaatgtga atcaggcgct taatgagaat gggagtgcta ctcagaacaa
    25801 caagaaccaa ttaaaagagt tgcaaaatga gcagagtcaa cttgcttcag agatgagtaa
    25861 ggtgacaagt tcattcaaac tgcaagaaag cgctttgggt tcaaatgcta gtgaagccga
    25921 gagaaatgct cttgcccaga aaaagattgg tgcccagtct gagattgtaa gtaaacagat
    25981 ttcaaatcta gaacagcaat tggaaatcac taaaaaagaa tttggtgaga actccacaca
    26041 agccaacaag atggaatctg agctaaatca ggctaagact gcttttaatc atctcaatga
    26101 tgagatgaag ggaacaaagt ctgctgctga tagcactcaa gaaagtttaa gtgaaatctc
    26161 aagaaattta agagcagaac tacttcaaca gtttagtgag aagttgagtg ctatttcaga
    26221 aaagcttgtg gaagtaggaa aagaagcgtt agaagcagct gctcaaatgc aagctagtaa
    26281 tgctcaattt actaccgttt tcggagatat ggaaacccaa gcaagagaag cgttgaatgc
    26341 tattggtcag gaaatggata ttgtcccaga gcgtttacaa gggtcattta ctcagatggc
    26401 ttcatttgct aaaacttcag gactagacac tgcgcaagca ttggacctga cttcccgtgc
    26461 aactagggca gcggcggatg gcgcagcttt ttacgacaag tccatcgaga gcgtatcaga
    26521 aagcctacaa tctttcctga aaggaaactt tgctaacgat gccgctcttg gaatctctgc
    26581 gacagaaacg accaggaatg cagctgcaaa taaattgtac ggaaagtcat tcaaggactt
    26641 gagcgaagcg cagaagcaat tgaccttgct tcagatggtc gaagacggaa ataaactctc
    26701 aggagctctt ggacaggctg caagagaatc agacggccta gaaaacgtga tggggaatct
    26761 gaaacaagct gggaccaatg cattatctgc tattggtcaa cctcttctag aaatgatgat
    26821 tcctgttttt caaaccttgg caacgattgt gaaaggtgtg gccgagctgt tcaattcctt
    26881 gcctgatcca gtaaaagatt ttgttgttat tttaggaaca gttgtgactg ctgtaggggt
    26941 catagccccc atattcttaa ccttgcaagc ccttgctgag tttttaaaaa tatctattgg
    27001 agaaatgata attgccgcat tgccaattat tggaacagct attgcaattg ctgctgcagt
    27061 tgctgcaatt attgttattg taaaatatct ctgggaaact aacgaaggtt ttcgagatgc
    27121 ggtcacgacc gtttggaatg ctatactagc cgttatcaat acagttgttt cagaaatctc
    27181 tgatttcatc atgagtatat tcgggacggt tgttacttgg tggacggaga accaggaact
    27241 tatcaggaca agtgctgaga ctgtctggaa tgccatttat acggtcatca gtacaatact
    27301 ggatatactt ggccccttgc tccaagctgg ctgggataac attcaactga tcattacaac
    27361 aacttgggaa atcatcaaga tcgttgttga gactgcaatc aatgttgtcc ttggtgttat
    27421 ccaagcagtt atgcagatca ttactggtga ttggtcagga gcttgggaaa ctatcaaggg
    27481 agtgttttct actgtatggc aagctattca aagcattgtt cagactattt tctcagctat
    27541 ccagagttat atttcaaata ttctcaacgg catttcagga actgtatcaa atatctggaa
    27601 cagcatcaag gacactgtct caaatgtgtt aaatgctata tctagtactg tatcaagtgt
    27661 ttgggaaggt atcaagagta ccatttcaag tgctatcaat ggtgcaaggg atgctgtttc
    27721 ttcagctatt gaagccatca aaggattgtt taacttcaac atcagctggc cacatatccc
    27781 actacctcac ttttacgtga gtggttcggc caatccatta gattggttga gtcaaggtgt
    27841 tccaagtatt ggaatcgaat ggtatgccaa aggcggtatc atgacgaaac caactatctt
    27901 tggaatgaat ggtaataaca taatggttgg tggtgaagct gggaatgaag cagtattgcc
    27961 acttaacgac aaaacgcttg gagccatcgg tcgaggtatc gctcaaacta tgggtggaac
    28021 ttcaccaacc atcaacatta ctattactgg taacaccgtc agagaagaag ctgacatcag
    28081 tcggattgct gatgaggtgg ctcagcgtat tgctgacgaa ttacaacgta ggagacaatt
    28141 gagaggaggg tttgcatgat aaagcataat gagcttgtga ttgacggtgt gaggacatcg
    28201 tcttttccat ttaagatcat tgtccatgac tctccttcaa tcgctctagg agagagcaag
    28261 acagctctct tggagcatgg tggtgtcagt ggggcaatcg ttcagacaaa caagcatagg
    28321 gaactggtca agaaaactta tacgatttac ttggtcaaac ctactgaaga acagatgaac
    28381 caatttatga gtctgtttat ccgtgaaaag ttctggctag agagtgagcg agtcaaaaca
    28441 actcgtcttt ggtgctataa ggtcaatgtg agcgaccttg aagaagtgca acctggtctt
    28501 tacatgacca aagcaacctt cacttgccat cctacaaaat actttaaaga ctccgataca
    28561 cagagattga caagaagtgg gactttgacc gttcaaggtt ctgctcttgc ctttcctaaa
    28621 atcacaatcg ttggtcagag cgcttctgaa acttcattta caattgctgg tcaggtcatt
    28681 cgtcttgaac gactcactga gtcgcttgtg atggttaata atcctgacaa tccaagtttt
    28741 aaaacaacaa cagggaagcc agtcaaatgg tcaggggatt ttatcacagt tgatccagcg
    28801 aaagtgaaga atattggggt tgttttaggc ccaggtattc aatcgattga aatcgaaacg
    28861 gtttgggggt gggcataatt gctttatcta cttaataaag atgtaagaac cgttcgatgg
    28921 aacggggagc cacttcatga agcgacttcg gcgattgtga aagaaactat gaatggcgat
    28981 tttaccttga ctgtgaaata tcctatttct gattctggta tttaccagct catccaagaa
    29041 gatatgctga taaaggctcc gactcctgtc ttaggagcgc agctatttcg tatcaagaaa
    29101 cctgttgagc acaatgacca tctggaaatc acagcctatc acatttcaga tgatgtgatg
    29161 caacgatcta tcacacaaat gagtgtgact agtcagagtt gtggcatggc tcttgctcgc
    29221 atggtacaaa acaccaaaac ggctcttgga gacttctcat tcaacagtga tatccaggac
    29281 cgtaggacat tcaacacgac tgagacagaa accctgtact ctgtattgct ggacggcaag
    29341 catagtatcg ccggaacgtg ggaaggcgag ctggtgcgtg ataactttgc gatgactgta
    29401 aagaagagtc gtggtgagaa tcgtggtgtt gttattacaa cacataagaa tctgaaggac
    29461 taccaacgaa ccaaaaacag tcaaaatgtt gttacaagga ttcatgctcg atccacattt
    29521 aagcctgaag gtgctgaaaa ggaaacaact atcagagtga ctgttgatag tcctcttatt
    29581 aattcttatc cttatataaa cgaaaaagag tatgagaaca acaacgcaaa atccgttgaa
    29641 gagttgcaga agtgggcaca gtctaagttc tcaaatgagg gaattgacaa ggtctctgat
    29701 gctatcaaaa ttgaagctta tgaacttgat gggcaagtgg tccatatggg cgacacggtc
    29761 aatctcaaga gctggaaaca taatgtcgat gcattcaaga aagctattgc ttatgagttc
    29821 gatgccttaa aagaagaata catctctctg actttcgatg ataaggcagg tattggtggt
    29881 tctagatctt ctggtggcct atctagcgca gccgatgcaa ttcttggagt gacagaatct
    29941 gcacaagaaa tcgcccttga aaaggctctt caaaatgctg acttagactt tgatcataag
    30001 gctggattgc ttagacagga aatttctgac gatattgaac tggccaaagc cagagctgaa
    30061 gaagtcaaga gagaactgtc tgacactatc aatcagcgat ttaatagctt tgacaacggg
    30121 ccattgaaag aaactaagcg caaggctgag gaagctttgc gaaatgctgg cgcaagtacc
    30181 ctgcttgcac aggaagctaa gcggattggg ctggattctg tcgctagact tgaagcgttt
    30241 aagtcgcaga ctacgagcgc acaaacggct ctgtcgggtg acttggacgc tctgaaacgg
    30301 actatcgcga atgatattcg accgaagcaa gcacaggctg aagctgagat tgccaagcaa
    30361 gctgaagcac ttagccggac taaaaatgaa ctggctggcg caagtaccct acttgcacag
    30421 gaagctaagc ggattgagct ggattctgtt gctagacttg aagcgtttaa gtcgcagact
    30481 acgagcgctc agacggcttt gtcaggtgac ttggatgttc taaaacaaac tatcgcaaac
    30541 gatattcgac cgaagcaagc acaggctgaa gctgagattg ccaagcaagt tgaagcactt
    30601 agccggacta agaatgaact ggctggcgtg aagtcagcgc aagcgacgta taaggagacg
    30661 acgactcgta gactgtcaga actgaccaac ttggcaaatg gtaaagccag caagtcagaa
    30721 cttacgcaaa cagctgagga gctggctagt cggattgcga gtgtgcaggc aggtagttca
    30781 cggaattact tcaggaattc acgttcaaga acgttcacaa caggaggtca agcggtatac
    30841 gactatcgaa cattcatagt tcctgatttc tggaagaaca gtgacaggtt caagcgtgat
    30901 tatgttcgca tatcttttga tgtgactttc cctgtcgccc tagtaaatga catgcctgct
    30961 atggtgcatt ttagtgctca tccatggtat gcctacagaa acttaatttt taaaggtgga
    31021 actgtcgaac gccaacattt tgagtttacg attgacttgt ctagttcttc tgaggactat
    31081 cagactaata atgtgttcat tcgttttggt actaattatg gatttcctgc tggtctgcag
    31141 gtcgtcattg agaacgctat gttatcggtt ggtaattatt ttccagccta tcaaccagcg
    31201 tatgaagacc aagaagaccg tgtctcagta gtcgaatcca actttaaaca gcgtgctgat
    31261 tcactcgacg ctggtgtaag aagcttgact gaaggcctta gaaccaaagc ggatatcagc
    31321 tcactcaatg tgactgctga aaatatccgg caatctgtga agagccttga gacagatacg
    31381 cagaacaagc taaatcagaa gttgagtcag gctgaatttg aggtgcgagc cggctctatc
    31441 cgtcaggaaa tcctgaacgc aaccaaggat aaagccagca agtcagaact cacgcagaca
    31501 gctgaggagc tggctagtcg gattgcgagt gtgcaggcat ccggtcgaaa tctattcttg
    31561 aactcactat tcaagcagga tattccaaaa acaggaattt ggacaacgag tacatatacg
    31621 gctactatcg atagcgaaag taagtatctt ggacacaagg ctcttaaaat tataggtttg
    31681 aatccatctg gccgtgatgg aggtaatccc aaggttactt atccagctct gggtcaattc
    31741 gggaaagtaa ttcccggaag tacgactaat caagatgtaa ccattagttt ttatgctaag
    31801 gcaaataaaa atggaataat gctaagatct cgattaggga atatcggata taaaactgga
    31861 aatgtgacat tgtcgacaga aattaagcga tatgttgtcc atattccaaa aggttggaca
    31921 aacgaatcca agcagaccac aaatgaatgg ttgttcaatt tcaaccagga aggaaccatt
    31981 tggatttgga tgccgaagtt tgaaataagc gatgtagata cttcttattc agaagctcct
    32041 gaagatatag aaggtcagat ttcaacagtt gaatcgacct tcaaacaacg agccaactaa
    32101 ctcgacgctg gtgtaagccg tctgactgaa ggccttagaa ccaaagtgga tatcagctca
    32161 ctcaacgtga ctgctgaaaa tattaggcag tcggtgaaga gtcttgagac agacacgcag
    32221 aacaagctaa atcagaagtt gagtcaggct gaatttgagg tgcgagcaag cggaatccgt
    32281 caggaaatcc tgaatgcaac caaggacaag gctgacaaga ccttggtaac agcggaggct
    32341 gggaagttga gagaggagct gacaagtctg tcggttggcg agaatctgtt tgtaaactca
    32401 gattttaaaa atctgaggga taacggacag cgttatacag ctaacggcaa gacctatcaa
    32461 aacatgattg cgccttactg gtacaatccg tacaatgctg gtattccaaa tgctcaaaat
    32521 atccagcatg ggtattttga cacggaaacg tttagtgata ctgtctttgc ctttaacgag
    32581 agcgacggct cccgacactg gaaagcattg tcaactgatt ttaaaatcgg agtcatctca
    32641 gctggagagt attacttttc agctgatttg tatgcgacag atttaggcac tcatatcaaa
    32701 tttggatttt actatcacaa ctcgactggc aaactcaatt tttacgcagg tcgaacaaaa
    32761 attgaagtta ctgaaaaagg ccgttggact aggctaggaa ttgacttaaa ggtcaatgat
    32821 gacattgacc tgacaaaaaa agtccaattt tacatttacg gctataattt tgctagcaac
    32881 tcaattttgt accttaaaaa gcctaaagtc tcgaaaggtc gcttaaaaag cgattggagc
    32941 ccagctctgg aagacaccga aggcctcatc actgaggcta aggcaacctt tgagcggaca
    33001 gctcagggct tgcgaaccga cttatcagct attcaggaat atgtaaataa agacggtcag
    33061 cgacaggaag ccctacagcg ctatactcgt gaggagagca cgagacaagc gacagcagtc
    33121 cgtgagctgg tcaatcgtga tttcgttggt aaggctactt atcaagaaga tgttaagggt
    33181 atcaatcaga ggattgaagc tgttaaaact agtgcgaata aagacatcgc tagtcaaatc
    33241 gctagctatc gtcaatctgt agatggtaag ttcacggata tttcaagtca gataactact
    33301 tataagcaag atgtgggcgg tcaaatcagt ggtctatcaa atagacttac aagcagtgag
    33361 caaggaacca ctactcagat ttcaaatatt tcaaatcgga taaacagtaa taaacaaggc
    33421 acagataatc agatttcaaa tttaaagact caggtcgcta caaacaagga taatgctgaa
    33481 cgacaaatgg gtagaatatc tgatcaggtt tctgcaaaca aagcgaatgc tgatagtcaa
    33541 tttgcgaatg tgaccaatca actagcgcga aaagtagaga ctactgactt ccagcgtgtt
    33601 aaggaaacca gtaaacttta cgagcggatt ttgggcaata ctgaaaatgg aattgcggat
    33661 aaggttgctc gcatggctct gaccaatcaa ctgtttcagg ttgaggttgg gaaatatagt
    33721 gtaagcggcc ctaacctcat taagaatagt gattttaaaa atggtacgaa tgaatggggc
    33781 tcaactcaaa atttaggaag attggttaag catagctttt atcacaacgg gcagaaagac
    33841 cttatgcgtt taagtaatgc aactaaaaac gaaaactttt tgtatagtca ccgttttaat
    33901 cttgaacgaa atactgacta tgtactgaat tttagaggat ttaacaacag tgctctcgca
    33961 agctatgatg tttatatttt gggacgaaga gcaggcgaga gcgatggatt cacaatcgtt
    34021 aagaaagttg ttagcagcaa gaaactatct acctctagat gcgaagatgt ctcagtaact
    34081 tttaattccg gagaaatgga taatgcttac attcgttttg ataacaatgg ctcatcatca
    34141 ggaacagctg atttgtatat tacagaagtt gacttgtaca aaggttataa acctagaaca
    34201 tggcaaccac atccagaaga tgcagtcgca gatgcgaata agaagcttga agccacgcaa
    34261 acaaaaatga ctcaactagc tggctcatgg gtagttgaaa acatcaactc ggctggagat
    34321 atcatctctg gaatcaatct tggcgccaat ggacataacc gctttgttgg gaaattgacc
    34381 cacatcactg gagagaccct gattgacaga gcagtcatca agtctgccat ggttgataag
    34441 ctcaaaacgg ccaattttga agctggttcg gtcacgacta cgatattaga cgctgaagcg
    34501 gtcacggctg ataaagtgag atttgatgct gcgtttatta gaaaaatgat tgcaaatgac
    34561 gcttttattg accaactgac atctaaacgt atcttctcta ctaaggttga gtccgtcatt
    34621 tctagttcaa ccttcctaga agcctatcaa ggccgaatcg gtggatttac acttggtcaa
    34681 tttgatcagg gtggcggtcg ctggatttca ggtgtcaatc agttctctgt tggtatgggg
    34741 aatggtgccg ggcatggggt gccggacagc cttctgggcg aactggggaa ataattggaa
    34801 ctatgccgga cctaaagcat ggaacgtcaa tactgatggg aaaatgtact gtaggaatga
    34861 agtcggtttt tatgatcaag tggatttttc gaattcatcg agagcaaact tctatgggaa
    34921 tactactttt tctcgttctc ctgtgttttc aaatggtatc gaacttggaa gtaaagatgt
    34981 gcttggtgat ggttggaatc ccaaaggcgg aaggaatgcg gttgtttggt ggaatcaggt
    35041 cggtagcggt agcgtgaagt attggatgga acaaaaatca gacagacgct taaaagagaa
    35101 catcacagat acagctgtga aagccttgga caaaatcaac agattaagaa tggttgcatt
    35161 tgatttcatc gaaaataaga aacacgagga gattggtcta atagctcaag aggctgaaac
    35221 catcgttcca agaattgtct cacgagatcc tgagaatcca gatggctatc tacatatcga
    35281 ctataccgct ttagttcctt acttaatcaa ggctattcaa gaattaaatc aaaaaataga
    35341 aaaaatggag aaaacaatag catgaataac aacatgttga ccaatatcgc acttaaagca
    35401 attcaggagt ttgctcttga aaatagaaaa cgaacacaca gattggagaa cttagaaaat
    35461 gaacacagaa cagcttaacc aagccttaca aatgacaatt cgtgaaatgt caacaacttc
    35521 aacagattcg atgattgcaa gtaatttctt gagtattcag ttgaatgagc aaagggaaga
    35581 gaatcaaaga cttcaagcac gagtggatga gctggaagct ctgcttgatg aacaaactaa
    35641 accagcagac aaaggagaat agacatggca gaaacaattc aaaacacaga taacttacta
    35701 gaccttacaa aaatcacaga accatttgat cttgcgagcg ctttgcgcta catgaaagaa
    35761 aatggagagt tcattcgttg caagaatgta agcgatgact tctatatgta tcgtgatgtt
    35821 caaaaacgtc ctgtgatcgt aaatggccgt cgccaattca aggatgttga aactgtttgg
    35881 gcgttcaacc agtggggggg ggtacaatca caacaatcaa cgtagccgtt ctgttgaatc
    35941 atgaattcta tatcatgaaa tttgatgcag agggcaatcc tgactggacg gatccaacgg
    36001 taaaacctaa agaataggag gtgtgtatgc aaattgaatt tttcaatttt ctaagaagtg
    36061 tcgtacagac tgaagatggt ttggtcttgt acgctctagc actgattgtc tcaatggaaa
    36121 tcattgattt tgtgacaggg acgattgcgg cgattatcaa tcctgacatc gagtacaaga
    36181 gcaaaatcgg cattaacggg ctccttcgta agatttcagg ggttctctta ctgatgatcc
    36241 tcattccggc gtccgttttg ttgcctgaaa agacaggttt tgtattcttg cactcaatct
    36301 atctcgggta catcgcattt acttttcaat ctctcattga aaattaccgc aaattaaaag
    36361 gaaatgttac tctttttcag ccgattgtaa aagtatttca gcgattactt gaaaaagatg
    36421 atgatacgaa aaaaggagaa taacaaatgc aacaaattac tgaaatcatt actaatggag
    36481 caatcagcat cctagtcatt ttggcagggg tggtagttag ggtagtcaag gaatacctcg
    36541 tcaaaaaagg tggagaaaag actatcaaga ttgttgaaat cttggccaag aacgcagtta
    36601 atgccgtgga gcaggtagct gctgaaactg gctacaaggg agatgaaaaa ctggcacagg
    36661 ctcgcgctaa aattcgtgca gagctgacca aatataatat cagtatgacg gacaaggact
    36721 tggacacctt tgtggagtca gccgtgaagc agatgaacga cgcttggaaa ggacaagagt
    36781 aatggatatc gatagaaaca gactacgtac aggcttgccc caggttgggg tgcagcctta
    36841 tcgacaagta catgctcact caacaggcaa ccgtaactca accgctcaaa atgaagctga
    36901 ttaccactat agaaaggacc ctgaactagg gttcttttca catgttgtcg gaaacggccg
    36961 catcatgcag gtaggacctg tgaacaacgg aagttgggat gttgggggcg gttggaatgc
    37021 tgagagttat gcagcggttg aactgattga aagccattca actaaggaag agtttatggc
    37081 tgactatcgc ctctatatcg aattgctacg caatctagca gatgaagcag gtttgccgaa
    37141 aacgcttgat acagggagtt tagctggaat taaaacgcac gagtattgca cgaataacca
    37201 accaaacaac cactcagacc acgttgaccc ttatccatat cttgcaagtt ggggcattag
    37261 ccgtgagcag tttaagcaag acatcgaaaa cggcttgagc gctgcgacag gctggcagaa
    37321 aaatggtact ggctactggt acgtacactc agacggctct tatccaaaag acaagtttga
    37381 gaaaatcaac ggtacctggt attatttcga tggctcaggc tatatgcttt cagaccgctg
    37441 gaagaagcac acagacggta attggtacta ctttgaccaa tcaggcgaaa tggccacagg
    37501 ctggaagaaa atcgctgaga agtggtacta ttttgatgta gaaggtgcca tgaagacagg
    37561 ctgggtcaag tacaaggaca catggtacta cttagacgct aaagaaggcg ccatggtatc
    37621 aaatgccttt atccagtcag cggacggaac aggttggtac tacctcaaac cagacggaac
    37681 actggcagat aagccagact tcacagtaga gccagatggc ttgattacag ttaaataaat
    37741 agaaaggaaa ctttctaaat tgttctttca ccgcaggctc aggcttgcgg tttttttgtt
    37801 tgtctgaatc aagaaagcgt ctaaccaacc gacaccaatg tcggtagcaa aataaatggt
    37861 ttgcctaaaa aattagagtt aagttctatt tttcaaaaac acgcattttg aacgattaga
    37921 aacagaaatc taaatcctat tgttcaaaaa aacgtttaca tgaaaaatag ggaggtgttt
    37981 tgttaaaaat aaaaacagtg atcgaaatca ctgcttatca gttgtagcaa attcataaag
    38041 tttttctgct gtgagaagtg ccattttgtc catgcttgtt tttccttttc tgaggtcaga
    38101 aacagtagtc catggaactc cagcaccttg ggaaatagca gatgtagaca tcgaactgtc
    38161 taacaattct tgaataactt ctctcatctt atttgtcctt tttatttttt agataaatat
    38221 atacattgat tgcaattata aaaatagcta ttgcactaac cattgcattt cctctttcca
    38281 tttgataaaa tagaggtgta aggggctttc gccccaacct cttagcgttt acctttttct
    38341 ttgacgggat ttcggtttac gctttttgtt ttgccttgcg accgttattg cggtcactag
    38401 acttgcgata gcagttaccg tttcaggaat attgtctatt gccttttcaa gtaacctgag
    38461 ccaatcttct ttgttcaact tcatcacccc ctttccttat cttgattata ttatatcacg
    38521 gtacaccgag aaagtcaagc gttttgatga agtttttttt aattttttca aaaaaaaata
    38581 gaccttgtcc agaggtcggg gagttggagg gggcaccctc caaaagcatt gatttaataa
    38641 ggttttattt tacctttttc ataataatct ccctatagag tcaccgcatt cggtggcttt
    38701 ttttgtgttg ggattcatga tataataata aaatcgataa gtaggaaaag agaaaagaga
    38761 tgtattatac gcttgaagaa aaagaagtct ttatgaggga ggctttgaga gaggctgaga
    38821 ttgctcttga acacgatgaa attccaattg gttgtgtgat tgtcaaagat ggggaaatca
    38881 ttggtcgtgg gcataatgcg cgtgaggaat tacagcgagc ggttatgcat gcggaaatta
    38941 tggctataga ggatgcgaac ttgagtgagg agagctggcg cttgctggat tgcacacttt
    39001 ttgtgaccat tgaaccttgt gtcatgtgta gtggagcgat tgggcttgcc cgcattccaa
    39061 atgtggtcta tggggctaaa aaccagaaat ttggcgctgc tgggagtttg tacaatatct
    39121 tgacagatga gcgtctcaat catcgtgtgg aggttgaaat aggaattttg gaagatgaat
    39181 gcgcagctat catgcaggat ttttttagaa atagacggaa aaaataattt tgcttttaaa
    39241 atgaatagga atgtgatata ataaatagtg gagcaacagt tctgcgtgaa gcgggtcagg
    39301 ggaggaatcc agcagcccta agcgatttga attgtgtgct ctttttttcg tgctttttcc
    39361 gaataaataa gatagaataa tctagaataa atgataatag aaaagagaaa attatgaaaa
    39421 ttcgtggttt tgaattggtt tcgagtttta cagatgaaaa tttattgccc aagcgtgaga
    39481 cagcgcatgc ggctggttac gacttaaagg ttgctgtgcg tacagttgtt gcgccaggag
    39541 agattgtctt ggttccgaca ggggttaagg cttatatgca gccgactgag gttctctacc
    39601 tctatgatcg ttcttcaaat cctcgtaaga agggcttggt tttaattaac tcagttgggg
    39661 tcattgatgg ggattattat ggaaatcctg gaaatgaagg gcatattttt gcgcagatga
    39721 agaatatcac agatcaagag gttgttcttg aagttgggga acgtattgtc caggctgttt
    39781 ttgctacttt cttaattgca gatggagatg cagctgatgg cgttcgaact ggtggatttg
    39841 gatcgacagg gcactagaat gaagattatc tttgtacgtc atggggagcc agattaccgt
    39901 gagttagagg agcgttctta tataggattt gggatagatt tggcaccctt gtctgagatg
    39961 ggacggcagc aagtccagaa attgagcaaa aatcctttac tctcgtcagc tgaaataatc
    40021 gtatcttctg cagtcacaag agctttagaa acggcttcgt atgtggtctg tgctacgggt
    40081 cttcctttaa gagtagagcc tttattacat gaatggcagg tctataaaac aggaatagaa
    40141 aactttgaaa cagctagaag actgttttta gaaaacaagg gggagttgct tcctaatagt
    40201 cctattcaat atgagacagc tacggaaatg aagtctcggt ttctagaatg tatgtctaag
    40261 tatcgagaac atcagactgt ggtagttgtt gctcatcgaa tgctcatgcg ccagtttgtg
    40321 ccaaatgaga agattgattt ttgccaagtg attgagtgtg agttagagat atagaaagag
    40381 gtttgtcatc gcaaagaaaa aagcgacatt tgtatgtcaa aattgtgggt ataattcccc
    40441 taaatatctg ggacgttgcc ccaactgtgg gtcttggtct tcttttgtgg aagaggttga
    40501 ggttgccgag gtcaagaatg cgcgtgtgtc cttgacaggt gagaaaacca agcccatgaa
    40561 actagctgag gtgacttcca tcaatgtcaa tcgaaccaag acggagatgg aggaattcaa
    40621 ccgtgtgctt ggaggcggag tggtaccagg aagtctcgtc ctcatcggtg gggatcctgg
    40681 gattgggaaa tcaactcttc tcctacaagt ctcaacccag ttgtcccaag tggggacagt
    40741 tctctatgtc agtggggagg agtctgccca gcagattaaa ttacgtgcag agcgcttagg
    40801 tgatattgat agtgagtttt atctctatgc agagaccaat atgcagagtg ttcgtgcaga
    40861 agtggagcgt atccagccag acttcttcat tattgactct atccagacca ttatgtctcc
    40921 tgagatttca ggggtgcagg ggtctgtttc tcaggtgcgt gaagtgaccg ctgaactcat
    40981 gcagttggcc aagaccaata acattgccat ctttatcgta ggtcatgtga ccaaagaagg
    41041 aaccttggct gggcctcgta tgttggagca tatggtggat acggtgcttt actttgaagg
    41101 ggagcgtcac cacacctttc gtattttgag agcggtcaaa aatcgttttg gttccactaa
    41161 tgagattggg atttttgaga tgcagtcggg cggcttggtt gaggtactca atccgagtca
    41221 agttttccta gaagagcgtt tggatggggc gactggttcc tccatcgttg taaccatgga
    41281 agggacgcgt ccgattttgg cggaggttca ggctttagta acaccgacca tgtttggaaa
    41341 tgccaagcgt actacgacag gacttgattt taaccgtgct agcttgatta tggctgtttt
    41401 ggaaaaacgg gcagggcttc tcttgcaaaa tcaggatgcc tatctcaaat ctgctggtgg
    41461 tgttaaattg gatgaacctg ccattgactt ggctgttgca gttgctattg cttcgagcta
    41521 caaagacaaa ccaactaatc ctcaggaatg ttttgtcgga gaactgggct tgacaggaga
    41581 gattcggcgc gtgaatcgta ttgagcaacg catcaacgaa gctgctaaac tgggctttac
    41641 taagatttat gtacctaaga attccttgac aggaatcact ctgcctaagg aaattcaggt
    41701 cattggcgtg acaacgattc aggaagtttt gaaaaaggtc tttgcataat ccgtgacaaa
    41761 ttctcttaaa aatgataaga taggagaaat atttgactat caaattttca aggagggaat
    41821 cgtgtcgtat tttgaacagt ttatgcaagc caatcaggct tatgttgccc tacatgggca
    41881 gttaaatctg ccacttaaac ccaaaacaag agtagctatt gtgacctgta tggactctcg
    41941 tctgcacgtt gcgcaagctc tgggcttggc acttggggat gctcatatct tgcggaatgc
    42001 aggtggtcga gtgactgaag acatgattcg ttcgctagtt atttcccagc aacaaatggg
    42061 gacaagagag attgtggtat tgcaccatac agactgtggt gctcagacct ttgaaaatga
    42121 accttttcag gagtatttaa aagaggaatt aggtgtagat gtgtcagacc aggatttctt
    42181 gcccttccaa gatatagaag agagtgtacg cgaggatatg caactgctta tcgagtctcc
    42241 cctaatacca gacgatgtca ttatctctgg tgccatttac aatgttgata caggaagtat
    42301 gacagtcgta gaattataaa tacttcattt agaaagaaag tgtatgaaga aaagcagtat
    42361 tttattgcta tgtattggtt tacagtatga aaccatctac tatacggacg gttcgaggtc
    42421 aggtgcggaa tatggactaa tgggaatttc tatctttcta gctctctttt acatgattcc
    42481 ggctctttat tttctcttcc gtattgggaa aaatgggaat tgccaaagaa ggttttgatt
    42541 ctgtctttat tgggagggat gttcctttca ggctggttgt ctagttttgc taatacttat
    42601 atccatgatt tactgggggt tcttttccca gatagtacat ttttaaatgc ctttgaaagt
    42661 gctattgtgg ctcctttggt agaagaaccc ttgaaattat tgccacttgt ttttgttttg
    42721 gctttgattc ctgtgcgaaa attaaaatct ttgtttttac ttggaattgc ttccggtttg
    42781 ggattccaaa tgattgagga tattggttat attcgtacgg atttgccaga gggctttgac
    42841 tttactattt cgcgaatttt agagcgtatc atctcaggaa ttgcctctca ctggactttt
    42901 tcaggtctag ctgtagtagg tgtttacttg ctttacagag cctataaagg acagaaggtt
    42961 ggcaagaaac agggccttat ttttctaggt ttagccttgg gaactcactt cttgtttaac
    43021 tctccttttg tggagttgga aacagagttg cctttagcga ttccagtggt tacggctatt
    43081 gctctctatg gtttttatca tgcttattgc tttgttgaga aacacaatga gttgatgacc
    43141 tagaatattt ttcaaaagaa tgatgcaagg gtacaaatat ggtgcccttc ttttattttt
    43201 gattgaaaaa tagtgcaaaa agcgctacaa tggtagatgg aaaatcttgt gaaaggcaca
    43261 agttatacat atataccgga ggaaatcatg tctttttctg atttaaagct gtttgccctt
    43321 tcttctaata aagaattggc agaacgtgtg gcgcaggaga ttgggataga gttggggaaa
    43381 tcaagtgttc gccaattttc agatggagag attcaggtca acattgaaga atcaatccgt
    43441 gggaaacacg tctttatctt acaatcaact agttcgcctg taaatgacaa tctgcttgaa
    43501 attttgatta tggtagatgc tttgaagcgt gcgagtgcag aatctgtcaa tgttgtcatg
    43561 ccttactatg ggtatgcacg tcaggataga aaggcgagag cgcgtgagcc aatcacttca
    43621 aaacttgtcg caaatatgct tgaagtagct ggagtggatc gtttattgac catcgacttg
    43681 catgctgcgc aaattcaagg attctttgat attcctgtgg atcatttgat gggtgctcct
    43741 ctgattgcag attattttga gcgtcgtggt atggttggtt ctgactatgt ggttgtcagc
    43801 ccggaccatg gaggggtgac tcgtgctcgt aagttggcag aatttttgaa aacatctatc
    43861 gctattattg ataaacgtcg tagcgttgat aagatgaata ctagtgaagt tatgaatatc
    43921 atcggtaagg ttgaaggcaa gacttgtatc ttgattgatg atatgattga taccgctgga
    43981 acgatttgtc atgcggcaga tgctcttgcg gaagctggtg ctgttgaagt ctatgcaagc
    44041 tgtacgcacc cagttctttc tggtcctgct acggacaata tccaaaaatc agctattaag
    44101 aaattggttg ttttggatac catctatctg ccagaagagc gtttgattga taagattgag
    44161 cagatttcaa tcgctcatct cctaggggat gctatcgtac gtattcatga aaaacgacca
    44221 ctttctccac ttttcgatat tgagaaaaaa atttaatgac caagcctgag atgattctca
    44281 ggttttttcg tcttttttcc gaataaatag atagtagcgg tgaatctagt aaagctagat
    44341 ttaaaactgt gatataataa aaagagaaga aatatgactg tacgtcatca gaagtttcag
    44401 cgaccatcat ttttgaacag tgatagcact tgaatcgacg ctttctaagg agaattctag
    44461 taggcatacc agtcgtttca agataaggaa ttttagaagg t
//
LOCUS       DAVBOM010000010        43433 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBOM010000010 DAVBOM010000000
VERSION     DAVBOM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.010"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ878_000603"
     tRNA            1..73
                     /locus_tag="VQ878_000603"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ878_000604"
     tRNA            87..160
                     /locus_tag="VQ878_000604"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ878_000605"
     tRNA            171..260
                     /locus_tag="VQ878_000605"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            271..344
                     /locus_tag="VQ878_000606"
     tRNA            271..344
                     /locus_tag="VQ878_000606"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:305..307,aa:Met,seq:cat)
     gene            348..420
                     /locus_tag="VQ878_000607"
     tRNA            348..420
                     /locus_tag="VQ878_000607"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:381..383,aa:Phe,seq:gaa)
     gene            440..510
                     /locus_tag="VQ878_000608"
     tRNA            440..510
                     /locus_tag="VQ878_000608"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Gly,seq:tcc)
     gene            546..619
                     /locus_tag="VQ878_000609"
     tRNA            546..619
                     /locus_tag="VQ878_000609"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Ile,seq:gat)
     gene            626..713
                     /locus_tag="VQ878_000610"
     tRNA            626..713
                     /locus_tag="VQ878_000610"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Ser,seq:gct)
     gene            complement(839..1774)
                     /locus_tag="VQ878_000611"
     CDS             complement(839..1774)
                     /locus_tag="VQ878_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET3094995.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1771..2631)
                     /locus_tag="VQ878_000612"
     CDS             complement(1771..2631)
                     /locus_tag="VQ878_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET3094996.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2739..4901
                     /locus_tag="VQ878_000613"
     CDS             2739..4901
                     /locus_tag="VQ878_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET3094997.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTEILVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4993..6252
                     /locus_tag="VQ878_000614"
     CDS             4993..6252
                     /locus_tag="VQ878_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3094998.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6266..7132
                     /locus_tag="VQ878_000615"
     CDS             6266..7132
                     /locus_tag="VQ878_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3094999.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7146..7979
                     /locus_tag="VQ878_000616"
     CDS             7146..7979
                     /locus_tag="VQ878_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3095000.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ878_000617"
     CDS             8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ878_000617"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET3095001.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKHLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9917..11110
                     /locus_tag="VQ878_000618"
     CDS             9917..11110
                     /locus_tag="VQ878_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET3095002.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11797..13776
                     /locus_tag="VQ878_000619"
     CDS             11797..13776
                     /locus_tag="VQ878_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3095003.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVEVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13843..15339
                     /locus_tag="VQ878_000620"
     CDS             13843..15339
                     /locus_tag="VQ878_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095004.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15339..16265
                     /locus_tag="VQ878_000621"
     CDS             15339..16265
                     /locus_tag="VQ878_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095005.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16274..17341
                     /locus_tag="VQ878_000622"
     CDS             16274..17341
                     /locus_tag="VQ878_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095006.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17352..18278
                     /locus_tag="VQ878_000623"
     CDS             17352..18278
                     /locus_tag="VQ878_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095007.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18769..19284
                     /locus_tag="VQ878_000624"
     CDS             18769..19284
                     /locus_tag="VQ878_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3095008.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TPPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            19306..19707
                     /locus_tag="VQ878_000625"
     CDS             19306..19707
                     /locus_tag="VQ878_000625"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095009.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            19719..20596
                     /locus_tag="VQ878_000626"
                     /pseudo
     CDS             19719..20596
                     /locus_tag="VQ878_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20609..21412
                     /locus_tag="VQ878_000627"
     CDS             20609..21412
                     /locus_tag="VQ878_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3095010.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ878_000628"
     CDS             complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ878_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET3095011.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            22340..24307
                     /gene="treP"
                     /locus_tag="VQ878_000629"
     CDS             22340..24307
                     /gene="treP"
                     /locus_tag="VQ878_000629"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET3095012.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24485..26110
                     /gene="treC"
                     /locus_tag="VQ878_000630"
     CDS             24485..26110
                     /gene="treC"
                     /locus_tag="VQ878_000630"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET3095013.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26252..26500
                     /locus_tag="VQ878_000631"
     CDS             26252..26500
                     /locus_tag="VQ878_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET3095014.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26707..27501
                     /gene="racE"
                     /locus_tag="VQ878_000632"
     CDS             26707..27501
                     /gene="racE"
                     /locus_tag="VQ878_000632"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET3095015.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27498..28469
                     /locus_tag="VQ878_000633"
     CDS             27498..28469
                     /locus_tag="VQ878_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET3095016.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNLHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28445..28966
                     /locus_tag="VQ878_000634"
     CDS             28445..28966
                     /locus_tag="VQ878_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET3095017.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28963..29424
                     /locus_tag="VQ878_000635"
     CDS             28963..29424
                     /locus_tag="VQ878_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3095018.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29415..30155
                     /gene="xerD"
                     /locus_tag="VQ878_000636"
     CDS             29415..30155
                     /gene="xerD"
                     /locus_tag="VQ878_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET3095019.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30155..30883
                     /locus_tag="VQ878_000637"
     CDS             30155..30883
                     /locus_tag="VQ878_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET3095020.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30902..31471
                     /locus_tag="VQ878_000638"
     CDS             30902..31471
                     /locus_tag="VQ878_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET3095021.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31458..32180
                     /locus_tag="VQ878_000639"
     CDS             31458..32180
                     /locus_tag="VQ878_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3095022.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLIIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            32180..32422
                     /gene="yidD"
                     /locus_tag="VQ878_000640"
     CDS             32180..32422
                     /gene="yidD"
                     /locus_tag="VQ878_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET3095023.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32647..33612)
                     /locus_tag="VQ878_000641"
     CDS             complement(32647..33612)
                     /locus_tag="VQ878_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3095024.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33708..34460)
                     /locus_tag="VQ878_000642"
     CDS             complement(33708..34460)
                     /locus_tag="VQ878_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3095025.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34457..35413)
                     /locus_tag="VQ878_000643"
     CDS             complement(34457..35413)
                     /locus_tag="VQ878_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET3095026.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35403..36362)
                     /locus_tag="VQ878_000644"
     CDS             complement(35403..36362)
                     /locus_tag="VQ878_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095027.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSEGLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ878_000645"
     CDS             complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ878_000645"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3095028.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37888..38952
                     /gene="pepA"
                     /locus_tag="VQ878_000646"
     CDS             37888..38952
                     /gene="pepA"
                     /locus_tag="VQ878_000646"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET3095029.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38974..39270
                     /locus_tag="VQ878_000647"
     CDS             38974..39270
                     /locus_tag="VQ878_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3095030.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39952..40395
                     /locus_tag="VQ878_000648"
     CDS             39952..40395
                     /locus_tag="VQ878_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3095031.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40399..41163
                     /locus_tag="VQ878_000649"
     CDS             40399..41163
                     /locus_tag="VQ878_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET3095032.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            41178..41906
                     /locus_tag="VQ878_000650"
     CDS             41178..41906
                     /locus_tag="VQ878_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095033.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41899..43419
                     /locus_tag="VQ878_000651"
     CDS             41899..43419
                     /locus_tag="VQ878_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET3095034.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12539 a         8075 c         9795 g        13024 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattaa cgcgggatgg agcagctcgg tagctcgtcg
      301 ggctcataac ccgaaggtcg taggttcaaa tcctgctccc gcaataaggc tcggtagctc
      361 agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg tctcgcgcca
      421 ttttattgat agtatttatg cgggtgtagt ttagtggtaa aactacagcc ttccaagctg
      481 ttgtcgcgag ttcgattctc gtcacccgct ttgaactttg ttcaaattac caagtttttt
      541 aacttgggcg cgtagctcag ttggttagag cgcacgcctg ataagcgtga ggtcggtggt
      601 tcgagtccac tcgtgcccat taattggaga attactcaag aggctgaaga ggacggtttg
      661 ctaaatcgtt aggtcgggta actggcgcaa gggttcgaat cccttattct ccgttttaat
      721 gagagtctgt aactctcttt tttattttta gagccaataa aacttcagat ccgtaaaact
      781 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      841 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      901 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      961 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
     1021 atagctcttc tgctggtgtt tcgaagaaag cacgccagat ttctatgatc aattcattcc
     1081 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
     1141 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
     1201 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
     1261 cattgaccca ttttatgtcg acatctatta aagttaggtt cttaatggct ttgtagacag
     1321 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
     1381 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
     1441 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
     1501 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
     1561 tttcttctag aatctctgga agaataaggt caccattcat cagtttatat cctctatttt
     1621 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgctg
     1681 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1741 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctta ctagttggta
     1801 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1861 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1921 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1981 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     2041 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     2101 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     2161 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     2221 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     2281 atgacaagtt tcagattgga tgagatagga ttgatcagaa atttgggaaa gagcaaaata
     2341 atcaggggct ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     2401 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     2461 aacaatttta cccttgtaat gaaattttcc ttgtccttta gtaatgtaat gtagaacgta
     2521 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     2581 gcttagggca aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     2641 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     2701 tgataaaata taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2761 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2821 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2881 aacgagacca tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata
     2941 ctcagcgaca gatttttgga caacatggct taggagattt taggaaacca accatacagg
     3001 ttcagcatag tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag
     3061 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagattcttg
     3121 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     3181 ataatgatgc gactattgct agctacagta aattagataa taatagtaat caggaagttg
     3241 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagtaa
     3301 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     3361 tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     3421 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     3481 gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg
     3541 gcattaatcc agaaaacttt tcttggaagt tagctcctga ggaatacttt gaaacaccgg
     3601 tagctttagt gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     3661 ttgtactgaa gcacattatg ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3721 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3781 aagctaagaa agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3841 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3901 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3961 ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca tcctgactgg gctattcagg
     4021 ttcctggcta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     4081 aggtagtaga atacttgaaa agtgtcttag atcaactcct attttatcat gatattgatt
     4141 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     4201 agacacagat gcaatctcat cagtacatgc tggggcttta tgaactcgtt tcttatctga
     4261 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     4321 ttggtatgat gcgctatttc ccacaagtct gggctagtga taatactgat gccattgcac
     4381 gtttaccaat tcaatacggt tcatcctatc tctatccaac catttctatg ggggctcatg
     4441 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccttg
     4501 tagcaatgat gggaaatttg ggctatgaac ttgatttgac aaatttatca gatgaagaga
     4561 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     4621 gacagcagta tagactaatt aatcctgata ctgtatccaa tgaagcagct gtacaattta
     4681 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4741 aaacaacttt aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg
     4801 gcgaagttta ctcaggtgca gaactaatgt atgcgggctt aactgttatc ttatcccaag
     4861 gagatttttt gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag
     4921 ttagatttat tctgtctaac ttttggggtg cagttcaata agggtgtata aatttataaa
     4981 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     5041 ttgtttgggc tcggcgcttg ctccaactat ggtaaatctg cggatggcac agtgaccatc
     5101 gagtatttca accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt
     5161 gagaaggaaa accctaagat caaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta
     5221 ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc
     5281 atcgaactgc aagaatgggc aaaagcaggt gtttttgaag atttgagcaa caaagactac
     5341 ctgaaacgcg tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac
     5401 gttcctttta cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg
     5461 ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct
     5521 aaaggacaaa caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat
     5581 caattagcct ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat
     5641 tctcaaccaa atgccattaa attgtcggat ccgattatga aagatgatat caaggtcatg
     5701 gacatccttc gcatcaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat
     5761 gttatcggag ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc
     5821 acagcgatta atgaacaaaa accgaacttt aagattggga ccttcatgat tccaggaaaa
     5881 gaaaaaggac aaagcttaac cgttggtgcg ggagacttgg catggtctat ctcagccacc
     5941 accaaacatc caaaagaagc caatgccttt gtggaatata tgacccgtcc agaagtcatg
     6001 caaaaatact acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga
     6061 gaagattcac cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg
     6121 ttgcaacaat actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg
     6181 accggtgata aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg
     6241 gatgtggatt aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc
     6301 ttttgtggtc atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg
     6361 agccttttac agttttacca actggacagg attgacttat aactacaaat ttgttggctt
     6421 aaacaacttt aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc
     6481 aatcattgcg attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt
     6541 cttgaattct aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt
     6601 tttatctggt ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc
     6661 gattggaaat gcccttcata ttgaattttt ccaaaccagt cttttaggga ctaagtgggg
     6721 agcaatcttt gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat
     6781 cttcctagct ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg
     6841 tgcgactagc aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc
     6901 tatggtcttt atcctagccc taaaaggtgg gctgactgcc tttgaccaag tctttgccat
     6961 gaccggtggt ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc
     7021 ctttaaaaac aaccaattcg gttatgccaa tgccattgcc gtaatcttgt tcttcttaat
     7081 tgtagtgatt tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa
     7141 gcatgatgaa acaagatgaa agaaaagccc tgattggcaa atacattcta ttgattctag
     7201 gatcggttct gattttagtg ccgctccttg ctaccctctt tagttccttc aaacccacta
     7261 aggatattgt agataatttc tttggctttc caaccaactt cacatgggac aactttagcc
     7321 gtctcttagc tgatgggatt ggaggctatt attggaactc tgtcgtcatc actgtcttgt
     7381 ctttacttgc agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga
     7441 gtaaaagaaa agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt
     7501 tccaagtcat catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct
     7561 ttggtttgat cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg
     7621 gctatatcaa aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta
     7681 atcaatttac aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa
     7741 ccatgatcat caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga
     7801 accgggattc caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt
     7861 tcaacgacta cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg
     7921 tctatctctt cttccaacgc catatcattt caggaatgag caacggggca gtgaagtaat
     7981 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt
     8041 ttgaggttgt ggatgaaact gacgaagtca gtaaccatac ctacggcaag gtgaagctga
     8101 cgtggtttga agagattttc gaagagtata agaagagctc atggaatcta tagtctttga
     8161 cacagaggaa gagtttagct tgttgataat tctatgcaga aaacaagaaa gtagtacttt
     8221 gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa aatgaatttt
     8281 atttatgaag ccagatcata tgagacttgg cttcaattag aaaaaggaga gtaatgatgc
     8341 caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat aatcttaaag
     8401 acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt caccttttac
     8461 catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgac gaagtggact
     8521 cagcttttgg tgattgggag gatgttaagc atttaggtga gaaatattat cttatgtttg
     8581 attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat caagaaaaac
     8641 atgaagccag tgaatttaaa gctctctttt taaactggga taagttttgg ccagaaaacc
     8701 gtccgacaca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag
     8761 agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt gaggagcaga
     8821 ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc attcagcact
     8881 tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat
     8941 tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac aaagttcgag
     9001 atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac tattcgattc
     9061 agtttaaaat agcagaccat gattactatg tttatgattt tgctcttcca atggtgacac
     9121 tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag atgagcccga
     9181 tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat gtcaaggata
     9241 tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt ggagccaatg
     9301 tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa atcaattcaa
     9361 cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt ctaattcaag
     9421 cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc aagaatgact
     9481 tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac tatagcaacg
     9541 aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc ccttctcaat ctattttctt
     9601 tccgtaaccg ttcagaagcc tttgatctag aagggactac tgagatagag acaccaacag
     9661 ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca gtagcagaaa
     9721 ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta acattttgaa
     9781 gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct ttgttttcaa
     9841 attgctaaaa aagtggtaca atataggaca gcttactatt atctgaatca gctgatttgg
     9901 agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg ggttgtctag
     9961 taaagagctg attttattgg gaattatcct aagtatcttt ttaccctttt atctttttgt
    10021 agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga aaagtattct
    10081 tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta ctgttatatc
    10141 cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc tatttactat
    10201 tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga ttttgcagtt
    10261 cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt tccaaattgt
    10321 gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc agaaccgggc
    10381 agaagtgacc ttctttaatc ctaattatta tggaattatt tgttgtttct gtattatgat
    10441 tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct gtgtgattgc
    10501 aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct ttcctgctat
    10561 tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg ccttttggct
    10621 tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt tgggagttcg
    10681 aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg ctgggatggc
    10741 cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc actcttatcc
    10801 tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata cgattctgag
    10861 ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg ttcgcttgat
    10921 gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc tatctttcct
    10981 tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc agtcaggctt
    11041 tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg tatcggacat
    11101 gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt tttttatacg
    11161 atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac cggtgaatac
    11221 aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga
    11281 tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt gaaatcgtag
    11341 gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg agaaatttta
    11401 aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg aattcggaat
    11461 aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga tacttctaca
    11521 atattgttat aatttaattt gaattccaaa atcacattgt ttcgtccgta tttcatttta
    11581 ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc actgtagtct
    11641 ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaatgaaaa atttgtgcca
    11701 acaagcctaa atattctgaa aatttgtttg atttttaatg gataatgtga tataatggtt
    11761 gtcaatctat aattcacata aacagaggag tagaaaatga aaaaaaatcg tgtatttgct
    11821 acagcaggtc ttgttttatt agcagcaggt gtacttgcag catgcagttc ttcaaaatca
    11881 tctgattcat cagcccctaa agcttatggc tatgtttata cagcagaccc agaaaccttg
    11941 gactacctga tttcaagtaa aaatagtaca acagtagtga cttcaaatgg gattgatggt
    12001 ttattcacta acgataatta cggtaatctt gctcctgcag ttgcagagga ttgggaagtc
    12061 tctaaggatg gtttgaccta cacttataag attcgtaaag gggttaaatg gtttacctct
    12121 gatggagaag aatatgcaga ggtgacggct aaagatttcg tgaacggttt aaaacacgca
    12181 gcagataaaa aatcagaagc tatgtattta gctgaaaatt cggttaaagg cttggcagat
    12241 tatctatcag gaacttcaac agatttttca acagttggtg tcaaggcggt tgatgattat
    12301 acgttacaat acactttgaa ccagcctgaa ccgttctgga actctaagtt gacctattct
    12361 attttctggc ctctgaatga agaattcgaa acatcaaaag gaagcgattt tgctaaacca
    12421 acagatccga catccttgct ttataatggt ccattcttgt tgaaagggtt gactgcaaaa
    12481 tcttctgtag agtttgtaaa aaatgagcaa tattgggata aagaaaatgt ccacctagat
    12541 actatcaatc tagcttacta tgatggatca gatcaggagt cgctagagcg taacttcact
    12601 agtggagctt atagttatgc ccgtctttac cctaccagct ccaactattc taaggttgca
    12661 gaagaataca aggacaatat ctattacaca caatcaggct ctgggattgc tggtctgggt
    12721 gtgaatattg atcgccaaag ttacaactat acttctaaaa ctacagattc agagaaagta
    12781 gctactaaga aggcattgct taacaaagat ttccgtcaag ccttgaattt tgctcttgat
    12841 cgctcagctt actcagctca aatcaatggt aaagatggag cagctttagc agttcgtaat
    12901 ttatttgtaa aaccagactt tgtttcagct ggtgagaaga cctttggtga tttagtcgct
    12961 gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga atttagctga tgggcaggat
    13021 ggtttattca atgctgacaa ggccaaggca gagtttgcga aagctaagaa agctttagaa
    13081 gcagacggcg ttcagtttcc tattcatctg gacgttccag tagaccaagc atcaaaaaac
    13141 tacatatctc gtattcagtc ctttaaacaa tctgtagaaa cagttcttgg tgttgaaaat
    13201 gtcgttgttg atattcaaca aatgacaagt gatgaattcc ttaatattac ttactatgct
    13261 gccaatgctt catctgagga ttgggatgta tcaggaggag tttcatgggg gccagactat
    13321 caagacccat ctacttacct ggatatttta aaaacaacta gcagtgaaac tacaaaaaca
    13381 tatttaggat ttgataatcc aaatagccct tcagtagttg aagttggttt gaaagaatac
    13441 gataaattag ttgatgaagc tgccagagag acaagcgact tgaatgtccg ttatgaaaaa
    13501 tatgcagcgg ctcaagcatg gttgacagat agttcactct ttattcctgc tatggcttct
    13561 tctggtgcag caccagtgct ttcacgaatt gttccattta ctggagcttc tgcgcaaaca
    13621 ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat tacaagataa agtggtgact
    13681 aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag aaaaagctga atcaaatgag
    13741 aaagctcaaa aagaattggc aagtcatgtg aagtaaataa tttctaatag aactttctct
    13801 ccatgaggag aaggttcttt tgggattttt aaaggaaata atatgaaaaa atatattttt
    13861 atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa cgactttgac ctacacgatt
    13921 atctatacct tggttcctcg aaaattgatt ttcaagcagg atcctaacta taataaaatt
    13981 gcgacaacgg ctgataaacg tgataactat gaaaatactg tgtttgagcg tatgggctac
    14041 attgagtatt acgatactaa agagttgcaa gaaaaggcaa gtagcatgga ttcttctgta
    14101 acagtagaag caaatgcgac caataaagct atttatgaaa agtacatcaa tcaattaggt
    14161 catggttgga ctttgggaga atttactgaa agtggtcaat tctatgctac tcgtgaaatt
    14221 ccaatttttg aacgtgtttt tcacttctat gctaacttga ttgacattga ccatacaaat
    14281 aaaatccaag accctgaaaa tccagacttg aaacgctacc ttcgttttga aaatgatcca
    14341 gctatcggat ggtcattggt cggttcagga actaaacata aatatctctt gtactttaac
    14401 agtcagttcc catttgttca tcaaaacttt gtgaacttga atttaggtga ctcttaccca
    14461 acctatgcta atacaccagt tcttcaggtt attactcaag gtcaaggaca aaccaaaact
    14521 gcccaagttc agttcccaac aggtaagaaa acgtcttctg taaatattta ctcaagaacc
    14581 tacaagtcac ctagtcaggc tgactctcgt gaagtagcta gctatgggaa agatgatcct
    14641 tatacagcga ctgaaagtaa ttaccaatat ccatctatga ttgtcagctc tgctattact
    14701 ggtttgattg gtttggttct tgcctatgct cttgccgtgc cacttggttc agccatggct
    14761 cgtttcaaga acacttggat tgatagcctc tcaacagggg ctttgacctt cttgcttgct
    14821 cttccaacga ttgccttggt ttacatcgtt cgattgattg gatcatctat tgcccttcca
    14881 gattcattcc ctatcttggg agctggagat tggcgttctt acgttttacc agcagtcatc
    14941 cttggtttgt tgggtgctcc tggtacagcc atttggattc gtcgttacat gattgacttg
    15001 caatctcaag actttgttcg tttcgctcgt gcaaaaggtt tgtctgaaaa agaaatttca
    15061 aacaaacaca tctttaaaaa tgccatggtt ccgctggttt caggaattcc tggtgccatt
    15121 attggggtta tcggtggtgc aacccttact gaaacagtct tcgccttccc aggtatgggt
    15181 aaaatgttga ttgactctgt aaaagcatct aataactcta tggtcgttgg tcttgtcttc
    15241 atctttacat gtatttctat cttctcacgt cttttgggag atatttggat gactattatt
    15301 gacccacgta ttaaattgac tgagaaagga ggcaaataat gtctacaatc gataaagaaa
    15361 aatttcagtt tgtaaaacgt gacgattttg cctctgaaac tattgatgcg ccagcatatt
    15421 cttactggaa atcagtgttt aaacaattta tgaagaaaaa atcaactgta gtcatgttgg
    15481 gaatcttggt agccatcatt ttgataagtt tcatctaccc aatgttttct aagtttgatt
    15541 tcaatgatgt cagcaaggta aacgacttta gtgttcgtta tatcaagcca aatgcggagc
    15601 attggttcgg tactgacagt aacggtaaat cgctctttga cggtgtctgg ttcggagctc
    15661 gtaactccat cctcatttct gtgattgcga cagtgattaa cttggttatc ggtgtttttg
    15721 tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt catgatggaa gtttacaacg
    15781 tcatctcaaa catcccacct cttttgattg ttattgtctt gacttactca atcggagctg
    15841 gattctggaa tctgattttt gccatgagcg taacaacatg gattggtatt gccttcatga
    15901 tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa cttggcgtca cgtactttgg
    15961 gaacaccaac cttgaagatt gttgccaaaa atatcatgcc tcaattggta tctgttattg
    16021 tgacaaccat gactcaaatg cttccaagct ttatctcata cgaagccttc ttgtctttct
    16081 tcggtcttgg attaccgatt acagtgccaa gtttgggtcg tttgatttcg gattattcac
    16141 aaaacgtaac aaccaatgct tacttgttct ggattccatt gacaaccctt gtcttggtat
    16201 ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc tagtgatcca cgtacacata
    16261 gataggagta gaaatgacaa aagaaaaaaa tgtaattttg actgctcgcg atattgtcgt
    16321 ggaatttgac gttcgtgaca aagtattgac agccattcgc ggcgtttccc ttgaactagt
    16381 cgaaggagaa gtattagcct tggtaggtga gtcaggatca ggtaaatctg ttttgacaaa
    16441 gaccttcaca ggtatgctcg aagaaaatgg tcgcattgcc caaggtagta ttgactaccg
    16501 tggtcaggac ttgacagctt tatcttctca caaggattgg gaacaaattc gtggtgctaa
    16561 gattgcgact atcttccagg acccaatgac tagtttggac cccattaaaa caattggtag
    16621 tcagattaca gaagttattg taaaacacca aggaaaaaca gctaaagaag cgaaagaatt
    16681 ggccattgac tacatgaata aggttggcat tccagacgca gatagacgtt ttaatgaata
    16741 cccattccaa tattctggag gaatgcgtca acgtatcgtt attgcgattg cccttgcctg
    16801 ccgacctgat gtcttgatct gtgatgagcc aacaactgcc ttggatgtaa ctattcaagc
    16861 tcagattatt gatttgctaa aatctttaca aaacgagtat catttcacaa caatctttat
    16921 tacccacgac cttggtgtgg tggcaagtat tgcggataag gtagcggtta tgtatgcagg
    16981 agaaatcgtt gagtatggaa cggttgagga agtcttctat gaccctcgcc atccatatac
    17041 atggagtctc ttgtctagct tgcctcagct tgctgatgat aaaggggatc tttactcaat
    17101 cccaggaaca cctccgtcac tttatactga cctgaaaggg gatgcttttg ccttgcgttc
    17161 tgactacgca atgcagattg acttcgaaca aaaagctcct caattctcag tatcagagac
    17221 acattgggct aaaacttggc ttcttcatga ggatgctcca aaagtagaaa aaccagctgt
    17281 gattgcaaat ctccatgata agatccgtga aaaaatggga tttgcccatc tggctgacta
    17341 ggaggaagga aatgtctgaa aaattagtag aaatcaaaga tttagaaatt tccttcggtg
    17401 aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt ctttatcaac aagggagaaa
    17461 ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac tattggtcgt gctatcatcg
    17521 gtctaaatga tacaagtaat ggagatatca tttttgatgg tcaaaagatt aatggtaaga
    17581 aatcgcgtga acaagctgcg gaattgattc gtcgaatcca gatgattttc caagaccctg
    17641 ccgcaagttt gaatgaacgt gcgactgttg attatattat ttctgaaggt ctttacaatc
    17701 accgtttatt taaggatgaa gaagaacgta aagagaaagt tcaaagtatt atccgtgaag
    17761 taggtcttct tgctgagcac ttgactcgtt accctcatga attctcaggc ggtcaacgtc
    17821 aacgtatcgg tattgcccgt gccttggtca tgcaaccaga ctttgttatt gcagatgagc
    17881 caatttcagc cttggacgtt tctgtacgtg cccaagtctt gaacttgctc aaaaaattcc
    17941 aaaaagagct cggcttgacc tatctcttca tcgctcatga cttgtcggtt gttcgcttta
    18001 tttcagatcg tatcgcagtt atttacaagg gtgttattgt agaggttgca gaaacagaag
    18061 aattgtttaa caatccaatt cacccatata ctcaagcctt gctttcagca gtaccaatcc
    18121 cagatccaat cttggaacgt aagaaggtct tgaaggttta cgacccaagt caacacgact
    18181 atgagactga taagccatct atggtagaaa tccgtccagg tcactatgtt tgggcgaacc
    18241 aagccgaatt ggcacgttat caaaaaggac taaactaata atggttttat aatttccatg
    18301 tcaattttta tgggaattat aaaacttttt ttgttggact gatttgaaaa actttgaaag
    18361 cttcctgaaa gaattttcga aaaattttaa aaaattttga aatattattg acaggtgatg
    18421 aaaaaggtgg taggatagga aggatcaaaa aagaaagcag aaaaagaaat gaataagaga
    18481 caagccgtaa ctatgaatca aaacttttac tttagctact ttagatagtg tttgtagaca
    18541 tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta tctatgtggc taagattttt
    18601 gattgtggtc catatagatg aatatctaaa tggactagct aagttgtaac ttgttaggtt
    18661 atttcaagta cccgtttaga tagtatctag gcggtttttt gttttatctt ttctgagaag
    18721 gagtttcatt atgaaagttg ttcgaaaatc actagccccc tcttggtagt ggggatcctc
    18781 ttgacttctc tgatcagttt gcatcagttg aaggcagata agaaaagaga tgtctttcgt
    18841 atcggtattt cgcagtttat tacccaccag tccttagacg ctactagaga aggatttgtg
    18901 gatgagctgg ccaaacaagg ctatgttgag ggggaaaata ttgagattga tttgcaaaat
    18961 gcacagggag aacaaagaaa tctaaaaacg atttcccagc aactagcaga atccagcgat
    19021 gtcgttctag ccatcgcaag gccttctgct cagagcttgg ccaatacgac gcaaacgcca
    19081 ccagttatct tttcagctgt aacagaccca gtcagtgcca agttggttga gtcaagagaa
    19141 catcctgggg gcaatgtaac tgggacaagc gatcagtcat cagatgccat ttcaacccaa
    19201 atcaatttga taaagaaagt gttgccaaag gctaaaacga ttggaatcct ctatactcag
    19261 agcgagccca attcggttgt ttaaaatgat gaagctaagc gacttctgaa agaaaaaggc
    19321 tttaccgttg ttgaaaaaac aatcttggac agtaataacg tcaaggcggc agcagagagt
    19381 ttgatggcag aggtggatat ggtttttgtc ccaactgata atatcatttc gtcaaccatg
    19441 gaaacagtta agcaggtttc tattaaacac aaggttccag tattcggtgg ttcaacagaa
    19501 atgattgctg ttggtgactt gtataactac ggaaccaatt atgaagaatt gggaagacag
    19561 acagctcgca tgctgattcg tgttttaaaa ggtgagaaac cagaaaatat agcagttgag
    19621 ttgcctgaaa aactggaatt gcataccaat caagaaatgg cagatgcatt gggaattgat
    19681 attagtaagt tagaaggcaa ggaataagga ggattaagat gaattttgtg ttatctagtt
    19741 tatcagaagg tttgttgtgg tcgattgtgg cgattggggt ctacttgact ttccgtattt
    19801 tggatattgc ggatataact gctgagggag cctttcctct gggggcagca gtcgttgtat
    19861 cacagataca ggcaggggca aatccttggc ttgcgacttt acttgctttg ctggcaggta
    19921 tggtagcagg tcttgtatca ggaatgctcc acaccaagat gaaaatccca gctctcttga
    19981 cagggattgt gaccttgaca gggctctatt caatcaatat taaaattatg ggcagtgtac
    20041 ccaatctttc cttgggagat tctgcaaccg tctttaaaca gttggcgagc ttgggtctga
    20101 caaatgaagg agctgttttc tcacttagtt tagtctgtct cttacttgtt tggtcttgac
    20161 ccttttgatg aaaacagaga ttggtttggt cttgcgttcg actggggata atatcccgat
    20221 aagtgaggcc aatggagtca atgtagacac catgaagatt gttggttaca tgatttcaaa
    20281 cggtttgatt gccctatgtg gttccttgtt tgcccaaaat gatggatttt cagatgtgac
    20341 ttctgggaca ggaaccattg ttgttggttt gagctcggaa gtcttgatac acgacttgac
    20401 cattggaggc cgcttattat ccatcggaat cggtgctatt gtttaccgtt tgattatttt
    20461 aaatatctat gaaattccaa atctagatca aaacttggta cgtctcttta atgcaatctt
    20521 gctcgctttg gttttatttg caccagaatt gcaaaagaga ttaaagattc gtggtctgaa
    20581 attgagaaat gaataggagg agaaagttat ggcaagtttg ttaacacttg aaaatattca
    20641 caagacattt gaagcaggga cggtcaatga gaaccatgtc ctcaaaggat tagatttaga
    20701 ggttgaagag ggagatttta tctatgtgat tggtggaaat ggagcaggaa aatccacttt
    20761 gatgaatatc ttggctggca atctatcggt ggacgaaggg gaccttctac tggcagggaa
    20821 atccattaaa aatctgagtg tcagaaagag agccaaggat attgcccgtg tttttcaata
    20881 tcctaagatg ggaacagctt ctcgtttgac gattgaggag aatatggcta ttgccttgag
    20941 acgtgggcaa aagagagggc ttggttgggg tgtgaaggag aaggatagaa tccagttcca
    21001 agaggccttg aaggagttga atattggtct tgaaaaccgc ttaaaagtag atactcaata
    21061 tctctcagga ggacaaagac aggctttgac cctagtcatg gcagctctgg tgaaacccaa
    21121 acttttactt ttggatgaac atactgcggc acttgacccg aaaaccagtc aaatggtgat
    21181 ggacttgacg caaaagattg tggagcacca tcagtggacg actttgatga ttacccatga
    21241 tatgaatcat gcgattgagt acggcaatcg tctcattatg ctctatcaag gcaagatagt
    21301 ggtggatgtc aagggagaag agaaaaagca tctgacagtt gaagacctta tgcatctctt
    21361 ccagaaaaat agtggccaaa gtctggtcag tgatgaatta gttttgggat aaagaaaaag
    21421 gctgagatct ggtgtctcag tcttttattt cttgcgtttt gcaaaatcta caaatctaaa
    21481 tttttctaac ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt ggagatagac
    21541 ttttgattta atcgaaacga cataagggtc tttgccaatg tccatgagaa tcttgtctcg
    21601 gtcgcttgag tggtcaatgg tgatttcctt ctgagcataa tcaataagga gtttgaggcc
    21661 attttctata taagaataga tagactgctc agcaatttgg cgagtgagat ttggaattag
    21721 ttccatatcc agatagtctg tatccagaac ggataccaga tcatccacca cacgctggcg
    21781 gaccaccttc caaaccatcc gaaactctgg gaaaccggtt atcagtgagg attttttatc
    21841 aataataatc ttgtccagac tgaccacgtt ggttttagag cgcagtccaa gttctttaac
    21901 tagttcttgg tagctggtta ggttggatac agggaaattg acggtttctt ctttgacgac
    21961 ttgagaacct tgccctctta tctttttgat caatccttcc tcttggagga gagacagggc
    22021 ctttcggacg gtatcacgac tcacttgata ttgctccata aggtcgtgct cgctaggaag
    22081 gaaatctccg acagcgtaag tctcgttttg aatggtttct tggatttgct taaataattg
    22141 ttggtatttc ttcattttgc ctgcttaaat aggtttttag tctagtttaa tgaacacctg
    22201 tatctatttt accatacaag tgctagaaaa tttacaaaaa aacacccttt ttataccaaa
    22261 caagttgcag acaagtttgg tatcgtttac aatatactta tcaaatcaaa cttgctttga
    22321 caagtataag gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc tgcttcaggc
    22381 aattggaggc aaagaaaatg tgactgccgt aactcactgt gcgacacgga tgcgctttgt
    22441 tttaggagat gataagaagg ctaatgttaa agctatcgag tcaattccag ctgttaaagg
    22501 aacttttaca aatgcaggtc aatttcaggt aatcattgga aatgacgtgc ccatctttta
    22561 taatgatttt acagccgttt caggtattga gggtgtttcc aaagaagcag ccaagtctgc
    22621 agctaagagt aatcaaaacg tggtccaacg tgttatgacc actctggcgg agatttttac
    22681 tccgattatt ccagccttga tagtcggagg attgatcctc ggtttccgta atgtcttgga
    22741 aggtgtccat tggtcgatgt tggatggcaa gaccatcaca gaatcctctc agttttgggc
    22801 aggtgtcaat cacttcctct ggttgcctgg tgaagctatc ttccagttct taccagtagg
    22861 gattacttgg tctgtttctc gtaagatggg aaccagccaa attttgggaa ttgttctcgg
    22921 aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa cgccagcagc
    22981 tgatatcgcg gcaaactggg tttggaattt tggctatttt actgttaatc gtatcggtta
    23041 ccaagcccaa gttatcccag ccttgcttgc aggtttgagt ctgtcttatc ttgaaatctt
    23101 ctggcgcaag catatcccag aagtcatttc tatgattttt gtacctttct tgtcattgat
    23161 tccagccttg attttggctc atactgtttt gggaccaatc ggttggacaa ttggacaagg
    23221 gctttcatca gttgtcttgg caggtttaac tggtccagtt aaatggctct tcggtgcaat
    23281 ttttggtgcc ctctacgctc catttgtcat cacaggtctg caccatatga ccaatgccat
    23341 tgatacacaa ttgattgcgg atgctggtgg cactgcccta tggccaatga ttgctctttc
    23401 taatattgct caaggctcag ccgtgtttgc ctattatttc atgcatcgcc atgatgagcg
    23461 tgaggctcag gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta cagaaccagc
    23521 tctttttggg gttaacgtaa aatatattta tccatttgtt gctgggatga ctggttcagc
    23581 ccttgcaggc atgttatccg ttacttttaa tgtaactgcg gcttctattg gtatcggtgg
    23641 tttgccaggt attctctcta ttcaacctca atacatgctg ccatttgcag gaactatgct
    23701 agttgcgatt gttgttccaa tgctcttgac tttcttcttc cgcaaggctg gtctctttac
    23761 aaaaacagag ggcgatacga acttgcaggc agaattcgtt gctcaagaag aagcagaatt
    23821 tgtgaaccat gaaccagtag aacttacttc ggtagaaatt atcagcccac taactggcca
    23881 agtgaaagaa ttgagtcaag cgacggatcc tatttttgca tcaggtgtca tggggcaagg
    23941 tctagtcatt gaaccaagcc aaggtgagtt gacctctcca gttaatggga cagtgacggt
    24001 tcttttccct accaagcatg ccatcggcat tgtctctgac gagggagttg aattgctcat
    24061 ccacatcggt atggatacag taggtcttga tggcaaaggt tttgaaagtc ttgtagtcca
    24121 aggagatcac gttacagttg gtcagcaact gattcgtttt gatatggatg tcattaaggc
    24181 tgcaggtctg gtgacagaaa ctcctgttat catcaccaac caagatgctt atacagcgac
    24241 tattcccgga acttatccga caacgatcca agctggagca tctctcatgg tcgctacacg
    24301 aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca acctcaaaat
    24361 agtgttttga gcaacctgtg gctagcttcc tagtttgttc tttgattttc attgagtata
    24421 attgaaatag cacaaatagg gacggaagac tgcttcctcc cttttatcag aaaaggagaa
    24481 acagatgaca cttgataaag gaaaagtagt ctatcaaatc tatccaaaat cttacaaaga
    24541 caccactgaa aacggtattg gggatttccg tgggattatc ggaaaaattc cctatctagc
    24601 caaactaggt gtggatatgg tctggctcaa tccattctat ccaagtcctc aacgggataa
    24661 tggttacgat atttcagatt atatggcagt ggatcctctt tttggtgata tggctgattt
    24721 tgaggaaatg gtgtgtatcg gtaaagagca caagattgac tttatgctgg acatggtact
    24781 taatcattgt tcgacagagc atgaatggtt tcagaaagcc ctagctggtg ataagtatta
    24841 tcaagacttt ttcttcatcc aagaccaacc aacagattgg cagtctaagt ttggtggttc
    24901 tgcatgggcg cctttcgggg atactgggaa atactatctt cacctatttg atgagaccca
    24961 ggctgacctt aactggcgca atcccaatgt ccgtaaggag cttttcaagg ttgttaattt
    25021 ctggcgcgac aagggtgtca aaggttttcg atttgatgtg atcaatttga ttggtaagga
    25081 cgaggtttca gtggactgtc ctgaaaatga agggaagcca gcttatacag acaaacccat
    25141 cgttcataac tatttgcgta tgatgaacca agccactttt ggatctgacg atagctttat
    25201 gacagttggg gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt cgtcgcctga
    25261 tcgtcaggaa ttatccatga cctttaattt tcatcacctc aaggtggact ataaggatgg
    25321 acaaaagtgg accttggctc cctttgattt tgaagagttg aagagtcttt accatagttg
    25381 gggtaaggaa atgagtgata aagacggttg gagtgccctc ttttggaaca atcacgatca
    25441 accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag gagccaccat
    25501 gctagcagcc agcattcacc tgtcacgtgg gacaccttat atctacatgg gtgaggaaat
    25561 cgggatgatt gacccagact atgattctat ggctgattat gtggatgtcg aatcgcttaa
    25621 tgcctatcag atgctcttag aagaaggaaa gagtcagcaa gaagccttcc agattattca
    25681 agctaagtcg cgtgataatt cacgcattcc catgcagtgg gatgcttcgg aaaatgcagg
    25741 attttcaaca ggcactcctt ggttgaaagc tggtaaatcc tataaataca tcaatgtaga
    25801 aaatgaaatc cagggtccga tttttacctt ctatcaagac ttgattcgac tgcgtaagga
    25861 aatgccaatc atttcagaag gaagttacaa accagccttt gaagatagca aacaagtcta
    25921 cgcttttgaa cgccagtttg aggatcaaaa gttactagtg ctcaataact tttatgctaa
    25981 agaagtggaa atcgacttgc cagcagtcta ccaaaatgga cagattttga tttcaaacta
    26041 tgaagatgca gaagtgtctg agaaaattct actaaaaccc tatcaaacac tggctattta
    26101 tgtaaattaa acttagcaag gagacctctt tttcagaaaa gcagggttct ttttgctgtc
    26161 tattccatcc ttgaaagtgt agaacaaact ggtcagggtg gctagtttgt ggtataatga
    26221 aagggactca aaaagaaaca ggagaaaaat gatggattta cttttagcaa ttgtattgat
    26281 tgtgctagct tttctaggag gagctcttgg aggaatgtac ttggttcgta agcaaatcga
    26341 aaaagaattt gctgacaacc cacgtttgaa tgctgaagca gttcgtactc ttttgagtgc
    26401 aaatggtcaa aaaccaagcg aagctaaggt acaacaagtt taccaccaaa tcatccgcca
    26461 acaaaaggca gcccttgcta acaataaaaa gaaaaaataa ataaggaaaa gtctgggatg
    26521 aaagttccag acttctcact atgttggtta tggtttaggg atgagacttt ttccttgcat
    26581 tctattgata tttgattatg attaagagag aggtagttga cattctatca agctgtcggt
    26641 cagttcgttc agtacaagga atcataatga acgatcaatc agaaaaaaga ctagaaagaa
    26701 gactgtatgg ataatcgacc aattggtttt ttggattcgg gtgtcggggg cttgaccgtt
    26761 gtgcgcgagc tcatgcgcca gcttccccat gaagaaatcg tctatattgg agattcggcg
    26821 cgggcgccct atggcccccg tcctgctgag caaattcgtg aatatacttg gcagctggtc
    26881 aactttctct tgaccaagga tgtcaaaatg attgtcattg cttgtaacac tgcgactgcg
    26941 gtcgtctggg aagaaatcaa ggctcaacta gatattcctg tcttgggtgt aattttgcca
    27001 ggagcttcgg cagccatcaa gtccagtcaa ggtgggaaaa tcggagtgat tggaacgccc
    27061 atgacggtac aatcagacat ataccgtcag aaaatccatg atctggatcc cgacttacag
    27121 gtggagagct tggcctgtcc caagtttgct cccttggttg agtcaggtgc cctgtcaacc
    27181 agtgttacca agaaggtggt ctatgaaacc ctgcgtccct tggttggaaa ggtggatagc
    27241 ctgattttgg gctgtactca ttatccactc cttcgcccta ttatccaaaa tgtgatgggg
    27301 ccaaaggttc agctcatcga tagtggggca gagtgcgtac gggatatctc agtcttactc
    27361 aattattttg aaatcaatcg tggtcgcgat gctggaccac tccatcaccg tttttacaca
    27421 acagccagta gccaaagttt tgcacaaatt ggtgaagaat ggctggaaaa agagattcat
    27481 gtggagcatg tagaattatg acaaataaaa tttatgaata taaggatgac caggactggt
    27541 atgttgggtc ttatagtatt tttggtggcg ttaacagttt gagcgactat cagacagatt
    27601 ttcctctgtt tgaattctcc aaaatatttg gagatgaaga gtatggtttc ccgctttcag
    27661 ttactgtttt acgctatggt tctacctacc gtttgttctc ctttgtggta gatatgctta
    27721 atcaagaaat gggacgaaac ttggaagtta ttcaacgtca tggggccctg ctcttggttg
    27781 aaaatgggca actcttgtat gtagaattgc ctaaagaagg ggtcaatctt catgatttct
    27841 ttgagacaag caaggtcaga gaaaccttgt tgattgcgac tcgtaacgaa ggcaaaacca
    27901 aggaattccg agctatcttt gataagttag gctacgatgt ggaaaatctt aatgactacc
    27961 ctgacctgcc tgaagtagca gaaacaggta tgacctttga agaaaatgcc cgccttaagg
    28021 cagaaaccat ttctcaatta acgggtaaga tggttttggc agatgattct ggtctcaaag
    28081 tcgatgtcct tggtggctta ccaggcgtct ggtcagctcg tttcgcaggt gtgggagcaa
    28141 ctgaccgtga aaataatgcc aaactcttgc acgaattggc catggtcttt gaactcaagg
    28201 accgctcggc tcagttccac acaaccctag tcgtagccag cccaaataag gaaagtttag
    28261 ttgttgaagc agactggtca ggttatatta actttgaacc taagggtgaa aatggctttg
    28321 gctatgatcc cctcttcctt gtaggagaga caggtgagtc atcagctgaa ttaaccctgg
    28381 aagaaaaaaa tagtcaatct caccgtgcct tagccgttaa gaaacttttg gaggtatttc
    28441 catcatggca aagcaaacca tcattgtaat gagcgattcc catggcgata gcttgattgt
    28501 ggaagaagtc cgtgatcgct atgtgggcaa agtcgatgcc gtttttcata acggcgattc
    28561 tgaactacgt ccggattctc cactttggga gggcatccgc gttgttaaag ggaacatgga
    28621 cttctacgcc ggctacccag aacgtctggt gactgagctt ggttcgacca agattatcca
    28681 aactcatggt cacttgtttg acatcaattt caactttcaa aagttggact actgggctca
    28741 ggaggaagag gccgctatct gcctctatgg tcacttgcat gtgccaagtg cttggatgga
    28801 aggcaagatc ctctttctaa atccaggttc tatcagccaa ccacgaggta ccatcagaga
    28861 atgtctctat gctcgtgtgg agattgatga tagttacttc aaagtggact ttttgacacg
    28921 agatcacgag gtgtatccag gtttgtccaa ggagtttagc cgatgattgc caaggagttt
    28981 gagactttct tgttggggca ggaggaaact tttttgaccc ctgctaaaaa tctagctgtg
    29041 ttgattgata cccacaatgc ggatcatgcg accctcttgc ttagtcagat gacctatacc
    29101 cgtgttcccg ttgtgacaga tgaaaaacag tttgttggga cgattggact cagagatatt
    29161 atggcttatc agatggagca tgacttgagc caagaaatca tggcggatac ggatatcgtt
    29221 catatgacaa aaacggacgt agcggttgtt tcgcctgatt tcaccattac ggaggtcttg
    29281 cacaagctag tagatgagtc cttcttaccg gttgtggata cagagggtat tttccaaggg
    29341 attattacgc gcaagtccat cctcaaggcc gttaatgccc tcttgcatga ttttagtaag
    29401 gaatatgaga ttcgatgcca atgagagaca gaatttcagc ctttttagag gaaaagcagg
    29461 gcttgtctgt caattccaag cagtcctata agtatgattt ggagcaattt ttagacatgg
    29521 taggtgagcg gatttctgag accagtctca agatttacca agcccagcta gccaatctaa
    29581 aaatcagcgc ccagaagcga aagatttcgg cctgtaacca atttctatac tttctctatc
    29641 aaaaaggaga ggtggacagc ttttaccgct tggaattagc caaacaagct gaaaagaaga
    29701 cggaaaagcc agagattcta tacctagact ctttttggca ggaaagcgac catccagagg
    29761 gccgcttgct agcgctctta atcctagaaa tggggctctt gcccagtgag attttagcca
    29821 tcaaggttgc ggacatcaat ctggattttc aggtgctgcg aatcagcaag gcttcccaac
    29881 agaggattgt caccattccc acggccttgc tttcagaatt ggaacccttg atggggcaga
    29941 cctatctttt tgaaagagga gggaaaccct attctcgtca gtgggccttt cgtcagttag
    30001 aatcttttgt caaggagaaa ggttttccat ccttatcagc tcaagtctta cgtgaacagt
    30061 ttattctaag acaaatagaa aacaaggtcg atttgtacga aattgcaaaa aaattaggat
    30121 taaaaacagt cctgacctta gaaaaatata gataatggat attaaattaa aagattttga
    30181 aggacccctg gacttactct tgcatctggt ttctaagtac cagatggata tctacgatgt
    30241 gcccattacg gaagtcatcg aacagtatct agcctatgtc tcaaccctgc aggccatgcg
    30301 tctggaagtg acgggtgagt acatggtcat ggctagtcag ctcatgctga ttaagagtcg
    30361 taaactcctt ccgaaggtag cagaagtgac agacttgggg gatgacctgg agcaggacct
    30421 cctctctcaa atcgaagaat atcgcaagtt caagctcttg ggtgagcact tggaagccaa
    30481 gcaccaagaa cgggcccagt attattccaa agcgccgaca gagttgattt acgaagatgc
    30541 ggagcttgtg catgacaaga cgaccattga cctctttttg gctttttcaa atatcctagc
    30601 caagaaaaaa gaggagtttg cacaaaatca cacgacgatc ttgcgggatg agtataagat
    30661 tgaggacatg atgattatcg tgaaagagtc cttgattgga cgagatcaat tgcgcttgca
    30721 ggatttgttc aaggaagccc agaatgtcca agaggtcatc accctctttt tggcaaccct
    30781 agagttaatc aaaacccagg agctgatcct cgtgcaagag gagagttttg gagatatcta
    30841 tctcatggaa aagaaggaag aaagtcaagt gcctcaaagc tagacttgat agagaggaaa
    30901 gatgagtact ttagcaaaaa tagaagcgct cttgtttgta gcgggtgaag atgggattcg
    30961 ggtccgccag ttagctgaac tcctctctct accaccgaca ggcatccagc aaagtttagg
    31021 aaaattagcc cagaagtatg aaaaggaccc agattccagt ttggctttga ttgagacaag
    31081 tggtgcttat agattggtga ccaagcctca atttgcagag attttgaagg aatactctaa
    31141 ggcgcctatc aaccagagct tgtctcgggc tgcccttgag accttgtcca ttattgccta
    31201 caaacagccg attacgcgga tagaaattga tgccatccgt ggagttaact cgagtggagc
    31261 cttggcaaag ttgcaggctt ttgacctgat aaaggaagac gggaaaaagg aagtattggg
    31321 gcgccccaac ctctatgtga ctacggatta tttcctagat tacatgggga taaaccattt
    31381 agaagaatta ccagtgattg atgagcttga gattcaagcc caagaaagcc aattatttgg
    31441 tgaaaggata gaagaagatg agaatcaata agtatattgc ccacgcaggt gtggccagta
    31501 ggagaaaagc agaagagctg attaagcaag gcttggtgac ggttaacggc caagtggtgc
    31561 gtgaactagc aaccactatc aagtcaggcg acaaggtcga agttgaaggt caacctatct
    31621 acaacgaaga aaaggtctac tatctgctta acaaaccacg cggtgtgatt tccagtgtga
    31681 cagatgataa gggtcgcaag acggttgtcg acctcttgcc caatgtcaaa gagcgtattt
    31741 accctgtggg tcgtttggac tgggatacat caggagtctt gattttgacc aatgatgggg
    31801 actttacaga cgagatgatt caccctcgta atgagattga caaggtttat gtcgcgcgtg
    31861 ttaaaggtgt ggccaataag gacaatctcc gccccttgac ccgtggtctt gagattgatg
    31921 gtaagaaaac caagccagct gtttatgaaa ttctcaaagt ggacccagtc aaaaatcgct
    31981 ctgtggtgca gttgatcatc catgaagggc gtaaccatca ggttaaaaag atgtttgaag
    32041 ctgttggtct ccaagtagat aagttgtctc ggactcgttt tggacaccta gacttgacag
    32101 gactccgtcc aggagaatcc cgtcgtctta ataaaaaaga aatcagccaa ctacacacca
    32161 tggctgtaac taagaaataa tgaaacgaat tttaatagcg cctgtgcgct tttaccaacg
    32221 ttttatctca ccagtctttc caccctcttg tcgctttgag ctgacttgtt ccaactacat
    32281 gattcaggct attgaaaaac atggttttaa gggggtattg atgggcttgt ctcggatttt
    32341 acgttgtcat ccctggtcga aaacaggtaa ggaccccgtt ccagaccgct tttcccttaa
    32401 acgaaatcaa gaaggggaat gaggtggggt aaatagattt caaaatgata aaaacgcatc
    32461 ctatcaggtt tgagtgaact tgataggatg cgttttagaa tgtcaaaatt ttatactctt
    32521 cgaaaatctc ttcaaaccgc gtcagctttc atctgcaacc tcaaaacagt gttttgagca
    32581 acctgcggct agttttctag tttgctcttt gattttcatt gagtattaaa ttgagtttga
    32641 agtggcttat ttcaaagctt tttgtatgtc ttcaatcatg agttttgttg attcaagtcc
    32701 gcctccgctt agataccaga ggtctggtgt tagttggata atcttaccat ttttagcagc
    32761 aggtgtttca gcgataaggg cattttctag gacaccgtcg ttgctagagt tgtccccacc
    32821 gatggcaagg gtacggttga tgacaaagag gatgtcaggg ttgatttctt tgacactttc
    32881 aaagctgact tcttgtccgt ggcgtgagtc ttcaaatgtt gtatcagttg gtttgaattt
    32941 caaggtttgg tacaagaaag agaaacgaga tttggcacca aaggctgcca tttttccttc
    33001 attaaggagg atcgcaaggg cttttttgtc agagctttca tttttagtag cgacttcttg
    33061 gatgctcttg tctagcttgg ccaattcttc cttggctttc tgtgtaccag tttcgccgaa
    33121 ggcacttgct aaggattcga tattagcctt ggtagaagtc cagtagtcgt ccttgcttgc
    33181 ttggaagaga acggttgggg cgatttcttt gaatttgtct acgaattttt gtgtacgtgg
    33241 tgaagcgata atcaaatcag gctcaagggc ggcgatagct tctaaatcag gttctttcat
    33301 agaaccaaca tttttgacag ttcccactag gtcttttaga taagtcggaa cagtttttgt
    33361 aggcattccg acgatatttt tttcaaatcc taaagcgcga atagtatccg cagcgccgag
    33421 gtcaaaggtc acaatctttt caggaacttt ggaaagtttg acctcgtcca gtgaactttt
    33481 aatggttacc tctgttggag cagagctact ggtctctgtc tgactagtgc ttgagtttgt
    33541 actacatgca ccaagtagga gcaagaagct ggccactagg gcagtgaaat aaagtttaag
    33601 ggatgttttc ataatttctc ctttttaaaa tgtgataacg atttagggag tctcttaatc
    33661 ttattgacta agagactgaa ggttctctaa cttgagcttt tatgttacta gctatagata
    33721 cagatctttt tgttattgat atcagctagc gtgatgggaa tctcataaag ttgactgagc
    33781 aggtcagcct gcatgatttg atcggttctt cccttgctaa agacctggcc gtccttgaag
    33841 gcgacaattt catctgcata ctgactggcc atgttgatat cgtggaggac gatgataatg
    33901 gtcttgccga gttcctccac cagtcgtcga agaatctgca tcatgctgac gctttgcttg
    33961 atatcgagat tgttgagtgg ttcgtccagc aagataaagt ccgtatcctg ggccagtacc
    34021 atagcgataa agacgcgctg gagttgcccc cctgacaggc tattgatgta gcggtctttt
    34081 aagttggtca gttccaaata gttcagagtt tctcggattt tttcccagtc ttctgatcta
    34141 agtcgacctc ggctgtaggg aaaacgtcca aaactgacca gttcttcaac agtcaatttg
    34201 gcttggtaat tgattttctg ttttaggatg gttagttctt gggccagttc ttgcgaattc
    34261 cagctctcga tttcacgtcc tttgatactg agaactccct gatctttctt ggttagtctg
    34321 ctcatgatgg agaggagagt cgattttcca gcaccatttg gaccaataaa ggctgtcagt
    34381 ttttgaggac tgacttcaag cgaaatgcct tgcaaaatat cctgtttttg aatggatttg
    34441 tcaatgtttt ccagtttcac tgacgagccc tcctatatag taagataaag aataagaagc
    34501 cacccacact ctcaatgatc atactgatac gaatttccag tgcaaagact cgttcaatca
    34561 aggcttgccc caaggttaag ctaataaatc caaccagaat ggccactata aagagtaact
    34621 tgtgctgata gtctttgaca atcaggtagg tgaggttggc cagcataaag ccgaagaagg
    34681 ccataggtcc taccaaggca gtggccgttg aggtcaaaag cacgattccc cagaggagct
    34741 ctttctgttc tttttcaaca tcgagtccca atatctgagc cgtttctctt tgcaggtgca
    34801 agacatctag aacgactgct tttcgaaaga aaaagattgt caaagcgagg atgatcagag
    34861 aaccgatggc taggatggaa gtgttaagat gttgaaagga ggcaaaaaga ctattttgca
    34921 gtttatcgta ttcgtttgga tccattagga cttgaaggaa ggtgctgata tttcgaaaga
    34981 gacttctgag cgctagacag atcagcagga tgaagaccag gtcttgcttc atcagtgtct
    35041 tcaagtaacc ttgtaaggcg agaaagaaga gggactggac aagaagtaag actaggaatt
    35101 ctaagatagg ggatttgccc agttgaagaa acttgctttc aaaaaccagt agtagggttt
    35161 gtagtaggac gtagaaggat tcaattccca aaatactagg cgtcaggaag cgattttccg
    35221 tcagggtttg aaaactaatg gtcgaaatcc cagtcgcgat ggctaccaag agataaacga
    35281 tgatcttttg ggaacgcaac ttccaagcaa aggctgacaa gtgagtgatg ggccaaaagt
    35341 agagaagaca agctccgatg gcaagaataa tgagaatcca gaagagcttg gtatgtttgc
    35401 ttttagtctg catcttttcg tccccctctc cagagaagta ggataaagac gagactaccg
    35461 atgattccta gcaagagact gacagacaac tcatagggcc taatcagaac tcgggatagg
    35521 atatcgcaag ccagaactag attggcacca accagtgcga ccatgagttt ggtttgactt
    35581 agattatctc catagcgctt gcgaacaaga ttgggaacga taactccgag aaatggtaag
    35641 ccacccacgg taatcatggt gacgcttgtc gttagcgcca ccagaaagag ggccagtttt
    35701 tcaagtaggg agtaggaaat ccccaaaccc tcgctggttt ctttccccag attcatgatg
    35761 gtgaaggttt gggataattt ccaaacggtt atcaggatga tgaggcctaa gaagagccac
    35821 tcatactgat gggtctgaat catggagaag gagccctggg tccaggcagt catactctga
    35881 accagattga aacgataggc gataacttct gtgactgagc cgataatccc gctatagatg
    35941 atcccaatca gaggcaacat ccacctttcc tttacagtaa aaatggtcat aaaggctagg
    36001 aagaagaggg tgaatacgat ggatgaaaca aaagcgaaga gcatcttttg ggtcagacta
    36061 gccgatggaa agacaaaaag gctcagcacc attcccagtt tggcggcttc agtcgttcca
    36121 actgtactcg gtgcagcaaa ctgattttgg gtaatagtct gcatgagaag gcctgccata
    36181 ctcatactag aggcagtcag gagaatactg atagttcttg ggagacggga ctcttgaaag
    36241 aggagccagg tctgctggtc gaaatcaaat agctttcccc atgaaaaatc actggtccca
    36301 atgctaatag agagaaagac taggagtaga agtaagccaa ttaaataatg agaaagtttc
    36361 ataccccgtc ctttcatgta gatttggtat cgaaagatat ctgcggatat aaatgtaaca
    36421 ttatttttct aatctgtcaa taaaatttct gacaatttaa taaatacaac aaggagagag
    36481 caacaagact ttctcctttg ttatcctatt ctaaaatgtt tttaccttaa tctgataaaa
    36541 taatatcttc gagggagtag ctagccgtcc aatcaagata ttgtttagct tttgaagcat
    36601 ctgctaggac actggctggg tcactagcac gtcgagcaac aatctcgtgt gggatttttt
    36661 aatttagtaa ttcttcagca gttttaaaga tttctttgat agtatagcct tttttagttc
    36721 ctaagttaaa gatttgagaa gaactgtctt cttgaaatag gtagttcatt cctttaacat
    36781 gagcctatgc aaggtccaag acataaatgt aatctcgaat acatgaaccg tcacgtgtat
    36841 cgtagtcatc tccaaatatt tttaagctat catgttgtcc caatgcggtc ttgttgatat
    36901 ttggaatgat gtgagttgga tttttcacac gcagaccgtt tgaagcatcc atttcagccc
    36961 cagcaacatt aaagtaacgg aaaataacat atttccagtc gtagcgattg gccatccagt
    37021 aaatcattcg ttcgcccatc agttttgtct ctgcataagg gttgacaggg tcgagcaggg
    37081 tatcttcagt caccggcttg tcaatacagt tatttccata gagagaagca gtcgaagaga
    37141 acatgatttt ttgaatgcca acttcagata agactttgag aacttggttc ataccagcaa
    37201 cgttggcagt gaagtattta cttggatttt caatactttc gctcacaaca atttcacctg
    37261 cacaatggag gacagcatca atctgatttt cttctaagta agcctttaag gcgctagcat
    37321 cataaacatc cagttcttta aagctagcac gactatccac agccgctcga tttcctgtgg
    37381 agagattatc gaggacatgc acctgatagc cagcatttaa aagagcttta acggtatggg
    37441 agccaatgta gctagtccca cctgtaacaa gaattgtttt ggtcatgatt ttttcctttt
    37501 ctagttttgt actatagtaa attgaaataa gatatgaaca actctattag gaaagtcgaa
    37561 ttaatttcta gaaatgtttc agcagctaca gcgtactatt ccaaactcaa ccaactatat
    37621 atttaaagaa agaagaaagg gaagtcaact attttctgta aatttcatga aaaatccaaa
    37681 caactttgat ggtgtattgt tttttttgtt tggaaataaa tattcgagtt aattttggaa
    37741 tgtttactag attttgcact acatgcaaga gaatactatc cttttctaag atagagcagg
    37801 actaagatac taacttagaa atccaccttc ccactatcct tctcctataa aaagtggtaa
    37861 aatggatgaa agaaagaagg aactgaaatg acaacattat tttcaaaaat taaagaagta
    37921 acagaacttg ctgcagtctc aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag
    37981 ttgacaccgc atgtggatga agtggtgaca gatggcttgg gtggtatttt tggtatcaaa
    38041 cattcagaag ctgtggatgc accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt
    38101 tttatggtca gcgaaatcaa gccagatggt accttccgtg tcgtagaaat cggtggctgg
    38161 aaccccatgg tagttagcag ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt
    38221 cctgtgattt caggttctgt tcctccgcat ttgactcgtg gaaagggggg accaaccatg
    38281 ccagccattg ccgatatcgt ttttgatggt ggttttgcgg acaaggatga ggcagaaagt
    38341 tttggcatcc gtcctggtga taccatcgta ccagatagtt ctgcaatttt gacagccaat
    38401 gaaaaaaata tcatctcaaa agcttgggat aaccgctacg gtgtcctcat ggtaagcgag
    38461 ctagctgaag ctttatcagg tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc
    38521 caagaagaag ttggtctgcg tggcgctcat acctctacaa ccaagtttga cccagaagtc
    38581 ttcctcgcag ttgattgctc accagcaggt gatgtctacg gtggtcaagg caagattgga
    38641 gatggaacct tgattcgttt ctatgatcca ggtcacttgc ttctcccagg gatgaaggat
    38701 tttcttttga caacggctga agaagctggt atcaagtacc aatactactg tggtaaaggc
    38761 ggaacagatg caggtgcagc tcatctgaaa aatggtggtg tcccatcaac aactatcggt
    38821 gtctgcgctc gttatatcca ttctcaccaa accctctatg caatggatga cttcctagaa
    38881 gcgcaagctt tcttacaagc cttggtgaag aaattggatc gttcaacggt tgatttgatt
    38941 aaacattatt aaaccataag ggaggtggta gggatggcag aaccaaacct agaaagcctt
    39001 ataaaagatc tttacaatca tgctcgacat gatttgagtg aagatttagt tgctgctctc
    39061 ctagagactg ctaaaaaact gcctactaca aatgagcaat tgcaggcagt tcgtctctca
    39121 ggcctggtca atcgtgaatt gctcctaaat cccaaacatc cagcacctga gttgctcaac
    39181 ttggctcgct ttatcaaaag agaagaagcc aagtacagag gaactgcgac ttctgcgctt
    39241 atgtatgagg aactctttaa aatgctttga ttccattgtg gatcaaagca ttttttgtaa
    39301 gatctatctc gtgagcgttc aaatagtagt aacaaggaat catgagaagt cagccgagcc
    39361 catagtagtg aagaaacttc tgtaatggaa gtggagcgaa gtgaggaatc gtcaaacggt
    39421 aggggatagg ctgtttgaag ggtgctacga aaaagatagg gtaaggtgaa attatagcgg
    39481 aatgaaataa gatatgaaca aattgattga ggaaattaaa tgaatttata gaaatctttt
    39541 agcagtcatg gtgtcctatt ccagtttcga aatgctataa atacgaacaa attgattggg
    39601 aaattcaaat cgctttctat caatgtttta gaagatacag tgctctagtc taacttcaat
    39661 atactataaa agaacagatg gaagcaatta tgatttactt ctatctttaa aataaatggt
    39721 ctgataggaa aaatgtgtcc cctcataaaa tataggatag tacgaatgga aggcttttgt
    39781 agactggagg acgaaggagt ttagaaactc tcgttaaaag ttagttgagc cggagtatgg
    39841 tggtgtggat aattatcaaa aattatttct aaatcgaaat agttgacagt tagaacgatg
    39901 agtgttacaa ttgttttatt catttcgata tcgaaataaa ttggaggtgt tatgaaagat
    39961 ggtcatttgc tagcccatca tattcgtttg ttgaatgggc ggatttttca aaagttactg
    40021 agtcaagatc ctgaggctct ttataggggt gaacagggca agattttagc ggttttatgg
    40081 aatagtgaaa ctggctgcgc aactgcgaca gatatcgcgc ttgcgactgg gcttgcgaat
    40141 aatacgctaa cgactatgat aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg
    40201 tgtggaaaag acaagcgtaa gaagtattta gttttaacgg agttaggcaa gtcccagaaa
    40261 gaagtggggc atcgtgtcag tcagaaattg gatactatct tttacaaagg attttcagag
    40321 gaagaaattc accaatttga aggttttcaa gaaagaattt tggcgaattt gaaagagaag
    40381 ggaaatgagg tttagaatat gtcacaacaa gtgaaaaatg ctcacaacct atacatccat
    40441 gccattcaag acggacgagt tgctgaggct caagcccagt ctgtagggga tacctatatc
    40501 caacattcga caggtgttcc tgacgggaaa gaaggatttg cagccttctt tgcagatttc
    40561 tttgagcgtc atccagagcg tcagattaag attgtccgca ccattgagga tggcaatctg
    40621 gtctttgttc atgttcatca atatctgaat ggtggagaag ctcaatgggt gacgacggat
    40681 actttccgtg cggatgagaa tggtcgtatt gttgagcatt gggatgtcat tgactactat
    40741 cgaacacctg aaaatgatca actagatcaa atttttggag attttgaaat caaggatttg
    40801 gacaagaaag cagaaaataa aaaactggtt cgccgtttct tgacagaaat tttccaaaat
    40861 ggggagctag agcagtggag tgattatgtg gcagacgatt tgattcagca taatcatgag
    40921 attggacaag gaagtgctgc ttataaaaac tatgtggctg aatatagtgt cacttttgac
    40981 tttgttttcc aactcttagg acaaggaaac tatgtggtta gctatggtca gactcagatt
    41041 gatggcgttg cttatgccca gtacgatatc ttccgtttag agaacgggaa aattgtggag
    41101 cattgggata ataaggaagt catgcctaag gtagaagact tgactaatcg agggaagttt
    41161 taaattgagg acaaagaatg attgaataca aaaatgtagc actgcgctac acagaaaagg
    41221 atgtcttgag agatgtcaac ttacagattg aggatgggga atttatggtt ttagtagggc
    41281 cttctgggtc aggtaagacg accatgctca agatgattaa ccgtcttttg gaaccaactg
    41341 atggaaatat ttatatggat gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc
    41401 tttctactgg ttatgtttta caggctattg ctctttttcc aaatctaaca gttgcggaaa
    41461 atattgctct cattcctgaa atgaaggggt ggagcaagga agaaattacg aagaaaacag
    41521 aagagctttt ggctaaggtt ggtttaccag tagccgagta tgggcatcgc ttacctagtg
    41581 aattatctgg tggagaacag caacgggtcg gtattgtccg agctatgatt ggtcagccca
    41641 agattttcct catggatgaa cccttttcgg ccttggatgc tatttcgaga aaacagttgc
    41701 aggttctgac aaaagaattg cataaagagt ttgggatgac aacgattttt gtaacccatg
    41761 atacggatga agccttgaag ttggcggacc gtattgctgt cttgcaggat ggagaaattc
    41821 gccaggtagc gaatcccgag acaattttaa aagtgcctgc aacagacttt gtagcagact
    41881 tgtttggagg tagtgttcat gactaattta attgcaactt ttcaggatcg ttttagtgat
    41941 tggttgacag ctctatctca acatttgcag ttgtcacttt tgaccttgtt actagctatt
    42001 ttgcttgcga ttcccttggc tgtttttctt cgctatcatg agaagctggc cgactgggtc
    42061 ttgcagattg caggtatttt ccagaccatc ccgtctctgg ccttgttggg gctctttatc
    42121 cctttgatgg gaattgggac cttgccggct ttgacagctc tagtgattta tgcgattttt
    42181 ccgattttac aaaatactat tactgggctg aagggaattg atccgagtct tcaagaggct
    42241 gggattgcct ttgggatgac cagatgggag cgtctcaaga agtttgaaat tccacttgcc
    42301 atgcctgtta tcatgtctgg aattcggacg gcagcggtct tgattatcgg tacggctacc
    42361 ttggcgacct tgattggggc agggggactg ggttccttta tcctgttggg aattgaccgt
    42421 aataatgcca gtttgatttt gattggggcc ctttcttctg cagtgctagc tattgccttt
    42481 aacttcctac taaaagtaat ggaaaaagcg aaattgcgga cgattttctc tggttttgcc
    42541 ttggtggctt tattactggg tctgtcttat agtccagccc ttttggctca aaaagagaag
    42601 gaaaacttga ttattgctgg gaaaataggc ccagaaccag aaattttggc taatatgtat
    42661 aaattgctga ttgaagaaaa taccagcatg actgcgactg ttaaaccgaa ttttgggacg
    42721 acaagtttcc tttatgaagc tctgaaaaaa ggtgatattg acatttatcc tgaatttacc
    42781 ggtacggtga ctgaaagttt gcttcaacca tcacccaagg tgagtcatga gccagagcag
    42841 gtttatcaag tggcgcgtga tggcattgcc aagcaggatc atctagccta tctcaaacct
    42901 atgtcttatc aaaataccta tgctgtagct gttccgaaaa agattgctca agaatatggc
    42961 ttgaagacca tttcggattt gaaaaaagtg gaagggcagc tgaaggcagg ctttacgctt
    43021 gagtttaacg accgtgaaga tggaaataag ggcttgcaat caatgtatgg tctcaatctc
    43081 aatgtggcga ctatgcagcc agctcttcgt tatcaggcaa ttcagtcagg ggatattcaa
    43141 atcacggatg cctattcgac tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa
    43201 gatgacaagc aactcttccc accttatcaa ggggctccac tcatgaaaga agctcttctc
    43261 aagaaacacc cagagttgga aagagttctt aatacattgg ctggtaagat tacagaaagc
    43321 cagatgagcc agctcaacta ccaagtcggt gttgaaggca agtcagcaaa gcaagtagcc
    43381 aaggagtttc tccaagaaca aggtttgttg aagaaatgat gggacagaga ctt
//
LOCUS       DAVBOM010000011        42860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBOM010000011 DAVBOM010000000
VERSION     DAVBOM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.011"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ878_000652"
     CDS             complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ878_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET3095035.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ878_000653"
     CDS             complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ878_000653"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET3095036.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ878_000654"
     CDS             complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ878_000654"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET3095037.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3795..5063)
                     /locus_tag="VQ878_000655"
     CDS             complement(3795..5063)
                     /locus_tag="VQ878_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET3095038.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5183..5551)
                     /locus_tag="VQ878_000656"
     CDS             complement(5183..5551)
                     /locus_tag="VQ878_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET3095039.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5544..5810)
                     /locus_tag="VQ878_000657"
     CDS             complement(5544..5810)
                     /locus_tag="VQ878_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET3095040.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ878_000658"
     CDS             complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ878_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET3095041.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9378..9947)
                     /locus_tag="VQ878_000659"
     CDS             complement(9378..9947)
                     /locus_tag="VQ878_000659"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET3095042.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ878_000660"
     CDS             complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ878_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET3095043.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11217..11411)
                     /locus_tag="VQ878_000661"
     CDS             complement(11217..11411)
                     /locus_tag="VQ878_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET3095044.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ878_000662"
     CDS             complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ878_000662"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET3095045.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ878_000663"
     CDS             complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ878_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET3095046.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAEVIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14345..15103)
                     /locus_tag="VQ878_000664"
     CDS             complement(14345..15103)
                     /locus_tag="VQ878_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET3095047.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15161..16342)
                     /locus_tag="VQ878_000665"
     CDS             complement(15161..16342)
                     /locus_tag="VQ878_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3095048.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ878_000666"
     CDS             16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ878_000666"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET3095049.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17048..17121
                     /locus_tag="VQ878_000667"
     tRNA            17048..17121
                     /locus_tag="VQ878_000667"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17082..17084,aa:Arg,seq:tct)
     gene            17286..17411
                     /gene="comC"
                     /locus_tag="VQ878_000668"
     CDS             17286..17411
                     /gene="comC"
                     /locus_tag="VQ878_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET3095050.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17432..18757
                     /locus_tag="VQ878_000669"
     CDS             17432..18757
                     /locus_tag="VQ878_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3095051.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18754..19506
                     /locus_tag="VQ878_000670"
     CDS             18754..19506
                     /locus_tag="VQ878_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3095052.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19558..19629
                     /locus_tag="VQ878_000671"
     tRNA            19558..19629
                     /locus_tag="VQ878_000671"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19591..19593,aa:Glu,seq:ttc)
     gene            19635..19708
                     /locus_tag="VQ878_000672"
     tRNA            19635..19708
                     /locus_tag="VQ878_000672"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19669..19671,aa:Asn,seq:gtt)
     gene            complement(19749..20291)
                     /locus_tag="VQ878_000673"
     CDS             complement(19749..20291)
                     /locus_tag="VQ878_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET3095053.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20470..21237
                     /locus_tag="VQ878_000674"
     CDS             20470..21237
                     /locus_tag="VQ878_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET3095054.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21241..21660
                     /locus_tag="VQ878_000675"
                     /pseudo
     CDS             21241..21660
                     /locus_tag="VQ878_000675"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21688..22002
                     /locus_tag="VQ878_000676"
     CDS             21688..22002
                     /locus_tag="VQ878_000676"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET3095055.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22103..24655)
                     /locus_tag="VQ878_000677"
     CDS             complement(22103..24655)
                     /locus_tag="VQ878_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET3095056.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILFTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24717..26339)
                     /locus_tag="VQ878_000678"
     CDS             complement(24717..26339)
                     /locus_tag="VQ878_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3095057.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26545..27570
                     /gene="trpS"
                     /locus_tag="VQ878_000679"
     CDS             26545..27570
                     /gene="trpS"
                     /locus_tag="VQ878_000679"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET3095058.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27722..29200
                     /gene="guaB"
                     /locus_tag="VQ878_000680"
     CDS             27722..29200
                     /gene="guaB"
                     /locus_tag="VQ878_000680"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET3095059.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ878_000681"
     CDS             complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ878_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET3095060.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ878_000682"
     CDS             complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ878_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET3095061.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30878..32128
                     /locus_tag="VQ878_000683"
     CDS             30878..32128
                     /locus_tag="VQ878_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3095062.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAELEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32125..33408
                     /locus_tag="VQ878_000684"
     CDS             32125..33408
                     /locus_tag="VQ878_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3095063.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33450..34271
                     /locus_tag="VQ878_000685"
     CDS             33450..34271
                     /locus_tag="VQ878_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3095064.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ878_000686"
     CDS             34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ878_000686"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET3095065.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34824..35651
                     /locus_tag="VQ878_000687"
     CDS             34824..35651
                     /locus_tag="VQ878_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3095066.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35636..36475
                     /locus_tag="VQ878_000688"
     CDS             35636..36475
                     /locus_tag="VQ878_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3095067.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36468..37262
                     /locus_tag="VQ878_000689"
     CDS             36468..37262
                     /locus_tag="VQ878_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3095068.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37321..38139
                     /gene="mreC"
                     /locus_tag="VQ878_000690"
     CDS             37321..38139
                     /gene="mreC"
                     /locus_tag="VQ878_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET3095069.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38139..38633
                     /gene="mreD"
                     /locus_tag="VQ878_000691"
     CDS             38139..38633
                     /gene="mreD"
                     /locus_tag="VQ878_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET3095070.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38727..39905
                     /locus_tag="VQ878_000692"
     CDS             38727..39905
                     /locus_tag="VQ878_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3095071.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ878_000693"
     CDS             40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ878_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET3095072.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40987..42027
                     /locus_tag="VQ878_000694"
     CDS             40987..42027
                     /locus_tag="VQ878_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET3095073.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ878_000695"
     CDS             42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ878_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3095074.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(42751..>42860)
                     /locus_tag="VQ878_000696"
     CDS             complement(42751..>42860)
                     /locus_tag="VQ878_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3095075.1"
                     /translation="NKAFRTLEDVIQGLEKEVIKSIVNRRRTRMLFESR"
BASE COUNT        13428 a         7397 c         7893 g        14142 t
ORIGIN      
        1 ttatttttcg tcattcattt ttgactttac ttcatcatag gatagtgcat gagattcctc
       61 ttctactgct tcaggcatct ttcctgtttc gtaaagagct ttaatttgtg tactatccaa
      121 tgtttcgtat ttcaataatg cttctgcaat taacttgtga atttcacgat ttgactgaat
      181 aatttcagca gctttatttc gtgcctcatt taataatgaa cgaacctctt catcaatttc
      241 ataagctgtt tgttctgaaa ttgatttttg aggactctgt gcaccaaaca tagcatggtt
      301 tccttcatat tgtactgggc caagtttttc actcataccg tactctgtaa ccattgcacg
      361 cgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct gtagtttgga cattaaagat
      421 aatttcttca gctacacgtc cacccattaa gccagccaat tgctctttca tatcttcttt
      481 agatagaagc atttgatcct ctttaggaag tgcaatcatg tatccgcctg cacggccgcg
      541 tggtacaatt gtaaccttat ggacaacgcg agcattcgac aagactagac caacaatggt
      601 atgtcctgcc tcatggtaag caaccaattc tcgttctttt tgtgaaactg tcttatcttt
      661 cttagaaggt ccagcaataa ctctatcttc tgcttcatca atatctgaag catcaattat
      721 cgatttattg cgacgagcag caactaaagc tgcttcattc aagacattct ctaaatcagc
      781 accaacaaag cctggagttt gttgagccac taatttcaaa tcaacatctt ctgctaaagg
      841 cttgttctta gcgtgaactt tcaagattgc ttcacgacct ttaacatcag gacgaccaac
      901 caatactttt ctatcaaaac gtcctggacg caaaagggca ggatcaagta catctgaacg
      961 gtttgtcgca gcgatgacga taatcccttc atttccctca aaaccatcca tctcaatcaa
     1021 aagttggttc aaggtttgtt cacgttcgtc attacctccg ccgagaccga ctccacgttg
     1081 acgtccaaca gcatcaattt catcgataaa gatgatagct ggtgctgctt ttttggcatc
     1141 ctcaaaaaga gagcgaacac gactagctcc aactccgaca aacatttcta caaagtcaga
     1201 acctgagata ctaaagaatg gaacacctgc ttctccagcg actgccttag caagcaaagt
     1261 tttacctgtc cccggaggtc cctccaaaag aacacctgct ggaatacggg ctccaagttt
     1321 tgtgaatcgt tttggatctt ttaagaactc aacaacttca actagttctt gtttttcttc
     1381 ctcagctcca gcaacatctg aaaatcttac tttaatatct tctttatttg ctgctttagc
     1441 cttactacgt ccaaaactca ttggattacg gccattgcct cctcccatat ttcccatcat
     1501 agagaatagg aagaagaata gaattccaaa tggcacaatg gatacgagta gattaatcca
     1561 tataccactt gaactttcat gcttaacagt tacttctgct ttatggtcag tagcaagttt
     1621 ttgcaattct gatacggtag tatctgcagg aagaatagtg ctggtaaatt tctctacctt
     1681 agtaacagat ggcgtgaaaa actgaatacc tgtttcttct ttacttgttt taggattttt
     1741 atagacacca gaaacttcga taacactacc atttggttgg taagttaatt cttttacatt
     1801 accatcggta atttcttgta ccaactcagt atagttgatt tgctgacttc ctcctgagtt
     1861 attcccagaa tagaaatact ggaatcctgt cacaaggaaa aagataaata ataaccatag
     1921 aaaaggattt ttaattaaac cattattttg ttttttcatt aaagattatt ctttctaatt
     1981 tgaatacact tcctctttca atactccaat ataaggaaga ttacgataat tttctttgta
     2041 gtctaaacca taacctacta caaactcatt tgggatagta aagcaggtat agtctgcctc
     2101 aatttctaca acacgtcctt ctggtttatc caacaaggtt gcaattttaa cagaagctgc
     2161 ttctcttgct ttaaacatat ctcgcaaatt cttcaaagtt tgacctgtat caatgatatc
     2221 ttctacaaat agaacatgtc ttcctttgat atcttgagtc acatcttgtt taatattgat
     2281 aacaccacta cttgctgttc caccatggta gctagaaacc atcatgaagt ccatttcaat
     2341 atgtgtatca atatgtttga ccaattcagc cataaaagga atagatcctt ttaaaatccc
     2401 aactaagatt ggattttttc ctgcatagtc tttagttaat tgagcaccta gttttttagc
     2461 tgcttctgta atttcatcgt gtgaaacgag gactttttta atatcgtttt ctaacatttt
     2521 ttacctatct attttttcta tataaagtac agtgttcatt atatcatttt tcgttttttt
     2581 actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt tcaccaaatt gctcaataat
     2641 aagagcagag tttctctttt ccatagggat tttcaaatca ataaataaac gtctgagttt
     2701 ttttctatgc ccattttgaa tcaaaacatc tcctgttttt cgatgacgaa tgtgtatgga
     2761 tgtttcacgt gaaacaggta tttgttgaat tgattcacct tctaatggaa gtccaaagga
     2821 aaataaatat ccttgataag ctacctgatt ttgatagtgt aacacaagtt catcttcctc
     2881 ttcatcagcc tgcggactga ttttacaaat ctgaaactgt tggtactctt ttatcaattc
     2941 atagccattt ttaatcggat gacgatactg gcttttagat tttaaaatct gctgaacttc
     3001 agcaaactga gcttttgtaa gattcaaatc tggaaaacga ttcagataag tttgaagtaa
     3061 aactctttgt gtagactcag agtaagaaaa taactgctgt aaatcttcca cattaatatt
     3121 gttagataat tcagctattg ccaaatcata atctaaaatt tcattgccaa tgcctaagat
     3181 tgcatcccta aatcgaggat tttctttttc caattctggt aagtaagagt ttcgaatacg
     3241 atttcgaaaa taatgattct cctgatttga tgtatcttca aagtgaaaaa ttgatggaaa
     3301 gtcttttttc tgaaaatgca agaagggacg aatgatttct atctctccga ctacttgctt
     3361 ctccttaatt cctgatagat agcgcaagcg agttcctcga atcaagcgca tcaaaatcgt
     3421 ttccacctga tcatcagcat ggtgggcagt gactaaagct gtcgcacctg tctttttcat
     3481 gacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc gcttctgaaa attctcctga
     3541 aaaattgctg atataaatag gaagctctgc ttcagcagcc aacttcctta attccttttc
     3601 ttcccaatct gattcaattc tctgcttatg attcacatga gctagaatca attcaatctc
     3661 taactctttt tgataagtag acaatacctt aaatagaaac atggaatcta atccaccaga
     3721 aagagctaga accgccttag catgcttttt gaaatatccc ttcttgagaa aatgatttaa
     3781 aaaatctggt tccctcattt tagaacctca taaacatcct tggctatctt agaaatcgta
     3841 tcataatcag aattcttagt gaaaatagaa agaataaatg gagaatctgc atagacaaca
     3901 cccgtatcat gcttaaattc atccgcatct ccaattttat gagctacttt aacagaaaca
     3961 cctttggcaa ttcgctgact atcaaaatct gttttagtca aagactctaa cacaaatcca
     4021 ttttgattat aaatagcttc cataaacttc ccggccatct tagaagaaat caatttttct
     4081 tttggatccc aatcatctcc cataatggca gacatcttgg atttgaatgt ggcatcagat
     4141 tggtttgaaa tgtaatatcc caatagatta tgagctacat tatcagattc ttttgatact
     4201 ttcgtaatta aatcctttaa agaatattct ttattatctt cttttttagg aagactacca
     4261 cttccctctg gtttataaga acctggaaaa tcattgactg cagatacgta ttttacagtc
     4321 gtatctaact gataaagacc ctcatttatt ttttcttgcg tataatagag ataagagagt
     4381 ttcaaaacgc tggctgcata catcttttca tcttgattga taccagcttc ttttccagta
     4441 gtcagttgct taacataaat agagaaagaa tctttctgat atttttcaga taacatttct
     4501 tgaactttac tcatccgatt atcttcttca gaagttgatt ctttagctac ccatccagcc
     4561 tgatcaatat gtagaaattc tcttccttct acaaacatgg tcttgtcgat tgatacttgc
     4621 gaataagctg ataaggatga tttcacttct tttaaatcat aaggactatt gtacagttta
     4681 aagtcagatt ctaaccatgc tttttttatt gttggagtta cctctgattg atcatataaa
     4741 aatcgtttgt ccgcagctat aaattgatga tttgatagct taaatactgg aattccttgt
     4801 ttatttaagc gccactcggt tatttgaaaa cttgttttgg gagtcaattt cccagattcc
     4861 actactaaat cttcattcgc ataaacagga acctctccat aaaccatggg agaacttaat
     4921 ttttctctaa aataaatacc aaagtcagat tgtgaaaggt aataaatttc tttcgaagta
     4981 tagacgactt ctttttctgt actaacgact tttgaaatgg tcaaaaaact tggtagcaac
     5041 aaaataatta agaatttacg cattcttcct ttccttttct tcttgtaaac gcaataattg
     5101 atttttatca gccaattctt ccagcttttc atctgacaaa ctcaaaaatt gctctattac
     5161 gtctaataaa ttttccattt tatcaccttt gaagcaagtc aggaatcgta taaacttttt
     5221 ccctcgactt agaataatag tacttcgctc gtgtatattt ggcagcataa tcttcatctt
     5281 tcaacttggt agcaaatgct gtctccttat ccttttcatc actcaaagtt tgatactgag
     5341 tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg ctgataactc tgcgctaaat
     5401 taaaagttgg caagataaat aatagcataa tcaaaatcaa tacccctccc ataaaacgat
     5461 tccgtttttg tcgttctttc atcaggtagc gacgacgttg gtattcattt tgaataaaag
     5521 aattattcaa ttgtacaata tttttagaca ttttcttcta cccgtgtttc actgataatt
     5581 tcatacattc ctgctgcatc ttcttttttt gtactatctt tcatctctag tacttttaca
     5641 agcagcaact tattgccaaa gcgaatttca acttggtcat taactttcaa gtccgttgaa
     5701 cttttggcca agattccatt aaccttgatt ctacctttat ctgctacttc ctttgcgact
     5761 gtacgacgct tgataattcg cgatactttt aaatatttat ctaatctcat ccttattacc
     5821 tcaatttatt attgtaccat ttttatctat tttatagaag aaaaatatca aatggaattt
     5881 tcttccttag actcttttat ctctaataaa ctttctccaa aaatcagcag accttctaaa
     5941 atttcataat ctttcttatt ttggacatca aatacaagct ccattaatcc cttattctca
     6001 gcgatgcctg cttttaagtt cgttacggat aaagctttaa aataatcttg agctaaaaac
     6061 aatcgttgag tgactttttc aaattgaatt gtaattttat tatcttttct ttccacacgt
     6121 tgaacaaaga ccttgtccaa gtatgattta accaaaccaa tctctaaaag ataggctact
     6181 acatctgggt attctccaaa acggtctatc aactcctctt gtaactcttc ataattgaca
     6241 cggttgtcaa tttgacgaat tttcttgtaa atttcaatct tatgtcgttg atcagaaata
     6301 taagtatcag gaagataggc atcaatttgc aaaatcaact cagcattccc tttggttctt
     6361 gtgttagcgt tagcattacc gtttcgttta gcaatagctt cctctaataa ctgcgaatac
     6421 aattcaaaac caacagaatc aatgaaacca gactgggatt ttcctaaaag atttcctgct
     6481 ccacgaatcg aaagatctcg cattgcaatc ttaaagccag agcccaattc tgtaaatcct
     6541 ttaatcgctt ctaatctctt ttcagagact tcactgattg atttttctgg acgatacatg
     6601 agataagcat aagcaatacg attactacga ccgactcttc ctcttaactg atataaggtt
     6661 gacaagccca tatggtccgc attttcaata aataaagtat tagcatttgg aatgtccacc
     6721 cctgtctcaa taatagtagt cgtcaccaag atatcgtatt gtccctcaat aaagtctaat
     6781 agagtatttt ccaactggac ttcactcatt cgaccatgaa catatccaat cgaagcctct
     6841 ggaatcaact cctgtaattc tgaaaccttc tgaacaattg tatcaacttt gttgtaaaga
     6901 taataaactt gacctccacg ctccatttca cgcaagacag catcacgaat gacactatca
     6961 ttcttttcca aaacataggt ctgaacagga tagcgattag tcggcggagt ttcaataaca
     7021 gacaaatctc tgattcccag catagacata tggagggtac gagggattgg cgtagcggtc
     7081 aaggttagga catccacttg tttcttcagt tctttcaaag tttccttatg cttgacacca
     7141 aatcgctgtt cctcatcaat aatcatcaag cccaaatcag caaacacaac atcttttgac
     7201 aaaacacgat gtgttccaat caaaatatcg acttgaccgt ttttcaattt ttcaagtgtt
     7261 gcagtctgct cttttttact tctaaagcga ctcaacacat caacattaac tgcaaaattt
     7321 tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta aaaccgtcgt cggaactaga
     7381 atgacaacct gtttgtgatc attgactgct ttaaaggctg cacgcatagc aacttcagtc
     7441 tttccaaaac caacatcccc aactaaaagt ctatccattg gctgagaagc ctgcatatcc
     7501 ctcttgattt cctcaatact acgaagttgg tcatccgttt caacataagg gaaagcatca
     7561 tcaaaggcat cttgatcatc atcatcagct gagaaagcaa aacccttcaa ctgactacgt
     7621 tcagagtaga gtttgattaa atcatcagct atatcctcta cctggttctt aaccttttgc
     7681 ttggcctttt taaaatgacc gtcatttaat ttattgagtt ttggagcttt accatcactt
     7741 gaaatatatt tggacagtag atgaatctgt tccacgggaa tagaaatttg atcaccattt
     7801 tggtattgga cactgacata atcacgatga attcccttga tttcaatggt ttcaattcct
     7861 agatattgac caatcccatg gatatgatgg acaacatagt cccctttttc aagttcattg
     7921 taatctttta atctctctgc atttgaaaca tgttgtcttc gaaaacgacg ctttaatttc
     7981 ttttgaaaaa tctcatgttc agttatcaat aaaatctttt catctacaaa atgaaaacca
     8041 tgtctgagat taccttctat taagtttaca gattctttac agatacttgt cttatctcta
     8101 gaatccaatt taatctgata ttcctctaac atatcctcca atgttttact tcccattgaa
     8161 ttgctagact gcagaataat ggtgtaatcc atttttttat atcgttcaat ttcttctttt
     8221 agaaaagaaa actgattgaa aaattcctgc ataggatatt gattgaattg ataaattttg
     8281 tcaaatttga gatttcctaa acccttttga agattagaga aaaaggtcac tggactttgt
     8341 tttttataga tttgttcaat atcagaaaaa tactgcatat cagaaaatgc tttactattc
     8401 tgtaattctt ctgtaaagta ctgcgctaat tctctttcaa agacttcata ctgattcatc
     8461 aatttttgat aatcatcaaa gaatattgga gtatcttttt caatataatc aaagacagtc
     8521 catgtcttat catagcacaa agataaaaac ttccgagaat ctgcatgact ttgcttttga
     8581 tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa taggtgataa agtttttgaa
     8641 atttgttttt ctaaagctga ctgtcctcgt tgataatcct tttctctcaa aagcatatca
     8701 ctagctggaa agatagtgag ttctgtctta ttttctttcg ataattgtgt ttctacttca
     8761 aatgacctga taccatcaat ttcatcacca aaaaactcaa ttcgacaagg ttctaactgg
     8821 gatatttcaa aaatatctaa aatatctcct cgaagactaa attcaccctg agtttgtact
     8881 tgagtaactt ttcgatagcc attttccttt aactgatgga taaacgcgtg ttgagcatat
     8941 tcttcaccaa ctgagatttt tacaatacta tctttgaatg cattgggaga cggtaaaatc
     9001 aatcgacttg ctgcgatatt acaaactaaa atccctttct tagatgaatc agtcaaaaaa
     9061 cgcaaggctt caacccgtga aataattttt tcctgtgaag acatcaaaaa ctccaccata
     9121 ggagcatcat ctaccaaaaa tggatagacg agttcctcac ccaagataga aataagatca
     9181 ctaacaagtc cttctgcttc tccataagtt gacgtcaata acacaatcct atcttctttt
     9241 tctaaactgc ttgcaattgc aagagcctta gtagatgttg ataaaccaag tattagttgt
     9301 cttttcttat ctgttaaatt ttgatgccat tttttaatct gatcattttc tgagaataaa
     9361 tctaataagg tcaccattta tccgttatac ctctgcattg ttttctcaaa atttttctct
     9421 tgtaaatagt agtttacaga atcgtcaact ttgtcaacag actgtaaaat accgatataa
     9481 tcatccctgt caaacttact caaaacatga tgaacaactg acataccatt tttaggtctt
     9541 ccaattccaa tcttaacacg gttaaagacc tgagttccta tatgttgaat aatagacttg
     9601 ataccattat gaccacctgc tgagcctttt gctcttaaac gaattttccc aacttccatg
     9661 tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca aaccatagta agttaataaa
     9721 gcatgaactg cttttccact ttcattcata aaggtcgttg gtttaaccag ataaattttt
     9781 tctccattta ggaaaaagga tgctaggtca gcttgaaata tcttatcgtg tgtaaaagtg
     9841 acattctgtt tcttcgctag ttgatcaatc aacataaaac caacattgtg ttttgtttca
     9901 aaatatttat cccctggatt tcccaagcct acaagtaatt tggtcattta tttttccttt
     9961 caaaagccaa aagggttgga atttttttcc aacctaattg acaccattta ttaattttta
    10021 gacattaaag cggaattcca tgatatcgcc atcttgaacg atatattctt ttccttcttc
    10081 acgcaagcgt ccagcttctt ttacggcctt ttcagatccg tatttcacta gatcttcata
    10141 tgacatggtt actgcacgaa taaagccttt ttcaaagtct gagtggataa taccagctgc
    10201 ttgaggagcc ttcataccac gtttgaaagt ccaagcgcga acttcttttt caccagctgt
    10261 gaagtaagtt cccaatccaa gcaagtggta agctgcacgc gtcaacttat ctacacctga
    10321 ttctgtcaaa ccaatggctt caagaaactc ttttttatct tcatcatcca attcagaaat
    10381 ttcttcctca gcacgcgcag aaataacgac tacttcagca ttttctgtcg ctgcaaattc
    10441 acgaatttgt ttgacatagt cgatagagtc aggttccgaa accacatcct catccacatt
    10501 agctacataa agaactggtt tagtcgtcaa aaggaaaaga cctttgacaa ccttttgttc
    10561 ctcatctgta aattcaatgg tacgagctga tttcccatct tctaggactg gtttaatctt
    10621 ttgaagaaca ttgaattctg ctactgattc tttatctttt tgcgtacgtg ccatcttttc
    10681 tacacgcgca tatcgtttgt tcactgattc taagtcagca agaatcaatt ccagattaat
    10741 ggtatcaata tctgcaagcg gatctacaaa ggcgtcttca cgtccttgct cgcgcatcac
    10801 attttcatca tcaaaagcac gaactacgtg aacaatcgca tctacttcac gaatattggc
    10861 caagaattta ttccctagcc cctctccttt tgaagctcct tttacaatcc ctgcaatatc
    10921 tgtaaattca aatgttgtgg gaactgtctt tttaggagtt atcatttcag ttagtttttg
    10981 tagacgttca tctggaactt ccaccattcc aacatttgga tcaatcgtcg caaatgggta
    11041 gtttgctgcc tctgctcctg cttttgtaat tgcattaaat agtgttgatt taccaacgtt
    11101 tggcaaacca acgatacctg ctgtcaaagc catatttctc attctccgtt ttcatttcaa
    11161 tccctaatat tataacacaa aaagggataa agtgctaacc ctctaactaa gggttctcag
    11221 tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca
    11281 caattactgc attttatttt gatatctgct cctacacgtg taatttccca acgattagcc
    11341 tttttaccag tcgacttgat tgtacaagcg tgtggttttt tcatctcaac aaaatttcca
    11401 acttgataca tactactctc cttttctttt tcgattatat cataaaagag gcgagccagg
    11461 ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc
    11521 agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa tggtcacctt
    11581 ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac taatggtcaa
    11641 atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa cttctggaga
    11701 gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac cattttgagt
    11761 cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca cattaaaagt
    11821 aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt ttccttctag
    11881 gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat tggcaaagaa
    11941 aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta gagaacggct
    12001 aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt tctggcttag
    12061 gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata cgaagtggac
    12121 acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt cattaataat
    12181 tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt cttggattcg
    12241 tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac tggttaaaac
    12301 aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac tagatactac
    12361 attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatca acaaaccagc
    12421 atcttcattt ttttgagaaa taaaattttc aattgagatt tgaccatttg aaccaattaa
    12481 agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa tggcattttt
    12541 agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt tattaattga
    12601 aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa tagtaataat
    12661 agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt cctatcaagt tttttagctt
    12721 gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa ttatttgatt
    12781 ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat caaagatttt
    12841 attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc cttcccaatt
    12901 tttggaagac tattatctgt tagttctcta gataaataca tggctacttg acgggccaaa
    12961 acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc ataaaagtta
    13021 ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac atcttgtttg
    13081 cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt ttttactctg
    13141 gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga atcaaattgc
    13201 ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc cgttttactt
    13261 tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt caatccccaa
    13321 ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact acgatcactc
    13381 gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa aaattcttcc
    13441 tgagttgcga ctttttttcc gctgagtgac tggatatcat cgattaacaa aagatcaaga
    13501 ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc aagaaagtca
    13561 ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt ttttagaatt
    13621 tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc atagataaaa
    13681 agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga tacagcccaa
    13741 acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa tcccgtatct
    13801 gaataaggaa tagatactaa ctttggacta tagtcataaa gagttaaatt tgtagcttct
    13861 tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg agttatttca
    13921 gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt ttcccagacc
    13981 atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac cttgataact
    14041 tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg tgcaaattct
    14101 aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac tatttaaaag
    14161 tttaatacta gagatatttt accatagata gcaagaattt tccacaagct gtgaaaaata
    14221 atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa ttattgattt
    14281 attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa ataaaagaac
    14341 agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa aaagaaataa
    14401 tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg agtagttttc
    14461 ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc ttttgttttt
    14521 tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata atccgttgaa
    14581 agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg gcttgtgata
    14641 gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa cgaatggagt
    14701 tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt
    14761 tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt tctctctgta
    14821 aattttcaat aatggactgg accatcatct cttggtctga aatctgttta acaacagctg
    14881 ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct gcaaggattt
    14941 cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca ttttctttga
    15001 tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt tgatagggat
    15061 ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta cactaacaca
    15121 tcttttctct tatgtaaagc tttctttaca tagatgtcaa ttaagattct aaatcacctg
    15181 aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag taggttatct
    15241 taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt gatgaagcaa
    15301 tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca ttggcaggca
    15361 tattactttg taccgaacga acaattacac cagatgtaac attacttgga atattgagtc
    15421 ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc aaagctggac
    15481 gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca tttgcaggaa
    15541 ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta cttgaggtaa
    15601 ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct gggttaatag
    15661 cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat tttaaggata
    15721 catttctatt gagactggat acgatacctt gagtgacagt atttgcatat tcagaaccta
    15781 acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa tcaccaaact
    15841 cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca gagaaagtgt
    15901 cagctccgac aatttttcca ggtactttag tcccatctga caatcgaata tctactttgc
    15961 tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca ttctttttat
    16021 aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta tcatcattgc
    16081 caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca gcatctttta
    16141 ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt gtaatagtac
    16201 tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt gaaaaactac
    16261 ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac cattttttgt
    16321 aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga aagtataaac
    16381 tgactagctt aattataact taaacacaaa agttttacac aaactgtgga taactctttt
    16441 gaaattgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa
    16501 tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg gaaactgaaa
    16561 gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag atttgctaag
    16621 tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga atcagaaaat
    16681 caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga ccgtgatttc
    16741 gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag taagcagtta
    16801 gaagaaactt ctataaaagg attttctact cttactttta ttattggggg aagtttagga
    16861 ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg cctaacctta
    16921 ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt tacgattcag
    16981 cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg gtagaataat
    17041 tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag
    17101 gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg gcttttttct
    17161 taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc taaaacgaaa
    17221 ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt ttaggagatt
    17281 ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa aaagacttac
    17341 aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt attttacaaa
    17401 gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg ggacggttat
    17461 tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc aaataaatag
    17521 aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat ttgattttcc
    17581 cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc ctttgggatt
    17641 atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat tcctaagttt
    17701 actactatct cttttatatg agagcactca taactttctg tccgtaactt tctcctctat
    17761 aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg tgacggtgtt
    17821 aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag cctattttga
    17881 tgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat tgctacatat
    17941 tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt ttggaagtat
    18001 tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga attctcataa
    18061 agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga aacatttaca
    18121 gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc gacatgatta
    18181 tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac aggaaattga
    18241 cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag ataagtacac
    18301 ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg ctcagtcaat
    18361 tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata cgattaccaa
    18421 gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga ataatgctgt
    18481 cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta agatggaaac
    18541 tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt caggagatct
    18601 atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa ataatgtgaa
    18661 agaactacta gataagtaca acaatattat tttagaaaca gagatggaag gcagtacatt
    18721 tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt agaagatgtt
    18781 attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga atcgaatatt
    18841 ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat tgaaaatgat
    18901 gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa aaagggattt
    18961 gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt tatcactagt
    19021 cgatcagagt ttgcgactct aacatataaa taccaggtat cagccctaga ttttgttgat
    19081 aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt ctacacgaag
    19141 agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta caagggaaat
    19201 gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt atctcataaa
    19261 ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac agatattcag
    19321 gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt ggtaaatata
    19381 ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga agaccatcgt
    19441 tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa aaaatctcaa
    19501 aagtgattga caattagcaa gaaattgata taatggttat atctgctaca gatagaaggt
    19561 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    19621 tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat
    19681 gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc tgtgttcctc
    19741 tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat ttcttgagaa
    19801 ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc atgagttaga
    19861 tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa tcgcttttgt
    19921 aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat ttctttagtc
    19981 ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc aaaaacttct
    20041 aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa tgtatggaat
    20101 agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt atagaagctg
    20161 gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc aaatggctgt
    20221 tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa gcgtttgtta
    20281 ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa atagattttt
    20341 tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt agacaatatg
    20401 tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa accaaccttt
    20461 attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat atttttgtca
    20521 tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt aaataatgat
    20581 aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt gtccaattta
    20641 aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg
    20701 gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga aaaaacaact
    20761 acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact
    20821 gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt
    20881 gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca atcttctaat
    20941 ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac ttctttgata
    21001 ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt agttcctgcc
    21061 agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag
    21121 ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga taaactagtt
    21181 tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt tggttaatta
    21241 caatcaggat ctgggcaatt agcagacaaa tccagtcagt tactttcagg tgcttctcca
    21301 ttagagaata gagctaataa attggcagat ggatctagga aactagcaga aggtggaaca
    21361 aagttaactt ctggattgga agatttacag acaggacttg cttctttagg acaaggacta
    21421 ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc agagattttg
    21481 tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa tggaatcgca
    21541 atagctcctt atatgatatc agttgctctt ttttttgcag caatatcaac aaatatgata
    21601 tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt gaaatcttga
    21661 gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg aggagttcag
    21721 cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat cctaacaagt
    21781 ttagtattca tgtctatggt gaccacttta gcaacgtgga atagccgtat aggagctttt
    21841 ttctcactta ttttgctttt actacagtta gcatcaagtg caggtactta tccacttgct
    21901 ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta ttcagtttcg
    21961 ggattacgac aaacaatctc tatcaacaag tcattttcct agctgtcata ctagctctat
    22021 ttactggttt aggtatgcta gcctatcaac ataagaaaat ggaagaagat taaaaaaatc
    22081 gaccgattaa ctggtcgatt ttttatgcct tagatgactt tcgtctgtga ttatagattc
    22141 caaatagtaa gagagaagta aaggaacaga ttgctccagt aataaaacca ttgggaatga
    22201 aggaaagtgt aatagttcct ttccccttgg gaatgtcaac tttcataaat ccagtttgag
    22261 cttgtttaat ttctattttc ttaccatctt ggtaggcaga ccaacctttg tcataaggaa
    22321 tggtgaagaa aatagatgta tcttgttgga catcatatgt agcaaaaacc ttgtttttag
    22381 aagttgatac tgtgacaggt tgttctttaa ttttttgaat tgcctcggtg aaagttttgg
    22441 tatctaaacg atagaaggta ggagattcaa atgatacttg tgaatttcca gggaaactaa
    22501 cattgatatt gaaagttttt ttctctttag tatatcctag attaaagaag gagaagacat
    22561 tatcagttgt aaaagtcttt ttttcaccat ttacaaggat gtcaaccttc ttttgtttat
    22621 cgttagaaaa gtgaaggttt atgaaagaga gataaacttg gctgttttct ggaacttcaa
    22681 tttgatactg gattgctgca tcttcatttg aagaacttgt gacactaatc aaatcattag
    22741 tattttctat tttttctgtt ttttcataag gtattggaga aaaataatca aaattgacgt
    22801 tagcaagttg atttaaaaat gaggcctgat tatccaaggt atgttcattg aacttgacat
    22861 cattgtaaac agattgacta gcaactgcaa tcggaagaga gtattgattt tcatataggg
    22921 taagattatc tttttgatag atatctttaa agccatactt atcaatagga ctgtctgaga
    22981 tattgtactg gataccaaat aaactatcag ccaaaatact attatttgca tatcggagat
    23041 tgagattagt cccagaggat ttaaaaccaa gtttatctaa agtagagctt gatgaacgat
    23101 ttcgaacaga tgaaaattga gagattccat tgtagttgaa tttcatactg tcatttcctg
    23161 tctgagtttg tagtttttca gtacgagtaa attgatttcc aatatatgtt gagaaagatt
    23221 ccatagctag gatatctcga ctataagcac ttcgagaagc aaatccccat tccttagcaa
    23281 ttccgtccat ttgagatgaa gcatttaaac tcatttcaac cagtataaat aaagagatta
    23341 gaatggcaaa tagattcaca gatataaact ttttgataac tgcaaggagt aaaagagaat
    23401 agacaaccaa aaattcaaga gtaaacagaa tattcaaatc tgttaaaaaa gaataatgcg
    23461 attttagata gatggtagct aaaaatcctg ctactacaag aaaaagcgaa actaaaaaat
    23521 tccagacttt aagttctttc agacgcttta agacttctgc tgctgtgtaa attaacaagg
    23581 tagagaaaat ccaagcatag cgatgtaaaa acatgtttgg agtatgcatg ccttgccaaa
    23641 ataagtcaag agcttctatg taaaagcttg caattagaaa tgcaaagaat attacatata
    23701 tgagtttcac gtgaaactta atagatttca gcgtaaaaaa taaaatggtc aaaataaagg
    23761 gaaatagtcc aacaaaaatc attgggatgg ccccatactt tgttgtgtca aaggaaccaa
    23821 tgaattgctt agcaaagaga tcaagatacc agctactttc agtttgaaac tttgtaactt
    23881 cagtcaattt ttccccatgt gtctgtaaat caaatagagt gggaagagtc ataatcaaac
    23941 tagccatacc agctaaaaag gagataacta tgaaatcaag aacagatgat tttcgagtct
    24001 taaagtccca cgaaatttga cagagatacc agaaaataag aaacaatact gtcatatatc
    24061 caaaataata attttgaata aataagattg acagacttgt aaagtacaat aggagtttct
    24121 tttcagttat cagtagatgt aaaccagtta taattaaagg aatcaagata aaaacatcta
    24181 gccaggtttt tatctctaat tgactgacag tgaaactcat cagagcatag gaagtagata
    24241 aggctagttt taaagtctga gggatagatt gaaacaattt attcaaacta aaaaaggttg
    24301 acagaccaat caatccaaat tttaagagag tggtcagata gacagcatct ggcatgttcg
    24361 ttagatcaaa aaagtaaact agaggcgcga gaaaactacc caagtaataa ctagataggg
    24421 catagaagtt tagccctaga ccacttgtaa aggtgtaaaa cagactacta tttccatgta
    24481 ggatatttcg taaggctaca tcaaaaataa cgtattgatg aaagccatct cctaatagag
    24541 gagagttgtc gctattccag tagatacctt gagatagata tactccagac ataatcacta
    24601 caggaatgat gagagaaata aaataggttc gatatgtttt taaaaatgat ttcatgttac
    24661 ctcgtagaat gatagaaaac tcagttggtt aacccaactg agttttgaag ttttatttag
    24721 tctttccaaa gttctttaac ttttgcttgt acttctgcat tttctaggaa ttcatcgtag
    24781 gtttcatcga tacggtcaat gacgccattt ttagataaga caatgatatg gttagccaaa
    24841 gtttgaataa attcgtggtc atggctagca aagatgattg attctttaaa gtttttcaat
    24901 ccatcattca agcttgagat agattccaag tccaagtgat ttgttggatc atcaagtaca
    24961 aggacatttg attttaagag catgagtttt gaaagcatga cacgaacttt ttctccccct
    25021 gacaagacat ttacaggttt gttaacttca tctccagaga agagcatacg gccgaggaag
    25081 ccacgtagga aagtattgtc atcttcttct ttacttgcga attgacgcaa ccagtcaaga
    25141 attgattctc ctcctgcaaa atcagctgag ttatcttttg gtaggtaaga ttgactagtt
    25201 gtaactcccc acttgacagt tccttcatag tcaatatctc ccatgattgc acgaattaat
    25261 gcagtcgttt gaatatcatt ttgtccaata agtgctgtct tatcatctgg acgcaagatg
    25321 aaactaatat tatccaagat agtttcacca tcaatcttta cagttagatt ttctactgtc
    25381 aagagatcat taccaatctc acgttccgct ttaaagttga taaatggata tttacgacta
    25441 gatggtacaa tctcttctag ctcaatctta tcaagcattt tcttacgtga tgttgcctgc
    25501 cttgacttag aagcattggc agagaaacga gcaacgaatt cttgcaattg tttaattttt
    25561 tcttctgctt tagcattacg gtctgctagc aatttagcag caagctcaga agattccttc
    25621 cagaagtcgt agtttccgac atagagtttg atttttccaa agtcaaggtc ggccatgtga
    25681 gtacaaactt tgtttaagaa gtgacggtcg tgggatacta cgataactgt gttatcaaag
    25741 tcaatcaaga agtcttctaa ccaagtaatc gattggatat ccaaaccgtt agtaggctcg
    25801 tccaagagaa gaacatctgg tttaccaaaa agtgctttgg cgaggagaac ctttactttt
    25861 tcaccgttgg ccaattcgct catgttttgg tagtgtaatt cttctggaat gtttaggttt
    25921 tgaagtagtt gagaggcttc actctctgct tcccaacctc caagttcggc aaactctcct
    25981 tcgagttcgg cagcacgaac cccgtcctcg tctgagaaat cttccttcat gtagatagca
    26041 tctttctctt tcatgatgct ataaagtttt tcatttccca tgataacgac atcaatggca
    26101 cgttcatctt cgtagtcaaa gtgattttga cgaagaacag agagacgttc atctggacca
    26161 agagagatgt gaccagtagt aggttcgata tctccagcta aaatttttaa aaaggttgat
    26221 tttccggcac cattagcacc gattaatccg taagtatttc cttctgtaaa tttgatattg
    26281 acatcatcaa aaagtttgcg atcactaaaa cgtagtgaaa catcagatac tgtaagcaat
    26341 atttttctcc tatatgtgta atatatttat tctactagaa aatacagaaa tattcaaatt
    26401 tttatttgtc aattttgtgt aaattatatt tacagtatcc tttacacaaa tctgtaaaaa
    26461 gcaaggctga tttattttga taaattacgg ttatttcatt aaaaaaatgc tataattgaa
    26521 aggactatat cgaaggagaa caaaatgact aaacccatta ttttaacagg agaccgtcca
    26581 acaggaaaat tgcatattgg acattatgtt ggaagtctca aaaatcgagt attattacag
    26641 gaagaggata agtatgatat gtttgtgttc ttggctgacc aacaagcctt gacagatcat
    26701 gccaaagatc ctcaaaccat tgtagagtct atcggaaatg tggctttgga ttatcttgca
    26761 gttggattgg atccaaataa gtcaactatt tttattcaaa gccagattcc agagttggct
    26821 gagttgtcta tgtattatat gaatctagtt tcgttagcac gtttggagcg aaatccaaca
    26881 gtcaagacag agatttctca gaaaggattt ggagaaagca ttccgacagg attcttggtc
    26941 tatccaatcg ctcaagcagc tgatatcaca gctttcaagg ctaattatgt tcctgttggg
    27001 acagatcaga aaccaatgat tgagcaaact cgtgaaattg ttcgttcttt taacaatgca
    27061 tataactgtg atgtcttggt agagccggaa ggtatttatc cagaaaatga gagagcaggg
    27121 cgtttgcctg gtttagatgg aaatgctaaa atgtctaaat cactaaataa tggtatttat
    27181 ttagctgatg atgcggatac tttgcgtaaa aaagtaatga gtatgtatac agatccagat
    27241 catatccgcg ttgaggatcc aggtaagatt gagggaaata tggttttcca ttatctagat
    27301 gtttttggtc gtccagaaga tgctcaagaa attgctgata tgaaagaacg ttatcaacga
    27361 ggtggtcttg gtgatgtgaa gaccaagcgt tatctacttg aaatattaga acgtgaactg
    27421 ggtcctattc gtgagcgccg tattgaattt gctaaggata tgggagaagt ttataatatg
    27481 attcaaaaag gtagtgaaag agcgcgtgaa gttgcgggtc aaaccctatc tgaggtaaaa
    27541 ggggcaatgg gacttcatta ctttaactaa gtttatttta caagaaacta tcatttctat
    27601 ctcgaagaaa agatagtttt ttatttaccc ctgtaacatt tgacaaattt ttatagaatg
    27661 gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga ggaaacttcg
    27721 aatgtctaat tgggacacta aatttttgaa aaaaggtttt acctttgatg atgtattgct
    27781 tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta aattggcaga
    27841 taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta cagagagtca
    27901 aatggccatt gctattgctc gtgcaggtgg tctcggagtt atccataaaa acatgtcaat
    27961 tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag ttattattga
    28021 tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta tgggtcgtta
    28081 ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg ttggtatttt
    28141 gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa accatatgac
    28201 tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg agagtattct
    28261 tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc tttctggttt
    28321 gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta aagatgaatt
    28381 tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg aacgtgcaga
    28441 ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg gtcattctgc
    28501 aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga ctttgattgc
    28561 tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg tagacgttgt
    28621 taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg gtgttggtgt
    28681 tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg gtaaaacgat
    28741 tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg ctgcaggtgg
    28801 aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag gcgaaactga
    28861 aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg ctgctatgaa
    28921 gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca agctcgttcc
    28981 agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg ttttccaaat
    29041 gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta aagaactaca
    29101 cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc atcctcatga
    29161 tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga aaagaactcc
    29221 agtgaaaaca ggagttcttt tacaatgttg tcaatttcca tttacagaag ctttaccatc
    29281 ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta agcttgttgt
    29341 tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact gtctagtgtt
    29401 gtcaagttca ctcatcacat cgtcaagcag taatatagga gattctgtgg taatgctttc
    29461 cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt gaccttggct
    29521 tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat gaggaccgac
    29581 accagtattc tttttaaata aatctctgga tctacttttt tctaaagcaa ttttgaaaga
    29641 ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata ttgacaactc
    29701 ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta gtttttttat
    29761 gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat catctaacac
    29821 agaaaggaat gtttcatcta ttttttgagc tgattttagg taagtgtttc tttgctttag
    29881 gatgtggtta taattggtta agtcagataa atagattggc ttaatttgcc caagttccat
    29941 atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat cttcaggagc
    30001 aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt ttaagtgatt
    30061 aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg atccagtttt
    30121 tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga gatttttatc
    30181 tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta acatgtttgt
    30241 ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt ctattttcgt
    30301 ttctttgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga ttatctacca
    30361 gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt gtctttttta
    30421 actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac tttatcagct
    30481 tggtattcat cttgttcttc agaagtaggt tgtgtcaaca agatgtcaat gttcatgtca
    30541 gggatgtcaa ctttatcgcc aatacgaagt ttttttccac gacgactctc taattcccta
    30601 ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct atgtgtaatt
    30661 ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt gtattccata
    30721 attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga gagacagcga
    30781 gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa caagaaaatt tcaggttttc
    30841 gtgatataat agaagtctgt atataaggag gtaaatcatg gagttagtgc atggaatttc
    30901 aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc gttttaccgc
    30961 tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc tagagactgc
    31021 taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc tatacggtac
    31081 agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat tgacatttac
    31141 ctatgttcgt gatgagtttt taagtaggaa aaacgtgcta acctctcaga ttttggaact
    31201 tgtaaaagaa actctttttt cacccgcagt agttgataat gggtttgatc cggccttatt
    31261 tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg attcttttta
    31321 ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc aattggaata
    31381 tagtgattta cgaaatcgta ttttagctga aactccacaa agttcttatt cttgtttcca
    31441 agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta atgaggttga
    31501 aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg tgaaggttca
    31561 gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa atgtgggaca
    31621 atccattttg gaattaggtt atcattaccg ttctaaatat ggtgatgagc aacatttacc
    31681 catgattgta atgaatggtt tacttggtgg atttgctcac tctaagctct ttacaaatgt
    31741 ccgtgaaaat gctggattag cttataccat ttcaagtgag cttgatttat ttagtggatt
    31801 cttgaggatg tatgctggta tcaatcgaga aaatcgtaac caggctcgta aaatgatgaa
    31861 taatcaactg cttgatttaa aaaaaggtta ttttacagag tttgagttaa atcagaccaa
    31921 ggaaatgatt cgttggtcgt tgttactttc tcaagataat caatcttcat tgattgaacg
    31981 tgcttatcaa aatgccttat ttggaaaatc ttcagcagac tttaaaagtt ggattgcaga
    32041 gcttgaacaa attgacaaag atgctatttg tagagtagct aataatgtga aactacaagc
    32101 gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa atactatcca
    32161 gctgtaaaag aaaaggttta tcgaactcgt ttggccaacg gattgacagt tgctcttttg
    32221 cctaaaaagg aatttaaaga ggtttacggg agtgtcactg tacagtttgg ttcggtagat
    32281 acgtttgtca cagaagttga cggatatgta aaacaatatc ctggaggaat tgctcatttt
    32341 cttgaacata aattatttga gagagaagat tctagtgatt tgatgtcggc ttttacgagt
    32401 ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct tttttcagca
    32461 acggattatt ttttagaaaa tttagattta cttgatgaat tggtaacatc agcacacttt
    32521 actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga aatgtaccaa
    32581 gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc tggtacacct
    32641 ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct aactaatttg
    32701 caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt agttggtaat
    32761 tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga ttcagatttt
    32821 caggaagtag caagagaaaa gttgttttta cagcctgtaa agccaacaga tagtatgaga
    32881 atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga agtttctgaa
    32941 gcggattgct atcgacatca tattttatta aaattattgt ttgcaatgat gtttggttgg
    33001 acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcgtc cttatctctg
    33061 gaagttgaaa taacaagtcg ctttcatttt gtcatgttga caatagatac gaaagagcca
    33121 gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga tttagatatt
    33181 acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt cagtagcatg
    33241 aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga gacaattttt
    33301 gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc tggacatcat
    33361 ttaatagatg atggtgacat agttgatttt acaatattcc catcgtagta acctatcata
    33421 atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga gaggttttac
    33481 gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag acagaaatcc
    33541 agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca agtccttttt
    33601 acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac caaattgttt
    33661 tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt gatgaagatg
    33721 agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaacatca tttttacctt
    33781 tattttattt tatccttttt gctttatcga ttttaatttt tgtgacttat tatgtttgga
    33841 actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg gttcaatcaa
    33901 caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt atagaatcag
    33961 ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca agtaaggaaa
    34021 cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt tcagaaagcg
    34081 aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca acagttgcaa
    34141 ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg acagtagata
    34201 atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact gtaaccttta
    34261 ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt aacaataggt
    34321 cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc gatagagagt
    34381 catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt agatggatat
    34441 ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc tatggcggat
    34501 aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc tccggcttgg
    34561 attgttgcag tgattatctg tcgtgagtta gctgtgacag gtttaaggct tttattggtt
    34621 gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac ttttagtcag
    34681 atgtttgcta ttattttctt gctattacat tggactttgc ttggtcaagt tctactttat
    34741 gtagccttat ttttcactat ctactctggc tatgactatt tcaagggtag tgcctatgta
    34801 tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat ctttcttttc
    34861 gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac gtgaaacgtg
    34921 gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg gttcgattaa
    34981 ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa cgtttgactg
    35041 aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat ccagacaatc
    35101 aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat cagggacttt
    35161 ctcgtcaaga aatgaaaaag agagtggaag aagctctggc tttagttggc atgttggact
    35221 ttaaaaagag agagccagcg cgtctatcag gtggccaaaa gcaacgtgtg gccattgcag
    35281 gtgttgtagc cctaagacca gctattttaa tcttagatga agcaacgagt atgttggatc
    35341 ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac tatgatatga
    35401 cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc gtattggtca
    35461 tgaaaaaagg ggaaattgaa tcaactagta gtccaaggga gcttttctct cgaaatgatt
    35521 tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct ttgagccaga
    35581 atggctatga tttacctgaa aattatttga cagaaagtga gctagaggat aagctatggg
    35641 aattgctcta gaaaatgtga attttatata tcaagaaggt actcccttag cttcagcagc
    35701 tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa ttgggcacac
    35761 aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc caagtcaagg
    35821 gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag atattcgtca
    35881 aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt ttgaagaaac
    35941 ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag aagatgctgt
    36001 gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt ttgatcgtag
    36061 tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca tacttgccat
    36121 ggagccatct atattagtct tagatgagcc aacagctggt ctagatcctc tagggagaaa
    36181 agagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg tcttggtaac
    36241 gcatttgatg gatgatgttg ctgaatatgc taatcaagtc tatgtaatgg aaaagggacg
    36301 tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta tggaagaagt
    36361 tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata gaggcgtgtc
    36421 atttaaacga ttaccgatta agatagagga gttcaaggag tcgctaaatg gatagtatga
    36481 ttttggggcg ttatatccca ggggattcga ttgttcaccg attggatcca cgtagcaaat
    36541 tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc ttgacgaatc
    36601 tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct ctttcatttt
    36661 ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt tttcaactat
    36721 ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc acggattatg
    36781 ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc ttttcaactt
    36841 tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct ttattagcac
    36901 ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct atgagtttgc
    36961 gttttgtccc aaccttgatg gatgatacga ctcggattat gaatgcacag aaagctcgtg
    37021 gagtggattt tggagaagga agcatcgttc aaaaagtaaa ggcgatgatt cccattttga
    37081 ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct atggaagcgc
    37141 gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg actctaaagg
    37201 atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc ttaaaatctt
    37261 agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa aggtagggat
    37321 atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt tctgcttgtg
    37381 tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg agatggaatc
    37441 tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt caaatcagat
    37501 ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca gctttaccaa
    37561 ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca actgcgccaa
    37621 ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga tgttattatg
    37681 cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc aaaaggtgct
    37741 tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc aaaagtagag
    37801 gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa gatttctgtt
    37861 aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga caaggaaaat
    37921 gacgttctta aaattagcca attaaatagt aatagcgata ttagtgcggg agataaggtg
    37981 actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga agtggttgcc
    38041 acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag tgcagatact
    38101 cataatgtag atgtgataga attagtgggg aattcataat gagacagttg aagcgagttg
    38161 gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc cagcttctgg
    38221 gctcattttt cccccatgta catttggcta gtcattttct ttttctattt ctcttatttg
    38281 agacgataga agtatcagag tatctctacc tagtctattg ttttgttata ggcttggttt
    38341 atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc ttattgggag
    38401 ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga atgctagcta
    38461 tgattgtgct gacattcctg tttgaaatgg gtagttatct tttggctttt atggtagggt
    38521 tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg atgattttaa
    38581 attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta taagaacgac
    38641 atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac tagtattgtc
    38701 tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca cttttattaa
    38761 gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa acgactgatg
    38821 acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa caagaagccc
    38881 aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag cagtctaact
    38941 tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt gagattacag
    39001 aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct cgtagtgctc
    39061 aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa tcaattacag
    39121 aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac aaaatgttag
    39181 aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat aatgatgcta
    39241 tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca ttgactacga
    39301 aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg acagctgaag
    39361 gggaaaaagc aagtctatta gagcaaaaag cagcagctga ggcagaggct cgtgcagctg
    39421 cggtagcaga agcagcttat aaagaaaaac gagctagcca acaacaatca gtacttgctt
    39481 cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca gcagcacctg
    39541 tccgtgcaaa agttcgtcca acatacagta caaacgcttc aagttatcca attggagaat
    39601 gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt aatggagcac
    39661 agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct caagttggag
    39721 caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca gctgttgaat
    39781 caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca attggaaatc
    39841 accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat atttatgcag
    39901 attaatttac agagggactc gaatagagcc ctcttttcag gttttaccgt gacaatccct
    39961 attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaga atgaaaattg
    40021 tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct tgggtcgttt
    40081 tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat ggcagtaatt
    40141 tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg tcgctggaat
    40201 cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccacgttat cgacttgcaa
    40261 caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc agctaacgat
    40321 gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc tgaagaagca
    40381 gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct tacaaactgg
    40441 ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga agaagatgga
    40501 actttcgaag ttcttcctaa gaaagaagtt gcacttctta acaaacaacg tgcgcgtctt
    40561 gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat gtacgtagtt
    40621 gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat cccagttgta
    40681 gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc agctaacgat
    40741 gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat tatcgaagga
    40801 cgtcaaggtg aggatgcagt agcagttgaa gcagaatttg cagcttcaga aactcaagca
    40861 gattcaattg aagaaatcgt tgaagttgta gaaggtgaca acgcttaatt tatacaaata
    40921 gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa atataggaga
    40981 attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa atctggtgcc
    41041 ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga aaaagcgatt
    41101 gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aagctgaccg tgttgctgca
    41161 gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga agtaaacgct
    41221 gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac tacagctaaa
    41281 gtcattgctg aaggaaaacc tgctaataat gaagaagctc ttgctttgat aatgccttca
    41341 ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctatcggaga gaaaatctca
    41401 ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc ataccaacat
    41461 aacggtggac gtatcggtgt tatttcagtt gttgaaggtg gagacgaagc acttgctaaa
    41521 caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa agaattggat
    41581 gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca agacaacgaa
    41641 agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc aaaagctcaa
    41701 ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt ggctgcagaa
    41761 ggcaaaccag aaaaaatctg ggacaaaatt atcccaggta aaatggatcg cttcatgctt
    41821 gataatacta aagttgacca agcttacaca cttcttgcac aagtttacat catggatgac
    41881 agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga gtttgctcgc
    41941 tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga agttgcagct
    42001 acaatggcag cagccttgaa taactaataa tagaaaggaa gcaatttgct tccttttttg
    42061 tatagggctt atatttttcc tgaaattgtt tttcccccag tctcactcga ttagaataat
    42121 taaaacaaaa agccctataa taagggctaa gtgcatttag gagactatac ttcaaattca
    42181 tagtaagcgc gtcataacaa ggtatctatc ctaattcccc aacttccagt atactagata
    42241 aaaaataatt atcggaggaa aggtattgta ctatgatgat tcaactaagt gatttaggtc
    42301 aagttcacat tgtttgtggc aagacagata tgaggcaggg aatagactca ttagcctatg
    42361 tagttaaaac ccactttgaa ttggattctt tctccggtca agtctttctc ttttgtggtg
    42421 gacgtaaaga ccgctttaaa gtcctttact gggatggtca aggattttgg ctactatata
    42481 aacgctttga gaacggaaaa ctgacttggc taagtacaga aaaggatgtc aaagctctcg
    42541 cacctgaaca agtagactag cttatgaagg gcttttctat cactccaaaa atatagtaga
    42601 ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcga tttgactgtc
    42661 ctgatcgatt tgtcctgttc ttatttcatt ttactataaa tccatcagaa agtcgtgatt
    42721 tctattgaaa tgaggacttt ctttttacac tcatctgctt tcaaaaagca ttctagtccg
    42781 tctccgatta acgatggact ttatcacctc cttctctagt ccttgtatga catcttccaa
    42841 agttcgaaag gctttattct
//
LOCUS       DAVBOM010000012        40568 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBOM010000012 DAVBOM010000000
VERSION     DAVBOM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40568
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.012"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..258)
                     /locus_tag="VQ878_000697"
     CDS             complement(<1..258)
                     /locus_tag="VQ878_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095076.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERG"
     gene            complement(701..1156)
                     /locus_tag="VQ878_000698"
     CDS             complement(701..1156)
                     /locus_tag="VQ878_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095077.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(1431..3168)
                     /locus_tag="VQ878_000699"
                     /pseudo
     CDS             complement(1431..3168)
                     /locus_tag="VQ878_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(3331..4215)
                     /locus_tag="VQ878_000700"
     CDS             complement(3331..4215)
                     /locus_tag="VQ878_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET3095078.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLINKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(4327..5181)
                     /locus_tag="VQ878_000701"
     CDS             complement(4327..5181)
                     /locus_tag="VQ878_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET3095079.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(5239..5997)
                     /locus_tag="VQ878_000702"
     CDS             complement(5239..5997)
                     /locus_tag="VQ878_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3095080.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(6059..6247)
                     /locus_tag="VQ878_000703"
     CDS             complement(6059..6247)
                     /locus_tag="VQ878_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET3095081.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(6570..7136)
                     /locus_tag="VQ878_000704"
     CDS             complement(6570..7136)
                     /locus_tag="VQ878_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095082.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(7404..9083)
                     /locus_tag="VQ878_000705"
                     /pseudo
     CDS             complement(7404..9083)
                     /locus_tag="VQ878_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(9175..9336)
                     /locus_tag="VQ878_000706"
     CDS             complement(9175..9336)
                     /locus_tag="VQ878_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095083.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(10020..10334)
                     /locus_tag="VQ878_000707"
     CDS             complement(10020..10334)
                     /locus_tag="VQ878_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095084.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(10300..10689)
                     /locus_tag="VQ878_000708"
     CDS             complement(10300..10689)
                     /locus_tag="VQ878_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3095085.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(11077..11871)
                     /locus_tag="VQ878_000709"
     CDS             complement(11077..11871)
                     /locus_tag="VQ878_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095086.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(11871..12878)
                     /locus_tag="VQ878_000710"
     CDS             complement(11871..12878)
                     /locus_tag="VQ878_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3095087.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(12878..13885)
                     /locus_tag="VQ878_000711"
     CDS             complement(12878..13885)
                     /locus_tag="VQ878_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3095088.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(13875..14900)
                     /locus_tag="VQ878_000712"
     CDS             complement(13875..14900)
                     /locus_tag="VQ878_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3095089.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(15293..15511)
                     /locus_tag="VQ878_000713"
     CDS             complement(15293..15511)
                     /locus_tag="VQ878_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095090.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(15757..16035)
                     /locus_tag="VQ878_000714"
     CDS             complement(15757..16035)
                     /locus_tag="VQ878_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095091.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(16249..17880)
                     /gene="rlmD"
                     /locus_tag="VQ878_000715"
     CDS             complement(16249..17880)
                     /gene="rlmD"
                     /locus_tag="VQ878_000715"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3095092.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRGLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(17954..18928)
                     /locus_tag="VQ878_000716"
     CDS             complement(17954..18928)
                     /locus_tag="VQ878_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET3095093.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(19002..19616)
                     /gene="pmp23"
                     /locus_tag="VQ878_000717"
     CDS             complement(19002..19616)
                     /gene="pmp23"
                     /locus_tag="VQ878_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET3095094.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(19616..20590)
                     /locus_tag="VQ878_000718"
     CDS             complement(19616..20590)
                     /locus_tag="VQ878_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET3095095.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(20598..21854)
                     /locus_tag="VQ878_000719"
     CDS             complement(20598..21854)
                     /locus_tag="VQ878_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET3095096.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(21916..22347)
                     /locus_tag="VQ878_000720"
     CDS             complement(21916..22347)
                     /locus_tag="VQ878_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095097.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(22349..22948)
                     /locus_tag="VQ878_000721"
     CDS             complement(22349..22948)
                     /locus_tag="VQ878_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET3095098.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(22935..23774)
                     /gene="prmC"
                     /locus_tag="VQ878_000722"
     CDS             complement(22935..23774)
                     /gene="prmC"
                     /locus_tag="VQ878_000722"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET3095099.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(23774..24853)
                     /gene="prfA"
                     /locus_tag="VQ878_000723"
     CDS             complement(23774..24853)
                     /gene="prfA"
                     /locus_tag="VQ878_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET3095100.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(24863..25342)
                     /locus_tag="VQ878_000724"
     CDS             complement(24863..25342)
                     /locus_tag="VQ878_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095101.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDRNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEIAENEVVAIYDLTIEK"
     gene            complement(25332..25931)
                     /locus_tag="VQ878_000725"
     CDS             complement(25332..25931)
                     /locus_tag="VQ878_000725"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET3095102.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            26054..26236
                     /locus_tag="VQ878_000726"
     CDS             26054..26236
                     /locus_tag="VQ878_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET3095103.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            26373..27746
                     /gene="mnmE"
                     /locus_tag="VQ878_000727"
     CDS             26373..27746
                     /gene="mnmE"
                     /locus_tag="VQ878_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET3095104.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(27793..28728)
                     /gene="dapA"
                     /locus_tag="VQ878_000728"
     CDS             complement(27793..28728)
                     /gene="dapA"
                     /locus_tag="VQ878_000728"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET3095105.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(28784..29860)
                     /locus_tag="VQ878_000729"
     CDS             complement(28784..29860)
                     /locus_tag="VQ878_000729"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET3095106.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(30202..30274)
                     /locus_tag="VQ878_000730"
     tRNA            complement(30202..30274)
                     /locus_tag="VQ878_000730"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30239..30241),aa:Thr,seq:ggt)
     gene            complement(30374..30883)
                     /locus_tag="VQ878_000731"
     CDS             complement(30374..30883)
                     /locus_tag="VQ878_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET3095107.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(30881..30977)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            31006..31437
                     /locus_tag="VQ878_000732"
     CDS             31006..31437
                     /locus_tag="VQ878_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET3095108.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            31519..31896
                     /gene="mscL"
                     /locus_tag="VQ878_000733"
     CDS             31519..31896
                     /gene="mscL"
                     /locus_tag="VQ878_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET3095109.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(31938..32911)
                     /locus_tag="VQ878_000734"
                     /pseudo
     CDS             complement(31938..32911)
                     /locus_tag="VQ878_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
     gene            33066..34289
                     /gene="pepT"
                     /locus_tag="VQ878_000735"
     CDS             33066..34289
                     /gene="pepT"
                     /locus_tag="VQ878_000735"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET3095110.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(34325..34882)
                     /locus_tag="VQ878_000736"
     CDS             complement(34325..34882)
                     /locus_tag="VQ878_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095111.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENLESNNGSDADFDKVDALLDQLSAKSKDKTALLESTKAILV
                     LNHQIQSKASASEETSPARNAEANSDNTSAENQPNATAESNIEIASDENKPSNTRDSK
                     PAESTSENETTESSTTTGNQEKPVE"
     gene            34847..35068
                     /locus_tag="VQ878_000737"
     CDS             34847..35068
                     /locus_tag="VQ878_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095112.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(35339..36350)
                     /locus_tag="VQ878_000738"
                     /pseudo
     CDS             complement(35339..36350)
                     /locus_tag="VQ878_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(36576..39695)
                     /gene="phtE"
                     /locus_tag="VQ878_000739"
     CDS             complement(36576..39695)
                     /gene="phtE"
                     /locus_tag="VQ878_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET3095113.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(39906..>40568)
                     /gene="phtD"
                     /locus_tag="VQ878_000740"
     CDS             complement(39906..>40568)
                     /gene="phtD"
                     /locus_tag="VQ878_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET3095114.1"
                     /translation="QYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLL
                     ATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPQTEKPEEDKEHDEVS
                     EPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKI
                     AEAEALLEKVTDSSIRQNAMETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPAP
                     IQ"
BASE COUNT        11885 a         8198 c         6696 g        13789 t
ORIGIN      
        1 acctctttct ttcacaattt caattttcaa agtcaattca taatcttcaa caggattgag
       61 cattttatct tctcctacaa tatcgacata agatacatta aacttctgac aaatgatgtc
      121 aattaattcc gtagagactg aactagttcc attttcataa cgactcaagc tatttcgaga
      181 aattcctata attcgtgcaa attcaggttg tgttaagtca tgtgttttac gtaaggattt
      241 tatgttcttt ccaatcatag taaactcctt tatttttata attcaattat agcataaaaa
      301 agtataacgc accaattttg gtgcgttata ctttttttct agcctaaact ttacttctat
      361 aaaagtcacc taaagagcca taaatattta ttcttgtatt aattttttcg atgcgcaaac
      421 gatatctaca aatacatcta taacgattca ccttttagga tttttattgt caaaattgcc
      481 tttatctaca aagacaaaat gcttataaaa tagcttgaaa tcaaggatta tcaccttttt
      541 cgttgtagca acactccaca tgtgattatt aggctattag caaagcgtat ccaatacctc
      601 aataaagtgt tgtttttact gatattttaa ctatattgta tagtctacta tttaaatctc
      661 aattaggata ttttatagaa tacccaaaat tcaacaataa ctaaaagtaa gattccattg
      721 tatttccttg ttggtctttc atatcacgaa ttttattttt cagaatatta aagttacaaa
      781 tttcatctct aatatcgtta tccgctctgt agccattaat catctcagtc agagttttcc
      841 ctttactacc attctttata gtagtattta ctctttttat actgctttca aaaggctcat
      901 atgttttata cttaattact tcgtctttaa aattaaataa aggtgtatcc ggcttagcat
      961 tccataaaat aatcaaccac attatagcat tataaagctg ctttgcagtt tcattccact
     1021 tttcaggttg taaatttcca ctccctgtat tgtcatattc ttgtctatta tttacatgag
     1081 aatcacctac aagtggatta aaaagaggta gccctttgtg attaattagt tctaaaaaat
     1141 cccttgccgc acccatgcaa cactgaataa cttccttctt gccatcaatt ttactctcag
     1201 cgataaatac ataatattca tcttcaatag ttgctcctgc atcactatgt ttttgttgat
     1261 ttgctaacag cttaatatgt gctttaggct aaacttcaaa atctctaaca attctttgtc
     1321 ttgtttcatg tcctctacaa ttcatttaag ttctccttta caagtttagt aactagcctt
     1381 attatactat ataagatatg aaatgtacca taatcttcat caactagttt ttagaaaatc
     1441 acaaatccat ctggagagat gacaagctga ttctccaatt cttggcaatt gcttgctagt
     1501 gctactgctt ctttctctaa aagataatct tctgttgatt ggttgaatat tgctttgagg
     1561 atccgtcctt cgtatttcca ttccagagct actaaatcag atttgatttc ttgaaggcta
     1621 tacttgccat gcgaaataat tactgacgcg tatttccgaa tcttaatcag cctcttcata
     1681 aagttcagca tatcattgtc acttgataca cgttcccaag gcatacaacg acgacaatct
     1741 ggatctggtc ctccagtcaa ggctagctcg gttccgtaat aaatgcacgg tgttcctttt
     1801 tgtaaaaaga gaaaggctaa ggctgattta accagttgaa catcttcatt ggccgtccac
     1861 aggattcgct ctgtatcatg tgaatccaag agattaaaca tgacctctga aatctgctgc
     1921 ttgtaataca tagactctcc attgatttca tcgatgaact ggtctgtctt cttaattcct
     1981 cgtaagaaat agtccttgat actatcagat aaaggataat tcatgatggc atggaactca
     2041 tctccattta gccaaggctg agatgtatgc cagacttctc ctaggatata aagatcagga
     2101 tttttagcta aaactgcctt acgaaaatcc ttccagaact gatggtcaat ctcattagcc
     2161 acatccaaac gccaagcatc gatattaaac tcttcaatcc aataagtcgc aacctttaaa
     2221 agataattct tgacctctgg attggctgta tttagcttag gcatatagtc ctcgaaacca
     2281 aaaacatgat agggtaagtc tctcttatta actagttttt cagttgtcac tgggaattgt
     2341 tgaatatgga accaatcctt ataagcagac tgttcaccat ttttgacgac atttttccat
     2401 tgaagagatt gcgaaccaat atgattaaat accgcatcca gcatgacttt catgccacga
     2461 tgatgcgctt gatccaccag ttcccgaaag gtctccttgt ctccaaaatg acggtcaatt
     2521 tcaaagtaat ctgtcgtatt gtacttgtga ttgcttgtag attcaaagat gggacaaaga
     2581 tatagtccag taatacccaa gtcttgcaag taatccatat gatcaataat cccctgtaaa
     2641 tcaccaccaa agaaatcatc gctcttaggt gtgacagatg aatcccagtc taaagtccct
     2701 tctgggttta atagagcatt gccattggca aatctttcag gaaatatctg ataccatacc
     2761 gtatttgaaa cccagtcagg aaccttgcag gcatcaatct tgaagataag gcaacttaaa
     2821 tccattccca attgcatgaa gattttctag agaattttcc acacaccctt tatcgccata
     2881 caaaatattt tgaccttctg tatctctgag ctcaaagaga tactggatac gtgcaaagtc
     2941 aactgacact tcaacctgcc aatggtcaaa taaggtacca gaagttatct tgaccatttc
     3001 ttttgtatcc tgataaaact cctccataaa gataaaaggg tccccatagt gcaagttgat
     3061 gctttcaatg tcccctttct tagttcgaat tcgaatatgg agtttcttat ccttataaag
     3121 ataggcatac tccgactcag gcctatggta aatagcactc aattccatca atttgtctcc
     3181 taaagtattc attcaaattt tacgcaaacg ttttcaaact caatgaatcc agtatactat
     3241 ttttgtaaac tatttgcaag gaatgtccgt tgttaaagga actatctttt aaagtataca
     3301 aaaagcctta aaaaaggctt tctctatata ctaatcctct ttcggttttg aaaatacttc
     3361 tactcgctga gctaggactt tgatttctac aggtaggtta tctgatttat ctccgtcaac
     3421 atctgactcc aattcactat ctgaagagat tttaatatta cgcgctttga tatactcgat
     3481 attatcattt gcgacaacat ccccttttaa taaatcagga atgacggata atttggagaa
     3541 tatagaggca tctttcagaa tcaaaatgtt ggcatagccg tccttgtttt cttcaaagat
     3601 tttcttatca gcgaagtaat ttgtcaaaag gaccaaaaca tggctagctt caccaacata
     3661 atttccattt tctgtctcaa ccttaatgtt aaagacctga tctgtcatga cagacttcat
     3721 ggtatttaca gcataggtta aaataccgaa ttttgttttg tcctctattt caacattgtg
     3781 aatcgcctca ggcagagaac cgatactaaa gatataacca aaatagttgt catttgcttt
     3841 accgatatca atcttattga ttaaatcaaa atccagttcg tcaattgcgc catcgatgtc
     3901 ttgattgatt tccaaaagtt ttgtaatgag gttacccgta ccgcctggga taatccctaa
     3961 cttaggaatg tagtctctct catcaatacc tgaaatgact tcattgacag ttccatctcc
     4021 accaaacaca accactgcat catactgctc acgagaagct tcttcagcaa aatgtgttgc
     4081 atccagcgct ttttcggtaa ttttggtttc aacatattca aagtattctt ttgctttatt
     4141 ctccagcttt tctttgtaat ccaaagcctt ctcgccacca gaagtagggt tgataattac
     4201 cattgctttt ttcattgatt ttatccttaa ttttaaacag aaatgtttac atttcgtcgt
     4261 atgcaagtaa atgtaatcct attatacaat gaaaatacag aaaagagaaa tctgacatac
     4321 tggagattaa tacgctttta ttctattttc ccatcgccta actacatcct ttaagggttc
     4381 atccaagtaa gaataggcct tatccttgat ccaatcagga ataccgtaag ctgcctctgc
     4441 tatgctacaa gtgattgctg cgagagtatc actgtcgcca ccaagtgaga tggcatttct
     4501 tatcgcatct tcgaagtctc tactttcaag aaaggcgata atggcttgag ggacagtttc
     4561 ctgacatgtt tcgttaaaac gatagttagg acggatttca tctaaagttt gagatagatt
     4621 gtaatcgtat tctttttcta tataatcctt aattcgtctt ttacactctg taggattgtc
     4681 gttaattgat tgctcgtact ctctacaata accaccaaag taaaaacgac atagaaagat
     4741 agcatcagct gtagccatag cgcctttgac accttctgga tgattatgag ttacctctgc
     4801 agaaagactc gtaagtcctc tagatgatgg ccacatacca gttttcgcat aaaaaccaca
     4861 gtccatgatc caagcacatg gagaaatacg catagctgat ccattcccaa agctattata
     4921 aggctcacgg ttatcgctgt ttagccatgc attaaaccga gcaccgtaat cagcattcgg
     4981 atacattctg ccatatttct tcatcgcgtc aatgaaatcg tctttttgtc caccattcat
     5041 aattgcttct gcaacagcac aggtcataac cgtgtcatct gtaaaaaagc agtccttccg
     5101 aaataaagga aagtcctttg ttttgatatt gttccattcg taaacagaac cgacaatatc
     5161 tccaataatt gctccaagca tcagattcct ccttgttcat tttgatgctt tttatattgg
     5221 ttatctacca tatttatttt agaaaataac atcctgttgg attttaaaaa tttcattttt
     5281 ttcaaaatag ggttttacca tttctttcca cctagctcta tgaaaattga ttgattttaa
     5341 aggagatagg ccataatttc ccaatgcata accatcattt acttcaacaa caagtgttct
     5401 gccatcgcga gtaacaccga tatctagtcc ataagctatt ggcgcatctt tccaacatga
     5461 tatcgcttca tcaattacac ttgcatcaaa ttgtgcatga taatcacctg tatagggtcg
     5521 aacatctaat acgcgaccat ctaacacaaa acaacgccat tcagctatga attctacaac
     5581 ctcactaatc catataggat agtcgaaagg tagaccaata cctattaaat catgggttcc
     5641 attaacaact cttccagtaa agacttttga accagcttta ggcttaataa attttcccca
     5701 attatcaggt atattcacaa tctctcctaa aataccagca taaatctttc gaccataaaa
     5761 ctctttaagc tcaataggat agtcatgaac cggaacgttt aagcccatca tttttagtaa
     5821 tgctctagtc tccattatat aatctacaac tatatcttca cttgttaact cttttatttc
     5881 agaaaaagat tgatataaaa taacttcttc tccttgtaag taggcaccta cttgagcatt
     5941 gtatttatta attgaaacct cacttggtaa tttactttgt ctaatataaa caaccatttc
     6001 atcactccta tatcactagt gttacaccaa tttgtaaaaa ataatagcaa ttttgctctt
     6061 atttttttga gtaaatagcc cccataatat catcgaaata atcaacggta tttaggagta
     6121 attcaataac ctgggacttt gttagtcgca ttccccttct atctctagca tcttctacta
     6181 aattttcaag tttctctaga tttttatcat ccaagctaat cattattcta tttttatcgg
     6241 ttgccatttt catcacctcg agttaattct atcacaggtg taacacttgt gtcaactggc
     6301 ttttataata cattagttta aaagtggaga ggatttttaa cacagtaact ttaaatcttt
     6361 ggtattaaaa aattttcaca atatttatag aaataaaatc tgtctcaaat cagttatcaa
     6421 atctagtata aattatgagc ggctactcta atactttccc tctaaacaag aaaaagactt
     6481 acactcaagg gttttcttcc ccccccttcg ttataacgtt ttgactcttt tactagcaaa
     6541 ggtatatact cacaaggaac tttggttgac tattgaatct ctccaacttc ttctttaaca
     6601 tatccttcta catcttcaat ctctacaaac attgggtcta agtgacacaa gaaatgccaa
     6661 acttcgatcc ctttttttct gtaaagaatc gcttcaccgt cttcacttcc gaaaaagctt
     6721 ctgtcgattt catatccgcg gctttctaag aagtcttttg ctttacgata gttcgtttct
     6781 cttgtttcga cataggcttt aacttcatgg ttgttaacga catatgcatc aatttttgaa
     6841 tatccttcga tcactctatc atttttgagg gataaatttg aaatctcttt ccaaataatg
     6901 tttacatttt cctcaggatc gaacataaat ttagataaag gaacaatatt tccgttaaaa
     6961 ataatttcca tataatccgg tatgttttta ggattaaaat actccacttc aaaaccatct
     7021 tctgtttcca gagtgtatcc cgggatttga gctacaaagg ctttcccatc ttctatggaa
     7081 tcaaatgcta ctaaatcttt agaataatca ttttggtaca attccaatat aaccatcgat
     7141 aatctctcca ttttcattat caggctaatg taaataagca cgtcacctga ccaattcagg
     7201 ctctctgtat catctcatca tatttcctac ttactttacg agtcctatac ccagaacaca
     7261 ccttatcgac cttcggtctc acctcgtcgc attggctgaa catctacttt tacttcgctg
     7321 atgcttcaac tcgtacaagc agtgataccg cctcagcgtg atgcgtcagt gggactcaaa
     7381 aagtttgggg aaccttttga ggattaacta cgtttctcta ataaacttac acattcaact
     7441 tgttcatcat tgtccaaatc tatgttgaga ttttcttcta taattggtag cttaaaagta
     7501 atggatttta gccattgtcc gttagattgt ttttcttcat aaacttgaat ttcagaaatc
     7561 aaagctgaaa ttaactgcct acgctctaca tcattcatga ctttatagag cttatcaaaa
     7621 tagatcagaa ccttatatat gttatctcct gtaagctttt cagcttcaat agtctgtttc
     7681 tttgctttcg catcaattag tgatgattct aattcatcta ttttgtcata catacgatat
     7741 agtctatcat ctaaatcctg tttccttctc ttataatgct tatcttcaac atctaaatta
     7801 tctatttcct caattagctt aaactttgta gaatgactct ttctcaattc cttttggtaa
     7861 ttatctattt ctttttctat ttcagaggta tccaccttca tgttgatttt ttcttgcatc
     7921 atagaagcaa atttcggatt acttactatc ttgacaatca cctctgcaac agcatcatct
     7981 aacaattctt ctctaatttg cttactgaat gtacacttat gacctcttat catctgccta
     8041 tggttacaac catagtaata aaaatcttta tactttgtgc catctttctt tttcttgata
     8101 cacttgttcc caaacattcc cactccacat atcgggcatt ttacaattcc agaaagcaag
     8161 tgtgtgcgtg tatcttttcc tttattcaca tgctcatatt tctttgcttg agattttagc
     8221 ttaacctgag cagcttacca aacttcatcg gaaactatag cttcatgtat cccttcagat
     8281 attagatatt catcttgttc aacctgctta tattcatttc ttgtaccatg aactttttct
     8341 aaagttcttc ttccaaatgc tattttccca ttatatacag gattctttaa tatctttctt
     8401 ataagacctg catcaaacaa aggattctta ccattctgtc ttgggatttt tctaattcca
     8461 tgattctcta agtatttaga tatcccattg gctcctatcg tagtatttac atactggtcg
     8521 aaaatcgttc ttattgcaac tgcctcttcc tcatttataa acagcttgcc gtcttcaagt
     8581 ttatatccat acggagcaaa gccaccattc cattttcctt cccttgcttt ttgaatgcaa
     8641 ccttccattg tttgaatacg gatgttttct ctttctattt cagccacagc tgataaaaca
     8701 gaaatcatta gtttcccagc atctttagat gaatcaatgc catcttcaac gcagataaga
     8761 ttaactccat aatcctgcat tatctgaagt gtagaaagaa catcagcggc atttcttgca
     8821 aatcttgata acttaaacac aagaacaaaa gatactccat cttttccaga ttttatatct
     8881 tccatcattc gattgaactg tattctacct tcaatagact tgccagactt cccggcatct
     8941 tcatactctc caacaatttc ataatcgttg taaatagcaa aagctttcat tcgtgatttt
     9001 tgtgcctcta acgaataccc ctctatctgt attgacgtag atactcgtgt atagaggtat
     9061 acttttattt tttcttttga catagtatta acctcaatat aatttttcta tatcatatat
     9121 aattttttta atttaagttt ggactatcat ttcaagtata ttataacact tttattagtc
     9181 cgtctcaatt tgtgtttttg ccatgtcaaa actatttttc atctcttgat tttttgctgg
     9241 cgttggatcg ggtagattat ctaaatctaa agcaccagca tattttgcaa tcagatttgc
     9301 tattaaatca gccaatccat tccagtcatt gtccaatata tacctcctct aaagttttat
     9361 atctaataat tatttgttta attaagtttt ttgacattga caagtgcttt ggattagcaa
     9421 cataggaatc tcacctccgc ctctattccg gatgagccgg cttcaacctt agaagtatca
     9481 ttatcctcat tttcttcata gcggataggg tatccctccc tatattcaaa ctcttactta
     9541 tcgctcactt tctttttact tagcagaact ttttttgccg aattattcag ccgaaagatc
     9601 ttgacggata ggttattacg ctccaaaaat aattaacgtc ttgtcttggt ctattcaatt
     9661 gttaaggttc aaaatttatc gagagttatt aatcttttta aaatttgacc atcagaaaat
     9721 atttatctta atgtaacaaa attctataaa ttaccctctt atacttaaca gtgaaaagaa
     9781 gtctttcttg gtaaccaatt ttgaaataga atttgcttat ataaaaaggt caaattccca
     9841 ctgcataagt agcagtgaaa attagaccct cttggtaact gtcatctaaa agtcttctag
     9901 catttcttta attttctaat cgcctttaaa gtgtcatatt tatatttttt tatctctggc
     9961 atactttgat acctttttag acttaaagtc tttaatagtg cctttccacc tctttttatc
    10021 tataaagatt ctcctacatc ataattcatt tttttattta aacctttctg tcttagtttg
    10081 tctttatctt cttcatacca ttttaagatt gtcacatagt ggttttgata ggtcttacca
    10141 ctgctttcca tgtatctgga tagtttattt atcattatat ctgtgtgtga gtttaatttt
    10201 tcttttagat ttttatattc ttctttgctt aaccttacat ttttgaattc tccataaaaa
    10261 atgggggtgg actttttatc tatctctccc tctctctctt tatctatctc tatatctttc
    10321 catgtaattc caatctggag tacctctact gtctatcggt aatttaattt tgatatctgg
    10381 caatactgtg ctagatattt gatctttata ttcagtattt tttaaagctt gcctaataat
    10441 tgaagttaaa tagaatgcta cttctttatt caattcttta ttttttaatt ttaaacaatg
    10501 aattttcata tctaggcttg ctttatattt atgataaaag actgctccta aaaatgaaac
    10561 agatataaaa ttttcaaaaa ctctataatt tttatcatct atatcttcgt agtaacctaa
    10621 gataccattg tcaatatttg tagcactaat tctaggagtt tttccatcga gtaaatatct
    10681 ttttggaata gatgagcctg ttggtacttg actcgatttc cccttttttt cggtaataaa
    10741 tatttctttt tattttgttg tccgatattt ttcctacctg tcctttgtag gatgagtatt
    10801 ttctagattt tcttgaataa ctttttactt gaagttttag cttttgaact agtcgttgta
    10861 ctttcttttt gtttattatc agtcctgatc tttttaatat tgctgttatt ctctatatcc
    10921 tatttttcat tcatgatatt cttttactaa ttttatctta aattctgtgc tgtatttgcc
    10981 attaaaaaac tgacctcctt tagttagttt tttggcctaa cttttgaggg tcagttcaaa
    11041 atttgcgact tttaaatgaa ttccgatatt caattattaa gagctaacat ggtgcttgcc
    11101 aataggaatc attagaggcg aattggaaat agggtcacgt ataatttttg cttcaagatt
    11161 aaagatatct ttaactagtt tatcatttag tatatcttca ggctttccct ctgcaacaag
    11221 tttaccttct ttaattgcaa ataggtaatc agcgtatctt gctgttagat ttatatcgtg
    11281 caaaatcatg caaatggttg tcttatattt ttggtttaga tcagtcaaga ggtctaatag
    11341 ttctatttga tatgagatat ccaagtaagt agttggctca tctaaaagta ggatacttgt
    11401 atcttgggct agggctagag ctatccatac tctttgcctt tgacccccag aaagttcttc
    11461 aactaggtta tttgctagat cttcaacatt ggccttaacc attgatctgt ttattatttc
    11521 aaggtcatct tttccaagac tcttaaaagg ctttctgtag gggaaacgac cacggcttac
    11581 aagatcagct actgttattg attcagggat tattggagat tgaggtaata tagctatgtg
    11641 ttttgctaaa tctttttctt tataagaatt aattgattta ttatcgagca atacttctcc
    11701 ctctaatggc tttataagtc gagacaaggt tttaatgagt gttgatttcc cacaaccatt
    11761 tgacccaata ataactgata ttttttcttc aggtattttt atatttatat tttccaagat
    11821 tattttttca tcataaccgc aggtaagatt atttgaccac agacctttca ttatatattc
    11881 ctcctgttca tttttattag taagtatatt aagtatggtg aacctaacaa gccagttaca
    11941 acacctactg gatatctagc tggtaaaata ttttgagaga atatgtctga taacaaaact
    12001 agtaaaattc caaccaatcc agctaatatt gggcttcttt tcttgccaat atttaaggct
    12061 atgggaccag ctaaaaaaga tatacaagct attggtcctg taattgaagt agaaaaagca
    12121 gttaaagata cagcgcaaaa aattaaaaca agccttgaaa gctcgggatt tgctccaagt
    12181 ccgattgcta tttcttcacc aagttcaata atttctagtc ttttattaaa aaataaaact
    12241 aatatagtag caataatact tactattaga acaagaggta tgtcatctaa ctttgtaaaa
    12301 gataaagagc cactgagcca tctcataact tcttgtaatt catatcttgc tactttcaac
    12361 aataaaaatg aggtgcctgc tcttgtgaca gcttgaaaac caatgcctaa tattatcagt
    12421 cttgctgctg aaaaaccatc ttttttagct agtaaaaata atattaaaga tgatgttagt
    12481 ccacaagtta ttgaaataat tccagtagtt aaactatttg tttttaatac caatatgcaa
    12541 aagaccgctg caatagatga agaacttgtg acaccgatta tatcaggact tgcaagagga
    12601 tttcttaaca tagtttgaaa gataaatcct gccaatccaa aagaccagcc agctataatt
    12661 cctgctaata attttggtaa tctaatttcc ataatcgaaa aactagctcc aggaacagtt
    12721 tcactattta agactttaat caaagttgaa aaagaataac tttcatctcc gataagtaaa
    12781 atgaaaaatg atagactgat tattattaat aaaaatagtg aggaaaatag tgttattcta
    12841 ttttttcttt tttgaatacc tataattaaa ttttgcatta gttattaacc cctctatttt
    12901 tcatagttac ataaataagt actggacccc cgattattgc agtaattatc cctacttcaa
    12961 tttcacctgg tttacctaac atacggccga ttatatcaca tataagcaag agctctgcac
    13021 ctataaaaga tgaagaaatg gtcattgtgc gtatatcttt gcttataaat aagccacaaa
    13081 agtgaggaac tataagacct acgaagccaa taggtccacc aattgcagta atacttgaac
    13141 ataaaagcac acttgcaatt attgcaagtg atcttatcct attaacatta actccaagac
    13201 caacagccat ttcatcaccc atagctaaag cgtttaaatc tgatgaaata aatatagcta
    13261 tcaaatgacc taaaattata aaaggtagta gtgtagatat agaagataat gtagctgctc
    13321 caaggctacc tatttgccaa aatctaaatt tgtctaagac gttattattc ggtaaaatta
    13381 aaaaacttac aaaactgctt aaagccatac taacacaagt tcctgataag gcaagtttta
    13441 taggggtaag gcctgctttt ccgcttacag caatcgcgta tacaaaaatt gcacttacta
    13501 agccaccaat gattgcaaaa cttatatggc ttatgcttga tgaaattcct aaaaaagaaa
    13561 gaccaattac tacactaaga cttgctcctg tgtttatacc gagtatacct ggatcagcta
    13621 ttgggtttct agtaactgat tgcatcaata caccgcttat ggcaagacta gaacctgcta
    13681 aaattgcaaa aatagttcta ggtattcttt tatatataat tgatttaata aaatcatcat
    13741 ttgtattacc cattccaaaa gctgctaaaa aatctctgat attaatttct tttgttccaa
    13801 gctttaatga caaaaatatt gtaataagaa gacctaggca gattacaaaa attatgccta
    13861 ggtttatttg ttttttattt cgcatttttg catgcatttc ctaaaagatt taggtattct
    13921 tcaatagtat agtttattga aagtggtgtt ggagtgcatg aggctgctaa cggtgtatta
    13981 tctggaatta cagcaacggc accattttta attgcattta ttttacctaa aagaggatct
    14041 ttttgtaaag cttcaagagt tttatcatca ccataagtta tgattacatc agcatcattt
    14101 atcttatttg cttcttctgc agaaatttcc tttgcaaaac tatcttcact ctcaaattct
    14161 tttaatgatt cagggaaaac tagacctaaa tctgttaaat aatttgctct tggatctttg
    14221 ctagtataaa tccagaattt tgatgtatct gcagcattaa tcatagtaaa taatactttt
    14281 tttcctttga tttttccttt gatttctgga tgtttttcta attctttgga tatacgagct
    14341 tcagtatttt tgattaactc atcaccttct ttttccatac ctaaggcttt tgaatcaatt
    14401 ttaatcatat ctctccataa agtttgccaa ggtttagatt tgtatgctgc tacaggagca
    14461 atttttgata gagtgtcata atcttcttta gttataccag aataacctgc taagataaca
    14521 tctggtttag aatttgatat tgcttcaaag ttaagtccat ccaaatcgtc aaataggtta
    14581 gctttaccat ttagttcttt gattttttct tctgtccatg gtaaaactcc tttatcagca
    14641 cttacaccgt aatttgcttt tgaaaatcca acaggaacta ttcctaaagc taatgctaca
    14701 tcatgatttc cccaagcaat agttgcaact ctttcaggtt ttttatctaa tatagtttga
    14761 ccgaaagcat gatctaaaac tattttatca ggcgcatgct ctttagaagt attttcttca
    14821 tttttaacag aattagaaga acaagcgcta aaaactatac acatagctaa aatagctatt
    14881 agaaaaaatt tgtttttcat aaaaactcct taaacatatt tcaagtctat tgtatcgata
    14941 ataattatca ttgtcaatag atacagttac aaatttaata atataatttt ttcaaaaaag
    15001 gatctagttt ttatttttag ttaaattatg tctatatttt tcattaactc atcaataaaa
    15061 atttgtttgc taatatctct ttcttctgat tttgtttcaa ggattattgc tacatcattc
    15121 atatttttag gtaaatacca accatctggc ttatctgaat atcccttgaa gcctaattga
    15181 ttaaaagtag ttatttgacc agtaccttga ttgatgtttt cttcaacttc attaaagcct
    15241 atacttctct tgcataatcc ctaacttgat cttctgtcct taaagtcatt ttctattcct
    15301 cgtcactaaa attatcttca aaactaataa tatcattagg agtgcaagat aaagccttac
    15361 atattctttc taaattctta aatgtaattg gtttatcctt tcccatttgt gccataacat
    15421 ttgttgtaag tcctgccata gctattacat ctgttttctt tagtcctttt tttgctaact
    15481 gtatccataa tggtttatag ttaagtgcca taatatccct ctttttttct tcattagatt
    15541 tatttaatta tagcataaat attgatttta ttcaatctta cattgattta gtgatttgtt
    15601 ttagagaatt tgttgtgtta ttccgtcctt attttgccat aaattgtttt aagtgggacc
    15661 tcttatcctt accattttta cctcctaatt ttgagtataa aaaagacgat agagttttta
    15721 atttctatcg tctgagattt acatattaaa ttttcatcac aaaataagac tctttaaaga
    15781 atctttaaat tcattggtat gctgcttaca atatccatta ttaaaatgga tattgtaagc
    15841 agcataccaa ctatttattt tttgagtttt aaactttggt agaagtcttg aactccttat
    15901 atttacataa ctatttgcct ctataactgt tatgacacga aaccaacaag caagttcaag
    15961 cacctccata tctttattca aatgaggact aagatattca caaactttat cataaacctc
    16021 tttatctttt ttcataaaag gggcatacaa cttagcaaat ttatcctaaa attttttgtt
    16081 gcctttatca atcatttcaa cgctccttta aatataaaaa tgatcctatc aatctttata
    16141 ttgagcctat tttctaattg ataccttgca agaaaggaat aatagctgtt cctataccaa
    16201 gtaggaatgt aataaatgca gaaagtcata tactgtcatt cttttctatt aaatcatttt
    16261 gaagtgtctc aaagcatcca tgatggcttc ttctttttca ggtgtacact gtggaataat
    16321 ttgtttatcc tttttagact tgttgtaatg ttctcgtaat tctattccac atttcttttt
    16381 tatctgtgca atatataatg tcgaaacttt taattcaaat ttattccaaa catattcttt
    16441 gatttgagca tatgttgctt tgctctccgc acttgtcaaa tccatctcat ccagctcaat
    16501 ttcaacactt atgtgcttat cgacatcaag tttggacaaa agtgctaccg tctcgacgtg
    16561 atgcgtttga ggaaatagat ccaccggctg gactttcttc aattcatatc ccaattcttg
    16621 gtagagtttg atatcacgcg ccatggttgc gacattgcag gagatatagg cgatgcgatc
    16681 ggctcctgtt tgggcgcttg ctttgataaa gctttctgtc aagcccttgc gtggaggatc
    16741 aaccaagata acggttggtt gaatcccatc tttaagccaa ttcttcatag cattttcagc
    16801 tgtgtcacag acatagtggg cgtttgaaat attgttcagc tgagcatttt ttttactatt
    16861 ctcaaccgct tctggaatca gttcaacacc gtagacttct ttgacatgct tggcgactga
    16921 taaaccaatg gttccaatac cagaataagc atcaataacc acgtcatctt tttttaactc
    16981 tgcaaagtca atggctgttt gatagagttt ctccgccatt tcagtattga cttggtaaaa
    17041 ggctgggcca gcgatttgga agtcatttcc caacatctgg tccgtaatat agtcttgacc
    17101 ataaagagtg cgccactcct taccaaaaat cgcattggta ttctggtcgt tgatattttg
    17161 catgacagac acaatctctg ggaactgctt gataacttgt tcaatcaatt ggtcaacacg
    17221 aaaaactttt ggacgagttg tcaccaaaac gaccatgatt tgtcctgaat agtgaccacg
    17281 acgcaccaca agattccgaa tcaatccaga ctgttccttt tcgtcataag gttttaaatc
    17341 aaaacgacgg agcaggcctc gaagagctac tacgacttgg tcaatgacag gatcctggat
    17401 aaagaaatct tcaaggggca tgaggtcgtg cgaattctta cggaaaaatc ctgtttccaa
    17461 gacaccattc actcgacgaa cgggcacctg cgccttattg cgatacttga ctggatgttc
    17521 cataccaagc gtttcagcaa cttctacatc tgcaattcca gcaatcttgt agagactgtc
    17581 cttgacttgc ttggttttaa acttgagctg ttctggataa gaaaggtgtc ctaaatccgc
    17641 gattcctgaa cgcaggtaag ccaaatctag atcttgatta cggtgtggtg actggacaag
    17701 gtatttttca acttttccaa agccaatctt tttattgacc ttgaggacac gcatgagaat
    17761 tttttcactc ggtaaagcat tctctacaaa aaagaccaaa ccatctacct tggcaactcc
    17821 tgccccttca tgggtcaagt caacaatttc aacttctaca atatcatttt tctttaacat
    17881 tcttttctct ttctattggc cgacaaaaaa gacggtaacg ttacggttac catccattat
    17941 accatgaaat ttcttaagaa ccaaaactct tgaagaagtt gacaagggct tgccagaggg
    18001 agcttaagaa gttaccaccg tcctctagcg ccttatccgc atcaaagtta aggttgatat
    18061 ttttaaaact gtcgccagct tgtgatacga tgctttgttt aaggtcattt agggttttag
    18121 tgaaatctgc attgctgagg atatcactct ttgagagatt caaggcaaaa ttgatgatga
    18181 tattgatctg gtttcctgtt atgacctgat caagtttgta attttttaag gtatcttcaa
    18241 caatcttgcg gatatcttct tctgtcagat ttcccttgct ttctttagct ttggcgagtc
    18301 ctgacttgat atcagctagg gcaacgttta atttattagc atcatagcct gatttgtcct
    18361 tgttttcagc attgatatct gacaaagctt ttagctcttc ttgagccaaa tctttattag
    18421 cttgtggcac cttggctcca ttagcctcta gcgaatagta aatccctgct aaagcacttt
    18481 ctcctgtaac tggaataggg gctgctacag tgattttggc atgttccata cccagcgtta
    18541 ctgctgcgtt tcggtacata tcctgagtca ccttagtgat attttctggt gtttcaatct
    18601 tgacctcaag tggcgatttg tcacctagct tttgaatctt ggctgatgaa tacaactgta
    18661 agctagagtc attggccaca ttcatgattt tagaataaac atcaggtgtc atggtcttga
    18721 gttctttggt atctgttgag gcattgtagc ccagtttttt aagagtttga tttttttggt
    18781 cttcagatag ggaggaacct aggacatatt caggttggac ataggtttca tcgataactt
    18841 tttgaacatc tgttgctgca tggacgctat tcatagctgt tactgcccac aagaccgcag
    18901 cactagtcag aaagagtttc tttctcatag ggaatttcct cctttacttc tttatagtaa
    18961 tatatctatc ttaaagaaaa cttataacaa aaacacctgg tctagccaga tgttgaaaag
    19021 agagtgaaac atttgatgat gtaaaggtta agtcgtacct gtctagaata ataataattt
    19081 cctccattta catagagttc agcaccgtga aaaatggaaa tggggtgaat ataactataa
    19141 gtctttccag tcgtattacc aagcaagggg gcaacagtct cacgagagta ctgtttggct
    19201 agagccaagg tattttcctt gccattttgg gcgataaaat cgatataggc aggtccaaaa
    19261 ttataggctt gaacagctgt ccagatatct acacccttct tctgcgccag atagagattg
    19321 cctgtcagag tttgaatgcc ttgccgaatg ctagaggcat tatcattgat ggtgttggtg
    19381 gaaccacttg cagactcact agactgcata acatcgcctt cttttccttt tgtttcagta
    19441 taaatcatag caagcacaag ctcttcgttt gctggggtgt ctttttcact caagatttct
    19501 cgcaccatgg gttgataggt catgacttgt ttgacatctt gatgaacgcg gtaagcttta
    19561 tagccagcaa aaaggaagac tgctagtaca agcactcttc gaattcgttt aaacattatt
    19621 tactttggat atcctcgata tttttgatta agatagagta ggttccattt tcgttttgga
    19681 taaactcaac agactcggcg tcttgataga cgttattggg aacgatgagc tcaattccat
    19741 ttgataagga gagtttttgg ttttcaaatt tctttaattg gcgacttgca tcaatttcat
    19801 caaattgaac aggttctggt acggcttctt tgacttggtc aataaagctc aaacgagccg
    19861 tcagattgtt gtcaaaaagg tcattagcca atttctcagg tgacaattca ttgctttctt
    19921 ctaggttgtt gaaaatcgct gatttgacct tggattgaaa ttgaaaatca tctgtgttaa
    19981 aagattcagc aattctctgg gctgtttttt ccagttcctt gatagatttt ttaggagaaa
    20041 tcttaggagc gacagcaaga agattatctg aaaaatagtt caaaaaagtc ccgttgtact
    20101 tgattcgttt ttcaatcagg tgatacttgc gactctgaag attgaccacc aaggcctcgt
    20161 cagcacccgt tccaaatcca ggcaggttat tctgagtcag cttgattgga ttatcaactt
    20221 ctcctccgag gtgggtcaag gtctcccgca gggcaattcg caagaaagcg aaatgttcta
    20281 caccttcttt agaaaattga acaaaaatca agtcattggt cttgagattt tcagaaatgc
    20341 taaactcctc tttccagaga ttagccagcg ttactgatgt ctccaacaaa tcgtctgtaa
    20401 tatgattgaa gaagggattt tcttcttcga aaatcccagt cttggcttca tctgaataca
    20461 catgttcaat ttttttacgt aggtattctt cgatttttgg agtaatattg agaaacttat
    20521 ctgctaagaa cagctcggta tcatccggac tgaactggtg aataatggct ttcttaatat
    20581 aaatgtccat aaaagtttta ttcctcgtat aatgggaagg catctgtcaa ttctttgact
    20641 gcacttctca cttcttctaa tacagcctca ttttctgaat tcttaagggt tttaatgatg
    20701 agttcagcca ctttgcgact ttcttcttca ccaaatccac gtgcagtaat agctgctgct
    20761 ccgatacgaa tcccacttgt cttgaatggt gacaaggttt cgtaagggat tgaattttta
    20821 tttagggtaa tattgacttc atccagcaag ttttgagcaa cttttccgtt ttctacaacc
    20881 ttagtcacat caacaaggaa gagatggttt tcagttccac ctgaaataat acggaaatca
    20941 gggtcttgca agaagacatc tgccatagcc ttgctgttct taattacatt ggcagcatat
    21001 tccttgaaag ctggatccaa aacttctttg aaggaaactg ccttagcagc cacaacatgc
    21061 tccaaaggac caccctgaat accagggaaa atagctgaat tgattttctt agctaaatcc
    21121 tcatcattgg tcaaaatcaa accaccacga ggaccacgaa gggttttgtg ggtcgttgtt
    21181 gtagtgatat gagcgtatgg cactgggctt gggtgaagac cagctgcaac caagccagcg
    21241 atgtgggcca tatcaaccat aagcttagcc ccaacagcat ctgcaatttc acggaatttt
    21301 gaaaagtcaa taatttgaga ataggctgaa gcaccagcta caatcagttt tggttttact
    21361 tcttgggctt gtttcaagat agcatcaaag tccaaaagtt ccgtttcagg atccacacta
    21421 taggaaagaa agttgtaggt ttgaccagag aagctaactg gagctccgtg ggtcaagtgt
    21481 ccacctgctg ccaaatccat tcccataacc gtatcacctg gctcaatcaa ggacatgtaa
    21541 gccgcacagt tagcttggct tcctgaatgt ggttggacat tggcaaattt agcaccgaaa
    21601 atttcttttg cgcgttcaat agcaagagtc tctacaacgt ctactacatc agttccacca
    21661 taataacggc gtcctgggta accctcggca tatttatttg tcaagataga cccttgagct
    21721 gccataacag ccttggaaac tacgttttcc gaagcaatta actcgatatt attttgttgg
    21781 cgttcttctt ctttggcaat agcattccag agatcagcat catatgcttt aaaatcatct
    21841 ttgtcaaaaa tcataggtct tctcctttat tgtgtgacta gtccattagt ttgattttac
    21901 aataagaaaa tcaaactaaa agatgcgaat aaaccgtttc tgcattttat cacaagtata
    21961 gccaactttt tcataaaatg catgagcacc cagacgatga ttggcagaat ttaagcggat
    22021 aaacccataa ccacatcttt tggcttcttg ttccaaccct tgtagtaaac ttttaccgat
    22081 accttgacct tgcgcttgag gtgaaactgc taaagctaag atattaaatc ctgctttgga
    22141 atagagtgat tcgtaaactt cagcgtggac atatccaagt aagacatgat tagctgcatc
    22201 ctcatagcca agtaggaaat gatgggaatc ctgagacagt ctagctagtt ggctagccgt
    22261 ttcctctgga ctaaaagtat aacccaaagc ctcttggttg atgtcacata tcgctttcac
    22321 atctgtttct tgcaaatctc ttagcatttc aagcctcctc aaaagaaatc tctggcaacc
    22381 gagcaagaat atcttctcgt ttaattgcgc cttggcgtaa gattttcacc ttgtctccag
    22441 acaaatccac aatagttgaa tcctgtccag ttagaaaagc atcgtcttcc agacccagaa
    22501 cctcttggtc aaaatccttc agaatttgtt caaaggttac accacttgcc tgacctgaga
    22561 tattggcaga cggcccaatc aagggacctg tctctcgaat taaatccagt gtgatagggt
    22621 gactgggcat ccgaaatcca atagttgcaa ggtcagaatt tacccaatag ggaactcggt
    22681 cattggcttc gagaataatg gtcaagggac ctggcaaaaa ggtctctaca agtttttgta
    22741 gataagctgg ctgattctta gaaaagtgca agatatcctc taaagaggca acattgagat
    22801 tgagcgcctt gtctctagga cgacgtttga gctggtaaac atggtcaact gctttttcgt
    22861 ctaaggcctt ggcaaaaaga ccataaaccg tctctgtagg cagaatgaca gctccaccat
    22921 tttccaactc ttgtctaatc ctgtccatca tcaaccacga ccatcctatc ttgaccaaat
    22981 tggtccttga gtgttcgaac tcttttttca ggaagatgtt tcctaaaaag ttcgggaaca
    23041 ctttgacctt gcttgtatcc aatttcaagg taaatcttac caccatcctt gagatagtct
    23101 tttgcatctt ccgcaattct acagtaaata gctaggccat cctcgtctgc aaagagagct
    23161 agatgaggct ccgaatgcaa aacattcaag cctacctctg actcatcttc acgagagata
    23221 tagggtggat tggatacaat tatatcatat ttttcagaaa tttctgcaaa acaatcagat
    23281 tttttaaaaa atatattaag attttgatcg ctagcattct ctgatgcaag ctctaaggcc
    23341 tcttgagaaa catctgctgc tgtcactgac caatctggtc tattttttgc tagagcgaga
    23401 gcaatagctc cactacctgt tccaatatcc agaactgaga gattcgtctc aagattttca
    23461 gttagaataa gctccactaa ctcctctgtt tctggacgag gaatcaaaac ccgttcatcc
    23521 acctttaaat gcattccata aaaatctgcc tgtccaatga tgtactgagc tggcttgtga
    23581 gctgctagtt gctggtaaat atcttctaca aattgttttt cttcctctgt tgtcacctcc
    23641 tgctggaggg caaaaataaa gtctgtaaaa gatagatttt tcagactacg atagacaaaa
    23701 gagaggcttt ccgcttcctc tccttgtctt atcaactctt cttcaaaatt tgaaaataat
    23761 tgagctaatt tcattatttg tttaattctt ctagtttttg tgtttggtca taaagcacca
    23821 aggcatccac aacttcgtcc aatttaccag acaaaatcgt atctagtttt tggagggtca
    23881 agccgatacg gtggtctgtg acacggtttt gtgggaagtt ataagttcgg atccgttctg
    23941 aacggtcacc agtaccgatt gtcgacttac gctcagcgtc ttgttcatcc tgagcaatct
    24001 gagcaaagtg gtcagcgacg cgtgcacgga taatcttcat agccttctcg cggttcttct
    24061 gctgggtacg ttcttcctgc atctcaacct tgatattggt tggcaagtga acgatacgaa
    24121 cggcagtcgc aaccttattg acgttctgtc caccagcacc agaggcgtga tagatgtcga
    24181 cacgaaggtc ttttggatca atgtcgtatt caacctcttc aacttctggc ataacaagaa
    24241 ctgtcgctgt cgaagtatga acacggcctt ggctttctgt cacaggaaca cgttgcacac
    24301 ggtgggcacc tgattcatac ttaagcttag agtatacaga ctgacctgaa accatagcaa
    24361 ccacttcttt aaaaccaccg acaccattca tagaggcttc catgacttca aagcgccaac
    24421 cttgggcttc cgcatacttt tggtacatag ttagcaaatc tccagcgaaa agtgccgctt
    24481 cgtctccacc agctgctcca cggatttcaa ggatgatatt cttgtcatcg tttggatcct
    24541 ttggaaggag caaaattttc agtttttctt catattcttc tttttcagcc ttggcatctt
    24601 tgagttcttg cttggccatt tcttccaagt ccgcatctcc gcctgattcc ttaatcatct
    24661 cttcggcatc gacgatattt tgaaggactt gtttatactc acggtaggct attacggtgt
    24721 cacgattgga agcttcttct tttgaaagct ccataaaacg cttggtgtct gaaacgacat
    24781 cagggtcact cagcaattct cctagttctt cataacggtc ttctacagct tgtagttgat
    24841 catagatgtt cattttttct ccttatttct caattgttaa atcatagatt gctactactt
    24901 cattctcggc tatttcccca gtttctttaa atccataact gaggtaacaa aatcttgcct
    24961 gttcattttc tggttcataa gacaaccaaa gtttattgct taaacctgct ggcgctgttc
    25021 gaacatagtc tagtacttta tccataattg gtttaaaata tccttgattt tgaaaattcc
    25081 tatcaatcat aaaacgaaat agtaaataat ttccactact aattccgatc tttttatcat
    25141 aagctatcat cacaaaacct ataattgcat cattatcata aactgccaat gtagctacaa
    25201 aatctccatt tttagtgtag acgtatgctt cagctaaact aattgcgttg gttgcaatga
    25261 attgtttttg atattccttg acatccaaat ttaaaacatc aaaataattt tccattgtaa
    25321 catctcttag ttcaattgtc atagttttgc tccttgttag aggttatcat tggcgtaaaa
    25381 taatgtttac ggcaaactga gatataggtt tcgttaccac caatctggat ctgttctcca
    25441 tcgtaaacgg gcagtccatc ctgtgttcgc aacaccatgg tcgccttttt cttgcaatac
    25501 tgacagatgg tcttgatttc gtcaatcttg tctgctaaaa gcaagagata tttggaacct
    25561 tcgaacaatt cattgcgaaa gtcatttttc aagccaaaag ccatgacggg tatgtctaac
    25621 tcgtccacaa cacgagctag gtcgtaaaca tggtggcgtt taagaaactg ggcttcatcg
    25681 accaaaacac agtaaggttt ttctggtagg tctcggatat agccaaagat atccgttgtt
    25741 tcctcaatcg caagggcagg gcgtttcatg ccaattcgac tcgacacata gccaacaccg
    25801 tcacgcgtat ccagagccga ggtcataatg acaacacctt ttccttgctc ctcgtagtta
    25861 taggccactt tgagaatctc aatcgtttta ccagagttca tggtcccata acgatagtac
    25921 aactgtgcca tgtttcttgc ttcacgtcca tttctaaatt tttgctacat tctagtatat
    25981 cataattttc ttaagcttta aacggcaaaa tgtggtaaaa tggaagaaat caaaactagt
    26041 ggaggaagct attatgccat ttgtacgcat cgatttattt gaaggacgca cgctcgagca
    26101 aaagaaagct cttgctaagg aagtaacgga agcagttgtc cgcaacactg gagcccctca
    26161 atctgctgtc catgtcatca tcaacgacat gccagaagga acttacttcc cacaagggga
    26221 aatgcgtact aaataagcta gcttaagcag aattgcttag gctttttcaa tctccaagta
    26281 gcattcattg aagaaatatc ctaaatttgt tacaatttga aaagaaactt ggagaatttc
    26341 caagaaaaga gctattaatt aaaggaaaca ttatgattac acgtgaattt gataccatcg
    26401 ctgctatctc tactccacta ggtgaagggg ctattggtat tgtccgcctg agcggaacag
    26461 acagttttgc tattgcgcaa aagattttta aaggaaaaga cttgaacaag gttgccagcc
    26521 acactctcaa ctacggtcac attattgatc ctctgactgg taaagtcatg gacgaggtta
    26581 tggttggggc tatgaagtct ccaaagacct tcactcgtga ggatattatc gagattaaca
    26641 cccacggtgg gattgcggtg accaatgaaa ttctccagct agctattcgt gaaggggctc
    26701 ggttggcaga acctggtgaa tttaccaaac gtgctttttt aaacggtcgc gtagacttga
    26761 cacaggcaga ggctgtgatg gatatcatcc gtgccaagac tgacaaggcc atgaacattg
    26821 cggtcaaaca attagacggc tccctttctg acctcattaa caatacccgt caagaaatcc
    26881 tcaatacact tgcccaagtt gaggtcaata tcgactatcc tgaatatgat gatgttgagg
    26941 aagctactac tgccgttgtc cgtgagaaga ctatggagtt tgagcaattg ctaaccaatc
    27001 ttcttagaac agcccgtcgc ggcaaaatcc ttcgtgaagg aatttcaaca gctatcatcg
    27061 gacgtcccaa cgttgggaaa tccagccttc tcaacaacct cttgcgtgag gacaaggcta
    27121 tcgtaacaga tatcgctggg acaacacgag atgtcatcga agagtacgtc aacatcaatg
    27181 gtgtacctct caaattgatt gatacagccg gtattcgtga aacagatgac atagtggaac
    27241 aaatcggtgt tgagcgttcg aaaaaagccc tcaaggaagc cgacttggtt ctactagtgc
    27301 taaatgccag tgaaccactg actgcgcaag acagacaact tcttgaaatt agccaagata
    27361 ccaatcgcat tattctactt aataaaaccg acctgccaga aacgattgaa acttcgaaac
    27421 tacctgaaga cgttatccgt atttcagtcc ttaaaaacca aaacatcgac aagattgaag
    27481 agcgaatcaa caacctcttc tttgaaaatg ctggcttggt cgagcaagat gctacttact
    27541 tgtcaaacgc ccgtcacatt tccctgattg aaaaagcagt tgaaagccta caagccgtta
    27601 atcaaggtct tgagctgggg atgccagttg atttgcttca agttgacttg actcgtactt
    27661 gggaaatcct cggagaaatc actggggatg ctgctccaga tgaactcatc acccaactct
    27721 ttagccaatt ctgtttagga aaataagaaa aatccatgat ccttcattcg gtcatggatt
    27781 ttattgtctt tattagtaat ctggtcttaa gacccctgtt acagttgcct tagttgcttc
    27841 gtagtcgcca tctacgacaa ccttgataat gcgtttggca tcttcttctg gtgctggaac
    27901 aagaggtaga cgagtgggtc cagcttcaaa tcccatatag ttaagaattg ccttaactgg
    27961 agcaggactt ggataagaga agagagcatt aaccttagga atgaatttac gctgaattgc
    28021 tgcggctttc ttcatatcgc tttctgcaat ggcagtaaac atctcgtgca tttcatcccc
    28081 atttgtatga gaggcaacag aaataacccc atccgcccca aggttcatgg catggaaagc
    28141 atctccatcc tcacctgtat aaatcaagaa ctcttcaggc ttgtgctcaa tcaagtaagc
    28201 catattagcc aagctagtac attctttgac accgataata tttggatggt cagccaagcg
    28261 aagcatggtt tctggagtca attcgacaac tacacgccct ggaatgttat agataataat
    28321 tggtaggtca gaagcatctg caatagtctt aaagtgctga tacatccctt cttgagaagg
    28381 tttgttgtag taaggaacaa tagcaagccc agctgcgaaa ccaccaaatt ccgctacttc
    28441 tttgacaaac tcaatagagt cacgcgtatc attagtacct acacccgcaa tcaaaggaac
    28501 gcgtccattg acaacctttt gtacagccgc aaacaactcc aactcctcat cgtgggtcaa
    28561 agttggactc tcagcagtcg ttcctgcgag aagaattcca tccgtatgat gggccaataa
    28621 atgctcaatc aaggctggaa tagcatcaaa gttaatggaa ccatcctcat ggaagggggt
    28681 aataaaggct gtaatgattt tacattcttt taaatcttga taagacacga aaacacctct
    28741 ctatttcaaa gaaggagttc atctgaactc ctaaacgata tgactatttt aattcaaatt
    28801 tcaattcggc tgttggacga accaatccac gttcatgaag agtttcagca atctgaactg
    28861 agttccaagc agcacctttg agaaggttat ctgaaacaac ccacatgtga attccttttt
    28921 ctgcatccaa gtctttacgg atacgaccaa caaaggtatc acgcgaacca actgcattga
    28981 tagcttgagg atagatttga tgagctacat catcttcaag aacagcacct gggaaggctg
    29041 cgatagctgc ttttacttct tcgattggag ccacttcttt tgtttcgata taaacagact
    29101 cagagtgagc tgacaagact ggaatacgca cacatgttgc agatactgca atgctatcat
    29161 cttccataat tttcttagtt tccttggtca tcttcatctc ttcgtacgtg taatcattat
    29221 cagtgaaaac atcaatttgt ggaagagcgt taaaggcgat aggataatgt ttcttgtcac
    29281 cacctgaagg caagatttcc gcatgcaaat cacgtggttt cacaccatca ttcaaaacct
    29341 cacgaagttc acgttgtgtc tcaagaattg ctcccatacc agcacctgaa acggcttgat
    29401 aagttgaaac aatgatacgg tccaagcccc atttttggcg aaccggctca agagccacca
    29461 tcatttggat tgttgaacaa ttagggcagg caatgattcc gttgtgagca tcaagtgcat
    29521 gagcattgac ctctggaaca accaaaggaa catctggatt ttgacggaaa taagatgtat
    29581 tatctactac taccacgcca gcttttactg cgtatggtgc atacttagct gatgtagaac
    29641 tacctgctga aaagagagca atatcaactc cttcaaaagc tgtttcagtc gtttcttcaa
    29701 ttgtaatatc ttgatcttta aatttcaatg acttacctgc tgaacgtgca gaagcaaggt
    29761 aacgaatttt atcgattgga agtgttgatt cttccaacat ttttatcatc tgagcaccga
    29821 cagcacctgt cgcgccgact acagcaactg tatatcccat aaataacctc tttcggaatt
    29881 ttctaaaaat ttctataata gaagtattat actacttttt ccatgaattg caaagctttt
    29941 tcatcatttt ttggaaaata aaaatcccag tcgctagact agggactaag aggcatcttc
    30001 atgtgatgag caggttcaca caactcatca aggtccgctc ctgcgttatg acctccttat
    30061 gctcaatagt agtccgaaga ctacctatcg actcatcgca tattctatat tactagagat
    30121 acttgatttt gtcaataaga aattttttcg atcgagtata acaaaaaact ctcgtattca
    30181 agagtttccc tatacatatc atgctaattg ccgggattga accggcgacc tcatccttac
    30241 catggatgcg ctctgccaac tgagctaaat cagcttactt aagaagtata ctatattcag
    30301 aaaaacttgt caagtttcct tagaaatttt ccataggaaa aagccaggta agaactacct
    30361 agcttatctt cttctattta cttaaatcaa ttcgacgacc aattttacca ataataatcg
    30421 ccccaataat caatgaagca aattcaccga ttcctgttgt aaaccaagta aggaagaatg
    30481 gtaattctgc tacaatattt aactctgcag cgatagtaaa catggaaatt gaaaagagga
    30541 ttgaaaagaa gaaatgatct tttcgaatca atccgttaaa gaggtaatcc ttgctatatt
    30601 ttgcaaaaag ccaaacacct aaactgagga atactaaggt tgaaccacca ccaacaaaga
    30661 catctagcag tccgaagcta aagaaattag caatcataca accgatggta actccgatga
    30721 tgtacttagg attgtaaaaa gccataaagt tcatcatttc tgaaatacga aactgataag
    30781 caccatagct gatggcattt aggggcggtg tgacagtcaa aacgacgtag atagcagcga
    30841 cgattgcaat atctgcaaca tcacgaatag ttaatttttt catcttttct cctttggcgg
    30901 ttgcccgcgt gtaatatgct tggtgaaaga agctaagcac caagggttgc tttattcaac
    30961 cctactagta tagcacaata gcctgcttta tgctatactt aacacatgaa aattcctatt
    31021 caaaaatttt ttaacaatga aatcttagcc tatctctttt ttggccttgc gacaactcta
    31081 gtttcgattc tctcacgact agtcatttat caactaagtc atcaggaact cctggctact
    31141 gccctagcaa atattatcgg tatcctattt gcctttatca caaatgatac gattgtattt
    31201 aagcaaaaaa agaaaaatag acttatccgt ttagtgaaat tttctcttgc tcgcctttct
    31261 acttttctgt tagacttgtt tttaactttt ctctttgtaa cccaatttcc tcacattata
    31321 gggcaattcg taactgaaaa cattgataag ataaatgcta ttgaaacaat aattgcacaa
    31381 atattcatta ttatcatcaa ttatatcttg agcaaggcct atatttttag aaaataatgc
    31441 tccatttatg agccttttaa ttgccttcta taatgattta ggatacaatg aaacacgaaa
    31501 cattgaaagg aaaacagtat gttaaaaaat ctaaaatcgt tcttgcttcg aggaaatgtt
    31561 attgaccttg ctgtcggtgt tgtaattgcc tctgcttttg gtgctatcgt tacttcactt
    31621 gtaaacgaca ttatcactcc tcttatttta aatcccgctt tgaaagctgc taaagttgaa
    31681 cgtatcgctc aactttcttg gcatggagtc ggctatggta acttcttaag tgctattatc
    31741 aattttatct ttgtgggtac cgccctcttc tttattatca agggcattga aaaagcacag
    31801 aaactgactg gcataaagaa agaaaaaact gccgaaaaaa aaccaaccga attggaagtc
    31861 cttcaagaaa taaaagctct ccttgagaaa aaataatcga ttaaaaggat ctagcgcaaa
    31921 gctaaatcct tttttcttta ctctttgggt aacttgcctg ctttttcaag catttttttg
    31981 atcagataag gcatcttaac attctcccgc ccttttttct caatcagttt tttcacaaat
    32041 tctggcattt gtaaatcttc agattcagct aaaatgtttt tcgtctcgtc tgaaggaact
    32101 aactcatcaa aggtctcttc ttctgggaga aattccttaa actcttgatt ttcattgact
    32161 ctaactgtat tgaccaaagc atcaatcaaa cgagaatctg tatttggcat tggtgaacga
    32221 tggtagttta ccccaaattc ctggcataag tcataacatt ctacatcatt gtcaaacaag
    32281 acctcaatat gctcactgat gaaactaata ggtacaaaaa tataatggtc tggatgttct
    32341 gtctgttctc tgagatactc caaaacaaag gatcaccaaa gtccaaggca aaaatgggca
    32401 cactatgggc tgaaaagatg actttaaaac tgtcttgctt tacttcttct tttaaaatct
    32461 tagcaatttc atctgcccaa tagtttaaga gcacttcttc ctgataccag tccttaatga
    32521 ccaaaaattg aatttgtttg ctttctaaaa atttttcata gcccatgaca gagtagaaag
    32581 aataatgggg ctccaaaatc aagcaaatac actgttcaat tccgtctgct tccatttgac
    32641 cgatcacatc tggaataaag ggactggaaa acttattagc aaagtagaca ctgtattcat
    32701 tccccagcct agcttctacc aaggtaacct cttgacgggt aattttttgc agaggcgtgc
    32761 ctccaattcg tacataatta tcatagagag tctgaatctc gtggtcttgg ggtctcaccc
    32821 cacgacgaat atttgtgaaa aaatcagcta caccttcaaa ggtaatctct tctggtgaac
    32881 cgaaggtcat cattaaaatt gcttttttca tgactgcttc cttgtgatgt ttttatcaag
    32941 tttattttat cattaattca tcgataagta aacgctaaca tagggacatt ctcaatcttc
    33001 tgtcttttgt ttttctcttc tttctatgat acaatggaaa aaataaattc aaaaggagtt
    33061 tttttatgac ttatccaaat ctcttggacc gcttcttaac ctacgttaag gtcaacacgc
    33121 gctctgatga acactctact actactccaa gtacacagag tcaggttgac ttcgcaacaa
    33181 atgtcctaat tcctgaaatg aaacgtgttg gactgcaaaa tgtttactat ctaccgaatg
    33241 gttttgctat tggaaccttg ccagccaacg atccgtcttt aacacgtaag attggtttta
    33301 tatcgcacat ggatactgct gattttaatg ctgaaggagt caatccacag gtaattgaaa
    33361 actacgatgg tggtgtgatt gaactaggga attctggttt caaactcgat ccagctgact
    33421 tcaagagtct tgaaaaatat ccaggacaaa cgctcatcac aacagatgga acaaccttgc
    33481 taggtgctga tgacaagtca ggaattgctg aaattatgac agccattgaa tatctaactg
    33541 ctcatcctga aattaagcac tgtgagattc gtgttggttt tggtccagat gaagaaatcg
    33601 gtgttggtgc caataaattt gatgcagaag attttgatgt ggattttgcc tacactgttg
    33661 atggtggtcc actaggtgaa cttcagtacg agactttctc agccgctggt gctgaattgc
    33721 atttccaagg ccgtaatgtc caccctggta ctgccaaagg gcagatggtc aatgcccttc
    33781 agctagcaat tgattttcat aatcaacttc cagaaaatga ccgacctgag ttaactgaag
    33841 gttaccaagg tttttaccat ctaatggatg tgacaggtag tgttgaggag gcgcgtgcaa
    33901 gctacatcat tcgtgatttt gaaaaagatg cctttgaagc gcgtaaagca tccatgcaat
    33961 ctatcgctga taagatgaat gcagaacttg ggagctaccg tgtcactctc aacttgacag
    34021 accagtacta caatatgaaa gaagtcattg aaaaagatat gactccaatt accattgcta
    34081 aagccgttat ggaagatcta ggtatcacgc ctattatcga accaatccgg ggtggaacag
    34141 acggctctaa gatttccttt atgggaatcc caactccgaa tatctttgca ggtggcgaaa
    34201 atatgcacgg acgttttgaa tacgttagcc ttcagactat ggaacgtgca gttgatacca
    34261 tcattggcat cgtagcttat aaaggctaaa aagacgaggt agctcagcta cttcgccttt
    34321 ctttttattc tactggtttt tcttgatttc cagtagttgt agaagattct gttgtttcat
    34381 tttctgaagt tgattcagca ggtttagaat ctcttgtatt gcttggtttg ttttcgtcgc
    34441 tagcaatttc aatgttagat tctgcagttg cgtttggttg gttctcagca ctggtgttat
    34501 cactatttgc ttcagcattt cttgctggac ttgtttcttc acttgcgcta gcttttgact
    34561 ggatttgatg attcaaaact agaatagctt ttgtcgattc aagtaaagct gttttgtctt
    34621 tactcttagc agaaagttga tctaataatg catccacctt atcaaagtcc gcatcagatc
    34681 cattattact ttctaaattt tccttttctt gttgaagggc gctagcgata cgagtcaaga
    34741 catcttttac ctgactgttt acttcatcca agtctgcatc agccttgttt gtggcagctt
    34801 ttagattttc tacttcttct gccaaggatt gtctgattcc ttcttcatgg atttgttcca
    34861 agagttgatt taccttgctc aaaagacttt ctacttcttc cttgctatct gtcgcagatt
    34921 attggttgcc atctaccatg tactcctaaa acaggagagt tataatccaa gattacaagg
    34981 ccttacagaa ataagaaatc cagataagac aatgttcgtc caagacgcta ttcgcttcgc
    35041 acagcagcac ggattcaata tgctttaatt ttaaagttta ggtgtcaaga cctcttttta
    35101 gtgtgcccaa aatttagaga agtaatcaat caactaactt ttattttttt caaactttca
    35161 gtaaactgac ctaaagctaa ctcaatctgt ctttgtagat gcttctgcta tcagctagaa
    35221 gttgatctac ttttgccaag actgccttct catcaaaagt tccaggttga tagttggatt
    35281 gcagggatgg aatcttgttt ttcaaagccg cttcatatcc cttagtttga accttgatgt
    35341 agtgattgtg gtcgccatga ggaatcacaa aaccttctga atcttcactt ataattcgat
    35401 tggcatcaaa accatgacca tcttcttcct catgatggac atgtagtgac ggattactta
    35461 atacagaact agaagaactt cctacctctt ccgtgttaga gtgtgatggg ggattgttaa
    35521 gagatgactt aggaatatag tgatagtgat ccccatgtct tactatataa gcatcacctg
    35581 tatctctgac aatatcatta gggttaaaga catatgtggc tgctaattca cctgccgaca
    35641 agtcactctc aggaatgaaa tgatagtgac caccatgtgg tactatagta gattgaaata
    35701 gaatatgagc aaattgataa ggggatttta aagtaatttc taacaatgat ttagaaacta
    35761 tgatgtgcta ttctaaattc aactcactat atataaccat catcggtagt ataacgtccc
    35821 tgtaattttg ctacagatac ttctgcacta gctcctttat cgtctttacc atgttcttgt
    35881 ttttggcgat tgatttcatc ttttgttcgt acattttctg catgagcttg atctttaagg
    35941 taaacataat actttccatc taccttaata atatatcctc ccttaaccta actgacgata
    36001 tcttgatctt tcggctgata gttgggggct ttcattaata gctcttcact aaagagcgca
    36061 tcaaaaggaa ctttaccatt atagtagtga taatgatcgc catgagaagt tacataacct
    36121 tgatctgtaa tcttaataac aatttgtttt gcttgaattc cttctttttg actaacctag
    36181 tctggagtca aattttcagt cttcttagtg tctttattac tgtttacata tgaaacacga
    36241 tttttatctg tattggcctg ttagctatgt tggttcagag cataaacaca cagacttaag
    36301 gaaaggataa caacagatcc agctgctata tatttctttt taaatttcat aattacctca
    36361 tttctataat tatttatatg atgtcttcat tattaaatga ttaaataaat taattaacca
    36421 attaattaac tagtaaatat tccacctctt tttaagttgt atgtcaagaa attttatata
    36481 ttaataataa aatgaaattc tcccaaagtc agagttttat ttctaacttt tgagagaact
    36541 tcatttttga ttcagacttt ttctactgct attccttacg ctatgagatc agataaattc
    36601 ttttttatca cttctccact tggcaatctt aattcaatcg ttccatccat attgaatata
    36661 acactatcta agcctaatcc gtaactagct gtaaattttt ctaatttttc ttgtacagga
    36721 tctactgctg gagcttcctc taatgctgga tctaacatag ggtcactccc cacattccct
    36781 tctggattca acattccatt atccgttgag ttttctggtt ttacaggttt ttcgtttggt
    36841 gcctctggta aagaatctgc tggtttattt tctgttggtt ggttctcaac tgttccagta
    36901 gatacttttc cagtttcaga tggtttattt tcaccatttc cttgaggtgc ttctcctgta
    36961 aaatctgcca tattcttttt aatgacttct cccgatggta aatataattc aattgttccg
    37021 tccatattaa acaagacatt ttctagcttc atcccataac tttcagcaaa ttttgctact
    37081 ttttcttgta caggatccac tgtaggaact tcttctaacg ttgaatcact agtactgttc
    37141 ccagtttcag gaagcttttc tttttctacc ttctcactag tctttggttc ttctaccttt
    37201 tcatcaagtt ttgagttttc ttgtgcttta ttccttttaa attgtggtag aatacttggt
    37261 ttatcagttt gattttcttt ttccaagata ggtacttcca caatataagt cgattgattg
    37321 tccaaataag catttgccat gaaggttaca ggaattttat ttccggccgt tctggttgtt
    37381 ccttggttta atttcggaat cggtaattta atttcaccaa ctttatagtt attttctaaa
    37441 taagcatttc catgaaattc atcaaacact ctgactaaag catcagttcc tttaggcact
    37501 gcaaattgag ggttcactct taaataagta tcccctgcat ggaaaggata gaaaatcgtt
    37561 tgactggcca ttttgtaagc taaagaggtt ggaactgtaa atgtaccatc ataacttact
    37621 tctggataat cttttgaagc gatagtatac ttaaatgttt gtcctggtaa ataaggttga
    37681 tctaattcaa agtttgcaat attccctact ccttctccaa atactttacc agatactttc
    37741 tccaatactt ttccatctgg tgttattaat tttactagca tattgatacc taattttttt
    37801 tccaattcag gcggaaaact aaaagaaacg cgtttttgac cattggctag agtaaagttt
    37861 tgattattaa acgtactatt ttttaacaaa ttaacaacat tcgttaattc ttctccagta
    37921 taaactttat tcccttcttt tttagcaact ccttcttcgg gtttaaacag ttcatagtta
    37981 ctgtgagaat gaccaattcc aaccggttta tgttcatcaa tcggatctgc atgatggtga
    38041 tctccatgcg gataaataat cgcatttttt tctttattca cgacaatact ttcacgtttg
    38101 acaccatatt gtttcataat gccagcaatt ttttcttcga tttttttatc taaatctttc
    38161 atttctttgg cattacctgg ataatcctgt tcatgagatg acaaagaatc taatccatta
    38221 tgactagttt taacttcctc taaatgtttt tgcgcagcct taatttgctc ttctgtcaag
    38281 tccttcttga agaaataatg attgtggtct ccgtgactca tgacaaaacc tgattcatct
    38341 tcagcgataa tacgattagc atcaaatccg tatccatctt cttcatgttt ctcatgtgaa
    38401 gttcctggat tgattggaag agatggagaa ggtgttgcta gactattgtt tggaagagtc
    38461 ggttgcccaa tttgatttga ttttggaatg taatggaaat gatcaccatg tcttacaata
    38521 taagctgtag ccgtttcttc aacgatatct tttggattaa aaatataacc atcagatgct
    38581 gaagagagtt tcttacttgt cgttaaagaa gaaggattgc ttgaaagact gcctagacta
    38641 gacactactt cattaggttt tgcatttgta gaaactgtag aaccagttcc actgataggc
    38701 accattctgg caatcttttc ttctaaggca gaaagcttgc tgtaaggaat aaagtggtaa
    38761 tggtcgccat gcggaatcgc aactccattt ggtgtacgac tgataatctt agcagggtca
    38821 aagaccaggc catctgattc actgtaacgt tgggcgctag gtgaatcata gagttccttc
    38881 aaaagactct ggagattttc agatttattt gctggcttgc tagttgatcc ttttgctaca
    38941 gattgcgtgt tattgtcact agctgttgaa gaatagctta actgactcgg ttgcatattt
    39001 tttccagcca gatgtgcttt agctgctgct aattcactag cagataaatc gcttttggga
    39061 atgtagtgat agtgacctcc atgaggaacg atataagcat tacccgtatc ttcgataata
    39121 tcagctggat taaagacata accatcattt gtcgtatatc gtccctgaga ccttgctaca
    39181 gcaacattag agttaacctt ctcattatct ttgacatgtt cttgtttttg acgattgatt
    39241 tcatctttag ttcgaacatt atcagcatga gctgcatctt tcaggtagac ataatatttt
    39301 ccatcgacct tgatgatata accacccttg acttcattga caatatcagc gtctttaagt
    39361 tgatagtttg gatccttcat caagagttct tcactaaaga gggcatcata aggaactttc
    39421 ccattatagt aatgatagtg gtcaccgtgt gacgttacat agccctgatc tgtaattttg
    39481 attacaattt gctcagcctg aattccttct ttctggctaa cctggtctgg tgtcaagttt
    39541 tcacttttct gacttgactg gctgccatcc acataagaga cacgattatt gtccttattt
    39601 tcctgcgaac gatgctggtt tagtgcatag gcacatagac tcaaggatac gataacagct
    39661 gatccagctg ctatatattt tttactaaat ttcataaatc cctcatttca ataaatgatg
    39721 aagttttttt ctcaacttct tttactttat taaatagttt tctaaaccga ttatttaacc
    39781 atttaattaa ccagtaaata gtctactatt taaaattact tttgtcaagt ttctgttacg
    39841 tttttctaaa aaagagaagt aacacgaaag gttacttctc cataaaatat gctccattca
    39901 ttttactact gtataggagc cggttgactt tcttttaaca aagccaagag actatctact
    39961 tctgctgaaa tagtattatt atctttcgtt ccgagaagaa gactactttt tagaccagtc
    40021 aatgtctcca tagcattttg tctaatacta gaatctgtta ctttttctag caaggcctcc
    40081 gcctctgcta tcttagcgtt aataacagaa tgctctactt gaggaatttc agcctcatct
    40141 gtagtatctt cagcttcttc ctctgtctct tccgtatcag tgcttggttt ataaagatta
    40201 tctgctgaag gatttaaacc agcgtgattc tctttttcat cagattcagg gtgagttggc
    40261 tcacttactt catcatgttc cttatcttcc tcaggttttt ctgtctgagg tttctccgtt
    40321 tgattggtat cagcttgacc atttttgttt ctttgaacat ggtcgctagc gttaccaaaa
    40381 ccattatctg aatgcggacg ttcgtttgga tgttcgacat agtacttgac agtcgccaaa
    40441 agatcctcaa gagtataccc cttaggtgcc tcataaaggc cttcgtcaaa ccactcaaat
    40501 ttgatgttat ggtaatggtc ataatgaggt atgattaaac taccgttttt gacttctaca
    40561 gtatattg
//
LOCUS       DAVBOM010000013        40457 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBOM010000013 DAVBOM010000000
VERSION     DAVBOM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.013"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            1..69
                     /locus_tag="VQ878_000741"
     tRNA            1..69
                     /locus_tag="VQ878_000741"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31..33,aa:Gly,seq:tcc)
     gene            104..177
                     /locus_tag="VQ878_000742"
     tRNA            104..177
                     /locus_tag="VQ878_000742"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:138..140,aa:Ile,seq:gat)
     gene            260..349
                     /locus_tag="VQ878_000743"
     tRNA            260..349
                     /locus_tag="VQ878_000743"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:296..298,aa:Ser,seq:tga)
     gene            363..436
                     /locus_tag="VQ878_000744"
     tRNA            363..436
                     /locus_tag="VQ878_000744"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:397..399,aa:Met,seq:cat)
     gene            440..512
                     /locus_tag="VQ878_000745"
     tRNA            440..512
                     /locus_tag="VQ878_000745"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Phe,seq:gaa)
     gene            525..605
                     /locus_tag="VQ878_000746"
     tRNA            525..605
                     /locus_tag="VQ878_000746"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:559..561,aa:Tyr,seq:gta)
     gene            610..680
                     /locus_tag="VQ878_000747"
     tRNA            610..680
                     /locus_tag="VQ878_000747"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:642..644,aa:Trp,seq:cca)
     gene            695..767
                     /locus_tag="VQ878_000748"
     tRNA            695..767
                     /locus_tag="VQ878_000748"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:728..730,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="VQ878_000749"
     tRNA            781..852
                     /locus_tag="VQ878_000749"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="VQ878_000750"
     tRNA            862..945
                     /locus_tag="VQ878_000750"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            1052..2329
                     /locus_tag="VQ878_000751"
     CDS             1052..2329
                     /locus_tag="VQ878_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET3095115.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2405..3889
                     /locus_tag="VQ878_000752"
     CDS             2405..3889
                     /locus_tag="VQ878_000752"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET3095116.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3950..5230
                     /locus_tag="VQ878_000753"
     CDS             3950..5230
                     /locus_tag="VQ878_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3095117.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVAMA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5234..5854
                     /locus_tag="VQ878_000754"
     CDS             5234..5854
                     /locus_tag="VQ878_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3095118.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6020..7198
                     /locus_tag="VQ878_000755"
     CDS             6020..7198
                     /locus_tag="VQ878_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3095119.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATEATTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7711..8049
                     /locus_tag="VQ878_000756"
     CDS             7711..8049
                     /locus_tag="VQ878_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3095120.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8060..8428
                     /locus_tag="VQ878_000757"
     CDS             8060..8428
                     /locus_tag="VQ878_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET3095121.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8535..9179
                     /gene="pcp"
                     /locus_tag="VQ878_000758"
     CDS             8535..9179
                     /gene="pcp"
                     /locus_tag="VQ878_000758"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3095122.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9207..10064)
                     /locus_tag="VQ878_000759"
     CDS             complement(9207..10064)
                     /locus_tag="VQ878_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET3095123.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10194..11336
                     /gene="tgt"
                     /locus_tag="VQ878_000760"
     CDS             10194..11336
                     /gene="tgt"
                     /locus_tag="VQ878_000760"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET3095124.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11437..13254
                     /locus_tag="VQ878_000761"
     CDS             11437..13254
                     /locus_tag="VQ878_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET3095125.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13407..14558
                     /gene="nagA"
                     /locus_tag="VQ878_000762"
     CDS             13407..14558
                     /gene="nagA"
                     /locus_tag="VQ878_000762"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET3095126.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14721..15779
                     /locus_tag="VQ878_000763"
     CDS             14721..15779
                     /locus_tag="VQ878_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET3095127.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15930..16295
                     /locus_tag="VQ878_000764"
     CDS             15930..16295
                     /locus_tag="VQ878_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET3095128.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16371..17312
                     /locus_tag="VQ878_000765"
     CDS             16371..17312
                     /locus_tag="VQ878_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET3095129.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17260..18276
                     /locus_tag="VQ878_000766"
     CDS             17260..18276
                     /locus_tag="VQ878_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET3095130.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18278..18604
                     /gene="comGC"
                     /locus_tag="VQ878_000767"
     CDS             18278..18604
                     /gene="comGC"
                     /locus_tag="VQ878_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET3095131.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNVGA
                     NRKVND"
     gene            18597..19001
                     /locus_tag="VQ878_000768"
     CDS             18597..19001
                     /locus_tag="VQ878_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET3095132.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19006..19266
                     /locus_tag="VQ878_000769"
     CDS             19006..19266
                     /locus_tag="VQ878_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095133.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19229..19690
                     /locus_tag="VQ878_000770"
     CDS             19229..19690
                     /locus_tag="VQ878_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3095134.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19668..20081
                     /locus_tag="VQ878_000771"
     CDS             19668..20081
                     /locus_tag="VQ878_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3095135.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20218..20812
                     /locus_tag="VQ878_000772"
                     /pseudo
     CDS             20218..20812
                     /locus_tag="VQ878_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20873..21826
                     /locus_tag="VQ878_000773"
     CDS             20873..21826
                     /locus_tag="VQ878_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3095136.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKHLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21877..23067
                     /locus_tag="VQ878_000774"
     CDS             21877..23067
                     /locus_tag="VQ878_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET3095137.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23216..23587
                     /gene="rnpA"
                     /locus_tag="VQ878_000775"
     CDS             23216..23587
                     /gene="rnpA"
                     /locus_tag="VQ878_000775"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET3095138.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23562..24386
                     /locus_tag="VQ878_000776"
     CDS             23562..24386
                     /locus_tag="VQ878_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3095139.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24405..25391
                     /locus_tag="VQ878_000777"
     CDS             24405..25391
                     /locus_tag="VQ878_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET3095140.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25442..26065
                     /locus_tag="VQ878_000778"
     CDS             25442..26065
                     /locus_tag="VQ878_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET3095141.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26196..27653
                     /locus_tag="VQ878_000779"
     CDS             26196..27653
                     /locus_tag="VQ878_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3095142.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27676..27957
                     /locus_tag="VQ878_000780"
     CDS             27676..27957
                     /locus_tag="VQ878_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3095143.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28034..28519
                     /locus_tag="VQ878_000781"
     CDS             28034..28519
                     /locus_tag="VQ878_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3095144.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28536..29201
                     /locus_tag="VQ878_000782"
     CDS             28536..29201
                     /locus_tag="VQ878_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET3095145.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29205..30068
                     /locus_tag="VQ878_000783"
     CDS             29205..30068
                     /locus_tag="VQ878_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET3095146.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            30070..30774
                     /locus_tag="VQ878_000784"
     CDS             30070..30774
                     /locus_tag="VQ878_000784"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET3095147.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30953..32626
                     /locus_tag="VQ878_000785"
     CDS             30953..32626
                     /locus_tag="VQ878_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3095148.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32738..33829
                     /gene="ulaG"
                     /locus_tag="VQ878_000786"
     CDS             32738..33829
                     /gene="ulaG"
                     /locus_tag="VQ878_000786"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET3095149.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33943..35919
                     /gene="tkt"
                     /locus_tag="VQ878_000787"
     CDS             33943..35919
                     /gene="tkt"
                     /locus_tag="VQ878_000787"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3095150.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            36036..36335
                     /gene="yajC"
                     /locus_tag="VQ878_000788"
     CDS             36036..36335
                     /gene="yajC"
                     /locus_tag="VQ878_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3095151.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36381..36809
                     /locus_tag="VQ878_000789"
     CDS             36381..36809
                     /locus_tag="VQ878_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET3095152.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36811..37221
                     /locus_tag="VQ878_000790"
     CDS             36811..37221
                     /locus_tag="VQ878_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095153.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37520..40171
                     /gene="adhE"
                     /locus_tag="VQ878_000791"
                     /gene_synonym="adhC"
     CDS             37520..40171
                     /gene="adhE"
                     /locus_tag="VQ878_000791"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET3095154.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12275 a         7247 c         9106 g        11829 t
ORIGIN      
        1 gggtgtagtt tagtggtaaa actacagcct tccaagctgt tgtcgcgagt tcgattctcg
       61 tcacccgctt tgaactttgt tctttgtacc aagtttttga cttgggcgcg tagctcaggt
      121 ggttagagcg cacgcctgat aagcgtgagg tcggtggttc gagtccactc gtgcccatag
      181 tgtttagtcc attactaggg gattggaata ttatctgttc actaagagga cacgggcttg
      241 ttcccgtata aactattttg gaggattacc caagtccggc tgaagggaac ggtcttgaaa
      301 accgtcaggc gtgtaaaagc gtgcgtgggt tcgaatccca catcctcctt ttatattatt
      361 aacgcgggat ggagcagctc ggtagctcgt cgggctcata acccgaaggt cgtaggttca
      421 aatcctgctc ccgcaataag gctcggtagc tcagttggta gagcaatgga ttgaagctcc
      481 atgtgtcggc ggttcgattc cgtctcgcgc catttatata ttttggaagg gtagcgaaga
      541 ggctaaacgc ggcggactgt aaatccgctc cttcgggttc gggggttcga atccctcccc
      601 ttccatttta cgggcatagt ttaaaggtag aactaaggtc tccaaaacct tcagtgtggg
      661 ttcaattcct actgcccgtg ttaatagaat tatggcgggt gtggtgaagt ggttaacaca
      721 ccagattgtg gctctggcat gcgtgggttc gatccccatc actcgcctat tttatattat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagta tagtgttagg
      961 aacgttgtta ttcttcgttc cttttttata ttatttttgg tataattata gttattcaaa
     1021 ttttatttag attaagaaag tgtagggtag tatgtcttgt tctatcgatt tattaaaaca
     1081 tcggtatttg aaaaatatta aagaaaatcc tgaattgttt gtcggaattg agttggagta
     1141 tcctgttgca agtttagaag gggatgctac agatgttgaa gttataaagg atctatttca
     1201 ttatttagtt tctactttgg atctcaccgt agcaaaggta gatgattttg gcaatctgat
     1261 ccagttagta gatccgataa gtcaggatgc tattttattt gaagtttcct atacaacgat
     1321 tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc gaaaatcgtt tcaataatta
     1381 tatgaatgta attcagagaa agttagctga atcaaatcat gctattgttg gctgtggtat
     1441 ccatcccaac tgggataaaa atgagaattg tccagtggct tatccacgct atcagatgtt
     1501 gatggattat ttgaatttga gtagaaatat tattaaatca gatttacatc atttccctga
     1561 atatggtact tttatctgtg ggagccaggt tcagctggat atttcaaaaa ccaactactt
     1621 acgggtgatt aatgctttta ctcaaattga agcggctaag gcttatttat ttgcaaactc
     1681 tgaattttcg ggtgcggatt gggatacgaa aatttcaagg gatattttct gggaagaatc
     1741 tatgcatggt atctatccag agaatgttgg ggtcaatgct agactcctta atgatgaagc
     1801 tgattttttt gactatctaa atcattctgc gatttttact gcggaacgtg atgggcagac
     1861 ctattatttt tatcctattc aggctgggga ctatttggct acgtccgaaa tccaagcatt
     1921 tgctctgaat ggggatgagg ttattattta cccccaagag aaggattttg aaactcatcg
     1981 tagttaccag taccaagatt taacgactcg aggaacagtt gagtttcgta gtgtgtgtac
     2041 acagccactt gataggactt ttgcttctgc agcttttcac ttgggattat tggttaattt
     2101 agacaagtta gaagcttact tagaaacagc acctttcttt aaagtatttg gttatgatta
     2161 caagtcttta aggagacaat tttctaagaa aaatcttaca gatgaggaag aaactacgat
     2221 tattgaattt tccaaagact tactcctact agctgaggag ggactagtgg tgagaaataa
     2281 ggaagaaatg acctatttac agcctttgag agaagaattg agcctataat ttctcttata
     2341 aagggagaat tttctgaaaa atcatgatat aatggacgag actatagata aaggatagag
     2401 agtaatgaca ttagtttatc aatcaacgcg tgatgccaac aatacagtaa ctgccagcca
     2461 agcaattttg caaggtttgg cgacggacgg cggtttgttt acaccggtta cttatccaaa
     2521 ggtagatttg gactttgaca aattgaaaga tgcttcttac caggaagttg ctaagctagt
     2581 tttgtcagca tttttagatg actttacagc tgaggagttg gactactgta tcaacaatgc
     2641 ctacgatagc aaatttgata ctccagctat tgcaccatta gtgaaattag atgggcaata
     2701 caatttggaa cttttccatg gttcaacgat tgcctttaag gatatggcct tgtctatttt
     2761 gccatacttt atgacgactg ctgctaagaa acatggtttg gagaacaaga ttgttatctt
     2821 gacagcgaca tctggtgaca cggggaaagc tgctatggcg gggtttgcgg atgtgcctgg
     2881 tactgagatt atcgtctttt atccaaaggg tggtgtcagc aaggtacaag agttgcaaat
     2941 gaccactcag aatggtgaca atactcatgt tattgctatt gatggtaatt ttgacgatgc
     3001 gcaaacaaat gtgaagcaca tgtttaacga cgtggctctt cgtgaaaaat tgactaccaa
     3061 caagttgcaa ttttcatcag ctaactctat gaacattggt cgtctggtgc cacaaattgt
     3121 ttattatgtt tatgcttacg ctcaattggt taagactggt gaaattgtag ctggtgaaaa
     3181 ggttaacttc acagtaccaa caggaaactt tggaaatatc ttggctgcct tttatgccaa
     3241 acaaatcggc ctaccagttg gcaagctaat ctgtgcttca aatgacaata atgtcttgac
     3301 agacttcttt aaaacacgtg tctatgacaa aaaacgtgag tttaaggtaa caaccagccc
     3361 atctatggat atcttggtat cttcaaactt ggagcgcttg attttccatc ttttgggaaa
     3421 taatgctgaa aagacagctg aacttatgaa tgccttgaac acgcaaggac aatataagtt
     3481 gacagacttt gatgcagaga ttttggacct ctttgcagct gaatatgcga ctgaggaaga
     3541 aacagcggca gaaatcaagc gtgtttatga gtcagattct tatattgagg atccacatac
     3601 ggcggttgcc tcagcagttt atagaaaata ccaagcggtt actggagatg taactaagac
     3661 agtgattgct tcaacagcta gtccatacaa gttcccagta gttgcagtag aagctgtaac
     3721 tggaaaagca ggtttgacag actttgaagc cttggctcaa ttacatgaaa tctcaggcgt
     3781 tgcagtgcca ccagcagttg atgggcttga aatagctcca attcgtcaca agacaacagt
     3841 ggcagctgct gacatgcaag cagcggttga ggcttattta ggactttaag acagagggag
     3901 caaactcggt tgggaaacca actgagtttc ttttcatcag gaggagagat tgtttaagaa
     3961 aaataaagac attcttaata ttgcattgcc agctatgggt gaaaactttt tgcagatgct
     4021 aatgggaatg gtggacagtt atttggttgc tcatttagga ttgatagcta tttcaggggt
     4081 ttcagtagct ggtaatatta tcaccattta tcaggcgatt ttcatcgctc tgggagctgc
     4141 tatttccagt gttatttcaa aaagcatagg gcagaaagac cagtcgaagt tggcctatca
     4201 tgtgactgag gcgttgaaga ttaccttact attaagtttc cttttaggat ttttgtccat
     4261 cttcgctggg aaagagatga taggactttt ggggacggag agggatgtag ctgagagtgg
     4321 tggactgtat ctatctttgg taggcggatc gattgttctc ttaggtttaa tgactagttt
     4381 gggagccttg attcgtgcaa cgcataatcc acgtctgcct ctctatgtta gttttttatc
     4441 caatgccttg aatattcttt tttcaagtct agctattttt gttctggata tggggatagc
     4501 tggtgttgct tgggggacaa ttctgtctcg tttggttggt cttgtgattt tgtggtcaca
     4561 attaaaactg ccttatggga agctaacttt tggtttagat aaggaactgt tgaccttggc
     4621 tttaccagca gctggagagc gacttatgat gagagctgga gatgtagtga tcattgcctt
     4681 ggtcgtttct tttgggacgg aggcagttgc tgggaatgca atcggagaag tcttgaccca
     4741 gtttaactat atgcctgcct ttggtgtcgc tatggcaacg gtcatgctgt tggcccgagc
     4801 agttggagag gatgattgga aaagagttgc tagtttgagt aaacaaacct tttggctttc
     4861 tctgttcctc atgttgcccc tgtcctttag tatatatgtc ttgggtgtac cattaactca
     4921 tctctatacg actgattctc tagcggtgga ggctagtgtt ctagtgacac tgttttcact
     4981 acttggtacc cctatgacga caggaacagt catctatacg gcagtctggc agggattagg
     5041 aaatgcacgc ctcccttttt atgcgacaag tataggcatg tggtgtatcc gcattgggac
     5101 aggatatctg atggggattg tgcttggttg gggcttgcct ggtatttggg cagggtctct
     5161 cttggataat ggttttcgct ggttatttct acgctatcgt taccagcgct atatgagctt
     5221 gaaaggatag gaaatgcaaa aaacagcttt tatttgggat ttagacggga ctttattgga
     5281 ctcttacgaa gcgattttat cagggattga ggagactttt gctcagtttt ctattcctta
     5341 tgataaggag aaggtgagag agtttatctt caagtattcg gtgcaaaatt tgcttgtgcg
     5401 ggtggcagaa gatagaaatc tggatgttga ggtgctaaat caggtgcgtg cccagagtct
     5461 ggctgagaag aatgctcagg tagttttgat gccaggtgcg cgtgaggtgc tagcttgggc
     5521 agacgaatca ggaattcagc agtttatata tactcataag gggaacaacg cttttaccat
     5581 tctcaaggac ttgggggtgg aatcctattt tacagagatt ttaaccagtc agagtggctt
     5641 tgtgcggaag ccaagtccag aagcggctac ctatctgcta gataagtatc agttgaattc
     5701 tgataatact tattatatag gggatcggac tctggatgtg gaatttgccc agaatagtgg
     5761 gattcaaagt atcaactttt tagagtctac ttatgaaggg aatcacagga ttcaagcgtt
     5821 agcagatatt tcccgtattt ttgagactaa gtgataaaaa gattgtgtca gttttgtgac
     5881 agagacctaa caaactattt caagtaatct agtttgttac aaggaataga cagttctgtt
     5941 aaataggccc gagagggctt tttttctaca ttttttgtgt tatgatagac aggtactcat
     6001 ttgaaaggaa tttgaaggaa tgaagaaaag aatgttatta gcgtcaacag tagccttgtc
     6061 atttgcccca gtattggcaa ctcaagcaga agaagttctt tggactgcac gtagtgttga
     6121 gcaaatccaa aacgatttga ctaaaacgga caacaaaaca agttataccg tacagtatgg
     6181 tgatactttg agcaccattg cagaagcctt gggtgtagat gtcacagtgc ttgcgaatct
     6241 gaacaaaatc actaatatgg acttgatttt cccagaaact gttttgacaa cgactgtcaa
     6301 tgaagcagaa gaagtaacgg aagttgaaat ccaaacacct caagcagatt ctagtgaaga
     6361 agtgacaact gcgacagcag atttgacaac caatcaagtg accgttgatg atcaaactgt
     6421 tcaagttgca gatctttctc aaccaattgc agaagctcca aaagaagtag catcaaattc
     6481 agaagttgca gagacagtga ctgctgcaga agaagtggca ctatctacag actctactac
     6541 gccagaggga caaccagccg aaacaactag tccagttgaa gaagtagctc ctcaggcaac
     6601 gactctagct gagaagcagg aaacacaagt gagctctcaa accgagtcag cagtggaagc
     6661 aactacaatg ccagtagaag aaaaagcaac cgaagcaact acaacaagtt cagaagcaaa
     6721 agaagtagca tcatcaaatg gagctacagc agcagtttct acttatcaac cagaagagac
     6781 gaaaataatt tcaacaactt acgaggctcc agctgcgccc gattatgctg gacttgcagt
     6841 aacaaaatct gaaaatgcag gtcttcaacc acaaacagct gcctttaaag aagaaattgc
     6901 taacttgttt ggcattacat cctttagtgg ttatcgtcca ggagacagtg gagatcacgg
     6961 aaaaggtttg gctatcgatt ttatggtacc agaacgttca gaattagggg ataagattgc
     7021 ggaatatgct attcaaaata tggccagccg tggcattagt tacatcatct ggaaacaacg
     7081 tttctatgct ccattcgata gcaaatatgg gccagctaac acttggaatc caatgccaga
     7141 ccgtggtagt gtgacagaaa atcactatga ccacgttcac gtttcaatga atggataaac
     7201 ccgacttggt aacatcattt tgacgaatga gatctagctt tcgtgatagg aagcgattct
     7261 cgttcgtttt ttctttgtca tactcttcga aaatctcttc aaacaacgtc agttttatct
     7321 gaaacctcaa agctgtgctt tgagcaacct gcgactagct tcctagtttg ctttttgatt
     7381 ttcattgagt atcaatttga atggaaaatg gaaagttatc atcttgtaat gagttaagca
     7441 acattcttgc aatctatttt atagtagatt gaaactagaa tagtacacaa ctgcttctaa
     7501 aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgctctt atttcatttc
     7561 actatacttt atattataat tgactggtca aatattgata aatcaataaa aagagagggg
     7621 aagaaatgct agagattcaa gatttactgt atcaactccg cttgtctgag caagtgagta
     7681 cgcaattgtt tgaaaaagct tgggattagt ttgacacggt atcagatttt actgtttttg
     7741 ctggagcatt ctccttgtaa ccaaatggcg gttcaggagc gtttgaaaat tgatcaggct
     7801 gctttgacac ggaatttcaa gattttggaa acggaaggtt tggtggagcg tcatcgtaat
     7861 cctgaaaatc agcgggaagt attggtagag gctgcgaagt atgccaagga gcagttagtg
     7921 gtgaatcccc ctctgcagca tatcaaggtt aaggaagaga tggaaagtat cttaacagag
     7981 tttgagagaa cagaactcag ccgtttatta aataaattgg ttttgggtat tgaaaatata
     8041 gaaatttaag gagaaataga tgtcaattat tacaattatt ttaacaacga tcgttgcttt
     8101 ggagcatttt tacatttttt atttggaaag tattgccacg caatcagatg cgactagtcg
     8161 tgtatttaat atggaaaagg aagaattggc tcatccgtca gtaagttcat tgttcaaaaa
     8221 tcaagggatt tataaggctc tgctaggagt ctttctcttg tatgtcattt atttctcaca
     8281 gaatttagaa attgtgacta tttttgtctt atttgtgatt ggtgctgcga cttacggctc
     8341 tttaacagcg gataaaaaaa ttattttgaa gcaaggtgga tcagctattt tggccttgat
     8401 tagtatttta ctctttaaat acacttgaag gtcgatttta atctcgctaa tcctttttaa
     8461 tccagaataa gggaaatatg ttatacttgt ttttaagaaa aaagtctcat tgaattggtt
     8521 ttgaggagtt agaaatgaaa gtattagtga caggttttga gccctttgga ggggaaaagg
     8581 gcaatccaac tttggaggcc attaaaggtt taccagctga aatccatggt gctgaggtcc
     8641 gttggctaga ggtgccgaca gtttttcaca aatctgctca agtattggaa gaagagatga
     8701 atcgttatca acctgacttt gtcctttgta ttgggcaagc tggtggaaga actagtgtga
     8761 cacctgaacg agtggccatt aatcaagacg atgcacgcat ttctgataac gaagataatc
     8821 aaccgattga ccgtcccatt cgcccagatg gtgcttcggc ctactttagt agtttgccga
     8881 ttaaagcgat ggttcaagct ataaaaaaag agggcttacc ggcctctgtt tccaatacgg
     8941 cagggacttt tgtctgcagc catttgatgt atcaggctct ctatttggta gaaaagaaat
     9001 ttccatatgt taaggcaggt tttatgcata ttccttatat gatggaacag gtggtgaaca
     9061 gaccgactac tccaactatg agtttagtgg atattcggcg agggatagaa gcagcaatcg
     9121 gcgctatgat agaacatgga gatcaggaac tcaagttggt aggcggagaa actcattgat
     9181 agaaaaaagc ttgaggggaa aaaccttcaa gcttttggac gttttcgagc caatactgct
     9241 cggtaaaaca taattttagt gcattggata taaggtagga gtgaaaaact agcaatgcca
     9301 aaggtaatcc aattgaggaa gtaccaagga agaagctgta aatctaggac aaagtgctgg
     9361 aacttgtagc ccttcataaa ggaacggcta gtttttagga ttcgtcttgg tgggacctgt
     9421 cctaggtcta gactataaca gagaagaaat tccacctgtg aataggcata atactgtgga
     9481 atatagagga tatttcctac aatgatcaag atgagacttg caagaaagta gagtccaaag
     9541 accatgagga aacgctcggt ttcaactgat gagagatcta gatttggaaa ctcaggatgt
     9601 agggtgacga attttttggc taaaaagcta ctataaaaga ggaggtaaat cccaagtaaa
     9661 ttagggatac tccataaaaa gagatagaaa cgtttgagaa gtagggtcaa aaaggtttga
     9721 gaaaagcgct cctcatcaaa gagagctagg ctgtttttta cagatggctc cgttttagaa
     9781 tctttcatga gtgtcagtgt tgcatagacg gaactggtca aaagaatagt cccgataaag
     9841 gagactagta gaggaaagag gtaggtttga agtatttggc caagtatgct gaaaaatggc
     9901 tgttctaaaa cagtcccgtg gatccgagat aagggattaa gaaaaccaga taagatgacc
     9961 agcatactgg gaaggatata gaggagaaag agacgggggg tgtcagcctg aaaatgtttt
    10021 gactcctgac gaattgtttt taaatcaatt tttggatagt tcattctctt attataccat
    10081 agttcttata catagttcgt gacagttcct actttttttg ataaaatcat acagtgtgtc
    10141 cttgggcaca ctgtatgaac tgggactgtc tttcccagct tcggaggtaa aaaatgtcag
    10201 attcaccaat caaatatcgt ttgattaaga aagaaaaaca cacaggagct cgtctaggag
    10261 aaatcatcac tccccacggt acctttccga cacctatgtt tatgccagtt gggacacaag
    10321 ccactgtcaa aactcagtca cctgaagaat tgaaggagat gggttcggga attatcctat
    10381 caaacaccta tcatctctgg cttcgccctg gagatgaact cattgcacgc gctggtggtc
    10441 tccacaagtt catgaattgg gaccagccta tcttgacaga tagtggtggt tttcaggttt
    10501 attctttagc agatagccgt aatatcacag aagaaggagt aacctttaaa aatcatctaa
    10561 atggttctaa gatgctccta tccccagaaa aagccatctc tattcagaat aatctgggtt
    10621 cagacatcat gatgtccttt gatgaatgtc ctcagtttta tcaaccttat gactacgtta
    10681 agaaatcgat cgagcgtacc agccgttggg ctgagcgtgg tttgaaggct caccgtcgtc
    10741 cacatgacca aggtttgttt ggaattgtgc aaggtgcagg atttgaagac cttcgccgcc
    10801 aatcagctca cgatcttgtc agcatggatt tctcaggcta ctctatcggt ggtttggcag
    10861 tgggagaaac ccatgaagag atgaatgcgg tcttggactt tacaactcaa ctgctgcctg
    10921 aaaataaacc tcgttatctg atgggtgtgg gagcgccaga tagcttgatc gatggggtca
    10981 ttcgtggggt ggatatgttt gactgtgtct taccgactcg aattgctcgt aacgggactt
    11041 gtatgaccag tcaaggacgt ttggttgtga aaaatgccca gtttgctgag gactttacgc
    11101 cactggatcc tgagtgtgat tgctacacat gtaataacta tacacgcgct taccttcgtc
    11161 acctgctcaa ggctgatgaa acctttggta tccgcttgac tagctaccac aatctttact
    11221 tcttgcttaa cctgatgaag caagtgcgac aagccatcat ggatgacaat ctcttggaat
    11281 tccgtaagta ttttgtggaa aaatatggct ataataagtc aggacgtaat ttctaaaatg
    11341 gaattgatat aagctaaaaa tcctaagttt tctcttagga tttttcttct ttttttgata
    11401 gaataaagtg tacaatgaaa ggaagaataa actcgtatgc gcattaaatg gttttccttg
    11461 attaggatta taggtttact tttggtactc ttgtatcact tctttcagac gatctttcct
    11521 ggaggatttt tcggggtaga tgtctttttc acattttcag gtttcctgat tacagctcta
    11581 ctcattgaag aattttctaa gaacaatgag attgatttga taggattttt tagaagacgc
    11641 ttttatcgga ttgtgccacc tgtggttttg atggtcttgg tgaccatgcc ttttactttc
    11701 ttggttcgcc aagactatgt tgctggaatt ggtggccaga ttgcgggcgt cttaggcttt
    11761 atgaccaact tctatgaact cttaacaggt gggagttatg aatctcagtt cattcctcat
    11821 ttgtttgttc ataattggag tttggcagtt gaggttcact actatattct ttggggattg
    11881 gcagtttggt tcttatccaa acaagctaaa tcaaatggtc agttgaaggg gatgatcttt
    11941 ctcttatctg ctactgcctt cttgatcagt ttcttctcca tgtttattgg tagttttcta
    12001 gtgacctctt attcctctgt ttatttctcc agtttaactc atgtctatcc attctttttg
    12061 ggaagtatgt tagcaactat tgtaggcgtt cgtcagacga cttccctcgt caagcagttg
    12121 gataaaatct gggatttacg aaagacttta gtagtttttg gaggaggctt tggtttccta
    12181 gttcttttga ctttctttgt caaattcact tatctttttg cctatcttat cggcttcttg
    12241 cttgccagtc ttgcagctct tgccatgatt ctggcggcgc gtgtcttaca tgaaaagaca
    12301 catcatatac aggagccgaa gattatcagc tttttagcgg atactagcta tgcggtttat
    12361 cttttccatt ggcctttcta tatcattttc tcacagttga catcaaatct tcttgctgta
    12421 ttactgactc tgatttgttc ttatggcttt gccagtctgt cattttatgt attggaacct
    12481 tggattgcag gcaagaacac acctatttta caaactcttc gtcccctgcc ttatattcac
    12541 gcaattcttg cagcaggtac aggaatcttg accttcattg tctgcatggt gaccttgttg
    12601 gcaccacaag tgggagcgtt tgagacagac ttgactgtca atggcttgaa gcaagctgca
    12661 acaaatattg gccagaccaa ggtgatggca gaacgggcag atgcaaacag tttgggaatt
    12721 gctgatggca ctatgttaat tggtgactca gtggctttaa gggcaaatac agcactacag
    12781 acagctcttc ctggagcaca gattaacgcg caggtcagcg taacaaccaa gaccgcaaat
    12841 gaaatcatgc taaataatag ccagaataaa tttttaccta agacggtggt cattgcgact
    12901 ggggtaaata atcctgagaa ttacaaggat gactgggaca gtatcgtgaa aaatcttcct
    12961 aagggacacc atatgatttt ggtgactcct tatgagggtg ataagacaaa agagacctat
    13021 gccatcgttg agaaggctgc tgcctatatg agagaattgg cagagaagac accttacatt
    13081 acgatagcag attggaatca agttgcgaaa gagcatccag aaatttgggc tggaacagac
    13141 caggttcatt tcgggagtga gagtagcact atcgaagcag gagcaaaatt gtatgcagat
    13201 acgattgcca cagctttgca gacagctcaa gacaagccgg ttaaatcaaa ataacttgta
    13261 ttaaaaaaga gaagagttgg agaaatccag ctcttttaaa atatctccaa aaaataggtc
    13321 tataccattt acaaataaaa aagaaaggtt tataatgtaa ttgacataat aaattgtaga
    13381 atcaatcttt taaggaggtt aacattatgc ctaactatat taaagcggat cagtttttct
    13441 acccacacgg agttcgtcga ggtggttact tggaacttgt ggacggcaag tttggaaaac
    13501 atgtagagca gattcctgaa ggggctgagg tgattgacta tacaggttat agcattgccc
    13561 caggtcttgt ggatactcat attcatggat atgcaggtgt agatgtgatg gacaacaaca
    13621 ttgaaggtac attgcatact atgagtgaag gacttcttag taccggtgtt accagtttct
    13681 tacccacaac tttaacagcc acttatgagc aattgcttgc agtcactgaa aatcttggaa
    13741 accattataa agaagcaaca ggtgctaaga ttcgtgggat ttattatgaa ggtccatatt
    13801 tcacagaaac ttttaagggg gcacaaaatc caacttatat gagagacccg ggtgttgagg
    13861 agtttcattc ttggcaaaaa gcggcaaatg gcttgcttaa taaaattgcc cttgcaccag
    13921 aacgtgatgg ggtggaagac tttgttcgta cagttacggg cgaaggtgtg acggttgctc
    13981 ttggacattc aaacgcgact tttgatgaag ccaaaaaagc agtcgatgct ggagcgagtg
    14041 tttgggtgca tgcctacaat ggaatgcgtg ggttgactca ccgtgaattg ggtatggttg
    14101 gagccatgta ccaattgcca catacctatg cagagttgat ctgtgatggt caccacgtag
    14161 atccaaaggc ttgcgaaatt cttatcaaac aaaaaggaac agaaaacatc gctcttatca
    14221 cagactgtat gacagctggg ggattggaag acggagatta tatgttggga gaattcccag
    14281 ttgtcgttgc aaatggaact gcacgcctca aatcgacagg taacttggca ggttctatcc
    14341 tcaaactcaa agatggtttg aagaatgtgg tcgaatgggg aattgcgaat ccgcatgaag
    14401 cagtcatgat ggccagcttc aacccagcta aatccgttca catcgatgac gtctgtggcc
    14461 aaatccgtga aggctacgac gctgacttca tcgtattaga taaagatttg gaattggtag
    14521 caacctacct agatggcgtg aaacgttatc aagcataaga gagaaggcag aagttagaga
    14581 ctaacttctg cttttttata cagggtactt tactggtaaa taaaaagtta aaaaaatcac
    14641 aaaaaaagct tgaagaaaca aagaaaaatg cttacaattg aactataaat attacaaata
    14701 aaaaaacgga ggagtgcttt atgaaagcct atacttatgt taaaccagga cttgcttctt
    14761 ttgttgatgt agacaaacca gttattcgca agccaacaga cgctattgtg cgtattgtaa
    14821 aaaccactat ttgtggaaca gacctccata ttatcaaagg ggatgttcct acttgccaaa
    14881 gtggtaccat tcttggccac gaagggattg ggattgttga agaagttggg gaaggagttt
    14941 ccaacttcaa aaaaggtgac aaggtcttga tttcttgcgt ctgtgcctgt ggtaaatgct
    15001 actactgtaa aaaaggaatt tatgcccact gtgaagacga agggggctgg attttcggtc
    15061 acttgattga tggtatgcag gctgaatatc tacgtgtccc tcatgcagat aatactcttt
    15121 accatactcc agaagacttg tcagatgaag ctttggttat gctgtcagac attctgccta
    15181 ctggatatga aattggtgtc ttaaaaggga aagtagaacc tggttgcagc gtagccatta
    15241 ttggttcagg tccagttgga ttggctgctc ttttaacagc ccaattctat tcaccagcta
    15301 aattgattat ggtagaccta gacgataacc gcttggaaac tgccctatca ttcggtgcga
    15361 ctcataaggt taattcttca gaccctaaaa aagccattaa agaaatttat gatttgacag
    15421 atggtcgtgg tgtggatgtc gctatcgaag ctgtagggat tcctgaaaca tttgatttct
    15481 gtcaaaagat tatcggtgta gacggaacgg ttgccaactg tggtgtgcat ggtaaaccag
    15541 ttgaattcga tttagataaa ctttggattc gcaacatcaa tgtaacaact ggtttggtat
    15601 ctacaaatac gactccacaa ttgttgaaag cacttgaaag tcataagatt gaaccggaaa
    15661 aattggtaac tcactatttc aaactcagtg aaattgaaaa agcctacgaa gtcttcagta
    15721 aggcagcaga ccaccatgcc attaaggtca ttatcgaaaa cgatatctca gaagcctaag
    15781 tagtaaaaat atttttgtac ataagcaaat agaaattcag tcatccatca gatggctgga
    15841 ttttttatca aaaaattaag aaatgagcat atttctttcc ttgtctggcg gaattggtta
    15901 taatatacgg tacaaaggaa tgaatgaata tgtatcgtgt tatagaaatg tacggagatt
    15961 ttgaaccgtg gtggttctta gaaggttggg aagaagatat tgtagcaagt agaaaatttg
    16021 accagtatta tgatgctctc aaatactaca aaacttgctg gtttagattg gaacaagaat
    16081 cccctcttta taaaagtaga agcgacttga tgaccatttt ttgggacccg gaagaccaac
    16141 gctggtgtga tgaatgtgat gagtatttac aacaatacca ttctttggct cttttgcagg
    16201 atgagcaggt tatcccagac gaaaaactac gctcaggcta tgaaaaacaa accagtcagg
    16261 aaaggaatcg ttcttgccgt atgaaattaa aatagagaaa agtaactttt ttggagttgc
    16321 tttttttatt tttctaacgc tttgcgaata gtataggtga ggaggtaagt atggttcaag
    16381 aaattgcaca agaaatcatt cgttcagctc ggaaaaaagg gacgcaggat atttattttg
    16441 tccctaagtt agacgcctat gagcttcata tgagggtagg agacgagcgc tgtaaaattg
    16501 gtagctatga ttttgaaaag tttgcagccg ttatcagtca ctttaagttt gtggcgggta
    16561 tgaatgtggg agaaaaaaga cgtagtcaac tgggttcctg tgattatgcc tatgaccaga
    16621 agatggcgtc tctacgttta tctactgtag gcgattatcg gggacatgag agtttggtta
    16681 tccgtttgtt gcacgatgag gagcaggact tgcatttttg gtttcaggat attgaagaat
    16741 taggcaagca gtacaggcaa cggggactct atctttttgc tggcccggtt gggagtggta
    16801 agacgacctt gatgcatgaa ttgtccaagt cactctttaa aggacagcaa gttatgtcca
    16861 tcgaagatcc tgtcgaaatc aagcaggacg acatgcttca gttgcagttg aacgaagcaa
    16921 tcggcctaac ctatgaaaat ctaatcaaac tttccttgcg tcatcgacca gatctcttga
    16981 ttatcggaga aattcgtgac agcgagacgg cgcgtgcagt ggtcagagct agtttgacag
    17041 gtgcgacagt cttttcaacc attcacgcca agagtatccg aggtgtttat gagcgtctgc
    17101 tggagttggg tgtgagtgaa gaagaattgg cagttgttct gcaaggagtc tgctaccaga
    17161 gattaatcgg gggaggagga atcgttgact ttgcaaacag agattatcaa gaacaccaag
    17221 cagccaagtg gaatgagcaa attgaccagc ttcttaaaga tggacatatc acaagtcttc
    17281 aggctgagac ggaaaaaatt agctacagct aagcaaaaaa atatcatcac cctatttaac
    17341 aatctctttt ctagcggttt tcatctggtg gagactatct cctttttaga taggagtgct
    17401 ttgttggaca agcagtgtgt gatccagatg cgtgtgggct tgtctcaggg gaaatcattc
    17461 tcagaaatga tggaaagttt gggatgttca agtgctattg tcactcagtt atccctagct
    17521 gaagttcatg gcaatctcca cctgagtttg ggaaagatag aagaatatct ggacaatctg
    17581 gccaaggtca agaaaaaatt gattgaagta gcgacctatc ccttgatttt gctgtttttt
    17641 cttctcttaa tcatgctggg gctacggaat tacctgctcc cacaactgga tagtagcaat
    17701 attgccaccc gaattatcgg taatctgccc caaatttttc taggcatggc agggcttgtt
    17761 tccgtgcttg cccttttagc actaactttt tataaaagaa gttctaagat gaatgtcttt
    17821 tctatcttag cacgccttcc ctttattgga atctttgtgc agacctattt gacagcctat
    17881 tatgcacgtg aatgggggaa tatgatttca cagggaatgg agttgacgca gatttttcaa
    17941 atgatgcagg aacaaggttc ccagctcttt aaagaaatcg gtcaagatct ggctcaaacc
    18001 ctgaaaaatg gccgtgaatt ttctcagacg ataggaacct atcctttctt taggaaggaa
    18061 ttgagtctca tcatagagta tggggaagtt aagtccaagc tgggtagtga gttggaaatc
    18121 tatgctgaaa aaacttggga agcctttttt acccgagtca accgcaccat gaatttggtg
    18181 cagccactgg tttttatctt tgtggcactg attatcgttt tactttatgc ggcaatgctc
    18241 atgcccatgt atcaaaatat ggaggtaaat ttttaaaatg aaaaaaatga tgacattctt
    18301 gaaaaaagct aaggttaaag cttttacatt ggtggagatg ttggtggtct tgctgattat
    18361 cagcgtgctt ttcttgctct ttgtacctaa tctgaccaag caaaaagaag cagtcaatga
    18421 caaaggaaaa gcagctgttg ttaaggtggt ggaaagccag gcagaacttt atagcttgga
    18481 aaagaatgaa gatgctagcc taagcaagtt aaaagacgat gggcgaatca cggaagaaca
    18541 ggttaaagct tataaagaat acaatgataa aaatgtagga gcaaatcgta aagtcaatga
    18601 ttaaggcctt taccatgctg gaaagtctct tggttttggg tcttgtgagt atccttgcct
    18661 tgggcttgtc cggctctgtt cagtccactt ttgcggcagt agaggaacag attttcttta
    18721 tggaatttga agaactctat cgggaaaccc aaaaacgcag tgtagccagt cagcaaaaga
    18781 ctagtctgaa cttagatggg cagacgatta gcaatggcag tcaaaagttg ccagtcccta
    18841 aaggaattca ggtcccatca ggccaaagta ttacatttga ccgtgctggg ggcaattcgt
    18901 ccctggctaa ggttgaattt cagaccagta aaggagcgat tcgctatcaa ttatatctag
    18961 gaaatggaaa aattaaacgc attaaggaaa caaaaaatta gggcagtgat tttactggaa
    19021 gcagtagtcg ctctagctat ctttgccagc attgcgaccc tccttttggg acaaattcaa
    19081 aaaaataggc aagaggaagc aaaaatcttg caaaaggaag aagtcttgag ggtagctaag
    19141 atggccttgc agacggggca aaatcaggta agcatcaacg gagttgagat tcaggtattt
    19201 tctagtgaaa aaggattgga ggtctaccat ggttcagaac agttgttggc aatcaaagag
    19261 ccataaggtc aaggctttta ccttgttaga atccctgctt gccctcattg tcatcagtgg
    19321 gggattactc ctttttcaag ctatgagtca gctcctcatt tcagaagttc gctaccagca
    19381 acaaagcgag caaaaggagt ggctcttgtt tgtggaccaa cttgaggtag aattagaccg
    19441 ttcgcagttc gaaaaagtag aaggcaatcg cctatacatg aagcaagatg gcaaggacat
    19501 cgccatcggt aagtcaaagt cagacgattt tcgtaaaacc gatgctagtg gacgggggta
    19561 tcagcctatg gtttatggcc tcaaatcagc tcagattaca gaggacaatc aactggttca
    19621 ttttcgtttc cagtttcaaa aaggcttaga aagggagttc atctatcgtg tggaaaaaga
    19681 agaaagttaa ggcaggtgtt ctcctctatg cagtcaccat ggcagctatc tttagtcttt
    19741 tgttgcaatt ttacttgaac cgacaagtcg cccactatca agactatgct ttgaataaag
    19801 aaaaattggt tgcttttgcc atggctaaac gaaccaagga taaagccgag caagaaagtg
    19861 gggaacaggt ctttaatcta ggtcaggtaa gctatcaaaa caagaaaaca agcttggtga
    19921 cgactgttcg tacgtctaag agccaatatg agtttctgtt tccttcagtc aaaatcaaag
    19981 aagagaaaag agataaaaag gaagaggtag cgaccgattc aagcgaaaaa gtggagaaga
    20041 aaaaatcaga agagaagcct gaaaagaaag agaattccta gtcaattcaa ctataatgcg
    20101 ttgaatcaag aatagtccac tatagtttct agaaaattgc tggaaatgga tgttaagctc
    20161 caattcattt gtttatatct tatttcagtt tactatactt tgtgctaaat taaagatatg
    20221 aaacatgatt ttaaccacaa agcagaaact ttcgattccc ctaaaaatat cttcctcgca
    20281 aacttggtat gtcaagcagc cgagaaacag attgatcttc tatcagacaa agaaatttta
    20341 gatttcggtg gtgacacggg tctattagcc ttgcccctag cccctagcca agcaggctaa
    20401 gtcagtcact cttgtagaca tttctgagaa aatgttggag caagctcgtt tgaaagtgga
    20461 gcagcaagca atcaagaata tccagttttt ggagcaagat ttaccgaaaa atcccttgga
    20521 gaaagagttt gattgccttg ctgttagtcg ggttcttcat catatgcctg atttggatgc
    20581 ggctctctca ctgtttcatc aacatttgaa gtaagatggg aaactcatca ttgctgattt
    20641 taccaagaca gaagctaatc atcatggatt tgatttagct gaactggaaa acaagctaat
    20701 tgagcatggt ttttcatctg tgcatagtca gattctctat agcgctgaag acttgtttca
    20761 aggaaatcac tcagaattct ttttaatagt agcccaaaaa tcactcgcct agtcagggag
    20821 tgatttttct ataaggatgg aaaaaagaag ggaaatttga taagatagga atatggattt
    20881 tgaaaaaatt gaacaagctt atacctattt actagagaat gtccaagtca tccaaagtga
    20941 tttggcgacc aacttttatg acgccttggt ggagcaaaac agcatctatc tggatggtga
    21001 aactgagcta aaccaggtca aagacaacaa tcaggccctt aagcatttag cactacgcaa
    21061 agaagaatgg ctcaagacct accagtttct cttgatgaag gctgggcaaa cagaaccctt
    21121 gcaggccaat caccagttta caccggatgc tattgcttta cttttggtgt ttattgtgga
    21181 agagctgttt aaagaggagg aaattactat cctcgaaatg ggttctggga tgggaatttt
    21241 gggcgctact ttcttgacct cgcttactaa aaaggtggat tatttgggaa tggaagtgga
    21301 tgatttgctg attgatttgg cagctagcat ggcagatgta attggtttgc aggctggctt
    21361 tgtccaagga gatgccgttc gtccacaaat gctcaaagaa agtgatgtgg tcatcagcga
    21421 cttgcctgtt ggctattatc ctgatgatgc cgttgcgtcg cgccatcaag ttgcttctag
    21481 tcaagaacat acttacgccc atcacttgct catggaacaa ggacttaagt acctcaagtc
    21541 agacggatac gctatttttc tagctccgag tgatttgttg accagtcctc aaagtaattt
    21601 gttgaaagtc tggttgaaag aggaggcaag tctggttgct atgattagtt tacctgaaaa
    21661 tctctttgct aatgctaaac aatctaagac tatttttatc ctacagaaga aaagtgaaat
    21721 agcagtagag ccttttgttt atccacttgc tagcttgcaa gatgcaagtg ttttaatgaa
    21781 atttaaagaa aattttcaaa aatggactca aggtactgaa atataaaata gattttgtta
    21841 taatagttga aaacgcttaa aaaggggtat catgttatga caaaaacaat tgcaatcaat
    21901 gcaggaagtt caagtttgaa atggcaatta tacttaatgc cagaagaaaa agtattggcg
    21961 aaaggtttga ttgaacgtat cggtttgaaa gattcaattt caactgtaaa atttgacggc
    22021 cgttctgaac aacaaatttt ggatattgaa aatcatacac aagctgttaa aattttattg
    22081 gatgacttga ttcgtttcga tattatcaag gcttatgacg agattacagg tgttggacat
    22141 cgtgttgttg ctggtggaga atatttcaaa gaatcaacag ttgttgaggg agatgtttta
    22201 gaaaaagttg aagagttgag tttgttggct cctctacaca acccggcaaa tgcagcaggt
    22261 gttcgtgcct tcaaggaatt gttgccagac attaccagtg tagttgtttt tgatacttcc
    22321 ttccacacaa gtatgccaga gaaagcttat cgctaccctc taccaacaaa atattacaca
    22381 gaaaacaagg ttcgtaaata cggtgctcat ggtacaagtc accagtttgt agcaggagaa
    22441 gctgcaaaac tcttgggacg tccattagaa gacttgaagt taattacctg tcatattggt
    22501 aacggaggct caattacagc tgtgaaagcc ggcaaatctg tagacacttc tatggggttc
    22561 actcctcttg gtggtattat gatgggaacg cgtacagggg atattgatcc agctatcatt
    22621 ccttatttaa tgcaatatac agaggatttt aacacaccag aagatatcag tcgtgttctt
    22681 aaccgtgaat caggtctttt gggagtttct gctaattcta gcgatatgcg cgatatagaa
    22741 gcagctgtag cagaagggaa tcacgaggct agcttggctt atgaaatgta tgttgaccgt
    22801 atccaaaaac atatcggtca gtaccttgca gtgctaaatg gagcagatgc cattgttttc
    22861 acagcaggtg tcggtgaaaa tgcagagagt ttccgtcgtg atgtaatctc agggatttcg
    22921 tggtttggtt gtgatgttga tgatgaaaag aatgtctttg gcgttacagg agacatctca
    22981 acagaggcag ctaaaatccg tgtcttggtt attccaacag atgaagaatt agtcattgcc
    23041 cgtgacgttg aacgcttgaa aaaataagtg aaactaaaaa aatattcaat acaaggagtt
    23101 gggaaagtta tttttccagc ttctttttct gatgaaattg tccaaaacct tgctatgatt
    23161 ggcttttttg aaaaatatgg tataatagta gtaatttaat agatggagtt gagttttgaa
    23221 gaaaaacttt cgtgtaaaaa gagagaaaga ttttaaggcg attttcaagg aggggacaag
    23281 ttttgctaat cgcaaatttg tggtctacca attagaaaac cagaaaaacc attttcgagt
    23341 aggtctatca gttagcaaaa aactggggaa tgccgtcact agaaatcaaa ttaagcgacg
    23401 gattcggcat attatccaga atgcaaaagg gagtctggta gaagatgtcg actttgttgt
    23461 cattgctcga aaaggagtcg aaaccttggg atacgcagag atggagaaaa atctactcca
    23521 tgtattaaaa ttatcaaaga tttaccggga aggaaatggg agtgaaaaag aaactaaagt
    23581 tgactagttt gctaggactg tctctgttaa tcatgacagc ctgtgcgact aatggggtaa
    23641 ctagcgatat tacagccgaa tcggctgatt tttggagtaa attggtttac ttctttgcgg
    23701 aaatcattcg ctttttatcg tttgatatta gtatcggagt ggggattatt ctctttacgg
    23761 tcttgattcg tacagtcctc ttgccagtct ttcaggtgca aatggtggct tctaggaaaa
    23821 tgcaggaagc tcagccacgc attaaggcgc ttcgagaaca atatccaggt cgagatatgg
    23881 aaagcagaac caaactagag caggaaatgc gtaaagtatt taaagaaatg ggtgtcagac
    23941 agtcagactc tctttggccg attttgattc agatgccggt tattttggcc ctgttccaag
    24001 ccctatcaag agttgacttt ttaaagacag gtcatttctt atggattaac cttggtagtg
    24061 tggatacaac ccttgttctt ccgattttag cagcagtatt caccttttta agtacttggt
    24121 tgtccaacaa agctttgtct gagcgaaatg gcgctacgac tgcgatgatg tatgggattc
    24181 cagtcttgat ttttatcttt gcagtttatg cgccaggtgg agtcgcccta tactggacag
    24241 tgtctaatgc ttatcaagtc ttgcaaacct atttcttgaa taatccattc aagattatcg
    24301 cagagcgcga ggccgtagta caggcacaaa aagatttgga aaatagaaaa agaaaagcca
    24361 agaaaaaggc tcagaaaacg aaataaataa ggaggaatct ggtaatggta gtatttacag
    24421 gttcaactgt tgaagaagca atccagaaag gattgaaaga attagatatt ccaagaatga
    24481 aggctcatat caaagtcatt tctagggaga aaaaaggctt tcttggtcta tttggtaaaa
    24541 aaccagccca agtggatatt gaagcgatta gtgaaacgac tgttgtcaaa gcaaatcaac
    24601 aggtagtaaa aggcgttccg aaaaaaatca atgatttgaa cgagcctgtg aagacggtta
    24661 gtgaagaaac cgttgacctt ggtcatgtgg ttgatgctat taaaaaaata gaggaagaag
    24721 gtcaaggtat ttctgatgaa gtcaaggctg aaatcttaaa acatgaaaga catgccagca
    24781 ctatcttaga agaaactggt cacattgaga ttttaaatga acttcaaatc gaggaagcga
    24841 tgagggaaga agcaggcgct gatgaccttg aaactgagca agatcaaact gaaaatcaag
    24901 acttgaaaga gatgggcttg aaggtcgagc aaagttatga tattgcccag gtggctacgg
    24961 atgtgactgc ctatgttcaa gcgattgtgg atgacatgga tgttgaagct acactttcaa
    25021 atgattataa ccgtcgtagc atcaatctac aaattgacac caacgaacca ggtcgtatta
    25081 tcggctacca tggtaaagtc ttgaaggcct tgcaactgtt ggctcaaaat tatctttaca
    25141 accgctattc cagaaccttc tacgttacaa tcaatgtcaa tgattatgtc gaacaccgtg
    25201 cagaagtctt gcagacctat gcgcaaaaat tggcgactcg tgttttggaa gaagggcgca
    25261 gtcataaaac agatccaatg tcaaatagcg aacgcaagat tatccatcgt attatttcac
    25321 gtatggatgg cgtgactagt tactctgaag gtgatgagcc aaatcgctat gttgttgtag
    25381 atacagaata agtaaaatca ggtttatcct gattttttgc tagttagagg aggttaaact
    25441 gatgttgaat aagataagag actatttaga ctttgctggt ttgcagtacc gtaatcctga
    25501 taaagcggga gcagagcgag agaagatgct ggcattccgc cacaaaggac aagaggcccg
    25561 aaaggctttt acagaactgg ccaaagcctt tcaagcaagc catccagaat ggcaactcca
    25621 acagactagc cagtggatga atcaggccca gcgtttgaga ccacattttt gggtttatct
    25681 acagagagac ggacaagtga cagaacctat gatggcctta cgtttgtatg ggacatctac
    25741 tgactttgga atttctttgg aagtcagttt catcgaacgt aagaaggatg agcaaacact
    25801 gggcaagcag gccaaagttt tagacattcc aaccgttaaa gggatttatt atctaaccta
    25861 ctctaatggt caaagtcaac ggtgggaggc gaatgaagaa aagcgtcgta ctttacgcga
    25921 gaaggtgaga agtcaagaag ttcgaaaagt tttagtgaag gtagatgttc ctatgacaga
    25981 aaattcgtct gaagaagaaa tcgtagaagg cttattgaag tcttattcta aaattcttcc
    26041 ctattatcta gctacgagaa aataagataa tttgtaaaac atcataaatc atacagtcca
    26101 agagtgaaca gtccgctgtg taattcttgg tctttttgtt tgcgctttcg cattatataa
    26161 taaacttaca aaaacaattc aaaaggagaa caattatgga agtcgtttca agtgttctaa
    26221 attggttttc tagcaatatt ttgcagaatc ccgcattttt cgtaggttta ttggtgttga
    26281 taggatatgc acttttgaaa aaacctgccc atgacgtttt ttcagggttt gttaaagcaa
    26341 cagtagggta tatgttgctt aacgtgggtg ctggtggttt ggttacaacc tttcgtccaa
    26401 tcttagcagc tcttaactac aaattccaaa ttggtgcagc ggttatcgac ccttactttg
    26461 gacttgctgc agcaaacaac aaaattgcag cagagtttcc agattttgtt ggaactgcaa
    26521 ctacagctct attgattggt tttggaataa atatcttgct cgtagctctt cgaaagatta
    26581 cgaaggtaag aaccctcttt attactggtc acatcatggt acaacaagct gcaacagtat
    26641 ctcttatggt tctattctta gtaccacaat tgcgcaatgc ttacggtaca gcagcgattg
    26701 gtatcatctg tggactttac tgggcagtta gttcaaatat gactgttgag gcaactcaac
    26761 gcttgactgg tggtggcgga tttgcgattg gtcaccaaca gcaatttgca atctggtttg
    26821 tagataaagt agcaggacgc tttggtaaga aagaagaaag tttagacaat cttaaattac
    26881 ctaagttcct ctcaatcttc cacgatacag ttgttgcatc tgctaccttg atgctcgtat
    26941 tcttcggagc cattctttta atcttgggtc cagacattat gtctaataaa gaagtcatca
    27001 cttcaggaac tctattcaat cctgctaaac aagatttctt tatgtacatt atccaaacag
    27061 cctttacctt ctcagtttac ttgttcgttt tgatgcaagg tgtccgaatg ttcgtatctg
    27121 agttgacaaa cgccttccaa ggtatttcaa acaaattgtt gccaggttca ttcccagcgg
    27181 ttgacgttgc agcttcttat ggatttggtt ctccaaatgc tgtcttgtca ggatttacct
    27241 ttggtttgat tggtcaattg attacaattg tcttgctcat cgtctttaaa aatccgattc
    27301 ttattattac aggatttgta ccagtgttct ttgacaatgc agccattgcg gtctacgctg
    27361 ataaacgcgg cggatggaaa gcggctgtta tcctttcctt tatatcaggt gtccttcaag
    27421 ttgctctagg agctctttgt gtggcccttc tcgatttggc atcttatggt ggctaccatg
    27481 gaaatatcga ctttgaattc ccatggcttg gatttggata tatcttcaaa taccttggta
    27541 ttgttggtta tgtacttgtg tgtctcttct tgcttgttat tcctcaactt caatttgcca
    27601 aagcaaaaga taaagagaaa tattacaacg gtgaagttca agaagaagct tagtatctag
    27661 aaaaggagaa ataaaatggt taaagtatta gcagcgtgcg gaaatggaat gggttcatca
    27721 atggttatca agatgaaggt tgaaaatgct ctccgtaagc ttaatcaaac agattttaca
    27781 gtcaattcat gcagtgtcgg tgaagctaaa ggtttagcag taggatatga catcgtaatc
    27841 gcttctcttc atttgattca agaattggaa gggcgaacta atgggaagtt aattggtctt
    27901 gataacttga tggatgataa agaaatcacc gaaaaactca gtcaagcact acagtaaaag
    27961 gttggagggg gctggacaga aactgagagt tatcgtttct gtccttctcc ctctttaaat
    28021 aaaggaggca gatatgaatt taaaacaagc tttaattgac aatgactcga tccgactagg
    28081 tttagaggct aacaattgga aagaagcagt caaggtagca gtagatcccc taattgaaag
    28141 tggggcaatt ttgccagagt attacgatgc tatcattgaa tcgactgaag agtatgggcc
    28201 ttactatatc ttgatgccag gtatggctat gccccacgct agacctgaag ctggtgtgca
    28261 aagtgatgcc ttttcattga ttaccttaca aaatcctgtt gtattttcag atgggaaaga
    28321 ggtatctgtt ttgttggcac tagcagcaac aagttcaaaa attcacacaa gtgtagccat
    28381 tccacaaatt attgccctgt ttgaattaga agattctatt gcacgtttac aggcttgcca
    28441 gactaaagaa gatgtcttgg ctatgattga agaatctaag gatagccctt atctcgaagg
    28501 attggatttg gaaagttaga aagaggaata aagaaatgac aaaaagaata cctaatttac
    28561 aagttgcatt agaccattca gacttgcaag gagcgattaa agcagctgtt tctgttggtc
    28621 aggaagtaga tattatcgaa gctggaactg tttgcttgct tcaagttgga agtgaactgg
    28681 ctgaagtctt gcgtagcctt ttcccagata agattattgt ggcagacaca aaatgtgctg
    28741 atgctggtgg aacagttgct aaaaataatg cggttcgtgg agcagactgg atgacttgta
    28801 tctgttgtgc aaccatccct actatggaag cagctctaaa ggctatcaag actgaacgag
    28861 gagaacgagg cgaaatccag atcgagcttt atggcgattg gacttttgaa caagctcagc
    28921 tttggctaga tgcaggtatc tcacaagcta tttatcacca atctcgtgat gctcttcttg
    28981 ctggtgaaac ttggggtgaa aaagacctta ataaggttaa aaaactcatt gacatgggct
    29041 tccgtgtatc tgtaacaggt ggtctagatg tagatactct caaactcttt gaaggtgttg
    29101 atgtctttac ctttatcgca ggtcgtggaa ttacagaggc tgcggatcca gcaggagcag
    29161 cgcgtgcctt caaggatgaa atcaaacgaa tttgggggta aatcatggta cgtccaattg
    29221 gaatttatga aaaggcaacc ccaacacact ttacttggct agaacgttta aattttgcca
    29281 aggagttagg ctttgatttt gtcgagatgt ctattgacga acgtgacgag cgtttagcaa
    29341 gacttgactg gagtaaggaa gaacgcttgg aagttgtcaa agcaatctat gaaactggtg
    29401 ttcgtattcc ttctatctgt ttttcaggcc atcgtcgcta cccattgggt tcaaaagatc
    29461 cagttctaga ggaaaaatct ctagaactca tgaaaaaatg tatcgaatta gctcaagact
    29521 tgggagttcg tacgattcaa ttagctggtt acgatgttta ctatgaggaa aagtcacccc
    29581 agacacgcca acgttttatc aaaaatttga gaaaagcctg tgactgggct gaagaagctc
    29641 aggtggtact tgctattgaa attatggatg atcctttcat cagtagcatc gaaaaatatt
    29701 tggctataga aaaagagatt gactctccct tcctctttgt atatccagat attggtaatg
    29761 tgtctgcatg gcataatgat atctatagtg agttttatct tggtcatcat gccatcgcag
    29821 ctctccatct caaggatact tatgcagtga cagaaagttc aaagggccag ttccgagatg
    29881 tacctttcgg gcaaggttgt gtcaaatggg aagaagcttt cgatatttta aaggaaacca
    29941 attataatgg acctttccta atcgaaatgt ggtctgaaaa ttgtgaaaca gtagaagaaa
    30001 cacgcgcagc cgttcaagag gcgcaagctt ttctctatcc actcattaag aaagcaggtt
    30061 tgatgtaaga tgaatcaagt aatcaatgct atgcgtaaac gagtctgtga tgccaatcaa
    30121 tcattgccaa aacatggact tgtcaaattt acctggggga atgtatctga agttaatcgc
    30181 gaactcggtg tcattgttat caaaccatca ggcgtggatt atgacgaatt gacacctgaa
    30241 aacatggtag tgactgatct agatggtaag atcctagaag gggatttaag accatcttcc
    30301 gacctcccaa ctcatgtgca attatataag gcttggtcag aaattggtag tgtggttcac
    30361 acccattcga cagaagctgt tggttgggct caggcaggtc gtgatattcc tttctacgga
    30421 acaacccatg cagattattt ctacggttca atcccttgcg cccgtagttt gaccaaggac
    30481 gaagtagaag tggcctatga aaaagatact ggcctggtta tcgtagaaga gtttgaacat
    30541 cgcggactta acccggttga agtaccagga attgttgtac gcaatcacgg tccattcacc
    30601 tggggcaaaa atccagagaa tgctgtttat cactctgtcg tactagagga agtatcaaag
    30661 atgaatcgct ttacagaaca aatcaatcca agagttggac ctgctcccca gtacatacta
    30721 gaaaaacact accaacgtaa acatggacca aatgcttatt atggtcaaaa gtaagaacga
    30781 tgaaggagga gaaaaagata aatttagctc ctctttttac atttgatttt tattgagagt
    30841 aaagttggaa ttgaagtaat tttaaaagat tttttagaaa tagcgcttga tatatatatg
    30901 gtaaaataaa aagaattgct gtgatatcaa tagatttggg ggatttttta atatggtact
    30961 ggataaggca agttgtgatt tgcttcaata tttgatggat caagaaacgt ccaaaacgat
    31021 tatggcgatt tcgaaagatt tgaaagagtc aagaaggaaa atttattatc acattgacaa
    31081 aatcaatgct gctctgggtg acgaggcgct tcacatcatt agtattccac gaattggtat
    31141 tcacttaacg gaagagcaga gagatgcttg ttgtaaacta ttatcggaag tagattcgta
    31201 cgattatatc atgagtgcgc atgaacgtat gatgataatg ttactatgga taggtatttc
    31261 taaagaacgt attacgattg aaaaattgat agagttaaca gaggtatcta ggaatactgt
    31321 tctcaatgat ttgaatagta ttcgttatca actaactttg gaacaatatc aggtgatctt
    31381 gcaagtgagc aagtcacagg gataccacct tcatgcccac cctcttaata aaattcagta
    31441 tcttcaatcg cttctatatc atatttttat ggaagaaaat gccacttttg tatctatttt
    31501 agaagataag atgaaagaga ggttagatga tgagtgtttg ctttctgttg aaatgaacca
    31561 attttttaag gaacaggttc ctttagttga acaagattta gggaagaaaa taaaccatca
    31621 tgaaataact tttatgttgc aggttctacc ttatttgctg ttaagctgtc ataatgttga
    31681 acagtatcaa gaaagacatc aggatataga gaaagaattt tctttgataa gaaaaagaat
    31741 agagtatcag gtgtctaaga aattaggaga acggttgttt caaaagtttg aaatttcttt
    31801 gtcaggactt gaagtttctc ttgtagctgt tctcctcctc tcctatcgta aagatttgga
    31861 tattcatgca gaaagtgatg attttcggca attaaaactt gctttagaag aatttatctg
    31921 gtattttgaa tcacaaatcc gaatggagat tgagaacaag gatgatttgt tacgaaattt
    31981 gatgatccac tgtaaagcct tgttatttag aaagacttac ggtatttttt ctaaaaatcc
    32041 tctaacaaaa caaattcgat ccaagtatgg agaattattt ttagtcacta gaaaatctgc
    32101 ggaaatttta gaaggagcat ggtttattcg gctaacagac gatgatattg cctatttgac
    32161 gattcatatt ggaggatttt taaaatatac accatcgtct caaaaaaata tgaaaaaagt
    32221 ttatctcgtt tgtgatgaag gtgttgcggt ttcgagactt ttgctgaaac aatgcaaact
    32281 ttattttcca aatgagcaaa ttgacactgt atttacaaca gaacaattta agagtgtgga
    32341 agatattgca caagttgatg tagtgattac tactaatgat gatttggata gcagatttcc
    32401 gattttaagg gttaatccta tccttgaagc agaagatatt ttgaaaatgc tagactatct
    32461 taaacacaat atatttcgta ataagagcaa aagtttcagt gaaaatcttt ctagtcttat
    32521 ttcgtcttat attgtagata gcaagttggc tagtaagttc caagaagagg ttcaaacact
    32581 tataaatcaa gaaatagtag ttcaagcttt tttggaagat atttgaagga cagtccaatg
    32641 atgaacacaa acctgtgttt ttcttggtct tttttagtgt tttgaagggt ggtatactaa
    32701 tctcaaagat aacaattata tccaaaggag gcaacatatg ccaaacgtca aagaaattac
    32761 aagagagtca tggattttag ccactttccc agagtgggga acatggttga acgaagaaat
    32821 cgaagaagaa gtcgtacctg aaggcaactt tgccatgtgg tggctaggca actgtggtac
    32881 ttggattaag acaccagctg gtgctaacgt tgtcatggac ctttggtcaa accgtggaaa
    32941 atcaaccaaa aaagtgaaag atatggttcg tgggcaccaa atggcaaata tggcaggtgt
    33001 tcgtaagttg caaccaaact tgcgtgttca gccaatggtt atcgatccat ttgctatcaa
    33061 cgaactagac tattacttag tttcacactt ccacagtgat catatcgacc catacacagc
    33121 tgcagcaatt ctcaacaatc ctaagttaga gcatgttaag tttatcggtc cttaccactg
    33181 tggacgaatc tgggaaggat ggggtgttcc aaaagaacgt atcatcgttg ttaaaccagg
    33241 tgacactatc gaattaaaag atatgaagat tcatgcagta gaatcatttg accgtacttg
    33301 cttggtaact ctcccagtga acggtgctga tgagacaggc ggtgaacttg ctggcttggc
    33361 tgttacagat gaagaaatgg ctcaaaaggc tgttaactat atctttgaaa caccaggtgg
    33421 aaccatctat catggtgcag attctcactt ctcaaactat tttgcaaaac atggtaaaga
    33481 ctttaaaatt gatgttgctt tgaataacta tggtgaaaat ccggtaggta tccaagacaa
    33541 aatgacatct atcgaccttc ttcgtatggc agaaaatctg cgtaccaaag tcattatccc
    33601 agttcactat gatatctggt ctaacttcat ggcttctact aatgagattc tagaactttg
    33661 gaaaatgcga aaagatcgct tgcaatacga tttccatcca tttatctggg aagttggcgg
    33721 taagtacact tatcctcaag atcaacactt agtagaatac catcatccac gtggttttga
    33781 tgattgtttt gaacaagact ctaacattca atttaaagct ttgctataat ataaaaatat
    33841 tctttggagg ttatccgtat gttgcatgat acggataatt ttcatataat agtaaaatag
    33901 aatgtgtgat tcaataatca cctcaaatag aaaggaaatt ctatgtcaaa tctatctgtt
    33961 aatgcaattc gttttctagg tattgacgcc attaataaag ccaactcagg tcatccaggt
    34021 gtggttatgg gagcggctcc gatggcttac agcctcttta caaaacaact tcatatcaat
    34081 ccagctcaac caaactggat taaccgcgac cgctttattc tttcagcagg tcatggttca
    34141 atgctccttt atgctcttct tcacctttct ggttttgaag atgtcagcat ggatgagatt
    34201 aagagtttcc gtcaatgggg ttcaaaaaca ccaggtcacc cagaatttgg tcatacggca
    34261 gggattgatg ctacgacagg tcctctaggg caagggattt caactgctac tggttttgcc
    34321 caagcagaac gtttcttggc agccaaatat aaccgtgaag gctacaatat ctttgaccac
    34381 tatacttacg ttatctgtgg agacggagac ttgatggaag gtgtctcaag cgaggcagct
    34441 tcatacgcag gtttgcaaaa acttgataag ttggttgttc tttatgattc aaatgatatc
    34501 aacttggatg gtgagacaaa ggattccttt acagaaagtg ttcgtgaccg ttacaatgcc
    34561 tacggttggc atactgcctt ggttgaaaat ggaacagact tggaagccat ccatgctgct
    34621 atcgaaacag caaaagcttc aggcaagcca tctttgattg aagtgaagac ggttattgga
    34681 tacggttctc caaacaaaca aggaactaat gctgtacacg gcgcccctct tggagcagat
    34741 gaaactgcat caactcgtca agccctcggt tgggactacg aaccatttga aattccagaa
    34801 caagtatatg ctgatttcaa agaacatgtt gcagaccgtg gcgcatcagc ttatcaagct
    34861 tggactaaat tagttgcaga ttataaagaa gctcatccag aactggctgc agaagtagaa
    34921 gccatcatcg acggacgtga tccagtcgaa gtgactccag cagacttccc agctttagaa
    34981 aatggttttt ctcaagcaac tcgtaattca agtcaagatg ccttgaatgt tgtggcagct
    35041 aaattaccaa ccttcctagg tggatcagct gaccttgctc actcaaacat gacttatatc
    35101 aagacggatg gacttcaaga cgataccaat cgcttgaatc gtaacattca gtttggtgtt
    35161 cgtgaatttg caatgggaac aatcttgaac gggatggccc ttcatggtgg acttcgtgta
    35221 tacggtggaa ctttcttcgt cttctctgac tatgtgaagg cagctgtccg tttgtcagcc
    35281 ttacaaggac ttcctgtgac ttatgtcttt acccatgatt caatcgcagt tggggaagat
    35341 ggtccgactc acgaaccagt tgagcattta gcaggtcttc gtgctatgcc aaatctaaat
    35401 gttttccgtc cagcagatgc gcgtgaaacg caagcagctt ggtaccttgc agtgacaagt
    35461 gagaaaacac caactgccct tgtcttgaca cgtcaaaact tgactgttga agatggaaca
    35521 gacttcgaca aggttgctaa aggtgcttat gttgtatatg aaaatgcagc cgactttgat
    35581 accatcttga ttgcgacagg ttcagaggtt aatcttgctg tctcagctgc taaagaattg
    35641 gctagtcaag gcgaaaaaat ccgcgtagtc agcatgccat ctacagatgt ctttgataaa
    35701 caagatgcag cttacaagga agaaattctt ccaaatgcag tccgccgtcg tgttgcagtc
    35761 gaaatgggtg caagtcaaaa ctggtacaaa tatgttggtc tcgatggtgc cgttctaggt
    35821 attgatacct tcggagcctc tgccccagca ccaaaagtat tggcagaata tggctttact
    35881 gtcgaaaatc ttgtaaaagt tgttcgaaat ttgaaataat cctaaaaatc agggcgtaag
    35941 ctctggtttt tcttaccaga aaagtaaggt acaatcttgt aaaagtagct gaaatttgat
    36001 atagtagtcc tatgtaaaag acaaaggaga aaacaatgaa tccaaatatt acttttttaa
    36061 tcatgcttgt aggtatgatg gccttgatgt tctttatgca acgttctcaa aagaaacaag
    36121 ctcaaaagcg tatggaaagc ttaaataaac tacaaaaagg ctatgaagtg attacaatcg
    36181 gtggacttta tggaacagtc gatgaagtag atacggagaa gggaacaata gttcttgacg
    36241 tagatggagt ttacttgact tttgaactag ctgctatcaa gacagtatta ccgctgaaag
    36301 aaacagcttc actagaaggc gcaattgaaa aataagacgg gatcacgaac tcccgttttc
    36361 tataaaagaa aggaaatggg atgaaaaaat tagtctttgt ctgtctggga aatatttgcc
    36421 gtagccctat ggccgagttt gttatgaaat caatgacaga taactacgaa atccaaagtc
    36481 gagcaacttc ctcttgggaa catggcaatc cgattcataa ggggactcag ggaatttttc
    36541 aagagtatga gattccttat gacaagaaca agacatcgct tcagattagt aaggaagatt
    36601 ttgaagcctt tgattatatt atcggaatgg acgcttcaaa tatttctgac ttacgtcaga
    36661 tgtgtccagt agactgtcaa gataagattt actcattttc atctgaaagt gttccagacc
    36721 cttggtatac aggagatttt gaagaaacct atcgacgtgt tcaagagggc tgtcaagctt
    36781 ggttagaacg tttagaaaag gagagttaag gtggaaaatc ttacgaattt ttacgaaaag
    36841 tatcgtgtct atctgactcg tccacgttta gagcttttgg cagtagttac cattgttttc
    36901 tgtgctgtac tcgtcttttt tctaaatatt ccaggaaaag gtgtcttaaa actcgataat
    36961 ggaacgattg tttatgatgg cagtcttgtc cgtggtaaaa tgaatggcca aggtaccatt
    37021 accttccaaa atggagacca atatacaggt ggcttcaaca atggagcctt caacggaaaa
    37081 ggtacctttc aatctaaaga aggctggacc tacgaaggtg attttgtaaa tggtcaggct
    37141 gaaggaaaag ggaaactaac aacagaacaa gaagtcgttt atgaaggaac ttttaaacaa
    37201 ggcgtttttc aacaaaaata aagcctccta tcaaaggagg tattattaga atcacaaggt
    37261 aagcgcttac ctgtgaatcc ctttctttcc aaatccctct tccaagcaag tttgtgaaat
    37321 aaaaaatatt tgaaataaat ttcacaaact tcaaagataa aacttgataa gaaaagaaaa
    37381 tgagaaaagt ttcacaagag tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca
    37441 aagttgaaat aatgcgttat aataaacttg tgaaaaaatt aacaaaggat atcgttcctt
    37501 gaaagctatg gaggaaaata tggctgataa aaaaactgtg acaccagagg aaaagaaact
    37561 cgttgctgaa aaacacgtag atgagttggt tcaaaaagct ctagttgccc ttgaagaaat
    37621 gcgtaaattg gatcaagaac aagttgacta catcgttgcc aaagcatcag tagcagcttt
    37681 ggatgcccac ggagaattgg ctttacatgc ctttgaagaa acaggacgtg gtgtatttga
    37741 agacaaagca actaagaact tgtttgcttg tgaacacgta gtaaacaaca tgcgccacac
    37801 taagacagtt ggcgttatcg aagaagacga tgtaacagga ttgactctta ttgctgaacc
    37861 agttggtgtt gtttgtggta ttactccaac aacaaaccca acatcaacag caatcttcaa
    37921 atcattgatt tcattgaaga cacgtaaccc aatcgtcttt gccttccatc catcagcaca
    37981 agaatcatct gctcatgcag ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc
    38041 tgaaaactgt gtacagtgga tcactcaacc atctatggaa gcaactagtg cccttatgaa
    38101 ccacgaaggt attgcaacaa tccttgcaac aggtggtaat gccatggtta aagccgcata
    38161 ctcatgtggt aaaccagctc ttggggtagg tgccggaaac gttccagctt atgttgaaaa
    38221 atcagcaaac attcgtcaag cagcacacga tatcgtcatg tctaaatcat ttgataacgg
    38281 tatggtctgt gcatctgaac aagcagttat cattgataaa gaaatttacg atgaatttgt
    38341 agcagagttc aaatcttacc acacttactt tgtaaacaaa aaagaaaaag ctcttcttga
    38401 agagttctgc ttcggcgtca aagcaaacag caaaaactgt gctggtgcaa aattgaacgc
    38461 tgacatcgtt ggtaaaccag caacttggat tgcagaacaa gcaggattta cagttccaga
    38521 aggaacaaac attcttgctg cagaatgtaa agaagttggc gaaaatgagc cattgactcg
    38581 tgaaaaattg tcaccagtta ttgcagtttt gaaatctgaa agccgtgaag atggtattac
    38641 taaggctcgt caaatggttg aatttaacgg tcttggacac tcagcagcta tccacacagc
    38701 tgacgaagaa ttgactaaag aatttggtaa agctgttaaa gctattcgtg ttatctgtaa
    38761 ctcaccttct acttttggtg gtatcgggga cgtttacaat gccttcttgc catcattgac
    38821 acttggatgt ggttcttacg gacgcaactc agttggggat aacgttagtg ccattaacct
    38881 cttgaatatc aaaaaagtcg gaagacggag aaataacatg caatggatga aacttccttc
    38941 aaaaacatac tttgaacgtg attcaattca ataccttcaa aaatgtcgtg acgttgaacg
    39001 tgtcatgatc gttactgacc atgccatggt agagcttggt ttccttgatc gtatcatcga
    39061 acaactggac cttcgtcgca ataaggttgt ttaccaaatc tttgcggatg tagaaccgga
    39121 tccagatatc acaactgtaa accgtggtac tgagattatg cgtgccttca aaccagatac
    39181 catcatcgca ctcggtggtg ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta
    39241 cgagcaacca gaagtggact tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg
    39301 tgccttcaag ttcccattgc ttggtaagaa gactaaattc atcgcgattc caactacatc
    39361 tggtacagga tctgaagtaa caccatttgc cgttatctct gataaagcaa acaaccgtaa
    39421 atacccaatc gctgactact cattgacacc aactgtggca atcgtagatc ctgctttggt
    39481 attgacagtt ccaggatttg ttgctgctga tactggtatg gacgtattga ctcacgcgac
    39541 agaagcatac gtatcacaaa tggctagtga ctacactgat ggtttagcac ttcaagccat
    39601 taaattggtc tttgaaaatc tcgaaagctc agttaagaat gcagacttcc actcacgtga
    39661 gaaaatgcat aacgcttcaa caatcgctgg tatggccttt gccaatgcct tcctaggtat
    39721 ttctcactca atggcccata agattggtgc gcaattccac acaatccacg gtcgtacaaa
    39781 tgctatcttg cttccatacg ttatccgtta caacggtaca cgtccagcta agacagcaac
    39841 atggcctaag tacaactact accgtgcaga tgaaaaatac caagatatcg cacgcatgct
    39901 tggacttcca gcttctactc cagaagaagg ggttgaatct tacgcaaaag ctgtctacga
    39961 actcggtgaa cgtattggga tccaaatgaa ttttagagac caaggaattg acgaaaaaga
    40021 atggaaagaa cattctcgtg aattagcctt cctggcttat gaagaccaat gttcaccagc
    40081 taacccacgt cttccaatgg tagaccatat gcaagaaatc atcgaagatg catactatgg
    40141 ctacaaagaa agaccaggac gccgtaaata attgtttatc agtctagaag caagacaaaa
    40201 actcaatttg agggaaagat ccagtacttt ttctatgata aaaggcatcc tatcaaggtt
    40261 tttgaacacc tgataggatg cctttttatg atattgaggc ctttttgccc tttttgaaaa
    40321 actagaatag aaacaaaata tataatagat tgaaactgga atagtacact tctgcttcta
    40381 aaacattgtt agaattcgat ttgactgtcc tgatcgattt gtcctgttct tatttcattt
    40441 taatatataa aaaatat
//
LOCUS       DAVBOM010000014        38411 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBOM010000014 DAVBOM010000000
VERSION     DAVBOM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.014"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ878_000792"
     CDS             complement(56..1066)
                     /locus_tag="VQ878_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET3095155.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNALESATIVKLT
                     RTLAIIPITIFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ878_000793"
     CDS             1215..2384
                     /locus_tag="VQ878_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3095156.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQTIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ878_000794"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ878_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET3095157.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ878_000795"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ878_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET3095158.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDIGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ878_000796"
     CDS             4146..4379
                     /locus_tag="VQ878_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3095159.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4425..4715
                     /locus_tag="VQ878_000797"
                     /pseudo
     CDS             4425..4715
                     /locus_tag="VQ878_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4918..5148
                     /gene="blpU"
                     /locus_tag="VQ878_000798"
     CDS             4918..5148
                     /gene="blpU"
                     /locus_tag="VQ878_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET3095160.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5863..8016
                     /locus_tag="VQ878_000799"
     CDS             5863..8016
                     /locus_tag="VQ878_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET3095161.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8029..9378
                     /locus_tag="VQ878_000800"
     CDS             8029..9378
                     /locus_tag="VQ878_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET3095162.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9548..10255
                     /locus_tag="VQ878_000801"
     CDS             9548..10255
                     /locus_tag="VQ878_000801"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET3095163.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10457..14182
                     /locus_tag="VQ878_000802"
     CDS             10457..14182
                     /locus_tag="VQ878_000802"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET3095164.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDVTELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMNWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNSYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14275..15717
                     /locus_tag="VQ878_000803"
     CDS             14275..15717
                     /locus_tag="VQ878_000803"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET3095165.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPSNLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15754..16776
                     /locus_tag="VQ878_000804"
     CDS             15754..16776
                     /locus_tag="VQ878_000804"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET3095166.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTESAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16773..17318
                     /gene="purN"
                     /locus_tag="VQ878_000805"
     CDS             16773..17318
                     /gene="purN"
                     /locus_tag="VQ878_000805"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET3095167.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYLEVVKALFTD"
     gene            17402..17911
                     /locus_tag="VQ878_000806"
     CDS             17402..17911
                     /locus_tag="VQ878_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3095168.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17936..19483
                     /gene="purH"
                     /locus_tag="VQ878_000807"
     CDS             17936..19483
                     /gene="purH"
                     /locus_tag="VQ878_000807"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET3095169.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19605..20867
                     /gene="purD"
                     /locus_tag="VQ878_000808"
     CDS             19605..20867
                     /gene="purD"
                     /locus_tag="VQ878_000808"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET3095170.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21270..21758
                     /gene="purE"
                     /locus_tag="VQ878_000809"
     CDS             21270..21758
                     /gene="purE"
                     /locus_tag="VQ878_000809"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET3095171.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVNSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDQSIATALADFAEEQGKIAEESSNE
                     LI"
     gene            21745..22836
                     /gene="purK"
                     /locus_tag="VQ878_000810"
     CDS             21745..22836
                     /gene="purK"
                     /locus_tag="VQ878_000810"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET3095172.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDVVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKIATGGYDGHGQNVIRSADD
                     LEEAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHAPAVMLNVLGQHVEAAEKYVTENPSTHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            22846..23073
                     /locus_tag="VQ878_000811"
     CDS             22846..23073
                     /locus_tag="VQ878_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3095173.1"
                     /translation="MIQIIVNAFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            23136..24434
                     /gene="purB"
                     /locus_tag="VQ878_000812"
     CDS             23136..24434
                     /gene="purB"
                     /locus_tag="VQ878_000812"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET3095174.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ878_000813"
     CDS             complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ878_000813"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3095175.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTQTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(28740..29456)
                     /locus_tag="VQ878_000814"
     CDS             complement(28740..29456)
                     /locus_tag="VQ878_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3095176.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29804..31591
                     /locus_tag="VQ878_000815"
     CDS             29804..31591
                     /locus_tag="VQ878_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET3095177.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31588..32064
                     /locus_tag="VQ878_000816"
     CDS             31588..32064
                     /locus_tag="VQ878_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3095178.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32092..32997
                     /locus_tag="VQ878_000817"
     CDS             32092..32997
                     /locus_tag="VQ878_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3095179.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32984..33799
                     /locus_tag="VQ878_000818"
     CDS             32984..33799
                     /locus_tag="VQ878_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3095180.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33806..34210
                     /locus_tag="VQ878_000819"
     CDS             33806..34210
                     /locus_tag="VQ878_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3095181.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34509..35675
                     /locus_tag="VQ878_000820"
     CDS             34509..35675
                     /locus_tag="VQ878_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET3095182.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35791..36828
                     /locus_tag="VQ878_000821"
     CDS             35791..36828
                     /locus_tag="VQ878_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET3095183.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37035..37889
                     /locus_tag="VQ878_000822"
     CDS             37035..37889
                     /locus_tag="VQ878_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3095184.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            38039..38279
                     /locus_tag="VQ878_000823"
                     /pseudo
     CDS             38039..38279
                     /locus_tag="VQ878_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
BASE COUNT        10750 a         7406 c         9116 g        11139 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagatagtga tggggatgat agctagggtg cgcgtgagtt
      421 tgacaatggt tgcggattcg agggcattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag caagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccag
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggtgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaag aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcgggaggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ctagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggt ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga gaccttggca gctgttttac
     1801 gcaagtatga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccagac tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggctgctgg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct gggcttatgt cgactttgcc gactgtagat
     3541 gggaagggat ttgacatgct agacctcggt gccaatgcgg aaaatacagc ccagcacctc
     3601 catcaatacg cggttctagg atccttctat gctaaaaatg ttcgtggcat tgcgcaacca
     3661 cgtgttggct tgctcaataa cggaacagag agtagcaagg gcgatccgct tcgtaaggaa
     3721 acttatgaat tactagtggc tgatgaaagt ttgaacttta tcggaaatgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacaac tcaattattc agatattggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aagaaattga ccaactccaa aacgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaactccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa gcctgtaatc
     4561 atgcgctatc taaggagaga agcaaggttg agaatatctt tgccaaagta aaaacgttta
     4621 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     4681 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aatagtaaaa
     4741 aagtgattag aaaacatctt ttttaaaaat agagatgatt ttgaaacaaa aaagctaatt
     4801 caagacgttt ctatgccaat tcaagatttg gatgaaaaaa attaatagat actgttatac
     4861 taaacttgtc aagtttgtaa caagacaaat attaaaaata aaaaagaggt attcgttatg
     4921 aatacaaaaa agatgtcaca atttgaaatt atggatactg agatgcttgc ttgcgttgaa
     4981 ggtggcggat gcaattgggg agattttgcc aaagcaggtg ttggaggagg agcagtacga
     5041 ggtcttcagc taggaattaa aacaagaaca tggcaaggtg cagcaactgg tgctgcggga
     5101 ggagctatac ttggaggtgt ggcctatgca gcgacatgtt ggtggtaatt atggatttta
     5161 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta
     5221 gaaaaaaatt tttaaagtct tcggagaaga aaacagaaaa atctgttaaa aaataatcaa
     5281 aactataaat gatgaatctg aatcaaaatt attttgcgca tgtaaatagg agtcttatag
     5341 taacgagtca aaaaaggagt aactatgaat cgtaatttag aacggtgtta tctattctga
     5401 ctaggaatag atcataccag aggtagctta gaaatagcag agacattaga aattgaagta
     5461 ataaatagga tgtcgtaagt gttactatca atgatttatt tgtttcaagc ttgtctaggg
     5521 tgacagtaaa aaatcaattt cctttcaata gcatattttt agtgggcagt actcttgttc
     5581 tgcctatttt tttatccaaa aagtgcagtt gggagggaga taggctcatt tgggaaggaa
     5641 gtccagtttt tgtttagtga ttggggtaag atagttgtta tcagatgagt ttatactctt
     5701 cgaaaatcaa attcaaacca cgtcaacgtc gccttgccgt atatatgtga ctgacttcgt
     5761 cagtcctatc tacaacctca aaacagtgtt ttgagcagcc tgcggctagt ttcctagttt
     5821 gctctttgat tttcattgag tattagggaa aaggagatga atatgaaatt tgggaaacgt
     5881 cactatcgtc cgcaagtgga tcagatggac tgcggtgtag cttcattagc catggttttt
     5941 ggctactatg gtagttatta ttttttggct cacttgcgag aattggctaa gacgaccatg
     6001 gatgggacga cggctttggg cttggtcaag gtggcagagg agattggttt tgagacgcga
     6061 gccattaagg cggatatgac gctttttgac ttgccggatt tgacttttcc ttttgttgcc
     6121 catgtgctta aggaagggaa attgctccac tactatgtgg tgactgggca ggataaggat
     6181 agcattcata ttgccgatcc agatcccggg gtgaagttga ctaaactgcc acgtgagcgt
     6241 tttgaggaag aatggacagg agtgactctt tttatggcac ctagtccaga ctataagcct
     6301 tataaggaac aaaaaaatgg tctgctctct tttatcccta tattagtgaa gcagcgtggc
     6361 ttgattgcca atatcgtttt ggcaacactc ttggtaaccg ggattaacat tgtgggttct
     6421 tattatctgc agtctatcat tgatacctat gtgccagatc agatgcgttc gacactaggg
     6481 attatttcta ttgggctagt catcgtctac atcctccagc aaatcttgtc ttacgctcag
     6541 gagtatctct tgcttgtttt ggggcaacgc ttgtcgattg acgtgatttt gtcctatatc
     6601 aagcatgttt ttcacctccc tatgtccttc tttgcgacac gcaggacagg ggagatcgtg
     6661 tctcgtttta cagatgctaa cagtatcatc gatgcgctgg cttcgaccat cctttcgatt
     6721 ttcctagatg tgtcaacggt tgtcattatt tcccttgttc tattttcaca aaataccaat
     6781 ctctttttca tgactttatt ggcgcttcct atctacacag tgattatctt tgcctttatg
     6841 aagccgtttg aaaagatgaa tcgggatacc atggaagcca atgcggttct gtcttcttct
     6901 atcattgagg acatcaacgg tattgagact atcaagtcct tgaccagtga aagtcagcgt
     6961 taccaaaaaa ttgacaagga atttgtggat tatctgaaga aatcctttac ctatagtcga
     7021 gcagagagtc agcaaaaggc tctgaaaaag gttgcccatc tcttgcttaa tgtcggcatt
     7081 ctctggatgg gggctgttct ggtcatggat ggcaagatga gtttggggca gttgattacc
     7141 tataatacct tgctggttta ctttaccaat cctttggaaa atatcatcaa tctgcaaacc
     7201 aagcttcaga cagcgcaggt tgccaataac cgtctaaatg aagtgtatct agtagcttct
     7261 gagtttgagg agaagaaaac agttgaggat ttgagcttga tgaagggaga gatgaccttc
     7321 aagcaggttc attacaagta tggctatggt cgagacgtct tgtcggatat caatttaacc
     7381 gttccccaag ggtctaaggt ggcttttgtg gggatttcag ggtcaggtaa gacgactttg
     7441 gccaagatga tggttaattt ttacgaccca agtcaagggg agattagtct gggtggtgtc
     7501 aatctcaatc agattgataa aaaagccctg cgccagtaca tcaactatct gcctcaacag
     7561 ccctatgtct ttaacggaac gattttggag aatcttcttt tgggagccaa ggaggggacg
     7621 acacaggaag atatcttacg ggcggtcgaa ttggcagaga ttcgagagga tatcgagcgc
     7681 atgccactga attaccagac agaattgact tcggatgggg cagggatttc aggtggtcaa
     7741 cgtcagagaa tcgctttggc gcgtgctctc ttgacagatg cgccggtctt gattttggat
     7801 gaggcgacta gcagtttgga tattttgaca gagaagcgga ttgtcgataa tctcatggct
     7861 ttggacaaga ccttgatttt cattgctcac cgcttgacta ttgctgagcg gacagagaag
     7921 gtagttgtct tggatcaggg caagattgtc gaagaaggaa agcatgctga tttgcttgca
     7981 cagggtggct tttacgccca tttggtcaat agctagaaag aggagaggat gaaaccagaa
     8041 tttttagaaa gtgcggagtt ttataatcgt cgttaccata atttttccag tagtgtgatt
     8101 gtacccatgg cccttctgct cgtgttttta cttggctttg caactgttgc agagaaggag
     8161 atgagtttgt ccactagagc tactgtcgaa cctagtcgta ttcttgcaaa tatccagtca
     8221 actagcaaca atcgtattct tgtcaatcat ttggaagaaa ataagctggt taagaagggg
     8281 gatcttttgg ttcaatacca agaaggggca gagggtgtcc aagcggagtc ctatgccagt
     8341 cagttggaca tgctaaagga tcaaaaaaag caattggagt atctgcaaaa gagcctgcaa
     8401 gaaggggaga accactttcc agaggaggat aagtttggct accaagccac ctttcgcgac
     8461 tacatcagtc aagcaggcag tcttagggct agtacatcgc aacaaaatga gaccatcgcg
     8521 tcccagaatg cagcagctag ccaaacccaa gccgaaatcg gcaacctcat cagtcaaaca
     8581 gaggctaaaa ttcgcgatta ccagacagct aagtcagcta ttgaaacagg tgcttccttg
     8641 gccggtcaga atctagccta ctctttttac cagtcctaca agtctcaggg cgaggaaaat
     8701 ccccaaacta aggttcaggc agttgcacag gttgaagcac agatttctca gttagaatct
     8761 agtcttgcta cttaccgtgt ccagtatgca ggttcaggta cccagcaagc ctatgcgtca
     8821 gggttaagca gtcaattgga atcccttaaa tcccaacact tggcaaaggt tggtcaggaa
     8881 ttgacccttc tagcccagaa aatcttggag gcagagtcag gtaagaaggt acagggaaat
     8941 cttttagaca aggggaaaat tacggcgagt gaggatgggg tgcttcatct taatcctgag
     9001 accagtgatt ctagcatggt tgcagaaggt gccctactag cccaacttta tccatctttg
     9061 gaaagagaag ggaaagccaa actcacagcc tatctaagtt caaaagatgt agcaagaatc
     9121 aaggtcggtg attctgttcg ctatactacg actcatgatg ccgggaatca acttttccta
     9181 gattctacta ttacaagtat tgatgcgaca gctactaaga ctgagaaagg gaatttcttt
     9241 aaaatcgagg cggagactaa tctaacttcg gagcaggctg aaaaacttag gtacggggtg
     9301 gaaggccgct tgcagatgat tacgggcaag aaaagttatc tacgttatta tttggatcaa
     9361 tttttgaaca aagagtaatg ttcgtgtttt tagagttaaa taatttttaa actgtgagaa
     9421 agattcttct tgcagttttt tctttacaat ttttgaaaaa tatctactat ttattcggtt
     9481 aaattcttgt gttttttggt tttttgtggt aaaatgtgct caagtaatac gaaaggcgaa
     9541 ctttaaaatg tcaaaacaat tgatctattc gggaaaagct aaagatatct atacaactga
     9601 ggatgaaaat cttattattt caacttacaa ggaccaggcg actgctttca atggtgtcaa
     9661 gaaggagcag attgcaggta agggagtctt gaataatcag atctcatctt ttatttttga
     9721 gaaattaaat gcggctggtg tggcgactca ctttgtggag aaactttcag acacggaaca
     9781 actcaataaa aaggttaaga ttattccttt ggaagtcgtg ctccgcaact atactgctgg
     9841 ttccttttca aaacgttttg gtgtggatga aggaatcgcc ttggagactc cgattgtcga
     9901 attttactac aaaaatgatg atttggatga tccatttatc aatgatgagc atgtgaaatt
     9961 cctacagatt gcggatgacc agcagattgc ctacttgaag gaagaaacgc gtcgtatcaa
    10021 tgaactattg aaagtctggt ttgctgagat tgggcttaaa ttgattgact ttaagctaga
    10081 gttcggtttt gacaaggatg gcaagattat cttggcagac gaattttcac cagataactg
    10141 ccgcttgtgg gatgctgatg gcaaccacat ggataaggat gttttccgta gaggattggg
    10201 agaactaacc gacgtttatg agattgtttg ggaaaagttg caggaattga aataatctgt
    10261 ttgcaatgga aaaccttcgt ctctcaacta aaaggactca ggctgaaaag gtcccccaga
    10321 ccttttcact ctgtagagaa ctaggtgaac taaccgatgt ttacgaaatt gtctaggaaa
    10381 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
    10441 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
    10501 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
    10561 tattcgtatt gtgcaagtat atgatgtatt tgacttggct gaggacttgt ttgcacctgc
    10621 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
    10681 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctaccagggc agtttgacca
    10741 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
    10801 caacacagcc caactttact tggtgaataa agatattgat gtgactgagt tggaagctgt
    10861 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga cagggattgc
    10921 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgactttct ttgaaagcta
    10981 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
    11041 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
    11101 caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
    11161 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
    11221 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
    11281 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
    11341 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
    11401 ttggctcctc atgtttaaaa atgaaaccca caaccatcca acagaaattg agccatttgg
    11461 tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
    11521 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
    11581 tgctgggaaa ttgccacaac aagtcatttc taaaacagca gctcatggtt attcttcata
    11641 tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc caggctttgt
    11701 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
    11761 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggcaaaacag gtcgtgatgg
    11821 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
    11881 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
    11941 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gcgtctgtgt
    12001 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
    12061 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
    12121 ggttcgtcct gaagatgtgg atgccttcgt tgccgaatgt aacaaagaaa atattgatgc
    12181 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgaactgga atggtgagac
    12241 aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc
    12301 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
    12361 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
    12421 gactgtcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
    12481 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
    12541 tactgcgtcg gtcattgctc aaggtttcaa ctcatatgta gctgaatggt ctccatacca
    12601 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg
    12661 gtctaaggct cgtttctctt accaagaata tttcgagcgg atggacaagc aagcagagcg
    12721 ttttggtcag ccagtagccg cccttctagg ctctattgaa gctcagattc aacttggctt
    12781 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
    12841 aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
    12901 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
    12961 ttttgacttg attaagaaaa attttgctca gtttgaagca agccaagctg accataaagt
    13021 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
    13081 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
    13141 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga agattggaca
    13201 aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac acaagcttga
    13261 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc aagcgaaaga
    13321 actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag aaaaggttga
    13381 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
    13441 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
    13501 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
    13561 ctttgccggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
    13621 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggctt
    13681 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccatacgg
    13741 aaactttgaa gatgctaaca gtactagtcc aaccctcttc tacaatgatg ccaaccaaca
    13801 cgtggccaag atggtggaaa ctcgcattgc caataccaac tcaccatggt tggctggtgt
    13861 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
    13921 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
    13981 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
    14041 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag aacgttatga
    14101 ggatggtctt ttccaaaata tcccaggcaa taaagaccaa cacctgttcg catcagcggt
    14161 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
    14221 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
    14281 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
    14341 gctgctaagt tgacctactt tggactccac agtcttcaac accgtggtca ggagggggca
    14401 ggaatcctct ccaacgatca aggacaactg aagcgccatc gtgacatggg gcttttatca
    14461 gaagttttca gaaatccatc taatttggat aaattgacag gagctggtgc gattgggcat
    14521 gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccaaccctt cctcttccgt
    14581 tttcacgata tgcagtttgg tttggctcat aatggaaatc tgaccaatgc agcctctctc
    14641 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
    14701 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
    14761 agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
    14821 cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg agcggtggtt
    14881 gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggatttg tgatttgaag
    14941 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
    15001 acccagttgg cgatttgttc tatggagtat atctactttg cccgccctga ttctaatatc
    15061 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
    15121 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
    15181 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
    15241 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
    15301 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
    15361 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
    15421 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
    15481 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
    15541 gacagtctga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
    15601 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
    15661 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    15721 acagattctc cattaaagaa aaggaaaaaa taaatgacaa ataaaaatgc atatgcccag
    15781 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    15841 cgtacggaga gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgatctt
    15901 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    15961 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    16021 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    16081 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    16141 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    16201 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    16261 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    16321 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    16381 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    16441 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    16501 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    16561 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    16621 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    16681 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    16741 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    16801 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    16861 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    16921 ttgaactcaa ggagtttgag agcaaggcag actacgaagc agcccttgtc gaactcttgg
    16981 aagaacacca gattgacttg gtttgcctag caggctacat aaaaatcgtt ggaccaacct
    17041 tattgtcggc ttatgaaggt cggattgtca atattcatcc agcctacttg ccagaatttc
    17101 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    17161 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    17221 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    17281 tgtatctgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    17341 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    17401 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    17461 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    17521 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    17581 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    17641 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    17701 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    17761 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    17821 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    17881 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    17941 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    18001 caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc ttgataatgc
    18061 tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga tggacggtcg
    18121 tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg acttggatag
    18181 ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg tggtcaacct
    18241 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    18301 tatcgatatt ggtgggccat ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    18361 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    18421 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    18481 tgacgccttg attgcaaaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    18541 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    18601 ggacttttac cagaaagctt tgcctacaga ttactccatt gcttcagcca aacagctcaa
    18661 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    18721 tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat gtggaattgg
    18781 tcaagctgat gacatcgaga ctgcttggga atacgcttat gagtctgacc cagtgtctat
    18841 ctttggtgga attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg agaagatgca
    18901 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagccatttt
    18961 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    19021 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    19081 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    19141 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggcattat
    19201 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    19261 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    19321 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    19381 catccagccc ggtggctcag tccgtgacca agaatctatc gaagccgctg acaagtatgg
    19441 cttgaccatg gtcttcacag gagtgagaca ttttagacat taagaagata aaagggaaga
    19501 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    19561 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    19621 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    19681 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    19741 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    19801 ggacctttat cggcccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    19861 ctgggcttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    19921 ttgccaagga aatcatggtc aaatatggtg tttcgacagc agcctatggc acattttcag
    19981 attttgagga agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    20041 atggcttggc gcttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    20101 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    20161 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    20221 acatcatgcc aacggctcag gaccacaaac gtgcctacga tggcgacaaa gggcctaaca
    20281 cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag
    20341 cggttgacac cattgtcaag ccagttctag aagggatgat taaagaaggt cgcccttatc
    20401 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc atcgagttca
    20461 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    20521 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcacgtgg acggacaagg
    20581 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagattat tcaaagggtg
    20641 ttgagttgcc agtcaaaacc gatggtgaca tcattaccta ctatgcaggg gctaagtttg
    20701 cggaaaatag cagagcgctg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    20761 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    20821 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    20881 acgcgacgca gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    20941 tgttctggtc agggggaaac tttgagacct taggctcaaa gtttaggaat gaaaccgaag
    21001 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    21061 atacgttaat ggtcgtatgg tttgcgagcg ttagcgagct aatatggagc aattaccgcc
    21121 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    21181 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    21241 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    21301 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    21361 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    21421 aagaagcccg tagccgtggc atcaagatca tcatcgcagg tgctggtggc gcagcccatt
    21481 tgccaggtat ggtcgctgct aaaacaatcc ttccagtcat tggtgtgcca gtcaactctc
    21541 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    21601 ttgcgaccat ggctatcggt gaagcaggtg cgacaaatgc ggccctcttc gctctccgtc
    21661 tcctctcagt agaggatcag tctatcgcga cagcattggc agatttcgca gaagaacaag
    21721 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    21781 ggtcaactgg gtcagatgat ggccatttct gctatctaca tggggcacaa ggttatcgcg
    21841 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    21901 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    21961 gaaaatgtcg acgctgacgg tttggatgtc gttatcaagg atggacaact ccctcaagga
    22021 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    22081 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    22141 gacttgtcga aaaactatgt ccttaagatc gcaacaggtg gttatgatgg acacgggcaa
    22201 aatgtcattc gttcagcaga cgatttggaa gaagcctatg cattagccga ctcagcagct
    22261 tgtgtcttgg aagaatttgt caattttgac cttgagattt ctgtcatcgt gtcaggaaat
    22321 gggaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    22381 aagaccatcg taccagcccg tatttctgaa agtctagcag acaaggctaa agctatggca
    22441 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgaca
    22501 gctgatgaca tcattgtcaa tgagattgct ccacgaccac acaactcagg ccactactct
    22561 attgaagcct gtgacttttc acaatttgac acgcatatat taggtgttct gggagcacca
    22621 ttgccagcca tcaaactaca tgcgcctgcc gtcatgctta acgttctcgg ccagcatgtt
    22681 gaggccgctg aaaaatatgt cacagaaaat ccaagcaccc acctccacat gtatggtaaa
    22741 atagaagcaa agcataatcg taagatggga catgtgactt tgtttagtga tgtaccggat
    22801 agtgtggaag agtttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    22861 gttaatgcat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgctagt
    22921 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    22981 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    23041 tctgtgttta ttggaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    23101 tcccaacagc ttaagaagaa aggaaagatt aacacatgat caaccgttac tctcgccctg
    23161 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    23221 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    23281 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    23341 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    23401 actatgggtt aacttctacc gacgtggtgg atactgccta tggttacctc tacaagcagg
    23461 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    23521 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    23581 cttttggtct taaattggca acttggtata gcgaaatgaa acgcaatatc gagcgcttcg
    23641 agcatgcggc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    23701 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    23761 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    23821 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    23881 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    23941 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    24001 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    24061 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    24121 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    24181 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    24241 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    24301 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    24361 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    24421 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    24481 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    24541 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    24601 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    24661 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    24721 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    24781 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    24841 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    24901 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    24961 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    25021 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    25081 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    25141 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    25201 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    25261 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    25321 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    25381 tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag
    25441 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    25501 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtactcagcg
    25561 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    25621 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    25681 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    25741 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    25801 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    25861 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    25921 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    25981 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    26041 gttttacctg caaagaagtc catgtattta ccgataaggg cttttacaaa gttcatcgct
    26101 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    26161 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    26221 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    26281 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    26341 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    26401 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    26461 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    26521 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttcttttaga
    26581 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    26641 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    26701 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    26761 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    26821 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    26881 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    26941 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    27001 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    27061 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    27121 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    27181 ttaaaagcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    27241 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    27301 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    27361 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    27421 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    27481 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    27541 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    27601 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    27661 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    27721 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    27781 tagccataat gtttcgcttt atcgatgatt tccttgagtt gttctggtga gaaatattta
    27841 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    27901 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    27961 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    28021 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    28081 gtttgagtta ccacctctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    28141 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    28201 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    28261 tgaggggaat cagaaactgt atggatggtc ggttggtttt ctgtagtagt agtaactcca
    28321 tcggctgcaa cagtctgtgc ttggaaggca aatccaatta gaacagaagc tgctcctaca
    28381 gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt tcattgcaaa acctcctgat
    28441 tgcattgtta tattgatagc gattatataa atcaacgcct ttattttatt tcttatatta
    28501 acgagagtca agaggagatg acaaaaaact ataataagta taaaaaaata taaaatttaa
    28561 gcttaagatt tcagattggt cggaaaaaat acgtatatat atctagtata atttttggtt
    28621 ctatttctat aaaatattcc acaaattata gaatcttcca aaaataggta agcgctacct
    28681 ttttggtgtg gtataataag catagaaaaa gcccgagcga ttaggctcag gctttcttct
    28741 tagtgatcac ggtcacatga gatgaattta atcttgtagt aatcagatcg tttgtaagtt
    28801 tcactgtatt ctaaaacttg gccagttgat tcgagtttgg tgattttagt ttgtaggaca
    28861 gtagggaatt gttcatcgac tccgaggact gaagccgcat gttctggagt tggaaagact
    28921 atttcgttga tttcttcaaa gtgttcatca ttcatgtgaa tgtggtagtc taacttgaaa
    28981 cgattataga tagaactata gtattcaagg tttggataat ttgcgttgat atattgttct
    29041 gggatgtagg atgtatggta gatataaacg acaccgtttg attcgcggat acgttcaatc
    29101 ttgtagtaga attgatcgcc gcgtagaccc aatttttcca ggtaaacaag cttgtttccg
    29161 cgttcaattg aaagaacagt taccttatca tctttagcat tgaagagttc aatatctgaa
    29221 aactctacaa gcttgtgttt gcgtgcacgt gaaacgaagg ttccttttcc ttgttggcgg
    29281 acaatatagc catctttggc aaggtcgttt aaggcgcgaa caactgtgat agagctgaca
    29341 tcgtacattg aaatgagttc tgcttcagta taaaatttat ctccactgct aaactgccca
    29401 gagatgattt tattttttaa ttcgtctttt atgtattgat atttgggaat tgccatattt
    29461 ttacctctat tttccttctc catagaaaat tttaccataa aagcgaaaaa aatagtagtc
    29521 ttttgaataa aaaattagaa taatagtttg aaaaattaag ctatataggg attgatcata
    29581 ttttataaat gtattctata caaaattatt ttaggtccta tattccagat ttaaagagcg
    29641 tttgaaatgg gtctaaaaat gtttgaaact aattgaatgt gtgtataata gtaaaaatgc
    29701 agtaaatatc ccgacaattt ctattgacag ttcaaacaga ttggtttata attaatataa
    29761 caacaaatga aagcgcaaac tttcgcggtc ggaaggtagt tttatgacac gatttgagat
    29821 acgagatgat ttctatctcg atggaaaatc atttaagatt ttatctggtg ccattcatta
    29881 ttttagggtt cctccagagg attggtatca ttcgctctat aacttgaagg ctcttggttt
    29941 taatacggta gagacttatg ttgcttggaa tttacacgag cctcgtgaag gtgagtttca
    30001 ttttgaaggt gatctggatt tagagaaatt tctccaaata gcgcaggatt tgggtctcta
    30061 cgcaattgtg cgtccgtctc catttatctg tgcggaatgg gaattcggtg gcttaccagc
    30121 ttggctcttg accaagaaca tgcgaattcg ctcatctgac ccagcatata tcgaggcagt
    30181 tggtcgctac tatgatcagt tattgccaag actggtgcct cgtttgttgg acaatggtgg
    30241 caatattctc atgatgcagg ttgaaaatga gtatggttct tacggagaag ataaggctta
    30301 cctgagagcg attcgacagc taatggaaga gtgtggcgta acctgtcccc tctttacatc
    30361 agatggtcca tggcgagcta ctctgaaagc tggaacctta attgaagagg acctctttgt
    30421 aacaggaaac tttggttcta aggcacctta caacttttcg cagatgcagg aattctttga
    30481 tgaacatggt aagaaatggc cactcatgtg tatggagttc tgggatggtt ggttcaatcg
    30541 ctggaaagaa ccgattatca cacgggatcc taaggaattg gcagatgcag ttcgagaggt
    30601 tttggaacaa ggctctatca atctttacat gttccacggt ggtacaaact ttggtttcat
    30661 gaatggttgc tcagctcgag gaactttgga cctgccacaa gttacgtctt atgattacga
    30721 tgcccttctg gatgaagaag gaaatccaac tgctaaatat cttgcagtca agaagatgat
    30781 ggcaacacat ttttcagagt atccgcagtt ggaaccactc tacaaagaga gtatggagtt
    30841 ggatgctatt ccactagttg aaaaagtttc tttgtttgaa accttagata gcttgtcaag
    30901 tcctgtagaa agtctctatc ctcaaaagat ggaggagctg ggacaaagtt atggctacct
    30961 actttatcga acagaaacaa actgggatgc agaagaagaa agacttcgta tcattgatgg
    31021 tcgagatagg gcccagctgt atgtcgatgg tcagtgggtt aaaactcaat atcagacaga
    31081 gattggggaa gatatttttt atcaaggtaa aaagaaaggg ctatctaggt tagatatctt
    31141 gatagaaaat atggggcgtg tcaactatgg gcataagttc ttagcggata cgcaacgtaa
    31201 gggaattcgg acaggggtct gtaaggatct gcatttctta ctaaactgga aacactatcc
    31261 actcccacta gacaatcctg agaaaattga tttttcaaaa ggatggactc aaggacaacc
    31321 agccttttac gcttatgact ttacagtcga agagccaaaa gatacttacc tagacttgtc
    31381 tgagtttggt aagggggttg cctttgtcaa tgggcagaat ctaggacgtt tttggaacgt
    31441 tggcccaact ctctcacttt atatccctca tagctatctc aaggaaggtg ccaaccgcat
    31501 cattatcttt gaaacagaag gtcaatataa agaagagatt catttaactc gtaaacctac
    31561 actaaaacat ataaaggggg aaaacttatg acaattgtag gatgccgtat tgatggacgt
    31621 ttgatccacg gacaagtagc caatctttgg gctggaaaac taaatgtttc acgcattatg
    31681 gttgtagacg acgaagttgt caacaacgat attgaaaaga gtggtttgaa acttgcgaca
    31741 ccaccaggtg tgaaattgag tattttgcca gttgagaaag ctgcagccaa tattcttgct
    31801 ggcaaatacg atagccaacg tctctttatc gtggctcgta aaccagaccg cttccttggt
    31861 ttggtagaag caggtgtacc acttgaaacc cttaatgttg ggaatatgtc tcaaacacca
    31921 gaaactcgtt ctattacacg ttctatcaac gtagtagaca aggatgtgga agacttccac
    31981 aaactggcag aaaaaggtgt taaacttact gctcagatgg ttccaaatga tccaatttca
    32041 gactttttga gcttattaaa ataggaaaaa aatttttagg aggtcattgt tatgatacaa
    32101 tggtggcaaa ttttacttct cactttgtac tcagcttatc aaatctgtga tgagttgacg
    32161 atcgtttcat ctgcaggttc ccctgtattt gctggtttca ttactggttt aatcatggga
    32221 gatgtgacta ctggtttact tatcggtggt aacttgcaac tgttcgttct tggggttggt
    32281 accttcggtg gtgcttctcg tatcgacgca acttctggtg cggttcttgc gacagccttc
    32341 tctgtttcac aaggaattga tgcaccgctt gccattacta caatcgctgt accagtagca
    32401 gctctcttga cttacttcga cgttcttggt cgtatgacta ctaccttctt cgctcaccgt
    32461 gtggatgctg caatcgaacg ctttgactat aaaggtattg aacgcaacta cttgcttggt
    32521 gcgattccgt gggctctatc tcgtgccctt ccagtcttct ttgcccttgc ttttggtggt
    32581 gcctttgtac aatcagtagt agacttcgtt gaagcctaca aatgggttgc agatggcttg
    32641 acacttgcag gacgtatgct tccaggtctt ggatttgcaa tcttgcttcg ttaccttcca
    32701 gttaaacgta accttcacta ccttgctatg ggatttggtt tgacagctat gttgactgtt
    32761 ctttactcat atgtaacagg tcttggtggc gctgttgctg gtatcgtagg tactcttcct
    32821 gctgaagttg ctgaaaaaat tggtttcgtg aacaacttca aaggtttgtc tatgattggt
    32881 atttctatcg taggtatttt ccttgcagtg cttcacttca aaaatagcca aaaagtagct
    32941 gtagcagcac cttctacacc atcagaaagt ggggaaatcg aagatgacga attctaatta
    33001 caaacttaca aaagaagatt ttaatcaaat caacaaacgt agcttgttta ctttccaatt
    33061 aggttggaac tacgaacgta tgcaagcttc tggttacctt tacatgatct tgcctcagtt
    33121 gcgtaaaatg tatggtgatg gaactcctga attgaaagaa atgatgaaag ttcatactca
    33181 attcttcaat acttcaccat tcttccatac cattatcgct ggttttgacc ttgccatgga
    33241 agaaaaagat ggtgtaggtt caaaagacgc cgttaacggt atcaagacag gtttgatggg
    33301 accattcgct cctcttgggg atacaatctt tggttcactt gtacctgcta tcatggggtc
    33361 agtcgcagca actatggcta tcgctggcca accttggggg atcttccttt ggattgcagt
    33421 tgcagtagcg tatgacatct tccgttggaa acagttggaa tttgcttaca aagaaggggt
    33481 taaccttatc aacaacatgc aaagtacctt gacagctttg attgacgctg catctgtact
    33541 tggtgtcttc atgatgggtg ctcttgtagc aacagtgatt aactttgaaa tttcttacaa
    33601 gttgccaatc ggtgaaaaga tgattgattt ccaagacatc ttgaaccaaa tcttcccacg
    33661 tttgcttcca gcaatcttta ctgcctttat cttctggttg cttggtaaga aaggtatgaa
    33721 ctctactaaa gctatcggta ttattatcgt acttgctttg gctctttctg cccttggtca
    33781 ctttgcactt ggaatgtaat tccttatgac taaatcatta attttggtga gccatggtcg
    33841 cttctgtgag gagcttagag gtagcacaga aatgattatg ggcccacaag acaacattta
    33901 cacagtagct cttcttccag aagatggccc agaagaattt actgctaaat ttgaagctgt
    33961 tattgaagga ttggatgatt tcctagtctt tgcggatctt ctcggtggga caccttgtaa
    34021 tgtggtgagt cgcttgatca tggaaggtcg tgatattgac ctttacgcag ggatgaatct
    34081 tccaatggtg attgaattta tcaatgcgag ccttacaggc gcagatgcgg actacaagag
    34141 ccgtgctgca gaaagcattg tgaaagttaa tgacctgtta gcgggcttcg atgatgacga
    34201 agatgaataa tactcttcga aaatctcttc aaactacgtc aacgtcgcct tgccgtaggt
    34261 atatgttact gacttcgtca gtcttatccg gcaacctcaa aacggtgttt tgagctgact
    34321 tcgtcagtct tatccggcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
    34381 acagatttta gttggaactc gattcaattc atgtgacaac gtgaaaatcg ttagagcatt
    34441 ttatatagaa tatacatggg aatgtagctt actcccattc ccatatttaa tagaaaaaga
    34501 ggaactcaat gctacattat acaaaagaag acttgctcga attgggtgca gaaatcacta
    34561 cgcgtgaaat ctaccaacag cctgatgtat ggagagaagc ttttgaattt tatcaagcaa
    34621 aacgtgaaga aattgcagcc ttcctacaag aaatcgctga taaacatgac tatattaagg
    34681 ttatcttgac aggtgctggg acttctgctt atgtgggaga taccttgcta ccttatttta
    34741 aggaagtcta tgacgaacgc aaatggaatt tcaatgctat tgcgacaaca gatatcgttg
    34801 ccaatccagc aacctatttg aaaaaagatg tggcaactgt ccttgtgtct tttgctcgta
    34861 gtgggaactc gcctgaaagt gtggcgactg ttgatttggc caaatccttg gtggatgagc
    34921 tttatcaagt gacgattact tgtgcagcag atggtaaatt ggctcttcaa gctcacggtg
    34981 atgaccgtaa tctcttgctc ttgcaaccag ctgtctctaa tgatgctgga tttgccatga
    35041 cttctagctt tacgtctatg atgttgacag ctctcttggt ctttgatcct acagaatttg
    35101 ctgttaagtc tgaacgtttt gaagttgtat ctagtcttgc ccgtaaagtt ttagacaagg
    35161 cagaagatgt caaagagctt gttgatttag actttaaccg tgtcatctat ctaggcgctg
    35221 gtcctttctt tggacttgct catgaagctc agctcaagat tttggaatta actgctggtc
    35281 aagttgcgac catgtatgaa agcccagttg gcttccgtca cggtccaaaa tctcttatca
    35341 acgacaatac agttgttttg gtctttggta caacgacaga ctacactcgt aagtatgact
    35401 tggacttggt tcgtgaagtt gctggtgacc agattgctcg tcgtgttgtg cttttgagtg
    35461 atcaagcttt tggtcttgaa aatgtcaaag aagtggccct tggttgtggc ggtgtcttga
    35521 atgatattta ccgtgtcttc ccttacatcg tttatgccca actctttgcc ctattgactt
    35581 cactcaaggt agaaaataaa ccagatacac cgtctcctac aggtacagta aaccgtgtag
    35641 tacaaggtgt cataattcac gaatatcaaa agtaagacag tgtttatgaa ttcttgacaa
    35701 gaggatttgt aaattatcag ataaaccata gattgtcagt acgctttcta tggtttgttt
    35761 gcttgagaga aatagtaaaa ggagaacaga atgaaagcat acacagagcg tgtatttgga
    35821 aatgttgagg gcgaggatgt cttggcctat cgatttgaga cagacggtgg ctaccaactt
    35881 gaggttatga cttatggcgc gaccatcttg cgctatgtcg cacctgacaa ggctggaaat
    35941 tttgccaatg ttatcttggg atttgatgac tttgatagtt atgtaggcaa tagtcccaag
    36001 catggagcaa gtgtaggtcc tgtagcgggt cgtattgcag gtgcgacctt tgagctcaat
    36061 ggtaagacct atgaccttga ggttaataat gctagcaact gtaatcacag tggttcaact
    36121 ggttgggatt ccagcttgtt tgaagttgaa gaagtaagcg atcatggctt gactctctac
    36181 acagagcgta cagatgggac aggagggttc cctggaaatc tcaagatttg gatcagttat
    36241 cacttggaag aaactggtgc ctatgaaatc agctacaagg taacgaccga tcaggatacg
    36301 ctggtcaatc caaccaacca cagctatttc aacttgtctg gtgatttcac gcagacgatt
    36361 gaccgtcatg tcttccaact aaacacagag ggcatttact caatcgctcc tgacggtgtt
    36421 cctgccaaaa ctccagaagc caaccgtgat gtggtcaaac acgtctacaa tggtaccttg
    36481 ttgaaggata tctttgcaga agaagatgag caaatccagc tggcatcagg tttggatcat
    36541 ccatttgccc ttcctgcagg ccatgacaat gctggattcc tttatgacca aaattcaggt
    36601 cgcttcctgc ttttcaagac agaagctcct tgctttgtgg tctacacagc aaactttgtg
    36661 gatgaaagtg tcatcatagg aggtcagcca atgctacagc acaatgggat tgctcttgaa
    36721 gcgcaagctt taccagatgc cattcacagt gaccttaaag gccaagtcat tcttaaggct
    36781 ggtcaaacct tcaccagtaa gacacgttat gaacttgttg tgaaataaaa aagctggtca
    36841 aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt gatactatgc
    36901 gttttgttat gaaatgattt actttatctt atcctgaaat ggtgttattt ttgagttatc
    36961 tggcttgact ttcttgatgg aaattatata atagttgtaa caataataat tacaacgaga
    37021 aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca gagacagttt
    37081 taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt ggtttagaaa
    37141 tcttatctca aactgagaca gagtccattc taggccttgg tggaaaagtc ttggtacagc
    37201 tgattcaagc acaagagagc ggagaagtga gggaacatta tggtctttac catttggcca
    37261 ttctcttacc cacacgcaag gctttggctg atgtcttgaa acacctgaca gatttacaga
    37321 ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg gaagatttgg
    37381 agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat attcgagaag
    37441 atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat gagttggggg
    37501 aaagagtaga gccctttatc ctggcagaag gtacgagaat ggggcatatt catctttcag
    37561 tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta gaggataaat
    37621 tcagtgtgcc tagcgctagt tggattgcgg ctggagatta ccatcatcat ttagcagtta
    37681 acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt ttagcctact
    37741 atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga gcacaagaag
    37801 ttgacgcacc aatcaaatgg atgacatcga gccaattgga aatcacagac tcagatggca
    37861 tcgtgacctg tattcgttta gcaaggtaaa attaggaatt tttaataagt tataagtatt
    37921 gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga tgggtgagaa
    37981 ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg aaaaagaaat
    38041 gacaaattca aagtatatta ctcgtttgaa acgttcagag ggccagttgc gtgggattca
    38101 aaagatgatt gaaggagatc gtgacgcaac tgacagcagt gagatctagt gtagagcgcg
    38161 tgattgagat gataattacc gaaaatctta ctgaatgtat caatcagcca ctagatgatt
    38221 ctgaagctca aaaggaacgc ctagaaaagg ctatccgata cttgattaaa cggaaataaa
    38281 tgaatgtttt gagacgatat gtgcaaaggt ctattaacta ttagaatagt ttaatgtgag
    38341 tcaaaagaag ttgtaaaaaa tctttaaaat taaaaaaacg catagtatca ggtgttgaat
    38401 gtactgaccc c
//
LOCUS       DAVBOM010000015        38141 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBOM010000015 DAVBOM010000000
VERSION     DAVBOM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.015"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(331..1179)
                     /gene="dprA"
                     /locus_tag="VQ878_000824"
     CDS             complement(331..1179)
                     /gene="dprA"
                     /locus_tag="VQ878_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET3095185.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1277..1966)
                     /locus_tag="VQ878_000825"
     CDS             complement(1277..1966)
                     /locus_tag="VQ878_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET3095186.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            complement(1978..2856)
                     /locus_tag="VQ878_000826"
     CDS             complement(1978..2856)
                     /locus_tag="VQ878_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET3095187.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2846..3715)
                     /gene="licA"
                     /locus_tag="VQ878_000827"
     CDS             complement(2846..3715)
                     /gene="licA"
                     /locus_tag="VQ878_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET3095188.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLVKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLVEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3732..4754)
                     /locus_tag="VQ878_000828"
     CDS             complement(3732..4754)
                     /locus_tag="VQ878_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3095189.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4759..5466)
                     /locus_tag="VQ878_000829"
     CDS             complement(4759..5466)
                     /locus_tag="VQ878_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET3095190.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5802..7289
                     /gene="tacF"
                     /locus_tag="VQ878_000830"
     CDS             5802..7289
                     /gene="tacF"
                     /locus_tag="VQ878_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET3095191.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7299..8102
                     /locus_tag="VQ878_000831"
     CDS             7299..8102
                     /locus_tag="VQ878_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3095192.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8104..8913
                     /locus_tag="VQ878_000832"
     CDS             8104..8913
                     /locus_tag="VQ878_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3095193.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9188..12364)
                     /gene="carB"
                     /locus_tag="VQ878_000833"
     CDS             complement(9188..12364)
                     /gene="carB"
                     /locus_tag="VQ878_000833"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET3095194.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12677..13756)
                     /gene="carA"
                     /locus_tag="VQ878_000834"
     CDS             complement(12677..13756)
                     /gene="carA"
                     /locus_tag="VQ878_000834"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET3095195.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEKARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13806..14729)
                     /locus_tag="VQ878_000835"
     CDS             complement(13806..14729)
                     /locus_tag="VQ878_000835"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET3095196.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14748..15269)
                     /gene="pyrR"
                     /locus_tag="VQ878_000836"
     CDS             complement(14748..15269)
                     /gene="pyrR"
                     /locus_tag="VQ878_000836"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET3095197.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15480..16109)
                     /gene="nth"
                     /locus_tag="VQ878_000837"
     CDS             complement(15480..16109)
                     /gene="nth"
                     /locus_tag="VQ878_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET3095198.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16109..16651)
                     /locus_tag="VQ878_000838"
     CDS             complement(16109..16651)
                     /locus_tag="VQ878_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET3095199.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            17376..18935
                     /locus_tag="VQ878_000839"
     CDS             17376..18935
                     /locus_tag="VQ878_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3095200.1"
                     /translation="MHYEHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            complement(18979..19878)
                     /gene="htpX"
                     /locus_tag="VQ878_000840"
     CDS             complement(18979..19878)
                     /gene="htpX"
                     /locus_tag="VQ878_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET3095201.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19880..20440)
                     /locus_tag="VQ878_000841"
     CDS             complement(19880..20440)
                     /locus_tag="VQ878_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET3095202.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20534..21247
                     /gene="rsmG"
                     /locus_tag="VQ878_000842"
     CDS             20534..21247
                     /gene="rsmG"
                     /locus_tag="VQ878_000842"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET3095203.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            21501..22784
                     /locus_tag="VQ878_000843"
     CDS             21501..22784
                     /locus_tag="VQ878_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET3095204.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(22979..24550)
                     /gene="ffh"
                     /locus_tag="VQ878_000844"
     CDS             complement(22979..24550)
                     /gene="ffh"
                     /locus_tag="VQ878_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET3095205.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPN
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(24562..24894)
                     /locus_tag="VQ878_000845"
     CDS             complement(24562..24894)
                     /locus_tag="VQ878_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET3095206.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(24985..25362)
                     /locus_tag="VQ878_000846"
     CDS             complement(24985..25362)
                     /locus_tag="VQ878_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET3095207.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            25434..26738
                     /locus_tag="VQ878_000847"
     CDS             25434..26738
                     /locus_tag="VQ878_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET3095208.1"
                     /translation="MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            26751..27557
                     /gene="yidA"
                     /locus_tag="VQ878_000848"
     CDS             26751..27557
                     /gene="yidA"
                     /locus_tag="VQ878_000848"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET3095209.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            27600..28598
                     /locus_tag="VQ878_000849"
     CDS             27600..28598
                     /locus_tag="VQ878_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET3095210.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LATSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(28764..28835)
                     /locus_tag="VQ878_000850"
     tRNA            complement(28764..28835)
                     /locus_tag="VQ878_000850"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28800..28802),aa:Arg,seq:cct)
     gene            complement(28877..29224)
                     /gene="rplS"
                     /locus_tag="VQ878_000851"
     CDS             complement(28877..29224)
                     /gene="rplS"
                     /locus_tag="VQ878_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET3095211.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(29343..29672)
                     /gene="crcB"
                     /locus_tag="VQ878_000852"
     CDS             complement(29343..29672)
                     /gene="crcB"
                     /locus_tag="VQ878_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3095212.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQVSKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(29666..30040)
                     /gene="crcB"
                     /locus_tag="VQ878_000853"
     CDS             complement(29666..30040)
                     /gene="crcB"
                     /locus_tag="VQ878_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3095213.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(30037..30303)
                     /locus_tag="VQ878_000854"
     CDS             complement(30037..30303)
                     /locus_tag="VQ878_000854"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET3095214.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(30419..30862)
                     /locus_tag="VQ878_000855"
     CDS             complement(30419..30862)
                     /locus_tag="VQ878_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET3095215.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            30966..31901
                     /locus_tag="VQ878_000856"
     CDS             30966..31901
                     /locus_tag="VQ878_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET3095216.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVSAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            31955..32239
                     /locus_tag="VQ878_000857"
     CDS             31955..32239
                     /locus_tag="VQ878_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET3095217.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(32296..32874)
                     /locus_tag="VQ878_000858"
     CDS             complement(32296..32874)
                     /locus_tag="VQ878_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET3095218.1"
                     /translation="MVRNYWKARSWLLVLALSFLILSPVGAQESLSSYFVKITDTSKA
                     VKNGNQSEAQKLVQEMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(32849..33861)
                     /locus_tag="VQ878_000859"
                     /pseudo
     CDS             complement(32849..33861)
                     /locus_tag="VQ878_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(33864..34320)
                     /locus_tag="VQ878_000860"
                     /pseudo
     CDS             complement(33864..34320)
                     /locus_tag="VQ878_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            34852..36198
                     /gene="gdhA"
                     /locus_tag="VQ878_000861"
     CDS             34852..36198
                     /gene="gdhA"
                     /locus_tag="VQ878_000861"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET3095219.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGIICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(36694..36864)
                     /locus_tag="VQ878_000862"
     CDS             complement(36694..36864)
                     /locus_tag="VQ878_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095220.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(36877..37518)
                     /locus_tag="VQ878_000863"
     CDS             complement(36877..37518)
                     /locus_tag="VQ878_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3095221.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT        11590 a         8149 c         6870 g        11532 t
ORIGIN      
        1 tcactatact ttcccttata ctcaatgaaa atcaaagcgc aaactaggaa gctagccaca
       61 ggttgctcaa agcactgctt tgaggttgta gataagactg acgaagtcag ctcaaaatac
      121 tgttttgagg ttgcagatgg aagctgacgt agtttgaaga gattttcgaa gagtattata
      181 tgagaaaaat cctctactct actaatccac ttagaaaaaa cgcatattat caagtgttaa
      241 aaacttgcta atatgcgttt tattatggaa atgttgggtt cattttctct taaaattgat
      301 tttttcttag aattttagct taggtcattt ttaaaattca aattccgcaa gaacatcttg
      361 cccactggtg accaattttg ctccttcttg aatcaaatga tggcaaccgt ctgatagtcc
      421 atctaaaatg ctaccaggaa tagcaaagac atcgcgtcct tcttccattg ctcgctcaca
      481 cgtaatgaga ctacctgaac gcatcttagc ctctgctaca atcacaccac gacaaagtcc
      541 agcaatgatg cgattacggg caggaaaatg aaatttcaga ggttgttcgc caggtccata
      601 ttcacttaga accagatggt cattgccgat gtagtcttgc aagcgtttat tggctttagg
      661 ataaaacaca tccagtcctg ttccaatcac tgcaatggtt tttccgccat tctgaagagc
      721 tgccatatga gctgctgtgt caatgccctt ggccagacca ctgacaataa ccagttcatt
      781 ttccaagcct tgaatgactt tttcaactga tttagctccc tgtttgctac aagcacgact
      841 gcccacgacc gctaccttcg ggaatttcag gaggtcaaga tttcccttgt aaaataaaag
      901 tacaggcgca tcatatattt cactcaaatc ccaaggataa cagtcatcta aaatagagaa
      961 agatggaaat ttttgaaact ctttcgacaa atgcgcatcg tctatctgaa aataacgttc
     1021 cataaaaacg gctggattac ggcaacctga tatatctgca atatcaccca acaaaagctc
     1081 ctgatcaaca ttttcaccgt attctagaac tttcaaaatc tgttgattgg tcaaacctga
     1141 tttttttaac ttatagattt catagtttgt gattttcata aataactcca tttctttttc
     1201 tactcatcta tctattcgta aaagttcgta aaaaatcaaa aaaacatccg actattttgt
     1261 cagatgttgg aagcttttaa ttttcgtttt taagaatttc ttctaattta tgatagtctt
     1321 ggacactatc aatctcataa atgctattgc cttctaattc ttcaacatag acatctagct
     1381 ctttgatgtt atccttaacc atattgtccc aatagagatc aacaaattcg ccgcttgcat
     1441 aagccttatc gataaagctg acaatctttt ctgctgttgg agcatcccag aaggatacac
     1501 cactaaggat gcgacctgcc ttgctatcaa caataatgtt ttgaaccttg tagtcatctc
     1561 catagaccaa gaaccattcg ttggtacaat cttcacgata gacactaaaa taagtagaac
     1621 gtgtcaaatc attgcggaac atatttttaa agagatagtt atcggcatcg ataacataac
     1681 tattggctaa ttcttctttt acaagataga gagagtaaaa gttattgtag tcagcgtatt
     1741 tatcattgaa aacgagacga acaccgtatt tctctttcaa gtaatcgaat tgttctttaa
     1801 gataaccaac aatgatgatg atgtcattga ttcctttttc tttgagaaac tcaatttggt
     1861 attcaatcaa aggtttttga ttaacctgaa ccaaggcttt aggggtattt tcagtcatag
     1921 gacgcaagcg agttcccaat cccgctgcta agatgatggc tttcacacga atctccttta
     1981 ttctttaata ataatataaa ctccagcaat gacgacaagt gacgtcataa ttgtcagcat
     2041 atctagcggt gcacccaaga aaacaactgc aaacaagact gtccatacta catagctcac
     2101 gttcaagcct gtagccttgg ctggttgcaa gcgattgata gcgatataat aagccaagta
     2161 ggaaatcata tcaaaggctg caaaaacaat catgagacct agcaattgtc cattggctac
     2221 tgcagtaaat gactgatgag agaagagcac aatcacaaga taggacaaga acgaagtcac
     2281 ttgacggatt aagagggctt cgatttcact cagttcactt tccatagcaa aggagctaag
     2341 aacactctca cttccccatg caatagcaca aaccaaagca cagagaatcc caatgtagaa
     2401 ggaattaacc tgttcaacct tataggtctg ggcaataatc cctccaataa tcaagacaat
     2461 cccaaataca gtatttttcg aaatcttgtg cttcaaaaag aagaaagcca atagaactga
     2521 aatcgcaggg taaatagccg atacagatga agctaaagaa cttccgatat acttaactgc
     2581 ataaagattg gcctgcatac cgatagggcc tgctagcaag gctccgatga taacactgac
     2641 attgcgaata tttaagaaaa ttgagaggcg aactttccct tcttttacca agagaaaagc
     2701 tagtaagata aagatgctca aaaaatcatg agctgcagcc accacaaagg gtgacaaatc
     2761 tgtaaaaatc gaaaagatat aagcactaac cgttagaccc aagccccaga aaatacctga
     2821 tagaaggcca aaaggaactc cgtttttact tttcatctga acctccataa gaagccaaac
     2881 ctttaacagc tctttggtaa cgattcacac catagtcacc aaaatcttca ccttgctctt
     2941 ccttatatac agtccataga ctccaaatag tatcttgtaa aattttataa atagcaatct
     3001 tttcatgaga aaccggtgtt tggtcactct catagtgaga taagaaagtt tcttcctctt
     3061 gggaagtgaa ttcagactct aaaaagaggg cagccaaatc ccacattgga tcattcattg
     3121 atgaatattc ccagtcaatc aaataaagtc gtccttgagg tgattcgata aagttttcag
     3181 gcaccaaatc gatatgacaa gattttctgt caacacctaa gtcagccagt cttttctcta
     3241 aggagaagac tgcatttcta acagattcat agttggcata aggaatttgt tcttcaacca
     3301 aggattcgta ttttttgatt tcttcaaaag gagcaaattc tcctcttaat tccttagcag
     3361 atgtatgaat agtttgtaat attggagcaa ttttgtcgaa cttggtcttg attgacgttg
     3421 aatcaagcgt aatcgcagat tcgatatact catttacttt gataccagct tcaatatcaa
     3481 aaagataatt ttttacatct aagcctaaat cctttagtag ttcaagattg tacttttcat
     3541 cttgtcgatt gataagcttt tctgtccctt taccaaagaa tttaacaatg tattgcttat
     3601 ttgttgtttt gaccaaatag ttttgattgg tcattccacc cagttgttca acactgagga
     3661 cttcctcttc ttgactaagt aaggaagaaa ttttttcttt aatgattttc tccacaatta
     3721 acctccagta cttatacttc ccacttaaac actgttttaa aggctgtgtt taaatcggtt
     3781 gcaaagacac gatgaatatc tttaatttct cttacaggtt cttctagata aaggatattt
     3841 ttaagacgat tggcaaattt cttgacttcc atcatttgga tagcattttt aaaatcaatg
     3901 cgaccagaac gagatgaccc aaccaaaatc aagccctttt ctaaggcatc gcgagtattg
     3961 agattgactt tatattcgct aactcccatc atgagaatcg ttccctgagg acgaatgtag
     4021 cgaatcaagt cattaatagc tggtccagta ccatcaccac cacaacattc aaaagcatgg
     4081 tcaaaggcca actcttcagg aatattatcc gtaatatagc attctttggc aaatgagaag
     4141 agttccaact tttcccaatg acgaccaata accacaatct ctgattctgg caaagtatag
     4201 ttgataatat tggcaaccac aaaagctaaa cttccatctc caataacggc gatccgctcc
     4261 cgcttgctat gagcaagagt caatagacga ttcatagcgt gcatgcccac actgacaaac
     4321 tctgtaatgg ctgcaaccgt atcttcaata gcatcataag ccaccacacg atctttaggg
     4381 agagaaacaa actctctcat aaagccatca aatccactag acaagaaatg ggtccctgtc
     4441 atgtagtttt catagaattc ttcatcactc tgcataggag actgattggg aatcatgaca
     4501 actttttgac caacctcgta ggttccggtc gggtcagaaa tgacggttcc acatgactcg
     4561 tgaatcattg ccattggaag ctttttattc aaaatcttgg gatcacgttt tccctgatag
     4621 taacgctgat ccgcatgaca gacagccatg tagttgggac ggataaggat atgattctct
     4681 tggtcaatag cctcttcctg atatttgaca ttgataaact taggcttagt tagttgataa
     4741 atttgattaa tcattttact agtctttctc aatcatactt tttgcaatct tcaaatctgt
     4801 tacggttgta atcttcagat ttgagtattc acctttggcc aaggccacat cttttccttt
     4861 gatcacaaag attttacatg catctgtcaa gatttccttc tcttcatcag aaagagatcc
     4921 ataaaggtcc atgaagtcct tgcaacggaa tgtttgaggt gtttgtcctt gataaaggtg
     4981 agcacgattt ggaatatctg taataaattg accattggta ctttcaacga tagtatcaac
     5041 tgcttctacc actgtgtcca ctgcgtcatg attttgggca agttggatat tgtcctgaat
     5101 catgcgaagt gtaataaatg gacgaacaga atcgtgggta acaacgatat cctctggagt
     5161 aagcggacga taagcatcaa tggcttcaat gattttctta atacttgtat tgcggtcagc
     5221 accacccttt gtaatgatga tacgttcctt ataaagagga agatatttat ctacaagatc
     5281 ttctgcatga gaaacccagt ctccatgaac accaactaca attttttcaa tacttggctc
     5341 caagacaaat ttttcaattg tatgaatcaa aataggtcga tcacctagct ctaaaaattg
     5401 ttttggcaag ttactgatcc ccatgcgtgt gccagttcca ccggcaagaa ttcctgcata
     5461 aatcatctat tttctccttt gtcttactaa aaaaacttat tctctctatt ataccacaat
     5521 ctagtcctat cataaaagaa atactggtcc tccccttcta gaataggaga attatgcagt
     5581 tctattattc aaagaaacta gtccatttct agtaatgact aggaattctg tagcaattac
     5641 taataaatgg ctgcgaaatt ttagagtcct tcagaataat atactttcct taaagaaaac
     5701 ttaaaactta agatttgaaa cttcaaagtg attacttgac ttactgccct tcatttctta
     5761 ttagctaact ttatgatata atgaaaaacg aggtaaattg aatgaaaagt ataaaattaa
     5821 atgctctatc ttacatggga attcgtgtct tgaatattat ttttcccatc ctaactggaa
     5881 cctatgtcgc gcgtgtcttg gaccgaactg actatggtta cttcaactca gtcgacacta
     5941 ttttgtcatt tttcttgccc tttgcaactt atggtgtcta taactacggt ttaagggcta
     6001 tcagtaatgt caaggataac aaaaaagatc ttaacagaac cttttctagt cttttttatt
     6061 tgtgcatcgc ttgtacgatt ttgaccactg ctgtctatat cctagcctat cctctcttct
     6121 ttattgataa tccaatcgtc aaaaaggtct accttgttat ggggattcaa ctcattgccc
     6181 agattttttc aatcgaatgg gtcaatgaag ctctggaaaa ttacagtttt ctcttttaca
     6241 aaactgcctt catccgtatc ctgatgctgg tctctatttt cttatttgtt aaaaatgaac
     6301 acgatattgt tgtctataca cttgtgatga gtttatcgac gctgattaac tacctgatta
     6361 gttatttttg gattaaaaga gacatcaaac ttgttaagat tcacctaagt gattttaaac
     6421 cactctttct ccctctgaca gccatgttag tctttgccaa tgccaatatg ctcttcactt
     6481 ttttagatcg cctcttcctc gttaaaacag ggattgatgt caacgttagt tactatacca
     6541 tagctcagcg aattgtgacc gttatagctg gggttgtaac aggtgcaatt ggagtgagtg
     6601 tgcctcgtct cagttactat ctggggaaag gagacaaaga agcctatgtt tctctggtta
     6661 atagaggtag tcgaatcttt aacttcttta tcattccact gagttttgga ctcatggttt
     6721 taggaccaaa tgccatccta ctttacggta gtgaaaaata tatcggaggc ggcatcttga
     6781 cctctctctt cgcttttcgt acgattatcc tggccttaga taccattctt ggttcccaaa
     6841 ttctctttac caatggctat gaaaaacgta tcacagtcta tacagtcttt gctgggctac
     6901 tcaatttggg cttgaatagt ctcctctttt tcaaccatat cgtggttcct gaatactact
     6961 tactgacaac tatgttatca gagacttctc tacttgtttt ctatattatt ttcatccata
     7021 gaaaacaact catccacttg ggacatatct ttagctatac tgttcgatac tctctctttt
     7081 cactttcctt tgtagcaatt tatttcctga ttaatttcgt gtatcctgtg gatatggtca
     7141 ttaatttgcc atttttaatt aatactggtt tgattgtctt gctatcagct atctcttata
     7201 ttagtctact tgtcttcaca aaagatagca ttttctatga atttttaaac catgtcctag
     7261 ccttaaaaaa taaattcaaa aaatcatagg agtttaaaat gaaacaacta accattgaag
     7321 atgccaaaca aattgaatta gaaattttgg attatattga tactctctgt aaaaagcaca
     7381 atatcaacta tattattaac tacggtactc tgattggggc ggttcgacat gagggcttta
     7441 tcccttggga cgacgatatt gatttatcca tgcctagaga agactaccaa cgatttatta
     7501 acatttttca aaaggaaaaa agcaagtata agctcctatc cttagaaact gataagaact
     7561 actttaacaa ctttatcaag ataaccgaca gtacgactaa aattattgat actcgaaata
     7621 caaaaaccta tgagtctggt atctttatcg atattttccc tatagatcgc tttgatgatc
     7681 ctaaggtcat tgatacttgt tataaactgg aaagcttcaa actgctgtct ttcagtaaac
     7741 ataaaaatat tgtctataag gatagccttt taaaagattg gatacgaaca gccttttggt
     7801 tgctccttcg accagtttct cctcgttatt ttgcaaataa aatcgagaaa gaaattcaaa
     7861 aatatagtcg tgaaaatggg cagtatatgg cttttatccc ttcaaaattt aaggaaaagg
     7921 aagtcttccc aagtggtacc tttgataaaa caatcgattt accctttgag aatttaagcc
     7981 ttcctgcacc tgaaaaattt gatactattt tgacacaatt ttatggagat tatatgaccc
     8041 taccaccaga agaaaaacgc ttctacagtc atgaatttca cgcttataaa ttggaggatt
     8101 aggatgcaat atttagaaaa aaaagaaatt aaagaaattc aactagccct gctggactat
     8161 attgatgaga cttgtaagaa acatgatatt ccttattttc tcagttatgg aaccatgctt
     8221 ggagccatcc gccacaaagg tatgattcct tgggatgatg atattgatat ttccctttat
     8281 cgtgaggatt atgagcgttt actgaagatt attgaagaag aaaatcaccc tcgctacaag
     8341 gttctttcct acgatacatc ttcttggtac ttccataatt tcgcatcgat tttggacact
     8401 tctactgtta tagaagacca tgttaagtac aagcgtcatg ataccagcct tttcatcgat
     8461 gtcttcccaa ttgatcgatt tacagacttg agcattgtcg acaagagcta taagtatgtg
     8521 gctcttcgtc aactagctta tatcaaaaaa tcacgagcag ttcacggtga tagcaaacta
     8581 aaagattttc ttagattatg tagctggtac gctctccgat ttgtcaatcc tcgctacttt
     8641 tacaagaaaa ttgatcaact agtcaaaaat gctgtaacca acattcctca atatgaagga
     8701 ggagttggga tcggtaagga agggatgaaa gaaatcttcc cagttgatac ctttaaagaa
     8761 ctgattttaa ctgagtttga gggccgtatg ttgcctgttc ccaaaaaata tgaccaattt
     8821 ttaacccaga tgtatggcga ttatatgaca ccaccatcaa aagaaatgca agagtggtat
     8881 agtcatagca ttaaagctta tcgcaaaaac tgattgaggg ggattataca aactactaag
     8941 atagaggtta ttcaaaaaca taattttagt agaaaatgaa atacatattc ccacaataaa
     9001 acgcatcata tcaaggtttt tgaaaaacct tgatatgatg cgttttataa ttttaaagac
     9061 ttttttctat agtagattga aataagatgc gaacaaatca attagaaaat tcaaattaat
     9121 ttatagaaat attttagtat tcctgtgtac tgttctaaat tcagtctgct atatcttatt
     9181 tttctattta aatcgcttct gtaacaaagc tacgactttc aagtacctta agcatggcat
     9241 tagctgtatc tagcgctgtg aagaggggca ccccgtgttc aatggctgaa cgacgaattt
     9301 gctcaccatc ttcgtcagca gttcgttttg ttcctactgt gttaatgata gcttgaattc
     9361 ttcctttgcg tacaaaactt gggatatcct tatcgtcatc accaatctta ccaacaggtt
     9421 gggcttgcaa gccatgacta gcaaagaagg ctgctgtccc ttctgtcgca aggattccat
     9481 aaccaatgtt ttggaaacga cgagccaagt tcaaggcttc ttctttggca tcatcagcga
     9541 tggtaaagac gacattacca aaagttggca agtgtagata agaagcttca aaggctttat
     9601 agagagcttt ttccaaagta gcatcagaac ccataacttc acctgttgac ttcatttcag
     9661 gaccgagcaa gctgtctacc ttagctagtt tggtaaagga gaagacaggt gccttgatat
     9721 gaacacgggt gctttcaggg taaagtccat tttggtagcc aagttctgat aaactttgac
     9781 caagaatgag cttggtcgct acttgagcca taggaatatt ggttacctta gataggaatg
     9841 gaacagtacg gctggcacgt ggattgacct caataacgta gactttttca tccttgataa
     9901 caaactggat gttcatcatt ccaaggcagt gaagaccgat tgctaagcgt ttggtgtagt
     9961 ctgcgatggt ctcctgaacc ttttgcgaca aggtttgtgg tgggtaaaca gccattgagt
    10021 cacctgagtg gacaccagca cgttcgatat gctccatgat accaggaatg agcacatctt
    10081 taccatctga aatggcatca acttcgcact cttgcccaac gatataagag tcgacaagaa
    10141 ctgggtgatc tggactagcc ttaacagcag ttcgcatgta agaacgaagg tcttcttcgt
    10201 tttcaacgat ttccatggca cgtccaccaa gtacataaga tgggcggaca agaactggga
    10261 agccaatctt acgagctgca agagctgctt cttcttcatt ggtagccgtt tgtcctggtg
    10321 gctgtggaat atccaattct ttgagagctt gctcgaagag gtcacggtct tcggcacggt
    10381 ctaggtcagc aacctgtgta ccaaggatgg tcacacctgc ttttgccaat ggctccgcaa
    10441 ggttgatggc tgtttgacca ccgaactgaa cgataactcc ctttggttgt tccaagtcaa
    10501 tgacgttcat aacatcttcg aatgtcaatg gctcaaagta aagcttatct gatacagaga
    10561 agtctgttga aacggtctct gggtttgagt tcatgatgat agcttcataa ccagctgcct
    10621 ggatagcctt aacagagtga acggttgcgt agtcaaactc aaccccttga ccgatacgga
    10681 ttggacctga acctaggaca agtacagatt ctttatcaga tctgatagat tcattttccc
    10741 aaccataggt tgaatagaaa tatggcgttt cggagtcgaa ctctgccgca caagtgtcta
    10801 ccatcttata aactggaaca atcttgtttt ccaagcgaag ttggcgaact ttatcatcag
    10861 tcgttcccca gagttcagca atcttacggt ctgaaaaacc attaagtttg gctgttttca
    10921 aaacttctag atcttgtgga tgagcaccca attcttgctc aatttcaaag atatgcaaga
    10981 gtttatcaag atagaagata tcaatttttg taagctctgc aatttcttca ggtgtgtagc
    11041 cacgacgaat tgcttctgat acgtagaaga gacggtcatc ttgggctttg acaacctttt
    11101 caatcaaggc atcatcagaa actgctgcaa gttcaggtat ttcattgtgg tgcaccccaa
    11161 tttcaaggga gcggcaggcc ttgagaagag attcctcgat gttacgaccg attgccatga
    11221 cttctccagt cgccttcatt tgtgtaccga gacggcgttc acccttttca aacttgtcaa
    11281 atgggaaacg tggaatctta gcaactacgt agtcaagggc tggttcaaac atggcatagg
    11341 ttgaacctgt aactgggttt ataacctcat ccaaggtcaa acctactgca atcttggcag
    11401 ccaacttagc aatcggatat cctgtcgctt tagaagcaag ggctgacgaa cgtgatacac
    11461 gagggtttac ttcgataaca taatacttga agctgttagg atcaagagct agctgaacat
    11521 tacatccacc ttcaatcttg agggcacgaa taatgctcaa gctcgcatca cgaagcattt
    11581 ggttttcata gtctgacatg gtttgcgcag gggcaaatac aatggaatcc cccgtgtgaa
    11641 tcccaactgg gtcaaagttt tccatgttac aaacaaccaa ggcattgtca gctgagtcac
    11701 gcatcacttc gtattcaatt tccttgaaac cagcaatcga acgctcaatc aaacattggg
    11761 taacaggtga caatttcaaa ccattttcag tgatttcacg caattctttc tcgttggcac
    11821 acataccacc accagtacca ccaagggtaa aggctggacg aacgatgact gggtagccaa
    11881 ttgtcgctgc aaaggcaact gcttcttcta ctgtgttaac aatttcagat tctggaatgg
    11941 gttgctcaag ctcttccatc aattgtttaa agaggtcacg gtcctccgct tggtcaatgg
    12001 cagacaattt agtacccaga agttcaacgc taagctcatc taagatacca tttttagaca
    12061 attccatggc catgttgaga cctgtctgac caccgagtgt tggtagcaag gcatctggac
    12121 gttccttacg aagaatacgt gtcacaaact caagtgtaat cggttcaatg taaaccttgt
    12181 cagcaatttc cttgtccgtc atgatggttg caggatttga gttaaccaaa acaacctcat
    12241 aaccttcctc tttcaacgac aagcaagcct gggtcccagc atagtcaaac tcagcagcct
    12301 gaccaataat aatcggacca gaaccaatca ccataatttt ttgaatatca gtacgtttag
    12361 gcatatataa gatattaagg gcgtcaagcg gacaaagcta aaataggagt tatgacgaag
    12421 aactgtcagt tctaggaata actatctttt tagcaccgtc cgtagcccgt attcagttca
    12481 gcaaatacgg agcacccttc tcctttctat tcgtcgcctc tcagggcgac attaaataag
    12541 atacaaagga cgaatagaaa gcgattgaat tttaagaaat caaggaagga ttgacaatcc
    12601 aagttggttt ctctaaattc tgagctttcc gtccgtgttc agttacataa attctccgac
    12661 gagcttttac tcgttcttag tttgattgtt taaaaacttc catcatctcg ataaactcgt
    12721 caaataggta gctagcgtcg tgtggcccag gagctgcatc tgggtggtat tgaacagaga
    12781 aagcaggttg gtatctgtgg cgcacacctt ccactgactt gtcattgatt tcttcgtggg
    12841 taataatcaa gtgctctggc aaatcctcgc ggctgactgc ataaccatgg ttctggctgg
    12901 tgaagtctac tcgtcctgtt gcgatttcac gtaccgcatg gttgaatcca cggtggccaa
    12961 acttcatctt ataggtctta gccccgtttg ccatagcaaa gagttgatgt cccatacaga
    13021 taccaaagat tggaattttt ccttgtacac cgcgaatcat atccagtgcc tgtggaacat
    13081 cttctgggtt acctggaccg tttgacaaca tcactccgtc aggattgaga tggagaattt
    13141 cttcagccgt tgtcgaataa ggaacaaccg tcacattaca gttgcgctta gaaagttcac
    13201 gtaggattga gtgcttgaga ccaaagtcta ctaacaccac gctcaaacca actcctggag
    13261 ctggatagga agttttagta gaaacctgct taatattatc tgtcggcaat actgttgctt
    13321 ggagctggtc agtcacatgg tccatactat ctccaacatg agtcaaggtt gctcgcatag
    13381 taccatgctt acgaataatc ttggtaagtg cacgcgtatc aatccctgaa ataccaggaa
    13441 ttttcttggc tttcaaaaat tcatccaagg tcatttggtt gcgccagttg cttgctctac
    13501 gcgctttttc gaaaacaaca actcccttac aagttggaat aatagattcg taatcatcac
    13561 ggttaattcc atagtttccg accaaaggat aagtaaaggt caagatttgt ccattataag
    13621 actggtctgt aatggattct tggtagccgg tcatccctgt attaaagacg atttcgcctg
    13681 ttacatcaat atctgctccg aaggccttgc cttcaaaaac tgtgccatct tctaatacta
    13741 gaattctttt tgtcatattt tcacctctcg tggacgctca ctggcgtctt ttaacgtctt
    13801 gtgttttagt tggcgtttct actcgctagt acggattcta agattgccat tcgaacaaag
    13861 acaccattgg tcatttgttg gacaatccgt gattttggtg cttcaaccaa gtggtctgct
    13921 atttctacat cacgattgat tggagctggg tgcatgagga ttgctgtttc tttcaaacga
    13981 tcgtaacgtt cttgagtcaa gccatgttgg gcatggtagt cttcttttga aaatacagct
    14041 ccactatcat ggcgttcgtg ttgcacacgg agaaacatca tgacatcaac ctgatcaatg
    14101 atttcatcaa tggttacaaa ctgtccatag tctgcaaact cttgacttct ccattcctca
    14161 ggtccagcga aaaagagttc agatcccaag cgtttcaaaa tctgcatatt ggatttggca
    14221 acgcgtgagt ggtccaagtc acctgcaata gcaactttaa gaccctcaaa gtggccaaat
    14281 tcctcataaa tggtcatcaa atcaagcaag ctctggctag ggtgttggcc cgaaccatct
    14341 ccaccattga tgatggaagt cgtaatcgtt ggactagcaa tcaattctct atagtagtcg
    14401 acctctggat ggcgaatcac acagacatcc actcctaaag cagacagagt caaaatggtg
    14461 tcataaagtg tctcaccctt attaaccgaa ctagtcttca catcaaagtc aagtcgttcc
    14521 aatccaagtt taatctctgc gacttcaaag gacttatgtg tccgtgtaga atcctcaaag
    14581 aagagattgg aaacaatcgg atggtcttca tagggaagct gggctccatt tttaaactca
    14641 attcctcgct tgatcaattt cattacttga tcgacagtga ggtcttccat ggacaccaca
    14701 tggttcaatg cttgttgatt ttctgacatg gctactcctt taactttcta agcttcttca
    14761 gtaatcagaa ctctgtcttg gtcatcaagt tctgtcatct ctacgatgat ttcttcagaa
    14821 cgactggttg ggatattttt tccaacgtaa tctggacgga ttggcaattc tctatgtcca
    14881 cgatcgacta gaactgctaa actcacacgc gcaggacgac catgaccgac aatattatca
    14941 atagcagcac ggatggtacg acctgtatag agcacatcat ccaccaagat aacttcgcgg
    15001 tctgtcacat cgacagaaac caaagaagta tcttctccac ttttaacatc atcacggaaa
    15061 ggtttagtat ccaattccac aacaggaact gaaagatttt ctaactgctt caaacgttct
    15121 tggattcggt gggcaataaa gacaccacga gttttaatac cagccaagac aatcttattc
    15181 aaatctttgt tgcgttcgat aatctcataa gtaatacgcg taatcgctcg tttgacggtc
    15241 aattcgtcta caacttcttt tgttttcatg acaaacctcc aaaaagaaaa gtctccttaa
    15301 acaaggagac ttgaaattta tagccaagcg agccctactg cacacagtat agacttcacc
    15361 cttctacttt atcgcgctcc ttgcctgcct cacgggacag gtttaaagga atatttagtt
    15421 atcatttact atagcacaaa gcatgcttaa aatcaagcaa aaagtttcaa tgtagcatct
    15481 tacaaattgc taaaatcata taattgtggg tactggtcac actctggatt ttttggatgg
    15541 caaatggctc ttccaaaata aatcatggcc tgatgggcag ctaaccactg ctcaggcggc
    15601 aagatatcca tgacccgctt ttccacctca agtggcgtcg ctgatttttt gacaatatcg
    15661 tggtgtttgc aaatacgctc cacatgagta tccactgcaa aggctggaat cccaaatcct
    15721 acactcatga caacattggc tgtcttgcga ccaacacctg ccaaactctc caattcttca
    15781 cgtgtctgag ggacttgacc atcaaaatcg tctagtaact gttgggcaca ttttttaagg
    15841 aatttagctt tattccgata caatcccaag cgagaaatat gtgaagcaat ctcactctct
    15901 gtcgctacag acatagcttg gggtgttgga aaggcaacaa agagacctgg tgtggcctta
    15961 tttaccgctg catctgtcgt ctgggctgat aacatgaccg caaccaggag ttcaaaatga
    16021 ttggtaaaat caagactagg cttggcatct gggaagaggg caatgatttc ttctagcacc
    16081 tttcgtgctc gtttttttga caagaccatt attcatctcc gtcaaatagt ccttgtaagc
    16141 cagcaaaagg actgttttct tctttcttta ctgcttgttg agcttggtat tcttcctctg
    16201 tcatgatttg ccagtcattt cctgagacaa atccttgacc agcttcttct tcagccgtca
    16261 agaccttgat aggaatgttt agcaggatat tgtctgatac actctcagca aggtcaagct
    16321 ccccattttc gatgggcaag accaagtcat catctaaaac ttcttgatct agctggttag
    16381 ttgcgccttc catgaaaact tccgtgactg gataagattc aactaactca actggctcca
    16441 tactgcgact cgaagcaaga acaatggtat aagatagttg ataatctaag aaatacatac
    16501 ggtcttcata ttgtactttc ccaactgcaa ggatatcttt tacatctaaa atttcttgat
    16561 tacgtgcacg caggtcatca actaaatcta acgtttgttc aaagttcaaa ccttcagact
    16621 gcttacgaat ttcttgaata tttaatttca tacttcctcc ataaagattt actctcttga
    16681 ttataccatg aaaaggctac aaatcagcac accaaacttt gtaattaaaa ttcgaaattt
    16741 taacatattc actatgacag ttttattttt tagtgctata ctatagggaa agagtacatc
    16801 agatcaagga ggatgctcac acggaagaca agaaactcat tcaactccta tccaagttaa
    16861 ataaaagcta ccaaaactgt aaacagggta cggcagatga tattcgacta caagagctgc
    16921 taaacactac tatgcaagaa ctcaaaaaac ggaaaagttg aacaacagta tcttaattga
    16981 tcttgagaaa ttttaccaac ccaccagtcc tatgattgga ctgggtagcc taaaactaaa
    17041 caatcaagaa cgcactgctt ggcgaaacta tgataaaatc cattacgagc atgtcaaaca
    17101 cgtactaagt ctctatagac ctgtttttgg attttagagc atagaatttc cagttttctg
    17161 ttgacaaaat ttccttaaaa gtatagtata aagatactaa tactaggagg taagggagac
    17221 atgaacaact aagtctatca aataaagaac ctttatttag tagatcttgt ttttgtctct
    17281 ttttgtgtgc tcttttatgc cctttttctg gcatgttaat agagtttttt tgacatagac
    17341 tttgggctct actaggtaaa gtagagcttt ttgttatgca ctatgaacat tctagaaagg
    17401 gcaatagtat gataaaaatc aatcacctga ccatcacaca aaacaaagat ttacgagacc
    17461 ttgtctctga cctaagcatg accatacaag acggggaaaa ggtagctatt attggcgaag
    17521 aaggaaatgg taaatcaacc ttacttaaaa ctttaatggg ggaagctttg tctgatttca
    17581 ctatcaaggg aaacatccaa tctgactatc agtcactggc ctacattcct caaaaacttc
    17641 ccgaggagct gaaaaagaaa actttacacg actacttctt tttagattct attgatttag
    17701 actacagtat cctctatcgt ttggcggagg aattgcattt tgatagcaat cgtttcgcaa
    17761 gtgaccaaga gattggcaat ctatcagggg gagaagcttt gaaaattcag cttatccatg
    17821 agttagccaa accctttgag attctatttt tagatgaacc ttcaaatgac ctagaccttg
    17881 agacagttga ttggctaaaa ggccagattc aaaagaccag gcaaaccgtt attttcattt
    17941 cccatgatga agactttctt tctgaaacgg cagacactat tgttcacttg cgactggtca
    18001 aacaccgtaa agaagcggaa acgctagtag agcatttaga ctatgatagc tatagtgagc
    18061 agagaaaggc taattttgcc aaacaaagtc agcaagctgc taacaaccaa agagcctacg
    18121 ataaaaccat ggaaaaacat cggagagtta agcaaaatgt agaaactgcg cttcgagcta
    18181 ccaaagatag tactgccggt cgcctattgg ctaaaaagat gaaaactgtc ctctcacaag
    18241 aaaaacgcta cgaaaaggca gctcagtcca tgactcaaaa accacttgaa gaggaacaaa
    18301 tccaactttt cttttcagac atccaaccat taccagcttc taaagtctta gtccaactgg
    18361 aaaaagaaaa tttgtccatt gacgaccgag ttttggttca aaaactacaa ctaactgtcc
    18421 gtgggcaaga aaaaatcggt attatcgggc caaatggtgt tgggaaatca actctgttag
    18481 ccaaattaaa gcaacttctg aatgataaaa gagagatttc ccttggtttt atgccacaag
    18541 attaccacaa aaaactacaa ttggatttat caccaatagc ttatatcagc aaaactgggg
    18601 aaaaagagga acttcagaaa atccactctc acctagccag tctcaatttc agttatccag
    18661 aaatgcagca tcaaattcgc tccttatctg gcggacaaca gggaaaactc ctgcttttgg
    18721 atctagtcct gcgcaaacca aactttctcc tgctggatga acccacacga aacttttctc
    18781 ccacttctca accccaaatc agaaaactct ttgcaaccta tccaggcggt ctcatcactg
    18841 tttcgcatga ccgtcgtttc ttaaaagaag tctgctcgat catctatcgc atgacagaac
    18901 acggtttgga gttagttaat ttagaagatt tataaatttg caacatagca aaaatccaga
    18961 gacgacctct ggattctttt acatctgttt taaacgttca atccgttctg agataggtgg
    19021 gtgggtataa aagagttttt ggaacccccc acctttcttg ggatcattga tataaagagc
    19081 actgctagca tcatcgacgt ggcgactcat cggtttgcta ttgtccaact tatctagggc
    19141 attaatcatt ccctggggat tgcgagtcag ctcaacacta gatgcatctg ccagaaattc
    19201 cctctgacga gaaatagcga gctgaaccaa ggttgcagcg agaggtgcca gtacaatagc
    19261 tagtagggaa accactagca taatgatttc aagaccattt ccatctcggt catcatcact
    19321 tcgtctgcga cctgctccac cccaccacat catacgacct gccataccag aaagcatggt
    19381 gatagcacta gcaagggcaa ctgcaatagt cgaaatacgg atatcataat tacgaatatg
    19441 actgacttca tgtcccataa cagcttctag ttcttcacga ttcatgatag ctagtagacc
    19501 tgaagtcgca gcaacagccg cattttgagg attagaacct gtcgcaaagg catttaaggc
    19561 tggatcatca atgatgaaaa cacggggcat aggaatctga gcgaccagag ccatatcttc
    19621 cactacatgg tagaggtctg gtgccgtttg ctcatccacc tcacgcgctc cattcatgga
    19681 catgacaatc tctgtcgatt gaaaaatcat agacaaagcg tagataaagc cgataatcag
    19741 tgcgataacc aaaccaccaa gtccagatct tataaagaga taaccaaccg cataaccaac
    19801 aagagctaag agtaggaaaa ataccagcaa caaaatccag gtttttcgtt tattgcttgc
    19861 aatttgatca aacaacatct tagtcaccta aaccgctaaa atcaacttta ggaaccgact
    19921 tttcctcttc aggtgtttga aggaaatctg ccgctttaaa tccaaacatt ccagcgataa
    19981 tattgctcgg gaaagtttct aattttacat tgtagttgct gacaacactg ttatagagtt
    20041 gacgagagta agaaatttta ttttctgtgt ttgtcaactc ctcttgcaat ttaacaaagt
    20101 tagcactagc tttcaaatct ggatagcttt ctgcaactgc aaaaatacct gaaacctgac
    20161 gagtgagggc atcactggct ttcatagctt ctgctggtga agtcgctgcc gccacttggt
    20221 tacgtagttc tgccaccttt tcaagggtag aaccttcata tttggcataa ccttttacag
    20281 tctcaatcaa gttcggcaag aggtcatttc gacgtttcaa ctgaacatca atctgactcc
    20341 aagcctcctt ggtttgcata cgatttttaa ccaaaccgtt atagctaaca atcacaaaaa
    20401 taacaataag agcgataact ccaagaataa tccaagtcat aatataagtc ctttctgctt
    20461 ttagattagt accagtatat caaattttct atgattgtgg taaaataaga tgatactaaa
    20521 gaaggaaata actatgaaac cagaaacatt ttacaacttg cttgccgagc agaatcttcc
    20581 actttcgaac cagcaaaaag aacaatttga acgttatttt gagctcttgg tcgagtggaa
    20641 tgagaagatt aatttgacgg cgattacgga caaggaagaa gtttatctca aacattttta
    20701 cgattcgatt gcacccattc ttcaaggttt gattcccaat gaaactatca aacttcttga
    20761 tatcggggct ggggcaggat ttcctagtct accaatgaaa attctctatc cggagttaga
    20821 tgtgaccatt attgattcac tcaataagcg catcaacttc ctacaactct tggctcaaga
    20881 actggatttg aacggagttc atttctacca cggacgtgcc gaagattttg cccaagacaa
    20941 gaacttccgt gctcaatatg attttgtaac agctcgtgcg gttgcccgta tgcaggtcct
    21001 atctgaattg actattccct accttaaggt tggtggcaaa ctattggcac tcaaggccag
    21061 caatgcgcct gaggaattat tagaagctaa gaatgccctc aatctccttt ttagtaaggt
    21121 cgaagacaat ctcagctacg ccctaccgaa tagagatccg cgctatatca cagtggtaga
    21181 aaagaaaaaa gaaacaccaa ataaatatcc acgtaaggct ggtatgccaa ataaacgccc
    21241 actttaaatt ttttagtaaa caaatgttta caaaatcagc ctcgctcttt tatttctagg
    21301 ctcgggaaaa aatgatttac aaaatcattt ttttctgcta tactatccta agcaaaggtt
    21361 tttaatgtca tcccgtgagg tgacgaagac gcaaaaatat ttgaaactct ttaaagtcta
    21421 gattttagag aagtcttact ctgagggcct attgctgtaa aataatgggc tcttttctga
    21481 tgcccaaaag tgaggtttat atgaaacaag aatcaactgt tgatttgtta ctagacgttg
    21541 accaacgtcc ttcggatgga aaaggaattc tccttagctt ccaacacgtt ttcgccatgt
    21601 ttggtgcgac catcttggta ccattgattt tgggaatgcc tgtatctgtt gccctttttg
    21661 cttcaggtgt tggaacactc atctacatga ttgctactgg ttttaaagtt ccagtttatc
    21721 taggttcttc atttgccttt atcacagcta tgtcactggc tatgaaagaa atgggggggg
    21781 atgtatctgc tgcccaaaca ggggttatct tgactggttt ggtctatgtc cttgttgcta
    21841 ccagcatccg atttgtagga acaaaatgga ttgataaact cttgccacca atcattatcg
    21901 gtcctatgat catcgttatc ggtcttggac ttgcaggttc agctgttacc aatgcaggtc
    21961 ttgtagcaga cggaaattgg aaaaatgctc tggtagccgt tgttactttc ctaattgctg
    22021 cctttatcaa tacaaaagga aaaggcttcc tacgaatcat tccattcctc tttgccatta
    22081 tcggtggtta ccttttcgca ctaactcttg gcttggttga ctttacacca gttcttaaag
    22141 ccaactggtt cgaaattcct ggtttctact tgccatttag cacaggtggt gcctttaaag
    22201 agtacaatct ttactttggt ccagaagcca tcgctatctt gccaatcgct atcgtaacaa
    22261 tttctgaaca tatcggagac catactgttt tgggtcaaat ctgtggtcgt caattcttaa
    22321 aagaaccagg tcttcaccgt actcttcttg gtgacggtat cgcaacttct gtttctgcct
    22381 tccttggtgg accagccaat acaacttacg gagaaaatac aggggttatc ggtatgactc
    22441 gtatcgcttc tgtctcagtt atccgtaacg ctgccttcat cgcgattgcc ctcagcttcc
    22501 ttggtaaatt cactgccttg atttcaacta ttccaaacgc tgtacttggt ggtatgtcaa
    22561 tccttctcta tggggttatc gccagcaatg gtttgaaagt cttgattaaa gaacgtgttg
    22621 atttcgctca aatgcgaaac ctcatcatcg caagtgctat gttggttctt ggacttggag
    22681 gagctatcct taaacttggt ccagttacac tttcaggtac tgccctttca gccatgacag
    22741 gaatcatctt gaacttgatc ttgccatacg aaaataaaga ctaagagtct aaatacacct
    22801 aatccactca gacagctgag tggatttttc gcataccata ataaaagtgt cttaacaaaa
    22861 ttattaaaat caaaaaacgt ataatatcag atattctaaa accttgatac tatacgtttt
    22921 atcatagaaa tttttacttt attttctcat caaatgagat ttgcatcaat ctcttgtctt
    22981 acttgcgttt cttcttcgct ttcttcattt tgttagccat acgtttcatg gactgtttca
    23041 tggcaaattc accaatttta cctttcaaac cgccaccaaa catctggctc atatctggca
    23101 ttcctgctcc tccgagagct gataagtcag gcataccgcc ttgtcccatc attccttcaa
    23161 gggcagacat atccattcct cccatatttg gcatattttt aggaaggtta tttggattaa
    23221 tccccatttg cttcatcatt ttattcatat ccccagacat aacaccctgc atgagctgtt
    23281 tagcctggtt aaagtccttg atgaatttat tgacttcgac gaatgtattt ccagaaccag
    23341 cagcaatacg acggcgacgg cttggattta acaaatttgg gttttcacgc tcttcaggtg
    23401 tcatcgaaga cacaatggca cgtttacgag caatctggcg ttcatccacc ttcatgtttt
    23461 gaagggctgg attgttggcc atacctggaa tcatcttgag caagtcttcc atcggcccca
    23521 tattttgcac ctgatctaat tgatcgatga aatcattaaa atcaaaggtg ttttcgcgca
    23581 tcttctcagc catttcaagg gctttttgtt catcgtattc ctgagaagct ttctcaatca
    23641 aagtgagcat atcccccata ccaaggatac ggctagacat gcggtctggg tggaaggttt
    23701 caatgtccgt aatcttttca cctgtaccag tgaacttgat tggttttcca gtaatgtgac
    23761 gaacagacag agcagcacca ccacgagtat cgccatcaat cttggtaagg atgaccccag
    23821 tcacttccaa ctgagcatta aactcacgcg caacattggc tgcttcctga ccaatcatag
    23881 catcaacgac aagcaagatt tcatttggtt gagccaatgc tttcacatca cgaagctcat
    23941 tcatgaggag ctcatcaatc tgcaaacgac ccgcagtatc aatcaagaca tagtcgttat
    24001 gattagtttg ggcttgctcc aaaccttgac gtacaatctc aacagctggt acttctgttc
    24061 caagtgcaaa gacaggcaca tcaatctgtt gtcccaaggt cttaagctgg tcaatggcag
    24121 ctggacgata aatatccgcc gcaatcatca aaggacgagc attttcttct ttcttgagtt
    24181 tgttggccaa tttaccagca aaggttgttt taccagcccc ttgtaaacca accatcatga
    24241 tgatggttgg aatcttaggt gacttgataa tttctgccgt atcagaacct aaaacggctg
    24301 tcagttcctc atcaacgatt ttaataatct gttgcgcagg attaagtgta tcaatgacct
    24361 catgcccgac tgcacgctca cgaactttct tgataaagtc ctttacaaca ggcaaggcaa
    24421 cgtcggcctc gagcaaggcc aagcgaattt ctttggttgc ctcttggaca tcagattcag
    24481 agatttttcc ttttttacgt agatttttaa agacgttctg caaacgttct gttaaacttt
    24541 caaatgccat ttttcttcct cttattctct attatcaatg cttgttaaaa tttctatctg
    24601 ctcctgcaga aagttatcct tgggatagcg ctccaaaatc tgatcaaaaa tctgactgcg
    24661 gacaatatag tccgagtaca tgtgcaattt catctcataa tcttccagaa tcttttctgt
    24721 tcgcttgata ttgtcataga cagcctgacg actgacaccg aactcctcgg caatttcagc
    24781 aaggctgtaa tcatcagcgt agtagagctc gatataattc atttgcttat ctgtcaaaag
    24841 cgccgcataa aattcaaaga gcgcattcat acgattggtt ttttcgattt ccataacttt
    24901 tattatacca aaaattagcc taatctacca cactaggaaa ccgatccaag aagatagata
    24961 gctaaatttg aaaaagacat gagcctagcc ccaagtaatt tccaattgat agctggcaaa
    25021 aggatgtccc tcttgatttt gtagttgata atctagttca atcttttgcc tatcaacttg
    25081 ataatggctc gtttggatga taaactcctg catgcccata ggtgtaggaa tataggctaa
    25141 actatcgcta ttctttagaa agcgcataat ggtcttggga ttagaaaatc ggctcatcac
    25201 aagttcttga ccatgaaatt taatcactac tttttccttt tcctcattat agaaaagcag
    25261 gtagctataa tctccttttt catgcacttc cacatcataa agctggtcaa tcacttccaa
    25321 ctgctcatca aactgaattg tatttcgcat ccgaatcttc acatcaggcc ctctttcttg
    25381 tctcttgtcc tactatttta ccaaaaagag caggattttg ctataatggt catatgaacg
    25441 aaaaagtatt ccgtgaccca gttcacaact acatccatgt cattaatcaa atcatctatg
    25501 acttgattaa tacaaaagaa tttcagcgtt tgcgccggat caaacaactg ggaacttcca
    25561 gttatacctt ccacggtgga gaacacagtc gcttctctca ctgtctagga gtctatgaaa
    25621 ttgcacgacg catcacagag attttcgaag aaaaatatcc tgaggaatgg aatcctgccg
    25681 agtctctctt gaccatgatc gctgctctcc tacatgacct tgggcatggc gcctactccc
    25741 atacttttga acatctcttt gatacagacc atgaagctat tactcaggag attattcaaa
    25801 gtcctgagac agagattcac caagtcttgc tacaagtagc gcccgatttt ccagagaaag
    25861 ttgccagtgt catagaccat acctatccta acaagcaggt cgtacaactc atttctagtc
    25921 agattgacgc agatcgcatg gactatctct tgcgtgactc ctattttaca ggagcatcct
    25981 atggggaatt tgacctgact cgaatcctcc gagtcattcg tcctatcgaa aatggtatcg
    26041 cctttcagcg caatggcatg cacgccatcg aagactatgt cctcagtcgc taccagatgt
    26101 atatgcaggt ctatttccac ccagcaacac gcgctatgga agttctccta cagaatcttc
    26161 tcaagcgcgc taaggaactc taccctaagg acaaagactt ctttgcacga acttccccac
    26221 acctcctgcc tttctttgaa aaaaatgtga ccttgtctga ctatctggct ctagatgatg
    26281 gtgtgatgaa tacctacttc cagctctgga tgaccagtcc tgacaaaatt ctcgcagatt
    26341 tatcgcaacg ctttgtcaac cgcaaggtct ttaaatccat taccttttca caagaagatc
    26401 aagaccaact cgctagcatg agaaaattgg ttgaggacat tggctttgat cccgactact
    26461 atactgccat tcataagaac tttgacctcc cttatgatat ctatcgtccc gaatctgaaa
    26521 atccacggac acagattgag attttacaaa agaatggaga actggccgaa ctctctagcc
    26581 tgtctcctat cgtccaatcc cttgctggta gtcgtcacgg agataatcgt ttctattttc
    26641 cgaaagaaat gttagatcaa aacagtatct ttgctagcat tacccagcaa tttttatact
    26701 tgattgagaa cgatcatttt accccaaata aaaactagaa gaggaaattt atgagtatta
    26761 aactaattgc cgttgatatc gacggaaccc ttgtcaacag ccaaaaggaa atcactcctg
    26821 aagtcttttc tgccatccaa gatgccaaag aagctggtgt caaagtcgtg attgcaactg
    26881 gccgccccat cgcaggtgtt gccaaacttc tagacgactt gcagttgaga gaccaaggtg
    26941 actatgtggt gaccttcaat ggtgcccttg tccaagaaac tgctactggc catgagatta
    27001 tcagcgaatc cttgacctat gaggattatc tggatatgga attcctcagt cgcaagctcg
    27061 gtgtccacat gcatgccatt accaaggacg gtatctatac tgcaaatcgc aatatcggaa
    27121 catacactgt acacgaatca accctcgtca gcatgcctat cttctaccgt acccctgaag
    27181 aaatggctgg caaagaaatt gttaaatgta tgtttatcga tgaaccagaa attctcgatg
    27241 ctgcgattga aaaaatacca gccgaatttt acgagcacta ctctatcaac aaatctgctc
    27301 ctttctacct cgaactcctt aaaaagaatg tagacaaggg ttcagctatt actcacttag
    27361 ctgaaaaact aggattaacc aaagatgaaa ccatggctat cggagacgaa gaaaatgacc
    27421 gtgccatgct ggaagtcgtt ggcaaccctg ttgtcatgga aaatggaaat ccagaaatca
    27481 aaaaaatcgc caaatacatc actaaatcta atgatgaatc tggcgttgcc catgccatcc
    27541 gtacatgggt actgtaaaag tatcattttt caataagaat tgattagcaa taaaatccaa
    27601 tgaatttttt tagcaaacta tttaatttaa aacaaaataa tcataataga gacacaaatt
    27661 ctgattgtaa caatttttac ctaaacaaat tagagtgcgg ccttactcct gggcaactca
    27721 tactcataga ttggactcaa aaaacaggga gaaattataa tttcccaaga tattttaaat
    27781 actctcttca aattgaccct gaatctacac acaatcaatt atacaaatta ggatacttca
    27841 ctaaaaataa gactttatca tatcttaaag tagtagaatt aaaaactata ttatctaaac
    27901 ataatttagc tacttctgga aaaaaagcag aattaattac aagaataatt aataatatca
    27961 acgttgacaa attagatatt ccgttcgaat ttaaactaac aaaagaagca caaaatctta
    28021 ttatcgaaca tagtgactat atcaaagcat actatgataa agacataagt atggaagatt
    28081 attgtaaaga aaaaaacaat atctctttta aagcaacttt tggtgatata aaatggagtc
    28141 tcttaaataa acaagctcat aggaatactg tatcaggaga ttttggatgc ttatctaaca
    28201 cacgaaaggc tcagggaaga catttggaac aagaaggtaa tattaaacat gctttaatat
    28261 attacataga atctttgata attactattt caggattaga aaacaatttt tcagccactg
    28321 attatccagt atattatccc gattcgatac ctgactactc actaaaacat attcaaacat
    28381 taatggaatc attatctgat gacgattatg attttgcttt tgatgaagca ttatttcgct
    28441 tctcaatttt gaatgcaaat cattttttat ctaaggaaga tattgactat ttaagagtta
    28501 atttacctcg ttccactgct gaagaaataa acaattactt aaagaaatat gaatgttata
    28561 gtcctttaaa taatttagaa cttgacgatt ttgaataaat tgactataca aacatttata
    28621 tactcgatat agtctcaatt ttatctgatg attgcccaaa tttttcaata ataaaacgca
    28681 taatattatg gagacaatcc cctatattat gcgttctttt aatatcaaag actttttgac
    28741 aaacttcttt gatatctaat tactgccccc tgcaggaatc gaacctgcaa ctactcctta
    28801 ggagggagtt gttatatcca ttgaactaag ggagctagat aaaaactctg ctgaaaagca
    28861 gagtttttta gtcgaattaa cgacggattt ctttgatacg agctgcttta ccttgaagag
    28921 cacgcaagta gtacaatttc gcacgacgta ctttaccgta acgaacaact tcgatttttt
    28981 caacacgtgg agtgtggatt gggaagatac gctcaacacc tacaccgtta gagattttac
    29041 gaactgtgta gttttctgag attccagcac ctttacgtgc gataacaaca ccttcaaaaa
    29101 tctggatacg ttcgcggtta ccttcgacaa ctttcgcgtg tacacgaaca gtatcaccag
    29161 gacggaatga tgggatatct gtacgaagtt gaccttcagt caagctttgg attaatggat
    29221 tcattttatt ctcctatctt tgtcaatctt gaggaatctt cctcagcgga taaactgtat
    29281 ttttgtgcgt ccattacaca caagatacag tttaccaaat ttctaaaaaa aagtaaagaa
    29341 atttatagca aaattcctaa aaaaatcgca accaaaccac ctatgtaagt caaagtcagg
    29401 taagaataaa agaccttctt atcacttagc agtctttgaa gttcgtcatt caaggtcgaa
    29461 aaagttgtta aaccgccaca aaatcctgtt gctagaatag catatacttc cttagactct
    29521 acatgattgt agaatactcc aattaaaaaa caacctaaaa gattagctat gagcgttccg
    29581 agtggcaatt tagaaacttg attatagcga gaaaagaaat accgtacgag tgctcccaag
    29641 ccacaggcga ttgcaagata gacgattacc atttcttcct ccccaaatag taagctaaaa
    29701 gcaggcctcc accgatactc aaaagcaaat acagtatcaa actaagataa cgccctgtat
    29761 caagcagctt cacagtatca agcattaggc tggaaaaagt tgttaaacct ccgcaaaaac
    29821 ccgtccccag tgctaaaatc aagcccttac tagtcccctt atagaccaga tagcccttga
    29881 caagataaat caagcagaaa attcccagat agttgacaaa gagagtgccc caaggaaagt
    29941 ctggactggc tggtaaccag gtggaaacta gatatcggac aagtccgccc aacatagcag
    30001 ctagaaaaat tcctagcgga taaaattgtt cttttttcat ttgatatttt gatcctgata
    30061 atcacgcgaa cgtttgagta tgtccgaaaa agtcgctaca atagtctcct gatagcgctt
    30121 gtcctctaca cgactcccaa ccttttcaaa aataacttct tctctcttag tatctaaaat
    30181 cggtttacct gaagctttct tataagcaac caccccctca actaaatgca ttcgttcttc
    30241 taacagtttg acaatttggt cgtcgatttg atcgatttct tgacgaataa tatctaaatc
    30301 catacagtct cctcctttat ttgaattatt gtatcaaaaa gccatcaatt aggctagtaa
    30361 aatcccaact ctcgataaga aaaatgcact gattgattac atcagcgcac ttttatgctt
    30421 atcctacttt agcaaccaat tcttctgcga attgttccaa gcgttcaata tcttcttcct
    30481 cggcagaaag atcaacttta acacactctg aacctttttc tgctcctgtt gacacaaaga
    30541 cacggtcaaa gtcatcaaca gccttacaga attcatcgta gaaggtatct cctgagccga
    30601 ccactccgta gattttgcca ttcaagttga gatctgctag gtcttcgtag aagtccatca
    30661 tctcatctgg caattcacca tcaccataag tataggtcgc aacgatagcg atgtctgctt
    30721 ccaagaagtc tgaagcgtca acagttgtac attcatcaac atcaacatcc aagcccaagt
    30781 cacgtaattt gtctgctaca atatctgcaa tttcttcggt attaccggtc atactggcaa
    30841 atacaatttt tgctaatgcc atatcgtcct cctcaattta tctttctcca ttatatcaca
    30901 tctttttcat tttaaaaata aaaattcttg tgctacaatg aaatgagaaa gaattgaggt
    30961 tatttatgga gatttgccaa caaattttag aaaaaattaa agaatacgac accattatca
    31021 ttcatcgtca tatgaaacca gaccctgatg ccttgggaag tcaggtggga ttgaaagcct
    31081 tgctggaaca tcatttccca gaaaaaacca tcaaagccgt cggttttgat gaaccaactc
    31141 ttacttggat ggctgagatg gatcttgttg aagatagggc ctaccaaggc gcacttgtca
    31201 tcgtctgtga tacagctaat actgctcgta tcgatgataa acgctatagt caaggtgatt
    31261 ttctcattaa gattgaccac catccaaatg atgatgtata cggtgacctg tcttgggtcg
    31321 atactagttc aagtagcgct agcgagatga ttaccctatt tgcccaaaca acccaactag
    31381 ccttggcaga tcgcgatgct gagttgctct ttgcaggaat tgtcggtgat acaggtcgct
    31441 tcctctaccc ttctaccact gcacggactc ttcgcctggc tgcttatttg agagaacata
    31501 actttgactt tgcggctctc actcgcaaaa tggacactat gagctacaaa attgctaaac
    31561 tgcaaggcta catctacgac catctggaag tggatgaaaa tggtgctgct cgcgttatcc
    31621 tgagtcaaga agtcttgaaa caatacaatg taaccgatgc tgaaactgca gccattgtaa
    31681 gtgcacctgg gcgtattgat agtgttagtc tctggggaat ttttgtggaa caggctgatg
    31741 gccactaccg cgttcgctta cgcagtaaaa tccatcctat caatgaaatt gccaaggaac
    31801 atgatggtgg aggccaccct ctagcaagtg gtgctaattc ctatagccta gaggaaaacg
    31861 aaatcatcta ccaaaagtta aaaaacttgc ttaaaaactg ataaaatact tgccaaactt
    31921 ttcagaatct gatagactag tatggtaaca atctatggct cgcaaagaga ccatggcaga
    31981 aaggaaatat tgcaaaatga aaaaagatat ccatccagaa tatcgcccag ttgtcttcat
    32041 ggacacaact actggttacc aattccttag cggttcaaca aaacgctcta acgaaacagt
    32101 tgagttcgaa ggcgagactt acccattgat ccgtgtggaa atttcatcag actcacaccc
    32161 attctacact ggacgtcaaa agttcactca agcagatgga cgcgtggatc gtttcaacaa
    32221 aaaatacggt ctcaaataat gataagagaa cagtttcggc tgttcctttt tgtttcttga
    32281 aatcaactgc tgttttcatg ttccagactc atctgtaggt tcggtttcca tgctactagg
    32341 caggaaggaa atagctgttt caacacgtcc ataatgagct atactattgt cacgaaccac
    32401 actttcattg atggtccaag tggaattcat tttcttaaaa gcttctcgga ctttttccaa
    32461 atctttggag gcaatggcct gctctaaggt ttcaaaacga ggacttagac ggtttaccaa
    32521 tttttccttt tccgcatcta ggtcaacagg attttgttct ttttcaaaag ctaatagagc
    32581 tgaggaaatt tcggtgagtt tggcttcagt aatatctcca gatagagcta acttttcctt
    32641 aacaatctta ccaacctcag aatccttatt ttctactctt tcgaagtctg atgccatctc
    32701 ttgaacaagt ttctgggcct cagactgatt gccatttttg accgctttag aagtatctgt
    32761 gatttttacg aaataagaac tcaaactttc ttgggcacct actggggaaa gaattaaaaa
    32821 tgacaaagct aaaacaagca accagctcct agctttccaa taatttctga ccaatgtagt
    32881 ctcctttctc cacaccacca aagcaagtaa aaagtccact acctatgtga gtgatgtatt
    32941 cattcatctt atcagtagca cctagattag tttgaacctt aacaaagtta tcaggatcct
    33001 tctggaaaga aatgaagagc aaacccgtat caaactgacc agtcttttca tcaatgccat
    33061 ctgagtaaga gtaagaacaa cgcaaaagtg gcttgtccac ttacttagcc aaacgaacat
    33121 gcgaatcatc tagcaaaaaa ctcaaattca cttcatcaaa ctcatttttt taccgaaagg
    33181 ggcactactt tccttgtaac gaccaaaggt attttcttgt tcttagagac cagtgcggtc
    33241 ccaggtctct aaaaacatct gaatccgacg aactgccata taagaaccat tttccatcca
    33301 gtccttacta tcagcccaga taacgcggtc aaagtcttgc tccttggttt gatttgctgt
    33361 tccatcctta aaaccaaaga ggttccgcgg agtctccatt cggtccccga tagctgcaaa
    33421 tccagactga ctccaacgaa ggggcaccgc atttctcccc ttacgtatga gattgcgaat
    33481 agcgtgaaag gcaatttgct catcatctgc acaagcatga atcacaatat ctccaccagt
    33541 atatttttca cgtaattgct ccttaggaaa tagaggtaaa tccctgaaca gtcgagggcg
    33601 cttgttttcc aagttcatct ttttcaagaa acttgcagat acaccaaaag tcagcgtcaa
    33661 acgatgagga ttgagcccaa ctgtctcacc agtatcgctc ggaggaaaga gagcattctg
    33721 tccatctttt ttaaccaatt ccccctcgac caacttggca ctataatccg tccaatcctt
    33781 gaatagctgg ataattttat ctctatccgt cgtatgcagg tccaagacaa caaaatagat
    33841 attcttttgc atgggcgtac tatttggtac atcaagcgaa ccttacgaaa acgtctacta
    33901 tatttaaagc gctttcttgt cttcttgaat taagatttta tttttagacg cgacaatggt
    33961 ttgagcgtct gctttcctag gatgttctgg acgtggcata atatttcgcc aaccatggtg
    34021 cttcaacagt tgatagaagg catcacgtgt gtaggaacga cctaactcct ttttataagc
    34081 ctgatataag gcatcaattg taacaaattc tcctgcctct gcagccttca aatggcgagc
    34141 aagaaaggct ttctcttgct caaccgtcat atatgcatgg ttacgaccac cacgtgtttc
    34201 ttgaaagaga gagtcgagtc cgaactcctc atattttttt acatttcgcc aaatcgttgt
    34261 ttgattacag tctaaaagct ctataatctc tttataagat ttgcccatca gacgaaatat
    34321 agtagattga aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg
    34381 actgtcctga tcgatttgcc ctgttcttgt ttcgttttac tatagaacga tttgaaggcg
    34441 tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggttt ggatttcttc
    34501 tttagttgat ttcatatcac tattatataa tactttttta ttttagtcta gtctaaatat
    34561 tgcttttctc caaaatggtc atagttttac tggcaaatct aacatatcac ggataaatta
    34621 acaagtgatt tctgaattgc taaacatttt cttttcttat agcatacttt aagattttgt
    34681 ctttgagaaa gatatttcca agaaaaacgt tcgttttttt atctattttc aaaaaaacca
    34741 aaaaactgaa ttgaaagaat ttttagaaaa tttctgtttt ttctttacag tgaaaaaaaa
    34801 ttctgctata atgtcttatg taataaaata tgacaataaa aggagaacga tatgacatct
    34861 gctaaagaat atatccaaag cgtgtttgaa actgtgaaag ctcgtaacgg gcacgaggct
    34921 gaattcctcc aagctgttga agaatttttc aacactttag aacctgtatt tgaaaaacac
    34981 cctgagtata tcgaagaaaa tatcttggca cgtattactg agcctgagcg cgtggtttct
    35041 ttccgtgttc cttgggttga ccgtgatgga aaaattcaag taaaccgtgg ttaccgtgtt
    35101 caattcaact cagctgttgg accatacaaa ggtggacttc gtttccaccc aactgtaaac
    35161 caagggatct tgaaattcct cggatttgaa caaatcttta aaaatgtctt gactggactt
    35221 cctatcggtg gaggtaaagg tggatcagac ttcgatccta aaggtaaaac agatgctgaa
    35281 gtgatgcgct tctgccaaag cttcatgact gaattgcaaa aacacatcgg accatcactt
    35341 gacgtacctg ctggtgatat cggtgttggt ggacgtgaaa ttggttacct ttacggtcaa
    35401 tacaaacgtc ttaaccaatt tgatgctggt gtcttgactg gtaaacctct tggatttggt
    35461 ggtagcttga ttcgtccaga agcaactggt tacggtttgg tttactatac tgaagaaatg
    35521 ctcaaagcta acggtaacag ctttgctggt aagaaagtcg ttatttcagg ttctggtaac
    35581 gttgctcaat atgctcttca aaaagcaact gaactcggtg caactgttat ttctgtttct
    35641 gactcaaatg gttatgtcat cgatgaaaat ggtatcgact tcgatctttt ggttgatgtt
    35701 aaagaaaaac gtcgtgctcg tttgactgag tatgcagctg aaaaagcaac tgcaacctac
    35761 cacgaaggta ctgtatggac ttacgctgga aactatgaca ttgctcttcc atgtgccact
    35821 caaaacgaaa tcaacggtga agcagctaaa cgtttggttg ctcaaggcat tatctgtgta
    35881 tctgaaggtg ccaacatgcc gagcgacctt gatgccatca aagtttacaa agaaaatggt
    35941 atcttatacg gacctgcaaa agctgccaac gctggtggtg tagccgtttc agctcttgaa
    36001 atgagccaaa acagtcttcg cctctcatgg actcgtgaag aagttgatga ccgtctcaaa
    36061 gacatcatga caaacatctt caacacagct aaaacgactt cagaaacata cggtcttgat
    36121 aaagactacc ttgcaggagc taacattgct gcctttgaaa atgtagcaaa cgctatgatt
    36181 gcccaaggta ttgtttaaga tttatttgct taatcctcaa tcactacgat tggggatttt
    36241 tagttgagtt agacagttgg gaaattctaa ttaaatgaaa taaaaactga acaaattgat
    36301 tgcggaattc aaaccaattt ctaacatatt tctagaaatt aatttgactt ttctaatcga
    36361 tttgttcata tcttatttca atttactata cttacttaac cctttttata ctcaatgaaa
    36421 atcaaagagc aaactaggaa gcgagtcgca ggctgtactt gagtacggca aggcaaagct
    36481 gacgtggttt gaagagattt tcaaagagta ttaaacaaaa agaaaaaacg ctactcctaa
    36541 gaatagcgat ttaatcatgt ttttaagcta ctactgtagt tgctctatta tttaagtgtt
    36601 atgaataact tcaatatctt taaagctttt tgttagattt ataatttcaa ctatagccat
    36661 ctctactcct tagtttacag caaaaaatta tgcttaattc ttattgtttt tgtaaacaat
    36721 cagcgaaccc aatactattc cattcaacaa tcctaaagaa ataccatatt caactggaaa
    36781 atctaaaaaa attgcaaaca ctattccaat catcacccct agtgaggctg ttgttaaaat
    36841 tacatattca ttttctttct tcattttctt tacacctcat ttcctttttg tatataagct
    36901 gtagtactct ccaccaagat ccattaagta cttatgattt cctgactcaa caatcttacc
    36961 acctttcatt acaacaataa tatccgcatc cttaatcgtt gacaatctat gagctacaat
    37021 tatttgagta cagccctgac tttttatata ctttgttatt ctttcctcat taatagtgtc
    37081 taaagcacta gttgcttcat ctaaaattac aatactagga ttatttatta atgcacgtgc
    37141 cagtgctatc cgttgtcttt gaccacctga aatatttgaa cccatctctg agatgatagt
    37201 attaaatttc atcggcatag ccatgatttc atcatagatt tgaactgctt tacaaacttc
    37261 ctctatcttt tgtgaagtaa cttcgtgctt taaagttatg ttatcaagaa tacttctgtt
    37321 caataaaaac gaatcctgtg gaactactcc taaattttga cttaatattt ttttatctat
    37381 ttgattaata tttacaccat caaataaaac ttttcctgta tcaatcttat ataatcctga
    37441 tggtattttt gataatgtac tttttcctga ccccggttga ccgactagtg caattctctg
    37501 tcctgactca atagtcaaat ttaaattttc tattacaaga gctgagtctt tggaataaga
    37561 gaaagatagg tccttaatat ctattctact tcaaacgttt ctaaactata ctccggaaaa
    37621 taatttaacc aataactatc tttcatcgta tcctccaacc agtactaaga gtctgggaca
    37681 atagtctctt atctccaaaa aagaagcgga tttgccgttg cttttttgca tggttgcgat
    37741 agtcttggta aaatagaatt gcccaataaa ccatttagaa gggctatccc atgcatattc
    37801 actataacac aaatcaaaca actttaccac tagaaatcag ttctttcttg ccgcaagacc
    37861 atctcgtctt tactattgaa aaagtggtga ataccgatga aaaggaggta aaccatctga
    37921 ttaaacccaa atcattcata cctctctcaa ctagatgtaa cttacaaaac ccctgacctc
    37981 atgagccact ttcttcctcc tcatgaggtc agttttactt tctgctgttc cagtatcgtt
    38041 tttcctcgct agatttcctc aaaagggcag actcctccct tggtgcgtca catgattttt
    38101 tcatctcgac tgttctttaa tgcatcatta acgacgcttt t
//
LOCUS       DAVBOM010000016        37881 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBOM010000016 DAVBOM010000000
VERSION     DAVBOM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.016"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..399
                     /locus_tag="VQ878_000864"
     CDS             <1..399
                     /locus_tag="VQ878_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3095222.1"
                     /translation="SEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQ
                     HDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAI
                     IDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(444..1085)
                     /gene="plsY"
                     /locus_tag="VQ878_000865"
     CDS             complement(444..1085)
                     /gene="plsY"
                     /locus_tag="VQ878_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET3095223.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1221..3164
                     /gene="parE"
                     /locus_tag="VQ878_000866"
     CDS             1221..3164
                     /gene="parE"
                     /locus_tag="VQ878_000866"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET3095224.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3584..6055
                     /gene="parC"
                     /locus_tag="VQ878_000867"
     CDS             3584..6055
                     /gene="parC"
                     /locus_tag="VQ878_000867"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET3095225.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6187..7209
                     /locus_tag="VQ878_000868"
     CDS             6187..7209
                     /locus_tag="VQ878_000868"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET3095226.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7265..7969
                     /locus_tag="VQ878_000869"
     CDS             7265..7969
                     /locus_tag="VQ878_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3095227.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNGTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8034..8723
                     /locus_tag="VQ878_000870"
     CDS             8034..8723
                     /locus_tag="VQ878_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET3095228.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8720..9643
                     /locus_tag="VQ878_000871"
     CDS             8720..9643
                     /locus_tag="VQ878_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET3095229.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9658..10302
                     /gene="pcp"
                     /locus_tag="VQ878_000872"
     CDS             9658..10302
                     /gene="pcp"
                     /locus_tag="VQ878_000872"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3095230.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10470..10700
                     /locus_tag="VQ878_000873"
     CDS             10470..10700
                     /locus_tag="VQ878_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET3095231.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIVELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10750..10830
                     /locus_tag="VQ878_000874"
     tRNA            10750..10830
                     /locus_tag="VQ878_000874"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10784..10786,aa:Tyr,seq:gta)
     gene            10840..10911
                     /locus_tag="VQ878_000875"
     tRNA            10840..10911
                     /locus_tag="VQ878_000875"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10872..10874,aa:Gln,seq:ttg)
     gene            11073..12275
                     /gene="rpsA"
                     /locus_tag="VQ878_000876"
     CDS             11073..12275
                     /gene="rpsA"
                     /locus_tag="VQ878_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET3095232.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12361..12858
                     /locus_tag="VQ878_000877"
     CDS             12361..12858
                     /locus_tag="VQ878_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET3095233.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12858..14513
                     /gene="dnaX"
                     /locus_tag="VQ878_000878"
     CDS             12858..14513
                     /gene="dnaX"
                     /locus_tag="VQ878_000878"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET3095234.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14541..14735
                     /locus_tag="VQ878_000879"
     CDS             14541..14735
                     /locus_tag="VQ878_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET3095235.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14885..15655
                     /gene="sufC"
                     /locus_tag="VQ878_000880"
     CDS             14885..15655
                     /gene="sufC"
                     /locus_tag="VQ878_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET3095236.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15683..16945
                     /gene="sufD"
                     /locus_tag="VQ878_000881"
     CDS             15683..16945
                     /gene="sufD"
                     /locus_tag="VQ878_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET3095237.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIAHSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16956..18182
                     /locus_tag="VQ878_000882"
     CDS             16956..18182
                     /locus_tag="VQ878_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3095238.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVSATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18169..18609
                     /locus_tag="VQ878_000883"
     CDS             18169..18609
                     /locus_tag="VQ878_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET3095239.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18663..20075
                     /gene="sufB"
                     /locus_tag="VQ878_000884"
     CDS             18663..20075
                     /gene="sufB"
                     /locus_tag="VQ878_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET3095240.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20274..21515)
                     /locus_tag="VQ878_000885"
     CDS             complement(20274..21515)
                     /locus_tag="VQ878_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET3095241.1"
                     /translation="MKKIFLTLLTVSLLGGVSTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21618..22727
                     /locus_tag="VQ878_000886"
     CDS             21618..22727
                     /locus_tag="VQ878_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3095242.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23373..23720
                     /gene="ssrA"
                     /locus_tag="VQ878_000887"
     tmRNA           23373..23720
                     /gene="ssrA"
                     /locus_tag="VQ878_000887"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23903..23990)
                     /locus_tag="VQ878_000888"
     tRNA            complement(23903..23990)
                     /locus_tag="VQ878_000888"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23954..23956),aa:Ser,seq:gga)
     gene            24152..24892
                     /locus_tag="VQ878_000889"
     CDS             24152..24892
                     /locus_tag="VQ878_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3095243.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24889..25800
                     /gene="pfkB"
                     /locus_tag="VQ878_000890"
     CDS             24889..25800
                     /gene="pfkB"
                     /locus_tag="VQ878_000890"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET3095244.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25797..27749
                     /locus_tag="VQ878_000891"
     CDS             25797..27749
                     /locus_tag="VQ878_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3095245.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27913..30138
                     /locus_tag="VQ878_000892"
     CDS             27913..30138
                     /locus_tag="VQ878_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3095246.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30291..30719)
                     /locus_tag="VQ878_000893"
     CDS             complement(30291..30719)
                     /locus_tag="VQ878_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095247.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            30857..31999
                     /locus_tag="VQ878_000894"
     CDS             30857..31999
                     /locus_tag="VQ878_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3095248.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            32008..33222
                     /gene="thiI"
                     /locus_tag="VQ878_000895"
     CDS             32008..33222
                     /gene="thiI"
                     /locus_tag="VQ878_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET3095249.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33357..34181
                     /locus_tag="VQ878_000896"
     CDS             33357..34181
                     /locus_tag="VQ878_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3095250.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            34194..35360
                     /locus_tag="VQ878_000897"
     CDS             34194..35360
                     /locus_tag="VQ878_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3095251.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            35868..37361
                     /locus_tag="VQ878_000898"
     CDS             35868..37361
                     /locus_tag="VQ878_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3095252.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37374..>37881
                     /locus_tag="VQ878_000899"
     CDS             37374..>37881
                     /locus_tag="VQ878_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3095253.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT        11462 a         6888 c         8391 g        11140 t
ORIGIN      
        1 agcgaaatta tcgcctataa tctttcaact tcacccaact tagaacaagt acaaacaatg
       61 ttggaacagg cattcacaga gaagcactac gagaatacga ttctccatag tgaccaaggc
      121 tggcaatatc aacacgattc ttatcatcgg ttcttagaga gtaagggaat tcaagcatcc
      181 atgtcacgca agggaaacag ccaagacaat ggtatgatgg agtccttctt tgggattctg
      241 aaatcggaaa tgttttacgg ttatgagaag tcgtttcagt cgcttaagca attggaacaa
      301 gccattatag actatattga ttactacaac aacaagagaa ttaaggtaaa actaaaagga
      361 cttagccctg tgcaatacag aactaaatcc ttcggataaa ttaattgtct aacttttggg
      421 gggcagttca cagaactggc attttatttt ttaggatctt gatgggttag gttcaatccc
      481 caagggacca aattttcagt tttatttttg atacgagcta tattgtcctt atgacgaatg
      541 ataatcaaac tagcaagtgc taagataata gcgatgaaga gagagtcata gttactcagg
      601 ataaaaccaa aaagtggaaa gagcagaacc ccgataacag ccgcgatcga tgctgtgaca
      661 ctagacagtg aaatcatact gccaagatag agagctccaa agaagataat cgcaaggtag
      721 agacagaaga taggcgcaaa tccgaaaatt actccagcac tggttgcgac agccttacca
      781 cctttaaatc ctgcaaagat agggaaggta tggccgataa cagccaaaag tccaaagatg
      841 agaggagaaa cgccttgtag atgaaaaata atcggaagca gcgttgctag ggttcctttg
      901 aaaaagtcaa tcacaaaggt tgccatacca gctttcttac ctaaaatgcg gaaggtattg
      961 gtcgttccag tgttaccaga accatgctcg cgtagattga tttgaaagaa tacttgtcca
     1021 atccagagac cagatggaat cgaacccagc agataggcta ggattaataa aactattgta
     1081 atcatactcc tattatatca tgaattggga aagaaaagca gagaatctct gctaaaattg
     1141 tcacatcgga gaaagaaaaa ttttgcaaaa tccttggaaa acctgtagaa tagtaaagat
     1201 gaacgaatag gaggttcctt gtgtcaaaaa aggaaatcaa tattaacaat tataatgatg
     1261 atgctattca ggtgctagaa gggttggatg cggtccgaaa acgtccaggg atgtatattg
     1321 gatcgaccga tggcgctggt cttcatcacc tagtttggga aatcgttgat aatgcagtcg
     1381 atgaagcctt gtctgggttt ggtgatcgta tcgatgtaac catcaataaa gacggtagtc
     1441 taacggttca agaccatgga cgtgggatgc cgacaggtat gcacgctatg ggaattccaa
     1501 ctgttgaggt tatctttacc attcttcatg ccggagggaa attcggtcaa ggtggctata
     1561 agacatcagg tggacttcac ggagtgggtt cttccgttgt taacgccctt tctagctggt
     1621 tagaagttga aattacccgt gatggcgcag tttacaagca acgtttcgaa aatggtggaa
     1681 aacctgtcac gactttgaag aaaatcggta cagcacccaa gtctaaaaca ggcaccaaag
     1741 ttacttttat gcctgacgcg actatatttt ctacgacaga tttcaagtac aataccattt
     1801 cagagcgcct taatgaatca gcctttctct tgaaaaatgt gaccttgtct ttaacggaca
     1861 agcgaacaga tgaagcgatt gagttccact atgagaatgg agtacaagat tttgtttctt
     1921 atctcaacga agataaggaa atcttgacgc cagttcttta ctttgaaggg gaagacaatg
     1981 gttttcaagt ggaagtagcc ctccagtaca atgacggatt ctcagataac attctatcct
     2041 ttgtcaataa cgttcgcacc aaggacggtg gaacgcacga gacaggactc aagtctgcca
     2101 ttaccaaggt catgaatgac tatgcacgta aaacaggtct tctcaaggaa aaagataaaa
     2161 accttgaagg ttcagactat cgtgagggac tagcggccgt tctttctatc ttagttcctg
     2221 aagaacactt gcagtttgaa ggacagacca aggataaact aggaagcccc ctagctcgcc
     2281 cagttgtgga tggaatagtg gctgataagt tgaccttttt ccttatggaa aatggggaat
     2341 tagcttctaa cctcatccgc aaggctatca aggcccgtga tgctcgtgaa gcagcacgta
     2401 aggcgcgtga tgagagccga aatgggaaga aaaacaagaa agataagggc ttgttgtctg
     2461 ggaaattgac cccagcccaa tctaagaatc ctgctaagaa tgaactctat ctagttgagg
     2521 gggactctgc cggtggttct gccaaacaag gtcgtgaccg caagttccag gctattctac
     2581 ctcttcgtgg taaggttatc aatacagcca aggccaagat ggcggatatc ctcaaaaatg
     2641 aagagatcaa taccatgatt tataccattg gtgcgggtgt tggagcagac ttctctattg
     2701 aagatgccaa ctatgataag atcattatca tgaccgatgc ggataccgac ggtgcccata
     2761 tccagacctt gctcttgaca tttttctacc gttacatgcg tccgctagtc gaggcaggtc
     2821 atgtctatat tgccctccca cctctttaca agatgtccaa aggtaaagga aagaaagaag
     2881 aagtggccta cgcttggacg gacggagaac tagaagaact ccgtaaacag ttcggtaaag
     2941 gcgctaccct ccaacgatac aaaggacttg gtgagatgaa tgcggaccag ctctgggaaa
     3001 caaccatgaa cccagaaaca cgtaccctca tccgtgtcac aattgaagat ttagcgcgcg
     3061 ccgaacgccg cgtcaatgtt ctcatgggag ataaggtaga accacgccgt aaatggattg
     3121 aagataatgt caagtttacg ctagaagaag cgacagtgtt ttaatgaaag aaaataatat
     3181 gttagtaaac tggaaattag agtcggatgt gaatgactat gtgaaaaagc agtttgaaaa
     3241 tcttggtttg aaaaaattgc aggattatta atgaagaatc tgctatgagt gcttatctca
     3301 aagaggcgct taagggagcg gctaagacac aaactaagac taattttgga aaaccagatt
     3361 ttcatattga aaaatacaaa caggatagtt tggttactta tcgtaactga acacgggagg
     3421 aattcccgta aaatatcttt tactgcataa aaacctactc tacattcttt gaaaggagtt
     3481 gaacacgccc tagatactgt gtgaaaaaga taaattctct tgtgagtttg cttacttcaa
     3541 gaattttcta ttttcacttg gtattttatg ggctttgtat cttatgtcta acattcaaaa
     3601 catgtccctg gaggacatca tgggagagcg ctttggtcgc tactccaagt acattattca
     3661 agaccgggct ttgccagata ttcgtgatgg gttgaagccg gttcagcgcc gtattcttta
     3721 ttctatgaat aaggatagca atacttttga caagagctac cgtaagtcgg ccaagtcagt
     3781 cgggaacatc atggggaatt tccacccaca cggggattct tctatctatg atgccatggt
     3841 tcgtatgtca cagaactgga aaaatcgtga gattctagtt gaaatgcacg gtaataacgg
     3901 ttctatggac ggagatcctc ctgcggctat gcgttatact gaggcacgtt tgtctgaaat
     3961 tgcaggttac cttcttcagg atatcgagaa aaatacagtt ccttttgcat ggaactttga
     4021 cgatacggag aaagaaccaa cggtcttgcc agcagccttt ccaaacctct tggtcaatgg
     4081 ttcgactggg atttcggctg gttatgccac agacattcct ccccataatt tagctgaggt
     4141 catagatgct gcagtttaca tgattgacca cccaactgca aagattgata aactcatgga
     4201 attcttgcct ggaccagact tccctacagg ggctattatt cagggtcgtg atgaaatcaa
     4261 gaaagcttat gagactggga aagggcgcgt ggttgttcgt tccaagactg aaattgaaaa
     4321 gctaaaaggt ggtaaggaac aaatcgttat tactgagatt ccttatgaaa tcaataaggc
     4381 caatctagtc aagaaaatcg atgatgttcg tgttaataac aaggtagctg ggattgctga
     4441 ggttcgtgat gagtctgacc gtgatggtct tcgtatcgct atcgaactta agaaagacgc
     4501 taatactgag cttgttctca actacttatt taagtacacc gacctacaaa tcaactacaa
     4561 ctttaatatg gtggcgattg acaatttcac acctcgtcag gttgggattg ttccaatcct
     4621 gtctagctac atcgctcacc gtcgagaagt gattttggcg cgttcacgct ttgacaaaga
     4681 aaaggctgag aaacgtctcc atatcgtcga aggtttgatt cgtgtgattt cgattttgga
     4741 tgaagtcatt gctcttatcc gtgcttctga gaataaggcg gacgccaagg aaaacctcaa
     4801 agttagctat gattttacgg aagaacaggc tgaggctatc gtaactttgc aactgtaccg
     4861 tttgaccaat accgatgtgg ttgtcttgca ggaagaagaa gcagagcttc gtgagaagat
     4921 tgctatgctg gcggctatta tcggtgatga aaggactatg tacaatctca tgaagaaaga
     4981 acttcgtgag gtcaagaaga aatttgcaac tcctcgtttg agttctttag aagacactgc
     5041 gaaagcaatt gagattgata cagctagtct tatcgctgag gaagatacct acgtcagcgt
     5101 gaccaaggca ggttacatca agcgtaccag tccacgttcc tttgcggctt ccaccttgga
     5161 agaaattggc aagcgtgatg atgaccgttt gatttttgtt caatctgcca agacaaccca
     5221 gcacctcttg atgttcacaa gtcttggaaa tgtcatctac agaccaatcc atgagttggc
     5281 agatattcgt tggaaggaca tcggagagca tctgagccaa accatcacaa actttgaaac
     5341 gaatgaagaa atcctttatg tggaagtact ggatcagttt gacgatgcga caacctactt
     5401 tgcagtgact cgccttggtc aaatcaaacg ggtagagcga aaagaattca ctccatggcg
     5461 gacctataga tctaagtctg tcaagtatgc taagctcaaa gacgatacag atcagattgt
     5521 agcagtggct ccgattaaac tagatgatgt tgtcttggtt agtcaaaatg gttatgccct
     5581 gcgtttcaat atcgaagagg ttccggttgt cggtgctaag gcagcaggtg tcaaggctat
     5641 gaatttgaaa gaagatgatg tcctccaatc tggctttatc tgtaatactt cgtccttcta
     5701 cctcttgacc cagcgtggaa gcttgaaacg tgtttctatt gaggaaattc tagcaaccag
     5761 ccgtgccaaa cgaggattac aagtcttgcg tgagttgaaa aacaaaccgc atcgtgtctt
     5821 cttggcagga gcagttgcag agcaaggatt tgttggcgat ttcttcagta cggaagtgga
     5881 tgtgaacgac caaactctgc ttgtccaatc caataaagga acaatctatg aaagccgatt
     5941 gcaagacttg aacttgtcag aacgcactag caatggaagc ttcatttctg acacgatttc
     6001 agatgaagaa gtttttgacg cttatcttca ggaagtagtt actgaagata aataagtgaa
     6061 atgaagaatc agttctaaga gctggttttt attggagaaa ttttctgaaa attacaaaat
     6121 atacttgcta ttttagaaaa atagtgtaga atataagaaa taggttttta gaataaggag
     6181 tggaatatga cagtaacgat tgattgggaa aacctcggtt tttcctatat gaaattacct
     6241 tatcgctatc ttgctcattt caaaaatgga caatgggatc aaggagagct tacagaggat
     6301 gcaactttgc atatttcaga gtcttctcca agtcttcact atggacaaca agcatttgaa
     6361 ggtttgaaag cttatcgtac taaggatggc agtgttcaac tgttccgtcc tgatgaaaat
     6421 gctaaacgtc tgcaacgtac atgtgaccgt ctcttgatgc cacaagttcc gacagacatg
     6481 tttgtagaag cttgtaaagc agttgtccgt gcgaatgaag aatacgtacc accatacgga
     6541 acaggtggaa ccttatatct tcgccctctt ttgattggtg tcggagatat tatcggggta
     6601 aaaccggcag aagagtacat tttcaccatc tttgctatgc cagttggaaa ttactttaaa
     6661 ggtggtttgg tcccaaccaa cttcttgatt caggatgagt acgaccgtgc agcaccaaat
     6721 ggtacaggtg cggctaaggt tggtggaaac tatgctgcaa gtctcttacc aggaaaaatg
     6781 gccaagtcac gtcatttctc agatgttatc tatctggacc catcaactca tacaaagatt
     6841 gaagaagtcg gatcagctaa cttctttgga attacagctg ataatgaatt tgtaacacca
     6901 ttgagtccat ctatcttgcc atctattacc aagtattcct tgctttattt ggcagaacat
     6961 cgcttgggat taactcctat tgagggtgat gttccaattg ataatcttga ccgttttgta
     7021 gaggcaggtg cctgtggtac agcagcggtt atttctccaa ttggaggtat tcaacatggt
     7081 gatgatttcc atgtattcta tagtgaaaca gaagtaggtc ctgtgacgcg taaattatat
     7141 aatgaattga cgggtattca gtttggcgat attgaagcgc cagaaggttg gattgtaaaa
     7201 gtagattaaa ataaaccaaa ggagattttt tatgaaatag aaaaagtggc tcttaacagc
     7261 aggagtggtc ctgagcacgt cagctatttt agtggcttgt ggaaaaactg ataaagaagc
     7321 agatgcaccg acaacatttt cttatgtcta tgcagtagat ccagcatcat tgggctacag
     7381 tatagcgact cgaacatcga ggacagacgt tattggaaat gttattgatg gtttgatgga
     7441 aaatgataaa tacggcaatg ttgctccttc tcaaaaagac tatgatttga acggtacagg
     7501 atgggctcca agctatcaag atccagcgtc ttacttgaat attatggatc caaaatctgg
     7561 ttctgccatg aaacaccttg gcattacgaa aggaaaagat aaggatgttg tagctaaacc
     7621 tggtttggat aaatataaga aattgttaga agatgctgtt tctgagacca ctgacctaga
     7681 gaagagatat gaaaaatatg ccaaagctca agcttggtcg acagatagtt cattattgat
     7741 gccaacagct tcatctggtg gttttccagt tgtaagtaac gtagtaccat tctcaaaacc
     7801 atactcacaa gttggtatta agggggaacc atatatcttt aaaggaatga aattgcaaaa
     7861 agatattgtt acaacaaaag aatataacga ggtttttaaa aaatggcaaa aagaaaaatt
     7921 ggaatccaat agcaaatacc aaaaagaact agaaaaatac attaaataag gaatggtatt
     7981 gatcttgata aaatttttaa aatactgtca ttttgaatat aaaggagttt gatatggagt
     8041 ggattagatt aataggaata gcaatcattg ttgtgggttt tattttaaaa tttgatacaa
     8101 ttgcaacagt agtcttagct ggtttggtta cagctttagt ttcaggtgtt tctctcgttg
     8161 aatttttgga gattttggga aaagaattta gcaatcagcg agtgctcacg atttttatgg
     8221 ttaccttgcc tcttgtgggg ctgtcagaaa cctttggact caagcaacga tcaatcgatt
     8281 tgattcgaaa gattaaaggt ctgacagttg gaaacttcta tacagtttat ttctttattc
     8341 gagagttagc tggtttcttt tcaattcgtc taggaggaca ccctcagttt gtcagacctt
     8401 tggttcaacc tatgggagaa gcagctgcag agtctcaatt aggtagaaag ttaacagagg
     8461 ttgaagatga gacaataaaa gcgcgtgcgg ctgcgaatga aaattttgga aatttctttg
     8521 ctcaaaatac gtttgtaggt gctgggggag tcctcttgat agggggaaca ttagatcagt
     8581 taggctatga aagcaattat gcagggattg cttctacatc tattattgtt gctgttataa
     8641 cacttattgt agtggggatt tacaattatt tatttgataa aaaattgata tcaaaaaaga
     8701 ctaggggagg agaacaaaaa tgacagagtt ggcaaagcaa ctattagagt tgacctatat
     8761 tgtgattggt tgtcaatttc tccatacagc ctattgtagt tataaagata aaacaaaccc
     8821 agttcgactt gggacatctg cattttggac tctattgtct attacgttta taggtggttc
     8881 ctatatgcca aatatgagta ttggtattat tgtaatccta ttatcgctgt taacattgtt
     8941 taagcaagtc cgtatcggaa ccttgccatc cttagatgaa atgaaagcca atattgaatc
     9001 taacaggttg aaaaataaaa tttttattcc agttatgctg atggcaatac ttgcgttggt
     9061 cttagcgcaa atgattccag aatttagcaa gatttcgatt agccttgccg ccttgtttgc
     9121 tacaatttct gttcttgtga ttaccaatag tcaccctaag agtctgttat cagaaaataa
     9181 tcgaatgact cagcaagttt caacaagtgg tattgttcct caattattag gggctttggg
     9241 ggctattttt actgtagcag gtgttggtga tgttatctct catctgatta gcggtattgt
     9301 tccttcagat agtcgcttta taggagtttt ggcttatgtt cttggaatgg ttctattcac
     9361 aatgattatg ggaaatgctt ttgcagcatt caccgttatt acagcaggtg ttggagttcc
     9421 ctttgtattt gctctgggag ctaatccaat tgtggctggt gctcttgcca tgacagcagg
     9481 ttattgtggg accttattga ccccaatggc tgctaatttt aacgctctac cagcagcatt
     9541 gatggatatg aaagatcaga atggcgttat aaaggctcaa gcaggtgttg ctctagtaat
     9601 gattgttatt cacatattct taatgtactt tctcgcattt tagtaaagga aaataaaatg
     9661 aaaatattgg ttacaggttt taatcctttt ggaggtgaaa agattaatcc agctttggag
     9721 gctgtaaaat tattaccatc tgagattaat ggggctgaag ttcgctgggt agaaattcca
     9781 acggtttttt ataagtcgtc agaagtttta gaggcagaaa tattacgata tcaaccagat
     9841 gctgtacttt gtattggaca agcaggcggc aggaccggct taacacctga acgagtggct
     9901 attaatcaag atgatgctcg catacctgat aacgaaggca atcaaccaat tgatacaccg
     9961 attcgtattg atggagcatc ggcctatttt agtagtttac ctatcaaagc gatggtacaa
    10021 gctatcaaaa aacagggact tccggcagtt gtatccaata gtgcaggaac ctttgtttgc
    10081 aatcatttga tgtaccaagc tctttattta gtggataaaa aattccctaa tatgagagca
    10141 ggtttcatgc atattccata tatgatggaa caagtagtaa ataagccgaa tactgcagga
    10201 atgagtctat gtgatattgt aagaggcata gaggtagcta ttgaagctat tgtagactac
    10261 aaagataagg atttgcagtt agtaggcggt gagactcact gataacctaa aaaggatagt
    10321 caattatgct tgtttactaa ctattaacta tgctaaatca attgaggttg tttacataaa
    10381 actctatatc agagaagcct gatatagagt tttttcttgc tagttttagg attttcttgt
    10441 aaaatagaaa aagtgaagag aggtatgaaa tgagcaagaa agataaaaaa atcgaaattc
    10501 aagtagcgga tgccaaagtt aatgttggta aagacagttt tgaaggttat acattgacta
    10561 tcggtaaaaa agttatcgga gaaattgtcg aattagacgg acaatttgcc attataaaga
    10621 atgggaatgt cgatagtttt tataaaaaat tggaaaaagc tgtggaaatt ttgattgaaa
    10681 attataattt agcaaaataa gtcttgtttt tttgaaattt tcatgatata atagtccatg
    10741 ttgattgtag gagagatagc gaagaggcta aacgcggcgg actgtaaatc cgctccttcg
    10801 ggttcggggg ttcgaatccc tctctctcca tttcattaat ggggtatagc caagcggtaa
    10861 ggcaagggac tttgactccc tcatgcgttg gttcgaatcc agctacccca gttcttaggt
    10921 aataatcaag ataaaaagca aaatatctta gggtatttta tttttataat tgaaagacgt
    10981 gaatgatatg aacatgtcct tgcgggtgct taggaaaaaa attataagta tgtcaagttt
    11041 aagaaaaact tgattgttgg aggatttttt agatgaacga atttgaagat ttgctaaata
    11101 gcgttagtca agttgagact ggtgatgttg ttagtgctga agtattgaca gttgatgcga
    11161 ctcaagctaa cgttgcaatc tctggaactg gtgttgaagg tgtcttgact cttcgcgaat
    11221 tgacaaacga tcgtgatgca gatatcaatg actttgttaa agtaggagaa gtattggatg
    11281 ttcttgtact tcgtcaagta gttggtaaag atactgatac agttacatac cttgtatcta
    11341 aaaaacgcct tgaagctcgc aaagcatggg acaaacttgt tggtcgcgaa gaagaagttg
    11401 ttactgttaa aggaacgcgt gccgttaaag gtggactttc agtagaattt gaaggtgttc
    11461 gtggatttat cccagcttca atgttggata ctcgtttcgt acgtaacgct gagcgttttg
    11521 taggtcaaga atttgatact aaaatcaaag aagttaacgc taaagaaaac cgcttcatcc
    11581 tttcacgtcg tgaagttgtt gaagcagcta ctgcagcagc tcgcgctgaa gtattcggta
    11641 aattggctgt tggtgatgtt gtaactggta aagttgctcg tatcacaagc ttcggcgctt
    11701 tcatcgacct tggtggtgtt gacggattgg ttcacttgac tgaattgtca catgaacgta
    11761 acgtatcacc aaaatcagtt gtaactgttg gtgaagaaat tgaagtgaaa atccttgatc
    11821 ttaacgaaga agaaggacgt gtatcacttt cacttaaagc aacagtacca ggaccatggg
    11881 atggcgttga gcaaaaattg gctaaaggtg atgtagtaga aggaacagtt aaacgtttga
    11941 ctgacttcgg tgcatttgtt gaagtattgc caggtatcga tggacttgtt cacgtatcac
    12001 aaatttcaca caagcggatt gaaaatccaa aagaagctct taaagttggt caagaagttc
    12061 aagttaaagt tcttgaagtt aacgcagatg cagaacgcgt gtcactttct attaaagctc
    12121 ttgaagaacg tccagcccaa gaagaaggac aaaaagaaga aaaacgtgct gctcgtccac
    12181 gtcgtccaag acgtcaagaa aagcgtgatt tcgaacttcc agaaacacaa acaggatttt
    12241 caatggctga tttgtttggt gatatcgaac tttaatcaaa ttgaaaattc acaaaatcct
    12301 ttgtttacta aacaagggat ttttcttttg tctctgctcc ttttttgata taatagttct
    12361 atgttaaaat cagaaaaaca atcacgttat caaatgttaa atgaagaatt gtccttccta
    12421 ttggaaggcg aaaccaatgt tttggctaat ctttccaacg ccagtgctct tataaaatca
    12481 cgttttccta ataccgtatt tgcaggcttt tatttgttcg atggaaagga attggtttta
    12541 ggtcccttcc aaggaggtgt ttcctgcatc cgtattgcac taggcaaggg tgtttgtggt
    12601 gaggcagctc actttcagga aactgttatt gttggagatg tgacgaccta tctcaactat
    12661 atttcttgtg atagtctagc taaaagtgaa attgtggtgc cgatgatgaa gaatggtcag
    12721 ttacttggag ttctggatct ggattcttca gagattgagg attacgatgc tatggatcga
    12781 gattatttgg aacaatttgt cgctattttg cttgaaaaga caacatggga ctttacgatg
    12841 tttgaggaaa aatcttaatg tatcaagcac tttatcgaaa atatagaagt caaaacttct
    12901 cccagttagt tggtcaagaa gttgtggcta agactcttaa acaagcggtg gagcaagaga
    12961 aaataagtca cgcttatctt ttttctggtc ctcgtggaac gggaaaaacc agtgttgcta
    13021 aaatctttgc caaggctatg aactgtccca atcaagtggg tggcgaacct tgcaataact
    13081 gctatatttg tcaagcagtg acggacggta gtttagaaga tgtcattgaa atggatgcag
    13141 cttctaataa tggggtagat gaaattcgcg aaattcgtga taaatctacc tatgcgccta
    13201 gccttgctcg ttataaggtt tatatcatag atgaggttca catgctgtct acaggggctt
    13261 ttaatgccct cctaaagacg ctggaagaac caacacagaa tgtagtcttt attttggcca
    13321 ctactgaatt gcacaagatt cctgctacta ttctatcccg tgtgcaacgt tttgagttta
    13381 aatcaattaa gacacaggat attaaggaac atattcacta tatcttagaa aaagaaaata
    13441 tcagttctga accagaggct gtggaaatca ttgccagacg ggcggaaggt ggaatgcggg
    13501 acgccttgtc tattttggat caagccctga gtttgacaca gggaaatgag ctgacgactg
    13561 ctatctctga agaaattact ggcaccatta gcctatcagc cttggatgat tatgtggcgg
    13621 ccttgtctca acaggatgtt cccaaagctt tgtcttgctt gaatcttctt tttgacaatg
    13681 gtaagagcat gactcgtttt gtgaccgatc ttttgcacta tttaagagac ttgttaattg
    13741 ttcaaacagg gggagaaaat actcatcata gttcagtctt tgtagaaaat ttggcacttc
    13801 ctcaaaaaaa tctgtttgaa atgattcgct tagcaacagt gaatttagca gatattaagt
    13861 ctagtttgca gcccaagatt tatgctgaaa tgatgaccgt ccgtttggcg gaaatcaagc
    13921 ccgaaccagc tctatcagga gcggttgaaa atgaaattgc tacgctgaga caggaagttg
    13981 cccgtctcaa acaagagctt tctaatgcag gtgcggttcc taaacaagtt gcaccagctc
    14041 ctagtcgacc agctacgggc aaaacagtct atcgtgtcga tcgcaataaa gtgcaatcta
    14101 tcttacaaga ggccgtcgaa aatcctgatt tagcacgtca aaatctaatt cgtttgcaga
    14161 atgcctgggg agaggtaatt gaaagtctag gtgggccgga caaggctctg ctagttggtt
    14221 ctcaaccggt tgctgccaat gaacaccatg ctattcttgc ttttgagtct aacttcaatg
    14281 ctggtcaaac tatgaaacga gacaatctca ataccatgtt tggtaatatc ctcagtcagg
    14341 cggcaggttt ttcacctgag attttagcta tttccatgga ggaatggaaa gaagttcgcg
    14401 cagccttttc agccaaagcc aaatcttctc aaactgaaaa agaagtagaa gaaagcctga
    14461 ttccagaagg atttgaattt ttggctgata aagtgaaggt agaggaagac taaagaaaga
    14521 tttcatgata caataagttt atgaataaac aacaatttat tattatggcg ctatttacag
    14581 ctgctgagac ctattttttc aatgaagcct ggatgactgg ccgctatatt atggcagcct
    14641 tttgggcaat tttactcttt agaaatttcc gagtcagtta tgtgatgggt aaaattgttg
    14701 atgtcatcga tcagcatttt aataggaaag actagccctc agcttccaga caaaatcaaa
    14761 gccttttagg cttttttttg ttatactaga aaagtatatt tatagaattt ttgctctatt
    14821 tctggggaaa tcagacgttt ttctagtaag tactgtaaaa gttttgaaaa agaaaggaac
    14881 tatcatgtca gtaatagaga tcaaagatct tcacgttgag attgaaggaa aagaaatttt
    14941 aaaaggggtt aacctgaccc tgaaaacagg agaaattgcc gctatcatgg gaccaaatgg
    15001 tacaggtaaa tcgactcttt ctgccgctat catgggaaat ccaaactatg aagtaactaa
    15061 aggtgaagtt ttgtttgatg gcgtaaacat ccttgagttg gaagtggatg agcgtgcgcg
    15121 tatgggactt ttccttgcta tgcaataccc atcagaaatc cctggaatta ccaatgctga
    15181 gtttcttcgt gccgctatga atgcgggtaa agaagatgat gagaagattt cagttcgtga
    15241 gtttattact aagctagatg aaaaaatgga attgctcaac atgaaagaag aaatggcaga
    15301 gcgttacctc aacgaaggct tctctggtgg tgagaaaaaa cgcaatgaaa ttcttcaact
    15361 tttgatgttg gagccaacat ttgctctttt ggacgagatt gactcaggtc ttgatattga
    15421 cgctcttaaa gttgtgtcta aaggtgtcaa tgccatgcgt ggtgaaggtt ttggtgctat
    15481 gatcatcact cactaccaac gtcttttgaa ctatatcaca cctgatgtgg tacacgtgat
    15541 gatggaaggt cgtgttgtcc tttctggtgg tccagaattg gctgcgcgtt tggaacgtga
    15601 aggatacgca aaattagctg aagaacttgg ctacgactac aaggaagaat tgtaatttcc
    15661 tcgtatcttt taggagaagt aaatgactag agaaaatatt aaactttttt cagaaatgca
    15721 cgctgaacca agctggttgg ctgatctccg tcaaaaagct tttgacaaga ttgagacttt
    15781 ggaattacca gttattgagc gtgtcaaatt ccaccgttgg aatctgggtg atggaacgat
    15841 tacagaaaat gagccatcag caaatgttcc agatttcaca gctttagatc atcacttgaa
    15901 gttggtgcaa gtaggaactc aaactgtttt cgaacaaact ccagttgagt tagctgaaca
    15961 gggtgttgtc ttcacagact ttcactcagc tttagaagaa attccagagc tgatcgaaga
    16021 attcttcatg tcatctgtta agtatgatga tgacaagttg gcggcttacc acacagctta
    16081 ctttaacagt ggtgctgtac tctatattcc agataacgta gaaatcacag agccaattga
    16141 aggaattttc taccaagata gcgatagcaa tgtgccgttt aacaagcata ttatgattat
    16201 cgctggtaaa aattctaaga ttagttatct ggagcgttta gagtcacgcg gtgaaggaag
    16261 tgacaaagca actgccaata tcacagtgga agtgattgca cattctggtg cgcaagtcaa
    16321 gtttgctgct atcgaccgtc taggtgaaaa cgtcactgcc tacattagcc gtcgtggtaa
    16381 attaggcaac gatgcaagta ttgactgggc tatcggtgtc atgaacgaag gaaatgtcgt
    16441 tgctgatttt gatagtgact tgattggtaa tggtagctat gctgacctca aggttgtagc
    16501 tctttcaagt ggtcgtcagg tacaagggat tgatactcgt gtaactaact atggctgcaa
    16561 ctctatcgga aatatcctac aacatggggt tatccttgaa aaagcaactt tgactttcaa
    16621 tggtatcggc cacatcatca agggtgctaa gggagcagat gcccaacaag agagccgtgt
    16681 tctcatgctt tcagaccaag cgcgttcaga tgctaaccca attcttttga ttgatgaaaa
    16741 tgatgtcact gcaggacacg cagcgtctat cggacaagtt gatccagaag acatgtatta
    16801 cctcatgagt cgtggattgg ataaggcaac tgcagagcgt ttggttgttc gtggtttcct
    16861 tggatctgtt atcgtggaga ttccagtcaa ggaagttcgt gatgaaatga ttgcaactat
    16921 cgaagagaaa ttgtcaaaac gctaagggga agcctatgtt agatgtagaa gcgattcgca
    16981 aggattttcc aattttagat cagattgtca atgatgaacc tctggtctat ctggacaatg
    17041 ctgcgacgac acaaaaacca ctagtagttc tgaaagctat taacagttac tatgagcagg
    17101 acaatgccaa tgttcaccgt ggtgtccata ccttagcgga acgagcgaca gcttcttatg
    17161 aagctgctcg tgaaaccatt cgtaagttta ttaatgcagg ctctacaaag gaagttctct
    17221 ttaccagagg aacgacaacc agccttaact gggtggcacg ctttgctgag gaaattctca
    17281 ctgagggaga ccaggtcttg atttcagtaa tggaacacca ttctaatatc attccatggc
    17341 aggaagcttg tcgaaagact ggagcagagc ttgtctatgt ctatcttaaa gacggtgcct
    17401 tggatatgga ggatttgcga gctaaattga ctgataaggt taaatttgtt tccctagctc
    17461 atgcctccaa tgttcttggt gtggtcaatc cgatcaagga aatcactcaa ttagcccacc
    17521 aagttggggc aatcatggta gtggatggtg ctcaatctac acctcatatg aagattgatg
    17581 tccaggactt ggatctggac tttttcgcct tttcgggtca caagatggct ggtccgactg
    17641 gtatcggtgt cctttacggc aaagaaaagt atcttgagca aatgtctcca gtagaatttg
    17701 gcggcgagat gattgatttt gtctacgagc aatccgctag ttggaaggaa ttgccttgga
    17761 aatttgaggc tggaacgcca aatatggcag gagctattgg acttgcgact gcagttgatt
    17821 atctggaaaa gattggtatg gatgccgttg aagctcatga acaggaattg attgcgtacg
    17881 tctatccaaa actgcaggca attgagggat tgaccattta cggttctcag gatttggctc
    17941 aacgttcggg tgttattgcc tttaacctag gtgatctcca tcctcacgat cttgcgacgg
    18001 ctctggatta tgaaggagtg gctgttcgtg ctggtcacca ttgtgcgcaa cccttgcttc
    18061 agtatttgga agtctcagca acagctcgtg caagttttta tatctataat accaaggcag
    18121 attgcgacaa actagtcgat gccctacaaa agacaaagga gtttttcaat ggcactttct
    18181 aaactagata gcctttatat ggcagtggta gcagaccatt cgaaaaatcc acatcaccaa
    18241 gggaagttag aagacgctga gcaaatcagt ctcaacaatc cgacttgtgg agatgtcatc
    18301 aatctctctg tcaagtttga tgcagaggac cgtttggaag atattgcttt tctaaattca
    18361 ggatgcacga tttcaactgc ttctgctagt atgatgacag atgccgtttt aggaaaaacc
    18421 aaacaagaaa ttttagaact ggcgactatt ttttctgaaa tggttcaagg gcaaaaagat
    18481 gagcgtcaag accaacttgg agacgcggca ttcttgtcag gtgttgccaa attccctcaa
    18541 agaatcaagt gtgcaaccct agcttggaat gcccttaaga aaacaattga aaatcaagaa
    18601 aaacagtaag acaagtttct tttgtcttat gaattattag aaatgaagaa agaaaggata
    18661 ttatggctga agaaagagta gaaccaaaac caattgacct tggtgaatat aaatttggtt
    18721 tccatgacga tgtagagcct gtcttatcga caggaaaagg actcaacgaa ggtgttattc
    18781 gtgaattatc tgctgctaag ggtgagcctg agtggatgtt ggagttccgt ttgaagtctt
    18841 atgaaacctt caaaaaaatg cccatgcaaa cttggggagc agacttgtca gagattgact
    18901 ttgatgactt aatctactac caaaaaccat ctgacaaacc agcccgttct tgggatgatg
    18961 tacctgaaaa gattaaagaa acctttgaac gtatcgggat tccagaagct gaacgtgctt
    19021 atttagcagg ggcttctgcc cagtacgagt cagaagtggt ttaccacaac atgaaggaag
    19081 agttccaaaa attaggtatt atctttacag atacagattc cgcactcaag gaatacccag
    19141 acttatttaa tcaatacttt gcgaagttgg taccgccgac agataacaag ttggcagccc
    19201 tcaactcagc agtatggtcg ggtggaactt ttatctacgt gccaaaaggt gtcaaggtag
    19261 atattccact tcaaacttat ttccgtatca ataacgaaaa tataggtcag ttcgaacgta
    19321 ccttgattat cgttgatgag ggagcaagcg tccactacgt agaaggatgt acagcaccaa
    19381 catattcaag caatagctta cacgctgcca ttgtagaaat ttttgctttg gacggagctt
    19441 atatgcgtta tacaactatc caaaactggt ctgataacgt ctataacttg gtaacaaagc
    19501 gtgctaaggc tcaaaaggat gccactgttg agtggattga tggaaacttg ggtgccaaaa
    19561 cgactatgaa atatccatct gtttaccttg atggagaagg agcgcgtggt accatgctct
    19621 ctatcgcctt tgctaatgca gggcaacacc aagacacggg tgctaagatg attcacaatg
    19681 ctccacatac cagctcgtct attgtgtcta aatccatcgc taaaggtgga ggaaaggttg
    19741 actaccgtgg acaagtcacc tttaacaaga actctaagaa atctgtttcc cacattgaat
    19801 gtgataccat tatcatggat gacttgtcag catcagatac tattccattt aatgaaattc
    19861 acaactcgca agtggctttg gaacacgaag ccaaagtatc taagatttca gaagagcaat
    19921 tgtattatct catgagccgt ggattgtcag aatctgaggc aactgaaatg attgtcatgg
    19981 gatttgtaga accctttaca aaagaacttc caatggaata cgcagttgag ctgaaccgct
    20041 tgattagcta tgaaatggag ggatcagttg gataaaattt gattttatac tcttcgaaaa
    20101 tctcttcaaa ccacgtcagc atcgccttat cgtatgtatg gttactgact tcgtcagttt
    20161 catctacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta gtttgttctt
    20221 tgattttgaa gatgaacttg tatcaaaaaa tcgcggttta aaatcgcgat tttttataat
    20281 ttctcgttaa caaagcggac aaactgattc caccaaactt ttaagaagaa ggctttttca
    20341 attttcttgt ctgctaccat ttcgaaacta gggcgctctg tggtgatgta accttgacca
    20401 atcaagtcct tgtcttcata agtcaaatgg ccaaccactg ttccagcttc aagtggtgct
    20461 gggattgctt tggaatcagg tgtgaattga acagattgag aagattgatt cccaacacgt
    20521 tcgattagat agatatcctc tggagccact gcagttactg tatcttcttt tccatcttgt
    20581 acaggggctt tgctatcttg ataggcatcg ccttgttgaa cgattttgcg aagtgtaaat
    20641 gtagaagaaa tataatccat tagggaagat gtagctgtaa atcgagcgta aggattattg
    20701 tcttgatgat ctgcatttaa aacaactgtg atgactctca tgcctttttc gacagtagta
    20761 ccaacaaaag actctccagc cttatctgtt gttcctgttt ttagcccatc aaaaccacca
    20821 cggtaagcag gcataccttc taacatgtag ttggttgaag tgattgtcat cccagcaaaa
    20881 gtagaagaag gttttttggt gatttctaag acttgtgggt attttttgat gaggttgcga
    20941 gcaacgatag cgacatcata agcactaagc ttattttcct catctttttt agaacctggg
    21001 taaatgttat cccctagagt ttcattgtta agacctgtcg tattgacaac agtggcatcc
    21061 tgaattcccc attccaagag ttttgcccgc atcatatcga cgaaatcttt ttctgagcca
    21121 gcaattttct cagctagggc aatagcggcg ctgttggcac tagataccag agttgcttca
    21181 agcaactctt cgacagtata attacgggcc tccataggaa tattactggc ttcagaattt
    21241 gtcgtcaatt gataaggata atcagaaata tctacaggag tggagagggt aatacttccg
    21301 ttttccaaag cttcatagac tagataaaca gtaatcaatt ttgttatgga agcaatttcg
    21361 acaggttgcg ttgcatcctt ctcatagaga attttaccag tatttgcctc aacagcaatc
    21421 gcatgtttag cggcaatggt aaaatcttga gcaacagcag tagaaacacc ccctaaaaga
    21481 gagacagtta acaaagttaa aaatattttt ttcatagtag tcttattcta tcataaagaa
    21541 aaaaaatatt cttgctttaa taattcatct gttaagcttt ttgaaaatat ggtaaaataa
    21601 agtgagggag gtaactcatg tttcgtagaa ataaattatt tttttggacc acagaaattt
    21661 tactcttaac catcatcttt tacctatgga gacagatggg atctttgatt aacccttttg
    21721 ttagcgtgct taatacaatt atgattccat ttttattagg gggctttctt tattatttga
    21781 caaaccctat tgttactttc ttaaataaag tctgtaaact caatcgtttg cttggtattt
    21841 taattacctt gtgtactttg gtctggggaa tggtcatagg tgttgtctat ctcttaccta
    21901 ttttgattaa tcagttatct agtttgatta tatctagtca aactatttat agtcgagtac
    21961 aagacttaat catagactta tctaattatc ctgcgctcca gaatttggat gtagaagcta
    22021 caattcagca gttaaactta tcctatgttg atattcttca aaatatccta aatagcgtat
    22081 caaatagtgt ggggagcgtc ttgtcagctc ttatcagtac tgttttgatt ttgattatga
    22141 ctccagtttt tttggtttat ttcttattag atggacataa attcttgccc atgcttgaaa
    22201 gaacgattct aaagagggat cgcttgcata ttgcaggctt attaaagaat ttaaatgcga
    22261 cgattgctcg ctatattagt ggagtttcga ttgacgcaat cattataggt tgtttggctt
    22321 atattggcta tagtattatt ggtttaaaat atgctttagt ttttgccatt ttttctggtg
    22381 tagccaattt aattccttat gtggggccaa gtattggttt gattcctatg atcatcgcaa
    22441 atatattcac tgatccccat agactgctga ttgcagtgat ttatatgctt gttgttcagc
    22501 aggtagatgg caatatctta tatcctcgaa ttgtaggaag tgttatgaag gttcatccaa
    22561 tcacgatttt agttttactt ttgttgtcaa gcaatatcta tggtgtagtt ggaatgattg
    22621 tcgcagtgcc aacctattct atcttgaaag aaatttctaa gttcttatcc cgtttgtatg
    22681 aaaatcataa aataatgaaa gaacgagaaa gagaattagc taagtaaaag tcaggagaac
    22741 cctgattttt ctttactgga agtggccttt agattagaag actgaaaata agttaaagtc
    22801 ttaaactaat tttcacagct aagaatagta gaagttaatc tgataaaaat cgaaaaaacc
    22861 agtggaattc cgtgtcaggg taagttccac tggttttcat agtctattaa agttcgaatg
    22921 aaacctattt atagtatatt gaaactagaa tagtacacct ctaattctaa aacattgtta
    22981 gaaatcgatt tgactgtcct gatctattcg tcctattctt atttcatttt actatatttt
    23041 ggtgcaataa gtgaaaagta gtccgaataa tataaggatt gattttatag tttttaaact
    23101 caaatgaatt aaaataaaga gagtacgaaa attctcatct gaaagtattt tagaataatt
    23161 ctcttcgtga atttcttcaa aacagatagc ttcatcttag gtatgtgtta attggatttc
    23221 gtaagctcta tttacaatcg taaagttatg cactgaaaaa gttgtagtta gtcttccagt
    23281 ttgctaaatt tctcgaatag tatctttttt aggtatgtga tttctttttg catttttgag
    23341 ttagataagg tataatggtt ttattgtctt ttggggtcgt tacggattcg acaggcatta
    23401 tgaggcatat tttgcgactc gtgtggcgac gtaaacgctc agttaaatat aactgcaaaa
    23461 aataacactt cttacgctct agctgcctaa aaaccagcag gcgtgacccg atttggattg
    23521 ctcgtgttca atgacaggtc ttattattag cgagatacga ttaagccttg tctagcggct
    23581 tgataagaga ttgatagact cgcagtttct agacttgagt tatgtgtcga ggggctgtta
    23641 aaataataca taacctatgg ttgtagacaa atatgttggc aggtgtttgg acgtgggttc
    23701 gactcccacc ggctccatta ttcctttgca ttcttttgca ttccttggta aaacgttgtt
    23761 aaatcaacgt tttttatttt tatctttggt attcctttgc attcttttgc taaaaaggga
    23821 gtcacaaaca gaccctattt taaaaaaagg atagaaaaaa ggatacaaca tttgtcgcat
    23881 cctaaaaata atcttttttc gacggaagac atgggattcg aacccacgca cgctattaca
    23941 cgcctaccgc gtttccaaca cggcctctta agcctcttga gtaatcttcc aatacttact
    24001 caaatagtct accataaagg ctcttatctt gcaataaaaa ttctagaaat aagaaaaatg
    24061 atagattttg aaagaaaatg ataaaaaatg cttgacttca aaagaaagta tgatagaatg
    24121 aatagtgtaa acgataacag gaggtgattc ggtgttaaaa acagagcgga agcaactgat
    24181 tttagaggag ttaaatcaac atcatgtagt ttctctagaa aaattagtta gtttgctaga
    24241 aacgtcagaa tcaacggttc gaagagactt ggatgagttg gaagcggaaa acaagcttcg
    24301 tcgtgtgcat ggtggagcag aactccccca ctccttacag gaagaagaaa ccattcaaga
    24361 aaaatcggtc aaaaaccttc aagaaaagaa gttgctggct cagaaagcag cctctctcat
    24421 taaagaaaaa gatgtcatct ttatcgatgc tggaacaaca actgcttttt tgattcatga
    24481 attggtcaat aagaatgtta cagttgtgac caactccatt caccatgccg ctcagttggt
    24541 tgaaaagcag attccaactg tcatggttgg aggaaacgtc aagacggcga cagatgctag
    24601 tatcgggggc gttgctctta accagattaa ccaattgcac tttgaccgtg cctttatcgg
    24661 aatgaatggt gttgacgatg gctattatac gactcctgat atggaggagg gagctgtgaa
    24721 aagagctatt ttggagaatg ccaagcagac ctacgtcttg gtggattcgt caaaaattgg
    24781 acaaacttgc tttgccaagg tagcaccact caaacgcgct atcgttatca ctagtcaagg
    24841 gcatgagctc ttgcaggtta ttaaggagaa aacggaggta atagaagtat gatttataca
    24901 gtcacactca atccatccat tgactatatc gttcgtttgg accaagtcaa agttggtagt
    24961 gtaaatcgta tggacagtga tgataagttt gctggtggga aaggaatcaa tgtcagccgt
    25021 gtcttgaaac gtttgaatat accaaataca gcgacgggat ttatcggtgg ctttactggt
    25081 aaatttatca cagatacttt agcagaggaa gaaatcgaga cacgttttgt ccaggtggca
    25141 gaagatactc gtatcaatgt taaaatcaaa gcagaccaag aaacagaaat caacggaacg
    25201 ggtccaactg ttgaaccggt tcagctagaa gaattgaaag ctattttatc tagtctgaca
    25261 gcagaagata cagttgtctt tgcaggttca agtgctaaaa atctaggcaa tgttatctat
    25321 aaggatttga tttccttgac gcgccagact ggtgcgcaag tggtctgtga ctttgaagga
    25381 cagaccttaa ttgatagttt ggactaccag cctcttcttg taaaaccaaa caatcatgaa
    25441 cttggagcga tttttggggt taaactcgaa agtttagatg aaattgagaa atacgctcgt
    25501 gagttactgg ctaagggtgc tcaaaatgtt attatctcta tggctggtga tggcgccctt
    25561 cttgtcacat ctgagggagc ttacttcgct aaaccaatca aaggaacagt caaaaattca
    25621 gttggagctg gtgattctat ggttgctgga ttcacaggtg aatttgtcaa atcaaaagac
    25681 gcagtagaag ccttcaaatg gggagtggct tgcggaacgg caactacctt ctcagatgac
    25741 ttggcaacgg cggaatttat taaagaaaca tatggaaaag ttgaggtaga aaaaagatga
    25801 aaattcaaga cctattgaga aaagatgtca tgttgctaga tttgcaggca actgaaaaaa
    25861 cagctgtcat cgacgagatg attaaaaatt tgacagagca cggttatgta acagattttg
    25921 aaacatttaa agaaggaatt ttggcgcgtg aagctttgac ttctactggt ttgggtgatg
    25981 gaatcgcaat gcctcacagc aaaaacgctg ctgtcaaaga agcgacagtt ctatttgcta
    26041 agtcaaataa gggtgttgac tacgagagct tggatggaca agcaactgac ctcttcttca
    26101 tgattgcagc tccagaaggt gccaatgata ctcacttggc agccttggca gaattgtctc
    26161 aatacttgat gaaagacggt tttgcagaca aacttcgtca agcaacatct gcagaccaag
    26221 ttatcgaact ttttgaccaa gcttcagaaa aaactgagga acttgttcaa gcacctgcta
    26281 atgactctgg tgactttatc gtagctgtta cagcttgtac aacaggtatt gcccacactt
    26341 acatggccca agaagccctt caaaaagtag ctgctgaaat gggggttggt atcaaggtcg
    26401 aaaccaacgg tgctagcggt gttggaaatc aactaactgc agaagatatc cgtaaggcta
    26461 aagctattat cattgcagca gacaaggccg ttgaaatgga tcgatttgat ggaaaaccat
    26521 tgatcaatcg tccagttgct gacggtatcc gtaagacaga agagctaatt aacttggctc
    26581 tttcaggaga tactgaagtc taccgtgccg ctaatggtgc caaagctgca acagcctcta
    26641 acgaaaaaca aagccttggt ggtgccttgt acaaacactt gatgagtggt gtatctcaaa
    26701 tgttaccatt cgttatcggt ggtggtatca tgattgccct tgccttcttg attgacggtg
    26761 ctttgggtgt tccaaatgaa aaccttggca atcttggttc ttaccatgag ttagcttcta
    26821 tgttcatgaa aattggtgga gctgcctttg gtttgatgct tccagtcttt gcgggttatg
    26881 ttgcctactc tattgctgaa aaaccgggtt tggtagcagg tttcgtggct ggtgctattg
    26941 ccaaagaagg ttttgccttt ggtaaaattc cttatgccgc aggtggtgaa gcaacttcaa
    27001 ctcttgcagg tgtctcatct ggtttcctag gtgcccttgt tggtggattt atcgcaggtg
    27061 ccttggttct tgccatcaag aaatacgtta aagttcctcg ttcactcgaa ggtgctaaat
    27121 caatccttct attgccactt cttggaacaa tcttgacagg atttgttatg ctagctgtga
    27181 atatcccaat ggctgcaatc aacactgcta tgaatgactt cctaggcggt cttggaggag
    27241 gttcagctgt ccttcttggt atcgtccttg gtggaatgat ggctgttgac atgggtggac
    27301 cagttaataa agcagcttat gtctttggta caggtacgct tgcagcaact gtttcttcag
    27361 gtggttctgt agccatggca gcagttatgg ctggaggaat ggtgccacca cttgcaatct
    27421 ttgtcgcaac tcttcttttc aaagataaat ttactaagga agaacgtaac tctggtttga
    27481 caaacatcat catgggcttg tcatttatca ctgagggagc gattccattt ggtgccgctg
    27541 acccagctcg tgcgattcca agcttcatcc ttggttcagc agtagcaggt ggactcgttg
    27601 gtcttactgg tatcaaactc atggcgccac acggaggaat cttcgttatc gcccttactt
    27661 caaatgctct cctttacctc gtttctgtct tggtaggagc aatcgtaagt ggtgtggttt
    27721 atggttacct acgcaaacca caagcataaa aaatagaaaa atgaaaagat tggaccgttt
    27781 ggtgcagtct ttttctcttc ccgaaatgcc tgtgaaatat ggtataatag aagaatggca
    27841 aacaagaata caagtacaac aagacggaga ccgtctaaag cagaactgga aagaaaagaa
    27901 gcgattcaac gaatgttgat ttcgttagga attgcgattt tattgatttt cgcagccttc
    27961 aaattagggg ctgcaggtat aaccctttat aatttaattc gcttgctagt gggtagccta
    28021 gcttatctgg cgatattcgg cctattaatc tatctcttct ttttcaagtg gatacgaaaa
    28081 caggaaggac tcttatctgg ctttttcacc atatttgctg gcttactctt gatttttgag
    28141 gcctacttgg tttggaaata tggtttggac aagtccgttc taaaagggac catggctcag
    28201 gttgtgacag atctgactgg ttttcgaacg actagctttg ctggaggggg cttgatcggg
    28261 gtcgctcttt atattccaac agcctttctc ttttcaaata tcggaactta ctttattggt
    28321 tctatcttga ttttagtggg ttctctccta gtcagccctt ggtctgttta cgatattgct
    28381 gaatttttca gtagaggctt tgccaaatgg tgggaagggc acgagcgtcg aaaagaggaa
    28441 cgctttgtca aacaagaaga aaaagctcgc caaaaggctg agaaagaggc tagattagaa
    28501 caagaagaga ctgaaaaagc cttactcgat ttgcctcctg ttgatatgga aacgggtgaa
    28561 attctgacag aggaagctgt tcaaaatctt ccacctattc cagaagaaaa gtgggtggaa
    28621 ccagaaatca tcctgcctca agctgaactt aaattccctg aacaggaaga tgactcagat
    28681 gacgaagatg ttcaggtcga tttttcagcc aaagaagccc ttgaatacaa acttccaagc
    28741 ttacaactct ttgcaccaga taaaccaaaa gatcagtcta aagagaagaa aattgtcaga
    28801 gaaaatatca aaatcttaga agcaaccttt gctagctttg gtattaaggt aacagttgaa
    28861 cgggccgaaa ttgggccatc agtgaccaag tatgaagtca agccggctgt tggtgtaagg
    28921 gtcaaccgca tttccaatct atcagatgac ctcgctctag ccttggctgc caaagatgtc
    28981 cggattgaag caccaatccc tgggaaatcc ctaatcggaa ttgaagtgcc caactccgat
    29041 attgccactg tatctttccg agaactatgg gaacaatcgc aaacgaaagc agaaaatttc
    29101 ttggaaattc ctttagggaa ggctgttaat ggaaccgcaa gagcttttga cctttctaaa
    29161 atgccccact tgctagttgc aggttcaacg ggttcaggga agtcagtagc agttaacggc
    29221 attattgcta gcattctcat gaaggcgaga ccagatcaag ttaaatttat gatggtcgat
    29281 cccaagatgg ttgagttatc tgtttacaat gatattcccc acctcttgat tccagtcgtg
    29341 accaatccac gcaaagccag caaggctctg caaaaggttg tggatgaaat ggaaaaccgt
    29401 tatgaactct ttgccaaggt gggagttcgg aatattgcag gttttaatgc caaggtagaa
    29461 gagttcaatt cccagtctga gtacaagcaa attccgctac cattcattgt cgtgattgtg
    29521 gatgagttgg ctgacctcat gatggtggcc agcaaggaag tggaagatgc tatcatccgt
    29581 cttgggcaga aggcgcgtgc tgcaggtatc cacatgattc ttgcaactca gcgtccatct
    29641 gttgatgtca tctctggttt gattaaggcc aatgttccat ctcgtgtagc atttgcggtt
    29701 tcatcaggaa cagactcccg tacgattttg gatgaaaatg gagcagaaaa acttcttggt
    29761 cgaggagaca tgctctttaa accgattgat gaaaatcatc cagttcgtct ccaaggctcc
    29821 tttatctcgg atgacgatgt tgagcgcatt gtgaacttca tcaagactca ggcagatgca
    29881 gactacgatg agagttttga tccaggtgag gtttctgaaa atgaaggaga attttcggat
    29941 ggagatgctg gtggtgatcc gctttttgaa gaagctaagt ctttggttat cgaaacacag
    30001 aaagccagtg cgtctatgat tcagcgtcgt ttatcagttg gatttaaccg tgcgacccgt
    30061 ctcatggaag aactggagat agcaggtgtc atcggtccag ctgaaggtac caaacctcga
    30121 aaagtgttac aacaataaaa aaatagcttc tttccaagtt tggagggaag ctatttttct
    30181 ggctattgat tacttttata ctcttcgcaa atctcttcaa accacgtcag cttcgccttg
    30241 ccgtactcaa gtactgtcta cggctagctt cctagtttgc tctttgattt tcattgagta
    30301 ttattttctg aagttggagt attgggctgt ttttcatttt cagtggcagg tttacttgta
    30361 gcaggtgtag tagagtcctg agttgctgtt ttctgatctt cttttttctc ttccttgacg
    30421 ctagattttg gcgtttcttc ttgttgtgtt ttttcttgag aagtgttatt ttccttattt
    30481 ggagtagtat tttcctgagg ggattctttt tgaatttctt tgacaaaggt tgtcgtctgg
    30541 cttgtcgtag gttctttttt agtattttta ttattattat ccaaggcgtt catgatcgtg
    30601 atacccgcgg taatcaaacc aaggatacta ccgatagtag taatggtttt ttgaaaaaca
    30661 gtaaagcctt ttttgatatg ttctgttttc ggttttgaag ttctacgata gttagacata
    30721 cattctctcc tttgattatg atttattata ctctgtttct ttaaaaaaat cttaaaaaaa
    30781 gagaaattgc cctttcttgt cgcaggctcc gtttcatgat acaatagaag gagtgatttt
    30841 agaaagcgtg agaaacatga tttactttga taattcggcg acgaccaggc cctatccaga
    30901 agcccttgaa acctatatgc aggtggcttc aaaaatttta ggaaatccat ctagtctcca
    30961 tcgtttggga gaccaggcaa cacgaatttt agatgcttcc cgtcaacaga ttgcagattt
    31021 aatcggtaag aaaagtgatg aaatcttctt tacatctggt gggacagaag gggataactg
    31081 gatcatcaag ggagtagcat ttgaaaaagc ccagtttggc aagcacatca tcgtatcagc
    31141 cattgaacat ccagcagtta aggaatcagc cctctggttg aaagctcaag gttttgaagt
    31201 ggattttgct ccagttgata acaaaggatt tgtggatgtt gaggcgctag aagatttgat
    31261 aagacctgat acgaccctcg tttccatcat ggctgtgaac aatgaaatcg gctctatcca
    31321 acctattgag gctatttcag aattcttggc agacaagcca actatttcct tccacgttga
    31381 tgcggttcag gcgcttgcca agattccgac tgaaaagtat ctgacagaac gagtggattt
    31441 cgcgactttc tctggtcaca agttccacgg aatccgtggt gttggtttta tctatatcaa
    31501 gtctggcaag aagattacgc ctcttttaac aggtggtggt caggaacgtg attaccgttc
    31561 gacaactgaa aatgtggcag gaattgcagc gaccgctaag gctctccgtt tatctatgga
    31621 aaagctagat atctttagga gcaagactgg gcagatgaag gcagtgattc gtcaagcact
    31681 tctggactat ccggatatat ttgtcttttc agatgaggaa gacttcgccc ctcatattct
    31741 gacttttgga atcaagggtg ttcgtggtga ggtcattgtt cacgcctttg aagactatga
    31801 tattttcatc tcaacgacct cggcttgttc gtccaaggct gggaaaccag ccggaaccct
    31861 gattgctatg ggagtggaca aggataaggc tcagtcagct gtgcgtctta gtctagacct
    31921 tgaaaatgat atgagtcagg tcgagcagtt cttgaccaag ctaaaattaa tttacaatca
    31981 aactagaaaa gtaagatagg agcattcatg cagtattcag aaattatgat tcgctacggt
    32041 gagctgtcaa ccaagggcaa aaatcgtatg cgtttcatca ataaacttcg caataatatt
    32101 tcagacgttt tgtctatcta tccccaagtt aaggtaacag cagatcgcga ccgtgcccac
    32161 gcttacctca atggagcaga ttacacagca gtagcagaat cgctcaaaca agtatttgga
    32221 attcaaaact tttcccctgt ttataaggtt gaaaaatctg tagaagttct gaagtctgct
    32281 gtccaagaga ttatgcagga catctacaag gaaggcatga cctttaaaat ctctagcaag
    32341 cgtagcgacc acacctttga attggacagt cgtgaactca accaaacgct tggaggggct
    32401 gtattcgaag ccattccaaa cgtacaagct caaatgaaaa gtcctgacat caatcttcag
    32461 gtggagatac gtgaagaagc agcctatctt tcttatgaaa ccgttcgagg ggcaggtgga
    32521 ttaccagtgg gaacttctgg taagggcatg ctcatgttgt cagggggaat cgattcccct
    32581 gtagctggct atctagcgct taaacgaggg gtagatatag aggcagttca ctttgccagc
    32641 ccaccttaca cgagtcctgg tgctcttaaa aaagcccaag atttgacccg taaattaacc
    32701 aaatttgggg gaaatatcca gtttatcgaa gttcctttta cagagattca agaggaaatc
    32761 aaagccaaag cgccagaagc ctaccttatg accttgacgc gtcgttttat gatgcgtatt
    32821 actgaccgta ttcgtgaggt acgaaatggt ttagttatca tcaatgggga aagtctaggt
    32881 caagtagcca gccaaaccct tgaaagtatg aaggctatca atgctgttac caacactccc
    32941 atcattcgtc ctgtggttac catggacaag ttggaaatca ttgacatcgc ccaggaaatc
    33001 gatacctttg acatttcaat ccaaccgttt gaagactgtt gtactatttt tgcaccagat
    33061 cgtccaaaaa caaatcctaa aattaagaat gcggagcagt acgaagcgcg tatggatgtt
    33121 gaaggcttgg ttgagcgagc agtggctgga atcatgatta ctgaaatcac acctcaagcc
    33181 gaaaaagatg aagttgatga cttgattgac aatctgctct aattcagaaa atccaaaaga
    33241 atagcgaaaa tcagtaaaaa aagttagttt tttctctaaa aacaggtaaa aaactaactt
    33301 tttttatttt tatgatataa tgatataaaa ttttgaatat agagagtttt ctgacaatga
    33361 atcaatccta cttttatcta aaaatgaaag aacacaaact caaggttcct tatacaggta
    33421 aggagcgccg tgtacgtatt cttcttccta aagattatga gaaagataca gaccgttcct
    33481 atcctgttgt atactttcat gacgggcaaa atgtttttaa tagcaaagag tctttcattg
    33541 gacattcatg gaagattatc ccagctatca aacgaaatcc ggatatcagt cgcatgattg
    33601 tcgttgctat tgacaatgat ggtatgggga ggatgaatga gtatgcggct tggaagttcc
    33661 aagaatctcc tatcccagag cagcagtttg gtggtaaggg tgtggagtat gctgagtttg
    33721 tcatggaggt ggtcaagcct tttatcaagc acaaaacagg ttggtttgat ggcatgatga
    33781 cgacaggttg ctctatggga gcctatcatg cactcaattt cttcctccag catccagatg
    33841 tctttaccaa agtgattgct ctcagtggtg tttacgacgc acgtttcttt gtcggcgatt
    33901 actacaacga tgatgctatt taccaaaact cgccagtaga ttatatttgg aaccaaaacg
    33961 atggctggtt tattgaccgt taccgtcagg cagagattgt gctgtgtacg gggcttggag
    34021 cctgggaaca agatggttta ccatcctttt acaagctcaa agaagccttt gaccagaaac
    34081 aaattccagc ctggtttgct gaatggggac atgatgtcgc ccacgactgg gaatggtggc
    34141 gtaaacaaat gccttatttc ctcggtaatc tctatttata aaaggagtta cctatgaatt
    34201 accttgttat ttctccctac tatccacaaa actttcaaca gtttaccatc gaactagcta
    34261 ataaaggcat cacagtcttg ggaattggtc aagagtctta cgagcaattg gatgagccct
    34321 tgcgcaatag cttgaccgag tattttcgtg ttgataatct tgagaacata gatgaagtca
    34381 aacgtgcagt tgcttttctc ttttataaac atggtccaat tgaccgcatc gagtctcaca
    34441 atgaatactg gcttgagcta gacgcaacac tcagagaaca attcaatgtt tttggtgcca
    34501 aaccagagga tctcaaaaag acgaaatata agtctgaaat gaagaaactt ttcaaaaaag
    34561 caggtgttcc tgtggtacct ggagctgtta tcaagacgga agcagatgtt gatcaagcag
    34621 tgaaagaaat cggtcttcca atgattgcca aacctgataa tggagtggga gcagccgcaa
    34681 cctttaaact tgagacagaa gacgatatca atcacttcaa gcaagaatgg gaccattcaa
    34741 ccctttattt ctttgaaaaa tttgtcactt ccagcgaaat ctgtaccttt gacgggctcg
    34801 tggacaagga tggaaagatt gtcttctcaa caacctttga ctacgcctat acaccgcttg
    34861 acctcatgat ttataagatg gacaattctt attatgtgct caaggatatg gatcctaaac
    34921 tgcgcaagta tggggaagca attgtcaaag aatttggtat gaaagaacgg tttttccata
    34981 ttgagttctt ccgtgagggg gacgattata ttaccatcga gtacaataac cgccctgcag
    35041 gtggttttac cattgatgtt tataactttg ctcattcctt ggacctttat cgtggctatg
    35101 cagctattgt cgcaggagag gagttcccgg cgtcagactt tgaaactcag tattgtttgg
    35161 ctacttctcg ccgtgcaaat gctcactatg tttattcaga agaggatttg cttgccaaat
    35221 atagccagca gttcaaggtt aaaaaagtca tgccagctgc cttcgcggaa cttcaaggag
    35281 attacctgta tatgctgaca actccgagtc gacaagaaat ggatcagatg attgctgatt
    35341 tcggacaacg tcaagaataa gaactatcgg attaaggaaa ttcactccct taatcctttt
    35401 gttttgtctg gtaaaaaata agagcatcct aacaaggtag ctatcataaa acttgttcga
    35461 taactatttg aagcaggatt aggtggctag aaattgaatt ttaacatttc aatttagtca
    35521 tagtattgtg ttttcgtatc cttaaatcag ctaaaaggat ccatgacgac acctatacga
    35581 tatagttttc aggataccaa accagtctat taatactcaa tgaaaatcaa agagcaaact
    35641 aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtggatag aactgacaga
    35701 gtcagtatca tatacctacg gcaaggtgaa gctgacgtgg tttgaagaga ttttcgaaga
    35761 gtataaaata ttcaggtgac gcatagatat agttaattga agctttgttt gaaatctgat
    35821 aaaataatga tattactaag ttttaaaaac taaagaaaag ggaagatatg attacaggcg
    35881 aattaaaaaa taaaatcgat cagctgtggg aaattctttg gacagaagga aacgcaaatc
    35941 ctttaacaaa tattgaacag ttgacttatc tcttatttat gaaagatttg gatagtgtcg
    36001 agcttggacg tgaaagtgat gctgaatttc tagggattcc ttatgaggga gtttttccaa
    36061 aagataaacc tgaataccgt tggtcaactt ttaaaaatat aggagatgct caggaagttt
    36121 atcgtttaat gactcaggag atttttccgt ttattaaaaa tctcaagggg gatacagatg
    36181 atacagcctt ttcacgatat atgcgagaag ctatttttca aataaataaa cctgctacgc
    36241 ttcaaaaggc aatttctatc ttagatgttt ttccaactag gggattagat gtagattttg
    36301 ataatgacaa acaaagtatt actgatatcg gagatatcta tgaatatctg ttatcaaaat
    36361 tgtcgaccgc aggtaaaaat ggacagttcc gtacacctcg tcacatcatc gatatgatgg
    36421 ttgagttgat gcaaccgact atcaaagata tcatctcaga tcccgctatg ggttctgctg
    36481 gcttcttagt atctgctagc cgttacttaa agcgtaagaa agatgaatgg gaaaccaata
    36541 cagataatat caatcatttt cataatcaga tgtttcatgg aaatgatacg gatacgacta
    36601 tgttgagact tggggcgatg aacatgatgc tacatggagt agaaaatcca caaatcagtt
    36661 accttgactc gctgtctcaa gataatgaag aagccgataa atatactttg gttttagcaa
    36721 atcctccttt taagggctca cttgactaca attcaacctc taatgacctt cttgcaaccg
    36781 taaaaaccaa aaaaacagaa ttactctttc tttctctttt cttgcgaact ttaaaaccag
    36841 gtggacgagc agcagttatc gtacctgatg gtgtcctttt tggttcgtct aaagctcata
    36901 aaggaattcg tcaggaaatt gtagagaatc ataagcttga tgctgtaatc tcaatgccta
    36961 gtggtgtgtt caagccttat gctggagttt caactgccat tctcatcttt acaaaaactg
    37021 gtaatggtgg tactgacaaa gtctggtttt acgatatgaa agcggatggt ttaagtttgg
    37081 atgataagcg acaaccgatt agcgacaatg atattccaga tattatcgaa cgctttcatc
    37141 atcttgaaaa agaagcagaa cgtcagagaa cggatcaatc tttctttgtt ccagttgctg
    37201 agataaagga aaatgattat gatttgtcta tcaataaata taaagagatt gagtatgaaa
    37261 aagttgagta tgaaccaaca gaggtcatct taaagaaaat caatgattta gaaaaagaaa
    37321 ttcaagctgg cttggctgaa ttagaaaaat tactcaagta gggaggtggc tgtatgaaaa
    37381 aagtgaagtt gggggaagtc ttatctctaa aaaaaggcaa gaaagccact gtacttgctg
    37441 aacaaacaac tctaagccaa cgttatattc aaatagatga tttaagaaat aataataatt
    37501 taaaattcac tgaaagttta aatatgactg aagcactccc agatgatatt ctgatagcat
    37561 gggatggagc taatgcagga acagttggtt atggattatc gggagctgtt ggtagtacaa
    37621 ttacggtctt aaaaaagaat gagcgataca aagaaaaaat tatatcagat tacttgggag
    37681 tctttttgga aagtaaatcg cagtatttac gagaacattc aacaggtgca acaattcctc
    37741 atttaaacaa gaatatatta cttgatttac aattagaatt gctaggtatc gaagaacaag
    37801 agaacattat ctgtattctt aatacgatta aagggcttat tactaaaaga aaattgcagt
    37861 tagatgaact aaacttgctc g
//
LOCUS       DAVBOM010000017        37297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBOM010000017 DAVBOM010000000
VERSION     DAVBOM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.017"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..567
                     /locus_tag="VQ878_000900"
     CDS             <1..567
                     /locus_tag="VQ878_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET3095254.1"
                     /translation="DAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRA
                     NGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVT
                     PMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQT
                     SMASIGLLGLALAGLLGGLGLKNKKEEN"
     gene            734..1432
                     /locus_tag="VQ878_000901"
     CDS             734..1432
                     /locus_tag="VQ878_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3095255.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1429..2481
                     /locus_tag="VQ878_000902"
     CDS             1429..2481
                     /locus_tag="VQ878_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3095256.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2676..3287
                     /gene="rpsD"
                     /locus_tag="VQ878_000903"
     CDS             2676..3287
                     /gene="rpsD"
                     /locus_tag="VQ878_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET3095257.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3472..3627
                     /locus_tag="VQ878_000904"
                     /pseudo
     CDS             3472..3627
                     /locus_tag="VQ878_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            4054..4314
                     /locus_tag="VQ878_000905"
     CDS             4054..4314
                     /locus_tag="VQ878_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095258.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            4268..4488
                     /locus_tag="VQ878_000906"
                     /pseudo
     CDS             4268..4488
                     /locus_tag="VQ878_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4807..5736
                     /locus_tag="VQ878_000907"
     CDS             4807..5736
                     /locus_tag="VQ878_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3095259.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5750..6673
                     /locus_tag="VQ878_000908"
     CDS             5750..6673
                     /locus_tag="VQ878_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3095260.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6757..8232
                     /locus_tag="VQ878_000909"
     CDS             6757..8232
                     /locus_tag="VQ878_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET3095261.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8504..9490
                     /locus_tag="VQ878_000910"
     CDS             8504..9490
                     /locus_tag="VQ878_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET3095262.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9612..10472
                     /locus_tag="VQ878_000911"
     CDS             9612..10472
                     /locus_tag="VQ878_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET3095263.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(10649..11713)
                     /locus_tag="VQ878_000912"
     CDS             complement(10649..11713)
                     /locus_tag="VQ878_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095264.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11776..12687)
                     /locus_tag="VQ878_000913"
     CDS             complement(11776..12687)
                     /locus_tag="VQ878_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET3095265.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILNQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12680..13273)
                     /locus_tag="VQ878_000914"
     CDS             complement(12680..13273)
                     /locus_tag="VQ878_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET3095266.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            complement(13260..13586)
                     /locus_tag="VQ878_000915"
     CDS             complement(13260..13586)
                     /locus_tag="VQ878_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3095267.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13725..14891)
                     /locus_tag="VQ878_000916"
     CDS             complement(13725..14891)
                     /locus_tag="VQ878_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET3095268.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            14949..16088
                     /locus_tag="VQ878_000917"
     CDS             14949..16088
                     /locus_tag="VQ878_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3095269.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            16156..18006
                     /locus_tag="VQ878_000918"
     CDS             16156..18006
                     /locus_tag="VQ878_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3095270.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSAFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(18309..18941)
                     /locus_tag="VQ878_000919"
     CDS             complement(18309..18941)
                     /locus_tag="VQ878_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3095271.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18963..19835)
                     /gene="sdaAA"
                     /locus_tag="VQ878_000920"
     CDS             complement(18963..19835)
                     /gene="sdaAA"
                     /locus_tag="VQ878_000920"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET3095272.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19844..20515)
                     /gene="sdaAB"
                     /locus_tag="VQ878_000921"
     CDS             complement(19844..20515)
                     /gene="sdaAB"
                     /locus_tag="VQ878_000921"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET3095273.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20757..21329
                     /locus_tag="VQ878_000922"
     CDS             20757..21329
                     /locus_tag="VQ878_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3095274.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21381..21701)
                     /locus_tag="VQ878_000923"
     CDS             complement(21381..21701)
                     /locus_tag="VQ878_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3095275.1"
                     /translation="MQRLEVYKNYQHLYDLQIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            22126..22410
                     /locus_tag="VQ878_000924"
     CDS             22126..22410
                     /locus_tag="VQ878_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3095276.1"
                     /translation="MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFG
                     YSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            22465..24573
                     /locus_tag="VQ878_000925"
     CDS             22465..24573
                     /locus_tag="VQ878_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3095277.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     VLASRMEKRSLVELLKGGIL"
     gene            24570..25211
                     /locus_tag="VQ878_000926"
     CDS             24570..25211
                     /locus_tag="VQ878_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095278.1"
                     /translation="MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            25418..26224
                     /locus_tag="VQ878_000927"
     CDS             25418..26224
                     /locus_tag="VQ878_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3095279.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            26190..26660
                     /locus_tag="VQ878_000928"
     CDS             26190..26660
                     /locus_tag="VQ878_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET3095280.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(26950..27270)
                     /locus_tag="VQ878_000929"
     CDS             complement(26950..27270)
                     /locus_tag="VQ878_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3095281.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            28034..28414
                     /locus_tag="VQ878_000930"
     CDS             28034..28414
                     /locus_tag="VQ878_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET3095282.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            28788..29846
                     /locus_tag="VQ878_000931"
     CDS             28788..29846
                     /locus_tag="VQ878_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095283.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILIFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKR"
     gene            30161..31137
                     /locus_tag="VQ878_000932"
                     /pseudo
     CDS             30161..31137
                     /locus_tag="VQ878_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            31514..31888
                     /locus_tag="VQ878_000933"
     CDS             31514..31888
                     /locus_tag="VQ878_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET3095284.1"
                     /translation="MELVLPNNYVALEQEEMMYFDGGFSIPRWPVATAINIAFNDVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            32096..32998
                     /locus_tag="VQ878_000934"
     CDS             32096..32998
                     /locus_tag="VQ878_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095285.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            33054..33407
                     /locus_tag="VQ878_000935"
     CDS             33054..33407
                     /locus_tag="VQ878_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET3095286.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGEAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVK"
     gene            33404..34132
                     /locus_tag="VQ878_000936"
     CDS             33404..34132
                     /locus_tag="VQ878_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095287.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            35264..35503
                     /locus_tag="VQ878_000937"
     CDS             35264..35503
                     /locus_tag="VQ878_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095288.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            36053..>37297
                     /locus_tag="VQ878_000938"
     CDS             36053..>37297
                     /locus_tag="VQ878_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET3095289.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKRDAENAKKALEEAKRAQKKYEDDQKKTEEKAKKEKEASKEEQAANLKYQQEL
                     VKYASEKDSVKKAKILKEVEEAEKEHKKKRAEFEKVRSEVIPSAEELKKTRQKAEEAK
                     AKEAELIKKVEEAEKKVTEAKQKLDAERAKEVALQAKIAELENEVYRLETELKGIDES
                     DSEDYVKEGLRAPLQSELDAKRTKLSTLEELSDKIDELDAEIAKLEKNVEYFKKTDAE
                     QTEQYLAAAEKDLADKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAP
                     KTGWKQENGMWYFYNTDGSMATG"
BASE COUNT        11696 a         6296 c         7788 g        11517 t
ORIGIN      
        1 gacgctaaaa acccagccct atctccacta ggcgaaaacg tgaagaccaa aggtcaatac
       61 ttctatcaag tagccttgga cggaaatgta gctggcaaag aaaaacaagc gctcattgac
      121 cagttccgag caaacggcac tcaaacttac agcgctacag tcaatgtcta tggtaacaaa
      181 gacggtaaac cagacttgga caacatcgta gcaactaaaa aagtcactat taagataaat
      241 gttaaagaaa catcagacac agcaaatggt tcattatcac cttctaactc tggttctggc
      301 gtgactccga tgaatcacaa tcatgctaca ggtactacag atagcatgcc tgctgacacc
      361 atgacaagtt ctaccaacac gatggcaggt gaaaacatgg ctgcttctgc taacaagatg
      421 tctgatacga tgatgtcaga ggataaagct atgctaccaa atactggtga gactcaaaca
      481 tcaatggcaa gtattggttt acttgggctt gcgcttgcag gtttactcgg tggtctaggt
      541 ttgaaaaaca aaaaagaaga aaactaatca gctaaggaaa taaatgatgg atagtgggct
      601 gactaagatt agtttaacaa ctcaatcagc aatcaggact ttctttcaat agcagattaa
      661 aatcatcgta aaacaataaa aatagtgtta tacttaaagc agtatagcac tgtttttatc
      721 aaaggagaga cagatgggaa agacaatttt actcgttgac gacgaggtag aaatcacaga
      781 tattcatcag agatacttaa ttcaggcagg ttatcaggtc ttggtagccc atgatggact
      841 ggaagcgcta gagctgttca agaaaaaacc gattgatttg attatcacag atgtcatgat
      901 gcctcggatg gatggttatg atttaatcag tgaggttcaa tacttatcac cagagcagcc
      961 tttcctattt attactgcta agaccagtga acaggacaag atttacggcc tgagcttggg
     1021 agcagatgat tttattgcta agccttttag cccacgtgaa ctggttttgc gtgtccacaa
     1081 tattttgcgc cgccttcatc gtgggggcga aacagagctg atttcccttg gcaatctaaa
     1141 aatgaatcat agtagtcatg aagttcaaat aggagaagaa atgctggatt taactgttaa
     1201 atcatttgaa ttactgtgga ttttagctag caatccagag cgagttttct ccaagacaga
     1261 cctctatgaa aagatctgga aagaagacta cgtggatgac accaatacct tgaatgtgca
     1321 tatccatgct cttcgacagg agctggcaaa atatagtagt gaccaaacgc ccactattaa
     1381 gacagtttgg gggttgggat ataagataga gaaaccgaga ggacaaacat gaaactaaaa
     1441 agttatattt tggttggata tattatttca accctcttaa ccattttggt tgttttttgg
     1501 gctgttcaaa aaatgctgat tgcgaaaggc gagatttact ttttgcttgg gatgaccatc
     1561 gttgccagcc ttgtcggtgc tgggattagt ctctttctcc tattgccagt ctttacgtcg
     1621 ttgggcaaac tcaaggagca tgccaagcgg gtagcggcca aggattttcc ttcaaatttg
     1681 gaggttcaag gtcctgtaga atttcagcaa ttagggcaaa cttttaatga gatgtcccat
     1741 gatttgcagg taagctttga ttccttggaa gaaagcgaac gagaaaaggg cttgatgatt
     1801 gctcagttgt cgcatgatat taagactcct atcacttcga tccaagcgac ggtagaaggg
     1861 attttggatg ggattatcaa ggagtcggag caagctcatt atctagcaac cattggacgc
     1921 cagacggaga ggctcaataa actggttgag gagttgaatt ttttgaccct aaacacagct
     1981 agaaatcagg tggaaactac cagtaaagac agtatttttc tggacaagct cttaattgag
     2041 tgcatgagtg aatttcagtt tttgattgag caggagagaa gagatgtcca cttgcaggta
     2101 atcccagagt ctgcccggat tgagggagat tatgctaagc tttctcgtat cttggtgaat
     2161 ctggtcgata acgcttttaa atattctgct ccaggaacca agctggaagt ggtggctaag
     2221 ctggagaagg accagctttc aatcagtgtg accgatgaag ggcagggcat tgccccagag
     2281 gatttggaaa atattttcaa acgcctttat cgtgtcgaaa cttcgcgtaa catgaagaca
     2341 ggtggtcatg gattaggact tgcgattgcg cgtgaattgg cccatcaatt gggtggggaa
     2401 atcacagtca gcagccagta cggtctagga agtaccttta ccctcgttct caacctctct
     2461 ggtagtgaaa ataaagccta aaaccccttt acaaatccag ctattcatgg tagaatggat
     2521 tttgtgtgaa atatcagcag gaaagcatga agctcgtcaa caggtgtctt atgataagta
     2581 accttggctg tttaggcgaa gggcatctgc acgaatcagg gctttctaag tgactatttc
     2641 caccgaaata ttatttatat caggaggaca ttcatatgtc acgttataca ggaccatctt
     2701 ggaaacaagc tcgtcgcctt ggcctttcac ttacaggtac aggtaaagaa ttggcacgtc
     2761 gtaactacgt accaggacaa cacggaccaa acaaccgttc taaattgtca gaatacggtt
     2821 tgcaattggc tgaaaaacaa aaacttcgtt tcacttacgg tgtaggtgaa aaacaattcc
     2881 gtaacttgtt cgtacaagct acaaaaatca aaggtggaat cctaggtttc aactttatgc
     2941 ttcttttgga acgtcgtttg gataatgttg tttaccgtct tggtctcgcg actactcgtc
     3001 gtcaagctcg tcaattcgta aaccacggtc acatccttgt tgacgggaaa cgcgttgata
     3061 tcccatcata ccgcgtaact ccaggtcaag tgatctcagt tcgtgaaaaa tcattgaaag
     3121 ttccagcaat ccttgaagca gtagaagcta ctcttggacg tccagcattc gtatcattcg
     3181 acgctgaaaa gttggaaggt tcattgactc gcttgccaga acgcgacgaa atcaacccag
     3241 aaatcaacga agcacttgtc gttgaattct acaacaagat gttgtaatat tttattgaat
     3301 aagacaggct ttgaggcctt gatattaagc actttgggac gttctccctt agtgcttttt
     3361 tgatttctct tagtatccag ctataatcgt tgagacataa ctagaccgat atagtccaaa
     3421 gtgatatagt aaaatgaacc aaaaatagta cacaatgtgg tataatcttt tatggcatat
     3481 tcaatagatt ttcgtaaaaa agttctctct tattgtgagc gaacaggtag tataacagaa
     3541 gcatcacacg ttttccaaat ctcacgtaat accatttatg gctggttaaa gctaaaagag
     3601 aaaacaggag agctaaacca ccaagtatag tgtattgaat ttataacagt acaccttggc
     3661 tgctaaaata tttctataaa ttaatttgac tttcctgata gagttgttca catcttattt
     3721 caaatcacta taaaagctct ataatctctt tattaagatt tgcccatcag acgaaatata
     3781 atggattgaa actagaatag tacacatcta cttctaaaac attgttagaa atcgatttga
     3841 ctgtcctgat cgatttgtcc tgttcttgtt tcattttact atagaacgat ttgaaggcgt
     3901 ttatgatatt tagctgtacg agagtctttt aaaagtgttt tgatagtttg gatttcttct
     3961 ttagttgatt tcatatcact gttatataat gctttttgat tttagtctag tattagtaag
     4021 cagactcaaa ccttagaaaa tcttttgaga tcattgacag gtgtatcgaa tcctaccaca
     4081 gattcagcac gtctggtttt ggcagaggct aagaaagctt ttgcagatga tagtttgaca
     4141 gagcaaggtt tacgtgatat tttgcaaaca gtcaaagatg ccattgcttc cctagagtcc
     4201 attaaggaaa gccagtcagc aactaaggat ggaggacaaa cagcgggcaa agaaacagca
     4261 ggagaagatg agtctgcaaa tcaaactcaa gaaattagcc aaggaattaa gtaaacttct
     4321 taaagactca aaccttgaaa cagtagataa ggatgtcctt gaaaactctc aaaaagaact
     4381 tcaaaaagca gttttgttct tggcagatga aaaagctctg agcatactga agcagaggtg
     4441 attgataatc ttaaagaggt tattgctaag ttgaaagcaa acgcctaata acatattaaa
     4501 aatctccaga ttaggaacta tctctgagtt ccctagtctg gagatttttc agtatacccc
     4561 gttgttggat gcttataaca gagtgacgcc atcactgggc taatagagat aaaataaaca
     4621 attgatttag gacatttgtt tgatagtggt gataaagttt taaatctgct acataatttg
     4681 tggagttttt tctataatta ggagtttaac ctaacctgca aataggagta tactaataat
     4741 gtaatcgtta tcaaaagtct aaaaaagaat ttttagatgg atatcaaaat aaaaagggag
     4801 gaaattatga aaaagttttc aaaaacattg agagacaact ggatctttct cttgatggtt
     4861 ttgccaggga cactctggtt gattctattc ttttacattc cagtatttgg gaacgtggtt
     4921 gccttcaaag actaccacat gaccagtaat ggtttcatag atagtatcat aaatagtaaa
     4981 tgggtcggac tcgataattt cagattctta tttagttcaa gagacgcctt tattatcaca
     5041 cgaaatactg tcctctacaa tcttggcttt atctttctag gtttagttgt atctgtaggg
     5101 attgccatta tcctcagcga gctccgttct aagagaatgg tgaagatttt ccaaacttct
     5161 atgttgttcc cttacttctt gtcttgggtt atcatcagtt tctttacaga tgccttccta
     5221 aatattgata aaggggtgtt caatcatcta ttggaaagtc ttggtctcaa agaagtcaat
     5281 ttttacgctg acctgggcat ctggccctat ctcctacttt tcctaggtat ttggaaaggc
     5341 tttggatata gcagtgtcat gtactatgcg acgatcatgg gaattgatcc aacctactac
     5401 gaagcagcga cagtggacgg agctagcaag tggcaacgta ttcgcaacgt aaccattcct
     5461 cagttgactc cgcttgtaac tgtattgacc atccttgcag tcggaaatat cttccgcgca
     5521 gactttggtc tcttctatca aatcccacac aatgctggtc agctttacaa tgtaaccaac
     5581 gttttggacg tatatgtctt taatggtttg actcagacag cagatatcgg tatggctgca
     5641 gcagccggtc tttaccaatc cgttgttggt ttgattctgg ttatcctatc aaacttgctt
     5701 gcaagacgag tcgatccaaa ctcagctttg ttctagaaag gaggagaata tggcaaaaaa
     5761 gaaaattaaa aaagaaaaaa ttgataatgt cggcattcac tccttcagta agaaagcaga
     5821 tatcttcttc agtatcattt cgggtttgat tgccctctct tgtatcctac cttttgtatt
     5881 cgttatcatt atttcagtga cagacgagaa aagcctcctc caatacggct atagcttctt
     5941 cccatcccaa tttggcttag acggttttga gtttttggca cagtttaagg ataaaatcct
     6001 acaagccctc ttcatctctg tctttgtaac cgtagttggg acattgacaa atgtctttat
     6061 cacaacaacc tatgcctacg ctatttcacg gacaaccttt aagtatcgca gattttttac
     6121 catcttcgtc cttctcagta tgttgttcaa cgctggtttg gtaccaggtt atatcatggt
     6181 gacccgtgta cttcagcttg gtgacactgt ttgggccttg attgttccaa tgcttctctc
     6241 accattcaat atcatcttga tgcgttcctt cttcaagaag accattccag aagccattct
     6301 cgaatcggct cgtatcgatg gtgccagtga ggcccggatt ttcttccaaa tctgtttgcc
     6361 attgtcacta ccaggtatcg caaccatcac gcttttgaca gctcttggtt tctggaatga
     6421 ctggttcaac gcccttcttt acatcaagag tgataacttg tatccattgc aatatttgct
     6481 catgcaaatc caacaaaata tggactacat tgccaaagcg gtcggcttga ctggtcaact
     6541 gggagttgct ctaccgaaag aaacaggtcg tatggccatg gttgtggtag caacccttcc
     6601 aatcgcgatt ttgtatccat tcttccaacg ctactttgta aaaggtttga ctatcggtgg
     6661 tgtgaaagaa tagcacttgt ttccaaactt cccttgcgtg aagttaagat cattacattg
     6721 tttataagtt taaaaataaa aaaaggagtt tttatcatga aaaactggaa aaaatatgct
     6781 tttgcatctg ctagtgtagt tgctttggct gcaggtcttg ctgcttgtgg caacttgaca
     6841 ggtaacagca aaaaagctgc tgattcaggt gacaaacctg ttatcaaaat gtaccaaatc
     6901 ggtgacaaac cagataactt ggatgaattg ttagcaaatg ccaacaaaat catcgaagaa
     6961 aaagttggtg ctaaattgga tatccaatac cttggctggg gtgactatgg taagaaaatg
     7021 tcagttatca catcatctgg tgaaaactat gatatcgcct ttgcagataa ctatattgta
     7081 aatgctcaaa aaggtgctta tgctgacttg acagaattgt acaaaaaaga aggtaaagac
     7141 ctttacaagg cacttgatcc agcttatatc aagggtaata ctgtaaatgg taagatttac
     7201 gctgtaccag ttgcagccaa cgtagcatca tctcaaaact ttgccttcaa cggaactctc
     7261 cttgccaaat atggtatcga tatttcaggt gttacttctt acgaaactct tgagccagtc
     7321 ttgaaacaaa tcaaagaaaa agctccagac gtagtaccat ttgctattgg taaagttttc
     7381 atcccatctg ataactttga ctacccagta gcaaacggtc ttccattcgt tattgacctt
     7441 gaaggcgata ctactaaagt tgtaaaccgt tacgaagtac ctcgtttcaa agaacacttg
     7501 aagactcttc acaaattcta tgaagctggc tacattccaa aagacgtcgc aacaagcgat
     7561 acttcctttg accttcaaca agatacttgg ttcgttcgtg aagaaacagt aggaccagct
     7621 gactacggta acagcttgct ttcacgtgtt gccaacaaag atatccaaat caaaccaatt
     7681 actaacttca tcaagaaaaa ccaaacaaca caagttgcta actttgtcat ctcaaacaac
     7741 tctaagaaca aagaaaaatc aatggaaatc ttgaacctct tgaatacgaa tccagaactc
     7801 ttgaacggtc ttgtttacgg tccagaaggc aagaactggg aaaaaattga aggtaaagaa
     7861 aaccgtgttc gcgttcttga tggctacaaa ggaaacactc acatgggtgg atggaacact
     7921 ggtaacaact ggatccttta catcaacgaa aacgttacag accaacaaat cgaaaattct
     7981 aagaaagaat tggcagaagc taaagaatct ccagcgcttg gatttatctt caatactgac
     8041 aatgtgaaat ctgaaatctc agctattgct aacacaatgc aacaatttga tacagctatc
     8101 aacactggta ctgtagaccc agataaagcg attccagaat tgatggaaaa attgaaatct
     8161 gaaggtgcct acgaaaaagt attgaacgaa atgcaaaaac aatacgatga attcttgaaa
     8221 aacaaaaaat aatcagctaa attgatttcg tgtattcatt cctaactcct aaaataagaa
     8281 tcactgcttt cctcaggttg gtctggggga gacagtggtt tttttggcac aaggatatag
     8341 atatccatgt tttctcttgt ccttatttta accattcagg aaatttcgag aaccctctac
     8401 aatttccagt caaataaatt gcattcgttt tctcaagcag gtatactagt gtagataaat
     8461 aaaaaattta gaaaatttaa gaatagaaaa gagaacaaat cttatggcaa aagatattcg
     8521 tgtcttactt tactaccttt atactccaat tgaaaatgca gagcaatttg ctgcagacca
     8581 cttggctttc tgtaaatcaa tcggtcttaa aggccgtatc ctagtcgctg acgagggaat
     8641 taacggaaca gtttcaggtg actatgaaac aactcaaaaa tacatggact acgttcacag
     8701 ccttccagga atggaagaac tctggttcaa gattgacgaa gaaagtgaac aagccttcaa
     8761 gaagatgttt gttcgctaca agaaagaaat tgtccacctt ggtttggaag acaacgactt
     8821 tgacaatgac atcaacccac ttgaaacaac aggtgcttac ttgtctccaa aagagttcaa
     8881 agaagcgctt cttgataaag ataccgttgt ccttgacaca cgtaatgatt atgagtatga
     8941 cctaggacat ttccgtgggg ctattcgccc agatattcgc aacttccgtg agttaccaca
     9001 atgggtccgt gataacaagg aaaaattcat ggacaagcgt gtcgtggttt actgtacagg
     9061 tggcgttcgc tgtgagaaat tctcaggctg gatggttcgt gaaggttaca aagatgtcgg
     9121 ccaattgcac ggaggaatcg caacttacgg taaagaccca gaagttcaag gtgagctttg
     9181 ggatgggaaa atgtacgtct ttgacgagcg tattgccgtt gatgtcaacc atgtcaaccc
     9241 aactatcgta gggaaagact ggtttgatgg aacaccatgt gaacgttatg tcaactgtgg
     9301 aaatccattc tgtaaccgtc gtatcttgac atcagaagaa aatgaagaca agtaccttcg
     9361 tggatgctca cacgagtgcc gtgttcaccc acgtaaccgc tatgtttcaa aaaatgaatt
     9421 gacacaagct gaagtgattg agcgcctagc cgctatcggt gaaagcttgg atcaagcagc
     9481 tactgtataa gatcaaacag tcctcagggg ctgtttttct atgctttgta ctcaaaaatc
     9541 taaagtttgt ttctgtatct ttcagaaaaa taaggtatac tgtatgtaaa cgatttcaaa
     9601 ggagtccagt tatggcaaaa acatttttta ttccaaataa acagagcatt ttaggagaac
     9661 aagagatttt gaatgccaag tcgatcttgg ccttgctaga cggtttggag tcacatagct
     9721 atgatgtagt ctatctccgt cagcctctta atcgtctcga gtatattgag tgtgcgatag
     9781 tggggcaatc acaatttctt tttaaggtca gttatgctga tggtcaaaag gcttaccgtg
     9841 tcgatcttcc tgacctacta acaaagacag actggcagat tatcaagtca tttttagatg
     9901 ctttgcttgc ttatacaggg actgatattg aagggctaga tggttttgat tttgaagctt
     9961 atttccaagc aagtattcaa gcctatctag cagaccctgt agctcgtttt acgatttgcc
    10021 aaggaatttt taatcctatt ttctttagtc gtgagaactt gaaaagcttt ttagaggcag
    10081 atggcttggc tcagtttgaa gcgcgtgtgc gtgcggttca agagacagat gcctactttg
    10141 cgagagtttc cttctatcag gatggagaag gaaaagtgca tggcgtttac catctagctc
    10201 aaggagtcaa gacagtttta ccgagagaac cgtttgttcc tgcagcctat attgagcaat
    10261 tggtggataa ggaagtgcag tgggagattg acttggttca aatcacagga gatggctcta
    10321 aaccagaaga ctatgaagcc attgcccgct tggactatgc aaaattctta gaggtattac
    10381 ccctatcttt ttaccaccaa ctagacgcca atcaaataga agtgcaaccc atattagaca
    10441 aagattttaa agcattagca caagaagagt aaagcagaag caggtcaatc gacttgcttt
    10501 tttgaaatag aaaaatcctg ccatgaaaga caggattgct actcaatgaa aatcaaagag
    10561 caaactagga agctagccgc aggctgtact tgagtacggt aaggcgaagc tgacgtggtt
    10621 tgaatttgat tttcgaagag tatgaagttt aaagaaaggc caagatacga agataatctc
    10681 caatcagtgc cacttcagct acaaagaaga ggaggataat aactccgttc acaaggacag
    10741 acaagaataa ttgatagaag gagtcggttt cacttgcttg acttggtctt gtaatgatat
    10801 ggagactggc aagcagaatg attccaatgc taatcacaca caagagggct gtaaatcgta
    10861 ggctatcaaa gaaagcaaag aaactagcaa tagcagtgag gaagattgga attgctaaga
    10921 gttgactata ttgttggaga accttgtcta gcgtccagtc cttttcctgg tggataaatc
    10981 gtctcacaac gaaactaccc aagaggaatg aaaagaagaa gagtgttgtc gctactagga
    11041 tagagatgat agaaaaaaga gttaaaggag ctagctgctc agggaagcga ctgttaatgc
    11101 ttgctatatg tccatagtaa gcatgtttga tgtgatagat actaaagaaa aaggaagatg
    11161 cagaaaacag aatgagcaag agaaaggctg tgtaactgtg tgtgatactt gtttccaact
    11221 tacttgtagg agatttgatc gcttccacta gccaagacca aaaatcaagc acttgctctt
    11281 tccatttatc cctagatttt ggagcttggt cggggatata aggactttct aaagatttac
    11341 tgataagaag tggctctttc gtggttgctt tttgctgagg aagagcttct tggctctctt
    11401 cagctatagt gactttttct gtttctttag aaaggtctgg ctcttcttca gtagaattag
    11461 atgccttctt ttcttctatt tctgttctcg cttcactgtc ttcaggagct tcaattttct
    11521 cttcttgctg gctttccaat tcgacttcag cttgagggac ttcctcctct aactgagtat
    11581 ttttttcaat tggtgtatcg agatcggcta tcgtttcttc agccttgtct gcaacctctt
    11641 gagcttgctc ttcaggcttg ttcttgcttg ttgtttttac aaaatcatta ctttcaaacc
    11701 attcttgttt catggtagaa cctccttttt agttagataa atatgcttcc atagtagcag
    11761 atgtaagcgt ttttgtcaac gtctgcttgg tgtggatatt agatcaatat tatcatcaga
    11821 tctcgcaatg agttgatcct tgacatcggt tttttcagtt ttgtaagggt tgcttaattc
    11881 cgtacctctt gattcaggct tttctcttgt gaattggaag atagaaccat agttgcttga
    11941 gatgtcccag ttaattcgtt ggctttcttt ctggtttagg atgattctga gataatcttt
    12001 ggcagtcagt tcaaccttgc catggacttg gatattttca gcgtggaagt gattctctgt
    12061 tgactctagc tgactatctg taagaactgt atcaaagata ttaacgatat tgggcgttgt
    12121 gagtttactg tttttgatac gacttccttc aattcggagg atatagctgt ttgtattgag
    12181 ggtcgcattt tcaaggctag catttatgat ggtggtttgt ccgcgattgg ctgagatgtt
    12241 gatccctttt agagttctcc cttttggtag ctggagaata acttcttcaa aacgactaga
    12301 gtagctactt gcgatatgaa gaatcccacc aattccagaa gagagaaacg gagtttcaga
    12361 cagtttctta tcagtgagac tcagagttct atcgttctga ttggtgataa gatcatggtg
    12421 agcagaaaga gatggatggt aagaaatgtg gatttgatca tcgaaagagt ctgtgatggt
    12481 gagcgcgtgt tggtggagag taatttctag gttttcgact tccttgccaa aggttagctt
    12541 ttccgtacgg ctatcataga taggttcttt ggacatggaa agtaggcttt taatcccgtc
    12601 agattggata cctacaaaaa gaaggataaa gccgataacg gtagtcacca caccaaagat
    12661 gagaaatcct tttgtccatt tacgcatgct ggttacctct ctttcttttt ttaagaacaa
    12721 attgtaccag gcgaacaatg agtagaccga agaagcgagc tacataggaa atgcctagta
    12781 aaactagcga agaagcaccg atagccagta aaccagaacc aaaaatcaag ataaaggctg
    12841 atttggcttg ggcgaggaca gtgaaacttt caactaaaaa taggaatccg ccgatgatac
    12901 ccagtatgga aactgcaaag aaagccagaa tgacagtcaa agcggctaca aggattgcga
    12961 acagggtcac gaggatggcg attcccagag gaatgccgat aggtgctgca aggagggcta
    13021 acaaggcgat atgtaaaatt tgtcggttat ttttttgagc gggtgcttca ttgatttttt
    13081 tatcgagaag attggataga acttcgtggg ccgcttcttt gggagttccc aaactagcga
    13141 tgagttcttc ttctccttcg actccagcat cgtcaaagag ctctctgaaa tagtccatgg
    13201 cttcgatacg gtcagcttca ggtagtttct tgagatagag ttctagctga gtcaggtatt
    13261 cagttcttgt catggcggat actcccttct atgatgccat tgatggtgtc tgtatagagt
    13321 gcccattcat cttttagggt caagagctgc tctataccac cgtttgtcaa ggagtagtat
    13381 ttgcgcatgc gaccttggaa ctctctagaa taggttgtca gaaagctatt gccttccaat
    13441 tttttgagaa tgggatagag tgtggattct ttgatattag cgatcagctt aatggtttgg
    13501 ctaatctcat aaccataaga atcaccctgc tccagtacgg ccaagatgag aaattcaatc
    13561 aaggcagagg atgttggaaa gtacatggga aacctccttt tctaatgtgt aagattttta
    13621 tatataattt ttctacacat acattgtaca tctaaaagaa agccctgtca agagaaatgt
    13681 gtaaaatttt tatatataaa aaacttctag ctaaaactag aagtttaaag gatcttatcc
    13741 gctctgtcca ctgtaaagag ggccacagtc atcaggatat cgatgagcaa gagggcagct
    13801 acagctggta cccaagagtg gaataggtca aaactgtaac caaagagggt tggcccaaag
    13861 gctgctagga tatagcctcc tgtttgagat aggccggaca attgggctgt cttttcaggg
    13921 gcgcttgtct tgagtgaaaa gttgaccatg agataaggga agagggcgct ggttgcggtt
    13981 ccgatgagga gatggatggc aagccagtaa atgaaattat tgattgggaa aaagagcatg
    14041 gaaatgccga ccacaccagc tagtgaaacc agagtgagca tgagctgacg gttgcgagta
    14101 gataaactgg ttgtcaggct tgggatggtc attgaaaaag gaatgctaat cagagataag
    14161 atagaagtca gcaagccagc ttcgtgactg gatagacctg catggataga catggtaggt
    14221 aaccaggtca tggcggtgta aaagatcaag gattgaaaac ctgaaaagat aataattgcc
    14281 caaacctgtt tattacgcat gacctttatt tgactttttt gtttggtttg tggagctagt
    14341 ctatgattat agcggtgatt tgggagccag accaaaaaag ttgctagaca gagtaacgtg
    14401 aggaggagga taagtccttt ccaagaactg gcttgtgtaa tgggcacagc tagataggaa
    14461 gccagagccg ttgcaatccc catagacgtt acatataagg tggtcagaaa accaattttc
    14521 tttggttgat tggcttggat aagactagga agcaggacat tgatgactgc gacacttgcc
    14581 ccaaccatca aggttcctag atagagcagg ggcagattga ttagtcgaat aagtgagccg
    14641 atggtcaaga agaagaggct gtaggtgaag agatgctcca agccgatttt ctgagccagt
    14701 cgggtagaaa atggtgaaaa gagggtaaac ataaggagag gcaggctggt caagacacca
    14761 agcgaactaa cttctacctc cagaccttgc gaaatatttc ccaaaataat gggtaaaaca
    14821 gtaaaaggag ttcgcaagga aacaccaatc aggataatac ctggaacaaa aaagagtgat
    14881 tgctttttca tataatatct cttctagctg attttaataa cagcttattt taaggctttt
    14941 tcactataat gtcaagtaag gtttctggct ttcaagataa aaatggaaaa gtcttgaaaa
    15001 ttatgataga atggtggaag ggaaaattca ggagagtagt agtgactcaa aatgttgaaa
    15061 gtcttctcgt atccattgta atcagtgcat acaatgaaga aaaatatctg cctggtctaa
    15121 ttgaagactt aaaaaatcaa acctatccta aagagaatat tgaaattcta tttataaatg
    15181 ctatgtccac agatgggacc acagctatca ttcagcaatt tataaaagaa gatgcagagt
    15241 ttaactcaat tagattgtat aacaatccta agaaaaatca agctagtggt tttaacctgg
    15301 gagttaagca ttctgtaggg ggccttattt taaaaattga tgctcattca aaagttactg
    15361 agagttttgt aatgaacaat gtggctgtta ttcaacaagg tgaatttgtc tgtggagggc
    15421 ctagaccgac gattgtcaaa ggaaaaggaa aatgggcaga gaccttgcat cttgttgagg
    15481 aaaatatgtt tggcagtagc attgccaatt atcgaaatag ttccgaggat agatatgttt
    15541 cttctatttt tcatgggatg tataaacgag aggttttcca gaaggttggt ttagtaaatg
    15601 agcaacttgg ccgaactgaa gataatgata ttcattatag aattcgagaa catggttata
    15661 aaatccgcta tagcccaagt attctatctt atcagtatat tcgaccaaca ttcaagaaaa
    15721 tgctgcatca aaagtattca aatggtttgt ggattggctt gacaagtcat gttcagttta
    15781 agtgtttatc attatttcat tatgttcctt gtttatttgt tttgagtctt gtgtttagtc
    15841 tagcattgtt accgatcaca ttcgtattca taactttact attaggtgcc tattttctac
    15901 ttttatcatt actgtcatta ctcactttgc tgactttatt aaaacataaa aatggatttc
    15961 taattgtgat gccctttctt ttattttcca ttcactttgc ttatggcctt gggacgattg
    16021 taggtttaat tagaggattt aaatggaaga aggagtacaa gggaacagta atttatttgg
    16081 aaaaataagc caaataaatt aaaatgtgct ataataacaa tatagtagaa ctattttaag
    16141 gaggagtaaa tttctatgaa taaaaaactc acagattatg tgattgatct ggtggaaatt
    16201 ttaaataaac aacaaaagca ggttttctgg ggaatatttg atattttcag tatggtggtt
    16261 tccatcattg tatcttatat tttattttat gggctgatta atccagcacc tgttgactac
    16321 attatctata cgagtttggc cttcctgttc tatcaattga tggttgattt ttggggcttg
    16381 agcgcgagta ttagtcgtta cagcaagatt acggatttca tgaaaatctt ttttggtgtg
    16441 actgctagca gtgtcttgtc atatagtatc tgttatgcct tcttgccact cttctccatc
    16501 cgttttatca ttctctttat cttgttgagt gccttcttga ttttattgcc acggattact
    16561 tggcagttaa tctactccag acgcaaaaaa ggtagtggtg atggagaaca ccgtcggacc
    16621 ttcttgattg gtgccggtga tggtggggct ctctttatgg atagttacca acatccaacc
    16681 agtgaattag aactggtcgg tattttggat aaggattcta agaaaaaggg tcaaaaactt
    16741 ggtggtattc ctgttttggg ctcttatgac aatctgcctg aattagccaa acgccatcaa
    16801 atcgagcgtg tcatcgttgc gattccgtcg ctggatccgt cagaatatga gcgtatcttg
    16861 cagatgtgta ataagctggg tgtcaaatgt tacaagatgc ctaaggttga aactgttgtt
    16921 cagggccttc accaagcagg tactggcttc caaaaaattg atattacgga ccttttgggt
    16981 cgtcaggaaa tccgtcttga cgaatcgcgt ctgggtgcag aactgacagg taagaccatc
    17041 ttagtcacag gagctggagg ttcaatcggt tctgaaatct gtcgtcaagt tagtcgcttc
    17101 aatcctgaac gcattgtctt gctcggtcat ggggaaaact caatctacct tgtttatcat
    17161 gaattgattc gtaagttcca agggattgat tatgtacctg tgattgcgga cattcaagac
    17221 tatgatcgtt tgttgcaagt ctttgagcag tacaaacctg ctattgttta tcatgcggca
    17281 gcccacaagc atgttcctat gatggagcgc aatccaaaag aagccttcaa aaacaatatc
    17341 cgtggaactt acaatgttgc tagagccgtt gatgaagcca aggtgcctaa gatggttatg
    17401 atttcgacag ataaggcagt caatccacca aatgttatgg gagcaaccaa gcgcgtggcg
    17461 gagttgattg tcactggctt taaccaacgt agccaatcaa cctactgtgc agttcgtttt
    17521 gggaatgttc ttggtagccg tggtagtgtc attccagtct ttgaacgtca gattgctgaa
    17581 ggtgggcctg taacggtgac agacttccgc atgacccgtt actttatgac cattccagaa
    17641 gctagccgtc tggttatcca tgctggtgct tatgccaaag atggggaagt ctttatcctt
    17701 gatatgggca aaccagtcaa gatttatgac ttggccaaga agatggtgct tctaagtggc
    17761 cacactgaaa gtgaaattcc aatcgttgaa gttggaatcc gcccaggtga aaaactctac
    17821 gaagaactct tggtatcaac cgaactcgtt gataatcaag ttatggataa gattttcgtt
    17881 ggtaaggtta atgtcatgcc tttagaatcc atcaatcaaa agattggaga gttccgcact
    17941 ctcagtggag atgagttgaa gcaagctatt atcgcctttg ctaatcaaac aacccacatt
    18001 gaataaaaaa gaaaaacgca tattatcaag ttaaataacc ttggtaatat gcgttttatt
    18061 atgtagagac ttatactctt cgaaaatctc ttcaaatcac gtcaacgtcg ccttgccgta
    18121 tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt gagctgactt
    18181 cgtcagttcc atctacaacc ttaaaacagt gttttgagca gcccgcagct agtttcctag
    18241 tttgctcttt gattttcatt gagtattact tcattttctt ctgaaataga gttgtcgccc
    18301 agtctatgct attgaaaata cgccaaaact tctaagggtt tgtgagcgat ataatcaggt
    18361 tgatagttta gtagatctgc ttgctctcca aatccccaag tgacggccaa tttctgaata
    18421 cctgtttctc gagctcccag catatcaaac ttggtatctc cgatgatgat ggcttgttct
    18481 ggtgctagtt gatgtgtctg taaggcttgg tgaatgacat ctgccttatg gggtgcttca
    18541 gggctagaac cataaatacc atcaaagaaa tgatggattt ccaagttttt ggccatgtct
    18601 tgagcagtag atgtattctt tgtcgtggtg atgtagagtg gataactgct cgataactcc
    18661 tcaagcaagt ctataatctg aggaaagagt tgagcttcat agatgccttt tgccttatag
    18721 taagaacgat atatctgcat ggcttcagaa atttggtctt tggacaggca ggtcgcaaaa
    18781 ctactttcga gaggtggtcc cataaaacca cgaatagttt tggcatcagg gctaggcacc
    18841 cccagctctt taaaagtata ggtaaaggca ttgtgaatcc cgatagaact atcaacgagg
    18901 gttccatcca aatcgaaaaa aatcgctgtg atagaggtca tggtttctcc tatttgataa
    18961 gcttattctc cgaaaatctc tttttggagg cgacgaccag taggggtggt agcgagtcca
    19021 ccttcagctg tttcacgaaa ggcagttggc atgcttgctc ctacttggta catggcatcg
    19081 atcacttcat ccacagggat tttagattcg atacctgcca aggccatgtc tgctgcgatg
    19141 aaagcaaagc tagctcccat ggcattacgt ttgacacagg gaacttcgac caaacctgca
    19201 acagggtcac agatgaggcc tagcatattt ttaatgacaa aggcaatagc ttgactggcc
    19261 tgataaggtg ttccacctgc agccagagtc aaggcggcag cactcatagc agaggctgaa
    19321 ccaacttcag cttgacaccc accctcagca cctgagatgg aggcattgtt tgcgatgact
    19381 agtccaaagg caccagcagc aaagaggaaa tccaattgtt gctcgtggct gaggtctaat
    19441 ttttcaatag cagcagtgag aacggaaggg agacaaccgg cacttcctgc ggtaggagta
    19501 gcgcagacca agcccatttt agcattgtgt tcattgactg cgatagcatt tcgggcagca
    19561 gagagaatcg tgtaatctga taaagttttt tcgtttttga tgtagtgatc caatttggca
    19621 gcatctccac ctgtcaggcc actacgagat ttattttcat tgaggccaag ttggacagag
    19681 gctttcataa cttccagatt gcgttccatg agaaggaaga cttcttcacg ttcgcgaccg
    19741 gtcaattcaa actctgttgt aatcatgagt tctgcgacat ttccttgaaa gtccagatct
    19801 gcttgctcga ccaattcttt gatagaataa aacatgcttc ctcctattta aagaaattga
    19861 cattgtggag atgagggatt tttcgaattt cttcgatagc ctcatcacag ttgcgactgt
    19921 caacttcgat aatcataatg gctttttcac cagctttttc acgagtgaca ttcatctggg
    19981 cgatattgat accatagcgg gaaagcgcct ctgtaacaag ggcaatcata cctggaatat
    20041 cttgatgaac gatgatgata gtcggtgtat tcatattgag agagacggca aaaccattga
    20101 gttcggttac ctgaatattt cctccaccga tagaaatacc agtcacgctg atggtcttgt
    20161 gggcattttt aacagtaatt ttagtggtgt tagggtgagg ggcattgctg tctttctgaa
    20221 tggtccagac aatcttgata ccacgcttgt gggcaatttc cagactattt ggaatttcag
    20281 gatcatctgt atccattcct aaaatacctg caacaagggc taggtctgtt ccgtgaccac
    20341 gataggtctt ggcaaatgag ttaaaaagtt ggaattcaac ttctgtcgga gtatcatcaa
    20401 aaatggaaga gacaatcttc ccaatacgaa cagcaccagc ggtatggcta ctagatgggc
    20461 caatcataac tggtccgatg atatcaaaga cagattgaaa acgaagtgat ttcatcagtt
    20521 tccccttata aaaattctta tctctattat atcaaagaat gaggggcttg gctttaattg
    20581 tggatgaaaa cctttctaat acctcaaata gcataaaaat agtatctttt atgacaaaaa
    20641 acaccttatt tagggaaata aaaaataatt ttgtaatatt tctacataaa agtgtcaaga
    20701 aacggtaata tttaaagggt atgatagaac tatagaaaga aggagaattt tcgaatatga
    20761 aatcaataac taaaaagatt aaagcaactc ttgcaggagt agctgccttg tttgcagtat
    20821 tttctccatc atttgtatct gctcaagaat catcaactta cactgttaaa gaaggtgata
    20881 cactttcaga aatcgctgaa actcacaaca caacagttga aaaattggca gaaaacaacc
    20941 acattgataa cattcatttg atttatgttg atcaagagtt ggttatcgat ggccctgtag
    21001 cgcctgttgc aacaccagcg ccagctactt atgcggcacc agccgctcaa gatgaaactg
    21061 tttcagctcc agtagtaagt gaaacagttg tttcaactgt aagcggatct gaagcagaag
    21121 ccaaagaatg gatcgctcaa aaagaatcag gtggtagcta tacagctaca aatggacgtt
    21181 atatcggacg ttaccaatta acagattcat acctgaacgg tgactactca gctgaaaacc
    21241 aagaacgtgt agcagatgcc tacgttgcag gacgttacgg ttcatggact gctgctaaaa
    21301 acttctggct taacaatggc tggtattaag aactaacgaa caaataatat gtaaagagtc
    21361 gaggaaatcc ctcggctttt ttatctttcc ttcgcttggt aatagatctc tacttctttt
    21421 ttgagatgag acagcataga agtttcctcg gttagctcca gaagggagaa ccctttttgg
    21481 ataagtttag aatcgtctgt acaaatccca atacggacat agcagatagc cagcctatcg
    21541 tagcttttct tattcttggc gtcctctagt aaagtgtagc agatttgctt acacatgttt
    21601 ttatcttgat tgtatagata gagtgtggaa aggttgagca ggattgctat ttgcaagtca
    21661 tataaatgtt gatagttttt atagacttct aagcgttgca agattttctc ggattattga
    21721 caaataaacg gacattctga tagacgattg ccctagcggc ttagtgtaaa ctttacaaat
    21781 ttggcttgta atttttttat aaaattcact tcagttactt gacagttatt atattttcac
    21841 ttattatata gataaaagga tgagatggga gtttaaaaat ttgaaagcgc tatccatatt
    21901 gtttattgga ctgattcttg agtaatagtt agagtgtgct taatactact ctggttgttc
    21961 aaggacctga tacagaagcg caccattctc tcggttaaga gtaagttcgt tgttaaaaaa
    22021 tgaaatgaga tagaaggaag gtgagtccaa tggactacga tacttgttga taaattacta
    22081 tagctgtttt tacggaagag ctctcgataa taggagaaat aaatcatgag aaaattagtt
    22141 aaaattggtg ttgcatcttt aatggtatgt agtatacttg cttctacaag tgttttggca
    22201 gtatgggttg atggtggtca atggaactat ggagtaggat ggtcaggaaa ttttggttat
    22261 tctgattatt tacattctac tcgctctcat acagcaactg ttaaagatgg aaataaattc
    22321 tctaaggatc gtgcagaagc tgaggcatgg gctcgggctt caatcttcaa attcccacca
    22381 acgggaatgg aatatttcta tggattttaa ttaaaattct ccctcccctt ttggagaggg
    22441 agtttcttca cgggaggtat ctctatgaaa aaaatcagtc atctttgtat gttactcctg
    22501 cttctgtgta ccactttttt tgtttttaat gtaaactata cacgagaagt ggttcggatt
    22561 caagaaatgg gaaagactgt agattctttg gatttgtatt tgaaagatat taacgaacct
    22621 gcagcgtctg ttcttcgatt ttttgaggat gtatcaaagg agtataaagt ctccatcatc
    22681 aaaacagaca gtggtgatga ggtggtcaag tctggtgttt ttgataaaga taccttcccc
    22741 taccaagagt ttgggatttc ttctcttgat tttaccacag atggtgaagg agtctatagt
    22801 aataaagaaa tttccaataa acttggtacg attccgacct ttctaaaagc caaacctatt
    22861 cagcttatga cttttcaaac ctatatcaag gatacatctc gtagtttaaa tggtcgctat
    22921 acgataactt ctacacaaga gatggacaag gataggattg tacagaaatg gagcgatttt
    22981 ttcaagatag accaggctac cttgctagag ccgacctaca aaagtgcagt ggaagtcata
    23041 aatcgagatt tgcttttatc tgccattgtt tttgtcttgg ctattttgct tcttgtgtta
    23101 gtgacagtgt atcaaccgat gatggagatg aaaagagttg gggtacaaaa attacttggt
    23161 tttcaagata gggctgtttt agctgatgtt gtaaaaggca acctttacct cctcctaggt
    23221 ggggctcttg tgatcaatct aggcgtgttt ttcttgcttg attataagcc aaaagatttg
    23281 tttcctatgc tgtggttgtc tcattttttg ctgttgcagc tttatctctt tatcagttgg
    23341 ttgacttacc tcttaatcca aaaaatgaca atcagctctc tgctgaaagg tttttcatct
    23401 ttcaaatttg gtctactctt taattatttg atgaaaattg gaactaccat tttactgaca
    23461 gtcttgctag ttggggtagg aaaaagtttg gagcaagaaa acaaagagtt ggattaccag
    23521 aaacagtgga tcagccaagg aaattatctg accttagaaa ctttccaact caatgataac
    23581 ttgtggcaag agcagttggc aggctcaggg aaggcattgg attatttcta tcgattttat
    23641 caggatttgg tagaaaaaac gcaggcgggc tatgtgcaga gtagcagtct tcctgtaaaa
    23701 aattttgtcc aatcagaaca gattcagcaa tatcagttaa cagatacggt ggatgtttac
    23761 tatgccaatc gcaattttct aaagagcaag ggattcaagc taccagatac cggtattaaa
    23821 aaagttattt tgatgccagc aagtacgaaa ggtgaagaag ataaaaatca gctcttgggg
    23881 aagttaattg cctttcattc gatgaagtat gaagagcagc aaaaacgaac gatagaggag
    23941 atggatgtcg agattgccta ttatgaagga gattggtcat ttttcccata tagtgataag
    24001 cgaaaggaaa atctctccaa tccaattatt agcttggtca atgattctga tatgatgtgg
    24061 gatgagaaag cctccctgtc aacaactggc ttaaataatc cgattaaaat tgaaaatacg
    24121 gttcaacatc aaaaagagat tacagagtta gttgagaaat tgtcagatgg aaattattta
    24181 aaattttcat ctattcaagc cattcaacaa gagaaagtgg attcttatcg agatgctgtt
    24241 cggaatttta acctactctt tgctttgttt ggtctcctta gcatgatgat ttcctacttc
    24301 ttactagtaa taactttctt attgaagcgc agggatatca ttaccaagaa gtttatgggg
    24361 tggaaactgg tcgatcgcta ccgtcctctc ctcgttctgc tcttgctggg ctatagtttc
    24421 cctcttctag tcttgatttt ctttgcccat gcgttcttgc cacttctgct gtttgcaggc
    24481 tttacatgtt tggatatact atttgtgcta gtcttggctt ctaggatgga gaaaagaagt
    24541 ctagtagagt tattgaaagg gggcatctta tgattgagtt ggaaaatatt accaaaacca
    24601 ttgggggaaa agtgattttg gatcacttgt ctctcaggat tgatcagggg gatttggtag
    24661 ctattgttgg aaaaagtggt agtgggaagt cgaccttgtt aaatttatta ggtttgatag
    24721 atggtgatta tagtggacgg tatgagattt ttggtcagac aaatctagcg gtcaattctg
    24781 ctaagtcgca aacaataatc cgtgaacata tctcttatct gtttcaaaat tttgccctga
    24841 ttgatgatga aacggtcgag tacaatctca tgctggcgct gaaatatgtg aaattgtcta
    24901 agaaagacaa gctcaaaaag gtggaagaga ttttagagag agtaggtttg tcatctactt
    24961 tgcatcaaaa ggtttccgag ttgtctggtg gcgaacaaca acgaattgca gttgctagag
    25021 ccatcttaaa acccagccag ctgattttag ccgatgaacc aacaggttcg ctagatcctg
    25081 aaaatagaga tttggtcttg aagtttctct tagagatgaa tcgcgagggg aaaacagtca
    25141 ttattgtgac ccacgatgct tatgtagccc aacaatgtca tcggatcatt gaattgggcg
    25201 aggggaaatg agtttgttca gctctttttg actgactgaa tactcatgtt tttcagagag
    25261 gaatagcata aatacgccta gaaatgacat ttttatgtag tatttctagg tttttttgtt
    25321 tcaaattgaa aatttttcca atttaggctt gacaaaggat gaagataggt gtattattta
    25381 tacaaccaaa aagaataaac ataaaggaga ctttgttatg aataagatga agaaggtgtt
    25441 gatgacgatg tttggtttag tgatgctccc cctactattt gcttgtagca acaatcaatc
    25501 ggctggaatt gaagccatca agtccaaagg aaaattggtt gtagccctca atccagattt
    25561 tgctccattt gaataccaaa aagtggttga tgggaaaaat cagattgtgg gttcagatat
    25621 cgaattagcc aaggctatcg caacagaact aggtgtcgaa ttggaactat ctcccatgag
    25681 ttttgataat gtactggcta gtgttcaatc aggaaaagcc gaccttgcca tatcaggtgt
    25741 ttctaagaca gatgaacgga gcaaggtgtt tgacttttcc attccctact atactgcaaa
    25801 aaataaactc attgtcaaaa aatctgactt gactacttat cagtctgtaa acgacttggc
    25861 gcagaaaaag gttggagcgc agaaaggttc gattcaagag acgatggcga aagatttgct
    25921 acaaaattct tccctcgtat ctctgcctaa aaatgggaat ttaatcacag atttaaaatc
    25981 aggacaagtg gatgccgtta tctttgaaga acctgtttcc aagggatttg tggaaaataa
    26041 tcctgattta gcaatcgcag acctcaattt tgaaaaagag caagatgatt cctacgcggt
    26101 agccatgaaa aaagatagca aggaattgaa agaggcagtc gataaaacca ttcaaaagtt
    26161 gaaggagtct ggggaattag acaaactcat tgaggatgcc tttaaagcat ccattgaaaa
    26221 atagaaagaa ggaaaagaac atgagtaaag aaaaagtaat tttggcctat tctggcggtt
    26281 tggacacatc agttgctatt acctggttaa agaaagacta tgatgttgtt tcagtttgta
    26341 tggatgtggg tgaagggaaa gacttagact tcatccatga taaggctctc aaggttgggg
    26401 cagtcgaatc ttatgtcatt gatgtcaagg acgaatttgc tacagattat gtgctagtgg
    26461 ctcttcagtc acatgcctat tatgaacaaa agtacccctt ggtatctgcc ttgagccgcc
    26521 ctcttatttc taaaaaatta gttgaaatag cgcatcagac aggagcgact acaattgctc
    26581 atggctgtac cggtaagggg aatgaccaag tcgaatacca gattgcagtc gctaagaaag
    26641 cgaatgaagc taaaaagtga tggagtgatg ggttcagaat aagaggttgg tcgattggta
    26701 gtctctttct tgtcgttgaa aaagtgagat atattgactt ttgaaaaaaa tgtcataatt
    26761 gagttgggat aaacgtaaaa gtcatacttt ctcgttaaat cgttcggcga ttcatggtga
    26821 catggacaca tagtagtaaa cacactatgt ggcttggcag agctaaaaac ttctggctta
    26881 acaatggctg gtattaagaa ctaacgaaca aataatatgt aaagagtcga ggaaatccct
    26941 cgactttttt tataatttct ttggttgata atgggtctct acttcttttt tgagatgaga
    27001 cagcatagaa gtttcctcgg tcagctctag gagtgagaac cctttttgga taagtttaga
    27061 atcgtctgta caaatcccaa tacggacata gcagatagcc agcctatcgt agcttttctt
    27121 attcttggcg tcctctagta aagtgtagca gatttgctta cacatgtttt tatcttgatt
    27181 gtatagatag agtgtggaaa ggttgagcag gattgctatt cgcaagtcat ataaatgttg
    27241 atagttttta tagacttcta agcgttgcaa gattttctcg gattattgac aaataaacgg
    27301 acattctgat agacgattgc cctagcggct tagtgtaaac tttacaaatt tggcttgtaa
    27361 tttttttata aaattcactt cagatacttg acagttatta tattttcgct tatgcttatt
    27421 atatagataa aaggacggga taggagttta aaaatttgaa agcgctatcc ataataataa
    27481 cgcataattt tctccttttc gtgaaaaaag ttaacgtaat tttaaaatga gcttaataag
    27541 aggtactatg taggtagaaa ataaagatag gagaaaaagt atgaataaaa aaatattttg
    27601 tattctggta tgtattatat cattgattag tctagctata atctttccat ggggctggtc
    27661 gatataatgt aagggagctt gagttgttag tggaggataa aatgttaaga gtaatagtag
    27721 ttattcaatc tttagtaata atactgcttg ctgttgcttt attattatct cggaaaaact
    27781 ttgattcgtt aaatgttgtt cttataatga tgatcgtatc acaattgttg ttattagtat
    27841 atttgataaa atcagggaat cagtgattag ctgttatttg aattaagtaa actgttaagc
    27901 ttcaagcagt aactggtttt aaatatttaa aataagataa aggaaggaag tctaatttag
    27961 gtaactaaac aaagcctgcg atcacttgtt aggaaactat cctaaccatg cttaataaaa
    28021 aaggagaaaa taaatggaac tcgtattacc aaataattat gttgctcttg agcaagaaga
    28081 gatgatgtat cttgatgggg gtggtgttgg tcgtaactgg tggaatagta gaggtagttt
    28141 tgcaacagtt ttggatgtag gtttggccat ctatagtggt ggtgcaacaa tttattctgc
    28201 ttatgcgata aaaaaagcta tctcagctaa tagaggggct attacgagaa cattacgtag
    28261 tttaataatt aaacatgtag gtagtgcagc tggccattta gtcaatactg cactaaacgt
    28321 tgcactaact gttactggat tttcactagg tggagcaatc gcatatgggg ctgattgggc
    28381 tgacggtagc ttagatggtt atatttttgc ttaaaatgaa acattttttt gcaggaattg
    28441 gtgaaattca ttttttgtta tttttattat atctaagcat gtctgctagt ccaattattg
    28501 gactagtgat tggatatact aaaataaatc taataaattc tattattata gctcttggta
    28561 tgatattggc attaattttg gtattatcaa gagtgtatag aaaatatttt tatagagacg
    28621 atgatgacta aagtttttat caataatttg ggctccttgt caactgtagt gggttgaaga
    28681 aaagctaacg tctggggaag gggttaaagc tttgctttat caaatattga cttacagagt
    28741 tgctctattg tattgatgta ttcttagtaa ataatatggt gttttgaatg aaagatgatc
    28801 agaaatattt attagcggga ctttattcgc ttctagttgc aatattttat tttccattga
    28861 ttgagtccaa ggggattttt gtaagtatat tgatggcggt tttactttta tatttaatat
    28921 acttcattgg aacagtcatt catattgtga taattaagtt tataagaaaa aaatctttta
    28981 agtatttggt tctatatcca tttacttatg atgggagctg gagatttcaa cctataaact
    29041 tactctactt tccagaaatg gtgagagatg tcattccgat taatttagtt caagaatatt
    29101 gccaaggaca accttacggg ctgttaaaaa agatgctgaa aagaattcga ttgtcacgag
    29161 agatagcttt actcctggct accattatcg tctatttttt tacgcataga attctacctc
    29221 tttcagtatt tacgttcatg ttttcttaca tattgatatt tgcacaatct tatttgggtg
    29281 gtaatactgc ttggattgga aatagaagat taataataga tgatgaattt gaaaaaatct
    29341 tgctttcaaa aagttatata aaagaaatat catctgcacg atactcggaa tacttgacat
    29401 gtgaatacaa aaaccttaca ccaatcatat tgttagctat ttttgaaaat ttacttgact
    29461 cctacttgct tcagaatcag agtgaggttg acttagatat tttttataaa gttttacctt
    29521 tgctttataa agaaaaatat actatgggat tcaattactt tgtaagttta aattatttac
    29581 tatataaggt tggatttttg ggaatcattt acgataatga agcattagga gatttgtcaa
    29641 aacaatattt aaacagaaat atttcggaat tacaagatgg ttctttcgag ggcggtatac
    29701 aagatgctgt tgcctctaaa caaatagtag ttataaatga atttatagct tgtttaaatt
    29761 ccagatgcat gccatcccaa tatgatagat ttttttataa agatagacct tatatttttt
    29821 ccagaaagag tcctattaag aggtgaaaat ttgttacatt tggattaaca agtgtcctag
    29881 ggattagaaa taactctagt atagctagat atttttgagt aactagaaat atcattaggc
    29941 tacccatatg attgccagaa aagatggctg atgaatctta tttatactgt tgcagtaggc
    30001 gttgtctagg ataaataagc tatcttgatg ggggagattg gaataatttt agtagaaaca
    30061 ttaaaggatt atgggcaagt agcacaggat taggtgatgc aatgtgctaa gttggcttgg
    30121 tgttagcagt agtattattt aacaatggaa agtagactaa atgaaaaata aacgttattt
    30181 ttttgacaca attttaatga ttttactact tataagcacg atattttgtg tcagcccagt
    30241 atttataaaa ttggacatct taggaactcc ctctcatgcc atcttaacct ttgtattggc
    30301 gataccgtta ttctatattt tgtctcaatg cttacatact ttgctattac tagtttcctc
    30361 aatcttttgt aaattaagac caatttattt ttattttata tttgtgatca ttataggagc
    30421 taggaaatac tatcgaattc tctttcacca actaatggga tttagtccag gaatagcagt
    30481 gttttataag gagagtcaaa caactaagaa tctgtttaaa ttttactact tcttgtactt
    30541 tacaacacta atttcatact attttttctt tacttttgtg tatgacaaac cgttgctttt
    30601 gcctcttatt ccattttcta ttatcatagc attagtacaa aaactttata gaattgagaa
    30661 tcagcaatta tttctgttaa aatcaaaggt actaacaata ctggaatcta agaagaattg
    30721 tgagtttaat cttcaggatt atcatgaaat ttggaaattg caatcaaaat ctgagttgcc
    30781 atgcgtggct ttatcttata tcagtttgat caagccatat ctttcagaga gcgtgcgtga
    30841 acaaattgat ttattagaag ttaagcgatt taaaaaaata aatcatccaa tatcacttta
    30901 tggtatgttg gatgttataa aattaaatct atatttacgg cattataatg aaaaaataaa
    30961 tatgaatcaa tgttaaagaa aattttagag gtaagaccag actttgtttt aatcgagcag
    31021 aatattgatg atagtttaaa tagctcgcaa ccattatctt tatctttagc tatttcagaa
    31081 atccaacttt tgcttgaagt gtatataggg atcaaacatg tttcaattag gagataaaac
    31141 tagaataaca tttgctatta taggggcaag ttgcatatta gtcagtatgt atcttatacc
    31201 tctcattaac acggataata aattttggga aatactttta tttataatag gtgtattgct
    31261 aattggaatt gcgttactaa gtcaaaaaaa ataaattttg aaatagtatt agtgagttcg
    31321 caatcattta ttgctagtgg tttagaactg ttaagtttca agcaataatt ggttttaaac
    31381 cttaggtaac ctataaaaac aaataaggta gagaaaggat atcttattta ggtaactaag
    31441 tactataaac acagtcgaca atcacttgtt aggaaaccat cctaactatg cttaataaaa
    31501 aaggagaaaa taaatggaac tcgtattacc aaataattat gttgctcttg agcaagaaga
    31561 gatgatgtat tttgatgggg gattttctat tccgagatgg cctgttgcaa cagccattaa
    31621 tatagctttt aatgatgtct taggtggagg agcaatcagt ctagttagaa attatattcg
    31681 taattatggt ttgcggcgag ttacaagcgc aattgctgga gcagctgcaa gatatgttgg
    31741 ggtacgagtt gcaaatagag tggcaggatt tgcactgtct gctattaatg gatttgcagc
    31801 ttggatgtca attggcaatg ctattacaac aatctgggcc aataatgatg taaataggag
    31861 agacccaaat ttaaacgcct tgtggtaact agatatgggt attaaaatgg aaaaaatttt
    31921 tgttattatt ttttttgtat gtctatttat atcatccata acttttttag cctatgattt
    31981 tgttagcgaa gaaataaaaa agttgattat ttggatgaat gtcgtttttt tgattttaat
    32041 catagcaatg ataatttatc caaaattaag aaaatgataa ggacactgta aaattatgat
    32101 acgtaaacta atcatttttt tattaatgct ccctcttttt gtcttgtggc tagagttgca
    32161 tgtcctagtg aataacttac tattgaatct agaatctccc cttgattttg tgattagtat
    32221 gagtcttgct ttctgtagtt tgattttatc aaaaatagtt ttagacatac tatacgcatt
    32281 gaaagatttg tacaagaaag aagctcttat tacgattttt ccttttattt ttataggcag
    32341 gaagaaagta aatgtgaggt tctcgcccta tttttcattc catcgtaaaa gtttgtcgcc
    32401 tgatgattta agatctagga ttatatggag ttttattctt gaaattgcta ttatcctagt
    32461 atttatttta aaaattcctt ttgcaatcat catgcttact acaatatttt tctggactat
    32521 aatggatatc aatcatctcg tttttaataa gacggaattt ctttttaatc aaaacaaatg
    32581 gcaaaaagaa gattcgtttg aaagtgattt gacgaaaacg ttaaaggata agatacaaaa
    32641 atcagagcta agttattctg acttaatgtc tcttcagctg tatgatgcga tgaaccaatc
    32701 caccttttta acggatagtg aactttttga ggatattttg aaaaaaatcg aagattctca
    32761 taacaccctt ctgtgtacag gtcttgtcga gttactgctg tatgaaattt ctattagtaa
    32821 caataacaac tggcaagaaa aggttgataa aattagaata cagctcatca gaatcaatca
    32881 attagatttt ttctattata caagttggtt aaggcaaaat tttgatttct gtatgaatag
    32941 agagtatcat aaaatgaaat ctcggaaatt attactgagt aataaaaaga tagtttaagt
    33001 tcgtcctatt tgtaaaacaa atgaaacaat ttcaactaag gaggagaaaa caaatggaac
    33061 ttgtattacc aaataattat gttgtgattg atgaagaaga aatgatgtat cttgatgggg
    33121 aagcttattt aagcaagcgt gcttgtcaag gaatttgcgc agctttagct atgagttcag
    33181 gaacttttat agcattagct ggagctgcag ttttaaccaa aaaactaata aactatatta
    33241 aggttggagg tcttggaggc tggcttattg gtgcagcagc aggtgtattg gctacagcag
    33301 cagggaaaat agcttactat attggatatg gtgttcttaa tagaggttgt gatattaacg
    33361 ggaaccctta tccttgggat ggattcatat ctgcgacagt aaaatgagta atgtagataa
    33421 gattcgaaaa atacacatta tcgtatgttg gatgtatata tttttatcat tcagggcgat
    33481 tataaatgac acggagtatt ttttgcttat ttttttagct tttatctact caatagtatc
    33541 actacctcta tattctgtga aaaataaaat agtatctatc tgtctagcca taaattcgat
    33601 tctgttaatg agtttcccca ttttaatcaa taagtttttc ccagaaagtt ttttgactta
    33661 taccgtatta ataagtgttt ttattacaga gttgataatt tttcatttaa ttgggaaaga
    33721 ttttgatatt aaattgacta acgaatataa gaaaattagt cagtttagaa gcaaggtgtc
    33781 tcaatctcct tggataaaat atttagagat ttctagtttt atattaacta tatttccatc
    33841 tattctttat ggtacagttg ataatcatgt actgactctt atctttttga taaaaatttg
    33901 tgcagatacc acgataaaat ttttattcat cagattattt gacacaagta ctttaatgaa
    33961 gaggagaata ttttttcttt tcgcattgga tgttatagct tacttatttt taggatatct
    34021 tttagtgatt caaaaagcag gctatttgtt ttcggtttta cttctttttt ctaatttttc
    34081 agttccattt atcaaagaaa aggaattcga attatttaaa aatagcaagt aatagaaaca
    34141 taggttaaat cttagaacgg cttaaaatca gatatgataa agggaaatag tcttatctag
    34201 gtaactaagt gctacaaaca caatcgagga tcacttgtta ggattacatt ttaatcatgc
    34261 ttaataagaa tggagaattc ctatggggat tgtattactc tgaagtttcg aataccttag
    34321 ttctcgtgat tttgagctat tctaggttta gaatccttca gaatgtaaaa ttttaagcag
    34381 tcaaagactt agaatagccc gaaaacattt attttatagc aattctaggc ttagaattgc
    34441 tcatatatat gtatttgagc tgctcgatag ttaggatagc tctattctga gaaatctgag
    34501 ctatcaatgc ttcagaatag tattcgccaa tggtttttat tgaagaggtg attgttttat
    34561 gatagtctaa aataaaactg atttaataga gtaaatggag aatcgttaca tgaaacattt
    34621 ttttgcagga attggtgaga taaaacttgt tggctactta ttgtatatat gtgtaggact
    34681 agctcctctt tttcatatat atgtcatagg ttcggaactg agttttgtga aaatagtgtt
    34741 atctattttg ggagttatat ttgtaagtat gttaactatt gctcgaattt atcggacttt
    34801 tctataaaga atagtttgga cttgaactgt atctaaaaac agaggttggt cgattatcag
    34861 cctctttctt gtcgttgaaa agagtgagat atattgactt ttgaaaaaag atgtcataat
    34921 tgagttggga taaatctaaa aataatatag tagattgaat ctggaatagt ccgttatgac
    34981 tgttaaaata tttctagaaa ttaatttgac tttcctaatc gatttgttca tatcttgttt
    35041 caatctacta tactttctcg ttaaaccgtt cggcaattca tggtgacatg gacacatagt
    35101 agtaagcaca ctatgtggct tggcagatct aaaaactgtt cccttgcgat aagcctaata
    35161 agcacaacat agggagttag agaagccgac tctaatcaac cactttgggc agtagtgaga
    35221 actgccccgt gctttttatt ttgagaaaat atggagtttg tcgttgaaat tacttgattg
    35281 tattttggat tatcaagaaa gattcaatgg aaaaacatgt caagtatcaa cgaattataa
    35341 gtatttagag actttcaaag tgaatttttg cttgactgat ttacatcatt tatttgactt
    35401 acacaaaatc acacgagatt atgctagtca aacaaaacct gctattcaag ctggtgtttt
    35461 tattttagaa gattttagaa atatcctatg tacaatgatg taatcgaaag gatatcttta
    35521 tgtgagttta tcggcgatat cttctatatc taagctagca agttgttgca tcgtagctaa
    35581 ggatttatct aaaaatacta tgaaattgga cgtcatattt tttgaggata aaaataaaag
    35641 atccgcagtt ttaggtttac gaagagacaa aagcggagta tttaaaccag ttactctaca
    35701 ttttacaagc gctaagaaat atgctaaagt tcgtaaaaca gatgtgaaag aaatgaaatg
    35761 gctataaaga ttgtccgcag gcttaagctt gcgttttttg ttgtttaacg aaattaaaaa
    35821 acaagctctc tcatcggaaa tgtttttata ggaatgaagg aagatgatgc tatgtttaaa
    35881 aagagaatcg aaaagggcaa aagtagtgtc tttatctttt tggagtagaa gcttatgata
    35941 tagaaatttg taataaaaat gtaatataaa acatttgaca aatatttacg gggggagtat
    36001 acttaatata agtatagtct aaaaatgact atcagaaaag aggtaaattt agatgaataa
    36061 gaaaaaaatg attttaacaa gtctagccag cgtcgctatc ttaggggctg gttttgttgc
    36121 gtctcagcct actgttgtaa gagcagaaga agcccccgta gctagtcagt ctaaagctga
    36181 aaaagactat gatgcagcga agagagacgc tgagaatgcg aaaaaagctt tagaagaagc
    36241 aaaacgtgcg cagaaaaaat atgaggatga tcagaagaaa actgaggaga aagcgaaaaa
    36301 agagaaagaa gcttctaaag aggaacaagc tgcaaatctg aaatatcaac aagagttggt
    36361 taaatatgct agtgaaaaag attcagtaaa aaaagctaaa attctgaaag aagtggagga
    36421 agctgagaaa gagcataaga aaaaacgagc agaatttgag aaagttagat cagaggtaat
    36481 tcctagcgcg gaagagttaa aaaagactag acaaaaagca gaagaggcta aagcaaaaga
    36541 agcagaactt attaaaaaag tagaagaagc tgagaaaaaa gttactgaag ccaaacaaaa
    36601 attggatgct gaacgtgcta aagaagttgc tcttcaagcc aaaatcgctg agttggaaaa
    36661 tgaagtttat agactagaaa cagaactcaa agggattgat gaatctgact cagaagatta
    36721 tgttaaagaa ggtctccgtg ctcctcttca atctgaattg gatgccaaac gaactaaact
    36781 atcaacactt gaagagttga gtgataagat tgatgagtta gacgctgaaa ttgcaaaact
    36841 tgaaaaaaat gtagaatatt tcaaaaaaac cgatgctgag caaactgaac aataccttgc
    36901 tgcagctgaa aaagacttag ctgataaaaa agctgaattg gagaaaactg aagctgacct
    36961 taagaaagca gttaatgagc cagaaaaacc agctgaagaa actccagctc cagcaccaaa
    37021 accagagcaa ccagctgaac aaccaaaacc agcgccggct cctcaaccag ctccagcacc
    37081 aaaaccagaa aaaacagatg atcaacaagc tgaagaagac tatgctcgta gatcagaaga
    37141 agaatataac cgcttgcccc aacagcaacc gccaaaagca gaaaaaccag ctccagcacc
    37201 aaaaccagag caaccagttc ctgcaccaaa aacaggctgg aaacaagaaa acggtatgtg
    37261 gtacttctac aatactgatg gttcaatggc gacagga
//
LOCUS       DAVBOM010000018        35462 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBOM010000018 DAVBOM010000000
VERSION     DAVBOM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.018"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(1..139)
                     /locus_tag="VQ878_000939"
                     /pseudo
     CDS             complement(1..139)
                     /locus_tag="VQ878_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            125..610
                     /locus_tag="VQ878_000940"
     CDS             125..610
                     /locus_tag="VQ878_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET3095290.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            694..1401
                     /locus_tag="VQ878_000941"
     CDS             694..1401
                     /locus_tag="VQ878_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3095291.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1402..2733
                     /locus_tag="VQ878_000942"
     CDS             1402..2733
                     /locus_tag="VQ878_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET3095292.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2900..3775
                     /locus_tag="VQ878_000943"
     CDS             2900..3775
                     /locus_tag="VQ878_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET3095293.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3893..4756
                     /gene="pstC"
                     /locus_tag="VQ878_000944"
     CDS             3893..4756
                     /gene="pstC"
                     /locus_tag="VQ878_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3095294.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4749..5564
                     /gene="pstA"
                     /locus_tag="VQ878_000945"
     CDS             4749..5564
                     /gene="pstA"
                     /locus_tag="VQ878_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3095295.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5566..6318
                     /gene="pstB"
                     /locus_tag="VQ878_000946"
     CDS             5566..6318
                     /gene="pstB"
                     /locus_tag="VQ878_000946"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3095296.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6333..6983
                     /gene="phoU"
                     /locus_tag="VQ878_000947"
     CDS             6333..6983
                     /gene="phoU"
                     /locus_tag="VQ878_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3095297.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7051..7476
                     /locus_tag="VQ878_000948"
     CDS             7051..7476
                     /locus_tag="VQ878_000948"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3095298.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7650..8030)
                     /locus_tag="VQ878_000949"
     CDS             complement(7650..8030)
                     /locus_tag="VQ878_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3095299.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8242..9258
                     /locus_tag="VQ878_000950"
     CDS             8242..9258
                     /locus_tag="VQ878_000950"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3095300.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9280..10179
                     /gene="galU"
                     /locus_tag="VQ878_000951"
     CDS             9280..10179
                     /gene="galU"
                     /locus_tag="VQ878_000951"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET3095301.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            10597..11529
                     /locus_tag="VQ878_000952"
     CDS             10597..11529
                     /locus_tag="VQ878_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095302.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDDKFKDKATLENNVKEINKQIDFIKKVDETFKQKKLDE
                     TVKSLTDIADKFQKQIDVLKKEEEQKASDKAKEDKKKEESTSSQSSNSSSQASSSSFS
                     SYSGNSDYAPEQTYTADNSQSYSGSTGGDNSNYKAPAATDNGGNDGYILGHVTGADGS
                     QRDFYFNRSNGDVRDTSGNHVGNFGGGITDFRQR"
     gene            complement(11632..12309)
                     /locus_tag="VQ878_000953"
     CDS             complement(11632..12309)
                     /locus_tag="VQ878_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET3095303.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
     gene            complement(12293..12832)
                     /locus_tag="VQ878_000954"
     CDS             complement(12293..12832)
                     /locus_tag="VQ878_000954"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET3095304.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTAFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(12844..13974)
                     /locus_tag="VQ878_000955"
     CDS             complement(12844..13974)
                     /locus_tag="VQ878_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET3095305.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFVGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITETAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(14042..14740)
                     /gene="dapD"
                     /locus_tag="VQ878_000956"
     CDS             complement(14042..14740)
                     /gene="dapD"
                     /locus_tag="VQ878_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET3095306.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(14970..15881)
                     /locus_tag="VQ878_000957"
     CDS             complement(14970..15881)
                     /locus_tag="VQ878_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3095307.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSIVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(15946..18411)
                     /locus_tag="VQ878_000958"
     CDS             complement(15946..18411)
                     /locus_tag="VQ878_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3095308.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYSLLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            18553..19809
                     /locus_tag="VQ878_000959"
     CDS             18553..19809
                     /locus_tag="VQ878_000959"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET3095309.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(19887..21950)
                     /locus_tag="VQ878_000960"
     CDS             complement(19887..21950)
                     /locus_tag="VQ878_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3095310.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGSGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(21952..22230)
                     /locus_tag="VQ878_000961"
     CDS             complement(21952..22230)
                     /locus_tag="VQ878_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095311.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22382..23230
                     /locus_tag="VQ878_000962"
     CDS             22382..23230
                     /locus_tag="VQ878_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3095312.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            23852..24424
                     /locus_tag="VQ878_000963"
     CDS             23852..24424
                     /locus_tag="VQ878_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095313.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(25468..27726)
                     /gene="glgP"
                     /locus_tag="VQ878_000964"
     CDS             complement(25468..27726)
                     /gene="glgP"
                     /locus_tag="VQ878_000964"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET3095314.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVCSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(27752..29269)
                     /gene="malQ"
                     /locus_tag="VQ878_000965"
     CDS             complement(27752..29269)
                     /gene="malQ"
                     /locus_tag="VQ878_000965"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET3095315.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGYVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            29819..31090
                     /locus_tag="VQ878_000966"
     CDS             29819..31090
                     /locus_tag="VQ878_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3095316.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            31201..32493
                     /locus_tag="VQ878_000967"
     CDS             31201..32493
                     /locus_tag="VQ878_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3095317.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            32495..33337
                     /locus_tag="VQ878_000968"
     CDS             32495..33337
                     /locus_tag="VQ878_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3095318.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            33590..34390
                     /locus_tag="VQ878_000969"
     CDS             33590..34390
                     /locus_tag="VQ878_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET3095319.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            34400..35386
                     /locus_tag="VQ878_000970"
     CDS             34400..35386
                     /locus_tag="VQ878_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3095320.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
BASE COUNT        10850 a         7484 c         6670 g        10458 t
ORIGIN      
        1 cgctaattct tcttttaggg cgattgattt gtacttccgt cgcatcaatc attaccgtgt
       61 cctcagaact gagaggagtt cttgaaatcg taaaaccact ttgaacaaga gttacttcaa
      121 cccattggct ccgacggata aagaagactt gataagaact ctagagttag ctccccatgt
      181 tgaaggtggc tattttagac aaacaaaaaa agcttcagac actataaacc ttgctggtaa
      241 gggaagggcg ctttatacca gtatttattt cttattagaa gaaacgaatc cttcacattt
      301 tcaccgattg acagcagatg aaatctggta ttttcatgca gaatccccac ttactgttca
      361 catgattaca gcagatggtc actacgaagc agtcacttta ggcctggaca tatccaaagg
      421 gcaacaactt cactactgtg ttcctaaggg cactatttgg ggatcaacag ttgataagga
      481 tgatgctctg gtttcttgtc ttgttgctcc tggttttgaa tttgaggatt ttgaattatt
      541 tgaaagggta gatctactgg cgacctatcc agagcacaag gagatgattg agcgtttgac
      601 cagatactag tctttataag caaatttaat ctgatttagc aatgttagga tttctgataa
      661 ttgtgttata atgttaccaa taggagataa tagatgacaa aacaagtctt attagtggat
      721 gatgaagaac acattctgaa attgcttgac taccatttaa gtaaggaagg cttttctact
      781 caattggtaa caaatggacg gaaggcctta gctttggcag aaacagaacc ctttgatttt
      841 atcttgcttg atatcatgtt accacaatta gatggcatag aagtttgtaa gcggctgaga
      901 gccaaaggcg tcaaaactcc aattatgatg gtttctgcga aaagtgatga atttgataag
      961 gttttggcct tggaattagg ggctgatgac tacctgacca agccttttag ccctagagaa
     1021 ttactggcgc gtgtcaaggc tgtcctcagg cgaactaaag gaaaacaaga aggagatgat
     1081 tcagataata tcgctgacaa ttcttggcta tttgggacct tgaaagtata ccctgagcgt
     1141 catgaagtct acaaggcgaa taagttactg agtttgaccc caaaagaatt tgaactcttg
     1201 ctctatctta tgaaacatcc caacatgaca ctgactagag agcgtctttt ggaacgtatc
     1261 tgggggtatg actttgggca ggaaacacgt ttggtggacg ttcatattgg taagttgagg
     1321 gaaaaaattg aagacaatcc taaagcccct caatttattc gaaccattcg gggttatggt
     1381 tataagttca aggagttata gatgaaacgc taccttcaat tttggctagt caatctaagt
     1441 gttagcctca ttctgattgc agggatggca ttaacttgga tcagtaaagg catcggtctc
     1501 tttcttctag ccctttcttt gggactaggt ggctactggc tcttttgcct ttggaaatgg
     1561 gaagttgctt ttgagacctt gcaccaacct ctcttgacca gtagtgaata ctttttagaa
     1621 aaagggcaag aagacttaaa gtctttggct cagtatgtgt ctggcctaaa aaccaaagtc
     1681 tcccaacagg atcagcaata caaggaccta gccgaaacaa tggaggttct tctgtcgcac
     1741 ctaaccatgg ggacgttttt agtttccgct caaggtcaga tgttattatc cagtcgctct
     1801 ctgcctcatt attttcccga tgtggacggc gacataagtt cacttgatga cctcaaacgg
     1861 atggatattc ggaatttagt tcaccaagcc tttgatcaaa aaacaaggtt aaaacaagaa
     1921 gtaagtgggt ttcatgaggg tgacttgatt ttagaagtga cagcagttcc cgtttttagc
     1981 cccacccaat ctgtggaagc tgtgctcgtc ttgctatatg atttaacaac gattagaact
     2041 tatgaaaagt taaatttagc ctttgtctca aatgcctccc atgaattgag gacaccagtt
     2101 acttcgatta agggctttgc tgaaaccatt aaggggatgt cagctgaaga agaagcgctc
     2161 aaggatgact ttctagacat tatttacaaa gaaagcttgc gtcttgagca tattgttgag
     2221 catcttctta ccttatctaa ggctcaacaa atgcctatac aatggacgac cctttctttg
     2281 gcagaatttg tacaggattt gactcaaagc ttgcaacctc agctcaagaa gaaggattta
     2341 cagctaaagg tgcaggtgcc agatgatgtc accctcgtat cagatagtca attactttcc
     2401 caaatcttac tcaatctttt atccaatgcc atccgttaca ctgaacaagg gggaaaaatt
     2461 gaggtcaaga cccaaaaggt gaacgaaggc attaagattt ctgtatcaga tacagggatt
     2521 ggtattagtc aattagagca ggatcgtatt tttgaacgtt tttaccgagt taataaaggt
     2581 cgaagcagac aaactggtgg cactggtctt ggccttgcca ttgtcaaaga actcagtcaa
     2641 ttattaggtg gccaagtcac ggtgacgagt cagcttggca gaggcagttg cttcacgatt
     2701 tttcttccta accaatcttt cgcacaggac taataatttt taaagctatt tttaggagca
     2761 gccatttttc aaaagtggct ttttttgatt ctttacacaa tctttacatg aatcagggat
     2821 aaacctttac aaagacttgt tagactataa atgtagtaag cctacacaag aaaaatacat
     2881 agagataaag gtgattatta tgaaattcaa aaaaatactt actcttgcag ccattggctt
     2941 atcaggattt gggcttgttg cctgtggcaa tcagtcatct acttccaaac agtcagcttc
     3001 aggaacgatt gaggtgattt cacgagaaaa tggctctggg acacggggtg ccttcacaga
     3061 aatcacaggg attctcaaaa aagacggtga taaaaaaatt gacaacactg ccaaaacagc
     3121 tgtgattcaa aatagtacag aaggtgttct ctcagcagtt caagggaatg ctaatgctat
     3181 cggctacatc tccttgggat ctttaacgaa atctgtcaag gctttagaga ttgatggtgt
     3241 caaggctagt cgagacacag ttttagatgg tgaataccct cttcaacgtc ccttcaacat
     3301 tgtttggtct tctaatcttt ccaagctagg tcaagatttt atcagcttta tccactccaa
     3361 acaaggtcaa caagtggtca cagataataa atttattgaa gctaaaactg aaaccacaga
     3421 atatacaagc caacacttat caggcaagtt gtctgttgta ggttccactt cagtatcttc
     3481 tttaatggaa aaattagcag aagcttataa aaaagaaaat ccagaagtta cgattgatat
     3541 tacctctaat gggtcttcag caggtattac cgctgttaag gagaaaaccg ctgatattgg
     3601 tatggtttct agggaattaa ctcctgaaga aggtaagagt ctcacccatg atgctattgc
     3661 tttagacggt attgctgttg tggtcaataa tgacaataag gcaagccaag tcagtatggc
     3721 tgaacttgca gacgttttta gtggcaaatt aaccacctgg gacaagatta aataaaatgt
     3781 ttgctccata aatctctaaa gagatgcaga cgtttcatcg tacaataaga taaagaaggc
     3841 aagtagggag gtgtcgtatc tcccttactt tcttcactag aaaggacaag atgtgacaaa
     3901 acaagccttc aaagaagcag tttttagggc aatttttttc atgagtgcaa cagtagctgt
     3961 tgtagctatt ttgctaatct gtttctttat ttttagtaat ggcttacctt tcatggctaa
     4021 ctacggcttt gcccgttttt tattaggcag tgattggtcg ccaacgaaca ttccggcaag
     4081 ctatggtatt ttaccaatga tcgttggttc cttattaatt accttaggag cgattgtgat
     4141 tggggtgcca acaggcatct tgacatcggt gtttatggtt tattattgtc caaagcccgt
     4201 ctatggcttc ttaaaatcag ctatcaactt gatggcagcc attccatcta ttgtttatgg
     4261 ttttttcggc ctacaattat tggtgccttg gattagaacc tttttaggaa atggcatgag
     4321 tgtcctaacc gcttcgttac tattaggaat aatgattttg ccaaccatta tcagtttgtc
     4381 agaatctgct atccgaacag ttcccaaaac gtattattct ggtagcttgg ctctaggagc
     4441 tagtcatgaa cggagtattt ttagtgtcat cttgccagct gcgagatctg gtattttatc
     4501 agcagttatt ttaggaatcg gtcgcgcagt aggtgaaacc atggcagtta ttttggtggc
     4561 aggcaaccag ccaattattc caagtggact cttttcagga accagaacct taacaaccaa
     4621 tattgttctg gaaatggctt acgcatcagg tcagcatagg gaagccctta ttgcaacctc
     4681 agcagttctc tttttcctta ttctcttgat taatgcctac tttgcctact tgaaaggaaa
     4741 atcatcttat gagtaaatac ctgctaaaac ttctcgttta ttgtttttca gctttaacct
     4801 ttggctctct ctttttaatc attggtttta tcctcatcaa aggcttacct catctaagtc
     4861 tatccctctt ttcttggact tatacttctg agaacatttc ccttatgcca gcgattattt
     4921 ccaccgttat tctggttttt ggtgctcttc ttttagcttt gcccataggg atttttgctg
     4981 gtttttatct tgtggaatat acaaaaaaag attccctttg tgttaaaatc atgcgattgg
     5041 cctcagatac cttgtctggg attccttcca ttgtttttgg tctgtttggc atgctcttct
     5101 ttgtagtctt cttaggtttt caatactctc tgttatcagg aatcttaacc tcagttatca
     5161 tggtgttgcc agtcattatt cgctcaacag aagaagccct tttatctgtt agtgatagca
     5221 tgcgtcaagc aagttatgga cttggggcag gtaagttacg gactgttttt agaattgttc
     5281 taccagttgc catgccaggt attttagctg gagtgatact agctattggc cgtatcgttg
     5341 gtgaaacagc tgccctcatg tatacattag gtacctctac caatacgcca agtagtctca
     5401 tgtcttcagg ccgttctcta gccctacata tgtatatgct gtcaagtgag gggctacatg
     5461 tcaatgaagc ctatgctacc ggcgtgattt taattattac tgttttaatg ataaatactc
     5521 tatcaagctt attatctcgg aaacttgtga aaggagcttc ctagtatggg aacattttca
     5581 gtcagacacc tagacttatt ttacggggat tttcaagcct taaaaaatat ttcgattcaa
     5641 ttaccagaaa gacagattac tgccttgata ggcccatctg gttgtggcaa atcaactttt
     5701 ctaaaaaccc ttaaccggat gaacgatttg gttccttctt gccatattga aggccaagtc
     5761 ctcttagatg agcaagatat ttatagtagc aaattcaacc ttaatcagct acgtaagcgt
     5821 gtagggatgg tttttcaaca gcctaatccc tttgccatgt ctatctatga taacgtggct
     5881 tatggcccaa ggacacatgg tattcgagac aaaaaacaat tagatgcctt agtggagaaa
     5941 tctttaaaag gggcagccat ttgggaagaa gtcaaagatg atcttaaaaa gagtgccatg
     6001 tccttatctg gcggtcagca gcaacgcctt tgcattgcgc gagctttagc agtagaacct
     6061 gatattctgt taatggatga gccgacttca gccttagacc ctatctccac tttaaaaatt
     6121 gaagacctca ttcagcaact aaaaaaagat tatacgatta tcattgttac ccataacatg
     6181 caacaagctt cacgtatttc agataaaact gcttttttct taacaggaga aatttgcgaa
     6241 tttggagata ccgttgacgt gtttaccaat ccaaaagatc agcgcacaga agactatatt
     6301 tcaggacggt tcggataagg aaggaaaaac ctatgagaaa tcaatttgac ttagaattgc
     6361 atgaattaga acaatccttt ttaggactag ggcaacttgt ccttgaaaca gcttcaaaag
     6421 ccttactggc cttagcctcc aaagacaagg agatggcaga gctaattatc aataaggatc
     6481 atgctatcaa ccaaggtcaa agcgctatcg aattgacctg tgcccgtttg ttggccttgc
     6541 agcagccaca agtgtctgac cttcgatttg tgattagcat catgtcttct tgttcagacc
     6601 ttgaacgtat gggagaccat atggcaggca ttgccaaagc tgttttgcaa ctaaaagaaa
     6661 atcaactagc ccctgacgaa gaacagttac accaaatggg taaattatcc ctcagcatgc
     6721 tatccgattt attggttgcc tttcctttgc accaagcctc aaaagctatt agtattgctc
     6781 aaaaagatga acagattgac caatattatt atgccttatc aaaggaaatc attggactta
     6841 tgaaagacca agaaacctca attcccaatg gaacacaata cctttatatc atagggcatc
     6901 tggaacgctt cgctgattac attgctaaca tttgtgaacg cctagtctac ctagaaacag
     6961 gagaactagt ggatttgaat taattcaact aatccttaaa agagaagagt acgattaagt
     7021 gctctttttt atggttgtaa aaaagttcat ttgaccaatt taagcagtgt agatagtgag
     7081 gagctgtttc aattctatcg tgaacgaggg aatgctgaaa actttatcaa agaaaggaaa
     7141 gcaggattct ttggggataa gacagatagt tcgaccatga ttaagaatga agtacgtatg
     7201 atgatgggct gtctggctta taatctctac ctctttttaa agcagctagc tggtgatgaa
     7261 gtaaaggcct tgactatcaa gcgttttcga cgtctcttcc ttcatattgc cggaaaatat
     7321 gtctctactg ctagacgaca tattctcaaa ttctcaagtc tatatgccta ttcaaaacag
     7381 tttcaagcct tatttgatac aatctgccag ataaatctga tactccctgt tccatataga
     7441 gctagagggc aggggaaaac atgcctaaca gaataagtca ccttatttta aaaatcgagc
     7501 atcaaaccaa gggaggagtc tgcccttttt taggaaaaaa tcaagacaaa tctcctcaat
     7561 tatgtctcta acatcagaaa ttaagcaaaa tcaccagaag gacagtattt caactagctt
     7621 ttctggtaat ttttgaactg tgtagttcgt tagtgccaga tatgaataat ttgggatgat
     7681 aaatctttct tcctcaggta gcctatcata atactcttca aaaatcttat caaaacactc
     7741 tctttctttt gggcgatagt ttcatcttcg tatgtaggag tcctcatcaa gaaatacttc
     7801 aattctaggt attccttatc caactctata taacttggca tcaacttgta atcctcaacc
     7861 cccaaacgtt cagcgatata ttttaacttt gttagtgttg gtctggattc tccattttca
     7921 attctaatta attgacggat acttaattca gactcatcac cacaaaattc tgaacgactg
     7981 atttttttag ccaaacgtaa tcttttaatt ttttcgccaa actctcgcaa cctacaagaa
     8041 cctcctgagt tgtttacctc tattataagc atatactgaa tcaaactatc tatcagattt
     8101 cttctcactt taactaaaga ctaagagttt atcccttcat ctcggtcttt gtgtattttt
     8161 ccaccatacc ccagtaatgc aagtgcaaaa tcctctagaa tatgatagaa taatggaaag
     8221 aactctatca aggaggaaat catggaaaaa caaaccgtcg ccgtcttggg gcctggttct
     8281 tggggaactg ccctttcaca agtcttaaat gacaatggac acgaggtacg tatttgggga
     8341 aatcttcccg agcaaatcaa tgaaattaat acctatcata ctaacaagca ctactttaaa
     8401 gatgtcgttc tagatgaaaa tatcattgcc tacaccgact tagcagaaac attgaaagat
     8461 gtggatgcga ttttgtttgt tgtcccaaca aaagtgacac gacttgttgc ccaacaagtt
     8521 gcacaaacct tggaccataa ggctatcatc atgcacgctt caaagggatt agaacctgat
     8581 agccataaac gattatcaac tatccttgaa gaagaaattc ctgaacagct ccgcagtgat
     8641 attgtcgttg tttcagggcc tagtcatgcg gaagaaacca ttgtgcgtga cctaacttta
     8701 atcactgctg cttctaaaga tttacaaaca gctcaatacg ttcaggagct atttagtaat
     8761 cactacttcc gactttatac caatacggat gttatcgggg ttgaaactgc tggtgctctt
     8821 aaaaatatta ttgctgtcgg tgctggagct ttacatggtc ttggatttgg tgataatgct
     8881 aaggcagcca tcatcgctcg aggtttagca gaaatcaccc gcctaggggt agcactcggg
     8941 gccagtccat tgacctatag cggcttatct ggtgtgggag atttgatcgt aacgggaact
     9001 tccatccact ctcgtaactg gagagctgga gatgctctcg gacgaggaga atccctagct
     9061 gatatagaag ctaatatggg catggtaatc gaaggaattt caacgactcg agcagcctat
     9121 gaactagccc aagaacttgg agtctatatg cccattacac aggctattta ccaagttatt
     9181 tatcacggaa ccaatatcaa agatgccatt tatgacatca tgaacaatga atttaaagca
     9241 gaaaatgagt ggtcttaacc ctctatagaa aggattttta tgacatcaaa agttagaaag
     9301 gcagtcatcc ctgctgctgg actaggaact cgatttttac cagcaaccaa ggcccttgcc
     9361 aaagaaatgt tgccaatcgt agacaaacca actatccagt ttatcgtgga agaggctctc
     9421 aaatcaggta ttgaagatat tctagttgtc actggtaaat caaaacgttc tattgaggac
     9481 cactttgatt caaacttcga attggaatat aacctcaaag aaaaagggaa aacagatctt
     9541 ttgaagctag ttgatgaaac aactggcatg cgtctgcatt ttatccgcca aactcatcca
     9601 cgcggtctcg gagatgctgt tttgcaagcc aaggctttcg tcggaaatga accttttgtc
     9661 gttatgcttg gtgatgactt gatggatatc acagacgaaa aggctgttcc acttaccaaa
     9721 caactcatgg atgactacga gcgtacccac gcgtctacta tcgctgtcat gccagtccct
     9781 catgacgaag tatctgctta cggggttatt gctccgcaag gcgaaggaaa agatggtctt
     9841 tacagtgttg aaacctttgt tgaaaaacca gctccagagg acgctcctag cgaccttgct
     9901 attatcggac gctacctcct cacgcctgaa atttttgaga ttctcgaaaa gcaagctcca
     9961 ggtgcaggaa atgaaattca gctgacagat gcaatcgaca ccctcaataa aacacaacgt
    10021 gtatttgctc gtgagttcaa aggggctcgt tacgatgtcg gagacaagtt tggcttcatg
    10081 aaaacatcca tcgactacgc cctcaaacac ccacaagtca aagatgattt gaagaattac
    10141 ctcatccaac ttggaaaaga attgactgag aaggaataac aaaatcattt atataaagat
    10201 tagccacaca taaattaagt aaattctcta cttgaatcta cctatttaat aaaaactaat
    10261 gaaaacgcta tacttgtatt tgttttttca ttaaaataag agtagaataa attagtatag
    10321 taaaacaaaa aagcaccgaa tcggtgcgca ctttttcaag ttgtgtacgg acaaagcctt
    10381 attttaactt tgctatgttg tttcgaatgg ttccaaaata ataaataatt ttaaatttga
    10441 cttaactgtt ggagtagtca tggttaaatt aaatcaaccg agccgaacat aagttgttta
    10501 attttgtgga agctattaat aaaaatataa taagggagaa agataggtgt aattttaatt
    10561 ttaaagtaat tgcggacact atcaaagtaa aagattatgg agaacaaatt tgtagaattt
    10621 atcgaaaaca ataaaaaagt aatcatttca tcagttgcag ttggtgttgt attggtatta
    10681 gggtttggat ggtattcata taaccaacaa caagcagaac aacaagcaaa aattgtacaa
    10741 ttagaaaaag atagcaaatc agacaaagaa caagttgata aactatttga atcatttgat
    10801 gcatcttcag atgaatctat ttctaaatta aaagaactat ctgaaacttc acttaaaacc
    10861 gatgcaggta aagactatct taataacaaa gtcaaagaat catctaaagc aattgtagat
    10921 tttcatttgc aaaaaggttt ggcttatgat gttaaagatt cagatgacaa atttaaagat
    10981 aaagcaacct tagaaaataa tgtaaaagaa atcaataaac aaattgattt tatcaagaaa
    11041 gttgatgaaa ctttcaaaca aaaaaaattg gatgaaactg taaaatctct tacagatatt
    11101 gcagacaaat tccaaaaaca aattgatgtt ctgaagaaag aagaagaaca aaaagcatct
    11161 gacaaagcta aagaagataa gaagaaagaa gaatcaactt catctcaatc ttcaaatagt
    11221 tcatctcaag catcaagcag ttcttttagt tcatattctg gtaattcaga ttatgctcca
    11281 gaacaaacat acacagctga taatagccaa tcttattcag gttcaactgg tggagacaat
    11341 agtaactata aagcaccagc tgctacagac aacggaggaa atgatggcta tattcttggg
    11401 cacgtaactg gtgcagatgg atcgcaaaga gatttttatt ttaaccgttc aaacggagat
    11461 gttcgtgata caagcggcaa tcacgtagga aactttggag ggggcattac agattttaga
    11521 caacgttaat aactatttta gggctgtgtt gtttcgaatg gttccaaaac acattaaaag
    11581 ctactcattt tttaagtagc ttttttctta ttcaagttta catattagtt gtcacaaccc
    11641 cattcccttg tagaaaagca aaatggcgag tcctacgaac aagactaccg ctcctaatct
    11701 ctggctggta ttatacatcc gtttttctcc tctaactgga aagataactg ctagaaatgc
    11761 gccaccaact gcaccaccga tatggcctgc taggctgatt cctggaatca gaacacttcc
    11821 aataatgtta accacaaaaa gtgtcagata ggattgccct agctgttgga tataaggatt
    11881 gcgagttgca tagcgaagaa caataatcgc ggcaaatagc ccataaagag aggtagaggc
    11941 gcctgctgct aaggatttag gactaaatac aaaaacaaag agattgccca tcattcctga
    12001 taagagatag agaaaaaaga actgcttaga gccgaaaatc tcctctacct gccttccaag
    12061 ataataaagt gaaagcatat taacaatgaa atgttcccac ccaatatgaa caaaaatggc
    12121 agacaagaga cgccaaacct gctcgggaaa gaggcgaata gctggcccat acatggctcc
    12181 aaatcgaaat aatgtatctg ccctgtcaaa gtttccgcct gcagtgacca acattagtaa
    12241 aaataccaag gccgtcacta agaggaagaa actcgtcaca gggtaacgtc tatcaaagat
    12301 ttccttcatc aattaatacc tcctgaacag gaatatcatg gttttcaggt ataaagtcct
    12361 gaatttgaca aggatatatc gtactcaaag tacgaccaga aaaatgttcc aaatagcggt
    12421 cataatagcc tccaccgtat cctatccgat atcctttcgt cgtaaaagcc agaccaggaa
    12481 catgaatcaa atcaatctga gatgcatcca ccacttccac atctccctgt ggctccagta
    12541 aggcaaaggc agtttttacc aactgttgcg gatcatagac cacaaactcc atgcgcccct
    12601 tgggataagt tttgggtatt aaaaccttct tgccgtcctt cagcgcctgc tcaatcagtt
    12661 cccgcgtttg aaactcatga gaaaaagaga ggtaggttgc gatgaccttg gcttcttggt
    12721 agaagggatg gtgtaaaagc cgctcggtta aagcttggtc tatagcctgt ttttgctctt
    12781 gagatatagc cttcatttca tgcaagactt gcttgcgtaa ttccgatttc atagacaagc
    12841 cctctattct gctgccttct ttttcaggaa actagacacc gcagccaccc caatagctaa
    12901 gacttcttcc ttaggactca tttgagggtg atgaagagcg tagggactat cgatacccag
    12961 ccaaaacatc acgccatcaa cctttgaaag gagataacca aagtcctcgc ctgtcatagc
    13021 aggttcgata tcaatcaact cgattccgtc tttttcgtca aagaagtcca tcagttcacg
    13081 cgccaaggct ggattgttct caacaggtag gtatccacct tgtttgagtt ccacttcgac
    13141 ttccatatca aaggcagctg caaccccttc tgcaactgtt tttaccctct tttgcaccaa
    13201 gagactcatg tcctgtgtca aggcacgaat agttccatgt aaaaaagctg tttctgtgat
    13261 gacattgttg gtggttccag cttgaaaaac gccgaaggtc accactgctc cctcgattgg
    13321 gttgacattg cggctaacaa ctgactgcac ttgggtcaca aagtaactag ccgctaccaa
    13381 ggcgtcattg gcttcatgag gaaaagctgc gtggccacct ttgcctttga aacggatctt
    13441 cacctcgcaa gttcctacaa agagtgtatg agtattagtc gcaatctggc cgactttcaa
    13501 atctggacga acatggagac catagaattg gtttggcaac caatctccaa aagcaccgtc
    13561 ctcatacatg agcataccac cagcttcatt ttcttcagca ggctgaaata gaaagagcag
    13621 attattcttg ggttgctcct caagggcgcg ctcaagacag cctaaggcaa tggtcatatg
    13681 aaaatcatga ccacaggcat gcatgcgacc ttggtgttga gaagcaaaag gtagacctgt
    13741 ttgttcgacg ataggcaggc catcaatatc tgtccgccaa ccaatggttc gctccggctg
    13801 acttccctgc aggtagacca aaatccctgt ccgccaagta cgaatttgaa caaaatcctt
    13861 gcccgtagtc aatttctcaa tcacatccag caaataagcc tgagtcttga actcctccaa
    13921 gccaatctct ggtatctggt gtaaatctcg tctagtctga atcaaatcta acatctatct
    13981 gtcctccgat atagcagaaa gaggctggaa aaagggttcc gcctcttttt tacttttaca
    14041 attacaaggt acgaagcgca tcctctagcg ctgttttttg ttgggtttgg gcatcaattt
    14101 ctttgatgat acgagctgga acacctgcta ctaccacgtt ttctgggaca tcttgggtaa
    14161 cgatagctcc tgcagcgaca actgaaccac taccgatttg gactccttcg ataaccactg
    14221 cattagcacc gataagaaca ttgtctccga cacggactgg ttcagcacta gctggctcaa
    14281 tcacacctgc caaaactgca cctgcaccaa cgtggctatt ttttccaacg atggcacggc
    14341 caccaaggat ggcacccatg tcaatcatgg ttccagcacc gatttcagca ccgatattga
    14401 taacagatcc catcatgata acagcattgt caccaatttc cacctggtca cggataatag
    14461 cacctggctc gatacgagcg ttgatagcac gcttatctag caaaggaact gcagaattac
    14521 gagcatcttg ctcgacaaca taatcttgat tttctaccaa accttcaaga agcggagcca
    14581 cgtccttcca gtctccgaat aggacatttc ctagtttgac aacagagcta ggcacagcag
    14641 ttgcgagttg cccctcaaag gttactttga cactggtttt cttttcagca ttggcgataa
    14701 attggataat ttcttgagcg ttcatttttg tagcagtcat aggtgcctcc tggttcgtta
    14761 taatgatacc tattctacca aaaaaggcct caaatttgaa acctttttgt ctgtttttag
    14821 gtatgatttt ttagggatgt gagataaaac gtgctgtcgg taaaagcaag cccctaccga
    14881 tacaacctaa aaacactctt cacaactatc tccccgtgtt ttattgacta ttctagtata
    14941 gcacactttt agaattaaga aaagactttt tatctacttt ctttcgcttc ttctatagac
    15001 aaaaatatca tgggtaaaat aatcaaggct atagctagaa ggagggacca atccactact
    15061 aatcctaaga acaaaacact caagagagca gaagagagag gttcactggc actgataacg
    15121 gcaaccacca aaggagaaac caaggacaca gccttcatgg aaatgaaaaa agcaaaagcc
    15181 gttccaaaga aagcgataat gaggcaaatc aagatactcc aaatatcaag agtaaaggaa
    15241 agctgataaa ccggcgagag gacattgcta aacaaacctg ccaaaatcat cccccaccca
    15301 accgtaggaa caaaaccata acgcttagca aaaggttggg gcaagataac attaaacata
    15361 acacccatgg cactcagcaa acctgttata agagctagcg gcgtcatgga taactgagag
    15421 agatctccct ttgtcgccat caagcaaaca cccagcatgg caaccaaaac atagaaaaca
    15481 gcgctttttg acgctcgttt ttgataaacc aagcgattgt aaaagaggat aaagacaggg
    15541 ctaataaact gtaaaatagt tgctgtcgta gcatttgagt attctacaca gagatagaaa
    15601 aaatactgga ctgaaaaaat ccccaaaata gcataggcta aaaagggcag gtaatttttc
    15661 ttgtctcgcc aaatatctag cacttgcgat tttaattgta ttgcagacca aatgagtaca
    15721 atactccctg ccagtgtcaa acgcatagag gtaatccagc ccgaagacac ctgataatga
    15781 gtaaagaagt actctcctaa aattccacag attccccata ttaagccgga taggagcgaa
    15841 taaatttttc cgttaacaat ctttttctga tactgattca tacccttatt gtaacacgaa
    15901 aggaaaaaag tggcaatcca ttgattggcc acttcattta gagaattatc gtctcgccct
    15961 tgaagaagaa ggtcgtgtag tacttgagtt actgctatcg ctagaactac tacttgaact
    16021 gctggagctg gatggagttg gtagactccc cacaatacta gaccaagcat tctgataatc
    16081 cgcatcactt ccgccaatag caaagcgata acttgtcgct ggcgctcctg acttattagc
    16141 ccaatagctg gtaacagtcg aacctgtgac ctctacctct tttccttcaa cagaaacctt
    16201 ccctggtttt tgacctgttg atttcaagac ttccgatttc actacactag gatctaaagc
    16261 aaagcgctcg ttcccccaaa tgcttgggga agcttgctga atcgcattta ctagatgagc
    16321 catgtaatta gagttattag aataacctgc tctacgtgac aatgaatgat tatcatcatg
    16381 cccaatccag ccacctaggg ttaatctagg tgtcgaaagc atgagccaca tattttcgtc
    16441 ttggttggtt gtaccagtct tcccaatcca atctgcatta gccagagtag gatttaaaga
    16501 agtcaggtta gacttgaagg ttgttgtcac acgagaggat agaacttctc gtagcaatcc
    16561 ctgcataatc gtcgcagtag cttttgaata gacttgaacc ggtttatcct gatactcata
    16621 caccactcta ccatctgctg cttcaatctt tgaaatcaca tgcttctgat gataaactcc
    16681 attattagct aaggtctgat agccattggt atgctgggca actgtgactt caataccacc
    16741 acccattggc aagctctcaa taccgtactc aggaatctcg taacccatct tttccatata
    16801 acccttgaca tcaacaccat tttcacggag cagactatag gtccagtaag cagggatatt
    16861 ccatgagtag ttcagagctt ctcccaaggt catcattcct gttcccttgc tattagcata
    16921 cataatcgga ttgccattag caaagtttgt tggatagtta gatagaatcg tttcacttcc
    16981 catcaagccc tggtcaatag caataccgta ggccagcaag ggcttggtag tagaagctgg
    17041 cgaacgtttg gtatcaaagg catgattatt ttgattttct tgataattac gaccacctac
    17101 aaagcctaga atagcacctg tttggttgtc catcaagaca ttccctactt ctacacgacc
    17161 tgttccatcg tctaaaagat agccataatc agcaaccgca ctttgcatgg cagaatgaat
    17221 tttctgatct atggtagtag taatcttata accaccattt tcaatttcct tggctgccaa
    17281 atctcgataa aacttctgag ttgcctcatt tttcaactcc ttagcggaga cattgtctct
    17341 ctgagctaga tagtcataca tacgttcttg agcttctgcc aaagttgtaa agtataaata
    17401 gtctcgtgaa attcctgtaa ccgtgcccga tggtaaaaag tcctgtttaa ggtcataatc
    17461 cttgtactga gaatactcgt ctttgcttaa tgcacctgta cgatacatac tgtaaagaac
    17521 tgccttagcc cgtcttaagc caatttctag gtcttcatca ctcttcaact ccccagtatt
    17581 ttcataagga gagtaagtaa tgggactctg tggaagtcct gctaaaaatg ctgcttgagg
    17641 aacagtcaac tgactggcat ctacaccgaa aattccctca gctgcttgcc gagcccctgc
    17701 aatattctgt cccttattat ttcggccaaa gggagccaca ttgagatagg tcgttaaaat
    17761 ctcatcttta ttcatggcgc gttccaaggc aagagcatcc acaatctctg ccgccttacg
    17821 agccaaggtc ggcgcatccc caaccacctg ctgtttaatt agttgctggg tcaaggttga
    17881 acccccacta gaggaaccca aacctacaaa tttccccaag gtcgcacgaa tcaccgcctt
    17941 gggtactaca cccttatgtt ctttaaagtg ttcatcttct gtcgcaatga tagccttctt
    18001 cagattttcc gaaatttgct cagatgagat agaagtgcgc aacaaatcac tctctatgga
    18061 agcaatcacc gtcccgtccg aataggtaat ctctgaaata gaagagatgt ccttgacctg
    18121 attcaccaat tcttctgtct gaggcacccg aaccttgtca aataaggcca ctccgtaccc
    18181 caaagcaatc ccagctccca acattcctcc tagaaaaccg agtacaaaga gtaagttaaa
    18241 taaggctttt atactcagta aaatagctgg gaaaatggct gacttatcta aggttttaga
    18301 ttttttggta cttgaacctt tcttgccagg tctagctgat tttttatttt tttgtttttg
    18361 ctggaaaaat tccagcattt ttcgttttaa ttcatttaat tgattttgca tggatttcct
    18421 cactttatct attataccac aaaagggaaa ttttcaataa aatagccact ttcttcccta
    18481 ttctgctagg ctattgccca agtttgtgat acaataggta gaaacaataa ttttaaaaag
    18541 gagaaaaaac acatgcacat ttttgatgag ctaaaagagc gtggtttgat atttcaaacg
    18601 actgatgaag aagctttgcg taaagcccta gaagaaggtc aagtttctta ttatactggc
    18661 tacgatccaa ctgctgacag ccttcaccta ggccaccttg tcgcaatctt gacaagtcgt
    18721 cgcttgcaac tagcaggtca caaaccttat gcgctcgttg gcggtgctac aggtctcatc
    18781 ggagatccgt ccttcaaaga tgctgaacgt agtctccaaa caaaagacac agtagatggc
    18841 tgggtcaagt ctatccaagg acaactttct cgttttcttg actttgaaaa tggcgaaaac
    18901 aaggctgtca tggtcaacaa ctacgactgg tttggcagca tcagcttcat tgacttcctc
    18961 cgtgatattg gaaaatactt cacggtcaac tacatgatga gtaaggaatc tgtaaaaaaa
    19021 cgaatcgaaa caggaatttc ttacactgag ttcgcttacc aaatcatgca agggtacgac
    19081 ttcttcgtcc ttaaccaaga ccataatgtc actcttcaaa tcggtggttc tgaccagtgg
    19141 ggaaatatga cagctggtac cgaattgctt cgtcgtaaag cggacaagac tggtcacgtt
    19201 atcactgttc cactaatcac agatgcaact ggtaagaaat ttggtaaatc agaaggaaat
    19261 gccgtctggc tcaatcccga aaagacttct ccatacgaaa tgtaccaatt ctggatgaac
    19321 gtgatggacg ctgacgctgt tcgcttcttg aaaatcttta ctttcttgtc acttgatgag
    19381 attgaagata ttcgtaaaca atttgaagca gcgccacacg aacgcttggc tcaaaaagtc
    19441 ttggctcgtg aagttgttac acttgttcac ggagaagaag cctacaaaga agcacttaac
    19501 atcactgagc aactctttgc aggaaacatc aaaaaccttt ctgtcaaaga gctcaaacaa
    19561 ggacttcgtg gtgtgccaaa ctaccaagta caggcagacg aaaacaacaa tatcgtggaa
    19621 ctgctcgtct catctggtat agttaactca aaacgccaag cccgtgaaga cgtccaaaac
    19681 ggagccatct acgtaaacgg cgaccgcatc caagagcttg actatgtctt gagtgacgct
    19741 gataagttag agaatgaact gactgttatc cgtcgtggga agaaaaaata ctttgtattg
    19801 acttactaaa ctattcaaca tttatctata aacaaaggag ttagcctcga gaaaggtaac
    19861 tcctttttgc tgttaataac tctcatctat ctatttttaa tagacaggct acgcaggaca
    19921 atgcgcaagg ttgttagatt atgtaagata gagagatttg aaggactgag ccaattaaat
    19981 aagccgaagc caatcaaact actatttacg acaacggtat cttgaatatt tttcttgatg
    20041 agtgtttgca aagatgatga taacgaatcc aactcttgga agaaatccaa acgattatct
    20101 aacaataaga tatcactcat ctgcttagaa atatctgcac tctcattcat caccacaccg
    20161 atatctgata gagttaaagc cgctgagtca ttcaatccat ctccaaccat caaaatagtg
    20221 tgacctgctt tctgcagttt ctctactaac tcaaatttcc catcaggttt caagtctgta
    20281 tagacctgat caaagggcaa atctttgact aattcctctg tcctagtcaa ggtgtctcct
    20341 gttgccagaa tcaatttttt cccctgtgcc ttaagtttat ccaaggctgt ttttgcttct
    20401 tttctcaaag gagtatgaat gcagaacatt ccaatcaatt cattttgata agccaagaat
    20461 aagagattgt agtgactctt gtactcttca attaaagcat tttgttctga actgatatga
    20521 atctgctcat cctgcatcaa gacataattc ccaataagaa ctggttggcc atctatatga
    20581 gatttgatcc ccttgcttgc gatatattgg agtttcccat gcatttcctc atgttcaatt
    20641 ccctctatct cagcttgctt gacgatggca ttagcaatag gatgataaat gtgttcctca
    20701 agacaggcac tgattctgag aatatcttcc tcactatagt ctccaaaagg taacaccttt
    20761 tcaactatag gataactagt tgtgattgtt cctgtcttat caaacaagaa agtatcaact
    20821 tccagatatt tctccagaac atctccatcc ttaatcacca tttcacggtt caacccttcc
    20881 ttgataactg tcaaataagc tacaggagta gagattttca aagcgcagga gaaatcgacc
    20941 aataggaaag aaatagcctt agaaaaagaa cctgtcaata ggtaagtcag cccagacccc
    21001 aagaaattat atttgacgac tttatccgcc atcttgatga aatagcgttg tttcgttttc
    21061 ttgttttctt cagatttctt catcaactca atcagctgta aaatacggct gttcatctga
    21121 ttatctgtta cacgaatgcg taactctcca gtttctaata ctgtatttgc acaaaccaaa
    21181 tcagactctc ttttttcaac tggaaaactc tctcctgtca aggaactttc gttgaccata
    21241 cctaaacctg aaactacttg tccatcaaac agaatttcat ttccttgaga taagatcaag
    21301 acatctccta tttgaacatc ggaactcttg atactaacaa ccgtatcgcc ctgtactagg
    21361 aatacatcgc tctcttttgc aagaagactc tgttctaaat ctgttgcagt ttttttcaag
    21421 gaccactgat ctaaatgatt ccccaaatca agcataaaca tgatattgct agctgtcttg
    21481 gattggttca taaacaagga caataaaata gccgaacagt ccaagacttc catcgttagt
    21541 tccttacgcg ctagtgtttg ataggcttct ctaatataac ccaaagcctg ataacaagtc
    21601 catatatagc gaataggata cggcacaaaa ctacgaaaaa gtacacgctt aaccgctgca
    21661 cctgaaacaa tagaataagc actctcttct ctacgaatgg gaagagtcat caactcagaa
    21721 actttccctt tatcaattct ttttaaaaag gcttctgcat tatctaatac agaaaagcct
    21781 tcttttatgc gtagagtaaa gtgctgttga tccatgtaaa actggataga ctcaatcccc
    21841 ttttcatctc tcgccaagga acgaagatag tcttgaatat ccaaggtaag tgaaaaagaa
    21901 gatgatagtc ggatatgttg gtatcctcta tgtagcactt taaaagacat attattcacc
    21961 tataaggcta tctaattgct cttctttttt ctcttgctcg tacaaatatt tggcatcttg
    22021 caagacatcg tctccatgtt gcttcacaac agaaacagat gcatctagct cgtctttcaa
    22081 cttgtaagcc ttagccaaag ctttagaata acctttttta gcttccttac ttgctaagat
    22141 tttcaaacca agggtaccaa atgcgacacc acccaaaaat aatgaagatt ttttcgcaac
    22201 ttttgcaacg gttaatactt cttttaacat acttatttcc tccttatcat tattatatag
    22261 caatttagat ataaaagcaa tttcattcta taaattggag aattagtttt atttctactg
    22321 aatctcccat ctacttattc ctaaagttgc tttcatttgc ctcttttgat acacttaaac
    22381 tatgaataca aatctcaagc ccaaacttca gcgttttgct tctgcgactg cctttgcctg
    22441 tcctatctgt caagaaaatc tgactctgtt agagactaat ttcaagtgct gcaaccgtca
    22501 ttcttttgac ttggcgaaat ttggctatgt caatctagca cctcaaatca agcaatctgc
    22561 taactatgac aaggaaaatt ttcaaaaccg tcaacaaatc ctagaagccg gcttttacca
    22621 agctatctta gatgctgtat ctgacttgct tgcaagctca aaaactacca caacaatttt
    22681 ggatatcggt tgtggtgaag gattctattc tcgcaaacta caagaaagtc actctgaaaa
    22741 aactttctat gcctttgaca tctccaaaga ttcagtccaa atcgctgcta aaagtgaacc
    22801 caactgggca gtcaattggt tcgttggcga cttggcacga cttcctataa aagacgctaa
    22861 catggatatt ctgcttgata tcttctcacc tgccaactat ggagaatttc gtcgcgtttt
    22921 atccaaagac ggtatcttga taaaggttat cccaactgaa aatcacctca aagaaatccg
    22981 tcaaagagta caggaccagc tgacaaacaa ggagtattct aaccaagata tcaaggagca
    23041 tttccaggaa cactttacca tcctatctag tcaaactgcc tctctgacta agactatcac
    23101 agcagaacaa ctccaagccc tactcagtat gactcctctc ctctttcacg ttgaccagag
    23161 caagattgac tggagccaac tgacagagat taccatcgaa gcagagattt tggttgggaa
    23221 agcattctaa actagacttc ccaaaggtat aaaacttacc gaaaatcttc aatattataa
    23281 aaacgcataa gaacaggtac acaaacctta atcttatgcg ttttgttata gtttccatac
    23341 acattaaggg gaaatagttg aaatcagttc tcttaataac cattgaatac catatactac
    23401 atttacccca aatatgatat aggccgtata aatcaagtat ttcgattttt cccgcctcaa
    23461 agaatagatc ttatacaaaa taaataaatt taaaataata aataatagag acaaaatctt
    23521 cctccaaaat caatattaaa agtagccagt caatcatagt tctaatcttt attttcgatt
    23581 cgaaattaca aacttatcaa tgaacaataa gtgatataag gccagtacca gaccccaaac
    23641 gctaccacga aaagagaatt cttgatgatt gagagtaaac aaatcatggt taccaatata
    23701 gaggcaggtc aaaataacaa ataaaatcca aaataaatcc gtccatttat attttgaaaa
    23761 atattttttt aacataatag catatttttt tgactataat aacagtatat gataaaatgt
    23821 aagcagatac aaataaaaag gagaaaagct catgaacaaa ttaatgaaat ttatttcggt
    23881 ttttttgacg tcaattgtgt taattgtatc agcgattcca agtgtttcag ctgtatacgc
    23941 ttctgaacaa gtatcacaaa ttgaaacaaa tatggaactt caacctgtca cttctctaac
    24001 agaagaacaa atcaatacac ttgcaaacga aatccaatct tttcatccag acgtctcaca
    24061 acaatggatc aaagaagtaa ttaaccgaca attacaaggc gattatacaa tcccacctac
    24121 atactctcca tttagagcag cttggcaagg tattacagtt aatcaaatgg gtgctctatt
    24181 agatactgca atagctttag cattaggagg aactactgca ggccttgcaa atctaattaa
    24241 agtaaaagga aaacatgcag caaaaagtgc tattcgttca gcaatttcta gatatctagg
    24301 tagttggttt gtaaatgatg ttgctttaga attcgctatg aatttattat caccggggac
    24361 ttatttagca caattatggg ataaaaatga tgccattcct aacaacggaa ggattaactt
    24421 ttaatcatga gatatacaat aaaattaatt gggtataacg tattttcgtt gtttatattc
    24481 tttatcttat caatgttgtt taaagttccc tttaggtggt ggatcagcat tgcaatgacg
    24541 acttcgtcgt acattgtata taattactta aagaaaaaga gagaaaagga atgatcttat
    24601 accagatcat tccttttctg ctttctgtaa atccctcgga gtgtgtttgg cgctttgata
    24661 cgaagtgtca aagctgtata aacgttacta tttccaaaaa agtaacagaa aattcctgct
    24721 ttgtaggact gctttgggtg agtaatagac atgtcgactc accctatctc ctgatggcga
    24781 aaagaattta gcaatggtgc aagttgttct gaactcgaga aaaaacatgc cgaaatcgaa
    24841 gaaaagcgtg cagaacttga agcgaagaag caagaaatgt tgaatcgctt ggataaatag
    24901 aatttagaaa acagaaaaac taaaaagaat gtagggttta tttccctaca ttcttaaaat
    24961 aacttagtac ataaatgaca atgctgccac tgccgtcaat attgcaaaaa ctattttcca
    25021 aattttttta ttttttccaa aaatcttatc aggtaacaag cttattacaa gaaaggtaat
    25081 aaacaacacc aatttaagtg tgtatatcat aaaaacacct tctttcctac aattatatta
    25141 taatacttta tgtaagcgaa tacaagagat gtgaggtaac caactacgaa aaaatataag
    25201 gctgaagaca gtaaaaacca gcatttaaag ccttcactgt atctaggatt tccctatttt
    25261 tagacaagat tgacccaaat ccacagcatt taaaaaagcg aatttcaatc gaaactcgct
    25321 tttttacaaa atgtattagt ataaatttgt atcttatact caatgaaaat caaagagcaa
    25381 actaggaagc tagccgcagg ttgctcaaag caccgctttg aggttgcaga taaagctgac
    25441 gtggtttgaa gagattttcg aagagtatta gttcaagtgc cagatgtctt cattatactg
    25501 agcgattgta cggtcagatg agaagaatcc tgctttagaa atgttaacga tgactttatc
    25561 caaccatgcg tcacggtctt cgtagtcagc aagcatttgc tctttgactt tgatgtagtc
    25621 ttccaagtca agaagagtca tgaaccagtc tttgttgatc aattcattgt aaagacgttc
    25681 caagcgctct ttgtttccag ctgcaagaac tgcatcacta acgatgaagt caaccaatgg
    25741 tttgatagct tcacgagcgt agaattcgct tgatttgtaa gctgcttttg cgtaaaggtc
    25801 gataacagtt tctgaatctt caccgaagat gtagatgttt tcttctccaa ccaactcagc
    25861 gatttccacg ttagcaccgt ccatagtacc aagtgtcaaa gctccgttca acatgaattt
    25921 catgttacca gtacctgaag cttctttaga agcaagtgaa atttgttctg agatatcaca
    25981 tgctgggata aggaaacttg ctgcagtaac gttgtagttt tcaaccataa ctacttgcaa
    26041 gtgtggagct actgctggat cgttagcaat aacttctgac atgcaaagga ttaaatggat
    26101 aatgtcttga gcgattgtgt aggctggagc tgctttacca ccaaagaaga ttgtgattgg
    26161 acgagcaggg atgttaccag ctttgatgtc aaggtatttg tggatcacgt acaaagcgtt
    26221 catttgttgg cgtttgtact cgtgaagacg tttgatttgg atatcaaaga tagaatttga
    26281 attgatttcc acaccttggt gttctttcaa gtgacgagcc aatttacgtt tgttgtgagc
    26341 cttgatgctt tccaattttt ctttgacagc tgctttgtct tcataagaca aaagtttttc
    26401 aagctcatct gcttcatggt gccaaccatc tccaagaatc tcatctaagt agtgagacaa
    26461 tcttgggtta gcatgcataa gccaacgacg gaaagtgata ccgtttgttt tgttgttgaa
    26521 cttttctggg taaaggtcgt agaaggcttt caactcagaa tttttcaaga tttcagtatg
    26581 gagtgctgca accccgttaa cactgtatcc gtagtggata tccatgtgag ccatgtgaac
    26641 acgtccgctc tcatcgatga tttgaacagc tggatctttg tactctgcct tcacacgacg
    26701 gtccaattct tcgatgattg gtaccaagtg aggaaccact tcttgcaaga attcaagagg
    26761 ccatttttca agcgcttcag caaggattgt gtggttagtg taggcagtca tgctacgaac
    26821 aattgagatt gcttcgtcaa gctcgatacc acgtgcagtt aaaagacgaa tcaattcagg
    26881 aatcaccatt gatgggtgag tatcgttgat ttggacaact gcgtagtcag caaggtcatg
    26941 caagttgctt cctttttcga ttgcttcgtc gatgatcaat tgcgcaccgt ttgaaaccat
    27001 gaagtattgt tggaagatac ggagcaattc accttgacgg tcactatcat ctgggtaaag
    27061 gaagagagtc aagttgcgag cgatatctgt cttgtcaaag ttgataccat ctttaataat
    27121 agaagaatca actgaatcca agtcaaacaa acgcaagcgg tttttagtcg ctgtttcata
    27181 accagtaaca tcaatatcgt aaagagttga tgtcaaagta aagtctgcaa atggtacttg
    27241 gtagctacgg cttgagcaaa ccaaccagtt ttgctctgtc aaccatgcat ttggaattgt
    27301 ttcttgttgg ttgtttttaa gaacttgttg gaaaagacca aagtggtagt taagaccaac
    27361 accgtcacca ttcaaaccaa gagtagcaat tgagtcgata aagcaggcag ccaaacgtcc
    27421 caaaccacca ttaccaagag atggttccaa ttcaacttct tcaacttcga tcaagtcttt
    27481 acctgcagct gcaagttctt ttttaacatc gtcgtaaaga ccaaggttaa tcaagttgtt
    27541 tgacaagagt ttaccaatca agaactcagc tgagatgtag taaacttttt tcttaccagt
    27601 gttgactggt ttttggctgc ttgcaagctt gctgtagtta agaagagcaa ggtaaagctc
    27661 ttcattgcta cattctgcaa tggttttatt gtaacgattt tgtacaaatt cttgtagtga
    27721 taacatgttt agttgtctcc tgattattgt cttatttctt taaatctacc aaattttcat
    27781 taattcggcg ataaattgtt gtcaagtcaa gcaaaccttc ctcgacagct ggtgtcaatt
    27841 gatcttcagt catacgccaa gaccagtttc caccaagggt agatgggaag ttcatacgag
    27901 ctgcctcatc caattctagt aaatcttgca tagtcgcaat tgccataaag ctaactgatg
    27961 aaaatactgt acgaagcata gcgtgtacca ctgtttcgta ttctttacgg ttcgtgtaac
    28021 gagccatgta ctcacgagtc gcatcatcaa tctcattacg gtaccaacca agaaccgtat
    28081 tgttatcgtg tgttcctgtg tacataactg agttagcagg tgccaagtgt gggctatcaa
    28141 tgctttcgtc ttctgggttg aaggcaaatt gaagaatctt cattcctggg aagccagtac
    28201 gttcacgcaa ttcgatcact tcatctgtca tgaagccaag gtcttctgcg atgatgttta
    28261 gctcaccaag ttcttcctta acggctgcaa aaagcttgta gcctggacct ttcacccact
    28321 caccaggtgc tgctgtatcg gaaccagcag ggatttccca ataagattcg aagccacgga
    28381 agtggtcgat acgaacgata tcgtagattt tgaagctttc acgcaagcgt tcaatccacc
    28441 atttgtagcc gtctttgtcc attgcttccc agtcatagat tgggttaccc caaagctgac
    28501 cagttacaga aaactcatct ggtggacatc ctgcgataca agtagcctta ccattgacat
    28561 ctgttttgaa gagatgtgga tttgcccaca tatcacttga atcttccgct acgtagattg
    28621 gcatgtcccc aacgatttcg atgtggttgt cgttagcgta agctttcaat ttcaaccatt
    28681 gttggaagaa gaagtattga gtcacacggt ggtaaaccaa cttgtctgcc aattgctcac
    28741 gatagctttc aagtgctgaa gctttacgag cacgagcatc tgcatctggc cattcagtcc
    28801 aagcaagatt gtcaaaatgc tctttgatag ccatatactc agcaaagagc tcaagccatg
    28861 attggttgtc ttgagcaaat ttctcaaaat ctttaacata tccgacttca aagaaacgct
    28921 tcaccgcttt ttctaaaaga ggacgacgtg catagtagat tttagcatag tcaacttcag
    28981 acgcatcgct accaaagtca actccttcaa ggtcacttgc ttccaacaaa ccttgctcca
    29041 ccaagatatc taaatcgata aaatgagtgt ttcctgcgaa ggctgagaaa gattggtaag
    29101 gagaatcccc gtaactagtt gctcctaatg gaaggatttg ccagtaacgt tgttttgtac
    29161 ggaccaagaa atcaacgaag tcgtaagcac tttgaccaaa tgatccgatt ccgtaagctc
    29221 ctggaagaga agagatgtgc atcaacacac cactttgacg ttttttcata atagcacctc
    29281 gtgtgttaaa ataatggaac gttgcgtatt tttcagacgc aaacgtttgc gttacttata
    29341 agtatactcc ttttcaagca taattgcaag cgtttttaaa aaactttttt gattattttt
    29401 aaggagacta actcatttta gcaaagataa cttaaaacta tctaatccta aggtttgact
    29461 ctcacgagac agtatacaaa gtacaaaacc tccttaggga gcttgaattt atatgcaaca
    29521 aagcacaaac gtctatagaa aatagatata gattagaaat agggaggtag cccctcctga
    29581 tttccctctt tagacagatt ccatatattt ttattaaaaa tactgtattc ttatctattt
    29641 catacttttc ttctattaaa atgcaaaatt atgctatcaa atcaagctta aaaatttttt
    29701 aaaattttta caaaaaatac ttgcaaccgt tttctattta tgctatacta agctcataaa
    29761 ggaaaacgtt tgcgtttcct tatcaataaa acttgctatt ctttgggagg aatacactat
    29821 gtcatctaaa tttatgaaga gcactgcggt gcttggaact gttacacttg ctagcttgct
    29881 cttggtagct tgcggaagca aaactgctga taagcctgct gattctggtt catctgaagt
    29941 caaagaactc actgtatatg tagacgaggg atataagagc tatattgaag aggttgctaa
    30001 agcttatgaa aaagaagctg gagtaaaaat cactcttaaa actggtgatg ctctaggagg
    30061 tcttgataaa ctttctcttg acaaccaatc tggtaatgtc cctgatgtta tgatggctcc
    30121 atacgaccgt gtaggtagcc ttggttctga cggacaactt tcagaagtga aattgagcga
    30181 tggtgctaaa acagacgaca caactaaatc tcttgtaaca gctgctaatg gtaaagttta
    30241 cggtgctcct gccgttatcg agtcacttgt tatgtactac aacaaagact tggtgaaaga
    30301 tgctccaaaa acatttgctg acttggaaaa ccttgctaaa gatagcaaat acgcattcgc
    30361 tggtgaagat ggtaaaacta ctgccttcct agctgactgg acaaacttct actatacata
    30421 tggacttctt gccggtaacg gtgcttacgt ctttggccaa aacggtaaag acgctaaaga
    30481 catcggtctt gcaaacgacg gttctatcgc aggtatcaac tacgctaaat cttggtacga
    30541 aaaatggcct aaaggtatgc aagatacaga aggtgctgga aacttaatcc aaactcaatt
    30601 ccaagaaggt aaaacagctg ctatcatcga cggaccttgg aaagctcaag cctttaaaga
    30661 tgctaaagta aactacggag ttgcaactat cccaactctt ccaaatggaa aagaatatgc
    30721 tgcattcggt ggtggtaaag cttgggtcat tcctcaagcc gttaagaacc ttgaagcttc
    30781 tcaaaaattt gtagacttcc ttgttgcaac tgaacaacaa aaagtattat atgataagac
    30841 taacgaaatc ccagctaata ctgaggctcg ttcatacgct gaaggtaaaa acgatgagtt
    30901 gacaacagct gttatcaaac agttcaagaa cactcaacca ctgccaaaca tctctcaaat
    30961 gtctgcagtt tgggatccag cgaaaaatat gctctttgat gctgtaagtg gtcaaaaaga
    31021 tgctaaaaca gctgctaacg atgctgtaac attgatcaaa gaaacaatca aacaaaaatt
    31081 tggtgaataa aaaatttgtt caaggggggt ggaaatcaaa tccccctttg aatttatcaa
    31141 tagagacaca aataatttag ctttcttata aaaaagtagt atcctatgaa aggagttaat
    31201 atggaaaagc aacaacctag taaagcagcc ctgctgtcta tcattcctgg gttaggacag
    31261 atttacaata aacaaaaagc caaaggtttt atcttccttg gtgtaaccat cgtatttgtc
    31321 ctttacttcc tagcacttgc aacccctgaa ttgagcaacc tcatcactct tggtgacaaa
    31381 ccaggtcgtg ataattccct ctttatgctg attcgtggtg ccttccatct aatctttgta
    31441 atcgtttatg tactctttta tttctcaaat atcaaagatg cacatacgat tgcaaaacgc
    31501 attaacaatg gaattccagt tccacgcaca ctcaaagaca tgatcaaagg gatttatgaa
    31561 aatggcttcc cttacctctt gatcattcca tcttatgttg ccatgacctt cgcgattatc
    31621 ttcccagtta tcgtaacctt gatgatcgcc tttaccaact acgacttcca acacttgcca
    31681 ccaaacaagt tgttggactg ggttggtttg accaacttta caaacatttg gagcttgagt
    31741 accttccgtt ctgcctttgg ttctgttctt tcttggacta tcatttgggc tttggcagct
    31801 tctactttac aaatcgtaat tggtatcttc acagctatca ttgccaacca accatttatc
    31861 aaaggaaaac gtatctttgg tgttattttc cttcttcctt gggctgtccc agccttcatc
    31921 actatcttga cattctcaaa catgtttaac gatagtgtcg gtgctatcaa cactcaagta
    31981 ttgccaatct tggctaaatt ccttcctttc cttgatggag ctcttattcc ttggaaaaca
    32041 gacccaactt ggactaagat tgccttgatt atgatgcaag gttggctcgg attcccatac
    32101 atctacgttt tgactttggg tatcttgcaa tctattccta acgaccttta cgaagcagct
    32161 tatattgacg gtgccaacgc ttggcaaaaa ttccgcaaca tcactttccc aatgattttg
    32221 gctgttgcgg cacctacttt gattagccaa tacaccttca actttaacaa cttctctatc
    32281 atgtacctct tcaatggtgg aggacctggt agtgtcggag gtggagctgg ttcaaccgat
    32341 atcttgatct catggatcta ccgtttgaca acaggtacat ctcctcaata ctcaatggcg
    32401 gcagctgtta ccttgattat ctctatcatt gtcatctcaa tctctatgat cgcattcaag
    32461 aaactacacg catttgatat ggaggacgtc taagatgaat aactcaatta aactcaaacg
    32521 tagactgact caaagcctta cttaccttta cctgattggt ctatcaattg taattatcta
    32581 tccactgttg attaccatta tgtcagcctt taaagcaggt aacgtctcag cctttaaact
    32641 agatactaat atcgacctca attttgataa ctttaaaggc ctcttcactg aaaccttgta
    32701 cggtacttgg tacctcaaca ctttgattat cgccttaatt accatggctg ttcaaacaag
    32761 tatcatcgta cttgctggtt atgcttacag ccgttacaac ttcttggctc gtaaacaaag
    32821 tttggtcttc ttcttgatca tccaaatggt gccaactatg gccgctttga cagccttctt
    32881 cgttatggcg cttatgttga acgcccttaa ccacaactgg ttcctcatct tcctctacgt
    32941 tggtggtggt atcccgatga atgcttggct catgaaaggc tacttcgata cagtgccaat
    33001 gtctttagac gaatctgcaa aactagacgg tgcaggacac ttccgccgct tctggcaaat
    33061 tgttctacca cttgttcgcc caatggttgc cgtacaagct ctctgggcct tcatgggacc
    33121 tttcggggac tacatcctct ctagtttctt gcttcgtgag aaagaatact ttactgttgc
    33181 cgtaggtctc caaaccttcg ttaacaatgc gaaaaacttg aagattgcct acttctcagc
    33241 aggtgctatc ctcatcgccc ttccaatctg tattctcttc ttcttcctac aaaagaactt
    33301 tgtttcagga cttacaagtg gtggcgacaa gggataattt atccccgcca ccctttttca
    33361 ttttatactc ttcgaaaatc tcttcaaacc acgtcagctt tatctccaac ctcaaagttg
    33421 tgctttgagc aacctgtggc tagtttgcac tttgattttc attgattatt agcaattgtc
    33481 actgtaaata atatccttgt agcaagcaat ttttctccta gacttgaaat aaagcgcatt
    33541 tctctatata ataatactca tatagaaaac accttttaga aagataccta tgcttccata
    33601 tccattttcc tatttttcaa gtatttgggg gtttcgtaag cccctgtcca aacgtttcga
    33661 gctcaactgg tttcaacttc tctttaccag tatcttcctt atcagcttgt ctatggtacc
    33721 cattgctatc caaaacagct cccaggagac ctatccgcta gaaactttta tcgataatgt
    33781 ctatgaacct ctgacaaatg aggttgtcca ggatctctct gaacatgcta caattgtcga
    33841 tggcacatta acttatactg gaacagctag tcaaacccct tctgttgtga ttggtccaag
    33901 tcaaatcaag gaattaccta aggacttgca actgcatttc gatacaaatg agctagtcat
    33961 cagcaaggaa agcaaggagc tgacccgcat ctcttaccga gccattcaga ctgagagttt
    34021 caaaagcaaa gacagcttga cccaagcaat ttctaaagac tggtaccaac aaaatcgtgt
    34081 ctatatcagc ctcttcctag ttctcggtgc gagcttcctc tttggtttga atttctttat
    34141 cgtctctcta ggagctagtc ttctccttta tatcactaag aaatcacgcc tcttttcatt
    34201 tagaaccttt aaagagtgct atcactttat cttgaactgt ttaggattgc cgactctgat
    34261 tacacttatt ttgggattat ttggccaaaa tatgacaacc ctgattactg tacaaaatat
    34321 tctttttgtt ctgtatctgg tcactatctt ttataaaaca catttccgtg atccaaatta
    34381 ccataaatag gagattttta tgcccgttac gattaaagac gtggccaagg ctgctggtgt
    34441 ttcgccttca accgtaaccc gtgttattca aaataaatca accattagcg acgaaacaaa
    34501 aaaacgcgtt cgcaaagcta tgaaggaact caactaccac ccaaacctca acgctcgtag
    34561 cttggtaagc agctatactc aggttatcgg attagttctt cctgatgact cagacgcctt
    34621 ctaccagaat cctttctttc catcggttct acgtggcatc tctcaagtcg catctgaaaa
    34681 ccactatgcc attcagatag caacagggaa agatgagaag gagcgtctca acgctatttc
    34741 acaaatggtc tacggcaagc gtgtagatgg gctaatcttt ctctatgccc aagaagaaga
    34801 ccctctcgta aaactcgtcg cagaagaaca gttccccttc cttatcttag gtaaatctct
    34861 atctcctttc atcccacttg tcgacaacgg caatgttcaa gctggttttg atgcgactga
    34921 atatttcatc aaaaaaggct gcaaacgcat tgcctttatc ggaggaagta aaaagctctt
    34981 cgtgaccaaa gaccgtttaa caggctatga acaggcgctt aaacattaca aacttaccac
    35041 tgacaacaat cgcatctact ttgccgacga gtttctggaa gaaaagggct ataaatttag
    35101 caagcgatta ttcaagcacg atccacaaat tgatgctatc atcacaaccg atagcctcct
    35161 agctgaaggt gtttgtaact atattgccaa acaccagctg gatgtccctg ttctcagctt
    35221 tgactcggtt aatcccaagc tcaacttggc agcctatgtc gatatcaata gtttagagct
    35281 tggtcgtgtt tcccttgaaa ctattctcca gattattaat gataataaaa acaataaaca
    35341 aatttgttac cgtcaattga tcgcccacaa aattatcgaa aaataagaga ctgggcaaag
    35401 agtcgttaaa agcaaaaacg catactatca ggtattgaaa aaacttgata ctatgcgttt
    35461 ta
//
LOCUS       DAVBOM010000019        34124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBOM010000019 DAVBOM010000000
VERSION     DAVBOM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.019"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(21..833)
                     /locus_tag="VQ878_000971"
     CDS             complement(21..833)
                     /locus_tag="VQ878_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3095321.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            1023..2441
                     /locus_tag="VQ878_000972"
     CDS             1023..2441
                     /locus_tag="VQ878_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET3095322.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            2494..3201
                     /locus_tag="VQ878_000973"
     CDS             2494..3201
                     /locus_tag="VQ878_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3095323.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            3297..4277
                     /gene="folP"
                     /locus_tag="VQ878_000974"
     CDS             3297..4277
                     /gene="folP"
                     /locus_tag="VQ878_000974"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET3095324.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFVLEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEEMMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            4279..5601
                     /locus_tag="VQ878_000975"
     CDS             4279..5601
                     /locus_tag="VQ878_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3095325.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLALLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            5582..6136
                     /gene="folE"
                     /locus_tag="VQ878_000976"
     CDS             5582..6136
                     /gene="folE"
                     /locus_tag="VQ878_000976"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET3095326.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            6179..6991
                     /gene="folK"
                     /locus_tag="VQ878_000977"
     CDS             6179..6991
                     /gene="folK"
                     /locus_tag="VQ878_000977"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET3095327.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7036..7353)
                     /locus_tag="VQ878_000978"
     CDS             complement(7036..7353)
                     /locus_tag="VQ878_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET3095328.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            7710..8156
                     /gene="rplM"
                     /locus_tag="VQ878_000979"
     CDS             7710..8156
                     /gene="rplM"
                     /locus_tag="VQ878_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET3095329.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ878_000980"
     CDS             8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ878_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET3095330.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(8829..9251)
                     /locus_tag="VQ878_000981"
     CDS             complement(8829..9251)
                     /locus_tag="VQ878_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3095331.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            9398..9574
                     /locus_tag="VQ878_000982"
     CDS             9398..9574
                     /locus_tag="VQ878_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095332.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9976..12189
                     /locus_tag="VQ878_000983"
     CDS             9976..12189
                     /locus_tag="VQ878_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET3095333.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12411..12887)
                     /locus_tag="VQ878_000984"
     CDS             complement(12411..12887)
                     /locus_tag="VQ878_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET3095334.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13110..16313
                     /locus_tag="VQ878_000985"
     CDS             13110..16313
                     /locus_tag="VQ878_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET3095335.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKKLESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ878_000986"
                     /pseudo
     CDS             16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ878_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17456..18085)
                     /locus_tag="VQ878_000987"
     CDS             complement(17456..18085)
                     /locus_tag="VQ878_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET3095336.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(18095..19096)
                     /locus_tag="VQ878_000988"
     CDS             complement(18095..19096)
                     /locus_tag="VQ878_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET3095337.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19127..19768)
                     /locus_tag="VQ878_000989"
     CDS             complement(19127..19768)
                     /locus_tag="VQ878_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET3095338.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19787..20602)
                     /locus_tag="VQ878_000990"
     CDS             complement(19787..20602)
                     /locus_tag="VQ878_000990"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET3095339.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIKAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEIGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20873..21307
                     /locus_tag="VQ878_000991"
     CDS             20873..21307
                     /locus_tag="VQ878_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3095340.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21319..22509
                     /locus_tag="VQ878_000992"
     CDS             21319..22509
                     /locus_tag="VQ878_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET3095341.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEYYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22520..23011
                     /locus_tag="VQ878_000993"
     CDS             22520..23011
                     /locus_tag="VQ878_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3095342.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23026..23805
                     /locus_tag="VQ878_000994"
     CDS             23026..23805
                     /locus_tag="VQ878_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3095343.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            23792..24610
                     /locus_tag="VQ878_000995"
     CDS             23792..24610
                     /locus_tag="VQ878_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3095344.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24610..24903
                     /locus_tag="VQ878_000996"
     CDS             24610..24903
                     /locus_tag="VQ878_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3095345.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24925..26826
                     /locus_tag="VQ878_000997"
     CDS             24925..26826
                     /locus_tag="VQ878_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET3095346.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26886..27887
                     /locus_tag="VQ878_000998"
     CDS             26886..27887
                     /locus_tag="VQ878_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3095347.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27997..28332)
                     /locus_tag="VQ878_000999"
     CDS             complement(27997..28332)
                     /locus_tag="VQ878_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095348.1"
                     /translation="MKSLARLLIIHVFISIFLFFSLISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLSNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28343..28585)
                     /locus_tag="VQ878_001000"
     CDS             complement(28343..28585)
                     /locus_tag="VQ878_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095349.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28596..29138)
                     /locus_tag="VQ878_001001"
     CDS             complement(28596..29138)
                     /locus_tag="VQ878_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET3095350.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQKVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYLGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(29154..29348)
                     /locus_tag="VQ878_001002"
     CDS             complement(29154..29348)
                     /locus_tag="VQ878_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095351.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ878_001003"
     CDS             29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ878_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET3095352.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ878_001004"
     CDS             30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ878_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET3095353.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ878_001005"
     CDS             30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ878_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET3095354.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33051..34031
                     /locus_tag="VQ878_001006"
     CDS             33051..34031
                     /locus_tag="VQ878_001006"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET3095355.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10307 a         6069 c         7607 g        10141 t
ORIGIN      
        1 tcattgagta tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct
       61 tggtcgttgg taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt
      121 ttcatggcat aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca
      181 aaggcaatca aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag
      241 gccttgttga caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg
      301 atagaaagtt gatgctggta gaaggcgttc atgtcttttg ccaaggcata tttgtcactg
      361 gctctggtct gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga
      421 tcttcaggct ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga
      481 tttgtaatgt agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct
      541 gaacgttgaa ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc
      601 caaacttggt ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag
      661 cccagttcac ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc
      721 tgatggcctt tttcagcaac ttttttgatg gtttttttgg taaagtcaga aatttgactg
      781 tctgagttga gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc
      841 tttctagtgt gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca
      901 gattccaaac aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga
      961 aaaagtgaat gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga
     1021 tgatggacaa attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg
     1081 ctggtttaac aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt
     1141 cacaaacagg aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg
     1201 gtaccctgat gatggctttt tatgctaact taccttatgc ccaagcgcca ggtatgggac
     1261 tcaatgcctt ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc
     1321 tagctatggt cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta
     1381 aaatgatcat tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg
     1441 tcttccttgc ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag
     1501 gcaactatac tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact
     1561 cttcagcagt tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag
     1621 gacttgccat tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta
     1681 tcttgacaac aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt
     1741 ttgctaataa ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc
     1801 ttggttcaga aggattggga gctttggttt cagatacagc tcgcttgcct gaaactctga
     1861 tggccattct tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta
     1921 caggtgaaaa agttggtatc gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg
     1981 ataaggctct ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa
     2041 acgtaacgac ttatgttgag tctgctgctg gtatcggtgc tggtggacgt actggtttga
     2101 cagccttggt tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga
     2161 tcgtaccaac agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta
     2221 gcttgaaaaa tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta
     2281 tctttatggg attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca
     2341 ctttgactaa gcttgttaaa ggtcaagtta aagatgttca tgtcatgatt tggattttgg
     2401 atgccttgtt tatccttaac tacatcagca tggccttata atagaatgac ccagggggat
     2461 ttcccccctt ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa
     2521 ttgttgaatc gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt
     2581 cccctagtgg ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg
     2641 atagttactg gtatttctat tgtggttctg gtgctattta ttattggagc tcgtaaaacg
     2701 caattggcaa gttttaattt ttcttttttt agaactaagg atttggcacg tttgggcttg
     2761 agttatttag tcattatctg ttcaaatata cttggttcta tcttgttgca actgtcaaat
     2821 gagacgacaa cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt
     2881 tctagcttct tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg
     2941 attgttccta aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt
     3001 gtgtttgctt tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg
     3061 tcgacagttc tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt
     3121 cacatgattg ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg
     3181 acattaggaa tttctgttta aaagttttta tgtaggaacc gacctctttc tactgggaaa
     3241 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaga aataatatga
     3301 tgaaaagcct tgagggagtg accgatatgt caagtaaagc taatcatgca aagacagcta
     3361 tttgcggaat tatcaatgta accccagatt ccttttcgga tggtggtcaa ttttttgttc
     3421 ttgagcaagc gctccagcag gctcgtaaat tgatagcaga aggagccagc atgctagata
     3481 tcggcggtga atcgactcgg cctcggccgg gaagtagcta tgttgagata gaagaggaaa
     3541 tccagcgtgt tgttccagtg attaaagcga ttcgcaagga aagtgatgtc ctcatctcta
     3601 ttgatactcg gaagagtcag gtggcagagg ctgctttggc tgctggtgcc aatctagtca
     3661 atgatatcac tggtcttatg ggtgatgaga aaatggccca tgtggttgct aaggctggtg
     3721 cgaaagtagt cattatgttt aacccagtta tggctcggcc tcagcatcct agttcgctta
     3781 tcttccctca ttttggtttt ggtcaaacct ttacagaaaa agagttagct gactttgaaa
     3841 cattgccaat cgaagaaatg atggaggctt tctttgaacg agcactagcg agagcggcag
     3901 aagctggtat tgcaccagaa aatatcctgt tggatccagg aattggcttt ggtctgacca
     3961 agaaagaaaa tctgcttctt ttacgggacc tggataaact acatcagaag ggctatccaa
     4021 tctttctcgg agtgtcgcgc aagcgatttg tcatcaatat cctagaggag aatggttttg
     4081 aagtcaatcc tgagacagag cttggtttcc gaaatcggga cacggcttcg gctcatgtaa
     4141 ctagtatcgc tgcgagacag ggtgtagaag tggtgcgcgt gcatgacgta gctagtcaca
     4201 ggatggcagt tgaaattgcc tctgccattc gtctggctga tgaagcggaa aatttagatt
     4261 taaaacaata taaataagat gaaagaaatt gaaaacaatc agtggattgc taactaccgg
     4321 acggatcaac cgcattttgg cttggaacga atggtggaac tgttagcttt gcgtggcaat
     4381 ccccatctca aactcaaggt cctccatatc ggagggacta acggcaaggg ctcgactatt
     4441 gcttttttga aaaagatgct agaaaagcta gggctgagag ttggcgtgtt tagctcgccc
     4501 tatctcattc attacacaga ccagattagc atcaatgggg aatcgatctc agaagcgagg
     4561 ctagaagctc tcatggcaga ttatcagtct ttgctggagg gagaagcggt cgccaattta
     4621 cagggcacaa ccgagtttga gattatcaca gccctggcct atgactactt tgcctcagag
     4681 caagtagatg tggccatcat ggaagttggc atgggtggac ttttggatag taccaatgtc
     4741 tgtcagccca ttttgacagg aattacaact attggcttgg atcatgtggc cctacttggt
     4801 gacaccttgg aggccatagc agagcagaag gcaggtatta tcaaacaagg gatgcccttg
     4861 gtaacagggc gtattgctcc agaagccttg actgtgattg accgcattgc ggaagggaaa
     4921 gatgcgccga gacttgccta cgggacagat tatcaggttc gtcatcaaga aagtgtggtg
     4981 acaggggaag tctttgacta tacaagtgct gtcagacaag gtcgcttcca gactagcctg
     5041 cttggtttgt accaaataga gaatgctggg atggccatag ctttacttga tactttttgt
     5101 caagaagatg gtcgagagct agcaagcaat gactttcttg gtcaagcctt ggaagaaaca
     5161 agttggccag ggcgtttgga aatcgtgtca agagatccct tgatgatttt ggatggagcc
     5221 cacaatcccc atgctatcaa ggccttgttg gtaaccttgc aagaacgttt tgcagattat
     5281 cataaggaaa tcctcttcac ttgtatcaaa accaaggcct tggaggatat gttggccttg
     5341 ttgggagcca tgccagatac cgagcttact ctaacacatt ttgcggatag tcgggcgacg
     5401 gatgaaagcg tgctgaaaga ggcagctaag tctagaaatc tcagctacca agattggcat
     5461 gattttctag atcagaattt gacagataaa aaagaagaga aacaaacagt taggattgtc
     5521 acaggttcct tgtatttctt gagccaagtg agggcctatc tgatggagag gaagaacgag
     5581 aatggataca caaaagattg aagcagctgt aaaaatgatt atcgaggctg taggagagaa
     5641 cgctaatcgc gagggcttgc aggaaacacc tgctcgtgta gcccgtatgt atcaagagat
     5701 tttttcaggt cttggtcaaa cagcagagga acatttgtca aaatcctttg aaattattga
     5761 cgataatatg gtggtagaaa aggatatctt tttccatacc atgtgtgaac accacttctt
     5821 gccattttat ggtagagcgc acattgccta cattccagat ggtcgtgtgg caggcttgtc
     5881 taagctagcc cgtacggttg aagtttattc gaaaaaacca caaattcaag aacgtttgaa
     5941 tatcgaagtg gccgatgcct tgatggacta tctaggtgct aaaggagcct ttgttgtcat
     6001 tgaggcggaa catatgtgta tgagtatgcg tggtgttaga aaaccaggca ctgcaacctt
     6061 gacgacagta gctcgtggtt tatttgaaac agataaggac ctccgcgacc aagcttatcg
     6121 tttaatgggg ctataaaaag aatccgcttc aagcggattt ttctagaaag gaatcattat
     6181 ggatcaactg cagattaagg atttggaaat gtttgcctat catggtcttt ttcctagtga
     6241 gaaagaattg gggcagaaat ttgtcgtttc agccatccta tcctatgata tgaccaaggc
     6301 agctacagac ttggatttaa cagcctctgt ccattacgga gaattgtgtc agcagtggac
     6361 gacttggttt caggaaacga gtgaggattt gattgaaacg gtagcctata aactggtgga
     6421 acgtaccttt gagtcttatc ctcttgtcca agaaatgaag ttggaactga aaaaaccttg
     6481 ggcaccggtg catttgtcac tagatacttg ctcggtaacc attcatcgcc gcaagcaacg
     6541 agcctttatc gccctaggaa gcaatatggg agataagcaa gcaaacttga agcaagccat
     6601 tgacaaactg cgagctcgtg gcatccatat tctcaaagag tccagtgtct tagcgacgga
     6661 gccttggggt ggagtggagc aggatagctt tgccaatcaa gtggttgagg tggaaacctg
     6721 gctaccagca caagacttgt tagaaacctt gttagccatt gagtcagagc tgggacgggt
     6781 gagagaagtg cattggggac ctcgtttgat tgatttggac ttgctctttg tggaggacca
     6841 gatcctttat acagacgacc tcatattgcc tcatccttac atagcggaac gcctttttgt
     6901 ccttgagtcc ttacaggaaa ttgcgcctca ttttatccat ccgatattaa aacaaccgat
     6961 ccgcaacttg tatgatgctt tgaaaaaata gaaaaactct agttttcagt tacttgcaac
     7021 tgaaggctag agtttttaaa ataggtcatt ttcttctggg aggaggatag tttctctacc
     7081 gtccatgtct aaaaccagta ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc
     7141 aaaatcaatg gctgtaggga ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt
     7201 attaagcaat tgaaactcga gttcttcttc caattcaaag acatttttta agaaatgatc
     7261 gatgatatac caaaaagagt caatgatgtc atcaggcaag ctggtaacaa tgccaaaact
     7321 agcagaccgc atgtgggtat tggtaaaagc catatctctg tcccctttct tttcccttat
     7381 catacagcaa ataggattaa aaatcaagaa aaggtgattt tttgaaaagg attttaacta
     7441 cagggaaaaa gaaggaaaaa aattcccaaa aatctaccga agttaatagg taaattccca
     7501 aattaacttg attatataac tttcagttac tttgagaagt taccgaaaaa tatttttcat
     7561 atctattgac ttttaggggt gaaatttggt atgatagtag gcggtattgt ttaccccatt
     7621 tgaaaggccc cggaaccttc caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa
     7681 caaaaatcga actatatata ggagaaatca tgaacaaaac aacatttatg gctaaaccag
     7741 gccaagttga acgtaaatgg tacgtagttg acgcaactga tgtaccactt ggacgtcttt
     7801 ctgcagtagt tgctagcgta cttcgcggaa aaaacaaacc aacatttaca ccacacactg
     7861 atacaggtga cttcgtgatt gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag
     7921 caactgataa aatctactac actcactcaa accacccagg tggattgaaa caaatctctg
     7981 caggtgaact tcgttctaaa aatgcagtac gtttgattga gaaatcagtt aaaggtatgc
     8041 ttccacacaa tacacttgga cgcgctcaag gtatgaagtt gaaagtattt gttggagctg
     8101 agcacactca cgctgcacaa caaccagaag ttcttgacat ttcaggactt atctaaggaa
     8161 aggaacaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
     8221 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
     8281 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
     8341 caactgtagg ttcatacgac gttttcgtta acgttatagg tggtggatac gctggtcaat
     8401 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
     8461 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
     8521 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
     8581 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
     8641 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
     8701 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
     8761 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
     8821 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
     8881 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
     8941 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
     9001 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
     9061 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
     9121 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
     9181 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
     9241 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
     9301 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
     9361 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
     9421 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
     9481 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
     9541 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat
     9601 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
     9661 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
     9721 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
     9781 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
     9841 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
     9901 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     9961 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    10021 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    10081 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    10141 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    10201 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
    10261 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    10321 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    10381 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    10441 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    10501 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    10561 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    10621 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    10681 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    10741 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    10801 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
    10861 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    10921 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    10981 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    11041 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    11101 ttttcagggg acactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    11161 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    11221 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    11281 cgattacata gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca
    11341 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat
    11401 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    11461 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
    11521 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    11581 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
    11641 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    11701 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    11761 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    11821 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    11881 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    11941 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    12001 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    12061 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    12121 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    12181 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    12241 tattcgttat cactggtcac attgaaattg tgaaataagc acctacaaca tagactttac
    12301 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    12361 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    12421 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    12481 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgactcgttt tcctagtggg
    12541 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    12601 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    12661 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    12721 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    12781 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    12841 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    12901 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    12961 aagaataagc cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt
    13021 taactaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    13081 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    13141 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    13201 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    13261 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt
    13321 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    13381 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    13441 aattaagggc agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc
    13501 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
    13561 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    13621 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    13681 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagccc
    13741 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    13801 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    13861 cttcagtcaa aaatggaatt ttagaacctc ttaagggagg gacaaccaat gtcattgtca
    13921 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata
    13981 catacacaga ccgtttggat gactggaatg gcatcattgc tgggaatcaa tactatgatt
    14041 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    14101 tatccagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    14161 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    14221 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    14281 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    14341 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    14401 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    14461 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    14521 tgggaagagt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    14581 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    14641 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    14701 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    14761 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    14821 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    14881 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    14941 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    15001 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    15061 caggagtcgc aagtgttcca agaccaagtt acctatctgc ctttaacaag atggataaaa
    15121 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    15181 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    15241 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    15301 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    15361 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    15421 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    15481 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    15541 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    15601 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    15661 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    15721 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    15781 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    15841 atggctatat gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaaaagt
    15901 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
    15961 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    16021 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    16081 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    16141 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    16201 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    16261 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    16321 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    16381 atcttcggat ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg
    16441 tgactatagc gttttgaaac tagaatagga cgttataact actaaaagat ttctataaat
    16501 tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt
    16561 ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    16621 ataccaaaaa aactctaaac gcgatacaat aaaggtgttc aatccaattg taaagcgaaa
    16681 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    16741 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    16801 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    16861 cttaatgcca gaccatgtac acatgttagt cagtattccg tcgaggctaa gtgtttcaag
    16921 ttttatgggg tatttaaaag gcaaaagtgc actcatgatg tttgacaaac acgccaatct
    16981 caagtacaag tttgggaatc ggcatttctg ggcggaaggt tattatgtaa gtccagtagg
    17041 gcttaatgaa gccacactta agaaatatag tcaagattaa agaaattatc cagtggatga
    17101 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    17161 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    17221 gaggtgtact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    17281 atgaggatcc ctttagggat agtggtaagt aataccaaag tatcttaaag aggcaagtga
    17341 cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg
    17401 taatttgagc ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc
    17461 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    17521 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    17581 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    17641 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    17701 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    17761 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    17821 ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    17881 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgc cctgcatact
    17941 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    18001 gcagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    18061 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    18121 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    18181 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    18241 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    18301 tttttagttg gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt
    18361 tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt
    18421 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    18481 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    18541 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    18601 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    18661 cacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct
    18721 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    18781 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    18841 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    18901 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    18961 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    19021 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    19081 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttagctaata
    19141 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    19201 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    19261 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    19321 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    19381 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    19441 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    19501 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    19561 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    19621 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    19681 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    19741 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    19801 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    19861 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    19921 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    19981 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    20041 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    20101 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    20161 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    20221 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    20281 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaatctctt
    20341 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    20401 catgggcttc gatgccaact tcacgataag ctttaatccc tttattgacc agatcttgat
    20461 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    20521 caattccata agaagcgccg gtgatgaggg caatttttcc ttttaaagaa aactgctcaa
    20581 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    20641 accaaattat attctagtaa accggttttg tcaataaata aatattttta tttataaaaa
    20701 gatttatttt ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa
    20761 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
    20821 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
    20881 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
    20941 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
    21001 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
    21061 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
    21121 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
    21181 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccagg gcggagtcgt
    21241 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
    21301 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
    21361 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
    21421 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
    21481 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
    21541 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
    21601 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
    21661 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
    21721 agagaagcag ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
    21781 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
    21841 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
    21901 gatattgcag aaagccattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
    21961 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
    22021 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
    22081 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
    22141 aattatttct tgaatcgtct gccaaaagat catgtgtctt attgggattt gatttttaat
    22201 gatggtagtg atcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
    22261 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
    22321 catgccatgc ttcgttcctt gatcgaatat tatgcaaatg atcaatttac ccctggtggg
    22381 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
    22441 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
    22501 tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta tcgatgaacg
    22561 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
    22621 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
    22681 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
    22741 taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt taaccttggt
    22801 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg cccctggtaa
    22861 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc tcaaggaatt
    22921 aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
    22981 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
    23041 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
    23101 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
    23161 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
    23221 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
    23281 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
    23341 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
    23401 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
    23461 atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct ttcaatggat
    23521 accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt gacagttgct
    23581 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
    23641 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
    23701 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
    23761 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
    23821 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
    23881 ctatcaaggg ttgggatatg ccaatgtaat gtatcctgct ttgaaaaaac actatggaga
    23941 ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata ataccaatcc
    24001 acacttcctg ccttttatta ccagcttgca ccttgtaatg ttggaaaatg gccgtccggc
    24061 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
    24121 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
    24181 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
    24241 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
    24301 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
    24361 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
    24421 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
    24481 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
    24541 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
    24601 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
    24661 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
    24721 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
    24781 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
    24841 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
    24901 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagagtc
    24961 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
    25021 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
    25081 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
    25141 gatccagaat ggtcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
    25201 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
    25261 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
    25321 attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga cttgctagag
    25381 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
    25441 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
    25501 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
    25561 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
    25621 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
    25681 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
    25741 acaggcttag atggacggac tttggctttt ggtgatagcg attctacaga aacgacagaa
    25801 atgttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
    25861 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
    25921 tttgaaagga gagcttggca gcctaagtcc atgatctttg aagactctgg acatgtctgc
    25981 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
    26041 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
    26101 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
    26161 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
    26221 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgag
    26281 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
    26341 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
    26401 ttgattcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
    26461 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
    26521 gagcttgaaa gaagtagcaa gctcaccaag cgccaattct ttgagaatca gatgctggat
    26581 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
    26641 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
    26701 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
    26761 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
    26821 tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt aggaggtgtt
    26881 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
    26941 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
    27001 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
    27061 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
    27121 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
    27181 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
    27241 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
    27301 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
    27361 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
    27421 gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
    27481 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
    27541 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
    27601 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
    27661 ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
    27721 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
    27781 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
    27841 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
    27901 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
    27961 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
    28021 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
    28081 taggaatatt gaaaatttcc attggacagg gttgcttaaa agttgtggaa aggatatgag
    28141 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
    28201 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
    28261 tgaaataagg gagaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
    28321 tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
    28381 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
    28441 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
    28501 gtggaattat aaaaaatatc actgttccat aaattgaacc tgctttcaga ccaggataac
    28561 gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg atttttctta
    28621 gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa aatagaaccg
    28681 agaatgcttg atacaccatt tcttatagtg agaagagaat gaaaatagtc ctgaccttca
    28741 tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa gaacaaacct
    28801 gctttaagac ctaggtagtg tagttgcttg ctttctttct cattcagcat atctggttca
    28861 atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc gatgagggca
    28921 atcactaaaa tcagaggagg atagattaga gccacttttt gagggtattt ataggccaga
    28981 aggagtggaa taagatttcc gaaaatcatc agataaaaga ggatgataaa gacttggttc
    29041 ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat accgtatgtg
    29101 cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct tttttaaaaa
    29161 tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag attgagacag
    29221 agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg tctcgagaca
    29281 ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa ttctttcaca
    29341 cgattcatct gatctccttt ttgatttatg tcgtatatat ttgactttat tatagtcttt
    29401 taaacataaa gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc
    29461 ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa
    29521 aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac
    29581 ctgacggtat ctacgttgat gcgactttgg gcggagcagg acatagcgag tatttattaa
    29641 gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca
    29701 atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggata
    29761 acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt
    29821 gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt ttttcttata
    29881 aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag
    29941 tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac ggtgaggata
    30001 aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga
    30061 caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga
    30121 agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg
    30181 gggcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat ggtagaattt
    30241 cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc aaggaagctt
    30301 caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag cccaagatgg
    30361 aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc aataaccgct
    30421 cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga aaaagatggc
    30481 agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt
    30541 ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca ttagtattat
    30601 ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat
    30661 agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc
    30721 agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattag
    30781 aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga ccaaaaatcg
    30841 gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt
    30901 tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca ctcgctttgg
    30961 aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag ttcctgccaa
    31021 acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa cctcctataa
    31081 tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga
    31141 aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc
    31201 ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gagcaaaggg
    31261 aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag ctgcagaggt
    31321 caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc
    31381 tagttttatc ggtctagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg
    31441 aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac
    31501 ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacgaac
    31561 gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct ttatggaaac
    31621 ccagatggat gcttttcaag agaaggtaaa aggaaagtac atgacagcga ctttggtcag
    31681 tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa
    31741 agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc
    31801 aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg
    31861 aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc gagattggga
    31921 cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt ttgcacactc
    31981 aagtaacgtt gggatgactc tccttgagca aaagatggga gatgctacct ggcttgatta
    32041 tcttaatcgt tttaaatttg gagttccgac ccgtttcggt ttgacggatg agtatgctgg
    32101 tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac aagggatttc
    32161 agtgacccag acacaaatga ttcgtgcctt tacagctatt gctaatgacg gtgtcatgct
    32221 ggagcctaaa tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca
    32281 aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc ggactaacat
    32341 ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca caggcaagcc
    32401 aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc agattgctga
    32461 cgagaaaaat ggtggttatc tagtcggggt aaccgactat attttctcgg ctgtatcgat
    32521 gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac ctgaacatta
    32581 ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt cagctatgaa
    32641 agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc aacaaagtcc
    32701 ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag aattgcgtcg
    32761 caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca gttctgctga
    32821 agaagggaag aatcttgccc cgaaccagca agtccttatc ttatctgata aagcagagga
    32881 agttccagat atgtatggtt ggacaaagga gactgctgag acctttgcta agtggctcaa
    32941 tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg ttcgtgctaa
    33001 cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat atgtttattt
    33061 ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg gcctttatcc
    33121 aattttatag aaaggcgcaa attacaggcc agcagatgca tgaagatgtc aaacagcatc
    33181 aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact tctgttttgg
    33241 ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatgtggga atgattttgt
    33301 tcatattagt cttgtatggc ttggtcggat ttttagatga ctttctcaag gtctttcgta
    33361 aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta ggtggaatta
    33421 tcttctatct tttctatgag cgtgggggcg atatcctgtc tgtctttggt tatccagttc
    33481 atttgggatt tttctatatt ttcttcgctc ttttctggct agtcggtttt tcaaacgcag
    33541 taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt agtttgtctg
    33601 cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg attcttgcca
    33661 tgattggtgg tttgctcggt ttcttcatct ttaaccataa gcctgccaag gtctttatgg
    33721 gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg gctctccacc
    33781 aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact tctgttatga
    33841 tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg acgcctgtac
    33901 atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc gagtggaagg
    33961 ttgacttctt cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttgt
    34021 atttaatgta agaatggcat cctgatgttt cagggtgttt ttgtatttaa atacacaatg
    34081 aaaatcaaag aacaaactag aaagctaact ttaggctgct caaa
//
LOCUS       DAVBOM010000020        34102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBOM010000020 DAVBOM010000000
VERSION     DAVBOM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.020"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            85..366
                     /locus_tag="VQ878_001007"
     CDS             85..366
                     /locus_tag="VQ878_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET3095356.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGIDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            498..1442
                     /gene="manA"
                     /locus_tag="VQ878_001008"
     CDS             498..1442
                     /gene="manA"
                     /locus_tag="VQ878_001008"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET3095357.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1433..2937)
                     /locus_tag="VQ878_001009"
                     /pseudo
     CDS             complement(1433..2937)
                     /locus_tag="VQ878_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3042..3782
                     /locus_tag="VQ878_001010"
     CDS             3042..3782
                     /locus_tag="VQ878_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3095358.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3811..4266)
                     /locus_tag="VQ878_001011"
     CDS             complement(3811..4266)
                     /locus_tag="VQ878_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3095359.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4286..5461)
                     /locus_tag="VQ878_001012"
     CDS             complement(4286..5461)
                     /locus_tag="VQ878_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3095360.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDEVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5520..6365)
                     /locus_tag="VQ878_001013"
     CDS             complement(5520..6365)
                     /locus_tag="VQ878_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3095361.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6490..7047
                     /locus_tag="VQ878_001014"
     CDS             6490..7047
                     /locus_tag="VQ878_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3095362.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7066..7533
                     /locus_tag="VQ878_001015"
     CDS             7066..7533
                     /locus_tag="VQ878_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET3095363.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7622..8251
                     /gene="upp"
                     /locus_tag="VQ878_001016"
     CDS             7622..8251
                     /gene="upp"
                     /locus_tag="VQ878_001016"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET3095364.1"
                     /translation="MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8425..9015
                     /gene="clpP"
                     /locus_tag="VQ878_001017"
     CDS             8425..9015
                     /gene="clpP"
                     /locus_tag="VQ878_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET3095365.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN"
     gene            9094..9342
                     /locus_tag="VQ878_001018"
     CDS             9094..9342
                     /locus_tag="VQ878_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET3095366.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9443..10603
                     /locus_tag="VQ878_001019"
     CDS             9443..10603
                     /locus_tag="VQ878_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3095367.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEVAEVVKP"
     gene            10871..11740
                     /locus_tag="VQ878_001020"
     CDS             10871..11740
                     /locus_tag="VQ878_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3095368.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11744..12700
                     /locus_tag="VQ878_001021"
     CDS             11744..12700
                     /locus_tag="VQ878_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3095369.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12700..13464
                     /locus_tag="VQ878_001022"
     CDS             12700..13464
                     /locus_tag="VQ878_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095370.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13464..14174
                     /locus_tag="VQ878_001023"
     CDS             13464..14174
                     /locus_tag="VQ878_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095371.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQETTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14482..15138
                     /locus_tag="VQ878_001024"
     CDS             14482..15138
                     /locus_tag="VQ878_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3095372.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15246..16341
                     /gene="prfB"
                     /locus_tag="VQ878_001025"
     CDS             join(15246..15317,15319..16341)
                     /gene="prfB"
                     /locus_tag="VQ878_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET3095373.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ878_001026"
     CDS             16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ878_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET3095374.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17044..17970
                     /locus_tag="VQ878_001027"
     CDS             17044..17970
                     /locus_tag="VQ878_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095375.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18256..20436
                     /locus_tag="VQ878_001028"
     CDS             18256..20436
                     /locus_tag="VQ878_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3095376.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20488..21303
                     /locus_tag="VQ878_001029"
     CDS             20488..21303
                     /locus_tag="VQ878_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3095377.1"
                     /translation="MKFLTLNTYSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21443..22786
                     /locus_tag="VQ878_001030"
     CDS             21443..22786
                     /locus_tag="VQ878_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3095378.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIADSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQSMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23163..24353
                     /locus_tag="VQ878_001031"
     CDS             23163..24353
                     /locus_tag="VQ878_001031"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET3095379.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKAKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24906..25841
                     /locus_tag="VQ878_001032"
     CDS             24906..25841
                     /locus_tag="VQ878_001032"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET3095380.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25875..26912
                     /locus_tag="VQ878_001033"
     CDS             25875..26912
                     /locus_tag="VQ878_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3095381.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27085..27690
                     /locus_tag="VQ878_001034"
     CDS             27085..27690
                     /locus_tag="VQ878_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET3095382.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27846..28376
                     /locus_tag="VQ878_001035"
     CDS             27846..28376
                     /locus_tag="VQ878_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET3095383.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ878_001036"
     CDS             28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ878_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET3095384.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLLFNTMKRDRQKAVAAVNP"
     gene            29482..29964
                     /locus_tag="VQ878_001037"
     CDS             29482..29964
                     /locus_tag="VQ878_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3095385.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29966..31507
                     /locus_tag="VQ878_001038"
     CDS             29966..31507
                     /locus_tag="VQ878_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3095386.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQTKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31563..32366)
                     /locus_tag="VQ878_001039"
     CDS             complement(31563..32366)
                     /locus_tag="VQ878_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3095387.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32449..32670)
                     /locus_tag="VQ878_001040"
     CDS             complement(32449..32670)
                     /locus_tag="VQ878_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095388.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(33149..33358)
                     /locus_tag="VQ878_001041"
     CDS             complement(33149..33358)
                     /locus_tag="VQ878_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095389.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ878_001042"
     CDS             33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ878_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET3095390.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33820..34059
                     /locus_tag="VQ878_001043"
     CDS             33820..34059
                     /locus_tag="VQ878_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET3095391.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT        10381 a         6356 c         7395 g         9970 t
ORIGIN      
        1 tcttctttaa ttgatttcat attactattg tataatgatt tttgatttta gtttagtatt
       61 atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat
      121 gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc catttaccaa
      181 gatgggattg acttgcttgg ttatacgact tggagctgta tcgatccggt ttcagctggc
      241 acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat
      301 gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg
      361 gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt
      421 ataagatgta aaaaagagtt caaatggaac tctttttttg ctataatgag gggagaaaaa
      481 tcagacagga gattaagatg tcagaaccat tatttttaca atcagttatg caagaaaaaa
      541 tctggggtgg taccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaagtcg
      601 gagagtactg ggctatctca gctcatctaa atggtgtttc taaagttgcc aatggtcgtt
      661 acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc
      721 cggaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc
      781 aagttcaccc agacgatgct tatggactcg agcatgaagg cgaacttgga aaaacagaat
      841 gttggtacat cattgcagca gatgaaggtt cagagattat ctacggtcac aatgccaagt
      901 caaaagaaga actccgccag caaatcgagg ataagaactg ggatgcgctg ttgacaaaag
      961 tgccagttaa agcaggagat ttcttctatg taccaagcgg taccatgcac gctatcgggg
     1021 cgggtatctt gattcttgaa acccagcagt ctagcgatac cacttaccgt gtctatgact
     1081 ttgaccgtaa ggatgacaag ggcaatttac gtgaacttca ccttgaaaaa tctatcgatg
     1141 tcttgaacat tggtgaaccc gcaaatagcc gtccagtgac aatcaaagca gatgatctac
     1201 gttccactct ccttgtatcc aatgatttct tcgcagttta caaatgggaa attactggaa
     1261 aagttaactt tgaaaagaca gctgactaca gcttgttgag tgtcttggct ggtcaaggtc
     1321 aactaactgt tgacgggaaa aactatccaa tccaaaaagg gagacacttt atcctaccaa
     1381 gtgatgttga agcttggact ctggaagggc aagatttaga attaattgtt agtcatccat
     1441 aaaaaagaaa gggcctgagt tcattactca agtccttttg attacataaa ttgggcgatg
     1501 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     1561 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     1621 ttttaaagat atagcctgta aaaagtgaaa ggaagagagc tccaaatggc atgaggagat
     1681 tggaaaccaa gaagtccata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     1741 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt tctaaaataa
     1801 cactccattt agcacgcttg ctgttgtcct gattggtgat attgtctaca ttgatttcta
     1861 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     1921 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caggctgggt cccccttcag
     1981 actggatatt gaagggggat cgagcttgga aaatggctag acctgccatg atggatatcg
     2041 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     2101 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     2161 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     2221 ccccttccat ggcatttggc aaactgagag agcgaccgat gataaaaaca aagacgataa
     2281 agagcagggg catcatgact ttcgaagctc tttcaatctc tttttgaacc ccacgtgata
     2341 caatgaagat attcaatagg ataaaggccg cttgagctcc tagggcaatg gctggatttg
     2401 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     2461 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     2521 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     2581 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     2641 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     2701 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atggccagcc
     2761 agcagatgct agaataaaac caagtttcga cccccattgt gatttttctg acatagttaa
     2821 actctgatct cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt
     2881 ttgattgata gacttgacta tcctatcatg ttttctaagg tctgtcaaga aaatcatttt
     2941 caagttttca cacctttctc aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga
     3001 cctaagggga ggggttatac tatcattgta aggaggaaat catgtaccat ataaaagaag
     3061 ctgcgcagct ttcaggtgtc tctgtcaaga ccctgcatca ctatgacaag ataggactct
     3121 tggtcccctt aaagtcggaa aacggctatc gaacctacag tcaagaggat ttggaacgcc
     3181 ttcaggttat tctttactac aaatatctag gcttttcttt agagaaaata gcagagctgt
     3241 taaaggaaga aaggacagat ttattgcccc atttgactag gcagttggac tatctaactc
     3301 gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt caagaacaaa
     3361 aaggagaaag aaaaatgacc attgaggaaa aattcacggg atttagctat caagacaatc
     3421 aaaaatacca ccaagaagcg gtagagaaat atggtcaaga agtcatggga caagcgctcg
     3481 aacgccaaaa aggtcacgaa gacgaggcta cggccgcctt taaccaagtc tttcaaactt
     3541 tggcacaaaa tcttcaagtt ggtttacctg caacagcaac cgaaaaccag gagcaagcag
     3601 ccaagctctt gcaagccatt cgcacttatg gatttgactg ctctattgag gtattcggtc
     3661 atatcggtaa aggttacgtc tacaacccag agtttaagga aaacattgac aagtttggtt
     3721 ctgaaacagc ccagtacacg tcagatgcca ttgcggctta cgttcagaca aatgcagaat
     3781 aaataggcta ggaatttcct agcctatttt ttacttcaaa tcataaagcc agtcgtcacc
     3841 gtttttgtag taaaagaatt cactgagatc ttcttctaga aacacacgaa gcatatcaga
     3901 catatcatcg gttgcaagtt ttagatgaga aagattttca aagtcctccc accaaacttt
     3961 cccttcgtct gaagactgga gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac
     4021 ataacgataa tccttgtcgt cataccagtt tttgatacca cagagttggg gtttggaaat
     4081 gatcagacca gtttcttctt tcacttcacg aatgacagca tcgacaaagg attcgccacg
     4141 ttcaacatga ccaccaggaa aagtaatgcc agaccagtcg ggactaactc ggtcttggac
     4201 caggacctta tctccgtttt taatcataca catgttaaca aattcgactg cctctcttct
     4261 gttcattctt cacaaccttt aatctttaat cataatgcag acttcccgcc acccagccgg
     4321 tacagagggc agaagtgatg ttaaagccac ccgtgtgggc attgatatcc ataacttcgc
     4381 ctgcaaagtg gaggccaggt accagcttac tttcaagggt tttaggattg atttccttga
     4441 gactgactcc acccttggta acaaaggact ttgcaaggga catttttcca gttacaggaa
     4501 ttttaagttc tttaatggac tggacaagtt gttctcgttc cttttcagtc agttgtttga
     4561 ctttttcagg atatccttgt acaaaaaatt cggccaagcg ttctggtaac aaggttttta
     4621 aagcgttttt caaggatttt tcccgatttt cttctagaaa tgtaaccaag tccttctcag
     4681 aaagttgagg caaaacatcg agtgagagaa cctccccacc tttgacaaag ctagacatgc
     4741 gtagggcagc aggacctgac aaaccaaagt gggtaaagag taaatcatga gtgatgacat
     4801 gcttaccata acttagggtc acctcgtcca gagaaatccc ttgtaaggct ttatgtggaa
     4861 aatctgttaa taaaggactt tcagcagcct caagatcggt gatggtatgc ttaaaatggc
     4921 gagcaatctc gtgaccaaaa ccagtcgaac cagtcgaagg ataagactta ccacctgttg
     4981 tgacaatgag tttctcacaa gtgaaggttt gatccgctga cttaaggaca aactggttat
     5041 ctactttttt aacagaaacg atttctattt gagtagcaac ttgaccacct agttcggtga
     5101 ttttcttttc caaagcttcg ataatagtcc gagacttgtc actggctgga aagacgcgtc
     5161 cgtggtcttc gaccttaagt ttaacaccat tttctgtaaa aaagttgatg atgtcatgat
     5221 tatcgaactg ggagaaaaca ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca
     5281 ggttgtctaa gctaccattg ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt
     5341 tttttccaag tttccgattt ttttcgatga ggagggtttt ctgtccataa aagctactgg
     5401 aaatcgtagc catcatacca gcaggtcccc caccgatgac aatagtatca aaatgtttca
     5461 tagctctatt gtaccacaaa aaaacaagag atgatggtca cctcttgtca agaatgcaat
     5521 taatcaattt catagcccat cagcaaaccg ccctcttctg catagaaact gcagagacca
     5581 gaggttggta gaattttaat atccgcttgt gggaaggttt cacggattcg ctctgagagc
     5641 tgttgacaac atttttcgtt attgcgttgg gccatgacaa tacggccacc agcatatcca
     5701 gcttttacta actcatcata ggcagcttga actgatttct ttgatcccct tgctttttgt
     5761 agcaattcga gagttccagt ttcactagct tttccgacca tacgaatgtt gagaaggcca
     5821 acgaccgtac cgataagctt gctcaaacgg ccgttcttca ccaagttatc gactttggct
     5881 aggacaaaga gcaacttagt tttttcttga taggcagtga tagcttcaac cacttcttca
     5941 aaagacaagc cctggtcaat caagtcattc aatttttcta cgagtaggtc aacttcacca
     6001 ccagcagata aactatcaat cacatgaatc ttagtgtcag gatggtcttc cagataaata
     6061 ttctttgcta gttgagcact attgtgactg ccagaaaggg tacctgtgat ggttactagg
     6121 aaaatgtttt tggcaccttc aaatgctcgc aaatagtcat ctgggcttgg acaagctgat
     6181 tttgaagctt ctgcagttgc atacatggtt tccatcattt ggtcaatatc gagactggcg
     6241 tcatcaacaa agacctgatc agctacttga atggttaagg ggacacttac aaaggttgtg
     6301 ttaatagctg gtgttggcag ttgacgataa tcacaaccag agtcagcaat aatcttccaa
     6361 gtcatagaaa ttctccatct ttgtcagtta tacattgaca aaggttctgt ctttttttac
     6421 aattatatca tgaaaactct tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa
     6481 gaaaatgtta tgtctgaacg tagaatctct gaaaagtctc ttgaaaatct cagaaaatca
     6541 aaccaagaat ccaatttatt aaccagagaa gccattgaaa cagccctctt gcaactcttg
     6601 gaaaaaaagg agctgaccaa gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg
     6661 cgtgcggcct tttatcgcaa ttatgactcc aaagaggaaa ttttagagag cgtctttaaa
     6721 cgaactgtcc acaatattat ggaacagctg catcattacg atttaaagac agacctttat
     6781 ttggtttggg ttcacctttt ccgggaggcc agaaaggaag ctagagtaat tcaattggcc
     6841 ttggattacc atctggaaaa aatctttgtc caagccatgc aggaatttct agaaaaatac
     6901 catgggaaat caaaaggtgt cagctcttat cttcattcct tctggagctc agccatcgtc
     6961 tctgtccttc taaaatggat caaggatggc atgaaggtac cagctgaaaa gattgcagat
     7021 ttaggtttac cattttttaa aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga
     7081 ctggcctggg atgagtattt tgcagcccaa gccctactaa ttgcgaatcg ttccacttgt
     7141 aaacgtgcta aagtgggcgc gattctggta aaagataata aggtaatttc cactggttac
     7201 aatggttcgg tgtcagggac tgagcattgt attgatcacg aatgtttggt cattgaaggc
     7261 cactgtgttc gcacccttca cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt
     7321 gttcccaaag gctttacagc ctatgtaacc cattttcctt gtctcaactg tacaaaacaa
     7381 ttgcttcagg tcggctgcaa gcgcgtggtt tatatcaacc agtaccgaat ggacgactac
     7441 gcccaatacc tttatcaaga aaaagggaca gaattgaccc atttaccact tgagacagta
     7501 cagacagctc ttaaagaggc tgatctaatg taaaaattat caaaaataaa tggtttagaa
     7561 agatttttaa accgtttttt ggtataatga gaagaataaa ttgaaagaag gaattccaaa
     7621 aatgggaaaa attgaagtta ttaatcaccc actgattcaa cacaaattgt caatcttgcg
     7681 tcgtatagat acttctacaa aagcttttcg tgagctagta gatgagattg caatgttgat
     7741 ggggtatgaa gtacttcgtg atcttccact agaagatgtg gaaatcgaaa caccaattac
     7801 aaaaacagtt caaaaacaat tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc
     7861 aggtatcggg atggttgatg gtctcttgag cttggttcca gctgctaaag ttggccacat
     7921 cggtatgtac cgtgatgaag aaacacttca accagttgaa tacttggtga aattgcctga
     7981 ggacattgac caacgtcaaa tttttgtagt agacccaatg ttggcaacag gtggctcagc
     8041 aatcttggct gttgattctc ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct
     8101 tgtatctgct ccagagggtg taaaagccct tcaagaagct catccagatg tagaaatctt
     8161 tacagcagcc ttggatgaac gtttgaacga acacggttat atcgttccag gtcttggaga
     8221 tgctggagac cgcttgttcg gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt
     8281 atttccagtc acgaaaggag gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa
     8341 tttgaccttt tttgaccaag atattataat agtcttatct tcagtcattt gaccaacaaa
     8401 attaaaactc aaaaggagaa atgaatgatt cctgtagtta ttgaacaaac aagccgtgga
     8461 gaacgttctt acgatattta ctcacgtctt ctcaaagacc gcatcattat gctgacaggt
     8521 ccggttgaag acaatatggc taactctgtt attgcccaat tgcttttctt ggatgcccaa
     8581 gatagtacaa aagatattta cctttatgtc aatacaccag gtggttctgt ttcagctggt
     8641 ttggcaatcg tagataccat gaactttatc aaggcagatg tccaaaccat tgttatggga
     8701 atggctgcat ctatggggac tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg
     8761 cttccaaatg ctgaatacat gattcaccaa ccaatgggcg gtacaggtgg tggtacccaa
     8821 caaactgata tggctatcgc tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa
     8881 atcttggctg aaaattcagg tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat
     8941 aactggatga gcgcccatga aacacttgaa tatggcttta ttgatgaaat tatggccaac
     9001 aattcattga actaatgatg atagaaggca aactcgactg ggtttgcttt ttttggtata
     9061 atagggagag atttcttaga aagaggattt atcatgtttg aaaaagtcaa tcgctctggc
     9121 ttgattatct atctttacta taatcgtgat gccaaaaaac tgcaggatta tggagatatt
     9181 acctatcatt ccaagaaaca tcgttactta caactctatg ttccaactca agaagtggag
     9241 caattggtcg gacgcttgag caaggaaaaa tttattaaaa aagttagggt ttgtcatatc
     9301 caagagttgg aaacaccctt tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa
     9361 aaagttcaag gaaaacattg acaattttct gataattcgg tatattctta acagactatt
     9421 taagaaataa ggagacaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc
     9481 aagtgtagca cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg
     9541 taactcagta gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt
     9601 agctgcatac ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc
     9661 cgcaggtggt atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac
     9721 agctgaggct gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt
     9781 aggacctgcg acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt
     9841 tccattgatc tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt
     9901 tattggaact ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa
     9961 attaaatgct aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat
    10021 tgcaaaatct ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc
    10081 aggtgacaca gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat
    10141 cgttgttcct ggttactata atgaggctgg taagattgta aaccaagcgc gtggcatggg
    10201 aattgacaaa ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc
    10261 aactgctgaa aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt
    10321 ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc
    10381 aacatttgca gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc
    10441 taaaaattca ggtgaaatca aggataacct tgctaaaaca aaagattttg aaggtgtaac
    10501 tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat
    10561 gaacaatggt aaagttgaag tagcagaagt tgtaaaacca taatagaaaa atgttgaaat
    10621 agggaatgag cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt
    10681 caaactgcgt caacgtcgcc ttggattata tatgtgactg acttcgtcag tcttatctac
    10741 aacctcaaag cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt
    10801 cattgagtat aagaacctat caaaaagtga gggaaacccc tcggaattat aaatagaaag
    10861 agtgaatctt atgctccaac aactcgtaaa tggtttgatt ctaggtagtg tttacgcgct
    10921 gttagcccta ggatatacca tggtttacgg aattatcaag ctcatcaact tcgcccatgg
    10981 tgatatttat atgatgggag cctttatcgg ttatttcttg atcaattctt tccaaatgaa
    11041 tttctttgta gcgcttattg tagctatgct agcgacagct attcttggtg tcgtgattga
    11101 gtttcttgct taccgacctt tgcgccactc tactcgtatt gctgttttga ttacggctat
    11161 tggggtttct ttcctattgg agtatggaat ggtctatctg gttggtgcca atacccgtgc
    11221 cttccctcaa gcgattcaaa cagttcgata tgatttggga ccaattagct taacaaatgt
    11281 gcagttaatg attttgggca tttccttgat tttgatgatt ttgttacaag tcattgtcca
    11341 aaagactaag atggggaaag ccatgcgtgc agtatcagta gatagcgacg cggcgcaatt
    11401 gatggggatc aatgtaaacc gtacgattag ctttaccttc gctttgggtt ctgctcttgc
    11461 gggtgcggct ggtgttctga ttgctcttta ttataactct cttgagcctt tgatgggggt
    11521 tactccaggt cttaaatctt tcgttgccgc agtacttggt ggtatcggaa ttattcctgg
    11581 tgcggctctt ggtggctttg tgattggtct attggaaacc tttgcgactg cctttgggat
    11641 gtcagatttc cgtgatgcca ttgtttatgg aatcttgttg ttgatcttga ttgtccgccc
    11701 agctggtatc cttggtaaga atgtgaaaga gaaggtgtaa acgatgaagg aaaatttaaa
    11761 agttaatatt ctatggttac tccttttgtt agctggctat agcttgatta gtgtactggt
    11821 ttcagtcgga gtacttaatc tattctatgt acagatttta caacaaattg gaattaatat
    11881 tattttggct gttggtctca acttaatcgt tggtttttca ggacaatttt cacttggtca
    11941 tgctggtttc atggcgattg gtgcctatgc agcagctatt attggttcta aatcaccaac
    12001 ctacggtgcc ttctttggag ctatgcttgt aggggctttg ctttcaggag cagttgcctt
    12061 acttgtcggc attccaacct tgcgcttgaa gggggactat cttgcggtag caactctagg
    12121 tgtttctgaa attatccgta tctttatcat caatggtgga agccttacaa atggtgcggc
    12181 aggtatttta gggattccta actttacaac ttggcaaatg gtttacttct ttgtcgtgat
    12241 tacaaccatt gcaaccttga acttcttgcg tagcccaatt ggtcgttcaa ccctctctgt
    12301 tcgtgaagat gaaatcgctg ctgagtcagt tggggttaat acgactaaaa ttaaaatcat
    12361 cgcttttgtc tttggtgcca ttactgcaag tattgctggg tcacttcagg caggatttat
    12421 cgggtctgtt gtaccgaaag attacacctt catcaactca atcaacgttt tgattattgt
    12481 tgtatttggt ggactcggtt ccattacagg tgcgattgtt tcggctattg ttctgggaat
    12541 tttaaatatg cttctccaag atgttgctag tgtgcgtatg attatttacg ctttggcctt
    12601 ggtattggta atgattttca gaccaggtgg actccttgga acgtgggaac tgagcctatc
    12661 acgtttcttt aaaaaatcta agaaggagga acaaaactaa tggcattact tgaagtaaaa
    12721 cagttaacca aacattttgg tggtctaaca gctgttggag atgtgactct tgaattgaac
    12781 gaaggggaac tggttggatt aatcggtcca aacggagctg ggaaaaccac ccttttcaac
    12841 cttttgaccg gtgtttatga accaagcgag ggaacagtaa ccctagatgg tcaccttttg
    12901 aatgggaaat caccttataa gattgcctct ttgggacttg gacgtacttt ccaaaatatc
    12961 cgtctcttta aagatttaac agttttagat aatgttttga ttgcttttgg aaaccatcac
    13021 aaacagcatg tttttactag tttcttacgc ttaccagctt tttacaagag tgaaaaagaa
    13081 ttaaaggcta aagctttgga attgttgaaa atctttgatt tagatggtga tgcagagact
    13141 cttgctaaaa atctttccta cggacaacaa cgtcgtttgg aaattgttcg tgcccttgct
    13201 acggaaccta aaattctctt cttagatgaa ccagcagcag gtatgaaccc acaggaaaca
    13261 gccgaattga ctgagttaat tcgtcgtatc aaagatgaat ttaagattac aatcatgttg
    13321 attgaacacg atatgaatct ggtcatggaa gtaacagaac gtatctacgt acttgaatat
    13381 ggccgtttaa ttgctcaagg aactccagac gaaattaaga ccaataaacg cgttatcgaa
    13441 gcttatctag gaggtgaagc ctaatgtcta tgttaaaagt tgaaaatctt tctgtgcatt
    13501 acggtatgat ccaagcagtc cgtgatgtaa gctttgaagt taatgaagga gaagttgttt
    13561 cccttatcgg tgccaacggt gcaggtaaga caactattct tcgcaccttg tcaggtttgg
    13621 ttcgaccaag ttcaggaaag attgaatttt taggtcaaga aatccaaaaa atgccagctc
    13681 agaaaatcgt ggcaggtggt ctttcacaag ttccagaagg acgccacgtc tttcctggct
    13741 tgactgttat ggaaaatctt gaaatgggag ctttcttaaa gaaaaatcgt gaagaaaatc
    13801 aagcaaactt gaagaaggtt ttctcacgct ttcctcgtct tgaagaacgt aagaaccaag
    13861 atgcagctac tctttcagga ggggaacaac aaatgcttgc catgggacgc gctcttatgt
    13921 caacaccaaa acttcttctt ttagatgaac catcaatggg acttgcccca atcttcatcc
    13981 aagagatttt tgatatcatt caagatattc agaagcaaga aacaaccgtc ctcttgattg
    14041 aacaaaatgc caataaagca ctcgcaatct ctgaccgagg atatgtattg gaaacaggaa
    14101 aaatcgtcct atcagggaca ggaaaagaac tcgcttcatc agaagaagtc agaaaagcat
    14161 atctaggtgg ctaaaacaat ccagtggatt gttttagtcg gcagatgaag attacgaagt
    14221 aatcatcaat atagtccggg ggaccttttt agtcggtaga ttgagattgc aaacaaatat
    14281 gcatctacat tgaaagctta atttctaata attgaaaaaa tcgaatgaaa aatttcttac
    14341 cttcattcac agagctctat ttcagagctc tttttgctag cttattcata cttttctgaa
    14401 tttcgaaaaa gaaatgtaag cgtttgatag atttacaaaa agattgtata atagggataa
    14461 gaatagaaaa ggagaagtct catggcagtt aaagatttta tgacccgcaa ggtagtttat
    14521 attagtccag atacaacagt atctcatgca gcagatttga tgagagagca aggtttgcac
    14581 cgtctgcctg ttatcgaaaa tgatcaatta gttggtttgg tgactgaggg aaccattgca
    14641 caagcaagtc catctaaagc aacaagtctt tctatctatg agatgaatta tcttctgaat
    14701 aagacaaaag taaaagatgt catgattcgc gatgttgtca ctgtctcagg ctatgctagt
    14761 ctagaagatg caacttatct gatgttgaaa aataagatta gtattctccc tgtcgtagat
    14821 aaccatcaag tatacggagt tattactgac cgtgacgttt tccaagcctt tcttgaaatt
    14881 gcaggttatg gcgaagaagg gattcgtgta cgctttgtta cagaagatga agttggtgtt
    14941 cttggaaaaa ttgtttcttt gattgtagaa gaaaatttga atatctccca tacagtcaat
    15001 attccgcgta aggatggtaa ggtgattatc gaagtgcaaa tcgatggatc aattgattta
    15061 ccagccttga aagaaaaatt tgaagcaaat ggtattcaag tggaagaaat cgctcgcact
    15121 tcagcaaaag tcttgtaaga agggaagccc aaaggcttct tttttcatga aaaggggatt
    15181 agagcaaaag atggaaagaa atgataaaat atgctataat gaaataatgt aaaaaaggag
    15241 tatttatgga catttcagta attcgtcaga aaattgacgc aaatcgtgaa aaattagctt
    15301 ctttcagggg gtctctttga cctcgaaggg ctagaggaag agattgccat cttggaaaac
    15361 aagatgacag aacctgattt ttggaacgat aatattgcgg cccaaaaaac gtcgcaagaa
    15421 ttgaatgaat taaaaaacac ttacaatacc ttccataaga tggaagagtt gcaggatgaa
    15481 gtcgaaattt tattggattt tttggctgaa gacgagtcag tgcatgatga actggtagcg
    15541 cagttagccg aacttgataa gataatgacc agctacgaga tgactctact attgtcagaa
    15601 ccttatgacc acaacaatgc catcttggaa atccatccag gttctggtgg tactgaggcg
    15661 caggactggg gtgatatgtt gcttcgtatg tatactcgtt atggtaatgc taaaggcttt
    15721 aaagtggaag tgttggatta ccaagcaggt gatgaggctg gtattaagtc ggtaacttta
    15781 tcatttgaag ggcctaatgc ctatggtctc ctcaagtcag aaatgggtgt tcatcgctta
    15841 gtgcgaatct caccatttga ctctgccaaa cgtcgccata cctctttcac atctgtagaa
    15901 gtgatgccag aattggatga tactattgaa gtggaaatcc gtgaagatga tatcaagatg
    15961 gataccttcc gttcaggtgg tgccggtgga caaaacgtca ataaggtttc aacaggtgta
    16021 cgtttaaccc acattccaac tggaattgtt gtccaatcaa cagtggatcg tacccagtat
    16081 ggaaatagag atcgtgccat gaagatgttg caggctaagc tctatcaaat ggagcaagat
    16141 aagaaggctg cggaggtaga ttctctcaaa ggtgagaaaa aggagatcac ttggggaagc
    16201 caaatccgtt cttatgtctt cacgccttat actatggtaa aagatcaccg aactagcttt
    16261 gaggttgctc aggtagataa ggttatggat ggggacctag atggttttat cgatgcttat
    16321 ctcaagtggc gaattagcta agatagaaag gaactcacat gtcaattatt gaaatgagag
    16381 atgtcgttaa aaaatacgac aacggaacga ctgctctacg cggtgtttcg gttagcgttc
    16441 aaccggggga atttgcttac atcgtaggac cttcaggagc agggaagtca acttttattc
    16501 gttctctgta tcgtgaagta aaaatcgata aaggaagtct atcagttgct ggttttaatc
    16561 tggttaagat caaaaagaaa gatgtcccgc ttctacgtcg tagtgttggg gttgtcttcc
    16621 aagattataa attgttacca aagaaaactg tctatgaaaa tattgcttac gctatggaag
    16681 taatcgggga aaatcgccgt aatatcaaaa gacgagtgat ggaagttttg gacttggttg
    16741 gattgaagca taaggttcgt tctttcccaa atgaactctc aggtggggag cagcagcgaa
    16801 ttgcgattgc gcgtgcaatt gtaaataatc ccaaagtatt gatagctgat gagccaacag
    16861 gaaatctgga tccggataat tcatgggaaa ttatgaatct cttggaacgg attaacctac
    16921 aagggacaac tattttgatg gcgactcata atagccagat tgtaaatacc ttgcgccacc
    16981 gtgtcattgc cattgaaaat ggccgtgtcg ttcgtgacga atcaaaagga gagtatggat
    17041 acgatgatta gtagattttt tcgccattta tttgaagcct taaaaagttt gaaacgaaat
    17101 ggttggatga cagtagctgc tgtcagttca gtcatgatta ctttgacctt ggtggcaata
    17161 tttgcatctg ttattttcaa tacagcgaaa ttagctacag atattgaaaa taatgtccgt
    17221 gtagtagttt atatccgaaa ggatgtggaa gataatagtc agacaattga aaaagaaggt
    17281 caaactgtta caaataatga ctaccacaag gtatatgatt ctttgaagaa catgtctacg
    17341 gttaaaagtg ttaccttttc aagtaaagaa gaacaatatg aaaaattaac cgagataatg
    17401 ggagataact ggaaaatctt tgaaggagat gccaatcctc tctatgatgc ctatattgta
    17461 gaggcaaaca ctccaaatga tgtaaaaact atagccgaag atgctaaaaa aattgaaggt
    17521 gtctctgagg ttcaagatgg cggtgccaat acagaaagac tcttcaagtt agcttcattt
    17581 atccgtgttt ggggactagg gattgctgct ttgttaattt ttatcgcagt tttcttgatt
    17641 tcaaatacca ttcgtattac cattatttcc cgcagtcgcg aaattcaaat catgcgcttg
    17701 gttggagcta aaaacagtta tatccgtgga ccgttcttgt tagaaggagc ctttatcggt
    17761 ttattgggag ctatcgcacc atctgttttg gtctttattg tttatcaaat tgtttaccaa
    17821 tctgtcaaca aatcgttggt agggcaaaat ctatccatga ttagtccaga tttatttagt
    17881 ccgttgatga ttgccctact atttgtgatt ggggttttca ttggttcatt gggatcagga
    17941 atatccatgc gccgattctt gaagatttag gtaaaatagc tgcttttatg aggagattgt
    18001 aaaatctcct tttttgctac aagagttttt gaaaagagat gcgtagaaga aaagagcttc
    18061 caaagaagtc ccccagagaa gacttcttga tggctaattt gaacttgaaa tttggcgcac
    18121 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
    18181 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
    18241 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
    18301 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
    18361 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
    18421 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
    18481 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
    18541 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
    18601 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
    18661 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
    18721 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
    18781 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
    18841 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
    18901 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
    18961 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
    19021 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
    19081 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
    19141 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
    19201 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
    19261 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
    19321 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
    19381 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
    19441 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
    19501 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
    19561 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
    19621 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
    19681 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
    19741 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
    19801 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
    19861 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
    19921 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
    19981 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
    20041 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
    20101 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
    20161 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
    20221 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
    20281 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
    20341 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
    20401 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
    20461 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac ttacagttgg
    20521 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
    20581 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
    20641 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
    20701 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
    20761 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
    20821 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
    20881 gccctagctg aaactgtagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
    20941 tggtgggata aaggttttca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
    21001 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
    21061 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
    21121 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
    21181 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
    21241 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatatt aaactggaaa
    21301 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
    21361 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
    21421 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
    21481 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagaca agttgattcc
    21541 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
    21601 tactttcttg ttaccgattt ttcagcaatt agatgaagct agcgatagtg tacaagcagt
    21661 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
    21721 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
    21781 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
    21841 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
    21901 tgaagcagat atgaccttgg atatgggatt cttggaaact gttgataaga ttgctgacag
    21961 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
    22021 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacca aaacggttat
    22081 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
    22141 ttaccagttg actcagtcga tgcagccgta tttggcaatg atttttgtta acactaaaac
    22201 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
    22261 tggcgatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
    22321 tgagtatatt gtcgcaacag atttggcagc acgtgggatt gacattgaag gtgtcagcca
    22381 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
    22441 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
    22501 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagacgggga
    22561 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
    22621 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
    22681 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa accaagcgtg ctgaaaatcg
    22741 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
    22801 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
    22861 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
    22921 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
    22981 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
    23041 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
    23101 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
    23161 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
    23221 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
    23281 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
    23341 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
    23401 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
    23461 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
    23521 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
    23581 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
    23641 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
    23701 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
    23761 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
    23821 tcaaagaagt tattccatct tcttatcttg atgataaggc aaaattcttt atcaatccga
    23881 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
    23941 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
    24001 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
    24061 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
    24121 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
    24181 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
    24241 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
    24301 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
    24361 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
    24421 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
    24481 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
    24541 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
    24601 taatcatggg gatatttcaa gccaaagttt tattcgttat cacttgacta ttgcaaggtt
    24661 ttctagatca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
    24721 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
    24781 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
    24841 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
    24901 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
    24961 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
    25021 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
    25081 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
    25141 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
    25201 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
    25261 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
    25321 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
    25381 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gatcaagcgg
    25441 cagctatttt caacaaatat ccgctcaagt ttgtcaactg cgttaactct atcggaaacg
    25501 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
    25561 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
    25621 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
    25681 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
    25741 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
    25801 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatca aaaaatctga
    25861 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
    25921 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaaa
    25981 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
    26041 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
    26101 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
    26161 atgatgagct taagtcattt gaggaatacc ttgacaatcc ttctccaaca accaagttga
    26221 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
    26281 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
    26341 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
    26401 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
    26461 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
    26521 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
    26581 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
    26641 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
    26701 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
    26761 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
    26821 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
    26881 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
    26941 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
    27001 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
    27061 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
    27121 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
    27181 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
    27241 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
    27301 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
    27361 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
    27421 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
    27481 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
    27541 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
    27601 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
    27661 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
    27721 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
    27781 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
    27841 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
    27901 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
    27961 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
    28021 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
    28081 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    28141 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    28201 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    28261 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    28321 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    28381 agaataagga gaagaaatga aaccctcaat tcatagtttg acacatcaaa ccatgcagga
    28441 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    28501 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    28561 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    28621 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    28681 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    28741 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    28801 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    28861 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    28921 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    28981 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    29041 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    29101 tgcctttccg attgaaaaac tctttgctgc tattgaatac tacattgaga caacaaaccg
    29161 tcgtgtaacc tttgaatata tcatgcttaa tgaagtcaac gacggtgtgg aacaagcctt
    29221 ggaattggct gaattgctca agaacatcaa gaaatcgtct tatgtaaact tgattcctta
    29281 taacccagtt agtgagcatg accaatatag ccgtagtccc aaagagcgcg tgttggcttt
    29341 ctatgatacg cttaagaaaa aagggggcaa ctgtgtggtt cgtcaagagc atggtacaga
    29401 tattgacgca gcttgtggac aattgctctt taacacaatg aaacgtgacc gccagaaggc
    29461 agtcgcagcg gtaaatcctt aatgatgaag aagacttata atcatatttt ggtctgggga
    29521 gtcattttct atagcatttg cattgtctat ttttgcttta ctcctcaaga acaatctacc
    29581 gtgggagtgg gaactccaga tattcagcat cttggacgcc tggtttttct tttgactcct
    29641 ttcaattctc tctggaaact gggcgaagtg agtgacattg gacaattatg ttggattttt
    29701 ttacaaaata tcctcaatgt cttcttgttt tttcctctga ttttccaact cctttatcta
    29761 tttccaaatt tgcggaaaac aaaaaaggtc cttcttttta gttttcttgt gagtcttgga
    29821 atcgagtgta cgcaattaat cttggacttt ttctttgatt tcaatcgcgt ctttgagatt
    29881 gatgatttgt ggaccaacac tttgggtggc tatctggctt ggctccttta taaacgatta
    29941 cataaaaaca agataaggaa ttaaaatgag tattttagaa gttaaaaatc tgagtcacgg
    30001 ttttggtgac cgtgcaattt ttgaagatgt gtccttccgt ctcctcaagg gggaacatat
    30061 cggcctggtc ggtgccaatg gtgaaggaaa atcaaccttt atgagtatcg tgactggtaa
    30121 aatgctgcca gatgaaggaa aggttgagtg gtccaaatat gtgacggctg gttacttgga
    30181 tcagcactct gtccttgctg aaagacagtc ggtgcgtgat gttctccgta cggcttttga
    30241 tgagcttttc aaagctgaag ctcgtatcaa tgacctctat atggaaatgg ctgaagacgg
    30301 tgcggatgtt gatgctctca tggaagaagt aggagaactt caagaccgtc tggagagtcg
    30361 tgatttctat accttggatg ctaagattga cgaagtagcg cgtgctcttg gtgttatgga
    30421 ctttggcatg gatacggatg taacttcttt gtcaggtggg caaagaacca aggtgctttt
    30481 ggcaaaactt ctccttgaaa agcctgatat cttgctgttg gacgagccga ccaactactt
    30541 ggatgctgag catattgatt ggctcaagcg ctatctccaa aactatgaga atgcctttgt
    30601 tctcatttcg cacgatattc cattcctcaa tgacgttatc aatattgtct atcatgtgga
    30661 aaatcaacag ctgacgcgtt actctggtga ctactaccag ttccaagaag tttatgctat
    30721 gaagaaatct cagctagagg cagcctacga acgccagcag aaagagattg cagacctcaa
    30781 ggactttgtg gctcgtaata aagcccgtgt tgcaactcgt aatatggcta tgtctcgtca
    30841 aaagaaattg gataagatgg atattatcga actccaaagt gagaaaccaa aaccatcctt
    30901 tgatttcaaa ccagctcgta caccagggcg ctttatcttc caaaccaaga acttgcaaat
    30961 tggttacgac cttcctctta ctaagccttt aaatcttacc ttcgaacgca atcaaaaggt
    31021 tgcgattatt ggtgctaatg gtattggaaa aacaactctc ttgaagagtc tcttgggcat
    31081 tatctcgcca atcgctgggg aagtggagcg tggagattat ttagaacttg gttattttga
    31141 gcaggaagta gaaggcggta atcgccaaac tcctcttgaa gctgtctgga atgcctttcc
    31201 tgcccttaat caagcagaag tccgtgcagc ccttgcccgt tgtggtttga caaccaaaca
    31261 tattgaaagc cagattcaag tattatcagg gggagagcaa gccaaggttc gtttctgtct
    31321 cttgatgaat cgtgaaaaca acgttttagt gctggacgag ccgaccaacc atttggatgt
    31381 ggatgcaaag gatgagctca aacgcgctct caaagaatat aggggatcta tccttatggt
    31441 ctgccacgag ccagactttt atgaaggctg gatagaccaa atatgggatt ttaataattt
    31501 aacttaagaa tgagagtaaa agaaatacag taccgaatgt ggatactgta tttttttggt
    31561 ttttaagatt taaaatcgta gtctttcacc acttcgatgc tgtcgattgt gatagcagta
    31621 gttggcttgt ctttttcatc tttttcggcc ttagcaatct tatccacaac atccataccg
    31681 tcaatcactt gaccaaagac tgggtgtttg ccatctagac tagggtttcc accttctttg
    31741 taggcttcga taattttctg tggatacttg cttgtaggga gtttagaaga ggtatctgta
    31801 gagctttggt tgatgaagaa ctggctgcca ttggtgtttg gttgaccagt attagccata
    31861 gcaagagcac cacggatgtt atacaaataa ggagtaatct cgttcttgaa accagttcct
    31921 ttgtctttag tcttatcctt gtcatgccag atggactgac cacctgtacc gtcccctttt
    31981 ggatctccag tttggaccat aaagccatcg atgacacggt ggaaggtaat accgttatag
    32041 tagccttctt tggcgtgagt gaggaaattt tcaaccgcta gaggagcgag tttagggaag
    32101 agtttaatgc gaatatcacc ttggcttgtg tggagaatca cttcggcttc atcttcagca
    32161 acttccttag atagttgtgg gaaattggcg ttttcgtttg ttaaagcatc gtttaactcc
    32221 ttggcagatt gggcagctac tttggaactt tcttcagcag caagactgga atcaacataa
    32281 tcatcaccac gcagactgcg ttggacgctg ctacacccag ctagggctac agtagacagt
    32341 aaaagaaggg ttgctagttt tttcattctg atcctctcaa aaattcattt ataccattgt
    32401 accctaaaaa gaagtggatt tcaaatatta gtagtttaca gaactggctt agataatagt
    32461 tgggatttca tcatcatctt gaaaatcttc aacttcttca acttcttccc cagtaaatgg
    32521 tttctgaaaa gaacttagta taaaacgggc aattggttca acaattagga aatttagagg
    32581 aagagctgca ataaagttta cgaaccaggc gcttagatag gtattgggtg tgatagcaat
    32641 gccattgtaa aaaagtccat agaaggacat gaaagtgacc agctaattct tcttctgaaa
    32701 aatgctcatg aagggcttga tccaggtcgc aagatttcat tttagaaagt ccagtaactc
    32761 ccttcttctt caggatattc tttttcatgg tattatttag atggtcaagt gagtcaaaag
    32821 aagtttcgac aagagcatac cctttttcta tcagagtttt tagatgttta ggggcatcaa
    32881 taccataagt gtactcaaag tattttggaa accagatctt aagaaagctc gtaaagctag
    32941 ccagttctct aaacgctaag aactagctac aacacagcat ttacaacact tcatggttca
    33001 caccatgggg tgctttttaa tgattttaag caaaattcac acttaattga aagttattta
    33061 aattagatga aaatttattt tttgaaaaag cgggaaaaca ttgattctaa gcgaattttg
    33121 aatcatattc gaatgggagt ttttaaaatc atgtttcagt ggtaaaagta ccaaactgga
    33181 ttctccatag taaaatgata tctcctgcta gtgaatcatc tactaataag tccatatttc
    33241 gcttgggaac gggcttggga cttagaagcc aagtatccaa ctctcgttca ggcgatatga
    33301 agggtttgac ttggtgttct ttataaaatt tttctaaaat agtattcacg gatagcatct
    33361 ttcaaacatt tatttcctat tctaacaaat ttctaaatac tttaagaaat ttatagtctg
    33421 tcaagttttt ttcttgacac atgccagaaa tctgctataa tagaacatgt gctaaatagc
    33481 tcagctattt caccgaaata aaaaattaaa gaaatgagac tttaaaaatg gcagttaaaa
    33541 tccgtttgac tcgtatgggt tctaagaaaa aacctttcta ccgtatcaac gtagcagatt
    33601 cacgttcacc acgtgacgga cgtttcatcg aaacagttgg aacttacaac ccacttgttg
    33661 ctgaaaacca agtaactttg aaagaagacc gcgttcttgc atggttggct aatggagctc
    33721 aaccttcaga cacagtacgt aacatccttt caaaagaagg cgtattgaaa aaattccacg
    33781 attctaaatt ctcaaaataa gtttaaagta ggttgacaga tggatacgat tgaaaatctc
    33841 attattgcga ttgtgaaacc cttaatttca caaccagatg ccttaactat caagattgag
    33901 gatacaccag aatttttgga atatcatttg aatcttgatc aaagcgatgt gggtcgtgta
    33961 atcggtcgta agggtcgcac tatttctgcg ataagaacga ttgtctactc tgtcccaact
    34021 gaatacaaaa aagtaagaat cgttattgac gaaaaataag aagggcggga cggatgtctc
    34081 gcttttttgt gtggaataga ag
//
LOCUS       DAVBOM010000021        32930 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBOM010000021 DAVBOM010000000
VERSION     DAVBOM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32930
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.021"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(287..574)
                     /locus_tag="VQ878_001044"
     CDS             complement(287..574)
                     /locus_tag="VQ878_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095392.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(584..994)
                     /locus_tag="VQ878_001045"
     CDS             complement(584..994)
                     /locus_tag="VQ878_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3095393.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            1062..1793
                     /locus_tag="VQ878_001046"
     CDS             1062..1793
                     /locus_tag="VQ878_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095394.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1790..2839
                     /locus_tag="VQ878_001047"
     CDS             1790..2839
                     /locus_tag="VQ878_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095395.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPMDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(3007..3336)
                     /locus_tag="VQ878_001048"
     CDS             complement(3007..3336)
                     /locus_tag="VQ878_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET3095396.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            3613..3951
                     /locus_tag="VQ878_001049"
     CDS             3613..3951
                     /locus_tag="VQ878_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3095397.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            3956..4693
                     /locus_tag="VQ878_001050"
     CDS             3956..4693
                     /locus_tag="VQ878_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3095398.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            4707..6047
                     /locus_tag="VQ878_001051"
     CDS             4707..6047
                     /locus_tag="VQ878_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3095399.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6091..6246)
                     /gene="blpC"
                     /locus_tag="VQ878_001052"
     CDS             complement(6091..6246)
                     /gene="blpC"
                     /locus_tag="VQ878_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET3095400.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(6303..7664)
                     /locus_tag="VQ878_001053"
     CDS             complement(6303..7664)
                     /locus_tag="VQ878_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET3095401.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASIKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(7675..9828)
                     /gene="blpA"
                     /locus_tag="VQ878_001054"
     CDS             complement(7675..9828)
                     /gene="blpA"
                     /locus_tag="VQ878_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET3095402.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLNQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            10110..10364
                     /gene="blpM"
                     /locus_tag="VQ878_001055"
     CDS             10110..10364
                     /gene="blpM"
                     /locus_tag="VQ878_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET3095403.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            10380..10583
                     /gene="blpN"
                     /locus_tag="VQ878_001056"
     CDS             10380..10583
                     /gene="blpN"
                     /locus_tag="VQ878_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET3095404.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            10827..10976
                     /gene="blpO"
                     /locus_tag="VQ878_001057"
     CDS             10827..10976
                     /gene="blpO"
                     /locus_tag="VQ878_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET3095405.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            11080..11199
                     /locus_tag="VQ878_001058"
     CDS             11080..11199
                     /locus_tag="VQ878_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET3095406.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            11667..12038
                     /locus_tag="VQ878_001059"
     CDS             11667..12038
                     /locus_tag="VQ878_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095407.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            12667..13050
                     /locus_tag="VQ878_001060"
     CDS             12667..13050
                     /locus_tag="VQ878_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET3095408.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            13102..13791
                     /locus_tag="VQ878_001061"
     CDS             13102..13791
                     /locus_tag="VQ878_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3095409.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            13833..14066
                     /locus_tag="VQ878_001062"
     CDS             13833..14066
                     /locus_tag="VQ878_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095410.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            14217..14828
                     /locus_tag="VQ878_001063"
     CDS             14217..14828
                     /locus_tag="VQ878_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3095411.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            14989..15783
                     /locus_tag="VQ878_001064"
     CDS             14989..15783
                     /locus_tag="VQ878_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET3095412.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            15780..16415
                     /gene="trmB"
                     /locus_tag="VQ878_001065"
     CDS             15780..16415
                     /gene="trmB"
                     /locus_tag="VQ878_001065"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET3095413.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            16541..17020
                     /gene="rimP"
                     /locus_tag="VQ878_001066"
     CDS             16541..17020
                     /gene="rimP"
                     /locus_tag="VQ878_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET3095414.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            17064..18200
                     /gene="nusA"
                     /locus_tag="VQ878_001067"
     CDS             17064..18200
                     /gene="nusA"
                     /locus_tag="VQ878_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET3095415.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            18222..18515
                     /locus_tag="VQ878_001068"
     CDS             18222..18515
                     /locus_tag="VQ878_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET3095416.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            18508..18807
                     /locus_tag="VQ878_001069"
     CDS             18508..18807
                     /locus_tag="VQ878_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET3095417.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            18824..21616
                     /gene="infB"
                     /locus_tag="VQ878_001070"
     CDS             18824..21616
                     /gene="infB"
                     /locus_tag="VQ878_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET3095418.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            21867..22217
                     /gene="rbfA"
                     /locus_tag="VQ878_001071"
     CDS             21867..22217
                     /gene="rbfA"
                     /locus_tag="VQ878_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET3095419.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            22496..23275
                     /locus_tag="VQ878_001072"
     CDS             22496..23275
                     /locus_tag="VQ878_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095420.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            23277..23459
                     /locus_tag="VQ878_001073"
     CDS             23277..23459
                     /locus_tag="VQ878_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095421.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            23456..23596
                     /locus_tag="VQ878_001074"
     CDS             23456..23596
                     /locus_tag="VQ878_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095422.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            23909..24142
                     /locus_tag="VQ878_001075"
     CDS             23909..24142
                     /locus_tag="VQ878_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET3095423.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            24142..25476
                     /locus_tag="VQ878_001076"
     CDS             24142..25476
                     /locus_tag="VQ878_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET3095424.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            25486..25740
                     /locus_tag="VQ878_001077"
     CDS             25486..25740
                     /locus_tag="VQ878_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET3095425.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            25836..26231
                     /locus_tag="VQ878_001078"
     CDS             25836..26231
                     /locus_tag="VQ878_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3095426.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQTAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            26644..27093
                     /locus_tag="VQ878_001079"
     CDS             26644..27093
                     /locus_tag="VQ878_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET3095427.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            27080..27640
                     /locus_tag="VQ878_001080"
     CDS             27080..27640
                     /locus_tag="VQ878_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095428.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            27640..28218
                     /locus_tag="VQ878_001081"
     CDS             27640..28218
                     /locus_tag="VQ878_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3095429.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            28211..30862
                     /locus_tag="VQ878_001082"
     CDS             28211..30862
                     /locus_tag="VQ878_001082"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET3095430.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            30932..31687
                     /locus_tag="VQ878_001083"
     CDS             30932..31687
                     /locus_tag="VQ878_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET3095431.1"
                     /translation="MSKHPHYELLNLIGYGLAKFAKLFIKEFQYSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKM
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            31962..32765
                     /locus_tag="VQ878_001084"
     CDS             31962..32765
                     /locus_tag="VQ878_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET3095432.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
BASE COUNT         9770 a         5842 c         7252 g        10066 t
ORIGIN      
        1 tgttttgagc tgacttcgtc agttctatcc acaaccttaa aacggtgttt tgagcagtct
       61 gtgcctagct ttctagtttg ctttttgatt tttattgagt atgagttacc taaattatga
      121 tgcatagttg atgggatata tataatagat tgaaatagaa tatgaacaaa ttgataagag
      181 gattttaaag taatctctaa caatgcttta gaaactatag tgtgctattc taaattcaat
      241 tcactataac ttgtttacgt tttaaaaaag agccgggggg ctctttttac ttatcttcag
      301 ttccctgcat ttcttttatc acagctagtc tagtctggat atccttttcc aagaccttaa
      361 acttgtaagt caagtcttct tggtattcct tgataagttc tttttgctgg ttaatgattt
      421 gcaggctgtt ttggataata tccacatcgt ccttgatagc ttgaacgcgg tcagtggtat
      481 tcaagacttc atctgtgatg gtttggcgat tttttgtaac cagataactt ccggctgcag
      541 ctcctgcaaa tagcagtagg ttggataatt tcatagcaac tccttaagcg tttttgatgg
      601 tttcagcgac ttgagcaagt ttgtcaaagt ctggttcgtg ggcgataaaa tcaatcttga
      661 ggtcatcgtc agcactgtag cgaggcacaa ggtgaacgtg agtatgaaaa actgtttgac
      721 cagcgacttc ttcacagttg gaaatgatat tcataccagc agccttagtg actttcatga
      781 ctttttgagc tacttttggt acttgggcaa agagttggct ggcgctcgta gcatccatct
      841 ccaaaagatt gcgatagtgt tcttttggca cgaccaaggt gtgtcctagt gttacttgag
      901 agatatcaag aaaggcaagg acctgctcat cttcatatac ttttgaagca ggaatttccc
      961 ctgcgatgat tttacaaaaa atgcaatctg acataaaatc tacctctact gtactgaatt
     1021 ttgatataat atagctacat tataccagat ttggagaaaa tatgttagaa attaaaaacc
     1081 tgacaggtgg ctatgttcat gttcctgttt tgaaagatgt gtcctttact gttgaaagtg
     1141 ggcagttggt cggtttgatt ggtctcaatg gtgctgggaa atcaacgacg atcaatgaga
     1201 ttatcggtct gttggcacct tatagtggct ccatcaatat caatggcctg actctgcaag
     1261 gagatgcgac tagctaccgc aagcagattg gctacattcc tgagacgcct agtctgtatg
     1321 aggaattgac cctcagagag catatcgaaa cggttgctat ggcttacggt attgagcaaa
     1381 aagtggcttt cgaacgagta gagcccttgt taaaaatgtt ccgtttggaa cagaaattag
     1441 actggttccc tgttcatttt tcaaaaggga tgaagcagaa ggtcatgatt atctgtgctt
     1501 ttgtggtgga tccaagtctt ttcatcgtgg atgagccttt ccttggtctt gatccgctgg
     1561 ctatttctga tttgattcag cttttggaag tggagaagca aaagggcaag tctattctca
     1621 tgagtaccca cgtgctggat tcggcggaga agatgtgtga tgcctttgtc attcttcaca
     1681 agggagaggt gcgtgccaaa ggcaatctcc tgcaactacg tgaagccttt gatatgcctg
     1741 aggctagttt gaatgatatt tacttggctc tgaccaaaga ggaggatcta tgaaagactt
     1801 gtttttaaag agaaagcagg cctttcgtaa ggagtgtctt ggttatctgc gctatgtgct
     1861 caatgaccac tttgtcttgt tcctgcttgt cctgttgggc tttctagcct accagtacag
     1921 tcaactctta caacattttc ctgaaaatca ttggcctatc cttttgtttg taggaattac
     1981 gtctgtttta cttttacttt ggggaggaat tgccacctat atggaggctc cagacaagct
     2041 ctttctctta gttggagaag aggaaatcaa gctccatctc aagcgtcaaa ctggcatttc
     2101 cctagtcttt tggctctttg tacagaccct tttcttgctg ttatttgcgc ccttgttttt
     2161 agcaatgggt tatggcttgc cagtttttct gctctatgtg cttttattgg gggtaggaaa
     2221 atatttccac tttcgtcaaa aggccagcaa atttttcact gaaactggac tggactggga
     2281 ctatcttatt tctcaagaaa gcaagcgtaa gcaagtcttg cttcgtttct ttgccctctt
     2341 tacgcaggtc aagggaattt caaacagtgt caagcgtcgt gcctatctgg actttatctt
     2401 aaaggctgtt cagaaggtgc ctgggaagat ttggcaaaat ctctatctgc gttcttatct
     2461 gcgaaatggc gacctctttg ctctcagtct tcgtcttctc ttactttccg tactggcgca
     2521 ggtttttatc gagcaagctt ggattgcgac agcagtggta gttctcttta actacctctt
     2581 gctcttccag ttgctggccc tctatcatgc ctttgactac cagtatttga cccaactctt
     2641 tccgatggac aaggggcaaa aggaaaaagg cttacaggag gtagttcgag gattgaccag
     2701 ttttgtttta cttgtggaag tagttgttgg gttgattacc ttccaagaaa aactagccct
     2761 tctagcctta ctaggagctg gtttggtttt actagtcttg tatttgcctt atcaggtaaa
     2821 acgtcagatg caggactaac attgctgata cgacactaaa aaagaagttg agttcagtct
     2881 gtctcaactt cttttttgtt actacaggat aatggttggt ccgtagagac ttatactctt
     2941 cgaaaatctc ttcaaaccac gtcagcgtcg tcttaccgta ctcaagtaca gcttgcggct
     3001 agcttcctag tttgctcttt gattctcatt gagtattaac ttggtcttga cttggtcaaa
     3061 gtggaagcgg tcataggccc gccaagcggc gcgagttgga gcatctggat caagagcgct
     3121 gagtcccatg agaagactgg aagtctggta aaatttttcc aattcaatca agaatcgatt
     3181 atccactgtt tcagccttgg ctagaaaacc aagaatagag tttaattgct cctgaaagcg
     3241 gacgtcgtca gcggttgcct gtttgcatgc ttgataggct ttgtttaagt cagtaatcaa
     3301 agtctgagct cttttgatag ggtctgtatc tgtcatgaga attcctcctc taatctgggt
     3361 gccagtcttg attctagcaa ctgtgttttg atactgtcag tctatcactt ttatctcctt
     3421 tttcgccttt aaatctttaa ttgtcattga aatgtcttga attgcgctga gtgaatttta
     3481 tgataaaata gtggtaagct catcatgata ttgtagaaaa ataattcttt taggagcttt
     3541 caaagactgt ttaggattgg gtgtgcttgt gttagatttt ttctgttatt cttttcttag
     3601 gaggagaatc caatgaaaca tatgattatt cagacacaga aaacagtcta taaagtaaac
     3661 gtcgacgatg tctactatat ccaaacacat ccaactaaag cccatactgt aaagattgtt
     3721 acagaagagg ctagttttaa tatggttcaa aatttaagta atcttgagaa ccaatatggg
     3781 gaaaccttga tgagatgtca tcgaaattgt ttggtcaatc ttgataaagt aaaatcgatt
     3841 gattttcaag aaagaatcct ttttcttgga gaagaaggtc aatacgctgt caagtatgcc
     3901 agacgtcgct atagagaaat tcgtcaaaaa tggttgaaag aaggagagta agaagatgag
     3961 aatatttgtt ttagaagatg atttttccca acagactaga attgaaacga cgattgagaa
     4021 actcttgaag gaacatcata tcactctgag ttcttttgaa gtttttggta agccagatca
     4081 attgctggca gaggtgcatg agaagggggc ccatcagcta ttctttttgg atattgagat
     4141 tcgaaatgag gagatgaagg gtctggaagt ggctagaaag attcgggatc gggatccgta
     4201 tgccctgatt gtctttgtga cgactcactc ggagtttatg cccctgtcct ttcgctacca
     4261 agtgtctgct ctggattata ttgataaggc cctttcggca gaggagtttg aatctcgtat
     4321 cgagacagcc ctcctctatg ccaatggtca agacagtaaa agtctagcgg aagattgctt
     4381 ttactttaaa tcaaaatttg ctcaattcca gtatcctttt aaagaggttt actatctcga
     4441 aacgtccaca agaccccatc gtgttattct ctataccaag acagacaggc tggaatttac
     4501 agcgagtcta gaggaggttc tcaagcagga gcctcgtctc ttgcagtgcc atcgctcttt
     4561 tctcatcaat cctgccaatg tggtgcattt agataagaaa gaaaaactgc ttttctttcc
     4621 caatggtgga agttgtctaa tcgcgcgtta taaggtcagg gaagtgtctg aggctattaa
     4681 taacttacac tgagctagga gagtttatga atgttgcttg gatattgttg tatacacttg
     4741 ttactcacgg attaaaaatt gtcatattct ttaaggtaga tggaattagt ctcacttttg
     4801 agaggatttt taaggccttt ctttttaaga tactgttggc cgttgttttt ggaatgcttg
     4861 gctatatggt aggaaatgtt tacctatctt attttatgga acccttgtac ggcataggct
     4921 tatctttctt attgttaaga gaacttccta aaaaactcct tctcttttat ggtctctttc
     4981 caatgatatt agtgaatctc ttttatagag gtgtttccta ttttgtgctt ccatttttgg
     5041 gacaagggca agtatatgat gactactcat ttatttggtt atgtataata attttcaatt
     5101 tcttcatttc tctagctttt ttgaaatggt tggactatga tttcactagc ttgagaaagg
     5161 ggattctcga taaagatttt caaaagtccc tgactcagat taactggata atgggggctt
     5221 actatttggt gatacaaaat ctgtcttact ttgaatatga acaggggatt caatcaacga
     5281 ctgttcgcca tctcatccta gtcttttacc tgctcttttt tatggggatt atcaagaaat
     5341 tggataccta tttgaaggac aaactccatg agagactgaa ccaagagcag gacttgcgct
     5401 acagagagat ggagcggtat agtcggcata tagaggagct ttataaggaa gtacggagtt
     5461 ttcgccatga ctacaccaac ctcttgacta gcttacgtct gggcattgaa gaggaggata
     5521 tggagcagat aaaagagatc tacgactcgg tcttaaagga ttctagtgaa aaattgcagg
     5581 acaataaata tgaccttggc cgattggtga atgttcggga tcgtgccctc aaaagtctcc
     5641 tagctggaaa atttataaaa gctagagata agaacattgt ctttaatgtc gaagttccag
     5701 aggagattca ggtagagggg gtgagtctac ttgattttct aaccgttgtg tctatccttt
     5761 gtgacaacgc tattgaagct agtgtagaag cctgtcaacc tcatgtttca attgcctttt
     5821 ttaaaaatgg agcacaggag acctttatca ttgaaaattc catcaaagaa gagggaatcg
     5881 atatttctga aatcttctcc tttggagcaa gttctaaagg ggaggagaga ggagttggtc
     5941 tctataccgt tatgaaaatt gtggaaagtc atcccaatac cagtctcaat accacctgcc
     6001 aagatcacgt ttttcgtcag gtacttactg taatacatat agaatgaaga aaaaataaga
     6061 ccgagagtgc gttctcttgg tcttgttttt ttatagttgt attggctgat aaaatccttt
     6121 tgtatttttt tgttcaatta tattaaatct atataagaaa tcttcccacc atcctccacc
     6181 tataatttgg ttgagttcgg tagttgttag ttcttgaaat gaagttaggt tttgtttctt
     6241 atccatgtta tgattctcct ttttgataag ataataaata gttatagagt gttatctgaa
     6301 aattaatcag aatgggttaa aattttatct ttgaaataat caaaatatgt tttctttgta
     6361 gttacactag tgacgcgacc ttgtaagcca tattggatga gtttactatc ctcgttagat
     6421 agttttgcaa gagcggttaa tttaaagaga ttgccttgct ctgttctggt aggagtttga
     6481 tcaatactct gaagttggcc gatgatggtg gtgccgtgat ttccaatctt ctccagtttt
     6541 aatcttacag tttgtccttt atctagtaag gggagatagt cagatgatac gtagtaagtg
     6601 attagtactt ctcttgtatc tgtgatgaca gggaatattt gagcaatttc tgtaccagtt
     6661 ggaattctat ttttaccttc aaattcgctg ttcagatgaa cgataccttt acttggagcg
     6721 gttaaggtat tattttctaa gcgctgtgtc gcttgatcta gttgtacttt taattctgtt
     6781 aattgattct ccacggttag ttgttgctgt gaggctgttt gtaaaaactg agtgcggagt
     6841 acttcaattt tggttgctaa actattatca taagttgcta cacttccgat accagcttgc
     6901 tgaattttga tgcttgcgat agatgattca agacttgcaa tactttgatt aatttgagat
     6961 aaaaatggct cctctgccgt tccttgtgtt tgtccttgag aggctataag ataacgattt
     7021 aaaattgact ggtgcggatt gccagttggt aagcgtgctc tgttatttat gatagcatct
     7081 ctcaactctt gatattctcc aatttgttgt tgaacttttg taatttcttg ttcgatggct
     7141 gatgaactgc tattggtaag attagcttga tttgaaactt cagtgttagt ctttgagata
     7201 cccagttcaa tatcatggga ttgtttagta aaattcataa aggtattatg gtagccaaac
     7261 tcatcctcgc tagaaaaaag atcagtcgct ttttctaagc tttgtttcaa gattccaagt
     7321 ccttcttttt gcttctcaag tctttgtaat tgagttgcta aggcagtttt ctgactttct
     7381 tccattgttt cagagtattt gatgagtaag tcacctttct caactacttg atttgccact
     7441 aaatgattag caaggatagg attatcactg gtcgactgaa tagatgcaat gacacttgta
     7501 ggggcgattt ctccttggga agtaacagta atttcttttg tggcaacaag ggagaaaatc
     7561 aagatgaaag taaatagtaa tgaaagaggt ataatgaaca ctgtcgcata gttatggtaa
     7621 cgtctctgat aaaactcgac acttctaaaa agattaggat tcatgacatt ctccttattt
     7681 attgaataga tgatggtaga agccttgcgc ctgcattaac tcttggtgac taccaacttc
     7741 aatgattttc ccctggttaa gaacaatgac acggttagtt cgttcggcta tactgagacg
     7801 atgggctaca aagagaatgg ttttatcagt tagggatata agattatcta taaccttttt
     7861 ctcagtcaag acatcaagac cgctagtagc ttcatctagt attaaaacag gagctttagt
     7921 taaaagagca cgagcgagag cgattcgttg cttttgtcct cctgatagac cagctccatc
     7981 agagagctga gtttgatagc ccataggcat tctttcaatg tcttgacgga tttcagctaa
     8041 ttcacaagct cttagaatat cttcttggct aatcatatga ttaccgccca aggttaaatt
     8101 ttccaagata gagccattaa agatataggc ttgttggggt aggtaattaa tatgacggcg
     8161 caagactttt ttatcaatgt ttttaatatc ctgataattg atggaaatat gccctttgta
     8221 gggttcaaag aaattgacaa tcattttggc taaagttgtt ttaccagaac cactaactcc
     8281 aactaggcta accttatctc cttgtttaat cgtgagatta atatctgtta aggtatctcg
     8341 tccaaaacca tacttataag aaaggtcatc aaattcaata tcgcccatca aaaaatgtga
     8401 atgaacaggg ttttcttgaa cttgaaattc agattcgact agatagactt cgttcaaacg
     8461 gttattagcg accttcgcag attggagttt ggtttggagg ttgataatat tttccatagg
     8521 agttgtaaag taagaaaaaa gtgtgttaaa ggtaatcagc tgaccgatag aaattttact
     8581 cgacatgact aattgagcgc caaaccatag gataaggata ttcagaacta attttgttcc
     8641 ctgctttaaa ctcgtttgta aaatagaata tttactgagc ttaaaggatt tttccaaata
     8701 atctacaaat tcgctgtcta tattttgata gcgattttct tcactcgtga gcgactttat
     8761 agtttcaatc ccgttgatat cttcgataat ggcagagcta accatagaat tactttgcat
     8821 gacatcatgg ttcatttttt cgaaaggttt cataaaagaa aagatgatga acatgtatat
     8881 aggaatggaa agaagagaaa ggaggaagag attagggttt tgtgccagta agacgccccc
     8941 tacaagaatc agaatagaaa catccagaaa aagagaaaga atggtagaag ccaaggcatc
     9001 tataatagag ttagcatctg tgaaccgtga aatgatttct cctgtacgac gtgtcgcaaa
     9061 gaaagacatg ggaagttcaa aaatatggcg aatataggat aaaatcacat caatgcttaa
     9121 tctctggctc agaacggtta ggagataatc tctggaaaag ctcatgactt gttggaggat
     9181 ataggtgata accagaccaa ctgagatgat tcctaaagtt gatttcatct gatttgggat
     9241 gtattcatcc aagattcctt ggagataata agaaccaccg atattgataa tagtgaccaa
     9301 taagcttgag agaacaatgt aagcaatgag agatttttgt ttgaaaatca gaggaaggaa
     9361 gcttagtaga ccattctttt tatctttatg gggttgatag ctgggtttgg gagctagaaa
     9421 aatagctact ccagtccatt cagagaaaaa gcgttctttt gacattttag tgatttttac
     9481 agaagggtca ggatcaccaa taatcagata gtctttcttt gtttgataga caacatagta
     9541 atgttggagt tttccttctt tgttaacgtg aacgataaat ggatagggga catcactcat
     9601 gtcaaagaga gttttatctg cttgaacagg ccttgtttca aagcccattt catcagcggc
     9661 ttttacaatg ccaagagcag tcgtcccttc tttattggtc tttgcaagtt ctctcaagtg
     9721 agctagagaa aaatctgaac catagaattt agcaatcgag gctaaggcag caacaccgca
     9781 gtctctagca tctatttgag gaacaaatgt acgtttataa gaagtcattg gcaattcctt
     9841 tcatatagtg gatagctcta ttatgacata aaaacaattt cgtgctttat aaaatcttga
     9901 atagtcattg aaatttcctg aatggtaaaa aagtgattag aaattatctt ttaaaaaaaa
     9961 tttagaggta gttttaaata aaaaagctaa tttaagacgt ttcgatgaca attcaagatt
    10021 tggatgaaaa actttaacaa atagtgctat actaaacttg tcaaagttgc aacaagacaa
    10081 aaattaaaaa taaaaaagga gtatttgtta tgaatacaaa aatgatggaa caatttcatg
    10141 aaatggatat agctatgtta tctagtattg aaggaggcaa gaataattgg caaactaatg
    10201 ttttcgaagg tggtagtgct gcttttggtg gctgggggtt agggacagct atttgtgctg
    10261 cgagtggtgt tggagcgcca tttatgggag catgtggata cataggagct aaatttggtg
    10321 tggctctttg ggcaggagta acaggggcaa cgggtggatt ttaacaaaag gagacttgta
    10381 tgaatactta ttgtaatata aatgaaacaa tgctgagtga ggtttacgga ggtaattccg
    10441 gaggagcagc tgtagttgct gctttaggtt gtgcagcggg tggagtgaaa tatgggaaaa
    10501 ttctaggacc atggggcgct gcaataggag gaattggagg agcagtggtt tgtggatatt
    10561 tagcctatac cgctacatca taaaaatgaa agctaaattt tatgaaggct atattcttta
    10621 ttattctctt cgcttttcaa acctatctta tttatctatc cataagtatc tctgataaaa
    10681 aacaaaagac tattgaatta acatcattga attgttttgt catattattt ctaatctatg
    10741 ataaattaat ttttctcttt attgcctatg tttttttgat aatttttata ttaaacttgt
    10801 tccgtaactg aaaagtgaca tactatatga atacaaaaat gatgtcacaa ttttctgtta
    10861 tggataatga aatgcttgct tgcgttgaag gtggagatat tgattgggga agaaaaatta
    10921 gttgtgcagc aggggttgca tatggcgcaa ttgatgggtg tgcaacaacg gtttgacatt
    10981 tctattggga ccatttgcta taggaatagg tgtaactggt gctgcaggtg gagctatact
    11041 tggaggtgta gcctatgcag caacatgttg gtggtaatta tggattttaa aagttttatt
    11101 attggtttag tagttggtat atttggtcct tatatggatg acttaattag aaaaatattt
    11161 tcaaaatctt ccaaaaagga tacggatagt actctctaaa aaataaattt ctcccctgta
    11221 tttgctagct taatttacag gcgagtttct ttaatattgt ttcgcctgtc aaaatgatat
    11281 gtgatagcag gatgaaaagt ctacaaacaa gttggtatca atacaatata aagaggaaag
    11341 tatgtttttc atgcttgctt ttttaatttt tacaattcaa gaggttttga tgaccattta
    11401 tgatttgagt gatccaaggt caaaataagt gctatactag cagtgtaaat gttcttgctc
    11461 aactaagata aatcgcacat ttaggaggaa atcttatgaa gaaaaaaata ctgattattt
    11521 tcgttctgta tctgatcatg tccatctttc tttatccgct tagggagagt atttggtata
    11581 atctatttta taccatagcc tatatgattg cggttatgat ctatttttct ttaattaaaa
    11641 agaaagaaaa gaaatgaaag attttcttga ttaaaaagaa tcatattctt tgtgagattg
    11701 ttcctgggtc agttgccttt gcttgtttct acttatctat ttctatttcg tcagttttcc
    11761 aatttctttt agtggttatt aacttagctt ctattttggt cactgtttac ctcactaggg
    11821 aaatgcggat aaaagagttt gaagatgatg atttggttag tcctagaacc aatcaactta
    11881 tgttcatcgg cttgacaggc tttatgtcta ttatttgttt gtatagaggg atcacagcag
    11941 gagaatccta ccaacaaata atcgcttata ttggcgctat tctctgcttg accatcatgc
    12001 ttctgctcat ttggggattg aagtattata aaaagtagag gctaatgcag tttttgcaat
    12061 ttaagatgtc ttgatgacaa ttcaagattt ggatgaaaaa ctttgacaaa tagtgctata
    12121 ctgaaattgt caaagttgca acgggtgctg ctacattatg ttaaaaatcg ctcttgattg
    12181 ataagttgga tttgttagga aaggagtaaa taattatgga taagaaaaag atagtttcga
    12241 ctataatatg tatagtattt cttgtagtgt cagtagataa tttttttaga gacttaaccc
    12301 cgttactgtt cattttaaat attattggcc tgtcttgctt ttcagtgcta acatacatta
    12361 acataaaaga gatactctta aatataagta aatgatgatt tggttagtcc tagaaccaat
    12421 caacttatgt ttatcggctt ggcagatttt atgtttgtca tttgtttgta tagaggtatt
    12481 tcagaaacag aattctatca acaactaatc gcttatatag gtgtattctc tgcttgttta
    12541 tcacgcttct gctcatgtgg ggcttgaagt attataaaaa gtagctttct atccttttct
    12601 gacaggatat ttgagtagaa ggctctatta aattgttagt gaaataaatg aatggaggta
    12661 tttaatatga aatacagatt attttttgtt attttcttga gtagtgtgtt ggatattctt
    12721 ttagggacat ttttacaaat ctctatcgta tctattgggt ggcttgttct ttacagtggt
    12781 ttgtttgaag caggagtttt ccttcttgct aataaagggg tggcggtaaa aatcaaggaa
    12841 gtagatattc gaaatcgctt taaatttatt tttggaaaaa ccttatggtt tcaaattctt
    12901 ttgctcatct ttttgataat caaactttat cttggtttgg atgcgaggtt gattttattc
    12961 tatggacata ttttcattgt ctttaatgcc ttaatgtatc tattatctag tagtcaggtt
    13021 agccttaaaa aaaacaaact gtcttcttaa tcttacagca gtagagcctg acaaggtgag
    13081 gtcatagtag ggaggatttc tatgaaaaag tatcaacttc tattcaaaat aagtgcagtt
    13141 ttctcttact tatttttcgt atttggtctt tctcagatga cgcttattat tcaaaattat
    13201 tggcaatttt cttcccagat tggcaatttc gtctggattc aaaatttctt gagtttgcta
    13261 tttagcggag tcatgatttg gattctggtt aagacaggtc atggttatct ctttcacatt
    13321 ccaagaaaaa aatggctttg gtattcgatt ttgacagtat tagtggtagt gctccagatc
    13381 tcttttaacg ttcagacagc taaacatgtt cagtcaactg ctgaaggttg ggctgtattg
    13441 atcggttata gtgggaccaa ctttgctgag ctaggtatct atataacttt gttctttctg
    13501 actccactta tggaagagct aatctataga ggattactgc aacacgcctt ttttaagcat
    13561 tcgagatttg gccttgattt gcttcttccg tcaattttat ttgctcttcc tcatttttca
    13621 agcctgccta gtttgttaga tatcttcatc tttgcaacat ctggcatcat ctttgctagt
    13681 ttgacccgct ataccaagag catttatcct tcctatgcgg tgcatgtgat caataatatt
    13741 ttcgcaacat taccattttt gctgactttt ttacataggg tcttggggta aaaaaacaaa
    13801 aggcttgctt ttcagccata gaggagatta tcatgtataa acacttattt ttcctagatt
    13861 ccaaaacttt agatcggttg acaccctata ttctagtctt ggcttctgac accattgctt
    13921 ttaatgtttt tgtgctaacc tttgtatctg cggtggtttt taatttccta aattccatgc
    13981 tagctttaat ggctatattc ataggggctg gctatgtggt cggattttgg ttactaatac
    14041 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggcaa
    14101 ggcgacgttg acgtggtttg aatttgattt tcgaagagta taaaatggtt tgttttggaa
    14161 aggctagaac taaagaatga cgcgtaggaa gtctgtttgg tgaggaggat agttttatgg
    14221 agttttttga taaatttcat gccttgtgtt ttggattttt agtactaata attgtcatta
    14281 cagttcctta tacgattaac catggggttt tttttcaaaa tgaatctgca ttgattcttg
    14341 taagtcttct tgtaacctcg ctgagtgttg cttatgctag aaagtttgaa atgatttctt
    14401 ttgggatgtt aagcaagaaa caacttttgc ttttcattgc aatctttctt ctaagtgtac
    14461 ttgagacgct ggtttatatt catttcttcg ctgtttcttc tggctcaggg gtccaacact
    14521 tggcggaagt cagcagagga atttccctgt ctttgatttt gactacctca gtttttggcc
    14581 ccatccagga ggaactcatt ttcagaggac ttcttcaagg tgcggttttt gacaattctt
    14641 ggttagggct tgtgctaact tcctctctct tttctttcat gcatggacct tctaatgtcc
    14701 cttcgtttat tttttatcta cttgggggtt tgttgctggg ctttgcttat aaaaagagtc
    14761 aaaacctatg ggtttctact ctagtccaca tgttttacaa cagttggcca ctcctatatt
    14821 atttataaaa attatgaaaa ggtaagcaga agatggtgct tacctttttc aagctataat
    14881 gatacccaag ccaatccaga ggcttttctt tgagaatcgg gttagagtgg ttgacgaata
    14941 ggccaaaaac tagtagaata gtaaggaaac tttatacgga ggaaagaaat ggatttgggt
    15001 gataatgagc taacactgac tcccatacct gggaaaagtg gcaaggctta tatgggtagc
    15061 tatcctgacg ggaagcgcat ctttgtaaaa atgaacacct ctccaatcct acctggtcta
    15121 gctagagaac aaattgctcc acaattatta tggagtcgtc gtttggcaga tgggcgtgat
    15181 atgtgtgctc aagaatggtt gacaggcaag atattgaccc cctatgatat gaatcgtaag
    15241 caaatcgtca atattttaac ccgtcttcat cgctcacgtc cgttgatgac acaattgagt
    15301 cgtttgggct atgccatgga aacacctgta gatttactac agtcttggca ggaaacggct
    15361 ccagatgctt tgcgtaaaaa tcattttatc agtgaagtga tggctgattt acgtcagact
    15421 attccaggat ttagagagga ccatgcgacc attgtccatg gagatgtacg acatagtaat
    15481 tggattgaga cagatagtgg cttgatttat ttagtagatt gggattcggt tcgcttgacc
    15541 gatcgcatgt ttgatgtggc ccatatgctc tgccattata tttcagaaca tcagtggaag
    15601 gaatggttga cctactacgg ttacaagtac aatcaaacgg tattaagtaa attgtattgg
    15661 tatggtcaat tgtcttattt gagtcagatt tccaagtatt atatgaacca agatttagaa
    15721 aatgtcaatc gggagattca tggtttgcgt catttccgag acaagtatgg aaagagaaga
    15781 tgagagttag aaatcgtaaa ggggcaacag aattactaga ggcaaatccc cagtatgtgg
    15841 tcctcaatcc cttggaagcc aaggcaaaat ggcgggactt gtttggcaat gataatccca
    15901 ttcatgtgga agttggaagt ggaaagggtg cctttgtttc aggtatggcc aagcaaaacc
    15961 ctgacatcaa ctatatcggg attgatattc aaaagtctgt tttgagctac gctttggaca
    16021 aggtgcttga agttggagtg cctaacatca agctcttgtg ggtagatggt tctgacttaa
    16081 ctgactactt tgaagacggt gagattgatc gcttgtatct gaacttttca gatccatggc
    16141 cgaaaaaacg ccatgaaaag cgtcgtttga cctacaagac cttcttggat accttcaaac
    16201 gtatcttgcc tgaaaatgga gaaattcatt tcaagacgga taaccgtggc ttgtttgagt
    16261 acagtttagt gagcttttct caatatggca tgaaactcaa tggtgtctgg ttagatttgc
    16321 atgccagtga ttttgaaggc aatgtcatga cagaatacga gcaaaaattc tcaaacaagg
    16381 ggcaagttat ctaccgagtt gaggcagaat tttaagagat agcctaaaat taggctgtac
    16441 aagtgctttt gctttacata agttggcaaa cgtgctatac tgatagtaag aatatgaaaa
    16501 gtgaggcggg gaaatatctt cgcctcttgc ttatgaggag gtggacgcaa tcgcaacaat
    16561 cgtagaatta gtcagagaag ttgtagaacc tgtcatagaa gctccttttg aactcgtgga
    16621 tatcgagtat ggaaagattg gcagtgacat gattctcagt atttttgtag ataaacccga
    16681 aggaattacc ttgaacgaca cggcagactt gacagaaatg atcagtcctg tcctagacac
    16741 catcaagcca gatcccttcc cagaacaata tttcctagaa attaccagtc caggtttgga
    16801 acgtcctttg aaaaccaagg atgccgtcgc tggagcggtt ggaaaataca tccatgtcgg
    16861 gctctaccaa gccatcgata agcaaaaggt ctttgaagga accttgttgg ccttcgaaga
    16921 ggacgagttg actatggaat atatggacaa gacgcgtaag aaaaccgtcc aaattccata
    16981 cagtttagta tcaaaagcac gtttagcagt taaattatag aaaaagaaag gatagctttt
    17041 gaggattcaa aagtgaagaa aacatgagta aagaaatgct agaggccttc cgcattttgg
    17101 aagaagacaa gggaatcaaa aaagaagata tcatcgacgc agtagtagag tcgcttcgtt
    17161 ccgcttatcg cagacgctat ggtcagtcag acagcgtagc tattgacttc aacgaaaaaa
    17221 caggtgactt tacagtttat actgtccgtg aagttgttga tgaagtattt gatagccgtt
    17281 tggaaatcag cttgaaagat gctcttgcca ttaattcagc ttatgaactt ggagacaaaa
    17341 tcaagtttga agaagcacca gctgagtttg gtcgtgtagc agcccaatct gccaaacaaa
    17401 ccatcatgga aaaaatgcgc aagcaaacac gtgccatcac ttacaatact tacaaagaac
    17461 atgagcaaga aatcatgtct ggtacagtag aacgctttga caaccgcttt atctatgtca
    17521 accttggtag catcgaagcc caattgtcaa aacaagacca aattcctgga gaagtttttg
    17581 cttctcatga tcgtatcgaa gtttatgttt acaaggttga agacaaccct cgtggtgtga
    17641 acgtctttgt tagccgtagc catccagaaa tgatcaaacg tttgatggag caagaaattc
    17701 cagaagttta tgatggaact gttgaaatca tgagcgtggc tcgtgaagca ggtgaccgta
    17761 cgaaggttgc tgttcgtagc cacaatccaa acgtggatgc tatcggtaca atcgttggac
    17821 gtggtggtgc taatatcaag aagattacta gcaaattcca cccagctcgt tacgatgcta
    17881 aaaatgaccg catggtacca atcgaagaaa atatcgatgt tatcgagtgg gtagcagatc
    17941 cagctgaatt tatctacaat gccatcgctc ctgctgaggt tgaccaagtt atctttgatg
    18001 aaaacgacag caaacgtgcc ttggtggttg ttccagataa caagctttct cttgccattg
    18061 gtcgtcgtgg acaaaacgtg cgcttggcgg ctcacttgac tggttaccgt atcgatatca
    18121 agtctgctag cgaatttgaa gccatggaag acgctgcttc agtagagttg gaagtagaaa
    18181 acgatactgt agaagaataa aagctgctag aggagggaaa gatgaaaaca agaaaaatcc
    18241 ctttgcgcaa gtctgttgtg tctaacgaag tgattgataa gcgtgatttg ctccgcattg
    18301 tcaagaacaa ggaaggacaa gtctttattg atcctacggg caaggccaat ggccgcggcg
    18361 cttatatcaa actagacaat gcagaagccc tagaggcgaa aaagaagaag gtctttaacc
    18421 gcagttttag catggaagtg gaagaaagct tttatgacga gttgatcgct tatgtggatc
    18481 acaaagtgaa aagaagagag ttgggacttg aataagcaaa agataagtaa tctcttgggg
    18541 cttgctcagc gagcagggcg catcatatcg ggtgaagaat tggtggtcaa ggccattcaa
    18601 gacggcaagg ccaagttggt ctttctagct catgatgctg gacccaatct gaccaagaag
    18661 attcaagata aaagtcatta ttatcaagta gaaattgtaa ccgtgttttc aacactggaa
    18721 ttaagcatag cagtcgggaa atcgagaaag gttttggctg taacagatgc tggatttaca
    18781 aagaaaatga ggtctcttat ggaatagaag aggaggacat gatttgtcta agaaaagatt
    18841 gtacgaaatc gcaaaagaac ttggaaaaga aagtaaagaa gttgtagcgc gtgcaaaaga
    18901 gttgggcttg gatgtgaaaa gccactcatc aagtgtggaa gaagctgtcg ctgcaaaaat
    18961 tgctgccagc tttaagcctg cagctgctcc gaaagtagaa gcaaaacctg cagcaccaaa
    19021 agtaagtgca gaaaagaaag ccgaaaaatc tgagccagct aaaccagctg tagctaagga
    19081 agaggcaaaa ccggctgagc cagttgctcc gaaaacagaa aaagtagcag cgaaaccgca
    19141 aagccgtaat ttcaaggctg agcgtgaagc ccgtgctaaa gagcaggcag aacgacgcaa
    19201 gcaaaataag ggcaataacc gtgaccaaca acaaaacgga aaccgtcaga aaaacgacgg
    19261 ccgtaatggt ggaaaacaag gtcaaagcaa ccgcgacaat cgtcgcttta atgaccaagc
    19321 taagaagcag caaggtcagc aaaaacgtag aaatgagcgc cgtcagcaag aggacaaacg
    19381 ttcaaatcaa gtggctccac gtattgactt taaagcccgt gcagcagccc taaaagcaga
    19441 gcaaaatgca gagtacgctc gttcaagtga ggaacgcttc aagcagtatc aggctgctaa
    19501 agaagccttg gctcaagcta acaaacgcaa ggaaccagag gaaatctttg aagaagcggc
    19561 taagttagct gaacaagcac agcaagttca agcagtggtt gaagtcgtcc ctgagaaaaa
    19621 agaacctgca gtggatacac gtcgtaaaaa acaagctcga ccagacaaaa atcgtgacga
    19681 ttatgatcat gaagaagatg gtcctagaaa acaacaaaag aatcgaagta gtcaaaatca
    19741 agtgagaaat caaaagaata gtaactggaa taacaacaaa aagaacaaaa aaggcaataa
    19801 caagaacaac cgtaatcaga ctccaaaacc tgttacggag cgtaaattcc atgaattgcc
    19861 aacagaattt gaatatacag atggtatgac cgttgcggaa atcgcaaaac gtatcaaacg
    19921 tgaaccagct gaaatcgtta agaaactttt catgatgggt gtcatggcca cacaaaacca
    19981 atccttggat ggggaaacaa ttgaactcct catggtggat tacggtatcg aagccaaaca
    20041 aaaggttgaa gtggataatg ctgacatcga acgtttcttt gtcgaagatg gttatctcaa
    20101 tgaagatgaa ttggttgagc gtccaccagt tgttactatc atgggacacg ttgaccacgg
    20161 taaaacaacc cttttggata ctcttcgtaa ctcacgtgtt gcgacaggtg aagcaggtgg
    20221 tattactcag catatcggtg cctaccaaat cgtggaaaat ggtaagaaga ttaccttcct
    20281 tgatacacca ggacacgcgg cctttacatc aatgcgtgcg cgtggtgctt ctgttaccga
    20341 tattacgatc ttggtcgtag cggcagatga cggggttatg cctcagacta ttgaagccat
    20401 caaccactca aaagcagcta acgttccaat catcgtagcc attaacaaga ttgataaacc
    20461 aggtgctaac ccagaacgcg ttatcggtga attggcagag catggtgtga tgtcaaccgc
    20521 ttggggtgga gattctgaat ttgttgaaat ctcagctaaa ttcaaccaaa atatcgaaga
    20581 attgttggaa acagtccttc ttgtagctga aatccaagaa ctcaaggcag acccaacagt
    20641 gcgtgcaatc ggtacggtta tcgaagcgcg cttggataaa ggaaaaggtg cggtcgcaac
    20701 ccttcttgta caacaaggta ccttgaatgt tcaagaccca atcgttgtcg gaaatacctt
    20761 cggtcgtgtc cgtgctatga ccaacgacct tggtcgtcgt gttaaagttg ctggaccatc
    20821 aacaccagtc tctatcacag gtttgaacga agcaccgatg gcgggtgacc actttgccgt
    20881 ttacgaggat gaaaaatctg cgcgtgcagc aggtgaagag cgtgccaaac gtgccctcat
    20941 gaaacaacgt caagctaccc aacgtgttag ccttgaaaac ctctttgata cccttaaagc
    21001 tggggaactc aaatctgtta atgttatcat caaggctgat gtacaaggtt ctgttgaagc
    21061 cctttctgcc tcacttcaaa agattgacgt ggaaggtgtc aaagtgacta tcgtccactc
    21121 agcggtcggt gctatcaacg aatcagacgt gacccttgcc gaagcttcaa atgcctttat
    21181 cgttggtttc aacgtacgcc ctacaccaca agctcgtcaa caagcagaag ctgacgatgt
    21241 ggaaatccgt cttcacagca ttatctacaa ggttatcgaa gagatggaag aagctatgaa
    21301 agggatgctt gatccagaat ttgaagaaaa agttattggt gaagcggtta tccgtgaaac
    21361 cttcaaggtg tctaaagtgg gaactatcgg tggatttatg gttatcaacg gtaaggttgc
    21421 ccgtgactct aaagtccgtg ttatccgtga tggtgtcgtt atctatgatg gtgaactcgc
    21481 aagcttgaaa cactataaag acgacgttaa ggaagttaca aacggccgtg aaggtggatt
    21541 gatgatcgac tgctacaatg atattaagat ggatgatgtg attgaggcgt atgtcatgga
    21601 agaaatcaag agataagatt ttttgctcct ttcttaggtg gtgagggacg caagcaaacc
    21661 gatggtttca ttgcttattt ttgagcctag ggtctcaaaa atcccctgtg atgggactga
    21721 taaatcagtt ccatcacttt caccacggcg aaagaagcag atgacttcaa attgaacttc
    21781 gtttcaattt aaactgaaaa tcaagaagtt taaaatagct aggtctgctg gcctagcttt
    21841 tggttcaaag tagagaaagg aatatcatgg caaatcattt ccgtacagat cgtgtgggca
    21901 tggaaatcaa gcgtgaagtc aatgagattt tgcaaaagaa agtccgtgat ccacgtgtcc
    21961 aaggtgtgac catcacagat gttcagatgc tgggtgactt gtctgttgcc aaggtttatt
    22021 acaccatttt gagtaacctt gcttcggata accaaaaagc ccaaatcggg cttgaaaaag
    22081 caactggtac catcaaacgt gaacttggtc gcaatttgaa attgtacaaa atcccagatt
    22141 tgaccttcgt caaagacgag tccatcgagt atggaaacaa gattgacgag atgctacgca
    22201 atctggataa gaactaaaga agaggggttg cccctctttt ttggtggagg aaaataggtt
    22261 gaatttgaaa tggaaaaata ttcttttata atagtttgaa actagaatag tacgcctcta
    22321 cttctaaaat attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttcttgtt
    22381 tcattttact ataaaaaagg ggttctgtat tttttaatgt tatctaatta gaaaatgctt
    22441 tttttgtagg aaatataata tgataaggtg caaaaaagaa ataaggagtt tgtatatggc
    22501 tgaacaagac ttagctatgc aagtattgca acaagtggtg aaactacctg ttgttaaggt
    22561 tgatcgttcg aaatttttag tggataagtt ttccaaagaa ttgggtccac aggacattcc
    22621 taccttattg gaacaaggtc caacgtctct cttatctcaa gaaatcttag atcgagtggc
    22681 taatgcctgt attagggata atgttttatt agcgagtggg acttctgttt tggcaggatt
    22741 acctggaggg cttgctatgg caattaccat tccagctgat gtggctcaat tttatggttt
    22801 ctctctgaaa ttggcccaag aattaggtta tatttatggt tatgaggatc tttgggcttc
    22861 acgcgatgag ttgagtgaag atgctcaaaa tacccttttg ctttatctag gcgtcatgtt
    22921 gggggtgaat ggaactgctg ctttgctacg tgctggtggt ataacaattg ccaaacaggt
    22981 aatgaaaaca gtacctaata aagctttaac aaagacgctt tggtatccta ttttgaagaa
    23041 agtcttaaga atatttggtg tgaatcttac caagggaggg ctggccaaag gaatggggaa
    23101 atttattcct atcttgggtg gtatcatttc aggtggttta acctttgcaa ctatgaaacc
    23161 aatgggggaa agcttgcaga aagaattatc caagctagtc aactatagtg aagttcaata
    23221 tcaagaagat gttgaaacaa tccgaaaaga ggctgaaatc atcaaaggag agtaatatga
    23281 atcctatcaa agcttttgct aaaatttatg gtaattactt tttgaccgtg caaggtgtaa
    23341 aagtaatgaa aacgataaag aaagatgata atgccgttgt cggtctgggg aaacttttta
    23401 ttgccgacaa gttaatggat acggctcggt ggctcattaa gccagaggat aaaaaatgaa
    23461 atttttctgg ggacttcttg ccattatttt tatcaaaccg attattggga ttgtgaaatt
    23521 cttttggatg atcatctctt ttgcagtcca attgctgttt tacaagatat tggattggtt
    23581 ctttaaactt atctagatgg taatccaagt cgcagagaac tagcaggaac tccactgcta
    23641 gttttttatt ctctttccat atggtataat ataagcagta aaatcatttt atactcttcg
    23701 aaaatctctt caaaccacgt cagcttcacc ttgctgtata tatgttactg acttcgtcag
    23761 ttctatccgc aacctcaaaa cggtgttttg agctgacttc gtcagttcta tctacaatct
    23821 caaagcactg ttttgagcaa cctgcggcta gcttcctagt ttgctctttg attttcattg
    23881 agtattagaa catataatgg aggtcgtcat ggacaatatc atcgatgtgt caattcctgt
    23941 tgcagaagtg gtggacaagc atccagaagt cttggaaatt ctagtggagt tgggttttaa
    24001 accccttgcc aatcccttaa tgcgcaatac agttggtcgt aaagtatcac ttaaacaggg
    24061 ttctaagcta gcaggaactc ctatggacaa gattgtacgc acactggaag cgaatggcta
    24121 cgaagtgatt ggattagact aatggcagat gaacggattc atgtcctacg ggatatttta
    24181 ttagaattgc ataatggcgc ctctcctgag tcggttcagg agcgttttga tgcgaccttt
    24241 gcgggtgtct cagccattga gatttccctt atggagcacg agctgatgaa ctcggattcg
    24301 ggcgtcactt ttgaagatgt tatggaactc tgtgatgtcc atgccaatct ttttaaaaat
    24361 gctatcaaag gtgtcgaagt ttcagatact gagcatccag gtcacccagt tcgtgtcttc
    24421 aaagaagaaa atctggctct ccgtgcggcc ttgattcgca ttcgtagatt gttagatacc
    24481 tatgagtcta tggaagacga ggaaatgctg gcggagatgc gtaagggttt ggtgcgtcag
    24541 atgggacttg tgggtcaatt tgacatccat taccaacgta aggaagaact cttctttcct
    24601 atcatggagc gctatggaca cgattcacct cccaaagtta tgtggggagt ggatgatcag
    24661 attagggaac tctttcaaac agctctaacg acagccaagt cactaccaga agtgtcaatt
    24721 agcagtgtaa aggaagcttt tgaagctttt gcgacagagt ttgaaagtat gattttcaag
    24781 gaagagtcca tcctgctcat gattctcctt gagtctttta ctcaggatga ctggcttcag
    24841 attgcggagg agagtgatgc ctatggctat gccatcatcc gtccgtcaga gaaatgggtg
    24901 ccagaacgac agatctttat tgaggaaaag attgcagagg agcctgtaca actagatacg
    24961 gcagaaggtc aagttcaaca agtcatagat acgccagaag gccattttac cattaccttt
    25021 acccctaagg aaaaggaagc tgtgctggac cgccatagtc aacaggcttt tggtaatggc
    25081 tatctttcag tcgagcaggc caatctcatc ctcaatcatc tccctatgga gattaccttt
    25141 gtcaataaag aagatatttt ccagtattac aatgacaata cgccagctga tgagatgatt
    25201 ttcaaacgga cgccgtccca agtcgggcgc aatgtcgaac tctgtcatcc gcctaagtat
    25261 ttggacaagg tcaaggctat catgaaggga cttcgtgagg ggaccaagga caagtatgaa
    25321 atgtggttca agtctgagtc gcgaggtaag tttgtccaca tcacctatgc tgcagtacac
    25381 gatgaagacg gagaattcca aggagtgttg gagtatgttc aggatatcca gccctaccgt
    25441 gagattgata cggactattt tcgtggatta gaataaggag aaaaaatgag ttacgaacaa
    25501 gaatttatga aggaatttga agcttgggtc aatacccaaa tcatgattaa cgatatggcg
    25561 cacaaggaaa gtcaaaaagt ttacgaagaa gaccaggacg agcgtgccaa agatgccatg
    25621 attcgctacg agagtcgctt ggatgcttat cagttcttgc ttggtaagtt tgaaaacttc
    25681 aaagtaggca agggattcca tgatttgcca gaaggcttgt ttggtgagcg aaattattaa
    25741 acgagaaaga ttcttgattt ttcactaaaa tcttgataga atgtttatgt taaatccttg
    25801 tcagagcagg gattttttat tgaaaggatt ttatcatgtc aaagaaactc aatcgtaaaa
    25861 aacaattacg aaatggcctc cgtcgcgcag gtgccttttc aagtactgtg actaaggttg
    25921 tagatgagac aaaaaaagtc gtgaagcgtg cagaacagac agcaagcgca gctggtaagg
    25981 ctgtttctaa aaaagttgaa caagcagtag aagctaccaa agagcaagct caaaaagtag
    26041 ctaattctgt agaagatttt gcagcaaatt tgggtggact tccacttgat cgtgccaaga
    26101 ctttctatga tgaaggaatc aagtctgctt cacatttcaa aaactggact gaaaaagaac
    26161 tccttgactt gaaaggaatc ggcccagcta ccatcaagaa attgaaagaa aatggcatca
    26221 agttcaagta atttttcttg agccttgcat ttccgaaaaa atcttgctac aatagagcca
    26281 ttagaggtgt tttgaatccc acattttaca gaaagtggcg gcgctgagaa gtccacaaat
    26341 gtgtcaaaac tggttgctaa tggatgaaaa attgaaataa aagtgtcttt ttgctttaaa
    26401 gacgagagtt gcgggcaact gcccgaaatt gggtggtacc gcggataaac acattcgtcc
    26461 ctgtcatgta gatggcaggg cttttctttt acgtcttagt caaagggggt tgttatgaag
    26521 caatctttta acacaagtaa actatattat ggttttcctg tttttatttt aggatatcaa
    26581 gattagaatt ttggctataa catcacgacc tgtagttcct cttatagtct aggagattgg
    26641 gttgtgattg gagtcgttgc gagagagaat gccgcagagc agatcaaaca gtatcaaaaa
    26701 tttactgtga atatttctga tgaaacttct atgcttgcga tggagcaggc tggttttatc
    26761 agtcatcagg agaaattgga acgtttggga gtgcattatg aaatttctga acgaactcag
    26821 actcctattt tagacgcctg tccacttgtt ttagattgtc gggtagatag gattgttgag
    26881 gaagacggta tttgccacat ctttgccaag attcttgagc gacttgttgc cccagaactc
    26941 ctggatgaaa agggacattt taaaaatcaa ctgtttgccc caacctattt catgggagat
    27001 ggatatcagc gcgtttatcg ctatctggac aagcgtgtag atatgaaggg cagtttcatc
    27061 aaaaaagcga ggaagaagga tggcaagaac tgagctgcca gataaaatcg aaacagaacg
    27121 tctcgtttta cgagtccgta ctgtggcgga tgctgaggat atctttgact atgctagttt
    27181 gccagaggtc gcctatccag caggttttcc tccagtcaag accttggaag atgagattta
    27241 ttatctggag cacattcttc cggagcgtaa tcaaaaggaa aatctcccag caggctacgg
    27301 gattgtcgtc aaaggaacgg ataagatcgt tggctctatc tatttcaacc atcgccatga
    27361 agatgatgtg atggaaatcg gctatacctt acactcagac tattgggggc gaggttatgt
    27421 gccagaagct gcgcgtgcct tgattgactt agcctttaaa gatttgggtc ttcacaagat
    27481 tgaactaact tgctttggat ataaccttca aagtcaacga gtcgcggaaa agcttggctt
    27541 taccctcgaa gctcgcataa gagaccgtaa agatgctcaa ggcaactgct gtgatgattt
    27601 gagatatgcc ttgctgaaga gtgagtgggg ggtgatttga tgcatctttt catcattggt
    27661 gctccagcat caggaaaaat gaccattggt caagaattat ctcgactgac ggatgctacc
    27721 ctattttata accatcaagc cattgatttt gcactagaaa tctatcagga ctatacagag
    27781 gaaatgtggg aatttgttcg tggaatcact ttttcattcc ttggagcaag tgcaagaaat
    27841 cagcgatcag taattttaac agatgtaatt gatttttcaa atcagtatca tctgatatat
    27901 ttaaagcaaa ttcagaattt gttggatgat tatcatcaag agattctttt tgttgagttg
    27961 gaaacaagtc ttgaagagtg catacgtcga aatcgaacgg agaatcgatt aaagcacaaa
    28021 cccttaaaac gacatattga ggtatctgaa agagaaattt tagagaccgc tgaaacactt
    28081 caattaaatt cccaatatca accgaatgag ttgcaccact actttaaaat aaataatacg
    28141 aatttgtctg cagaagaagc tgctaagcaa attcaaaata aaataaacaa aatagagaaa
    28201 ggacacacac atgtctaaag aactttcatc taaatacaat ccagccgagg ttgaggctgg
    28261 tcgttaccaa aaatggcttg atgctgatgt tttcaagcct tcaggcgatc aaaaggctaa
    28321 gccttattca atcgttattc caccaccaaa cgttacaggt aaacttcacc ttggtcacgc
    28381 ttgggataca actttgcaag atattatcat ccgtcaaaaa cgcatgcaag gttttgatac
    28441 cctttggctt cctgggatgg accacgcagg gattgccact caggctaagg tagaggagcg
    28501 cttgcgtggt gagggcattt cccgctatga ccttggtcgt gagtctttct tgacgaaagt
    28561 ctgggaatgg aaagacgaat atgccactac tatcaaggaa caatggggca agatggggct
    28621 ctctgtagac tactctcgtg agcgtttcac tcttgacgaa ggtttgtcaa aagctgttcg
    28681 taaggtcttt gtggaccttt acaagaaagg ctggatctac cgtggtgagt ttatcatcaa
    28741 ctgggaccca gcagctcgca cagccctttc tgatattgag gtgattcaca aggatgtcga
    28801 aggtgccttc taccacatga actacatgct ggaagatggt tcacgcgccc ttgaagttgc
    28861 tacaactcgt cctgagacta tgtttgggga cgttgcggtt gcggttaatc cagaagaccc
    28921 gcgctacaag gacttgattg gtaaaaacgt catccttcca atcgctaata aactcatccc
    28981 aatcgttgga gatgagcacg cagatcctga gtttggtact ggtgtcgtga aaatcacacc
    29041 tgcccacgat ccaaatgact tcttggttgg ccaacgtcat aacttgccac aagtcaacgt
    29101 catgaacgac gacggaacta tgaatgagct tgcctttgaa ttttcaggca tggatcgttt
    29161 tgaagctcgt aaggcagtcg ttgctaagtt ggaagaaatc ggtgcccttg tcaaaatcga
    29221 aaaacgtgtc cattcagtcg gtcactcaga acggacaggt gtcgtagttg agccacgctt
    29281 gtctactcaa tggttcgtca agatggacca attggctaag aacgccattg ccaaccaaga
    29341 cacagaggac aaggtcgaat tctacccacc tcgtttcaac gataccttcc ttcaatggat
    29401 ggaaaatgtc cacgactggg ttatctctcg tcagctttgg tggggtcacc aaatccctgc
    29461 ctggtacaat gctgatggtg aaatgtatgt cggcgaagaa gctccagaag gtgacggatg
    29521 gactcaggac gaagacgtct tggatacttg gttcagttct gccctctggc cattttcaac
    29581 catgggctgg cctgaagttg actcagaaga ctttaaacgt tatttcccaa cttcaacctt
    29641 ggtaacaggt tacgacatca tcttcttctg ggtgtctcgt atgatcttcc agtcattgga
    29701 attcacaggc cgtcaaccat tccaaaacgt ccttatccat ggtctaattc gtgatgaaga
    29761 aggacgtaag atgtctaaat ctcttggaaa tggcattgac ccaatggatg ttattgataa
    29821 atatggtaca gatagtcttc gttggttctt gtcaaacggc tcagctcctg gtcaagacgt
    29881 tcgtttctct tacgagaaaa tggatgcttc atggaacttt attaacaaaa tttggaacat
    29941 ttctcgctat atcctcatga acaatgaagg tttgacgctg gatgtggcgc atgacaatgt
    30001 cacaaaagtt gcaacaggtg aggctggtaa tgtgacggac cgctggattc tccacaatct
    30061 caacgaaacc attgcaaaag ttactgaaaa ctttgataag ttcgagtttg gtgtggctgg
    30121 tcatatcctt tacaacttca tttgggaaga atttgccaac tggtatgttg aattgaccaa
    30181 ggaagtcctt tacagcgaca atgaagacga taaggtcatt actcgatctg ttctccttta
    30241 cactctggac aagatccttc gtctccttca cccaatcatg ccattcgtga cagaggaaat
    30301 ctttggacaa atctcagaag gttctatcgt gacagctgca tacccaactg ttaatctagc
    30361 ctttgaagac cttgcggctc atactggtgt agaaagtctc aaagacttga tccgtgccgt
    30421 tcgtaatgcg cgtgcggaag taaacgtagc accaagcaag cctatcacca tccttgttaa
    30481 gacaagcgat agcgacttgg aagccttctt taacagcaat gtcaactata tcaaacgctt
    30541 tacaaatcca gaacacttgg aaatcgcatc aaccatccct gcacctgaac tggctatgtc
    30601 aagcgtcatt acaggagcag aaatctacct gccattggct gacctcctca atgtcgaaga
    30661 agaactggct cgtcttgaca aggaacttgc taaatggcaa aaagaactgg acatggtcgg
    30721 taagaagctc tctaacgaac gcttcgtagc caacgccaaa ccagaagtcg tccaaaaaga
    30781 acgcgacaaa caagctgact accaagccaa gtatgatgcg accgtagcac gtattgatga
    30841 gatgaagaag ttggtgaaat aaacacagaa acatggtgta atgccgtgtt ttttgggata
    30901 atgaaattac tatctattga tggagaaagt gatgtctaaa cacccgcatt atgaattgtt
    30961 aaatttaatt ggctacggtc ttgccaagtt tgccaagctt tttataaaag aatttcaata
    31021 ttctagtaag tcggagtttt atcgctatgt ggtttctttg ggaattgctg aaacaactgg
    31081 agttgtaaaa aatagaatgg atttatttga tccttatttt gacaatagtc gaaaaggttg
    31141 gtggcagaaa gctgaagttt accgttttcg taaagattta attgatatga tgtttggaaa
    31201 tgaagatgtt catagttatg ttgaaattgt taaaatgtta cttgctagtg aaggaaagca
    31261 aacaggcatt actataattg aaaaaccaat tattcgaact aaattcaaac gtctacagga
    31321 aacggggatg gaggcagaga attattttat ccttcatttt gataaagaag aaaaatttca
    31381 aggtggacag ttaaccgatg catgtcttta tggtgatgga tatgatttcc aagtagatat
    31441 tcaagaacat tcctaccttg ccgaagttaa agggattcga aaacctaagg gtcgtgtccg
    31501 tttaactgcc tacgaatttg agaaagctaa agagtttcaa tcagatttta ttttatctct
    31561 ggtcaccaac ctagatgata ttccaaagtt agtattagtt gataatcctc taaaacattt
    31621 tgagtttaaa aagaatatta taaaaaatga aatcattgaa tatagaagcg tagaggattt
    31681 gtattagttc ccccttaact tttccagttg aaggaacgag aagtcttgac aggtcaacga
    31741 cttaatgaac tggaaatcaa cggtattcgt ttgactaagt tttaagatgg cgaaatcggt
    31801 attgaattta tcagtagtgc tgattataac tcttttatta tttacatgaa gtatatatat
    31861 atcatagaac ctattgtgag gactttttat agtttaagcc agtttccaac caatttcgtg
    31921 atttactggt aatgaagaaa aacaattgaa aggatatttc tatgcaatca acttacaaca
    31981 ttgacaatcc aaacttgtct tatgaagcga agcgtgattt atggcggata ggttttggtc
    32041 tgcagaaagt tgacaatcta gtgccatcag cgtatatgga atctttggct gagaaacagt
    32101 cccggggaga actgacttat gagcaggttt atgaggatgc aacggcttat caccatacta
    32161 ttgatgcaag tacggaagag gcagacttgg tttctctacg tattgtagaa ctattgtctc
    32221 gaagaggctt tagctttagt cctgcgacct tacttgctat tcataaggag ttgtttcaag
    32281 atatatttga accctctatt ccggtggggc aatttcgtca gaccaatatc acaaagaatg
    32341 aacctgtttt gaatggtgaa agtgttgtgt actctgatta ctccatgatt caaatgacct
    32401 tagattatga ttttaatcag gaaaaacaag ttgcatatgc gacactaact caggcggatg
    32461 tggttaaaca aatccagcat tttatttcag gaatctggca gattcatcca tttcgcgaag
    32521 gaaacactcg gacagtaacg gtctttttga ttcagtatct tcgtgagttt ggttttgata
    32581 ttgataatat accatttcag caacattcca agtattttcg tgatgccttg gtattagata
    32641 atgcaaagat tttacagcga cgtcctgagt ttttaacagc tttttttgaa aatctcttgc
    32701 tcggtggtca aaatgatttg tcttcagaaa aaatgtatct agatttagac ctcgattttt
    32761 cataatccaa atactgagta aacattgaat tttaggaaaa aatgaagtaa acattcccac
    32821 aataaaacgc atagtatcaa gtgttaaaat gtactgaccc caaacagtta gacaattaat
    32881 ttatccgaag gatttagttc tgtattgcac agggctaagt ccttttagtt
//
LOCUS       DAVBOM010000022        31746 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBOM010000022 DAVBOM010000000
VERSION     DAVBOM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.022"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            480..1523
                     /locus_tag="VQ878_001085"
     CDS             480..1523
                     /locus_tag="VQ878_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET3095433.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1690..3777
                     /gene="topA"
                     /locus_tag="VQ878_001086"
     CDS             1690..3777
                     /gene="topA"
                     /locus_tag="VQ878_001086"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET3095434.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3883..4242
                     /locus_tag="VQ878_001087"
     CDS             3883..4242
                     /locus_tag="VQ878_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET3095435.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4335..4967
                     /locus_tag="VQ878_001088"
     CDS             4335..4967
                     /locus_tag="VQ878_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET3095436.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            5011..5667
                     /locus_tag="VQ878_001089"
     CDS             5011..5667
                     /locus_tag="VQ878_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET3095437.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5686..6318
                     /locus_tag="VQ878_001090"
     CDS             5686..6318
                     /locus_tag="VQ878_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET3095438.1"
                     /translation="MNFQLAEYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            6346..6780
                     /locus_tag="VQ878_001091"
     CDS             6346..6780
                     /locus_tag="VQ878_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HET3095439.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6792..7829
                     /gene="leuB"
                     /locus_tag="VQ878_001092"
     CDS             6792..7829
                     /gene="leuB"
                     /locus_tag="VQ878_001092"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET3095440.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7826..8095
                     /locus_tag="VQ878_001093"
     CDS             7826..8095
                     /locus_tag="VQ878_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET3095441.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8099..8458
                     /gene="leuD"
                     /locus_tag="VQ878_001094"
     CDS             8099..8458
                     /gene="leuD"
                     /locus_tag="VQ878_001094"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET3095442.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIVAYEKQRPAYWQD"
     gene            8620..9244
                     /locus_tag="VQ878_001095"
                     /pseudo
     CDS             8620..9244
                     /locus_tag="VQ878_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9407..11320
                     /locus_tag="VQ878_001096"
     CDS             9407..11320
                     /locus_tag="VQ878_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET3095443.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            11307..12623
                     /locus_tag="VQ878_001097"
     CDS             11307..12623
                     /locus_tag="VQ878_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET3095444.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12798..13784
                     /locus_tag="VQ878_001098"
     CDS             12798..13784
                     /locus_tag="VQ878_001098"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET3095445.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13848..13919
                     /locus_tag="VQ878_001099"
     tRNA            13848..13919
                     /locus_tag="VQ878_001099"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13881..13883,aa:Arg,seq:ccg)
     gene            14102..14800
                     /locus_tag="VQ878_001100"
     CDS             14102..14800
                     /locus_tag="VQ878_001100"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET3095446.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14791..18330
                     /gene="smc"
                     /locus_tag="VQ878_001101"
     CDS             14791..18330
                     /gene="smc"
                     /locus_tag="VQ878_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET3095447.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAVSPGFLGMADELVTFDTRLEAIFKNLLDTT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMATLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEKDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPQGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18327..19121
                     /locus_tag="VQ878_001102"
     CDS             18327..19121
                     /locus_tag="VQ878_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3095448.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            19121..19939
                     /locus_tag="VQ878_001103"
     CDS             19121..19939
                     /locus_tag="VQ878_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3095449.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKSTLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISLELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKVAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19943..21232
                     /gene="ftsY"
                     /locus_tag="VQ878_001104"
     CDS             19943..21232
                     /gene="ftsY"
                     /locus_tag="VQ878_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET3095450.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDLTFTEADEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21276..22763)
                     /locus_tag="VQ878_001105"
     CDS             complement(21276..22763)
                     /locus_tag="VQ878_001105"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET3095451.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     VELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(22912..23652)
                     /locus_tag="VQ878_001106"
     CDS             complement(22912..23652)
                     /locus_tag="VQ878_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3095452.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23652..25817)
                     /locus_tag="VQ878_001107"
     CDS             complement(23652..25817)
                     /locus_tag="VQ878_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3095453.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            25990..26943
                     /locus_tag="VQ878_001108"
     CDS             25990..26943
                     /locus_tag="VQ878_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3095454.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            27020..29008
                     /gene="uvrB"
                     /locus_tag="VQ878_001109"
     CDS             27020..29008
                     /gene="uvrB"
                     /locus_tag="VQ878_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET3095455.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            29018..29581
                     /locus_tag="VQ878_001110"
     CDS             29018..29581
                     /locus_tag="VQ878_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095456.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREGWEKINDGYYQINGNS"
     gene            29547..30035
                     /locus_tag="VQ878_001111"
     CDS             29547..30035
                     /locus_tag="VQ878_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095457.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDDTIQAGGIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            30109..30576
                     /locus_tag="VQ878_001112"
     CDS             30109..30576
                     /locus_tag="VQ878_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3095458.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30573..31088)
                     /locus_tag="VQ878_001113"
     CDS             complement(30573..31088)
                     /locus_tag="VQ878_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET3095459.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31100..31627)
                     /locus_tag="VQ878_001114"
     CDS             complement(31100..31627)
                     /locus_tag="VQ878_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3095460.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT         9830 a         5620 c         7052 g         9244 t
ORIGIN      
        1 actgttatag attcaataca ctataattta gtgtaattga gaaaggagaa atgattgtga
       61 ttgatgttgg ctaggttatg ttcaatgatt cctaccgtct caaatcttgt cagtaaggaa
      121 aaataaattc ttcaaaagta gagattacaa ggtttgttta agaaagaatt caaagacctt
      181 gacaaataaa aataaaatgg ttattataag aaatggtcta aaatagatga tgatactttt
      241 cgaaaatctt tttacgtcag ctcagctttg ccttgctgtg ttttgagcaa gctacggtta
      301 gcttccgagt ttgattttca tttactagaa atgaaactga tgagagatat cagtagacat
      361 ttgagtcagg atattatgga aaatgataaa aagagctcgt gagattggca tatcagacta
      421 ctaaagtatt gagtttgtta ggattttagc gactagttag ctgggaaagg aagatatttg
      481 tgacaaataa taaactgtat tcgttgatag aatttagaaa taaaatatat gaagaattag
      541 aactttccag aagtgattta gcgattttac tatgtgccat gcttatcgcc tctatcggat
      601 taaatatgga ttcgactccc gtgattattg gagccatgtt aatctctcct ttgatgacac
      661 ctattctggg agtggggctc tctctagcta tatttgattt taaattgtta agaaaatctt
      721 ttaaaatatt agctattcaa attcttgcca gtctaatagc ttcaacactt tatttttatc
      781 tttctcccat ttcgtatgct agttcggaga ttgttgctag aacctctccg actatttggg
      841 atgttctcat tgcttttgta ggagggatag caggtattat tggtgctagg aaaaaagaga
      901 ccaataatat tgttcctggt gttgctattg caaccgcctt gatgcctcct ctttgtacag
      961 taggttatgc tattgcttct gctaatctaa aatttatcat aggctcctct tacctattcc
     1021 tcatcaattg tagctttatt gtcattgcga cttatatagg tgttaggttg atgatggtta
     1081 agaaacatta ttttaaagat aatgaagaag actctaaaat gcgtaggatt ttgcttctag
     1141 ttgctgtttt gctgatgatt ccgagtttca tctctgcaac gactttagtg agagaaacgt
     1201 tgaaaaaaga gtcccttaag aaatttatat cagagcagtt tcaggggcat aatattttga
     1261 aaaaaaccta ttctaaaaag actcataccc taaagctaac catctcagga aattatttga
     1321 cagaagaaga actcgatatg atttcaagta agagaggtga ctatggttta agtgatgttt
     1381 ctgttcaagt ttcacaattg tctgattcag aacaacttag taaggaagag ctggtggagt
     1441 atttcttcca gtatatcaag gataaggaag caaaagaaaa ggagaaagct aataaatttg
     1501 atacagagtc tgaggagcaa taatttcttg agaatagctg gtttctctcg tgagtcttct
     1561 atgtatatca aaggaagact gaggttttaa gtataaaact tttcttctat tatagtagct
     1621 aagtcttgac agggttcaaa aaatggttta cactttataa agtttattac tttgaaaagg
     1681 tgtgatactg tggctacggc aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc
     1741 atcgtggagt cgcctgctaa ggccaagacg attgaaaaat atctaggcag aaactacaag
     1801 gttttagcca gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt
     1861 gaaaataatt atgaaccgca atatattaat atccgaggaa aaggccctct tatcaatgac
     1921 ttgaaaaaag aagctaaaaa agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa
     1981 ggagaagcga tttcttggca tttggcccat attctcaact tggatgaaaa tgatgccaac
     2041 cgtgtggtct tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa agaacctcgt
     2101 aagatagata tggacttggt cgatgcccaa caagctcgtc ggatcttgga tcgcttggta
     2161 gggtattcga tttcgcctat tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc
     2221 gttcagtcca ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa tgccttccag
     2281 ccagaagaat actggacagt tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct
     2341 tccttctatg gagtagatgg taaaaagatg aaactgacca gcaatgatga agtcaaggaa
     2401 gtcttgtctc gtctgacgag taaagacttt tcagtagatc aggtggataa gaaagagcgc
     2461 aagcgcaatg ctcctttacc ctataccact tcatctatgc agatggatgc tgccaataaa
     2521 atcaatttcc gtactcgaaa aaccatgatg gttgcccaac agctctatga aggaattaat
     2581 atcggttctg gtgttcaagg tttgattacc tatatgcgta ccgattcgac tcgtatcagt
     2641 cctgtagcgc aaaatgaggc ggcaagcttc attacggatc gttttggtag taagtattct
     2701 aagcacggta gcaaggtcaa aaacgcatca ggtgctcagg atgcccatga ggctattcgt
     2761 ccgtcaagtg tctttaatac accagaaagc atcgctaagt atctggacaa ggatcagctc
     2821 aagctatata cccttatctg gaatcgtttt gtggctagcc agatgacagc ggccgttttt
     2881 gataccatgg ctgttaaatt gtctcaaaaa ggggttcaat ttgctgccaa tggtagtcag
     2941 gttaagtttg atggttatct tgccatttat aatgattctg acaagaataa aatgctacca
     3001 gatatggctg ttggagatgt ggtcaaacag gttaatagca aaccagagca acatttcacc
     3061 caaccgcctg cccgttattc tgaagcaaca ctgattaaaa ccttagagga aaatggggtt
     3121 ggacgtccat caacctatgc gccaaccatt gaaaccattc agaaacgtta ttatgttcgc
     3181 ctggcagcca aacgttttga accgacagag ttgggagaaa ttgtcaataa gctcatcgtt
     3241 gaatatttcc cagatatcgt aaacgtgacc ttcacagctg aaatggaagg taaactggat
     3301 gatgtcgaag ttggaaaaga gcagtggcga cgggtcattg atgcctttta caaaccattc
     3361 tctaaagaag ttgccaaggc tgaagaagaa atggaaaaaa tccagattaa ggatgaacca
     3421 gctggatttg actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt
     3481 aaattctacg cttgtagcaa tttcccagat tgccgtcata cccaagcaat cgtgaaagag
     3541 attggtgttg agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt
     3601 aatcgccttt tctatggttg caatcgctat ccagaatgtg aatttacctc ttgggacaag
     3661 cctgttggtc gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa agtccgtggt
     3721 ggtggcaagc aggttgtttg tagcaaaggc gactacgagg aagaaaagat taaataagag
     3781 gaggggcccg aaagtaaatt tcaggctcct tttggttaga acttgacaaa atacatcatt
     3841 ttatgcgaaa ctagaagaag attattttaa ctaggagaag ttatgcgtct tatctatctg
     3901 ataattggtt ttttatcact ggccttggct attgttgggg ttgttttacc cttgttgccg
     3961 acaacgcctt tccttttgtt gtctattgct tgtttctcca gaagttccaa gcgtttcgaa
     4021 gactggcttt atcataccaa gctctatcaa acatatgtag ctgattttcg cgagactaag
     4081 tctattacgc gtgaacgaaa gaaaaaaatc atcgtctcta tctacgtctt gatgggaatt
     4141 tctatttatt ttgcacctct tttaccagtc aaaatcggtc tgggtgcttt gaccatcttt
     4201 atcacttatt atcttttcaa ggtcattcca gacaaagaat agttaaaaca gtagttattt
     4261 gccttgataa aattgaaagc atattcataa taatatgata taataaattt gaagtaatat
     4321 tcaaggagaa tcaaatgatt tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag
     4381 cgatgcaggc tggagctcgt cggattgaac tctgtgataa tctagcagtt ggtgggacaa
     4441 cacccagcta tggagtgact aaggcagcgg ttgaactggc agctaactac gatacaacca
     4501 tcatgaccat gattcggcca cgtggtggtg actttgtcta taatgaccta gaaattgcta
     4561 tcatgctaga agacattcgt ttgactgctc aggctggaag tcaaggggtt gtatttggaa
     4621 ctttaactgc tgataaaaag ttggataagc ctaatctgga aaagttaatt gctgcatcaa
     4681 aaggaatgga aattgtcttt cacatggcct ttgatgaact aagtgatgaa gatcaaccgg
     4741 aagctattga ctggctcagt caagccggtg tcactcgtat cctaactcgt gctggtgtgt
     4801 ctggcgactc cttagaaaaa cgttttgttc actatcacag aattttggag tacgctaaag
     4861 gtaaaattga aattctacca ggtgggggga ttgaccttga aaaccgtcaa acctttatcg
     4921 accaggtggg ggtaacacaa ttgcatggta ctaaggttgt tttttaaaaa atagaaagga
     4981 actgctagct ttgggtagca gttttcactt atgtttgaaa tttttaaatc ctatcaattt
     5041 aatcaagaaa aggctcatga ttatggtttt atagaaaata gcgaagtctg gacatatagt
     5101 tgccagattt tgcaaggtga ctttgtcatg actgtgtcca tcactgctga taatgtgaac
     5161 tttcaagtct ttgaccaaga gactggtgac ctctatcctc acgttcatat ggaaagcatg
     5221 aggggaagtt ttgtcggaaa tgtccgtgag gcttgtctgg agattcttta ccagattcgg
     5281 aaggcttgtt ttgatgtgca agattttatc tgtcatcaga ctaagcgtat catgactcaa
     5341 gttcaggaaa agtatggaaa ccagttggag tatctgtggg aaaaatcgcc tgatacagct
     5401 gtattgcgcc atgaaggcaa tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat
     5461 aagctggaaa agggcagaga aggacaagtg gaagcagtca acctcaagca tgaccaagta
     5521 gctaatttgc tttcacaaaa ggggatttat ccagccttcc atatgagcaa gcgctactgg
     5581 attagtgtgt cccttgatga tactttatca gatgaagaag tactggaatt gatagaaaaa
     5641 agttggaact taacctctaa aaaatgaaat attttaataa ttttcatgaa ctttcaatta
     5701 gctgaatatt ctttactgaa gaaattttca gaaaatatag gatttaccac accagaggaa
     5761 tgtggtgcca tcttcaaata cctgattgag aatgtcaaga cggatcgtca gatcatctat
     5821 tcgcctcact gtcatgatga cctcggaatg gcagtggcaa atagccttgc tgctgtcaag
     5881 aatggtgcag gacgtgttga agggactatc aatggtatta gggagcgagc tgaaaatgct
     5941 gctttggaag aaattgcagt ggctctcaat attcgccaag attactacca agtagaaacc
     6001 agtattgtcc taaatgagac catcaatacg tcagaaatgg tttctcgctt ctctggtatt
     6061 ccagttccta aaaacaaagc cgtcgttggt ggcaatacct tctcccacga atctggtatt
     6121 caccaagatg gagtccttaa aaatcctctc acttatgaga tcatcacacc tgaattggtt
     6181 ggtgttaaga ttccgcttgg aaaattatct ggtcgccatg cttttgttga gaaactgaga
     6241 gaattggccc tagattttac agaagaggat atcaaaccac tctttgctaa gttcaaggca
     6301 ctggccgata agaagtaaga aatcacagat gcagatactc gagctttggt agctggaacc
     6361 atggttgaaa atccagaagg cttccacttt gatgatttac aacttcaaac tcatgcagat
     6421 aatgacattg aagcgctcgt tagcctagcc aatatggatg gtgagaaagt cgaatttaat
     6481 gcgacagggc aaggttccgt tgaagcaatc tttaatgcta tcgataagtt ctttaaccaa
     6541 tctgttcgtt tggtgtccta cactatcgat gcggtaacag atggaatcga tacccaggat
     6601 cgggttttgg tcactgttga aaacagagat acagaaacca tctttaatgc agcagggctt
     6661 gattttgatg tgttgaaggc ttctgctatt gtctatataa acgctaatac ctttgttcaa
     6721 aaagagaatg caggtgagat gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa
     6781 aggagaaggc tatggcaaag aaaatagtag ctctagcagg agacggaatt ggcccagaaa
     6841 tcatggaggt tggtttagaa gttctggagg ctctagctga aaaaacaggt tttgactatg
     6901 agattgacag acgaccgttc ggaggtgcag atattgatgc agcaggacct cccttacctg
     6961 atgaaaccct taaggcaagt agggaagcag atgctatcct actagcagct atcggtagtc
     7021 ctcagtatga tggagcagtg gttcgccctg aacagggcct gatggctctc cgtaaggaac
     7081 tcaatcttta cgctaatatt cgtcctgtaa aaatctttga cagtctcaag tatttgtcac
     7141 cactcaaact ggaacgaatt gctggtgtag actttgtcgt ggtgcgtgaa ttgacaggcg
     7201 ggatttactt tggagatcat attcttgaag agcgcaatgc gcgtgatatc aacgactata
     7261 gctatgagga agtggagcgg attattcgca aagcctttga aattgcaaga aatcgcagaa
     7321 aaatccttac tagtatcgat aagcaaaatg ttctagcgac ctcaaaactc tggcggaaag
     7381 tagctgagga agtcgcacag gatttcccag atgtaacctt ggaacaccag ctggtagact
     7441 cagctgctat gcttatgatt accaatcctg ctaagtttga tgttattgta acggagaatc
     7501 tttttggaga tattttatct gatgaatcaa gcgtcttatc tggtacactt gaggttatgc
     7561 catcagccag tcattctgaa aatggaccaa gtctctatga acctattcac ggttcagcac
     7621 ctgatattgc aggtcaagga attgccaatc ctacttccat gattttatca gttgccatga
     7681 tgttgagaga tagtttcgga cgttatgagg atgcagagcg tatcaaacgt gctgttgaga
     7741 caagtctggc ggcaggaatt ttaacgagag atataggagg tcaggcttca acaaaggaaa
     7801 tgacggaagc tattattgca aggttatgaa gttagacgaa aaaattactc tagtcctttt
     7861 gatttggaat gtcatcattt tcttgattta tggcattgac aaattcaagg caagaagaag
     7921 agcttggcgc atcccagaga aaatcttact cattttagcc cttacttgtg gtggttttgg
     7981 ggcctggtta gctggaatta cttttcacca caagactcga aaatggtact ttaaaacagt
     8041 ttggtttctt gggatggtga ccacactagt agccttatat tttatttgga ggtaatggat
     8101 ggcagggtct tcgagggaac acgctgcttg ggctctagcg gactatggtt ttaaggtcgt
     8161 gattgcagga tctttcggtg acattcatta caataatgaa ctcaataatg gcctgttgcc
     8221 aatcgttcag cctagagagg ttagagagaa attagcccag ctaaaaccaa ccgaccaggt
     8281 aactgtggac ttggaacaac aaaaaatcat ctcaccagtt gaagaattca ccttcgagat
     8341 agatagcgag tggaaacata aactcctaaa tagtttggat gatatcggta ttaccttgca
     8401 gtatgaagag ttgattgttg cttatgaaaa acaacgacca gcctactggc aggattagaa
     8461 aaaatagaaa aggaaatata gtaaactgaa ataagatgta aacaaatgaa ttagagctta
     8521 acatccattt ccagcaattt tttagaaact acagtggact attctggatt caacacatta
     8581 taaaattatg acaaaacaca ttcacaagaa ggctacgaca ttttaaaagg tgagggcgga
     8641 tgtatcgttt gccctactaa agttggttac attatcatga ccagcaacaa ggcaggactt
     8701 gagcgtaagt tcgcagccaa agaacgtaag cgtaacaaac caggtgttgt tctctgcggt
     8761 agcatggatg aactttgcgc tttagcgcaa ctcaacccag aaattgaagc attctactaa
     8821 aaacattggg atgaagatat tcttcttggt tgtatccttc cttggaaacc agaagtcttt
     8881 gaaaaactca aagcatacgg ggatggccgt gaagaactta tgactgatgt acgtggtact
     8941 agctgttttg ttatcaagtt tggaaaagca ggtgaacaat tggctgccaa gctttgggaa
     9001 gaaggtaaaa tggtctacgc ctcatctact tcaatgacaa aacgattgaa actcgctatg
     9061 agagcaaggt gtaatggtgt ctatggtcga taaggacggc aaactcatcc cagaacaagg
     9121 aggagcacgt tcaacctcac cagcaccagt tgtgatccgt aaagggcttg acattgataa
     9181 aatcatgatg cacctgtcag atacttttaa ctcatgggac taccgtcagg ttgagtatta
     9241 ttaggataga gaagaagtct agtgttaagg acattacagc tcataatact aggctttttt
     9301 atagaaattc ttttcttttt ctataggata tggtattcta tgtagaaaat atatgttaat
     9361 aagtaatgcc aatatttaaa catcattagt aaaaggagtt agattgatga ataaaagaaa
     9421 agttagttta gaagattttt ataaatggta tagtctaaat aaagaagagt tattaaataa
     9481 ggcaactgtt ggtgaaaagt ttaatgataa attaaaagaa gagtttctcc aggaatggcc
     9541 tttggatagg attttaacaa tgtcaatcga tgaatatgta ataggaaagg gacagcaaaa
     9601 taagtcttta tgctacgctc ttgagaaggg aaaatacaaa aatctatttc ttggaatttc
     9661 tggtggctca gcttcaaaat ttggtattta ttggaataaa aaaacaaaca aatataaaga
     9721 tcaagctaat aatgagattt cagagttgga tcagcgattt tcaaaattaa aatcagattt
     9781 gtatgaaatt atcaaagaag gtattcgttt taactttgaa aatcctattt ttgatatgaa
     9841 aagatcaaca aatgaattta ttggtcgttc tgctatggtg acaaaattac tttgtatcta
     9901 ttctggggga gatcctttct ttggtgtaaa tattaatagt cagaaagaat tttggaacca
     9961 ctttgtttct cagacaaatc aaggtggacc ttatctgcaa aatcataaaa taattgaact
    10021 ggtgtccaaa acttatcctg agttggagcc atcgaaatta ggaactatgc tttttgagta
    10081 ttctaagctt tttatggaaa ataaggaaga caatagtaca atggattcat caaacaattt
    10141 tcgtcatcaa ttaactcaat ctctattaaa gtctccaaac cttatccttc gtggtgctcc
    10201 tggcacagga aagacttatc ttgctaaaga aattgccaaa gaattaacgg atggcaacga
    10261 agaccaaatc ggatttgtac aatttcaccc atcctatgat tatacggatt ttgtagaagg
    10321 tttaagacca gtatcaaatg gggatggagc tattgagttt aggctacagg acggtatttt
    10381 taaagatttt tgtcagaaag caaaagaaac ccaattgatt ggaggacaag ataattttga
    10441 tgaggcttgg gattcttact tagaatatat aaatgttgct gaagaaaaag aatatataac
    10501 aaaaacatct tacttatctg ttaatagtag acaaaatttg tcagtaaatt atgatagtgg
    10561 tgttccagga tggtcactac ctagcaaata tgtttacgag ttgtataaag ataaaaatta
    10621 taataagcaa gaatactaca aaagtggtgg aaaaactgtc ctagaaacat tgagaaagag
    10681 atttggtttg aaagactatg tttccccaac agaaattgat actgataaga aattcgtctt
    10741 catcatcgat gaaatcaatc gtggggagat ttctaagatt tttggcgaac tctttttctc
    10801 tatcgaccct ggctatcgtg gtgaaaaagg aagtgtttct acccaatatg caaatctaca
    10861 cgaaactgat gaaaagttct atatccccga aaatgtttac atcatcggaa ctatgaatga
    10921 tattgatcgt tcagtggata cctttgattt tgctatgcgt cgtcgttttc gttttgttga
    10981 agttactgcc gagggtcaag ttggcatgtt ggataaagag ctgaatatcc atgcagaaga
    11041 agcaaaaatt cgtctaagaa acttgaacgc tgctatcgaa aatgttcagg aattaaacag
    11101 tcattatcat attggaccaa gttattttct taagttgaag gatgtagatt ttgactatga
    11161 attactctgg tccgattata ttaagcctct cctagaagac tacttgcgag gttcttatga
    11221 tgaggttgaa actttggaaa ctttgaaaaa agcatttgaa ctgacaaata atgatcaaac
    11281 tggtcaacaa gatactggtg ataatgatgc ggattactga taatcaatac aagattatta
    11341 aagaaaaatt tgttgaagaa tatccgaaac taagcaatct tcttttagac agaaccttgg
    11401 aaagtctatc ccaagatgaa cgtattttca tttttccaaa tgatttgact catactcctg
    11461 atttggataa ggaccaaaag atttttgaaa cagtcaatca gaaaatcaag acagggaacg
    11521 tgattggttt tcttggatat ggtcaggaaa gattaacgat ttcctcacga ttttctgatg
    11581 agagtaatga ccattttttg cattatctct taaacaaggt tcttcatatc aatctcacta
    11641 gtttagatgt tgctttgtct cgtgaagaga ggctttatca acttttgatg tatctcttcc
    11701 ccaagtatct acaagctgct attcgaaaag gtctttataa ggaataccag agattttctc
    11761 ataacgacag tcatgttaag ggagtgattg atgtaagaaa ccatctcaag aaaaatcttc
    11821 ctttcacggg aaatattgcc tacacaacga gagagttcac ctatgataat cccctcatgc
    11881 agttggtccg tcacactatt gaatacatta agaatcagaa aagcattggt caaggggtac
    11941 tagataatct ctcaactagt cgtgaaaacg tatctgaaat cgtgcgtgta acgccctctt
    12001 ataaactagc tgatcgtgct aagattattc ggggaaatca atctaaacct atacgtcatg
    12061 catactttca cgagtacaga aacttacaag aactttgtct gatgatccta aaccaagaaa
    12121 agcacggttt agggtatcaa gatcaaaaaa tctatggtat tctctttgat gttgcctggc
    12181 tttgggaaga gtatgtttac accttgttgc caaaaggttt tgtacatccc agaaataagg
    12241 ataagacgga tggaatttca gtattttctg ttgggaaacg aaaagtatat ccagattttt
    12301 atgacagaga acgaaagatt gttctagatg caaaatataa aaaactggaa ttgactgaaa
    12361 aaggaatcaa ccgtgaggac ttattccagc tgatttccta ttcttatatt ttaaaagctg
    12421 agaaggctgg actgattttt cctagtatgg agcagtcagt aaatagtgaa ataggaaaag
    12481 tagctggcta tggagctcaa ttgaagaagt ggtctattcg aatccctcag aatgcctcat
    12541 tctatagtac attttgtaaa atgatggaaa attcagaaga aaattttaaa gcgattattg
    12601 atgaagaagt ggggagaaaa taatttcccc tctttctttt atttttaaca caagtaaaac
    12661 ccgaacgata tattttaatt cataaaataa tttgacaaaa actgtacttt ggtttataat
    12721 aaattaagga aacgtcggaa aaggcgtagt gatgcaagag cataggtagg tcattacaaa
    12781 agaaacgaga catcgatatg ttaaatgaat ttccaatttt tgattacgaa gatattcaat
    12841 tgattccaaa taaatgtgtc attaaaagcc gtgcagaagc ggatacaagt gtcactttag
    12901 gaaatcacac ctttaaacta cctgttgtgc cagcgaatat gcagacgatt ttggatgaaa
    12961 atgtagcaga gcaactggct aaaggtggtt acttctacat tatgcaccgt tttgatgagg
    13021 caggacgcat tccttttatt aaacgaatgc acgatcaagg gctcattgct tctatctctg
    13081 tcggtgttaa ggattatgag tatgatttcg ttagacagct caaagctgat gctcctgagt
    13141 atatcactat tgatattgct catggtcatg cggatagcgt gatttctatg attcaacaca
    13201 tcaagaaaga attgccagat acctttgtca ttgctggaaa tgtgggaaca ccagaagctg
    13261 tgcgtgaatt ggaaaatgct ggtgcggatg ctactaaggt cggaatcggt cctggtaagg
    13321 tttgtatcac caaggttaag actggttttg gtacaggtgg ttggcagttg gctgctctac
    13381 gctggtgtgc caaggctgcg cgtaaaccga ttatcgctga tggaggaatt cgtactcacg
    13441 gtgatattgc taagtctatc cgcttcggtg ctagcatgat catgattggt tccctctttg
    13501 caggacacat tgaaagtcca gggaaaacga ttgaagtcga tggtgaacag ttcaaagaat
    13561 attatggttc agcctcacaa tatcaaaaag gtgcttacaa aaatgtggaa ggcaaacgta
    13621 tcttgcttcc tgctaaaggt catctgcaag acactttaac tgagatggaa caagaccttc
    13681 aaagtgctat ttcttatgca ggtggacgtc aggttgctga ccttaaacac gttgattatg
    13741 tgatcgtgaa aaactccatc tggaatgggg atgcttccca ctaagacggg gtctttgacc
    13801 aaaaaacttg ttattagagc aaatttctgt tataataaaa caagtttcca cccttagtgt
    13861 aatggatatc acgtaagatt ccggttcttg agatgggggt tcgattccct cagggtggat
    13921 gtaaacatcc taaaaagcct ttaatagggc ttttttcttt atcctgaccc aaatttgccg
    13981 ctaaaactga gaatctctgt ctaaagaatt cccaaatgct ttccagtccc gttttagagt
    14041 gactcagggg gctttttttg atataataaa aaggactatt atcagttaga aagaggttgg
    14101 tatgaaagaa ttacaaactg tactaaagaa tcattttgca atcgaatttg cagacaaaaa
    14161 tttactggaa actgccttta ctcatacgag ttatgccaat gagcaccgcc tcttaaaaat
    14221 ttcacacaat gaacgcttgg aatttttagg agacgctgtt ctacagttat tgatttcaga
    14281 atatctatat aaaaaatatc ctaaaaagcc tgaaggtgac ctatcaaaac tccgtgctat
    14341 gattgtccgt gaggagagtt tagctggttt tgcgcgtgat tgccagttta accagtttat
    14401 caagttgggt aaaggggaag aaaaatcagg tggtcgcaat cgtgacacca ttcttggtga
    14461 tgcctttgaa gcctttcttg gtgcccttct tttggataag gatgtggcca aggtcaagga
    14521 atttatctat caagtcatca ttcctaaggt tgaagcaggc gagtttgaga tgattacaga
    14581 ctataaaacc catctccaag agttgcttca ggtcaatggt gatgtggcta ttcgttatca
    14641 ggtgatttct gaaacagggc ctgctcatga taaggtcttt gatgtagaag ttcttgttga
    14701 aggtaagagc atcggtcaag gccaaggtcg ttctaagaaa ttagcagagc aggaagctgc
    14761 caaaaatgcc gttgagaagg ggctggattc atgtatttaa aggaaatcga aattcagggg
    14821 ttcaagtctt ttgctgataa gaccaaggtc gtttttgacc aaggtgtgac ggcagttgtt
    14881 ggacccaatg gatctggaaa gtccaatatt acagaaagtc tgcgttgggc tttgggggag
    14941 tctagtgtca agagtctccg tgggggcaag atgccggatg tcatctttgc tggaaccgaa
    15001 agtcgcaaac cgctcaatta tgcttctgta gttgtgactc tggataatca tgacggattt
    15061 atcaaggatg caggtcaaga aatcagggtg gaacgccata tctatcgtag tggagatagc
    15121 gaatacaaga ttgacggcaa gaaagtccgt ctgcgtgata ttcatgacct cttcttggat
    15181 actggattgg gacgagattc cttctctatt atttcccaag ggaaggttga ggagattttt
    15241 aattccaagc ctgaggaacg acgagctatt tttgaagaag ctgctggagt tttaaaatac
    15301 aagactcgca gaaaagaaac cgagagtaaa ctgcagcaaa ctcaggataa tctggaccgc
    15361 ttagaggaca ttatctacga gttggataat caaatcaagc ctcttgagaa gcaagctgag
    15421 aatgcccgta agtttttaga cttggaagga caacgtaagg ctatttattt agacgttctg
    15481 gttgctcaaa tcaaggaaaa taaggctgaa ctagagtcga cagaagaaga gttgactcag
    15541 gttcaagaac tcttgatgag ttattaccaa aagcgtgaaa aattagaaga agaaaatcaa
    15601 actcttaaaa agcaacgcca agatttacag gctgaaatgg ccaaagacca aggcagtttg
    15661 atggacttga ctagtctgat tagtgattta gaaagaaaat tagccctatc gaaactggag
    15721 tccgagcaag tggccttgaa tcaacaggag gcacaagccc gtttggctgc tttggaggat
    15781 aagagaaatt cactcagcaa agaaaagtct gataaagaaa gctctttagc tctgttagag
    15841 ggaaatctag tccaaaataa tcaaaaactc aatcgtttag aagctgaatt gctggctttt
    15901 tcagatgatc ctgatcagat gattgagctt ttgcgtgaac gctttgtggc gcttttacaa
    15961 gaagaagcgg atgtctcaaa ccaactgacc cgcatcgaga atgagttgga aaatagtcgt
    16021 cagctttctc aaaaacaagc agatcaacta gaaaagctga aagagcaatt ggctatagct
    16081 aaagagaagg ctagtcagca aaaggaagag cttgaaactg ccaaggagca ggttcagaaa
    16141 ttattggctg actatcaagc tattgccaag gagcaagagg agcaaaaaac ttcctatcaa
    16201 gctcaacaaa gtcaactctt tgaccgtctg gatagtctta aaaacaagca ggctagagct
    16261 caaagtttgg aaaacatcct tagaaatcac agtaactttt atgcaggtgt aaagagtgtt
    16321 ctccaagaaa aagaccgcct tggtgggatt attggtgctg ttagtgagca tttgaccttt
    16381 gatgtgcatt atcaaactgc cttagagatt gcacttggag ccagcagtca gcatatcatc
    16441 gtagaagatg aagagtcggc aaccaaagct attgatttcc ttaaacgaaa cagagccggt
    16501 cgtgcaacct tccttccgtt gacaacaatc aaggctcgta cgatttctag ccagaatcaa
    16561 gatgttatcg ctgtaagccc aggtttcctt gggatggcag atgagttggt gacttttgat
    16621 actagactgg aagccatttt caagaatttg ctagatacga cggctatttt tgatactgta
    16681 gagcatgcgc gtgcagcagc tcgccaagtt cgttatcagg ttcgtatggt gacattggat
    16741 gggacagaat tacgcacggg tggttcctat gcgggtggtg ccaatcgcca aaataacagt
    16801 attttcatca agccagaact ggagcaatta caaaaagaaa ttgctgcaga tgaagcaagc
    16861 ttgggttcag aagaagcggc tttgaagacc ttgcaagacc agatggctac attgacagaa
    16921 agattagaag ccatcaaatc tcaaggagaa caggcacgta ttcaggagca aggcttgtcc
    16981 ctcgcttatc agcaaactag tcagcaagtt gaagaactgg aaactctttg gaaactccaa
    17041 gaagaggaaa aagatcgtct ttctgatgga gattggcaag cagacaagga aaactgccaa
    17101 gagcgtcttg ctgcaatcgc cagtgacaag caaaatctgg aagctgagat tgaagagatt
    17161 aagtctaata aaaatgccat ccaagaacgc tatcaaaact tgcaggaaga gctagcgcaa
    17221 gctcgtttgc ttaagacaga actgcaaggg caaaaacgtt atgaagtggc tgatattgaa
    17281 cgcttaggca aggaattgga caatcttgat tttgaacaag aggaaatcca gcgccttctt
    17341 caagaaaagg ttgacaatct tgagaaggtt gatacagaat tgctcagtca acaggcggaa
    17401 gaatccaaaa ctcagaaaac gaacttccaa caaggtttga ttcgcaaaca gtttgagttg
    17461 gatgatatag aaggtcagct ggatgatatt gctagtcatt tggatcaggc tcgccagcag
    17521 aatgaggagt ggattcgcaa gcaaacacgt gctgaagcca agaaagaaaa ggtcagcgag
    17581 cgcttgcgcc atctacaaag tcaattaaca gaccagtacc agattagcta tactgaagct
    17641 ctagaaaaag cgcatgaatt ggaaaacctc aatctggcag agcaagaagt taaggattta
    17701 gagaaggcta ttcgctcact gggtcctgtc aatatagaag ctattgacca gtacgaagaa
    17761 gttcacagcc gtctggattt cctcaatagc cagcgagatg acattttgtc agcgaaaaat
    17821 ctgcttcttg agactattac agagatgaat gatgaggtca aggaacgctt taaatcaacc
    17881 tttgaagcta tccgtgagtc ctttaaagtg accttcaagc agatgtttgg cggaggtcaa
    17941 gcggacctga ttttgactga gggagacttg ctgacagctg gggttgagat ttctgttcaa
    18001 cctcaaggta agaaaatcca gtcccttaat ctcatgagtg gtggtgaaaa agctctatcg
    18061 gctcttgcct tgctcttctc cattattcgt gtcaagacta ttccatttgt tatcttggat
    18121 gaggtggaag ctgcgctgga tgaagccaat gttaaacgtt ttggggatta cctcaaccgc
    18181 tttgacaagg acagccagtt tatcgtcgta acccaccgta agggaaccat ggcagcggct
    18241 gattccatct atggagtgac catgcaagaa tcgggtgttt caaagattgt ttcagttaag
    18301 ttaaaagatt tagaaagtat tgaaggatga caattaaact agtagcaacg gatatggacg
    18361 gaaccttcct agatgggaat ggacgctttg atatggatcg tctcaagtct ctcttggctt
    18421 cctacaagga aaaagggatt tactttgcgg tggcttcggg tcggggattt ctgtctctgg
    18481 aaaaattatt tgctgatgtt cgtgatgaca ttattttcat cgcggaaaat ggcagtttgg
    18541 tagagtatca aggtcaggac ttgtatgaag cgactatgtc tcgtgacttt tatctggcaa
    18601 cttttgaaaa gctgaaaacg tcaccttatg tagatatcaa taaactgctc ttgacgggta
    18661 agaaggggtc atatgttcta gatacggttg atgagaccta tttgaaagtg agtcagcatt
    18721 ataatgaaaa tatccaaaaa gtagcgagtt tggaagatat cacagatgac attttcaaat
    18781 ttacaaccaa cttcacagaa gaaacgttag aagctggtga agcttgggtc aatgataatg
    18841 tccctggtgt caaggctatg acaactggct ttgaatctat tgatattgtt ctggactatg
    18901 tcgataaggg tgtagctatt gttgaattag ctaaaaaact tggtatcaca atggatcagg
    18961 tcatggcttt tggagacaat cttaatgact tacatatgat gcaggttgtg ggacatcctg
    19021 tagctcctga aaatgcacga cctgaaattt tagaattagc aaagactgtg attggtcacc
    19081 ataaggaacg gtcggttata gcttatatgg agggcttata atggcagata taaaattgat
    19141 tgcattggac ttggacggga ccttgctgac tactgataaa aggctgacgg atcgtaccaa
    19201 gtcaaccttg aaagctgcgc gtgatcgtgg tatcaaggtc gtattgacaa ctggtcgtcc
    19261 cttaaaagcc atggatttct ttctccatga gttagggact gacggtcagg aagatgagta
    19321 taccattact tttaatggtg gattagttca gaaaaataca ggagaaatcc ttgataaaac
    19381 agtcttttca tatgatgatg tggcacgttt gtatgaagaa acagagaaat tatcactgcc
    19441 tcttgatgcc atctcagaag gaacagttta tcaaatccaa tcggaccaag aaagtcttta
    19501 tgccaaattc aatccagctt tgacttttgt tccagttgac tttgaagacc tgtctagtca
    19561 aatgacctac aacaaatgcg tgaccgcctt tgctcaagaa cccttggatg cagccattca
    19621 gaagatttct ctagaattgt ttgaccaata tgaaatcttt aaatcacgtg aaatgttgct
    19681 agaatggtca ccaaagaatg ttcataaagc aacaggtttg gcaaaactaa tcagccatct
    19741 tggaatcgac caaagccaag tgatggcttg tggtgacgag gccaacgacc tctctatgat
    19801 tgaatgggca ggtcttggtg ttgctatgca aaacgctgtt cctgaagtaa aggtagccgc
    19861 aaatgtagtg acgccgatga ccaacgatga ggaagctgtc gcctgggcta tcgaagaata
    19921 tgtgctaaag gagaactaag atatgggatt gtttgaccgt ttattcggaa aaaaagaaga
    19981 acctaaaatc gaagaagttg taaaagaagc tctggaaaat cttgatttgt ctgaagatgt
    20041 tgatcttacc ttcacagaag ctgatgaagt tcctcaggaa gaagcagagg ttgaaattgt
    20101 tgaacaagct gtgttccaag aagaggaaat ccaagacaca gttgaagaaa gtcaggattc
    20161 agagccagct gtaggggttt ctcaagaaga aatagaagaa ttaccaaact cagaagaatt
    20221 accagaggaa gagaagcttg agcacgaagg aactgtagaa gaaaataatt ctgaagtgct
    20281 tgaaccagaa gctcctcaaa cagaagaaac tgttcaggaa aaatatgacc gcagtcttaa
    20341 gaaaactcgc acaggtttcg gtgcccgctt gaatgccttc tttgctaact tccgctctgt
    20401 tgacgaagaa tttttcgagg aactggaaga actgctgatt atgagtgatg ttggtgtcca
    20461 agtcgcttct aacttaacgg aggaactacg ttacgaagcc aagcttgaaa atgccaagaa
    20521 acctgatgta cttcgtcgtg tcatcattga gaaattggtt gagctttatg aaaaggatgg
    20581 tagctacgat gaaagcatcc acttccaaga taacttgaca gttatgctct ttgttggtgt
    20641 gaatggtgtt gggaaaacaa cttctatcgg aaaactagcc caccgctaca aacaagctgg
    20701 taagaaggtc atgctggttg cagcagatac cttccgtgcg ggtgcagtag ctcagctagc
    20761 tgaatggggc cgacgagtag atgttccagt agtaactgga cctgaaaaag ctgatccagc
    20821 cagcgtggtc tttgatggta tggaacgtgc cgtggctgaa ggtatcgata ttctcatgat
    20881 tgatactgct ggtcgtctgc aaaataagga taaccttatg gctgagttgg aaaagattgg
    20941 tcgtattatc aaacgtgttg tgccagaagc accacatgaa accttcttgg cacttgatgc
    21001 atcaacaggt caaaatgccc tagtacaggc caaagaattt tcgaaaatca cacctttaac
    21061 gggaattgtt ttgactaaga ttgatggaac tgctcgagga ggtgtggttc tagccattcg
    21121 tgaagaactc aatattcctg taaaattgat tggttttggt gaaaaaatcg atgatattgg
    21181 agagtttaac tcagaaaact ttatgaaagg tctcttggaa ggcttaatct aatcagaagc
    21241 aaaaatcctg caaggtacaa acttgcagga tttttttatt cgaaacgacc atcttgacga
    21301 taggcgatat ctggttgcca agtccatttg gcaccgaatt tttcaagtag gtcaaagctg
    21361 gcttgaggtc ccatgcttcc agctttatag tcatgaagtg gggcaccatt ttcagcccag
    21421 agcttttcaa tacggtcaat caacttccat gacgcacaaa cttcatccca gtggctaaag
    21481 ttagttgagt tgttatttag gacatcataa atcaattttt cgtatggttc tggagaagca
    21541 ccagttgcag tcgcatctgt acggtaatca agtgagttag gagccaagtt aaattcttct
    21601 cctacttgct tcccatttag gctaagagag aagccttctg ttggttgaat atagatggtc
    21661 aaaatatttg gagcaagtgg ttctccaaag atagaatcca tttgtttaaa gacgatgttg
    21721 acatgagttc ctttttcagt cagtcgttta cctgtacgga aaaagaaagg aacaccacgg
    21781 aatcgatcgc tgtctacaaa gaaggcacca gatgtaaagg tttcagttgt tgattctgga
    21841 ttcacatttg gctcgctacg ataagagatg tatttcatgc catcaatctt accagagcgg
    21901 tattgcccac ggataaagtg ttctttgagt tcttcatcag ttggatgata gaggttttta
    21961 aagaccttaa tcttttcagc acgaatctcg tcttttgtga agcttgctgg tttgtccatg
    22021 gcgaggagcg aaagaagttg tagagtgtgg ttttggacca tgtcacggag ggcaccggat
    22081 tggtcatagt agccaccacg ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca
    22141 ttgtcgataa aatccttgtt ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca
    22201 aagatgcttt ggatcatttc cttaccaaga taatggtcga tacggaaaat ttgttcttcg
    22261 tcaaatgttg ctaggagttc gacattcaac ttgcttgcag ttgcgtaatc tgtaccaaat
    22321 ggtttttcaa cgatcaagcg ctcaaaacct ttgccatcga caatgttttc agatttgagg
    22381 tgtttggcaa tggttccaaa gaactgaggt gccatagaca agaagaagag cttattgtgt
    22441 tcagcttggt atttttcatt aagctcagct tgtaattgac gcaaagcaat ataatgttcc
    22501 gaatcattga catcatggct ttgatagtag aagtggctag caaattcttg ggcttgctcg
    22561 gtactatctg ccaaatcaag gatggactcg acaactacag attcaaaata ttccttactc
    22621 caaggtctac gggcagttcc aataacggca aagtgcttgg aaagattgcc ggattgatat
    22681 agtctaaaaa gggaagggta gagcttgcgt ttagccaggt ctccactcgc accgaaaatt
    22741 gtaacaataa ccttagatga catctagcta cctaatttct atttttattc ctagtcttgc
    22801 taggtatgag gaaacctcat ttcataaact taattctaac ataattttcc gaaaaatcaa
    22861 aaattccaat acgaggtaga aaaactgcaa ggaaatcctt acagtttgag tttagacgtt
    22921 taagacctta tctaagaact ctttcagacg agggtgttgt gggttatcaa agatttggtc
    22981 aggtgttccg tcttcaagga actcgccatc tgcagtaaag ataacgcggt tggcaacctg
    23041 acgagcaaat cccatctcat gggttacgat aatcatggtc atgccttgct cagccaattc
    23101 cttcataacg ttaagtacgt ctccaaccat ctcagggtca agggcagaag ttggttcatc
    23161 gaagagcatg atgtctggat tcattgctag gccacgagcg atggccacac gttgtttttg
    23221 accacctgat aggctatctg gattggcatt agctttatct gctagtccaa ccttttcaag
    23281 caactccatt cccaattcct cagcttcttc cttagtcatc aacttgtgct caataggagc
    23341 aaaggtgatg ttgtccaata cagacatatg agggaagagg ttgaagtgtt ggaataccat
    23401 gccgatattt tcacggacgt ggtcaacatt ggttgttttt tcagttaaat catagccgtt
    23461 cacagtgatg tgaccgctag tgacttcttc taaaagattg aggctacgga ggaaagttga
    23521 cttaccagaa cctgaaggac cgatgataca aacaacatct ccttcataga acttagtcgt
    23581 aattcctttt aggacttcat tttttccata gtacttgtgt aaatcattta catcaatttt
    23641 taattttgcc attaacgaat cctcttttct aagcgtttcg ctagtctagt caaaagtgtg
    23701 ataattacaa gatagaagat agcaaggatt gcatacatct tgaaactttg gtagttacga
    23761 gcaatgataa tcttaccagt ttggaagagt tcaaccaaac cgatagcaga tacgatagtt
    23821 gtatctttaa gagcgataac gaattggttg acaaagtttg gcaacatcaa tttagttgct
    23881 tgtggcaaga taatcttacg catggttttt ccataagaga tacccaagct tcggctggct
    23941 tccatttggc caactggaac ggcctgaata ccaccacgaa cgatttcagc gatataagca
    24001 gccgcattga gtgagagggc aattgttcca gctacaaagt cgttaattgg gctttgttgg
    24061 cctgtgatag actcgatgaa gtttggaatt ccccagaaga tgaaggctgc aagaatcatc
    24121 aatggaatac cacgaataac gtcaacgaaa atctcagaga tgacgcgaag agatttgtat
    24181 gggctaacgc taaacatacc gaagataatt ccgatgacaa tggcaatagc aaatgagata
    24241 agagctagag caagagtgat accaagaccg ctaaggagtt gtttgtagtt gttttgaagc
    24301 aagccccaga gcgttgtttc gtcaacagta cttgttgaag cagttgaaga ttcgctagct
    24361 aggtatttgt caagaatctt ttggaattca ccgtttgctt taaggtttgc aagtccgttg
    24421 ttgaacattt caatcagttc tggatttgct ccttttttaa cggcaaaggc tgtttcaccg
    24481 attggagttc cagagattgg agttttcaat ttttgacctt ggctgataga atatttgaga
    24541 acaggttcat catccataac ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa
    24601 gaaccatcag caaaggtttt gattttgtaa ccgtatttgc tttgattttc tgttaggaag
    24661 gtttgagaag cagttccgtt tttaacaccg actgtctttc cttttagatc ttcataagaa
    24721 gcaatattgc ttgattcttt gacaccaaga atggtattag cagtgtagta tgattctgag
    24781 aagtcaaaag ttgccttacg agcatctgtg acagacatac cagcaatgat accatcggct
    24841 tgaccagctt ggacagcact gatagcagca tcaaaaccag ggttggtgat ttcaatttca
    24901 aaaccttggt ctttagcgat tgccttaatc aattccatat caataccagt gtattggttg
    24961 cttgaatttt ggaaaacaaa aggtgcaaaa gaagaatcgc tggcaatgat atatttagcc
    25021 ttaacaggaa tagcttttaa tcctgcgaga gtagttgtag ttggcactgc tgaagatgat
    25081 gaagcagtcc atttcttgat aattttatca agactaccat cttttttcat ttcagacaag
    25141 gcttggttaa attcagtaac caggtgctcg tatttacttc cttttttcac accgaaagca
    25201 aaacttccta cagcttcacc atccatttca atatggaggt cttgaccttg gttaatggca
    25261 tattcgataa caggtttgtc atccatcatg gcatcgatgg caccagcact caagctgttg
    25321 ttcattaaat caccagtgtc aaatgtttta atagtaaagc cgtatttatc tttgattgtt
    25381 tcaaggaaac gttgagcggc agttccgttt ttaacaccaa cggttttgcc agttaattgg
    25441 tcgtacttgc taattttgtg tgactttgta gtagcaatga caacttttgt atcatagtaa
    25501 gtatcagaca tggtgaagac tttttcacgt tctttagtct ttgtcatccc tgccatgata
    25561 gcgtcggctt gcccagcttg aaccgcattg actgctgcgt caaatccagg ataggacatc
    25621 tgaatgttcc agcctttaat ctcagcgact ttgttaataa tgtcaacatc aattccttta
    25681 taagtttgat ctgaatcttt aaactcaaaa ggtgcatagg cggtatcaga aacaatctta
    25741 atcgtttctg ctttggcaat acctaatgag aaaattggga ataaaattag caaaaatgct
    25801 agaaattttt tcttcatttt tagtctcctt ttccgaatat tctctcatta tatcagaaaa
    25861 agtaaaaaaa ggcaaatttt tatatttttc gtgtcagaaa atataacatt gatttttcct
    25921 tttctttctt gaattgctat taaaaagtgc tataataata gtatatatag aagaaaagag
    25981 gacggggata tgaagaacaa aagaatattt aaagacttcc aagcttcaaa aatgagttta
    26041 aacatttaca caagcccctt gttagccttt gtttttgtct tcataggaga gtttgtggct
    26101 tttactttgt atggtattgg cttgttagct ctcatcggac ttgctagaaa ttttggagag
    26161 gctggtcaaa atcttgcaac ctacttgcag accttgcatc agagcttgac ggataaaaca
    26221 agtgactttc gtttaatttt aggattactg gcctttggtt ttattcttaa cactgtgttc
    26281 aggtggacaa gaaaagttga gaaaagacct attcgaacct tgggatttta tagagagaat
    26341 ttcctcagca atcttctgaa aggatttagt ctaggcttgg cactttttct tctgaccttg
    26401 ttaggtttag tggtcttagg tcaatatcgt ttggaatcca ttcacttgaa tccttattct
    26461 cttgcctttg tcgtctttac tatcccattt tggattttac aggggacagc agaagaagtg
    26521 gtggcccgtg cttggctact tcctcaattg gcctcaagaa ccaatctaaa actagctatt
    26581 cttatatcta gcctgttctt taccctgctt catatgggca attctggcct cacccctcta
    26641 tctctagtaa atctcttttt attcggagtt gccatggctc tttatcttct caaaactgat
    26701 acagtttggg gtgttgcagg tattcatggt gcttggaatt ttgctcaggg taatctcttt
    26761 gggattttag ttagtggtca accgtcagga acgtctctga tgaccttttt accacaaggc
    26821 aatcaagatt ggctatcagg tggttctttt ggcatagaag gttccattat gacaagtctg
    26881 gtattactac tgctgattgt ctatcttgct aataaattaa agaaagaaaa tgaaaggatg
    26941 tgacttcggt ccgtcctttt cttcgtgaaa atactataag tatgctaaaa taggaatagc
    27001 acatggagag aggattctta tgatcaatca cattacagat aatcaattta aactagtatc
    27061 aaaatatcaa ccatcaggag atcaacccca agctatcgag cagttggtgg ataacattga
    27121 ggggggagaa aaagctcaga ttctgatggg ggcgactgga acagggaaga cctatactat
    27181 gagtcaggtc atttctaaag tcaataaacc aactctggtt attgcccaca ataaaactct
    27241 ggctggtcag ctctatgggg agtttaagga atttttccct gaaaatgcag ttgagtattt
    27301 cgtatcctac tatgattatt accagccaga ggcctatgtc ccttctagcg atacctatat
    27361 tgagaaggat agttctgtca atgacgagat tgacaagctt cgccactcag ctacctcagc
    27421 ccttttggag cgtaatgatg ttattgtcgt ggcctcagtc tcttgtatct atggtttggg
    27481 ttcgcccaag gaatacgctg atagtgtcgt tagtctccgt cctggtctag agatttctcg
    27541 tgataaactc ttgaatgact tggtcgatat tcagtttgaa cgtaatgata ttgatttcca
    27601 acgcggaaga tttcgcgttc gtggggatgt ggtagagatt ttcccagctt cccgagatga
    27661 acatgccttt cgagtagaat tttttggaga cgaaattgac cgtatccgtg aggttgaggc
    27721 tctgacaggt caggtattgg gagaggtgga tcatttggcg attttcccag ctactcactt
    27781 tgtgaccaat gacgaccata tggaagttgc cgttgccaag attcaagcag aattagaaga
    27841 gcagttagct gtctttgaaa aggaaggtaa actgcttgaa gcccagcgtt tgaaacagcg
    27901 gacagagtat gatatcgaaa tgttgcgtga gatgggctat accaatgggg ttgaaaatta
    27961 ttctcgccac atggatggac ggagcgaagg agagcctcct tatacgcttc tcgacttctt
    28021 cccagatgat ttcttgatta tgattgacga gagtcatatg accatagggc aaatcaaggg
    28081 catgtacaat ggagaccgtt cgcgtaagga aatgctagta aattatggtt tccgtttacc
    28141 gtctgccttg gacaatcgtc ctctccgtcg tgaggagttt gaaagccatg tgcatcagat
    28201 tgtttacgta tcagcgacac ctggtgacta tgaaaatgaa cagactgaga cggtgattga
    28261 gcaaatcatt cgaccgacag ggcttttgga tcctgaggtg gaagtccgtc cgactatggg
    28321 acagattgat gatctcttag gtgaaatcaa tgcccgtgtt gaaaagaatg aacgaacctt
    28381 tatcaccacc ttgaccaaga aaatggcaga ggacttgacc gactatttca aggaaatggg
    28441 catcaaggtc aagtacatgc actcggatat caagaccttg gaacggacgg agattatccg
    28501 tgatctccgc ttgggtgtct ttgatgtctt ggttggaatc aatctccttc gtgaagggat
    28561 tgacgttcct gaggttagct tggttgccat tctcgatgct gacaaggaag gtttccttcg
    28621 taacgagcgt ggactcatcc agaccattgg gcgtgccgcc cgtaacagtg aaggtcatgt
    28681 catcatgtat gcagatacgg ttacccagtc tatgcaacgt gctatcgatg aaactgcccg
    28741 ccgtcggaaa attcagatgg cctataatga agagcatggt atcgtaccac agacaatcaa
    28801 gaaagaaatc cgtgacctga ttgccgtgac caaggcagtt gctaaggaag aggacaagga
    28861 agtcgacatc aatagcctca acaaacaaga gcgcaaagaa ctcgtcaaga aactagaaaa
    28921 acaaatgcaa gaagccgtcg aagtgcttga ctttgaactg gcggctcaga tccgtgatat
    28981 gatgttggaa gtcaaggcct tggattaggg gaatagtatg atttatttaa gaaagttaaa
    29041 gaaagaagat ttgatgtctt tatgggaaat ggcttattca cagcttaatc cagtttggaa
    29101 acagtatgat gctccctatt atgatgatta tcagtatttt tcaaatttta aagaattcga
    29161 actacaaaaa tcagaatcca ttttaagcaa ctcaaatcgc cttggtattt ttgttgatga
    29221 taaactagtt gggactgttt cgcgttattg ggtatgtaaa gaaacaagat ggatggaatt
    29281 gggaattggt atttatgata aaaaattctg gaacactggt attgggaaag ttgctatgtt
    29341 gcagtggata gataggacgt ttcaggatta cttggagttg gagcatctgg gtttgacaac
    29401 ttggtcaggg aatcttggta tgatgaaact tgctgaaaaa ttaagaatga aaaaagaagc
    29461 tcatattcca aaagttcgtt attatcaagg taaatatttt gatagtatta aatatggtat
    29521 tttgagagaa ggctgggaga aaataaatga cggttattat caaatcaatg gaaactcctg
    29581 aagagataga aggtaaatcc ctcgttcact ggcaaacgtg gagagaggct tatgatgacc
    29641 ttttgcctgc agaatttcag gagacaatga cattagaaag atgtcgattc tttagtcaaa
    29701 agtatccaga aaatacattg attgcgatag gtgatctgaa ggtagttggt tttatcagtt
    29761 atggtaactt tcgtgatgat actattcaag ctggtggaat tattgcttta tatgttttaa
    29821 aagactatta cggaaaaggc atagcacaaa agttaatgaa agcagctttg actgctctta
    29881 atcatttttc tgaaattttc ttatgggtat tgaaagataa caagcgcgcc attgctttct
    29941 atcaaaaaat gggttttact tttgatggac aagaaaaaat acttgaactt ggaaagccta
    30001 taaaggaaaa acgaatggtg ttctattcta aataatttta aaaaagtaaa agataatatc
    30061 tctggtagta agtctgaaaa tttaataaat tagaaagcga gtaaatttat gtcccgttcc
    30121 caattaacaa ttttaacaaa tatctgtctg attgaagacc tcgaaacgca gcgcgtggtg
    30181 atgcagtatc gcgcccctga aaacaatcgc tggtctggtt atgcctttcc tggaggtcat
    30241 gtagaaaatg atgaggcttt tgcggagtct gtcattcgtg aaatctacga agaaacaggg
    30301 ttgactatcc aaaatcctca acttgtcggc attaaaaatt ggccactaga tacaggtggg
    30361 cgctatattg tcatttgtta taaggcgact gagttctctg gtacccttca atcttcagaa
    30421 gagggagaag tttcttgggt gcaaaaagac cagattccaa acttaaatct ggcctatgat
    30481 atgctaccat tgatggaaat gatggaagct cccgacaagt cagagttttt ctaccctcgc
    30541 cgtacagaag acgattggga aaagaaaatc ttctagtctt ttactaaata acctagctga
    30601 tccaaggcct cctcgatata gtggaggtct tgttgtgttt cggcttcgac taggtggtaa
    30661 tggatgccat ctgtcaattc agatagaggt ctaaagtcag aatgctcgac ttgttctaga
    30721 aaatgttgca catctctgcg acaagacagt ttaagcaagg tttcaatttc tccataaacg
    30781 ggatggtcaa tcaaggtatt ctggacatgc ccaccattat cgacaatagc aaggagttcc
    30841 tgaccgattt cttcaacttc atgtttcact ttgaaaagtt tgtgaacata aggattggta
    30901 tcaatttgct tatagatgta gccacgattg gtggatagga taggagcgcc atcggctctc
    30961 aaaattgcaa tgtcctgcac aatgacctga cgtgtgacat gaaaatgttc cgccaaactt
    31021 tggccattaa gggctttagg agcttctttc aagagttgga gcagggcttg tttgcgatct
    31081 tttgtcatag cttttccttt taacggcgtt ttcgaagcac tttatagaca gctagtgcta
    31141 atgtatagtc taccatacta tggataattg tgccaaatcc aactagtaca aatagaacat
    31201 agaacatgtt ttctacattg gtacccgaag ttgcgtaaaa aaggacacag gctaatactt
    31261 cagcaagggc atgaacaaca gccaaaacaa aattgaaaac ccaggaagat tttggtttat
    31321 ctagggtatc ggggaatttt tgtaggtaaa gagctcctaa agcaccaaaa gatatatggg
    31381 aaaaagcccg aaaaacgata accatgggat agccagccat caaaaatcca aaactagagg
    31441 ctaggatgac aaaaactgcc atcaagggcg acaagaacat ggctataaaa atagcgatgt
    31501 ggctccccaa agtataggaa gcaggtggaa tgacaatctt gaaaggcata acaattggaa
    31561 tcaaaatcgc aatagccgtt aaaagggctg tcattgtcat aaattgtgtc tttttccgtg
    31621 tattcacaag aatctccttt ttaactgcat atacactagt atggtacaat aaaccagaca
    31681 ataaagcaag aatttacttg ggtttataga tcatttttta gttaaaagtt atagtagatt
    31741 gaaact
//
LOCUS       DAVBOM010000023        31439 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBOM010000023 DAVBOM010000000
VERSION     DAVBOM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.023"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..108
                     /locus_tag="VQ878_001115"
     CDS             <1..108
                     /locus_tag="VQ878_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3095461.1"
                     /translation="TNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            108..869
                     /locus_tag="VQ878_001116"
     CDS             108..869
                     /locus_tag="VQ878_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3095462.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            897..2054
                     /locus_tag="VQ878_001117"
     CDS             897..2054
                     /locus_tag="VQ878_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095463.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISKKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            2873..3232
                     /locus_tag="VQ878_001118"
     CDS             2873..3232
                     /locus_tag="VQ878_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095464.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIVE
                     VNQAQPLSREFCEKYMG"
     gene            3308..3606
                     /locus_tag="VQ878_001119"
                     /pseudo
     CDS             3308..3606
                     /locus_tag="VQ878_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480038.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
     gene            3593..5457
                     /locus_tag="VQ878_001120"
                     /pseudo
     CDS             3593..5457
                     /locus_tag="VQ878_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5502..6354)
                     /locus_tag="VQ878_001121"
                     /pseudo
     CDS             complement(5502..6354)
                     /locus_tag="VQ878_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            6436..6507
                     /locus_tag="VQ878_001122"
     CDS             6436..6507
                     /locus_tag="VQ878_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET3095465.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            6611..7480
                     /locus_tag="VQ878_001123"
     CDS             6611..7480
                     /locus_tag="VQ878_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HET3095466.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            7467..8189
                     /locus_tag="VQ878_001124"
     CDS             7467..8189
                     /locus_tag="VQ878_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3095467.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            8186..8716
                     /locus_tag="VQ878_001125"
     CDS             8186..8716
                     /locus_tag="VQ878_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095468.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            8720..9814
                     /locus_tag="VQ878_001126"
     CDS             8720..9814
                     /locus_tag="VQ878_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095469.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            9817..10488
                     /locus_tag="VQ878_001127"
     CDS             9817..10488
                     /locus_tag="VQ878_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095470.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDVELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            10490..11518
                     /gene="galE"
                     /locus_tag="VQ878_001128"
     CDS             10490..11518
                     /gene="galE"
                     /locus_tag="VQ878_001128"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3095471.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLADGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            11542..12786
                     /locus_tag="VQ878_001129"
     CDS             11542..12786
                     /locus_tag="VQ878_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HET3095472.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVGSITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQVLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMFVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            12836..13195
                     /locus_tag="VQ878_001130"
     CDS             12836..13195
                     /locus_tag="VQ878_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3095473.1"
                     /translation="MISRIGDIMFDFANNTFLAGLNPTSLSVVAIYQSLESMIGVLFN
                     LFGGVIADSFKRKKIIITTNILCGIACITLSFISQEKWLVYAIVITNVILAFMSAFSG
                     PSYKAFTKEIVKKDSIS"
     gene            13247..13999
                     /locus_tag="VQ878_001131"
     CDS             13247..13999
                     /locus_tag="VQ878_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3095474.1"
                     /translation="MIAIFLYKLLGIHGVLLLDGLSFLIAASLIFFITPVNEEVDTKE
                     NMTIRGIFDDLKIGFTYVYSHKQILTIIALSALVNFFLAAYNLLLPYSNQMFGSISSG
                     LYGTFLTAEAIGGFIGAILSGFINKSLSSKRLMLFLAYSGLMLMLTAPIYYMFRNVII
                     LAFTPALFSLFLSIFNIQFFSIVQRDVDNEFLGRVFGIIFTVAILFMPLGTVFFSVVL
                     NPNNTFNFFIIGVSITILSLIFSTLLKRYDRS"
     gene            14679..14900
                     /locus_tag="VQ878_001132"
     CDS             14679..14900
                     /locus_tag="VQ878_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095475.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            15348..15650
                     /locus_tag="VQ878_001133"
                     /pseudo
     CDS             15348..15650
                     /locus_tag="VQ878_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            15806..17035
                     /locus_tag="VQ878_001134"
     CDS             15806..17035
                     /locus_tag="VQ878_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3095476.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            17055..19751
                     /gene="ppc"
                     /locus_tag="VQ878_001135"
     CDS             17055..19751
                     /gene="ppc"
                     /locus_tag="VQ878_001135"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET3095477.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    19834..20051
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20164..21168
                     /locus_tag="VQ878_001136"
     CDS             20164..21168
                     /locus_tag="VQ878_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3095478.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            21237..22103
                     /locus_tag="VQ878_001137"
     CDS             21237..22103
                     /locus_tag="VQ878_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095479.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            22100..22858
                     /locus_tag="VQ878_001138"
     CDS             22100..22858
                     /locus_tag="VQ878_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095480.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            22948..24708
                     /gene="dnaG"
                     /locus_tag="VQ878_001139"
     CDS             22948..24708
                     /gene="dnaG"
                     /locus_tag="VQ878_001139"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET3095481.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKIIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            24711..25820
                     /gene="rpoD"
                     /locus_tag="VQ878_001140"
     CDS             24711..25820
                     /gene="rpoD"
                     /locus_tag="VQ878_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET3095482.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            25834..26163
                     /locus_tag="VQ878_001141"
     CDS             25834..26163
                     /locus_tag="VQ878_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3095483.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            26278..27321
                     /gene="cpoA"
                     /locus_tag="VQ878_001142"
     CDS             26278..27321
                     /gene="cpoA"
                     /locus_tag="VQ878_001142"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET3095484.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPATLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            27337..28662
                     /locus_tag="VQ878_001143"
     CDS             27337..28662
                     /locus_tag="VQ878_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3095485.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAISEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            28693..28869
                     /locus_tag="VQ878_001144"
     CDS             28693..28869
                     /locus_tag="VQ878_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3095486.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            28928..29062
                     /locus_tag="VQ878_001145"
     CDS             28928..29062
                     /locus_tag="VQ878_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET3095487.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            29126..30436
                     /gene="obgE"
                     /locus_tag="VQ878_001146"
     CDS             29126..30436
                     /gene="obgE"
                     /locus_tag="VQ878_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET3095488.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEETYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            30446..30604
                     /locus_tag="VQ878_001147"
     CDS             30446..30604
                     /locus_tag="VQ878_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095489.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT        10502 a         4775 c         6357 g         9805 t
ORIGIN      
        1 acaaatatct atttagtaga aaattttgat gaaatagaga gatatagcgg ctatttggat
       61 ggaattgaac gtatgttaga gatatctgaa aaacggatgg tagcctagtg gaaatccaag
      121 attatactga cagtgaattc aaacatgctc tagcacggaa tcttcgttca ctgacaagag
      181 gaaaaaagtc cagtaagcaa cctatagcga ttttgctcgg agggcaaagt ggtgccggta
      241 agactacaat tcatcgtatt aaacagaaag aatttcaagg aaatattgtt atcatagatg
      301 gagatagttt tcgttctcag catccacact atttagaact gcagcaagaa tatggcaaag
      361 atagtgtaga atacaccaaa gattttgcag gtaaaatggt agagtcttta gtaacagaat
      421 tgagtcattt gggatacaat cttttgatag agggaacttt acgaacagtt gatgttccaa
      481 agaaaacagc acaactcttg aaaaataagg gatatgaagt acaattagcc ttgattgcga
      541 caaagcctaa gctgtcctat ctgagcactc ttattcgata cgaagaactg tacgctatca
      601 atccaaatca agcacgcgca acaccaaaag aacatcatga tttcattgta aatcatctag
      661 ttgataatac acgacaattg gaagaactag ctatttttga aagaattcaa atttaccaac
      721 gagatagaag ttgtgtatat gattcaaaag aaaatacaac ttcagcagca gatgttcttc
      781 atgagttatt gtttggagag tggagtcagg tagaaaagga gatgttgagg gtaggggaaa
      841 agagacttaa tgaattactt gaaaaataaa caattgatat ttttaggaga gtagaaatga
      901 gagggtttaa taacaagata aagtctgttt atcaagaact aacaaattcc aaagagaaat
      961 tcggtagctt tcacaagact ttaattcatt tgcatacacc tgtttcttat gattacaagc
     1021 tattttctaa ttggactgca acgaaatata gaaaaattac tgaagatgaa ctatatgata
     1081 tattttttga aaataagaaa ataaaagttg ataagacaat tttttttagt aattttgata
     1141 aggttgtttt ttctagttca aaagaatata ttagttttct tatgttagca gaggcaatca
     1201 taaaaaatgg aatagaaata gttgtagtaa ctgatcataa tactaccaaa ggtattaaaa
     1261 agttacaaat ggcagtctca atcataatga aaaattatcc gatttatgat atacatcctc
     1321 atattttaca tggagtagaa attagtgcag cagataaatt gcatattgta tgtatatatg
     1381 attatgaaca agaatcatgg gttaatcaat ggttaagtga aaatattata agtaagaaag
     1441 atggaagtta tcaacattca ctgactataa tgaaggattt caataatcaa aaaatagtta
     1501 actatattgc tcatttcaat agttatgaca ttttgaaaaa aggttctcac ttatcaggtg
     1561 catataaacg aaaaattttt tctaaagaaa atacacgatt tttggagttt aatattaact
     1621 cgaaagaatc ttcgcaacaa cttgatattc tctataaaga agttggtgta ttaagtttgg
     1681 gacaaaaagt tgtagccatg cttgattttt tattagcata tagtgactat tctaaagact
     1741 tcagaccatt gattattgat cagcctgaag acaatctaga caatcgttat atttacaggc
     1801 atttagttca gcagtttaga gatgtgaaag ctcaacgtca aattatttta gcaacacata
     1861 atgctacaat tgtaacaaat tctatgacag atcaagttgt tattatggag tcagatggag
     1921 ttaacggatg gattgaatca cagggatatg ttagtgaaaa atatataaaa aatcatatca
     1981 tcaatcaatt agagggagga aaagattcct tcaagcataa aatgtctata tatgagacgg
     2041 ctttatcaga gtagagtcag aaaaagtagg ttagaaattt agcctacttt tttctttgtt
     2101 cgacaggcat agtgtacatc tgaggtccaa gtcctctgtg gatatttgct gcagatgaaa
     2161 ccaatagcga ctcctaagcc tgaatatcgt gatgtagggg ggataggaag gaattagcga
     2221 aatcaaggtt ctacaaacag aatcgtgact tgaagccata tatagcggat gaggaactct
     2281 aaaatccaaa taggtgtcgt aacctatata cgtaaattac gagagtaaac taggaaagat
     2341 gtacggctta ttccgtgagc gtttaggacg tagtacaacg aatcatggga gtcagctgaa
     2401 cacatagtat tgaagaaatt tctgtaatgg aaatggagcg aagaagtgaa caattaaatg
     2461 aatacctctc taattaaatt tgtcaattct aattcctggt atgaaaagac agtgacctaa
     2521 aaatgtaaac gatgggagct gatcataaat ataggacggt acatgcagtg gtgttagaga
     2581 ttagtcccta cttgatttgt gataacttcc ccaactttct tctgctatac ttttctcaac
     2641 ttttaaaaat ccaactaaga attttacctg ggagtttggg ggcgtagcca ccaagttatc
     2701 ttatggttag ctgtcaaaac tggaaggttt tggttagctg gcgatatgat tttttgggta
     2761 ttgtgaccac aatgcctgag ctcgcaaaga ccgaacaagg actttaagaa atttcccgta
     2821 tgacacacgg ggtcggggtt tacccgagaa aggatgaaag tgaggaaaag agatgtctga
     2881 acagtaccgt gacattcgaa aagaggtaaa tctaaccgca gatgagctaa aacagattga
     2941 aaaaatgatg gaggttgata attatcgtca cttttcacca ttcgtcaggg ataaaatttt
     3001 gatgactgat gacaaacagt tagctgccaa agaatggttt tccctttggc agtctcaaaa
     3061 gtttgaacag atcagtcgag atgtgcattt ggttttgatt atcgcaagag agaatcatca
     3121 agtgactcaa gagcacgtct caatcttatt gacttgtgtt caagaattaa ttgtagaagt
     3181 caatcaagct cagccactca gtcgtgaatt ctgtgaaaaa tatatgggat aggagactgc
     3241 tatggtttat cgttatcgta ctaatctaaa aaaatatttc taactgattc agaattgaat
     3301 taattaaatg atcgtattac taagagtcac tgtcaaaatt tctcagtcta cgccagaaaa
     3361 gttttgctta atcccaatat gtcatttgtc acgattaaca ctgatactta tgaacagtta
     3421 gtgtttgaat tgaggaggat tggaaataac atcaatcaaa ttgcgcgtgc gattaatcaa
     3481 agccatctga tttctcagga ccaattacaa gaattgagta aaggagtcgg agagttaatt
     3541 aaggaagtgg acaaagaatt tcaagtggag gtgaaaagac tgaaggagtt tcatggtagt
     3601 tactaaatac tttgcgacgc acggaaaaaa atatcgtagg cgtttgatta aatatatcct
     3661 caatccagat aaaacagata atctaaaatt agtatctgat tttggcatga gtaattactt
     3721 agattttcct agccatgcag aaatggtaga aatgtacaat gttaacttta ctaataacga
     3781 caagttgtac gagtccagaa atgaccgaca agaaaaacac caacaaacta ttcatgccca
     3841 tcatctcatc caatcatttt ctcctgaaga taatctgaca cctgaagaaa ttaaccgcat
     3901 tggttatgag accatgatgg aattgacagg aggtcgtttt aagtttatcg tagcaactca
     3961 cacagacaaa gatcatgttc ataatcacat cctaattaac gctattgacc gcaattcaga
     4021 taaaaagttg atatggaact atgccttgga acgaaacctc cgtatgattt cagaccgtat
     4081 ttctaaaatg gctggtgcaa aaattattga gaaacgttat tcctatcgag attataaaaa
     4141 atataaggaa tctagtcata aatttgaatt gaaacaacgt ctttattttt tgcttcagca
     4201 atctaaatcg tttgatgatt ttttagagaa agcaaagcag ttgcatgttc agattgattt
     4261 tagtcaaaag catagccgtt ttttgatgac agatagaacg atgataaaac caattcgagg
     4321 tcgccaactt agtaaacgag atttatatga tgaagacttt tttaaaacat attttgccaa
     4381 acaagagatt gaaagtcatt tagaattttt gttgaaccgt gtcaattctt tagaagagtt
     4441 aataacaaaa gcaaaagaat tgaatctaac cattgactta aaacaaaaaa atgtaacttt
     4501 tatcctggaa gaagataatc aaaagataag tttgggtcat aaaaaataag tgataagaaa
     4561 ttatatgatg tcaaattttt tcaagattat tttaaaaata aggaagtcgt tgcttcagaa
     4621 ggattagaga atttatagga acagtaccat gctttccaag aagaacgaga taaggataaa
     4681 gtatccactg aagagattga ggaagccttt gagatattta aggaaaagag agatgctgtt
     4741 cgtgaatttg aagtggaact tgcagagaac caaatagaga agctagttga tgagggaatt
     4801 tatatcaaag tgtcttttgg tattaagcag agtggtctta ttttcattcc caattatcaa
     4861 ttggatacta tggaagaaga caatcagaaa aaatataaag tctacattcg agaaacgtct
     4921 tcttactttg tctataataa agaaaacatg gataataatt gtttcatcaa gggtaggacc
     4981 ttaatcagac aattgagcaa cgatagccaa aaactcccct atagacgacc aactttaaaa
     5041 agtcttcaag agaagatttc taaaattaat cttatgattg aactatctaa cacgaacaaa
     5101 caataccaag aaatcaaaga tgagcttgta ttagaaattg cagagattga tatgcagcta
     5161 gaagaaaccc aagaaaaaat cgccacctta aacaagatgg cggaagtcct tatcaatttg
     5221 aagagtgaag atcatgagac tagaaaatta gctaagtatg attttgacca aatgaacatg
     5281 acggaatcaa taatgttaga tcgactcaat acggatattt taaaattaca acaggaactt
     5341 ggtaatgaaa ttaataaata tgaggagata gctagaagat tggatttgtt tgtgaaaatt
     5401 attaatacca ataaatttac agttctaaaa tttcacgaga atgccttact agaataatat
     5461 tatttacgac taattagtta aaagatagag aataatttca tttatttttt atttactagt
     5521 ttattaaaat ggtcagtata gtgtaatttt aacttgtatt ctcctaaaat atcgagaact
     5581 tgtatagctt gtttcattgt ttcaatacca ctacttaatt gacgtttaaa ttcatagtaa
     5641 ccggttgcat agagaaaaac tgtctgttca taaaagttta attcattctc taacaatccc
     5701 tttatctcat taattaaata agagcaatta gaaaattctt ctttatctat gctgagaatg
     5761 aaacaattta tagctagctg agtgacaatc cgcttatttg ttttatttag agatgagtaa
     5821 atataattat ttaacatttc tttagttaag taagaagtag gagttgtagt taattgttcg
     5881 tacacagtta cctaataaaa taatctcata ataaccccat ttttcaactt taaagagata
     5941 atctgctagt tgaagtaatt catcatctga tggaatgatt cttgaatcca ttgtgtgtaa
     6001 aatggatttt accattgttt tttcaaaaga atctaaagtg taatttgagg aatccgaaag
     6061 tagagattgt atattattga tgttttgtaa tgaatattgt ttacggatat actgtattaa
     6121 gttggcaaat gactcagttt ttgtatagtc ttcatcgtgt aaaataagaa actcatccaa
     6181 agtaatgtgt aatttgtcta aaatattgat cagtcggata catgatatct ctgactctcc
     6241 acgttcaaat cgggatattt gcgattttga aagatgctca tcagcaacag agcatagact
     6301 gatttgtttg cctttacgaa cttttctaag tgtgatgcca agttttgatt tcatagtttt
     6361 tcccattttc ccaacaaaaa gttaacttag ttttatttat tgtacaataa ataaaaattg
     6421 aaaggaagtc taaatatgaa gaaaatttca aaatttttcc caattttgat gctagtgatg
     6481 gacattatca ttattgttgg tggttaaatc acttaggtgt acacctaagt ctttagagta
     6541 tctaaagact atacttacta gctaaaacat atttaagtta aatcgtaaaa ttttagagag
     6601 tggtgagact ttgaaacata aaaaagtatt aattataggg tatggtataa tgactcgggg
     6661 tatattaaaa atcctgaaac agtcgaaaaa atataatata tacctatata gtaggcatct
     6721 aaattcaaca ataaatggaa taatatttat tagagaagat gaattacctg atgctataaa
     6781 tcaggttgat tttataatca cttgttttag taatcatatt gaaacggata atttcattaa
     6841 tgagttttta ttaaatatac aatcacttcg taaaaccata gtaattgatt ttacaacctc
     6901 caggattgat tgcgttgaaa aatttaaaaa aactgttgaa attaaagggg gatactatat
     6961 agaggctcct ttcacaggag gtaagttagg aagtaatagt ggtcaactat caattttttt
     7021 acatattgat gaaggtgtaa actataataa aaaggagtta atggaattat taaaattaat
     7081 ttcaaaaaaa atatactttt ttgaaaagag tacggaacca acaaaattca agttaattta
     7141 taactcgtgg ggagcgtatt tgctttactc tattaagcta ttcaaccctt tacagtatga
     7201 tttttcacca aagtctctag aggtagcgaa tacaatcgta tgtaatgatg gttggatgag
     7261 tttagtatgc aactccaaat tagaacagat caatgatcaa gattttgatg acatacactt
     7321 tagagtagaa tatatggtaa aagatttaga atatgctaat ttttcagtct ttcatgatga
     7381 agtgaaagaa ataaattatt tattacagca atatagggat tgcttagtaa ctgatagtgg
     7441 aaaagattat acggtaatag gaaagtatga taacttatag gaatgacttg ctgtctaaag
     7501 aattagatat actaatttca ttttttaaaa aatgcgaggt aggaaaaatt tcactcgtta
     7561 ttactggttc cttggcaaga ggtaatccaa gaatcaagga tgggaaatta gaatcggata
     7621 ttgatattct agttatagta gacagtattc agcaattaat tagtataaaa aagactttag
     7681 agggaaggtt tcactttgta cataaaattt ctttgatttt ttgtttgaag gaaagaataa
     7741 atcgaagtcg ttatcgtgga attattaata gtattagaag tgtagataat cttttagtag
     7801 ataatctgca tataaaaaat caaataatag aagctttaga ctcacctacc aatattgtgg
     7861 agcagactcg ctctatgatt caggaatttt gttattattc atcaaaatat ttaatttcaa
     7921 agaataatta tttggaatta aaactagaaa agtattggaa ggagattgca acattaaatc
     7981 atatcgataa aaagataaaa cacctagatt ttgaaagaat atttgctgtt ttaaaagaac
     8041 acaaaataca aattttggat tcaagtgaat attttttcca aaatgtaaaa acttctgaga
     8101 atatttattt agagatgagg gatttagtat ctttggaaaa tcaaggatta gactttgaac
     8161 attgtatttt gagcttgggg gaaagatgat aataaataca ttaggaccaa ctgcaacaga
     8221 ttgtttttat gcaataaatc gtataaaatt aaaagtagat gtgattgtac tgtatgatag
     8281 ttttgatagt atagttaatt gctttgataa attaaaaggg caatatatat tattacctgt
     8341 agctttcgag agtagtatta aaaattatag ttggaaagat ttcaactttg aatatcataa
     8401 gcggattgaa attgtggatt cttttcactc ttttactaag ggaatggttc taatcgagaa
     8461 ttgtaattat aaaattaata gggcgattat ccaacctgca actgagattt tgatgttaaa
     8521 ctatttaaag aaaaaaagta tggatctgag gatagatttt acccatagta aagttatggc
     8581 aaataaaaaa tttctggaag aaggttatcg tttttcaata gtaagccaag aaacgataat
     8641 taataatgat gatattatta tttgtgaaac tttctctcca gaaatgattt ggtgcttata
     8701 tagagtgaaa ggatagaaaa tgttttctga aattattaag aaatatgata ttgttacact
     8761 gaaagatagt ggttttttga gaggtgattg gttcataggt tcagcgttaa tggctcatga
     8821 ctatgaaagc cttaaggaag ggatatattt ctatccccag gaaacaattt ggacaagaat
     8881 cttggattta gaatatataa atccgtattg ggaaatatat aatcaaactt ataatttctt
     8941 attagttaat aaacaagatt cattagcaat gaatttttta actagtcttc taagagaaat
     9001 agaagttatt tcgtctaaaa cattagattt tgttgttatt acttcaaacg aacacctaat
     9061 taggaattta attgatagag actattatat tattacaaaa gagattccat tttttattga
     9121 aaactcaaaa gttggaaatt attttaaaat ttttgtgaaa aatggaggac agtttattcc
     9181 tataattgac tgtacggaat ttaagattca gtctaagaaa tattttgaga taaatattaa
     9241 taaattctac ctgaaacttt tggattactt tcttcatgga gagattccag aaaaatttaa
     9301 attttttgga aatacctcta atttcaatat agaaagcttg tttctagaat ttattgatag
     9361 ccaagaaaat attcgagtag tttccttgtt ggattgtctt attcaattat cctctaaaaa
     9421 tattgaaatt tcaggaaatt ataaagggca cacagtgaaa aaaatactaa aaaaattcgc
     9481 tttatactca gtaattacca aacttgatat aacgaaagta aatcatttat tgagaaatga
     9541 ttatatctac tttttaatga aggaaattga caatattact aaaaaatatc caaagttaat
     9601 tcaaaagtac cctagagata tcttgagtga taggtatgga ataacaaatg aagtatatag
     9661 atacttaatc ggagagaatt tacatataaa aattaatcat aaattagatg aggttagata
     9721 ttttacagat attccattta ttgatacttc actttctatt gaagagtttg acaaaatagt
     9781 ttctaaaata ttaaaaatta aagtgggagg gtaactatga taagattacc aaataaattt
     9841 aaaggtaata atataactct agaagttaaa ctaaataaag cagttgatgc tagtgtatta
     9901 tacccagatg ttaagtctct agatcaagaa ttgtatcgac aactacaatc agtagaatca
     9961 ttctatctta ccttttctga tatgtattca gaaattaatg aaaataatga aatcttatat
    10021 acagaaataa tctttaagat acctctttgt attggagaag attattttaa ttttccggtt
    10081 gtatcatatg tttcaaatcc ctattcgtta ataagaggat tttatctagg ttttcataag
    10141 gaattggact gtaactatgt atttgatgat gtagagcttc atttttttag ggaagggatt
    10201 tgtgaattta acttcgaatt taaaaatcaa aattcaatca ttacagcaga attaccaagg
    10261 gagtataact atcccttgat cttgtttaat aattccaatc tggttaatca atatggaaaa
    10321 tatactttgt tagacataga caaatataaa ttagagtcta gaaagatttt tgaatttcca
    10381 gaaatttcta tcggtaactt tcttggaagt gaagcaaaat caaatagggt aatttttagc
    10441 caagataaat ttcaaattaa tggcataaag aatatggagg taaattagca tgaaatcatt
    10501 attaataaca ggtggagcag gatacatagg atcacatacg gttttggact tgttagataa
    10561 taattatgaa gtaacaatca ttgatgattt gagtaactct aagaaaaaag ttattgagtc
    10621 tattaagcag atatccaaga agagtagaaa tcttcatttt tataaaattg atttaaaaaa
    10681 tgaagaaaaa ttggaaaatg tttttaagag acataatttt gatggagtaa ttcattttgc
    10741 agggtataaa gctgttggag aatccgtggt tgaaccattg aagtattatg aaaataattt
    10801 attatcaact ataaatattt taaaactaat gaaaaaatat aaggtattta attttgtgtt
    10861 tagttcatca gctactgtat acgaaagtac tcctatcatg ccattctatg agactaatcc
    10921 attaaaagct tcaaacccgt atgggagaac aaaacagtat atagaagtac ttttaaatga
    10981 tttgtttatt tcgaattcaa attggaaaat tgtttgtctg aggtatttta atccattggg
    11041 tgcacatgaa agtggtgatt taggagagga tccaaatgga attccgaata atcttgttcc
    11101 ttacattaca caagttgcaa ttggaaaatt accatattta aatatattcg gagttgatta
    11161 cagtactcct gatgggactt gtataaggga ctatgttcac gttaacgatt tagcagacgg
    11221 acacagaaaa gcattagagt atatttttaa tacagatgaa ggtttatatg aagtaatcaa
    11281 tttaggaagt ggtgttggtt ttagtgtatt tgaaatccta cacagcttag agagtgtcat
    11341 aggctcgtat attccatata agataacttc aaggagagca ggagatatgg acgtttcaat
    11401 tgcagatatt tcaaaagcag aagagctact gggatggaag ccaaggtatg atattatgaa
    11461 aatgtgccaa gatacgtgga aatggcaaca gaaacatcca aatggatatg atgactaata
    11521 attgaaagga ttgggattaa catgcatata gtattattta gatattctgc acgggttgtt
    11581 aaactaaaat atctgtataa cagaaatgta gtaattattg cacctgaggt tcaaagaaaa
    11641 aaatatgaag attatctagc tgaaggaaat aatctaccta aggtcatttt tttagaagat
    11701 tttattctac caaatatcat cttagaaatt agaaggataa gtcaaaatac agaagttggg
    11761 agtattacaa ccttgagtga ggaagacatg gatatagtag gttttttgaa tgatcatttt
    11821 gtagaaaaaa atactcactc tgtgtctaat ttattattta aagacaaata cttcatgcgt
    11881 tcatttttag ttggagtagt aaatcaaccg tattttaggc ttttagaatc agaaaatgat
    11941 ttacgtgttt tttggaataa ttgtaaatct tctgctgcaa ttttaaaacc tagaaatgaa
    12001 gcaggaagta atggaataaa aaaagtttac cctaacgaga aaattgattc agtgtatttt
    12061 gaaaaaaact atattataga ggaatacatt gatatcgata acatgataac atgtgatggt
    12121 tattcaattg gaagtgagat taagcgattt tatgttcacg aatatgagga actattgttc
    12181 aataccttaa gttctagtgg atattatctt gtaaggacta gttcgttata taatgatagt
    12241 gaaaaaattg aatacataga aaaagcattg gaagaatgtc gcaaagtttt gaatgttttt
    12301 tctatcaatt ctgaaataac cccttttcat tttgaatggt tccttgaatt atcaactggt
    12361 aaaatagtct tttgtgaagt tggaaaaaga tttggagggg gagatattcc ccagttaatt
    12421 gaggatagtc atggagttga tgtaattaaa gaatattggg atattttgac taattcacaa
    12481 gtattgaaaa aaataaattt ttctaaagtg atttctagac ctgctaatat ctcagcaacg
    12541 tttgctttat atagaaagca aggtaaggtt atcgaggtac ctgatgaaaa agaattggct
    12601 tgggcaaaaa aagtgtacat atttattaaa ccaaatactt actataaagt atctgaaaat
    12661 gtagtcgaaa attcaatgtt tgtccaattt aattgcaaaa atagttgtga atttgagaaa
    12721 aggttagatg aacttaagca catatcacaa aagtttaaat atgtgattac tgattcggga
    12781 gaataaaatg attagagaag aacatcacaa tattctatcc attgtagcta gtaggatgat
    12841 atctcgaatc ggagatatca tgtttgattt cgccaataat acctttcttg ctggtcttaa
    12901 tccaacatct ctatcagtgg ttgcaattta tcaatcatta gaaagtatga taggtgttct
    12961 atttaattta tttggtggag ttattgcaga tagtttcaag cggaaaaaaa ttattattac
    13021 tacaaatatc ttatgtggta ttgcttgcat aactctttca tttatatccc aagaaaaatg
    13081 gttggtttat gcgatagtca taacaaatgt cattttggct tttatgagtg ctttttcagg
    13141 gccatcatac aaagctttta cgaaagaaat tgtaaaaaag gacagtatat cataacttaa
    13201 ttcattgcta gaaacaacaa gtactgtgat taaagtaaca attcctatga ttgcaatttt
    13261 cttatataag ttacttggaa tacatggtgt gttattacta gatggattat cgtttttaat
    13321 tgctgcctca ctaattttct tcattactcc tgtaaatgag gaggtggata caaaagagaa
    13381 tatgacgata agaggaatct ttgatgattt aaaaatagga tttacgtatg tatatagtca
    13441 taaacaaatt ctcactataa ttgccctttc agcacttgtt aactttttcc tagcagccta
    13501 taatttgttg ctgccataca gtaatcaaat gtttggaagt atttcaagtg ggctatatgg
    13561 aaccttttta acagccgaag cgattggtgg ctttattggt gcgatattaa gtggatttat
    13621 caataaatcc ttgtcaagca aacgtttaat gctcttttta gcatattcag gtttgatgtt
    13681 aatgctaaca gcgccgatct attatatgtt ccgcaacgtc attattttag cctttactcc
    13741 agcattattt agtctatttc tttccatttt taatatccaa tttttctcta ttgttcaaag
    13801 agacgtagat aatgagtttc ttggcagagt atttggaatc atctttacgg tagctattct
    13861 ttttatgcca ctaggtactg tttttttctc agtagtttta aatcctaaca atacttttaa
    13921 tttttttatt attggtgtat ctattacgat attatcgcta atatttagca cgctattgaa
    13981 gaggtatgat agaagttgat agatgataaa aaatagctga tatagagaat ttagagcgcc
    14041 tttggaatat atttttggaa tttaatcaat cacagttgaa tgtgaagggc aatccttttt
    14101 agaagaatac aatcaagata ccattatgct atttctttag ttcagttaaa atattgagaa
    14161 gtattacttt tattgaaaaa gcatcacaaa ggactccaat taatttttaa tgatttttct
    14221 aatctaattt tgtggttatt gacaaataaa gtctagttaa ttgctttgaa atccatggag
    14281 tggtctatat acatctgtta atgcaacgga aaattttatt gataagtagg gggtggctat
    14341 tattcagctt ttaggttctg aaagtaagag attcacatta gaaatatcat gttgaccatt
    14401 tttcaatttg ctggttagta gtaatctgga catcattaat cccttcctta acaaaattat
    14461 gtgacttttg ttaccggatt actgctgatt ttttaatagc ttataacatc tttagacggt
    14521 taatagattt tgaccgtctt tcttaatatt gtcttaccta taatagatat gcttatgaga
    14581 tatgtttaat aaattaattt tagttcaaaa tgtccagttt ggacactttg aatgatttct
    14641 tagttttata tattatactt ttctcaggag aaagctagat gtacagacgt ttgagagatt
    14701 tgagggaaga tcacgatttg acccaaaaac aaatagctaa aatactttcg tttacagact
    14761 cagcttatgc taaaattgaa cggggtgagc atacgttaac agcagatata ttggtaactc
    14821 tctcaaactt ttacgatgtc agtacagact acctattggg attgacggat tttcctgata
    14881 aaattcgctt tagaaaataa tctcctcaat ttcatagagt gtgaaaatgc gaagattttt
    14941 tttatttgtt ctttgacaat tgaatagtcc aaaatggtac tttcctcatt tgtggagcag
    15001 atttgaatgg ttcgccatga taagagcgat attaaaacca tcaataaaat agagcgatac
    15061 tttatatgcc atgatacaaa tgatatacaa tgatacttct gaccgttcag gctgccaccg
    15121 taaaagagca gcaagtgaaa ttcttatgat gacttcatca gtcatgccat gttgaatgtg
    15181 tgagtttgtt agataaacgc aattaatcct caaaaggttc cccgaacctt ttgagttcta
    15241 cagacgcatc acgtggagtg tgtaagcttg ttgctaaaag cgtaaaaacc ttggaacgaa
    15301 aggaataata gacttcctgc gaaacaaaaa tataatacaa taaaactatg aatgatgaag
    15361 caagtaaaca attgagcgat agccgtttca agatccttgt aggtgttcag cgcacgactt
    15421 ttgaagagat gttagcggtg ttaaaaacag cttatcaacg taaacgcgca aaaggtggac
    15481 gaaaaagcaa attaagccta gacgatctcc ttatggtaac tattcaatac atgcgagaat
    15541 agcgcactta tgaacaaatt gcggctgatt ttggcattca cgaaagcaac ataattagtc
    15601 ggagtcaatg gattgaagca actcttattc aaaatggttt tacgatttca aattctgcct
    15661 taattctgta aaaacagtaa aattcgaagg attgtaaggt aagagttttt ttctttctga
    15721 aaaaatggta taatagcaat caaaactaga aaataaaacg gaatttggaa cagatttgtc
    15781 tgtatcctag tagagtggtg atactatgaa gattagtaag aggcacttat taaattattc
    15841 catcttgatt ccctacttgc ttttatctat tttgggcttg attgtggtct attcgaccac
    15901 cagtgctatt ttaattgaag aaggcaagag cgccttgcag ttggttcgaa accaaggaat
    15961 cttttggatt gttagtttga tactgattgc cttaatttat aaattgagac tagatttttt
    16021 gagaaatgag cgactaatca ttttagttat attaatagaa atgcttttat tgttcttggc
    16081 tcgttttatt ggtatttcag taaacggggc atacggttgg atttcggttg caggagtaac
    16141 tattcagcca gctgagtact taaaaatcat tattatttgg tatttagctc accgattctc
    16201 caaacagcaa gaagaaatag ctacttatga ttttcaagtt ttgactcaaa atcaatggct
    16261 tccccgtgct tttaatgatt ggcgattcgt tctcctagtt ctgattggaa gtttgggaat
    16321 tttccctgat ttaggaaatg cgactatttt agtcttggtt tccttgatta tgtatacagt
    16381 tagtggaatc gcttatcgct ggttttcaac cattctggcg ctcgtatctg ccacttctgt
    16441 ctttgtcttg accactatca gcctaatcgg tgttgagacc ttttcaaaaa ttccagtatt
    16501 tggctatgta gccaagcgct ttagtgcctt ttttaatcct tttgccgatc gtgctgatgc
    16561 aggtcaccag ttagctaatt cttattttgc catggtcaat ggcggttggt ttggtctagg
    16621 tcttggaaac tcgattgaaa aacgaggtta tttgccagaa gctcatacag actttgtctt
    16681 ttctatcgtg attgaagaat ttggctttgt tggtgccagt cttattttag ctctcttgtt
    16741 tttcatgatt ttgcggatta tcttggtcgg tatccgagcg gagaatcctt tcaatgccat
    16801 ggttgcactc ggtgtcggag ggatgatgtt ggttcaggta tttgtcaata tcggagggat
    16861 ttcgggcttg attccatcta caggagtgac tttccccttc ttatcccagg gtggaaatag
    16921 tcttctagtc ttatcagtgg cagtagcctt tgtcttaaat attgatgcca gtgaaaaacg
    16981 cgctaaattg taccgagaat tggaaaatca accaatgaac cttctgttga agtaggataa
    17041 agaaaggata gtttatgtct cttcaaaaat tagaaaatta tagtaataaa agtgttgtgc
    17101 aagaagaagt cttgattcta acagaattac tggaagatat tactaaaaat atgcttgccc
    17161 cagagacctt tgaaaaaata atacagttga aagaattatc aacgcaggaa gattatcaag
    17221 gtctaaaccg tctagtgact agcttatcaa atgatgaaat ggtctatatt tcacgctatt
    17281 tctctatctt gcctcttttg attaatattt cagaggatgt ggatttagct tatgaaatca
    17341 atcatcaaaa taatattgat caggactatt taggtaaatt atctacaacg attaaattgg
    17401 tagcagaaaa ggaaaatgcc gttgagatcc tagaacactt gaatgttgtc cctgttttga
    17461 cagcccatcc aacacaagtg caacgcaaaa gtatgttgga tttaacaaat catattcata
    17521 gtcttttgcg taaataccgt gatgttaagt tggggttgat caataaagat aaatggtaca
    17581 atgatttgcg tcgttacatc gaaattatca tgcagacaga catgattcgt gagaaaaaat
    17641 taaaagtgac taacgaaatc acgaatgcta tggaatatta taacagctcc tttttgaaag
    17701 ctgtacctca tttgacgacg gagtataagc gcttagcgca agcgcatggt ctgaatttaa
    17761 aacaggctaa accaatcacc atgggtatgt ggataggtgg tgaccgtgat ggaaatccat
    17821 ttgttacagc aaagaccttg aagcagtctg cactcactca gtgtgaagtc atcatgaact
    17881 actatgataa aaagatttac caactttatc gtgaattttc tctttcaact agcattgtca
    17941 acgtcagcaa gcaagtcaga gaaatggctc gtcaatccaa ggataactcg atttaccgcg
    18001 aaaaagagct ttaccgtcgt gccttgtttg atattcaatc aaaaattcag gcaactaaaa
    18061 cctatctgat tgaggatgaa gaagttggga ctcgttatga aaccgccaat gatttctaca
    18121 aggatttgat tgccattcga gattctctac tagaaaataa gggcgagtcc ttgatttcag
    18181 gtgattttgt ggaattattg caggcagtag agatatttgg tttttactta gcatcaattg
    18241 atatgcgaca agactctagc gtctatgaag cctgtgtggc agaactcttg aaatcagcag
    18301 gaattcattc tcgttatagc gagttgagcg aagaagaaaa gtgtgacctt ctcttgaaag
    18361 aattagaaga agatccccga attctttctg cgactcacgc agaaaaatca gaattattag
    18421 caaaagaatt agctattttt aagacggctc gtgttttgaa agataagttg ggagatgatg
    18481 tcatccgtca gaccatcatt tcacatgcaa ccaacctttc tgatatgcta gaattagcta
    18541 ttctgttaaa agaagtagga ctggtggata cggaaagggc gcgtgttcag attgttcccc
    18601 tttttgaaac aattgaagac ttggatcatt cagaggaaac aatgagaaaa tatctttctc
    18661 ttagccttgc caaaaaatgg attgactcac gaaataacta ccaagaaatc atgcttggct
    18721 actctgacag taataaagat ggcggttact tgtcatcatg ttggaccctc tacaaggctc
    18781 aacaacaatt gactgctatt ggagatgaat ttggcgttaa ggttaccttc ttccatggtc
    18841 gtggtggtac tgtcggtcgt ggtggtgggc caacctatga agccattaca tctcaaccgc
    18901 tcaagtctat caaggatcgt atccgtttga cggagcaggg tgaagtaatt gggaataaat
    18961 acggtaacaa agacgccgct tactataacc ttgaaatgct agtatcggca gctattaacc
    19021 gtatgattac tcagaagaag agcgatacca ataccccaaa tcgttatgaa gccattatgg
    19081 atcaagtagt ggaccgtagt tacgatatct accgtgattt ggtctttggt aatgagcatt
    19141 tctatgatta tttcttcgag tcaagtccaa tcaaggctat ttcaagtttt aatattggtt
    19201 ctcgtccagc cgctcgtaag actattactg aaatcggtgg tttgcgtgcc atcccttggg
    19261 tattctcatg gtcacagagt cgtgttatgt tccctggatg gtacggggtt ggttcaagct
    19321 tcaaggaatt tatcaataaa aatccagaga atattgctat cttacgagat atgtaccaaa
    19381 attggccttt cttccaatcg cttctttcaa atgttgatat ggttttgtca aaatcaaata
    19441 tgaatattgc ttttgaatat gctaaacttt gtgaagacga gcaagttaag gccatctatg
    19501 agattatttt aaatgaatgg caagttacta agaacgttat cttggctatt gaaggacatg
    19561 acgaactctt agctgacaat ccatatctaa aagctagtct ggattaccgt atgccttact
    19621 ttaatattct caactatatt cagttagagt tgattaaacg ccaacgtcgt ggagaattgt
    19681 ccagtgatca agaacgattg attcatatca ccatcaacgg aattgcgaca ggattgcgta
    19741 attcaggttg ataattttca agagtgaatg ctaaaagtga atatcaaaaa aattctaata
    19801 gactattgac aagtagttta aaaatgatat aatttaacca ttcagaaaag taatcataca
    19861 aactttttag agagtctgtg gtagctgaaa acagataagt ggcgatgatg aaaattgggc
    19921 tgaatgctat ttagaatttg aaattataaa aattcggtaa gcacacctta cagtgcatct
    19981 cgttattgcg agactgagcg atagggaaat tccctataat tgaggtggta ccgcgcatcg
    20041 acgtcctcac acaagttttt tgtgtgagga tttttttgat ggaggttagt atggaaagaa
    20101 aacgatggcg tcgcttgttt agataagtga aatatgttaa aggaaataaa aaggagaaac
    20161 agaatgaaaa ataaacgttt aattggaatt attgctgcat tagcagtctt agtagcagga
    20221 agcttgattt attcttcaat gaataaatca gaagctcaga ataataagga tgagaagaaa
    20281 ataactaaga ttggtgtgct tcaatttgtg agccatccat cccttgattt gatttataaa
    20341 gggatccaag atggacttgc agaagaagga tataaagatg atcaagttaa aattgatttt
    20401 atgaactcag aaggtgacca aagtaaggtt gcgacaatga gtaaacaatt ggttgcaaat
    20461 gggaatgacc ttgtggttgg tatcgcaaca ccagcagccc aagggttggc tagtgcaaca
    20521 aaagacctac cggttatcat ggccgctatt acagacccaa ttggtgctaa cttggttaaa
    20581 gatttgaaaa aaccaggtgg caacattaca ggggtatctg accacaatcc agctcaacaa
    20641 caagttgaac tcatcaaggc tctgacaccg aatgtgaaaa caatcggagc tctttactca
    20701 agtagcgaag acaattcaaa aacacaggtc gaagaattta aggcttatgc tgaaaaagca
    20761 ggtctgacag tggaaacatt tgcagttcct tcaacaaatg aaattgcctc aactgtcact
    20821 gttatgacta gcaaggtaga tgctatttgg gttccaattg ataacaccat tgcatcagga
    20881 tttccaacgg ttgtctctag caatcaaagt tctaagaaac caatttatcc cagtgcgaca
    20941 gctatggtag aagtaggtgg tttggcatca gttgtaattg accaacatga ccttggtgtg
    21001 gcaacaggta aaatgattgt gcaagtcttg aaaggtgcaa aaccagccga taccccagtc
    21061 aatgtctttt caactggtaa gtcagtcatc aataaaaaaa tagcacaaga actaggtatt
    21121 actatccctg agtctgttct caaagaagca ggacaagtca tcgaataaat aaggtaggga
    21181 ggaggagact cttcccattt tttaaaaaga tgaatataga aaggattaaa taaaatatga
    21241 ttgtttccat tatttctcaa ggatttgtct gggctattct aggtctggga atctttatga
    21301 catttaggat tttaaacttt ccagatatga cgacagaagg ttccttccct cttgggggag
    21361 ctgttgctgt cactttgata accaaaggcg tgaacccatt tttagcgaca cttgttgctg
    21421 taggagcagg ttgtttggct ggaatggcag caggccttct ttatacaaaa gggaagatcc
    21481 caaccttgct ctcagggatt ttggtgatga cttcttgtca ctcaatcatg ctcttgatta
    21541 tgggacgtgc gaatttaggc ctgcttggaa ccaagcaaat tcaggatgtt ttgccttttg
    21601 attcggattt gaatcaactc ttgacaggtc tcatctttgt gagtattgtt attgctctca
    21661 tgctcttttt cttggacact aaactcggac aagcctatat tgctacaggg gataatcctg
    21721 atatggctag aagtttcggg attcatactg gacgcatgga gctcatgggc ttggtcttat
    21781 caaatggtgt gattgccctt gcaggtgccc tcattgctca gcaagaaggt tatgccgatg
    21841 tgtctcgagg gatcggggtt atcgttgtgg ggcttgcaag tttgattatt ggagaagtta
    21901 ttttcaagag tttgagcttg gcagagcgtt tggttactat cgttgtaggt tctatcgctt
    21961 atcaattttt agtgtgggca gttatcgcac ttggctttaa tacaagttac cttcgtttat
    22021 acagtgcctt gattttagca gtctgcctca tgattccaac atttaagcaa acaatcttga
    22081 aaggagccaa gttaagcaaa tgacagcaat tgtagaatta aaaaatgcaa ccaaaatcgt
    22141 taaaaatggc tttgatgaag aaaagattat tttaaatgat gtttccttag aaatttttga
    22201 acgggacttt atcacgattt tgggcggaaa tggtgctgga aaatcaaccc tctttaacac
    22261 tatagcaggg accttatcac taactagtgg aactatccgt attttaggtg aagatctcac
    22321 taagttttca cccgagaagc gtgccaagta cctgtctcgt gtcttccaag atccaaagat
    22381 ggggacagct ccccgtatga cggtcgctga aaatctttta atcgccaagt ttcgtggtga
    22441 aaagcgtgga ttgttaccac gacgcttgac tagctataag gatgaatttc aggtaaccat
    22501 tgaaaaagta ggaaatggtc ttgagaaaca cttgaataca ccgattgagt tcttatcagg
    22561 tggacaaaga caggctttga gtctcttgat ggcaaccttg aagcgacctg aattactcct
    22621 gttagatgag catactgctg ccctggatcc aaagactagt gttgctttga tggaattgac
    22681 agatgaattt gttaagaaag atcagctaac agcccttatg attactcatc atatggaaga
    22741 tgctctcaaa tacggcaatc gcttgattgt catgaaagaa ggacggatta tccaagattt
    22801 aaaccaagaa gaaaaagcaa aaatgaaaat ctctgattat tatcaactct ttgaataaag
    22861 tagggaaaat gagtgaaata gtttactttt tttctgaaat aaagtatact atatatagta
    22921 tactatgata acatggaggt attgtgtatg gttgacaaac aagtcattga agaaatcaaa
    22981 aacaatgcca acattgtgga agtcatagga gatgtgattt ctttacaaaa ggcaggacgg
    23041 aactatctag ggctctgtcc ttttcatggc gaaaaaacac catctttcaa cgttgtagag
    23101 gataagcagt tttatcactg tttcggttgt ggtcgctcag gtgatgtctt taagttcatc
    23161 gaggagtacc aaggggttcc ctttatagag gcagtccaaa tcttaggtca gcgtgttgga
    23221 attgaggttg aaaaaccgct ttatagtgag cagaagtcag cctcacctca ccaagctctt
    23281 tatgatatgc acgaagatgc agccaaattt taccatgcta ttctcatgac aacgactatg
    23341 ggagaagagg ccagaaatta cctttatcag cggggtttga cagatgaagt gcttaaacat
    23401 ttttggattg gtttagcacc tccagaacga aactatctct atcaacgttt gtctgatcag
    23461 tatcgtgaag aggatttact ggattcaggc ctgttttatc tctcggatgc caatcaattt
    23521 gtagacacct ttcacaatcg cattatgttt cccctgacaa atgaccaagg aaagatcatt
    23581 gccttctcag gtcgtatctg gcaaaaaacg gattcacaaa cttctaagta taaaaacagc
    23641 cgatcgactg caatttttaa caaaagttac gaattatatc atatggatag ggcaaaaaaa
    23701 tcttctggaa aagctagtga gatttacctg atggaaggat tcatggatgt tattgcagcc
    23761 tatcgggttg gaatcgaaaa tgctgtggcg tcgatgggaa cggccttgag tcgagagcat
    23821 gttgagcatc tgaaaaggtt aaccaagaaa ttggttcttg tttacgatgg agataaggct
    23881 gggcaagccg cgatattgaa agcattggat gaaattggtg atatgcctgt gcaaatcgtc
    23941 agcatgcctg ataacttgga tcctgatgag tatctacaaa aaaatggtcc agaagacttg
    24001 gcctatctat taacgaaaac tcgtattagt ccgattgagt tctacattca tcagtacaaa
    24061 cctgaaaaca gtgaaaatct gcaggctcag attgagttta ttgaaaaaat agctcccttg
    24121 attgttaaag aaaagtccat cgctgctcaa aacagctata ttcatatttt agctgacagt
    24181 ctggcgtcct ttgattatgc ccagattgag cagattgtta atgagagtcg tcaggtgcaa
    24241 aggcagaatc gcatggaaag aatttccaga ccgacgccaa tcaccatgcc tgtcaccaag
    24301 cagttatcgg ctattatgag ggcagaagcc catctactct atcggatgat ggaatcccct
    24361 cttgttttga acgattaccg tttgcgagaa gactttgcat ttgctacacc tgaatttcag
    24421 gtcttatatg acttgcttgg ccagtatgga aatcttcctc cagaagtttt agcagagcag
    24481 acagaggaag ttgaaagagc ttggtaccaa gttttagctc aggatttgcc tgctgagata
    24541 tcgccgcagg aacttagtga agtagagatg actcgaaaca aggctctctt gaatcaggac
    24601 aatatgagaa tcaaaaagaa ggtgcaggaa gctagccatg taggagatac agatacagcc
    24661 ctagaagaat tggaacgttt aatttcccaa aagagaagaa tggagtaata atggcaacaa
    24721 aacaaaaaga agtaacaaca tttgacgtac aggtagcaga atttatccgt aatcataagc
    24781 aaaaagggac agcaacagat gatgaaatca atgcaagttt ggttattcct tttaccttgg
    24841 acgctgatgg gattgaagat ctcttgcaac ggattcagga tgcaggaatt tctatcacag
    24901 ataacgaagg aaatccaagt gcgcgtgttc ttagcaatga agaagaacca gaactcagcg
    24961 atgaggactt gattgggtca acttctgcta aggtcaatga ccctgtccgt atgtacttga
    25021 aagaaatagg ggtcgttcct ctcttgacca atgaagagga gaaagagttg gcactggctg
    25081 ttgaagctgg tgatatcgaa gccaaacaac gtcttgcgga agccaatctt cgtttggttg
    25141 tttccattgc caaacgctat gtcggtcgtg gtatgcagtt ccttgacttg attcaagaag
    25201 gaaatatggg cttgatgaag gcggttgaca agtttgacta ttctaaaggg ttcaagtttt
    25261 caacttatgc aacttggtgg attcgtcagg ctatcactcg tgctattgcg gaccaagctc
    25321 gtaccatccg tatcccagtt cacatggttg aaactatcaa taaattggtt cgtgaacagc
    25381 ggaatctcct tcaagaattg gggcaagatc cgacaccaga acagattgct gaacgaatgg
    25441 atatgacacc tgataaggtt cgtgaaatct tgaagattgc ccaagaacca gtatctcttg
    25501 aaactcctat cggtgaagag gacgatagcc acctcggaga ctttatcgaa gatgaagtga
    25561 ttgaaaatcc agtggattat acgactcgta tcgtcttgcg tgagcaattg gatgaaatct
    25621 tagatactct tacagaccgt gaagaaaatg ttctgcgtct acgttttgga ctagatgatg
    25681 gaaaaatgcg cacacttgaa gatgtgggga aagtctttaa cgtaactcgt gagcgtatcc
    25741 gtcagattga agcaaaggct ttgagaaaac tacgccaacc aagtcgtagc aaaccgcttc
    25801 gtgattttat tgaagactaa gagtgaggaa aatatggctt atacagaaga gcaaattgaa
    25861 aacatcaaaa cacggatttt aacagccttg gaagaagtca tcgaccctga gttgggaatc
    25921 gatattgtca atcttggttt gatctatgag attcgttttg acggtgacac agggcaaaca
    25981 gagattgaca tgactttgac aactatgggt tgtcccttag cagacctttt gacagaccag
    26041 atttatgatg ctatgataga ggttccagaa gtaacggata ctgaggttaa attagtctgg
    26101 tatccagcct ggacagttga aaaaatgagt cgctatgccc gcattgccct aggcattaag
    26161 taaacatata aaagcatgtg agagactgtt ggaaaagcga ggaaatttcc ccacttttcc
    26221 tctagtctct cctttctttt gctgatttta ttcaaagaaa atgatataat agtagttatg
    26281 gagaaaaaga aattacgcat caatatgttg agttcaagtg agaaagtagc aggacaggga
    26341 gtttcaggtg cttaccgtga attagttcgt cttcttcacc gtgctgccaa ggaccaattg
    26401 attgttacag aaaatcttcc aatcgaggca gatgtgactc actttcatac gattgatttt
    26461 ccctattatt tatcaacctt ccaaaagaaa cgctcaggga gaaagattgg ctatgtgcat
    26521 ttcttgccag ctacacttga gggaagtttg aaaattccat ttttcttaaa gggaattgtg
    26581 aaacgctatg tattttcttt ttacaaccgg atggagcact tggttgtggt caatcctatg
    26641 tttattgagg atttggtagc agctggtatt ccacgtgaaa aagtgaccta tattcctaac
    26701 tttgtcaaca aggaaaaatg gcatcctcta ccacaagaag aggtagttag actgcgcaca
    26761 gatcttggtc ttagtgacaa tcagtttatc gtagtaggtg ctgggcaagt tcagaaacgt
    26821 aaagggattg atgactttat ccgtctggct gaggaattgc ctcagattac ctttatctgg
    26881 gctggtggct tctcttttgg tggtatgaca gatggttatg aacactataa gaaaattatg
    26941 gaaaatcccc ctaaaaattt gatttttcca ggcattgtat cgccagagcg gatgcgcgaa
    27001 ttgtatgctc tagcggatct tttcttgttg cctagttaca atgagctctt tcctatgact
    27061 attttagaag ctgcgagttg tgaggctcct attatgttgc gtgatttaga tctctataag
    27121 gtgattttgg agggaaatta tcgggcgaca gcgggtagag aagagatgaa agaggctatt
    27181 ttggaatatc aagcaaatcc tgctacctta aaagatctca aagaaaaggc taagaatatt
    27241 tccagagagt attctgaaga gcatctgtta caaatctggt tggactttta tgagaaacaa
    27301 gccgctttag ggagaaagta aaaagtgagg taatctatgc gaattggttt atttacagat
    27361 acctattttc ctcaggtttc tggtgttgcg accagtattc gaaccttgaa aacagaactt
    27421 gaaaagcagg gacatgctgt ttttatcttt acgacgacag ataaggatgt caatcgctac
    27481 gaagattggc aaattatccg cattccaagt gttcctttct ttgcttttaa ggatcgtcgc
    27541 tttgcctacc gaggttttag caaggcactt gaaattgcta aacagtatca gctagatatt
    27601 atccatactc agacagaatt ttctcttggc ctgttgggga tttggattgc gcgtgaattg
    27661 aaaattccag tcatccatac ctatcacacc cagtatgaag actatgtcca ttatattgct
    27721 aaggggatgt tgatccggcc gagtatggtc aagtatctgg ttagaggttt cctgcatgat
    27781 gtggatgggg ttatttgccc tagtgagatt gtccgtgact tgctatctga ttataaggtc
    27841 aaggttgaaa aacgggtcat tcctactgga attgaattag ccaagtttga gcgtccggaa
    27901 atcaagcagg aaaatttgaa agaactgcgt agtaaactag ggattcaaga tggtgaaaag
    27961 acgttgctta gtctttcgag aatctcctat gaaaaaaata ttcaagcagt tttagtagcc
    28021 tttgctgatg ttctgaaaga ggaagacaag gttaaactgg tagtagctgg ggatggccct
    28081 tatctgaatg acctcaaaga gcaagcccag aacctagaga ttcaagactc agtcatcttt
    28141 acagggatga ttgctcctag tgagacggct ctttactata aagcggcgga tttcttcatt
    28201 tcggcatcga caagcgaaac gcaaggtttg acctacttgg aaagcttagc cagtggaaca
    28261 cctgtcattg ctcacggaaa tccttatttg aacaacctca tcagtgataa aatgtttgga
    28321 accttgtact atggagaaca tgatttggct ggtgctattt cggaagccct gattgcaaca
    28381 ccagacatga atgagcatac cttatcagag aaattgtatg agatttcagc tgagaacttt
    28441 gggaaacgag tgcatgagtt ttatctggat gccattattt caaataactt ccagaaagat
    28501 ttggctaaag atgatacggt cagtcagcgt atctttaaga cagttttgta tcttccgcaa
    28561 caggtggttg ctgtacctgt aaaaggatct agacgcatgt tgaaggcttc aaaaacacag
    28621 ttgatcagta tgagagacta ttggaaagac catgaagaat agaaagagga acagctatga
    28681 aaaaaacaat taatgagaag cggtcgtgat aaaaagattg cgggtgtttg tgctggggtg
    28741 gcccattatc tggatatgga tccgactatc gttcaagtca tttggggtgt tcttacttgc
    28801 tgttacggag ctggaattgt agcttacatt attttatgga ttatcgcacc agtagcaact
    28861 gactattgaa aactagctca attcatgcta agataataga aaatagaatg taacgaagga
    28921 gagaaaaatg gcatttggag ataatggaaa tcgtaaaaaa actatgtttg agaaaataac
    28981 cttgtttatc gtgattatca tgctagtagc aagtttattg ggaatttttg caactgcaat
    29041 tggtgccctc agtaatctat aaaatagatt caagaaaatt tagtgactgg gatttcccag
    29101 ccctttttta aagtgagaag aaataatgag tatgttttta gatacagcta agattaaggt
    29161 caaggctggt aatggtggcg atggtatggt tgcctttcgt cgtgaaaaat atgtccctaa
    29221 tggaggccct tggggtggtg atggtggtcg tggaggcaat gtggtcttcg ttgtagacga
    29281 aggactacgt accttgatgg attttcgcta caatcgtcat ttcaaggctg attctggtga
    29341 aaaagggatg accaaaggga tgcatggtcg tggtgctgag gaccttagag ttcgagtacc
    29401 acaaggtacg actgttcgtg atgcggagac tggcaaggtt ttaacagatt tgattgaaca
    29461 tgggcaagaa tttatcgttg cccacggtgg tcgtggtgga cgtggaaata ttcgtttcgc
    29521 gacaccaaaa aatcctgcac cggaaatctc tgaaaatgga gaaccaggtc aggaacgtga
    29581 gttacaattg gaactaaaaa tcttggcaga tgtcggttta gtaggattcc catctgtagg
    29641 gaagtcaaca cttttaagtg ttattacctc agctaagcct aaaattggtg cctaccactt
    29701 taccactatt gtaccaaatt taggtatggt tcgcacccaa tcaggtgaat cctttgcagt
    29761 agccgacttg ccaggtttga ttgaaggggc tagtcaaggt gttggtttgg gaactcagtt
    29821 cctccgtcac atcgagcgta cacgtgttat ccttcacatc attgatatgt cagctagcga
    29881 aggccgtgat ccatatgagg attacttagc tatcaataaa gagctggagt cttacaatct
    29941 tcgcctcatg gagcgtccac agattattgt agctaataag atggacatgc ctgagagtca
    30001 ggaaaatctt gaagaattta agaaaaaatt ggctgaaaat tatgatgaat ttgaagagtt
    30061 accagctatc ttcccaattt ctggattgac caagcaaggt ctggcaacac ttttagatgc
    30121 tacagctgaa ttgttagaca agacaccaga atttttgctc tacgacgagt ccgatatgga
    30181 agaagaaact tactatggat ttgacgaaga agaaaaagcc tttgaaatta gtcgtgatga
    30241 cgatgcgaca tgggtacttt ctggtgaaaa actcatgaaa ctctttaata tgaccaactt
    30301 tgatcgtgat gaatctgtca tgaaatttgc ccgtcagctt cgtggtatgg gggttgatga
    30361 agcccttcgt gcgcgtggag ctaaagatgg ggatttggtc cgcattggta aatttgagtt
    30421 tgaatttgta gactaggaga ctggtatggg agataaaccg atatctttcc gagatgcgga
    30481 tggtaatttt gtttccgccg cagacgtttg gaatgaaaag aaattggaag aactatttaa
    30541 tcgtctcaat ccaaatcgtg ccttgagatt ggcacgaact aaaaaggaaa atccatctca
    30601 gtaaagaagc taaaaaatcc cgtgcctcat cagacacggg attttgtggt acgacaggca
    30661 tgtatagcaa actgaatctg gaatagcaca gcatatcttc taaaatattg ttataaattg
    30721 atttgaattt caaaattaaa ttgtttgatt cttatttcaa tttgttatag tatatctgat
    30781 gtcaaagttc tcggcgagtc aaatagcgat tcccaagcct gactatcgtg aggtagcgga
    30841 ttaaaatggt ctggggatag accgttttaa gtctgacgct ggaaataaga attgtcagaa
    30901 gaagggatag cgaaatcgtg gctctacgaa caggaacgtg ataataaggc gtatatagcg
    30961 gataagaggg cctcaaactc taaagtccaa aaaggtagtc gtaacctata tgcgtaaatc
    31021 acgagagtaa ttgaattcgt actaagattt tctattttca ctgtaacctt ttaacgtcct
    31081 tatatcttgt atacacgagg aaagatgtac gacttatccc gtgaggtcta tcactataaa
    31141 gagaaaacga cagatagaag tgatcctgag tcacggttat ctttaaaata gattgtctga
    31201 taggacggta tgtataaaac gcttctgtga actgagagaa gggggagaag ttcttgctaa
    31261 aatttagttg aacagccgta ttccgatact tagataagag atctagtctt agctcctact
    31321 cggtttcagg ggataaaaaa ggggcaatag cgattcgaga aagattatac tcttcgaaaa
    31381 tctcttcaaa tcacgtcaat atcgccttgc cgtacgtgta ggatactgac tacgtcagt
//
LOCUS       DAVBOM010000024        30962 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBOM010000024 DAVBOM010000000
VERSION     DAVBOM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.024"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            289..2790
                     /locus_tag="VQ878_001148"
     CDS             289..2790
                     /locus_tag="VQ878_001148"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET3095490.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK"
     gene            2984..3679
                     /locus_tag="VQ878_001149"
     CDS             2984..3679
                     /locus_tag="VQ878_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095491.1"
                     /translation="MPVNEYGRMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3691..4107
                     /locus_tag="VQ878_001150"
     CDS             3691..4107
                     /locus_tag="VQ878_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095492.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4922..5014)
                     /locus_tag="VQ878_001151"
     CDS             complement(4922..5014)
                     /locus_tag="VQ878_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET3095493.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ878_001152"
     CDS             5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ878_001152"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET3095494.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6127..6699
                     /locus_tag="VQ878_001153"
     CDS             6127..6699
                     /locus_tag="VQ878_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET3095495.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6930..7688
                     /locus_tag="VQ878_001154"
     CDS             6930..7688
                     /locus_tag="VQ878_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET3095496.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7697..8500
                     /locus_tag="VQ878_001155"
     CDS             7697..8500
                     /locus_tag="VQ878_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET3095497.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8522..9781
                     /gene="rseP"
                     /locus_tag="VQ878_001156"
     CDS             8522..9781
                     /gene="rseP"
                     /locus_tag="VQ878_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET3095498.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9794..11647
                     /locus_tag="VQ878_001157"
     CDS             9794..11647
                     /locus_tag="VQ878_001157"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET3095499.1"
                     /translation="MKQSKIPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11746..13125
                     /gene="bglA"
                     /locus_tag="VQ878_001158"
     CDS             11746..13125
                     /gene="bglA"
                     /locus_tag="VQ878_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET3095500.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYVNWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13318..15126
                     /gene="glmS"
                     /locus_tag="VQ878_001159"
     CDS             13318..15126
                     /gene="glmS"
                     /locus_tag="VQ878_001159"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET3095501.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            15398..16447
                     /locus_tag="VQ878_001160"
     CDS             15398..16447
                     /locus_tag="VQ878_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET3095502.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ878_001161"
     CDS             complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ878_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET3095503.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESV
                     ENSSKKNIPVTPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ878_001162"
     CDS             20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ878_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET3095504.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ878_001163"
     CDS             21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ878_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET3095505.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22062..24143
                     /gene="fusA"
                     /locus_tag="VQ878_001164"
     CDS             22062..24143
                     /gene="fusA"
                     /locus_tag="VQ878_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET3095506.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            24247..28638
                     /locus_tag="VQ878_001165"
     CDS             24247..28638
                     /locus_tag="VQ878_001165"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET3095507.1"
                     /translation="MSNSFEILMNQLGIPVEMRQHPALTQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKVLSQDFSNQLLQAYYREAFSEGP
                     CASQSFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEDAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQTKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVERDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGYPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEIGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28740..29003
                     /locus_tag="VQ878_001166"
     CDS             28740..29003
                     /locus_tag="VQ878_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET3095508.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28996..29274
                     /locus_tag="VQ878_001167"
     CDS             28996..29274
                     /locus_tag="VQ878_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET3095509.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29295..29447
                     /locus_tag="VQ878_001168"
     CDS             29295..29447
                     /locus_tag="VQ878_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095510.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            29469..30710
                     /locus_tag="VQ878_001169"
     CDS             29469..30710
                     /locus_tag="VQ878_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET3095511.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30720..30950
                     /locus_tag="VQ878_001170"
     CDS             30720..30950
                     /locus_tag="VQ878_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3095512.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT         8791 a         5924 c         7248 g         8999 t
ORIGIN      
        1 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgaa tacattaatt
       61 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
      121 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      181 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
      241 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
      301 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      361 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      421 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      481 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      541 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      601 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      661 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      721 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      781 gccattgcca atgaagaagt gcttcctgac ggaacttctg aacgtggagg ctatccagtt
      841 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      901 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      961 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
     1021 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtttt ggctcctgaa
     1081 catgaattag tagatgccat cacaagcaca gagcaagcag aagcagtagc agactacaaa
     1141 caccaagcca gccttaagtc agacttggct cgtaccgacc ttgccaaaga aaaaactggt
     1201 gtatggactg gtgcttatgc catcaatcct gtcaatggta aggaaattcc aatctggatt
     1261 gcggattacg ttcttgctag ctatggtaca ggtgcggtaa tggctgtgcc tgcccacgat
     1321 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1381 ggaaatgttg aagaagctgc ctacacagaa gatggccttc acgttaattc agacttccta
     1441 gatggactca acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1501 tgtggacaag agaaggtaac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
     1561 tggggtgagc caatcccaat cattcattgg gaagatggaa cttcaacagc tgtccctgaa
     1621 agtgaattgc cacttgtctt gcctgtaacc aaggatatcc gtccctcagg tactggtgaa
     1681 agtccactag ctaacttgac agactggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1741 cgtcgtgaaa caaatactat gccacaatgg gcaggttcaa gctggtacta cctccgctat
     1801 attgacccac acaatactga gaaattggct gacgaggatc tgctcaaaca atggttgcca
     1861 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
     1921 tggcataaat tcctctatga cctcggtgtt gttccaacta aggaaccatt ccaaaaactc
     1981 tttaaccaag ggatgatttt gggaacaagc tatcgtgacc accgtggggc tcttgtggcg
     2041 actgacaagg ttgaaaaacg tgatggttct ttcttccatg tggaaacagg ggaagagttg
     2101 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgtcaaccc agacgatgtg
     2161 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgttcatggg cccacttgat
     2221 gcttcaatcg cttggtcaga agaaggtctg gaaggaagtc gtaaattcct tgaccgtgtt
     2281 tatcgtttga ttacaagtaa ggaaattatt gcggaaaaca atggtgctct tgacaaggtt
     2341 tataacgaaa ccgttaaagc tgtcacagag caaatcgaat cattgaaatt caacacagct
     2401 attgcccaac ttatggtctt tgtcaacgcc gctaacaagg aagacaagct ctatgtggac
     2461 tatgccaaag gatttatcca attgattgcg ccatttgcac ctcacttggc agaagaactt
     2521 tggcaaactg ttgcagcaac aggtgaatca atctcttacg tagcttggcc aacatgggat
     2581 gaaagtaaat tggttgaaga cgaaatcgaa atcgtcgtcc aaatcaaagg taaagtccgt
     2641 gccaaactca tggttgctaa agacctgtca cgtgaagaat tgcaagaaat tgctcttgct
     2701 gatgaaaaag tcaaggtaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
     2761 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
     2821 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
     2881 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
     2941 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
     3001 tggtcgaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
     3061 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
     3121 tttgctagct gtttatgggc ctgatacgcc tcaggagatg tggacctacc tttttcagga
     3181 gccagtagca gatatggggg agctggttag ccttttacat cagatgttgg ctcgtaagga
     3241 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
     3301 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
     3361 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
     3421 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
     3481 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
     3541 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
     3601 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
     3661 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
     3721 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
     3781 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
     3841 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
     3901 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
     3961 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
     4021 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
     4081 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
     4141 atggtctagt attatatagt cattaaataa agacctccta actttattta ataaaatcct
     4201 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
     4261 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
     4321 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
     4381 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
     4441 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
     4501 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
     4561 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
     4621 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
     4681 gaaaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
     4741 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
     4801 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
     4861 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
     4921 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
     4981 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
     5041 ggtgtagaag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
     5101 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
     5161 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
     5221 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
     5281 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
     5341 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
     5401 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
     5461 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
     5521 gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt agtcgtagtg
     5581 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
     5641 ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat gcccatgctg
     5701 acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc actcatgagg
     5761 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
     5821 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat attattaccg
     5881 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
     5941 tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga actctttctg
     6001 tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac ttgattcaaa
     6061 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
     6121 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
     6181 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
     6241 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
     6301 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
     6361 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
     6421 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
     6481 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
     6541 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
     6601 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
     6661 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
     6721 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
     6781 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
     6841 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataataaa
     6901 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
     6961 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
     7021 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
     7081 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
     7141 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
     7201 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
     7261 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
     7321 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
     7381 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
     7441 caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat ttgcctaagg
     7501 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
     7561 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
     7621 acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
     7681 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
     7741 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
     7801 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
     7861 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
     7921 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
     7981 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
     8041 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
     8101 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
     8161 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
     8221 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
     8281 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
     8341 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
     8401 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
     8461 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
     8521 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
     8581 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
     8641 gggacctaaa atttttgctc acattggtaa ggatggaacg gcctatacca ttcgaatctt
     8701 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
     8761 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
     8821 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
     8881 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
     8941 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
     9001 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
     9061 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
     9121 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
     9181 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
     9241 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
     9301 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
     9361 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
     9421 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
     9481 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
     9541 tggaattgaa aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
     9601 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
     9661 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
     9721 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
     9781 atcgaggaat attatgaaac aaagtaaaat acctatccca acgcttcgcg aaatgccaag
     9841 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
     9901 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
     9961 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctcctg cccttcttag
    10021 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    10081 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    10141 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    10201 gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac gtgagtttat
    10261 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    10321 gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    10381 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    10441 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    10501 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    10561 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    10621 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    10681 agatgttaaa tcaattgatg aagttgcagc tttcctcaat gttccagaag aacaaacgat
    10741 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    10801 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    10861 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    10921 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    10981 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttacttc
    11041 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    11101 ccttaatttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    11161 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    11221 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    11281 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    11341 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    11401 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    11461 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    11521 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    11581 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    11641 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt tttaccttgt
    11701 tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct aagatttcca
    11761 aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg tgtagctggt
    11821 gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa tcgttactat
    11881 aatgggattg gttcagataa gacatcgact ttttatgtaa attgggagcg ggatattgag
    11941 cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc acggattttt
    12001 ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt tttatcgtaa ggtctttgag
    12061 gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga tttacctttt
    12121 gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc ctatgaagac
    12181 tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat tacctttaac
    12241 gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc acataaggtg
    12301 gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag ccgggctgtt
    12361 aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa cttgacaccg
    12421 gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc ggcccttttt
    12481 caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga gttggtagaa
    12541 atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga actcattcgt
    12601 gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt tatggctcct
    12661 cgatttgcta agcatccaga gagtccactc ttaccagaac atttttacga gccttatgtg
    12721 atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca agggatttat
    12781 gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt gactgagaat
    12841 ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca agatgattac
    12901 cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga agatggtgcc
    12961 aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct caacagctat
    13021 aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg tctgaagaaa
    13081 tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg actctgactg
    13141 attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac tataccaatt
    13201 tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc tataaaagat
    13261 gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt atatactatg
    13321 tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat tcaagggctt
    13381 gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga tggtgctgat
    13441 aaccatttag tgaaggcggt tggtcgtatt gcagaattgt ctgccaagac agctggtgtt
    13501 gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc aactgaggac
    13561 aatgctcacc cacaccgctc tgagacagaa cgctttgtct tggtgcataa tggggtgatt
    13621 gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa ggggcagaca
    13681 gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg gctctcagtt
    13741 cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt tgccttggtt
    13801 gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact tttgattggt
    13861 cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg tgaaactaac
    13921 caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag tgtggaagtt
    13981 caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact tgacttgtca
    14041 gatatcggta agggaactta cccttactac atgctcaagg aaattgacga gcaaccaact
    14101 gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt cgtagaccca
    14161 gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc tggaacatct
    14221 taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac accagttgaa
    14281 cttggaatct catctgagtg gggctacggt atgccacttc tcagcaagaa accactcttc
    14341 atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt caaggctaat
    14401 gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct ctcacgtgaa
    14461 gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc aactaaagcc
    14521 tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga agcaaatggt
    14581 aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc tcagtctatc
    14641 gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact tcttgaaaca
    14701 actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat ggaagcaagt
    14761 ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg agaactcaag
    14821 cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt gtcagatcca
    14881 gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg tgccaaagtc
    14941 ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct tacgaccgta
    15001 catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc ttactttgca
    15061 accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc agtaacggta
    15121 gaataagcta aaaaagtcta gttatctagg cctttttctt gtgagcaaat tggttgcttg
    15181 tactcaagat tcgtgttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    15241 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag
    15301 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta gaataatttt
    15361 tcaaattgaa gtacagagat agataaggag aatcacaatg gtagaattgg gaatttcaac
    15421 atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg ctgaacgcat
    15481 tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggatg tatatgggat
    15541 tggtgagcac catcgggcgg attttgcagt atcagcccca gagattgttc tggccgctgg
    15601 ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt caagcatgga
    15661 cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg gacgagcgga
    15721 gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt atgacttgaa
    15781 agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca atgaaaagac
    15841 caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag tttatcctcg
    15901 tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg aatcaacagt
    15961 gaagattgct caggctggtc taccgattgt atatgctatt attggtggta atccacgtta
    16021 ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggtc atgctgacaa
    16081 agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg agcaggcggt
    16141 gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag accgtccgca
    16201 ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg gcgccatgtt
    16261 tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg atttaggatt
    16321 ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg ttctgagagc
    16381 tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg ctatgaaaga
    16441 ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac gaaaattaat
    16501 cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag ttctcttttt
    16561 tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct gcaaatagga
    16621 gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct ggggttacag
    16681 gtatattttt cttgctagag ttttctaccg attcgttttg aaccgcttct tttacagatg
    16741 atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct tggctaggtt
    16801 tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta gcttctggag
    16861 ctgggtcttg atgttcaggc ttggaagggg ttgagtctgg tttctcttct gcagttgact
    16921 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    16981 agcctttttc agtccattca agtcctttcg ggttggcaat tccgactgat cctgcttggt
    17041 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    17101 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    17161 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    17221 ggtggacacg gtctttgata tcttggagac tcttaagtcg gaaggcatct gtagattgac
    17281 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    17341 catctgtagc cttagtccag tcaaacttgt tgactgcgtc gctagaatcg taagaatcat
    17401 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    17461 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    17521 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    17581 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    17641 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgcg atgtattgga
    17701 tgacatctcc agggctgtca gcttcaaagt tagttggctg agcaatgaga tttttaaaga
    17761 tagtgttaac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    17821 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    17881 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    17941 cttcgcctaa catgattaga tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    18001 tagaagcggc gtcatggtct cccatcatat cgaaacggaa tccatccact ttgtaggtat
    18061 caactaggta tttgatagag tcaactagga ggcgtttggt catatggtgg gttgtcccca
    18121 agcgtccacc accaaagcta gttcgaggtg tgccatcggc atccataaag tggtagtagt
    18181 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    18241 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    18301 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    18361 catatcccca gttgtagttg ctgttgcttg aagcatagtc agacaagcgt tcatggtttt
    18421 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    18481 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    18541 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    18601 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    18661 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    18721 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    18781 gacgctcgat ttggtattga taatagtagc cagtgaaatc tgtgattccg agtttgtttg
    18841 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcgagagcg acagttccaa
    18901 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    18961 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    19021 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    19081 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    19141 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    19201 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    19261 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    19321 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    19381 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    19441 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    19501 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    19561 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    19621 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    19681 aagcttcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    19741 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    19801 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    19861 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    19921 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    19981 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    20041 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    20101 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    20161 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    20221 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    20281 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    20341 tctatatcag tatagcatgt agtaaaacaa tatgcaagcg ttttctttga tttgtgaaaa
    20401 aaattcctac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    20461 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    20521 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    20581 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    20641 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    20701 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    20761 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    20821 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    20881 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    20941 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    21001 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    21061 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    21121 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    21181 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    21241 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    21301 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    21361 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    21421 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    21481 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    21541 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    21601 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    21661 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    21721 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    21781 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    21841 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcctgggt tcaaattagc
    21901 taaatcgatt agtattagct ataactcagc ttaccatctc gtaagttgaa accaacaata
    21961 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    22021 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    22081 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    22141 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    22201 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    22261 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    22321 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    22381 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    22441 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    22501 ctgtaagcac acttcacgat cgccttcaag caaatgcaca cccaatccaa ttgccaatcg
    22561 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    22621 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    22681 ctcaagaata ccgtgaaaaa ttggttgaag cagttgctga aactgacgaa gaattgatga
    22741 tgaaatacct cgaaggtgaa gaaattacta acgaagaatt gaaagctggt atccgtaaag
    22801 cgactattaa cgttgaattc ttcccagtat tgtgtggttc agccttcaag aacaaaggtg
    22861 ttcaattgat gcttgatgcg gttattgact accttccaag cccacttgac atcccagcaa
    22921 tcaaaggtat taacccagat acagatgctg aagaaactcg tccagcatct gacgaagagc
    22981 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    23041 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaacact tctaaaggta
    23101 aacgtgaacg tatcggacgt attcttcaaa tgcacgctaa cagccgtcaa gaaattgaaa
    23161 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    23221 cattgacaga tgaaaaagct aaaatcatcc ttgagtcaat caatgttcca gaaccagtta
    23281 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    23341 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    23401 cagttatctc tggtatgggt gagcttcacc ttgacgtcct tgttgaccgt atgcgtcgtg
    23461 agttcaaagt tgaagcgaac gtgggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    23521 cttctactca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    23581 atgtatggat tgaatttact ccaaacgaag aaggtaaagg attcgaattt gaaaacgcaa
    23641 tcgtcggtgg tgtggttcct cgtgaattta tcccagcagt tgaaaaaggt ttggtagaat
    23701 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aaactttacg
    23761 atggttcata ccacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttg
    23821 ctcttaaaga agctgctaaa tcagcacaac cagcgatcct tgagccaatg atgcttgtaa
    23881 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    23941 gacgtgtaga tggtatggaa gcacatggta acagccaaat cgttcgtgct tacgttccac
    24001 tcgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    24061 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaatcatta
    24121 agaaaaacaa aggtgaagac taatcagtcc tcactctaga aggaagtcac ttagtggctt
    24181 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    24241 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatacc tgttgaaatg
    24301 agacagcatc ctgctttaac acaggcagat attgagcgag tcgtggttca taaaattagt
    24361 aaggtatggg agtttcattt cgtattttct aatattttac cgattgaaat ctttttagaa
    24421 ttaaagaaag ggctgagtga ggaattttct aagacaggca ataaagctgt tttcgaaatc
    24481 aaggttctgt ctcaagattt ttcaaatcaa ctcttgcagg cttattatag agaagctttt
    24541 tctgagggtc catgtgctag tcaaagtttt aagtctcttt atcaaaattt gcaagttcgt
    24601 gctgagggga atcaactctt tattgaagga tctgaggcga ttgataagga acactttaag
    24661 aaaaatcacc ttcctaattt agcaaaacaa cttgaaaagt ttggttttcc aacttttaac
    24721 tgtcaggtcg agaagaatga tgtgctgacc caagagcagg aagatgcctt ccatgctgaa
    24781 aatgagcaga ttgttcaagc ggccaatgag gaagcgctcc gtgctatgga acaactagaa
    24841 cagatggcgc cacctccagc ggaagagaaa ccagcctttg attttcaaac gaaaaaagct
    24901 gcagctaaac ccaagctaga taaggcggag attactccta tgatcgaagt gacgacggag
    24961 gaaaatcgtc tggtctttga aggggttgtg tttgatgtgg agcaaaaagt gaccagaaca
    25021 gggcgtgttt tgatcaactt taaaatgacg gactacactt caagtttttc gatgcaaaag
    25081 tgggtaaaaa atgaggaaga ggctcagaaa tttgatctca tcaagaagaa ttcttggctc
    25141 cgagttcgtg ggaatgtgga gatgaataac ttcacacgcg atttgactat gaatgtgcag
    25201 gatgtgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    25261 gttgagtttc acgctcatac taacatgtcg actatggatg ctctaccaga ggttgaagaa
    25321 atcgttgcta cagctgctaa gtggggacac aaagcagttg ctatcaccga ccacgggaat
    25381 gttcaatcct tcccacacgg ctataaggcg gctaagaaag cgggaatcca gctaatctat
    25441 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagagg
    25501 gacttgtcag aagcgaccta cgtggtcttt gacgtggaaa cgacgggtct atcagccatc
    25561 tataatgatt tgattcaggt tgcggcctct aagatgtaca aggggaatgt cattgctgaa
    25621 tttgatgaat ttatcaatcc tgggtatccc ttgtcagctt ttactactga gttgactgga
    25681 attacagatg atcacgtcaa aaatgccaaa ccactagaac aagttctgca agaattccaa
    25741 gaattctgca aggatacggt cctagttgcc cacaatgcga cctttgacgt tggctttatg
    25801 aatgccaact atgagcgtca tggtcttcct aaaattagcc agccagttat tgatacgctg
    25861 gagtttgcta gaaacctcta tcctgagtat aaacgtcatg gtttggggcc tttgactaag
    25921 cgttttggtg tggctttgga acatcaccac atggccaatt acgatgcgga agctactggt
    25981 cgtctgctct ttatttttat caaagaagta gcagaaaaac atggagtgac cgatctagct
    26041 agactcaaca ttgatttgat tagtccagat tcttataaaa aagctcggat caagcatgcg
    26101 actatttatg tcaagaatca ggtaggtcta aaaaatatct ttaagctagt ttctttgtcc
    26161 aatactaagt actttgaagg ggtgccacga attccgagaa cagttctaga tgcccatcgg
    26221 gaaggtttga ttttaggttc agcttgctct gaaggtgaag tttttgatgc ggttgtttcc
    26281 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    26341 ccagctatct atgctccctt gattgccaag gagcaggtca aggatatgga agaactccag
    26401 actattatca agaatttgat agagatcggc gaccgtcttg gcaagcccgt tttggctacg
    26461 ggaaatgtcc actatatcga accagaagaa gaaatttacc gtgaaattat cgtccgcagt
    26521 ttgggtcagg gggcgatgat taaccgaacc atcggtcatg gtgaacatgc ccaaccagca
    26581 ccacttccaa aggctcattt tagaacgact aatgagatgt tggatgaatt tgccttcttg
    26641 ggagaggaac tagcccggaa attggttatt gaaaacacca atgccttggc agaaatcttt
    26701 gaacccgttg aggtagttaa gggtgacttg tatacgcctt tcattgacaa ggctgaagaa
    26761 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gttgccagat
    26821 attgttgatt tgcgaattga aaaagaattg acttccattc tggggaatgg atttgctgtg
    26881 atttatctgg catcgcagat gctggttcaa cgttccaatg aacggggtta cctggtgggt
    26941 tctcgtgggt ctgtaggatc tagtttcgtt gcgactatga ttggtattac ggaggttaat
    27001 cctctctctc ctcactatgt ctgtggtcag tgtcaataca gcgagtttat caccgatggt
    27061 tcttatggtt caggttttga tatgcccaat aaggactgtc caaactgcgg tcacaaactc
    27121 agtaaaaacg gacaggatat tccgtttgag accttccttg gctttgatgg ggataaggtt
    27181 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    27241 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    27301 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    27361 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    27421 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    27481 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    27541 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    27601 caggatttgt ctggtattga ccctaatgaa attcctatgg atgacgaagg cgtgatggca
    27661 ctcttttctg ggactgatgt gctaggggta acacctgaac aaattggaac gcctacgggt
    27721 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    27781 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    27841 ttggggaatg ctcaggatct gattaagcaa ggaatagcgg acctatcgac tgttatcggt
    27901 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggccttt
    27961 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    28021 gactatatcg aagccatgaa ggccaataag gtgccagagt ggtatatcga atcctgtggg
    28081 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    28141 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    28201 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    28261 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    28321 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg caaattagat
    28381 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    28441 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    28501 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    28561 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    28621 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    28681 aatagattta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    28741 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    28801 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    28861 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    28921 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    28981 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    29041 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    29101 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    29161 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    29221 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    29281 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    29341 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    29401 gtgctattgc tttagcagga atcttttctg ctttgagaga aaaataaaaa tagaaaagag
    29461 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    29521 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctttctatt gatgtggagc
    29581 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    29641 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    29701 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatctcttg gagaacaagg
    29761 ctagccgtct tggagttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    29821 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gcctatgcgt atcgcaactc
    29881 aatctaacaa ggttagctgg actgtagcag ctgcagcagg acttgagtgg gctaagaaag
    29941 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggac caaattttca
    30001 aaacttgccg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    30061 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    30121 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    30181 tcaatgcaca gggcgaagaa ttcttgccaa atatgccaac agaagaggtc ttcacagcgc
    30241 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    30301 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    30361 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    30421 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt accttcttta
    30481 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    30541 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    30601 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    30661 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    30721 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    30781 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    30841 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    30901 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    30961 ct
//
LOCUS       DAVBOM010000025        30096 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBOM010000025 DAVBOM010000000
VERSION     DAVBOM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.025"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..85)
                     /locus_tag="VQ878_001171"
     CDS             complement(<1..85)
                     /locus_tag="VQ878_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3095513.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEM"
     gene            complement(93..533)
                     /locus_tag="VQ878_001172"
     CDS             complement(93..533)
                     /locus_tag="VQ878_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3095514.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETRQAKPDEIRLPAKQNMV"
     gene            complement(535..1572)
                     /locus_tag="VQ878_001173"
     CDS             complement(535..1572)
                     /locus_tag="VQ878_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET3095515.1"
                     /translation="MNQTVEYIKELTAIASPTGLTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1670..2995)
                     /gene="brnQ"
                     /locus_tag="VQ878_001174"
     CDS             complement(1670..2995)
                     /gene="brnQ"
                     /locus_tag="VQ878_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET3095516.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVIGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3166..3258)
                     /locus_tag="VQ878_001175"
     CDS             complement(3166..3258)
                     /locus_tag="VQ878_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3095517.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(3301..3453)
                     /locus_tag="VQ878_001176"
     CDS             complement(3301..3453)
                     /locus_tag="VQ878_001176"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3095518.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(3613..4191)
                     /locus_tag="VQ878_001177"
     CDS             complement(3613..4191)
                     /locus_tag="VQ878_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET3095519.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4245..5645)
                     /gene="pepV"
                     /locus_tag="VQ878_001178"
     CDS             complement(4245..5645)
                     /gene="pepV"
                     /locus_tag="VQ878_001178"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET3095520.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5658..6263)
                     /locus_tag="VQ878_001179"
     CDS             complement(5658..6263)
                     /locus_tag="VQ878_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET3095521.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6434..7234
                     /locus_tag="VQ878_001180"
     CDS             6434..7234
                     /locus_tag="VQ878_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3095522.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7416..8213)
                     /locus_tag="VQ878_001181"
     CDS             complement(7416..8213)
                     /locus_tag="VQ878_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3095523.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLDAETDVAVYGHVHKQLLRYGS
                     QGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKVAYDYEAELELAK
                     SKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(8203..10047)
                     /gene="uvrC"
                     /locus_tag="VQ878_001182"
     CDS             complement(8203..10047)
                     /gene="uvrC"
                     /locus_tag="VQ878_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET3095524.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(10087..10788)
                     /locus_tag="VQ878_001183"
     CDS             complement(10087..10788)
                     /locus_tag="VQ878_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET3095525.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(10867..12099)
                     /gene="murN"
                     /locus_tag="VQ878_001184"
     CDS             complement(10867..12099)
                     /gene="murN"
                     /locus_tag="VQ878_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET3095526.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12104..13324)
                     /gene="murM"
                     /locus_tag="VQ878_001185"
     CDS             complement(12104..13324)
                     /gene="murM"
                     /locus_tag="VQ878_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET3095527.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13436..14215)
                     /locus_tag="VQ878_001186"
     CDS             complement(13436..14215)
                     /locus_tag="VQ878_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3095528.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14284..15945)
                     /locus_tag="VQ878_001187"
     CDS             complement(14284..15945)
                     /locus_tag="VQ878_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3095529.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILHESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16120..18342)
                     /gene="recJ"
                     /locus_tag="VQ878_001188"
     CDS             complement(16120..18342)
                     /gene="recJ"
                     /locus_tag="VQ878_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET3095530.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18619..19377
                     /locus_tag="VQ878_001189"
     CDS             18619..19377
                     /locus_tag="VQ878_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3095531.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     LDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            19388..20182
                     /locus_tag="VQ878_001190"
     CDS             19388..20182
                     /locus_tag="VQ878_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3095532.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20195..20872
                     /locus_tag="VQ878_001191"
     CDS             20195..20872
                     /locus_tag="VQ878_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3095533.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            20882..21541
                     /locus_tag="VQ878_001192"
     CDS             20882..21541
                     /locus_tag="VQ878_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3095534.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            21778..22902
                     /locus_tag="VQ878_001193"
     CDS             21778..22902
                     /locus_tag="VQ878_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET3095535.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(23300..24181)
                     /locus_tag="VQ878_001194"
     CDS             complement(23300..24181)
                     /locus_tag="VQ878_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET3095536.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24322..25650)
                     /gene="vncS"
                     /locus_tag="VQ878_001195"
     CDS             complement(24322..25650)
                     /gene="vncS"
                     /locus_tag="VQ878_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET3095537.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(25647..26303)
                     /gene="vncR"
                     /locus_tag="VQ878_001196"
     CDS             complement(25647..26303)
                     /gene="vncR"
                     /locus_tag="VQ878_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET3095538.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26352..26435)
                     /gene="pep27"
                     /locus_tag="VQ878_001197"
     CDS             complement(26352..26435)
                     /gene="pep27"
                     /locus_tag="VQ878_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET3095539.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(26616..27995)
                     /gene="vex3"
                     /locus_tag="VQ878_001198"
     CDS             complement(26616..27995)
                     /gene="vex3"
                     /locus_tag="VQ878_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET3095540.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTAHAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(28047..28694)
                     /gene="vex2"
                     /locus_tag="VQ878_001199"
     CDS             complement(28047..28694)
                     /gene="vex2"
                     /locus_tag="VQ878_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET3095541.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(28707..29984)
                     /locus_tag="VQ878_001200"
     CDS             complement(28707..29984)
                     /locus_tag="VQ878_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095542.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         8607 a         6921 c         5592 g         8976 t
ORIGIN      
        1 acatctcttc aaaagtggta cgctgaacac caacaagacg cttaaatcgt gcatcagtta
       61 gttgtttact tgcttcatca ttcatagaac tactatacca tattttgttt cgcaggaagt
      121 ctgatctcat ccggttttgc ttgacgggtt tctgcggtca tttcttcaaa agggacccac
      181 cagactggcc cacgtccatt gagaccgtga ccattcatgt cacctgttcg tctaggaaac
      241 agatgccaat gaagatgggc atcgccattt cctagcagtt cgatattcat tttctcagca
      301 gcaaaggcct tggcaactgc ctcttggacc acactcattt cttctagaaa acggagtctt
      361 gtctcctttt tcaaatggtg caattccgtg acatgttcct tggctagaaa gagactatag
      421 cctgcaaaat actgatggtc tccaatcaca agatagcctg tttccaactc tttgacaaag
      481 tagggatttt ctcccttctt gatgagctca attctctggc aaataaggca catatcaatc
      541 tactaaattg cttctaagat aggcatcgac cattcgttct gttgcgacca ccgagtcaat
      601 atgagtgcgc tcataagaat gactagactc gatacccgca ccaagaaggg catgcttgac
      661 ctctgcccct gcagacatag ccgctgaagc atccgaacca taaaatggat agatgtccag
      721 cttaaaagga atatcttgct ctttagccaa ggcaaccaag tgttgacgga agtcatagtg
      781 ataaggacct gaagcatcct tgacacagat agatactgtg tactcatctg tctgctggtc
      841 atctcccata gctcccatat ccacagccag atattctact acctgagcag gaatgttaga
      901 attagcacca tgtcctactt cttcaaaaac tgaaaaagca aaatgagttg ttactggcaa
      961 ttcaatcttc tctttcttat aaatacgaag caggttgagc aaaatcgctg cgctgacctt
     1021 atcatccaaa tgacgagact tgataaaacc tgtatcagtc acaacagttc gtggatcgaa
     1081 gctgataaaa tcaccgacct caatcccaag agcacgagtt tctttttcat tgcttacttt
     1141 tacatccaaa cgcacttcca tattgtcctg cgtgcgttct gcagttcctg catccttgta
     1201 gacatggcaa gaagtttggt ggatgaggat ggttcctgat accttttgac ctgtgctagc
     1261 cacatgaacg gtacagtttt caccttcaat catgttccaa ggaaaaccac cgatacggtc
     1321 caatttaaga cgaccatctg gtttgacagc acgaacaata gcacccagcg tgtccacatg
     1381 ggcagtcaca tagcgatgtt gctcatcatt ttgacctttg atggtcacat tgacaccacc
     1441 cttggctgtg cgaactggct ggtaaccaaa accttctaga gtcttgacta aataattcga
     1501 aatttcacga gttaagcccg ttggcgatgc gatggctgtc agttctttga tatattctac
     1561 tgtttgattc atttcttcac ctctttcgct acctattata acacatttat catcggataa
     1621 aaaaagaaaa tcactcctgt agacttggct acaaaagtga tttaagtgat tattccattt
     1681 caaaaacatc gctttcttgc ttgtttggta gaaccaatga gagcaagatt ccaacaatgg
     1741 ctggcaccaa ccatgggaga gatgccttgg caaaaggaag aacgctaaca agatttgcaa
     1801 gaaactcaac cttaaacgag cttcctagta cgcttgcaat ggcaataact gtaaccacag
     1861 caattgtcaa ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca atgacaatca
     1921 taacgatagc aatcgtgatt gggtacaaga taaccagtac tggaattgag tacttgataa
     1981 tcgcatcaag acccaaattg gcaatagcaa atccaatcaa ggtaaaggct gtcgcataaa
     2041 ccttgtagct gatttgtggg aagcgctcat taaagaactc agctgttgac acaatcaaac
     2101 caacagtcgt tgtgaagcag gttacggtaa ccatagctgc aaggaagagt tgagctgttg
     2161 agccaaagat ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt ccacccttca
     2221 tcgcttcagc tggtactggg aaatgatttc caagaaaacc taaaccaatg taaagagcgc
     2281 tgaaggcaag ggcaacaacg ataccaataa cccaaatagt tgaaatgtat tctttcttac
     2341 ttgaaaatcc aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc actgaggcaa
     2401 gggcgtccaa ggtattgtaa ccttctagga aacctgtacc aaaggcagaa gcttgataag
     2461 cagctgaagc agcttgagga cttgttccac catatttgat agctcccaga acgaccaaga
     2521 taacaatcaa aattgcaaag actggcgtta aaatacgtcc aatgcggtct aagatttttg
     2581 atggattaag cgaaatcaaa taggctgccg caaaatacag aaccgtaaat acaatcaagc
     2641 caagtccttt atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa gctgttgtag
     2701 cagtacgtgg ggtagcaaag aatggaccga ttgacaagta aagaactgag aggtaaagag
     2761 tcgcaaacca aggcgctatc ttcgttgaaa tctcgtagat atatccttta ggatttagcg
     2821 ttccaataat aagggtcaag acggcgatac caacgcctga aaagacaaaa cctgcgatgg
     2881 caggaagaaa atgttctcca gatagagcac ctagagaagg cggaaaaatc aagttccccg
     2941 caccaaaaaa tattccaaac aggagcaaac ctgttagggt acctttttta gccataaaaa
     3001 tctccttcat atttataaaa tactgaccta gtataccacg attaggagtc tgaaaaaagc
     3061 atcacgaggc aaatattaaa tgttttcaat tttcttaaaa ataagaatta tctaaaaata
     3121 aaactctcct acccagtcca caccaagtag gagaaatgca aaattttaaa gttcttcaaa
     3181 ggctaacatg ccaccctgga cattgataac attataacct tgttctaaca ggaattggca
     3241 agcacgcgcc gatctcattc cagatttgca aataatataa tgcaagcgat ctttgtccaa
     3301 ttaatcataa ctatcagcca attgactaag cggtaggttg tgggcacatt ctaaatgaag
     3361 agctgcaaac tcatccactt ctctcacatc cactagagaa agctggtcgt tttggtaaag
     3421 ctggtaaaat gcgtcaaagg ctatttcttt cattcttttt cttctaatac tcttcgaaaa
     3481 tctcttcaaa ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt cgtcagtttt
     3541 atctgcaacc tcaaagctgt actttgagca gcctacgact agcttcctag tttgctcttt
     3601 gattttcatt gactataaaa tggttttaat tctttttttc aaatctggca ctacttctgc
     3661 ctcaaaccaa ggatttttgg ccatccagat ttgatttcgt ggtgatgggt gaactagcgg
     3721 aaaataggct ggcagatagt ctttatagtg tttcaccctc tccgttacct tcccactgat
     3781 tttctcctgt aaatagtagg cttgggcata ttgcccaatc aagagggtta actgaatatc
     3841 aggcaattcc tgtaagagct gcggatgcca tttttctgca aaacctgtac gaggcggaag
     3901 atcacccgac ttgccatgtc ctggaaagta gaaatccata ggcaaaacag caaaataacc
     3961 tgaattgtaa aaggtatctt catccacacc tagccagtcc cgcaagcggt caccactttt
     4021 atctttccag taaaggcctg cttcttgagt tttaagtccc ggagcctgac cgatgatatt
     4081 gatgcgagca gtttttggcg ctgcaaagag aggctcaatg ccacgctctg tatagctggc
     4141 attctgtgaa tccgccatga tagcctgttt gattctttcg atttgagaca tctactttcc
     4201 ctccaaaaag aagtccaagc ataagatctc agacttctat cgttttattt gatcaattcg
     4261 taaatagctt cggcataaat tgctgctgct cggaaaagat catccaaggc gataaattca
     4321 ttggcttggt gcatggtatc aatcgagtct gggaacatag caccgtaggc aactccgcgt
     4381 tctagcaagc gaccaaaggt tccaccaccg atgacttgtt catgaccttt aaggccagtt
     4441 tgtttttcat agatattcaa caaggtttgc acaagtggat cttccattgg cacatagtga
     4501 ggcgtgtgac cgtgttcaga caggctaaca gaaacaactg gcaagttttc aaggattgac
     4561 ttgatttgtt ctggacttgt tccttttgga tagcggatgt tgagggcaat ggtattatca
     4621 gcacttgttt catcgaagcg gaagacgccg gcattcatag aaagagcacc catcttttca
     4681 tccacatgag caatcttaag attttcaccc tcatgatcgt tcaagagaat tttacctgcg
     4741 atgtcaaggt agtctttggc tggaccagca aagccaaact ggctgaggaa gagggcaagg
     4801 taagttgcgc cattgacacc tgaagcaggc atagcaccgt gggctgattt accaatgatc
     4861 gtcaccttgt atttgccagc ttcttcttgg agttctcctc taagtttgtg ttctgcaaca
     4921 aaggcatcta gtttagcttg caagtcagcc aaatcacctg aaacgactgc tgttgctgat
     4981 tctggtacca tattttcacg taaaccacct gtaaagctgt gaagacgggc agcacctgta
     5041 ttttctcctg caaagtggag gtattccgtg atatttcctt tttcaccatt gatgattgga
     5101 aattcagcat ctggagagaa accgaaatct ggtttggcaa gtcctacgtg ctcaaagtag
     5161 tagtccatgt ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg aactttctta
     5221 gaagttggaa gacccaattc tttgatgatt ttcaaaccat agtaacaagc tgttgtagga
     5281 cccttatcgt ccgaagcccc gcgcgcataa aggcgaccat ctttgatagt tggtgtgtaa
     5341 ggatctgtgt cccaaccgct accagcaggc accacatcca tatgggcaaa gattccgaga
     5401 acttcttctc catcaccaaa ctcaaaatgt cctgcgtagt tatcgacatt cttagttggg
     5461 tagccatcgc ggtctgcgat ttcaaggaat ttctccaagg cttttactgg accaggtcca
     5521 aatggatgct gggcatcagc cttgctatca tcacgttctg agttgatttc caaaaggcta
     5581 aacaagtcag ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa atcaattgct
     5641 gtcatttttt cttctttcta tcttttctcg atgatttcat ctactggcaa gcggtagctt
     5701 ggttccaatt tgtcgtctgt gtaacccact gtgatcaaga gttctgggcg gaaacggtct
     5761 tcgatttcca aaacttcatt aacttttgat ttgtcaaaac caaggataat attggaacca
     5821 attccttggt ctgtaagagc gagaaccaag ttcatagcaa ccaaacctgc attgagtgct
     5881 aggtagtcgc tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa atttttcatg
     5941 aagtattgaa gttgctcttc agaaaagtta ttagcaccac caacacgggc aatcttacga
     6001 gcacgtttgg ctaagtccgt atctgtaaac aaggcaatgg ttacaggcgc tgatgatacc
     6061 tgttcaaaat tggaaccata agctaacttt gccagttcag catttttctc acgtaccacc
     6121 acaaatttcc aaggctggct gttgtgggcg cttggcgcca aggttgcaat ttcgatagcc
     6181 gtacgcacat cttttggatc aacaggctta tcagtaaaat gcttagtcgc atgacgtttt
     6241 ttatttaatt caagaaattt cataatcgat ttccttttct aattctactg cttccattct
     6301 accataattt gaaagagctt gcagggattt ttcatgatta agtttttcta tcacagacat
     6361 aaaagatata tattggttta tcaggaacat ttctgataaa ctagcaagta ctttacattt
     6421 gaatggagac agtatgaaaa aatttagcct attactagct atcctaccat ttttggttgc
     6481 ctgtgggaat caagctacac ccaaagagac tagcgctcaa aagacaatcg tccttgctac
     6541 agctggcgac gtgccaccgt ttgactacga agacaagggc aatctgacag gcttcgatat
     6601 cgaagtttta aaggcagtag atgaaaaact cagcgactac gagattcaat tccaaagaac
     6661 cgcctgggag agcatcttcc caggacttga ttctggtcac tatcaggctg cggccaataa
     6721 cttgagttac acaaaagagc gtgctgaaaa atacctttac tcgcttccaa tttccaacaa
     6781 tcccctcgtc cttgtcagca acaagaaaaa tcctttgact tctcttgacc agatcgctgg
     6841 taaaacaaca caagaggata ccggaacttc taacgctcaa ttcatcaata actggaatca
     6901 gaaacacact gataatcccg ctacaattaa tttttctggt gaggatattg gtaaacgaat
     6961 cctagacctt gctaacggag agtttgattt cctagttttt gacaaggtat ccgttcaaaa
     7021 gattatcaag gaccgtggtt tagacctctc agtcgttgat ttaccttctg cagatagccc
     7081 cagcaattat atcattttct caagcgacca aaaagagttt aaagagcaat ttgataaagc
     7141 gctcaaagaa ctctatcaag acggaaccct tgaaaaactc agcaatacct atctaggtgg
     7201 ttcttacctc ccagatcaat ctcagttaca ataacactct tcgaaaatct cttcaaacca
     7261 cgtcagcttt atctgcaacc tcaaagctgt gctttgagca acctacggct agcttcctag
     7321 tttgctcttt gattttcatt gagtataaga tatactaaaa gcgattggac cagccaatcg
     7381 cttttttagt ttgcattggc tattttagga aactcttaca aaaaatcaaa aaaattcttc
     7441 acatcctcta catacccatg cttttctatt aagctggcta ataattccag attgtgcccc
     7501 tgatagttat cgtcacgacg cagttcttca tacatttcga taaagggaag ccccttggac
     7561 ttggccaatt ctaactcagc ttcgtaatca taagcaactt tacgaaattg gatattgagt
     7621 aattccccat cttcaacttc tatcacggca tactgggcac ggtgattttt taacgcctcc
     7681 caattaaaat agggcatgcc aatcgaccct ggattgatga tttgttgccc ttgacttcca
     7741 taacgaagca actgcttgtg aacatgacca taaactgcca cgtccgtttc cgcatctagc
     7801 aagtcaccac catagttttt gtcaggtaaa ttatgagaga tagaaaagcg caatccgtca
     7861 atttctttct tttccagcaa aggcaagctt cgtagccaga caatcgttgc aggatccatt
     7921 cgctccatca aatactgtgt catacgcaag agctgaactt cctgtgggtc ttctaagcca
     7981 tattgcccat ctaaagcctc aaggacacga tcatcccaat tgcctcgaac acttgctgtg
     8041 ataggaaggt cctttagcag ggcgactaag tcatttgcgc ctggaccagg aagaaaaata
     8101 tctcccagaa gccaatattc actggcccct tgatttttag catctgcaat cactgcttct
     8161 agcgccgtcg cattgccatg aacatctgat aaaattgcga ttttatggtt cattgtggtt
     8221 tccttccgtt tggtaatcta ctctttcttc tgctacttga ggcaaggctt ctccctgcgg
     8281 gttcaacttt ctttgcacag cctctgcaac gactctaggt accccaactt cgacaatctc
     8341 atccacactg gcttccttga ttttggtcaa agacttgaaa tgcctcatga gattttgctt
     8401 gcgtttaggt cccagaccat caatcccatc caattgagat gagaaagaat ttttggagcg
     8461 cagttggcgg tggaaagtga tagcaaagcg gtgcacctca tcttggatgc gttggaggag
     8521 gaaaaattcc tgagaattgc gagacaagtc caccacctca agcggatctc caaagagcaa
     8581 ttcatgggtt tggtgcttat cattcttttg cagcccagca attggaatat ccaagcccag
     8641 ttcctcttgg ataacctgct tagcgatatt gacttgacct tgccccccat caatcacaat
     8701 caaatctgga ggagtcaaag cctcacgctg tactcgacca tagcgtctgc gaatgacctc
     8761 tctcatgctg gcatagtcgt ctggtccaac aaccgttttt atcttgtact tacggtaatc
     8821 cttcttactc ggtttaccgt tgacaaagac caccatagcc gaaacagggc tagttcccat
     8881 gatattagag ttatcgaagg actcgatacg tactggggtc gggatttgga gcaaacgccc
     8941 tagattttca atagctcctt gagtcttttc gacagatttt tctagcagat tgaacttctg
     9001 ctctagacta acacgagcat tttttatggc tagattgacc agttgttttt tctctccacg
     9061 ttgaggctta agaatcttgg aatccaccaa ggccttgaca gcctcttcgt caatatcctg
     9121 cggaatcagt acctcattgg gaactagatg agatttttct tgatagaatt gtcctacata
     9181 ggtcaaaaaa tcctcatctg gatcattgaa gtaggggaag agattgacat cgcgctcgat
     9241 aagcttaccc tgacggacaa agaaaacctg cacacacatc cagcccttat ccacatagta
     9301 gccaaagaca tcgcgatttt gcaaatcttt cgccatgacc cgttgcttgg ttcgaagcgt
     9361 tccaatagcc tgaatcaggt cacggtattc cgccgcacgt tcaaactcca tactttgtgc
     9421 tgctactgcc attttactct tgagatcatc gatgattttg tcatcctgac ctttcagaaa
     9481 atcagacacc tcctgagcca tagacttgaa ataagcctca tccttcttac agatggtgtg
     9541 ggccatacac tggccgatat ggtaataaaa acagacctta gagggcgggt tggtacattt
     9601 tcgaaaaggg aaaatcctat ctagaagtcg cttgatttca ttggctgccc ccacatctgg
     9661 ataagggcca aaataaagac caccgtcctt tttgacctga cgagtaatga taagccgtgg
     9721 atagcgctca ttggtgattt tgatgaaagg ataggacttg tcatccttga gcatgatatt
     9781 gtacttgggc ttgttttcct tgatcaggtt gatttctagg agaagtgcct caatattaga
     9841 ctccgtaaca ataaattcaa aatccacaat ttcagacacc agagcctctg tcttggtatc
     9901 atgacttcca cgaaaatagg accgtactcg attacgcaga tttttagcct ttcctacata
     9961 gataatggtg ccatttttat ccttatgaat gtagcaacca gggctggtcg gcaagagctc
    10021 tagttttgat ttaatcaagt tgttcatagt tccattatag caaaaaaagt agggaaagat
    10081 agtaccctac tcactagtct catatatttt tcggaggttt gcaacatcct cttcctggat
    10141 accataaaag gaacctgctg gttgcatgac agacttctca tctgtatggt ccaagccaat
    10201 cgcatgacct aactcatgtt ctgccgtatg gacaaggcgt tcataggagt agccatagta
    10261 tggattggac aaataataat gattcaaccg caccgttacg gacaagaatt gccctgttaa
    10321 gagattagtt tgactttccg cctctcctgc cacaggagtg cctccgtcgt tcatctccgt
    10381 agccgtaata tccgccttac tagactcagt cacgagttca aagttaaaag caccagtttg
    10441 attccagttc tggattgctt ctaaataagc ctcttgaaag cgtgaatcca tctgcggatc
    10501 caggtaaata cgagcagagg cctgtgccca ccttccttca gaatgctggt gactatctgt
    10561 ctggcttaac ttaggcagtt gccctgtttt ctcccattgg tcaatacttt gttgaccaat
    10621 ttttactgac cgttctgctt gctttagcgc tccttgaaaa tccccgttca gataccagag
    10681 aagtccgaaa gcaagcacac ataagagcac aactatccaa accagacgcc aaaacaaacg
    10741 ccacacaaaa gaaaagaaag cccctatcaa acgaaaaagc cagcgcatgt ctctccacct
    10801 ttctagcaaa taagaattat tttactaaaa gaagctaaaa gaaatctaaa tactgacttt
    10861 ttcatcttaa cgtcctacta tttttttgag taactggata gctttgtatt ttaaaggcga
    10921 tggatggtaa cggaaagtac ccgctttgcg tacaatatag ccattaaaat tctgtttaaa
    10981 acgcaaaaca ccatcacttc catcaaaaat cccttgaatg cctaggaagt tgtatttagg
    11041 tattccacgt tttatgcttt ccaacataac atatttttga agcagggcag gggcatagaa
    11101 cttattaaac tcagtgtagg aaccactaaa gagataagtc gtttcctgag gcatataaac
    11161 aaataaactc ccagctaaaa caatatcttc ttctccatat ttttcaatca agtctcgcgc
    11221 ttctgctttt cgaacttcaa acgtttcaaa ttgactagaa tattctctca gttgattttg
    11281 ttttttctca gaatgaggat ttttactcaa atcaagtcgc aacttgtcca agttttcttc
    11341 tagtttactt tgttcacctt gcaatttgct catatagtcc gaaaaattta agcttgctat
    11401 gagaaactcc gcttgttctc caaaagtatc ataaaaatgc tcataatatt ctaaactttt
    11461 atcactatat tctctacgtt cagaggtttc ttttgttata ttcttaaaaa tcgatagttc
    11521 ttcacgtttt aactttttca accgaatgcc aaaggtttca gcctttttca ccaagggttt
    11581 accctttttg ctaaaacttt taagcaaact cttttcagtt aattcagtta aatctttata
    11641 gtataaccaa tctggttctc cacctgggta acctgttgtt aagccatcaa attgataacc
    11701 taaatcagtc aaaccttgaa taatactttt tttctcagca tctattggat taccttggct
    11761 atcaaaagtt tgataagttt cataaggttt tacaagcaac tctaatacac cattttgctt
    11821 ggcatattct tttaactctg cataaaaaac tggaagagca tcttgttggg tataaatcgg
    11881 ccccgaattg agttccatat gcagaccacc cagcatgggc aagctataaa ccagagctgc
    11941 aacttgaatt tctccttctt gtttcaaagc aagataaaca attcgagccc ctcttttttc
    12001 tagcaaatcc cccatctgga cagattgcat aaaggaacga gaagaaacct gatcagaata
    12061 agtctgaaac tcttctttcg tgagtgttgt tagtgccata tacttacttt ctatgttttt
    12121 ttcttaatgt tttacggaaa tcaagagcaa gtcttaacag aggatagaga ggatgagtgg
    12181 gcattgtaaa ttcacccaag tattcttcaa tcgttggatt aaatttttcc ttaaaatgat
    12241 aaagtccacc attgagagag ttttcaacac cacctaaatt ttgccaaacc atacctcgct
    12301 caaaggcata gcgagccgtt tcataccatg ttaaaattgg tgcattgtaa cgtttaaaat
    12361 catcatccat accagcatat atattgacag aggtagtacc aaattccaaa ctcaaagtag
    12421 ccgctaaagg aactctcgct tgacctacat ctatatattc ctgcaagaag gtcaattcct
    12481 ctaacaaacg ttctttttcc ttcttctgcg cttctacttt tgaaattcga gtcgactcag
    12541 taaaggtctc ttccaaggct ctattttttg ctaactgttc ttctaattct tgcgaacgtt
    12601 tagaaacatc caaggtggcc aaggtgatat aggccttgtc cttaaaatta tctaacaatt
    12661 ttttataata ggcttcattc ctcaaatgaa tctcttttcg cttctcagtt tttttcatca
    12721 actccgaaaa tgaatctaat agttccagtc caccatattg aatctcaagc cctttgtttc
    12781 gtgctgttcg aatagcctgt tttgttgact tggaaagttt atcttcttca aaattttcct
    12841 tgtatatttt cgcctgaata cgaggttgaa tggtgtctcc catttcctcc gtttttcctg
    12901 accaccttac tcccatttgt tgcaaactat caataatagc cagattttca ggaaattctg
    12961 tcttttcctg attgattaaa ctttgagata ggcaaatact tgggtcaaaa gtcacaaaaa
    13021 ccgctctctt actgcgagca taggacttaa tagactgaat gacaaaattc aagagttctt
    13081 tatccccata atccaatata ggtcctcttg ggatgtaaaa cattttatag cctagcggaa
    13141 gagttctaat caaaatacta gctgtcgcca gtaatttttc ttccctgtaa acaccaaact
    13201 tctcatgttg ccaattagac ttaacttcct cccaagcact actttgtaat acattggcta
    13261 attcatgttc tttgacaaac tgatcatatt ctaatgtggg aatgccaatt tgataacggt
    13321 acatttccta ctctctttcc tccagtattt tattactatt ctactacttt cgtttgaaaa
    13381 gtctagtgaa aacatatttt attttagttc tactccccct atgctgaagt tcaaactaag
    13441 tcagtctctc ttctaatttg aaatcaattg gtagggttgt taaaaaaact tccaattgtt
    13501 tttcccagta gtaccactcg tgagttccag cgctatggct ataggtcaca tcaaaaccta
    13561 gttttttgag atttttcact gcgagattat tggcttcgta caagaaatcc tgttcgccac
    13621 accacgccca aagtttggtc tttttatccg attttttagc cagactttca agagaatagg
    13681 gactagttgt ccagtcttta atctctccaa aaacacctct ccagtaggct ggacttccca
    13741 gattttgact ttcaggagaa aagttttgaa aactgagggc acctgaaaag ctagctgcat
    13801 gagaaaaacg atttgtcgca agagccagtt tgaagcagcc gtagcctccc atagaaagac
    13861 cagcgataaa ggtcttttca cgcttgctag tcatattagg gaagaagcgt ttcagaacct
    13921 gtggcaattc ctctgctaga gccgtgtagt agtcaaaacc atactgggta tcggtgtacc
    13981 aaccattgct ggtattgggc ataacaacga tgagattagt tcctcgaagc aagcgttcta
    14041 cattggtccg cttaagccaa ctattatgat ttccagacat cccgtgcaaa aggtacaaga
    14101 cgggaatatc ttcacactct ggttcttcca ctcgattggc atcagggtag aggacattca
    14161 ccccccactc catatccaat acttgtgagt aatactcgat tttcattact gccatgattt
    14221 tctccttcta tttttctata agaaaaagcc gaaactcgac tttctctctg tttatttcaa
    14281 cgattatttt gcttccatga ctactggtaa aatagctgga cgacgcttgg tttggtcaaa
    14341 gagatacttg gtcaaattat ctcgaacctt ccctttaaga tctgcccagt caaagtcatc
    14401 tccttgaaga tactcttcta ccgtttggtt aatcaattct gaactttcat ggagaatatc
    14461 gcgactcttc ttgagataaa caaatccgcg cgtatgaaca cgagccctag ccacaatttt
    14521 cttctcacga cggttgactg taatagccac gatgaaaatt ccatcctctg acaagacctt
    14581 acggtcacga agaacaacat ttccaacatc accaatggca ttcccatcaa tcaagatatc
    14641 tcctgctgaa accgatccag ctggaacaaa gtctccattc tcgtaagcca tggtcgtccc
    14701 ctttttagga atgaagatgt gttctggcaa catcccaact gccatggcag ccttagcgtg
    14761 agcatccaac tcacgatact ccccttggac agggaagagg tacttaggtt gcaaaagatt
    14821 gatcatcagc tgcaaatcac gcacatttcc gtgccctgat acatgtaaac tttgggtaat
    14881 caatttgaca accccacctg cctgataaat catattttcc acacgcgcaa caaaggcttc
    14941 tttagcaata gacggagccg tagcaatata gaccaggtcc ccatccttga tttctacata
    15001 acgatggcga ccaatcgaca tcttacgaag tccattgata ggttcaccca tacgacctgt
    15061 ctcaagaata atcaactcat ggtcttcaaa gcgagacata tctttaggct taatcaagag
    15121 aatttcgttg gctaaagaca acttcttaag acgaatcgct gtgcggacga tattttcaat
    15181 atcaaatcct gtcaagacga tacgtcgacc tgttttatcc gcagcgtcaa aaatctgctg
    15241 aatacgagaa agattactgg aaacagctgc aacgatgata cgaccttccc agtcagcaat
    15301 agtttgggta atttcatccc taacttcact ttcactagcc acctgaatat tgctgtctgc
    15361 attggccgaa tcactgagga gagccaggac gccgtcacga ccaatctctg ccaaacgagc
    15421 aaaatcagtt gcataagatt cactagccgt ttggtcaaat ttgaaatcac ctgtataaac
    15481 gatgcttcct tccgatgtct tcaagacaat tcccagactc tctggaacgg agtaagtcgt
    15541 agggaagaag gaaaccactg tcccaccaaa atcaatctcc gtattctcat caatgacatg
    15601 gaaatcatta aatttcttaa cggcatcatt tcctttgaca aagagctttg ccaactcaat
    15661 ggtcaactca gacccaaata caggaacttt agcctctgcc aagagataag gtagagcacc
    15721 aatggcatcc gcatgcccgt gggtcaagaa aaccccagca atacggtcgc tattttcaaa
    15781 aaggtaatcc atgtttggaa tcaccacatc gacccctaat tgttcatttt caggatattt
    15841 taaccctaca ttcaaaacaa aaatggactc tccaatttca gcaatgtaca tattttttcc
    15901 attctcacgc acaccaccaa gtgttgttaa actgatatta ctcatttttc ctccaaaatc
    15961 ttagtttatc ttgattatag ggcaactcta ccctcttatt ctaaaagttc taatactttc
    16021 agccgaatct tttcctacca ttataccatt tttttgatga ttttcaaaat gaaggtctgt
    16081 tttcaaaaaa gagttgattt cccaactctt tcctaacttc tactcttttt ccatcaaaaa
    16141 atcataaatt tcttgcaccg tacccagcgc catcatttct tggtctttaa cggtttgttt
    16201 gagattttgg taaatttgac tttctcctat ctcccgcttt ggcgcctctt tattgactgt
    16261 catcacacca tcttttatcg tcacaaagcc tagttcttca aatacttgaa tcatcttgac
    16321 cagcaagatt tgttgaatat taagatatgc agccaaatct ttcagcttgt agcgaatatc
    16381 aaactctggg aactggtaaa tagtcttgta caatttggca aactgatctc tagtcccata
    16441 acctgtcaga taataggcct tgtcaatatc atttttgaaa tagacagcag agaaatgctg
    16501 ttcctgaaaa atggtcttca gctgagtaat atcctctgga atgtttttta cgacaatagc
    16561 ttcactagcc gcaagatttg gcagttctcc aggaaaatcc aagactggaa caccttctgg
    16621 caagactgca ttttttccac gaatgttaaa aagttgaaca ccttccactc gcgcatccac
    16681 catcatcaac tggagggcag tttggccatt ccattggttg acagacaatt taaccgctaa
    16741 ctctagattc ttggtttgag aaaactctgt cgcccatctg ccttgaccaa aggctaccac
    16801 ttcaaaactc gcctcaccct tggaaatttt cagctttaga tgggcattac ctgcccccat
    16861 agtacgagca ctttcgacct gaaaattctt gatataaaaa ataggtttct gattatccat
    16921 tccaaaagga gctaaacgtt caaaactttt gaccgtttcc aagctaagtg cctccaaatc
    16981 caactcttca tctaggttta acttattctt gccaccagca tctgcacctt tttcacgaac
    17041 ataatcttcc aaaacctgag ataaatctga gagttgctca acttccagcg tcatacccgc
    17101 tgcacctgca tgacctccaa aggcgatgaa gaggtctcga tggggatcca gagcttcaaa
    17161 aatatcgacc gcttccacac tacgagcact gcccttggca cgaccgtctt ctatattaag
    17221 aacaatgact gtctgtccca attcttccaa taaacgacca gccacgattc ctagaacccc
    17281 aggattccag ccttccttgg ccaagacctg aaccttcttc tcaggatcca ccatggtctt
    17341 ggcttcttca tagatagact gaacgatttc cttgcgctct tcgtttttct ggtgaatcat
    17401 aagggcaatc tcatgcgctt cctcatcatc aaatccagtc aacaaatcaa tggcaggatt
    17461 gggatcatcc aagcgaccca aggcattcaa acgaggagca atctggaaac caaccgtttc
    17521 ttctgttact tcgttggcag caatcccagc catgtccagc atttcttgca gaccaatgcg
    17581 ctgggtatga cccaacattt ccagaccata ttgaactaag atacgatttt catccgtcag
    17641 actcaccata tctgcaatag ttccaatagc gaccaaatca agcaattcca cttgcacttc
    17701 ttctaacagg gcacaagcca acttgaaagc aactccacaa ccagccaaat atttaaaagg
    17761 ataatccgca tctggatgtt caggatggac aatagcataa gcatctggca gggtttcagg
    17821 catggaatga tggtctgtca caatgacatc tactcccata gactgagcca atgcaatagc
    17881 ctcatgacca gcaaccccat tgtccaccgt cacaatcaag gaaattcctt cttgctcgat
    17941 aaagtattta taaacactag cattagggcc atagccatcg gtaaaacgat ttggcaggta
    18001 aactcggcac tccgcaccaa gttgttccaa actttccttc acaatagaag ccgaagtcat
    18061 gccatccgca tcatagtctc cataaacgag aatattttcc ccttcttcaa tagcctgacg
    18121 aatccgctcc actgccttgt ccatatcatg gagcagataa gcatcatgta agtcctccaa
    18181 ggaaggttct aaaaacttct tcagactttc ttggtcctga atccctctct caaacaataa
    18241 ccgagccacc tcaggaccca gtccagcctt cttggctatc tttgtaaaat ccgcatcttc
    18301 tacctgcagg gcaaactgcc attcataagt aggtgttatc aaaaagacat ccactctttc
    18361 taagaattct attgcttcat tataacatga tttagacgtt ttctctatcc agattgcttt
    18421 tttataacat tttatagtat attgaaacta gaatagtaca cctctactta taaaatattg
    18481 ttagaaatcg atttgactgt cccgatcgat ttgtcctttt cttatttcac tatagtgaat
    18541 tttttcagat acggtttgac aagaacattc ttttattgta gaattgtgtt ataaaatcta
    18601 acataaagga gatctctcat ggctttagta gaatttaaaa acgtcgaaaa atattacgga
    18661 gactaccacg cactccgcaa catcaatctc cgttttgaaa aaggacaagt tgttgtcctg
    18721 cttggacctt ctggctctgg gaagtccact cttatccgta cgatcaatgg tttagaggct
    18781 gttgacaaag gaagtctcct agtcaatggg caccaagttg ctggtgccag ccagaaagat
    18841 ttggtacctc ttcgcaagga agtcggcatg gtttttcaac attttaacct ttatccacac
    18901 aaaacggtgt tagaaaacgt gacacttgcg cccattaaag ttctaggaat tgataaaaaa
    18961 gaagctgaaa aaaccgccca aaaatatctg gaatttgtaa atatgtggga caagaaagat
    19021 tcctatcccg ccatactatc tggtggacaa aaacagcgga tcgccatcgc tcgtggtctt
    19081 gctatgcatc cggaactcct cctctttgat gaaccaacat ctgctcttga tcctgagact
    19141 atcggagatg ttctagcagt tatgcagaaa ctggcgcatg atgggatgaa catgatcatc
    19201 gttacccacg aaatgggctt tgctcgagag gttgcggacc gcattatctt tatggccgac
    19261 ggagaagttt tattagatac gacagatgtc gataactttt ttgacaatcc aagcaaacct
    19321 cgtgcccaac aattcctcag caaaattatc aaccacgaaa gtgacaaagt caaataagga
    19381 ggcgcctatg aaaaaaaaat tctttttatc agcattattg attagccttt tcggccttgc
    19441 tgctgccaaa ccagtccagg ctgatactag tatcgcagac attcaaaaaa gaggcgaact
    19501 ggttgtcggt gtcaaacaag acgttcccaa ttttggttac aaagatccca agaccggtac
    19561 ttattctggt atcgaaaccg acttggccaa gatggtagct gatgaactca aggtcaagat
    19621 tcgctatgtg ccggttacag cacaaacccg cggccccctt ctagacaatg aacaggtcga
    19681 tatggatatc gcgaccttta ccatcacgga cgaacgcaaa aaactctaca actttaccag
    19741 tccctactac acagacgctt ctggattttt ggtcaataaa tctgccaaaa tcaaaaagat
    19801 tgaggaccta aacggcaaaa ccatcggagt cgcccaaggt tctatcaccc aacgcctgat
    19861 tactgaactg ggtaaaaaga aaggtctgaa gtttaaattc gtcgaacttg gttcctaccc
    19921 agaattgatt acttccctgc acgctcatcg tatcgatgcc ttttccgttg accactctat
    19981 tctatctggc tacactagta aacggacagc actactagat gatagtttca agccatctga
    20041 ctacagtatt gttaccaaga aatcaaatac agagctcaac gactatcttg ataacttggt
    20101 tactaaatgg agcaaggatg gtagtttgca gaaactttat gaccgttaca agctcaaacc
    20161 atctagtcat accgcagatt aaggaggata ccctatgaca gatttatcat cttggacagc
    20221 ctattttcag gattttggac aatttttcaa tggtttcctc tttactcttg ccctagcgat
    20281 tggatccttt atcctcgcca tggtcttagg aatcttcttt ggtgccatgt caaccagtaa
    20341 acgtccaatt ttacgcattt tagctcgcat cttcgtggaa ttttaccaaa acactcccct
    20401 cttggtgcag tttgttattg ttttttatgg cctacctctt atcagtgacc acatcatcat
    20461 gattccaatt tattggacag ccgttctctg cgtgggactc tatcacggcg cttatatcgc
    20521 tgaggttatt cgttcaggga ttcagtctat tcctagtggt cagatggagg ccgccttgtc
    20581 gcaaggtttt acctatatca gtgccatgcg cttgattatc ttgcctcagg ccttccgcat
    20641 cattctccct ccattgacca accaaattgt taacctcatc aagaacacat ctactgtagc
    20701 tatcatctct ggagtagact tgatgtttgt gactaagtct tggtcggctc tcaacggaaa
    20761 ctatatccca gcctttttag gtgctgctct tctctacttt gccctatgct tccctgttgc
    20821 ccagtttggt cgcaagatgg agcaagccaa taaaaaagcc tattcacttt aggaggttac
    20881 tatggaatct attttagaaa ttttaacccc agataaccta gtctttatct ttaaaggatt
    20941 tggcttgacc ctctatattt ctctgattgc catcatcctc tctactatca tcggtaccgt
    21001 gcttgccgtc atgcgaaatg gaaaaaatcc tatcttacgc attatttcca gtatttatat
    21061 cgagtttgtg cgcaacgttc ccaaccttct ctggattttt actatctttt tggtgttcaa
    21121 aatgaaatcc acaccagcag gtattacagc ctttactctc tttacatcag cagccttggc
    21181 tgagattatt cgaggcggtc tcaatgccgt agacaaggga caatacgaag caggaatgtc
    21241 acaaggcttc acctcagccc aaatcctcta ctacatcatt ctcccacaag ccatccgcaa
    21301 aatgctacca gccatcattt ctcagtttgt taccgtgatt aaggatacca gtctcctcta
    21361 ctctgttatc gccctacaag aactctttgg agccagccaa attctcatgg gccgttattt
    21421 cgaaccagag caggtcttca gtctttacat cctgattgcc ctcatctact tcagctttaa
    21481 cctagcgatt tctagcctgt ctcatatgct agccaaacgt tggcaacaag ctgcagaata
    21541 atactcttcg aaaatctctt caaaccacgt cagcttcacc ttgccgtact caagtacagc
    21601 ctgcggctag cttcctagtt tgctctttga ttttcattga gtataaacag ccactctcca
    21661 gttcaattgg agagtttttt gatgagagta gatatttata gacctcaatt tgacaccata
    21721 cattttctat gataaaatgt aacaaattca tttacaacaa atcgaaatct aaatgaaatg
    21781 gaattttcta tgaaatcagt caaaggacta ctctttatca tagctagttt tatcttgact
    21841 cttttgactt ggatgaacac ttctccccaa ttcatgattc caggactagc tttaacaagc
    21901 ctatctctga cttttatcct agccactcgt ctcccactac tagaaagctg gtttcacggt
    21961 ttggagaagg tctacaccgt ccacaaattc acagcctttc tctccatcat cctactaatc
    22021 tttcataact ttagtatggg cggtttgtgg ggctctcgct tagctgctca gtttggcaat
    22081 cttgccatct atatctttgc cagcatcatc cttgtcgcct atttaggcaa atacatccaa
    22141 tacgaagctt ggcgatggat tcaccgcctg gtttacctag cctatatttt aggactcttt
    22201 cacatctaca tgataatggg caatcgtctc cttacattta atcttctaag ttttcttgtt
    22261 ggtagctatg cccttttagg cttactagct ggtttttata tcatttttct atatcaaaag
    22321 atttccttcc cctatctagg aaaaattacc catctcaaac gcttaaatca cgatactaga
    22381 gaaattcaaa tccatcttag cagacctttc aactatcaat caggacaatt tgcctttcta
    22441 aagattttcc aagaaggctt tgaaagtgct ccgcatccct tttctatctc aggaggtcat
    22501 ggtcaaactc tttactttac tgttaaaaat tcaggcgacc ataccaataa tatctatgat
    22561 aatcttcaag ccggcagcaa agtaacccta gacagagctt acggacacat gatcatagaa
    22621 gaaggacgag aaaatcaggt ttggattgct ggaggtattg ggatcacccc cttcatctct
    22681 tacatccgtg aacatcctat tttagataaa caggttcact tctactataa cttccgtgga
    22741 gatgaaaatg cagtctacct agatttactc cgtaactatg ctcagaaaaa tcctaatttt
    22801 gaactccatc taatcgacag tacgaaagac ggctatctta attttgaaca aaaaaagtgc
    22861 ccgaacatgc aaccgtctat atgtgtggtc ctatttctat gatgaaggca cttgccaaac
    22921 agattaagaa acaaaatcca aaaacagagc ttatttacga aggattcaag ttcaaataag
    22981 taatcatact ctcctgggat ttcccaggag agttttttat agccaaatga aataagacct
    23041 gaacgatgga attttggcat tcaaatcaat tgataagaat attttatagt ggagtgaaat
    23101 aggatacgaa caaattgatt aggaaaatca aatgaattta tagaaatctt ttagcagtta
    23161 tgttgtccta ttctagtttc gaaacgctat agaagcagca ttgtgctagt ctagattcag
    23221 tttactatac taaaacgagt agcttggaat caaaaaaccc accctcacag gcaggtttta
    23281 tctgtattat tcagctagat tatgctttac cttctgaacc gaatacgtcg atacgttctt
    23341 caaccgatgc ttggatagct tttacaccgt cagccaagaa tttacgtggg tcgaagagtt
    23401 ttttcttgtc gtattctgct tcgtttgctt cgtagtcacg agcaaattta cgagttgcgt
    23461 tagcgaatgc gatttggcat tctgtgttaa cgttaacttt ggcaacacca agtttgatag
    23521 ctgcttggat ttgctcatca ggaatacctg atccaccgtg caatacgatt gggaatcctg
    23581 gaagagcttc tgtcaatttt tgcaagtggt caaggtcaag accttcccag tttactgggt
    23641 aagggccgtg gatgttaccg ataccagctg ccaagaagtc gataccagtt tcaaccattg
    23701 ctttagcgtc ttcgattgga gccaattcac ctttaccgat gattccgtct tcttcaccac
    23761 cgatagtacc aacttcagct tctactgaga tacctttagc gtgtgctttt tcaacaactt
    23821 ctttagccaa tttaaggttt tcttcaactg gaaggtgtga accgtcaaac atgattgaag
    23881 tataaccaac ttcgatacac tcaagtgcat cttcgtagtg accgtggtca aggtggatag
    23941 ctactggtac agtgataccc attgattcaa caaggttagc gatcaagttg cgagcaactt
    24001 tgtaaccacc catgtattta gcagcaccca ttgaagtttg gatcaaaact ggagcttttt
    24061 tagcttctgc tgcgcgcaag atagcttgag tccactcaag gttgtttgtg ttaaatccac
    24121 caactgcata accgttgtca cgggctgctt ggacaaattt ttctgctgaa acgattgcca
    24181 ttttatcagg cctcctgtat atttttatgg gtcatcccat ttacattgtt cattttatca
    24241 ctttttgcca aaaaaatcta gtttttcccg cagtttcgat tgattttctt ctaactccat
    24301 ctatgtaaac cctttctctc cctagtcttg gacgactttt ggaaaatcta taaagaaggt
    24361 taaacgattc tcctccatct cgaaacgata agctaatttt tcatgttcta atagactctt
    24421 aaccacaaag agccccatac cagacccctt gaccttgcga ctggcattgt cagaaaaaga
    24481 ctgggctagt ttttcttgtt cctctgagct acagctattt tcgataaaaa gttctccttc
    24541 tctttctcca attcgaacta agccacctgg aacagagtgc ttaatggcat tgctgatgag
    24601 attagaaaga atcaacttca taactgatgg gtttagataa gcctgctgat gggtcaaact
    24661 attgtctatc tggagctctc tttccttggc tagcaaggca taatctttga ccagattttg
    24721 cgtcatctgg aggaggtcaa ttgtttccct atcatctcgc aattcctgca cagaagagag
    24781 ggaaagtatc tgcagaacat ggtgattgag ttcatccaca atccccaagg caactcccag
    24841 atactggtct ctattcttat aacgaccgat attctctctc atattttcga ttaggatttt
    24901 caaactagcc agcggtgttt tcaattcatg agaagctcct cgtaggaatt cgaccttcat
    24961 cttctccagc tggagaatgg cttcattctt ttcatgcaag tccgcaataa cagtcaagag
    25021 atgctggtag aggctattga tttgttcctt gagattgcct atctcatcct tagaatccac
    25081 gcgcaatcgc acttgggaat ccaggtccat catccgacgg gtcacccgct tgatttccaa
    25141 aatcggtgca acaatagtcc gagcgtagat gtaggccacc aagagggaaa tcagaaagga
    25201 ggccagcaag gtatagggaa gaaactggag actgatttgc tccgcttcct tttgtaaatc
    25261 catggaagct agaaactgga gaatcatagt accaccgtct tgcgttttca cctcgcgctc
    25321 ctcaataaag agagaggttg tctggcggtc tgtgtccaga ggaagactgt ccttgacttc
    25381 taacttgtcc tcggtcatct cacctttgac ggtccccttg atatcactag tctgggaata
    25441 caagtctaac acttgctcga tactctgcct atctttccct tctagggact gggcaatggc
    25501 tgttgccttt tgaccaatgg tttcctgacg atgactcaga taagtcgaag gaaaaagaaa
    25561 ataaatagct aaatgaaggc agataaccag aacactaaat atcgagaagg tatagataaa
    25621 tatctttgta aataaacctg ttcgtttcat tttcgctcca atttataacc aacattgcgc
    25681 acagtgagga tacaatccaa gtctagcttt ttccgcaatt ccttgatata aacatcaata
    25741 acacggtcaa agggaacctc atctgtcgct ttccagacgg catcgataat ctgagaccga
    25801 gtcaaggccc ggccttcatt tttcactaga tagtccagaa tttccaactc tttggcattg
    25861 ataggcactt cttgacctgc gaggcttgca ctgtagcttt caaagtccac cttggtatcc
    25921 ttgtaagaaa agattcgtcc tgtatcgtag tagcgcttga aaatcgcgtc caccctcact
    25981 tttaagaggg agagggagaa aggtttttcc agatagccat ctgccaaaga ggcaaaggca
    26041 ctcatcttgt attcctcatc ctgaaaagct gtcaacatca agacaggaac ctgactggtt
    26101 ttacgaatct cagctaggac ttctaagccg ttaagcttgg gcatctggat atccagtaaa
    26161 accagggcca cctcatagct agaaaattgc tccagagctt cctgaccgtc cgctgcctca
    26221 atagtttcat agccacaatc cgtcaaataa tcactgaccc cctcacggat catctcttca
    26281 tcttctacaa ttaaaatttt catactttaa ctgctctcta ttttttattt ttcttagaat
    26341 aaatacctac tctattttct attatagtct cttgctggcc ttttgtctgt aagcaactga
    26401 ccactagata aaacgttgtg aaattccttt ctcataaatt ccataacttt agtatattat
    26461 atttaagcac taaagtacaa agaaagcaac tgaaagcaat gattttcacc actgctttca
    26521 gatttatttt gaattgttaa atagctattc ctatccacta ttcttgaata gaaacacaag
    26581 atgcaatctt tattccagac tcattttttt caaatttatt caccatccag caagagctct
    26641 tttggttgtt ttctaaggag attgcttgaa gcaagcgcca taacgagaac cactagaacc
    26701 aaggcaagga caaaaatgat gataaagtct gatgtctgaa tggaaatgtc taggctcgac
    26761 aaggtcttgc taaagccatc tacttctgca ccgccaccaa ggttagaggc ttgagccgcc
    26821 ttactagcct gtttggcaac acctgaagtc acattggcaa ggacagtgtt tccaattgca
    26881 tgggcagtgt aattagctag gaagtaagca gaaactagag cagggatagc aatcaagata
    26941 gattcggtga tgaattgacc caagatactt gcctgcttga gaccaataga gaggaggatt
    27001 cccacttcct tgcgacgggc attgatccaa agactgagca agagggcaag gagaaggact
    27061 gagaagctca agctacccca gaagaggagg ttggccatct tgtacatacc agagatagat
    27121 tgctcaagag ctgggtagtt agaggagctc ttgacgagtg tgtagctctt ccagttgata
    27181 ccactgatgc cattcaactc tttcataaca tcatccaagt tcttgtctgc tgttacaaag
    27241 aaggttgcgt ccccataaat ggctgtgtct tctgtgtatc cataaagttt tgcagcagtg
    27301 tgaatgtctg taatagctgt gttttcgtaa agttcttgtg agtaggttac tgctgactta
    27361 ttatgaccat caaagagtcc cttgattgtc acttcaactg tttccttggc tcctttttca
    27421 ttatctgcat cgtagatatt agagtccagt ttaaccttgt cccctacttt ccagccgtgt
    27481 ttggctgcca agtccttgtg caagaggatt ttatccttgt cgtcgttggt taagtgctct
    27541 ccttcgacta gtttataaga accagagaca aacttatctt ctttagagga gtcattgaca
    27601 cctgtaatca tcaagctact tccaaaacgt ttggcacgat cagcagtgag attcttcttg
    27661 gtttctggcg tttcaatcag gtcatatcca gtcaaatctc cgatagcgtt gatacgtttg
    27721 acataagact caatggcctt gttttcggtg atttttttga tgtcttcacc cttgatattc
    27781 ccagcaccac gaggcgttcc ttggttgacg cgacgattga tttgcatgga gaagctattg
    27841 gtgatatttt taaaggtctc ctgagaagcc ttggcagtag ctcccttgat tgacaagccg
    27901 accaaactca agctcgccat aaggagaata atcaggaaga tgacaatcga tttgaaaaac
    27961 ttccttgtaa cataggcaaa tgcgttgtgt aacatagatt ccctttctag attttgtttt
    28021 aatcattcta tcaaaataag ctcaaattat ttactagtat tgcgcgtttc agtcagtttc
    28081 ttatccttta attcaagtgt aatatctgac gcttgtgcca cttctttact gtgagttacg
    28141 acaatcacac atttacctgt tttctgggca agtgatttga gtagttcgac aatatctcca
    28201 gcagttttag gatccagatt tcctgttggc tcatcagcta gaataactgg agcttctgag
    28261 accaaactgc gagcaatggc aacacgttgc tgttgaccac ctgataactg gagaacattc
    28321 cgcttaatct ggctttcatc caaaccaagc tcaagaagtg tattcttgct tgcctttttg
    28381 ttgaccaatt ggatattttc cagcggagaa agataatcta tcaagttata attttgaaag
    28441 accagggaaa tatggtgcat gcgatggtaa gaatagccct tcttacgaat atcctctcct
    28501 tgaaaaagga tagaaccttc aacaggacta tctagaccag caagtaggga caagagtgtg
    28561 gattttcctg ctcctgactc cccaataata ctgtaaaatt ttccgggttc aaaattataa
    28621 ttgatctgat ataggactgc ttcagcagta ttcttataac ggtaggtaac atcttgtaat
    28681 tgtaataaag tcatgatttc tccttcttaa ctaatagatg ataaaatttc tttcggtgat
    28741 tttctaaata agaataggaa acaaagggct acagataagc aactaagcag aactagaaaa
    28801 acataggatt ctgcaaaaga taagatgcta gttgataaac tgcttgcttt ggctagtgta
    28861 tcttgtaagc ttacctgatc tccacttgct agtagagttt ggagtaggta agttgtgatt
    28921 ccgtttcctg caacaaatgc tggaagcaaa gctccaagag ataccaaaac tacctctaaa
    28981 cagaattgta ggaagatcga gctcttgcct tttccaagtg caagtaaaat ccccacttca
    29041 tagacccgtt ctctcaacca gagagacaaa accagaatta aggctccagc tcctgctatc
    29101 aacatcccat aaaggaagat ggtcaggaag gtttggaaag ttgcaactga gtctttgatt
    29161 tgttcaaaag ccttgttttc cttttcgact tggtagcctt gattttccaa ggccaagttt
    29221 tctacctgct tcatgagtcc gtccatttcc ttaggatttt ctacatagaa gcgtgctgca
    29281 ctgacttgag cttcactatt gcccaaaagg gtttggctac tttcataatc tgtaaagact
    29341 tgattttcac tgaagtcaga agacaagcct gtgaatttct cttgtttttt accagaaaag
    29401 atgccgataa tctcaaactc tactgtttgt ccttttccag attcagactg accagcatcc
    29461 aagccaatct tgtcatgaag tgaaagaccg ttcttcttag ccaattcttc gtggataagg
    29521 attttcttgg aatccccttt ttgaaggtgt cgcccttctt ttagattgaa agccgaactg
    29581 gtaaaggtta catccttgga tgaatcctca agagccgtta agctaaccaa gttattgtct
    29641 gcagctgata aatcatcacg ctccacgctc tgctcgccag tcactgcttc cttgtctttt
    29701 agttttgcga ccgtctcaag ttcaggagag acattttcca gccccttaat cttgcttaca
    29761 gatgctaggt ctgacaactt gaatgtctga ccattctcta tcttcttaat agaaaaagat
    29821 gtattgagtg atttataaag attgctttct actgttttgt tggacttcat cagagtcaaa
    29881 caggctgaaa ttccggccaa taagaccaat aaaatcagaa ataaaataaa acttctcagt
    29941 cgctttctgc tgacataagc ccaagatctt tggattggat tcatttgtca cctccatatt
    30001 tgtaagacta ttataaaacc caaatatgaa atgtttatga aatacgaaaa aaaatatcga
    30061 gtaggggata atctctagcc cctctcacac caccgt
//
LOCUS       DAVBOM010000026        27949 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBOM010000026 DAVBOM010000000
VERSION     DAVBOM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.026"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ878_001201"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ878_001201"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET3095543.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="VQ878_001202"
     CDS             complement(1995..2927)
                     /locus_tag="VQ878_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET3095544.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSAVCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="VQ878_001203"
     CDS             complement(2924..3781)
                     /locus_tag="VQ878_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3095545.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="VQ878_001204"
     CDS             complement(3785..5131)
                     /locus_tag="VQ878_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3095546.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="VQ878_001205"
     CDS             complement(5144..5428)
                     /locus_tag="VQ878_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3095547.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="VQ878_001206"
     CDS             complement(5432..7462)
                     /locus_tag="VQ878_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET3095548.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="VQ878_001207"
     CDS             7653..8660
                     /locus_tag="VQ878_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3095549.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="VQ878_001208"
     CDS             8663..8863
                     /locus_tag="VQ878_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3095550.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ878_001209"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ878_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET3095551.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ878_001210"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ878_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3095552.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9784..11664)
                     /locus_tag="VQ878_001211"
     CDS             complement(9784..11664)
                     /locus_tag="VQ878_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3095553.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASMIY
                     TT"
     gene            complement(11658..12527)
                     /locus_tag="VQ878_001212"
     CDS             complement(11658..12527)
                     /locus_tag="VQ878_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3095554.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(12611..15256)
                     /locus_tag="VQ878_001213"
     CDS             complement(12611..15256)
                     /locus_tag="VQ878_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET3095555.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(15347..16627)
                     /locus_tag="VQ878_001214"
     CDS             complement(15347..16627)
                     /locus_tag="VQ878_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET3095556.1"
                     /translation="MIYSKEIVREWIDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            16798..18882
                     /locus_tag="VQ878_001215"
     CDS             16798..18882
                     /locus_tag="VQ878_001215"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET3095557.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADH
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(18922..20601)
                     /locus_tag="VQ878_001216"
     CDS             complement(18922..20601)
                     /locus_tag="VQ878_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET3095558.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            21357..22586
                     /gene="arcA"
                     /locus_tag="VQ878_001217"
     CDS             21357..22586
                     /gene="arcA"
                     /locus_tag="VQ878_001217"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET3095559.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            22644..23660
                     /gene="argF"
                     /locus_tag="VQ878_001218"
     CDS             22644..23660
                     /gene="argF"
                     /locus_tag="VQ878_001218"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET3095560.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            23825..24772
                     /gene="arcC"
                     /locus_tag="VQ878_001219"
     CDS             23825..24772
                     /gene="arcC"
                     /locus_tag="VQ878_001219"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET3095561.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            24983..26494
                     /locus_tag="VQ878_001220"
     CDS             24983..26494
                     /locus_tag="VQ878_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET3095562.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            26516..27847
                     /locus_tag="VQ878_001221"
     CDS             26516..27847
                     /locus_tag="VQ878_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET3095563.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEICIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         8235 a         6218 c         5365 g         8131 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatgt tggcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacaaagg catcgacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgataatg tcacgagatg ttagagagaa acgcatacca ggcgttccca
     1501 tagcgatccc gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ctgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc aaatctttct
     2101 tgaacaccca tccgatgaat ttttgttatt ccatcatcag agaataattc acatacagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa
     2341 gcaacgatta caacatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cctttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgaa ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tatcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aacacttcta
     3661 cgatagacaa acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc
     3961 ctcccaaaac tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catggataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagataaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tgtcatcata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatagca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaagtt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaagttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg tgttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcattg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga ggaaattcaa agtcgcgtag aagatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaga acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
     9481 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
     9541 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
     9601 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     9661 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     9721 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     9781 gtattaagtc gtataaatca tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     9841 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     9901 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     9961 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
    10021 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
    10081 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
    10141 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
    10201 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
    10261 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
    10321 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
    10381 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
    10441 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
    10501 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
    10561 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
    10621 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
    10681 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
    10741 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
    10801 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
    10861 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
    10921 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
    10981 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
    11041 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
    11101 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
    11161 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgggcat aggcttcgat
    11221 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
    11281 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
    11341 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
    11401 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
    11461 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
    11521 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
    11581 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
    11641 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
    11701 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
    11761 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
    11821 tgactgatag agccacccag actgatgaca tctggatcga tgagatactg gatattgagc
    11881 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
    11941 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
    12001 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
    12061 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgatgaagt
    12121 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
    12181 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
    12241 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
    12301 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
    12361 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
    12421 aagttttcag gcgttgaaat acttgtctta tacagtattt tcccatcagg agtcagactg
    12481 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
    12541 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
    12601 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
    12661 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
    12721 ctgatatgcg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
    12781 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
    12841 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
    12901 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
    12961 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
    13021 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
    13081 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
    13141 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
    13201 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
    13261 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
    13321 agcggatttg tggattgtca acgaagacag tcaactcagt ttccagagga atgtttgtca
    13381 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
    13441 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
    13501 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
    13561 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
    13621 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatgttgtca tccacactca
    13681 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
    13741 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
    13801 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
    13861 aattagctcc gaggtcttcg attgtagcct ctacaggatg accatccaag tcctccacac
    13921 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
    13981 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
    14041 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
    14101 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
    14161 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
    14221 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
    14281 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
    14341 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
    14401 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
    14461 gaacatattc atcaaaagaa ctatgaacaa agattacatc tgggaagagt tcatttgcca
    14521 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
    14581 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
    14641 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagtta gcaaagagaa
    14701 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
    14761 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
    14821 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
    14881 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
    14941 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
    15001 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
    15061 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
    15121 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
    15181 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
    15241 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
    15301 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
    15361 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
    15421 agagggtcgg atcatctaca tgaaagcttt cgtgcatgac acctgtacca ccatcgcagg
    15481 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
    15541 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
    15601 cgtattctcc ttggtagaaa tatggatttt cagagctcaa aatggtacga cgagtagctt
    15661 gatacacttc atcatcgacc gaacagtagc ccagataggg cgcagctagt agacttggta
    15721 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
    15781 tttcgccctt gctgttggtg gtgtaagcgt agtttttgat tccttcttgg atttcatcct
    15841 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
    15901 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
    15961 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt catacctgtc actgcaaagt
    16021 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtgtct cggacaaaac
    16081 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
    16141 ctgcgacaaa aatctcatca aactgactag tctcgccagt ctctttccag aggagataag
    16201 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
    16261 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
    16321 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
    16381 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
    16441 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
    16501 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg
    16561 gatggtcctt agcccgctct gctacttcat ctatccattc tctaacaatt tctttcgaat
    16621 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
    16681 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttattt ttgaaactcc
    16741 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
    16801 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
    16861 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
    16921 accagtgacc agggtggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
    16981 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
    17041 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
    17101 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
    17161 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
    17221 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
    17281 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
    17341 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt
    17401 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
    17461 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
    17521 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
    17581 tttgaccact gtctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
    17641 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
    17701 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
    17761 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
    17821 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
    17881 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
    17941 gccatgctcg aaacagccag caaagccgac catctcggca tcaatggccg ccacggacta
    18001 gcccaatacc aagaactagg ttacctctct accgaccacc atgaaagtgt tagccatact
    18061 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
    18121 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
    18181 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
    18241 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
    18301 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
    18361 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttatga aattcacgaa
    18421 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
    18481 cacatccctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
    18541 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
    18601 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
    18661 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
    18721 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
    18781 gaatgccgac tgaacaaaac actcgtatca actattcaac accaagacct cttaaaagct
    18841 gaacaactaa ctttcaccct cagctggcta ccaagtcact aataaccaaa agaacctttg
    18901 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    18961 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acagggttgg
    19021 tagatgcaaa tcttttttgc tttcccctgc ttggaattga aggacataaa tctcgtcctg
    19081 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    19141 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    19201 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    19261 aagggaaatc ttggtcaata caggaataga ttgtgcctcg gtaatcatca cgcgcacctt
    19321 ttgtgcctct actagcgaac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    19381 aaattcctgc cagacaccat ccacctctac ttgcacatgg aaagcagaaa tacgttggcc
    19441 taacttcaaa tcttctctca actcaattac atcaaaagtt ttaggagaac ctaagtcgag
    19501 ttctaactgg atgggcaagt ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt
    19561 caaatggcga caagcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    19621 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    19681 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    19741 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    19801 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    19861 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaggatt
    19921 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    19981 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    20041 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    20101 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    20161 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    20221 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    20281 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    20341 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    20401 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    20461 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    20521 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    20581 atgcggtttg attttcttca tcgttatata tctccttctt tagcaacttc tcttgttcac
    20641 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    20701 caactggtag gctcaggatt ttgctcctca atattccctc ttcaaacagc tctgtcatat
    20761 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    20821 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    20881 tctaaactat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    20941 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    21001 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    21061 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtt atttgtgtat
    21121 tttttgaaaa attttttaaa aaaattttat atcctcttta atagaagttt atgaatttgt
    21181 atatatgtat tccatcctat gttatgtata ataacataaa attgtgctaa atatcataat
    21241 ttatattatt ttccgagaaa ttatagccat tgacattacc taggaattgc gttataacat
    21301 acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt ttaaggagga aaatacatgt
    21361 cttcacatcc aattcaggtc ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc
    21421 gtccaggcaa ggagttagaa aacttgttgc cggactatct tgaaaggctt ctttttgatg
    21481 atattccttt cttggaagat gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg
    21541 atgaaggaat tgaggttctc tacctagaac aactcgctgc tgaatcattg acctctccag
    21601 aaatccgcga tcaatttatc gaggaatact tagacgaagc caacatccgt gatcgtcaaa
    21661 ctaaggttgc tattcgtgaa ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa
    21721 aaacaatggc tgggattcaa aaagttgaat tgccagaaat tcctgacgaa gctaaagatc
    21781 taactgactt agttgaatca gagtatccat ttgcaattga cccgatgcca aacctctatt
    21841 tcactcgcga cccatttgca acaattggaa acgccgtatc gcttaaccac atgtttgcag
    21901 acactcgtaa ccgtgaaaca ctctacggta agtatatctt caaataccac ccaatctatg
    21961 gcggaaaagt ggatttggtc tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg
    22021 agctagttct ttctaaagac gtccttgcag taggtatctc tcaacgtaca gacgcagctt
    22081 ctatcgaaaa acttttggtc aacatcttca agaaaaatgt tggcttcaag aaagttttgg
    22141 cctttgaatt tgctaacaac cgtaaattca tgcacttgga tactgtcttc actatggtag
    22201 actatgacaa gttcactatt cacccagaaa tcgaaggcga ccttcacgtt tactcagtta
    22261 cttacgaaaa cgaaaaactt aaaattgttg aagagaaagg tgacttagct gaacttcttg
    22321 ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg cggtggtggc aatatcgtag
    22381 cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt gaccatcgca cctggtgtgg
    22441 tagttgttta tgaccgcaat accgtgacca ataagatttt ggaagaatac gggcttcgct
    22501 tgattaagat tcgcggaagt gaattggttc ggggccgtgg tggacctcgt tgtatgtcta
    22561 tgccatttga acgtgaagaa gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa
    22621 aaatagaaag aggaaataat aaaatgacaa attcagtatt ccaaggacgc agcttcttag
    22681 cagaaaaaga ctttacccgt gcagagttag aataccttat tggtctttca gctcacttga
    22741 aagatttgaa aaaacgcaat attcaacacc actaccttgc tggcaagaat atcgctctcc
    22801 tatttgaaaa aacatctact cgtactcgtg cagcctttac aactgcggct atcgaccttg
    22861 gtgctcaccc agaatacctc ggagcaaatg atattcagtt gggtaaaaaa gaatctactg
    22921 aagatactgc taaagtattg ggacgtatgt ttgacgggat tgaattccgc ggattcagcc
    22981 aacgtatggt tgaagaattg gcagaattct caggcgttcc agtatggaac ggtctaactg
    23041 acgaatggca cccaactcaa atgctcgctg actacttgac tgttcaagaa aacttcggtc
    23101 gcttggaagg cttgacattg gtatactgtg gtgatggacg taacaacgtt gccaacagct
    23161 tgctcgtaac aggtgctatc cttggtgtca atgttcacat cttctcacca aaagaactct
    23221 tcccagaaaa agaaatcgtt gaattggcag aaggatttgc taaagaaagt ggcgcacatg
    23281 ttctcatcac tgaagatgct gatgaagcag ttaaagatgc agacgttctt tacacagacg
    23341 tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg tgtagctctt cttaaacctt
    23401 accaagtcaa tatggactta gttaaaaaag caggcaatga aaacttgatc ttcctacact
    23461 gcttgccagc attccacgat actcacactg tttatggtaa agacgttgct gaaaaatttg
    23521 gtgtagaaga aatggaagta acagacgaag tcttccgcag caagtacgct cgccacttcg
    23581 atcaagcaga aaaccgtatg cacactatca aagctgttat ggctgctaca cttggtaacc
    23641 tttatattcc taaagtataa ttttagataa taaaccgtct accaacagct atgagggctg
    23701 cgactaatag ctttagtccg gtcctctttt atataatggt aatctattat ttcttataaa
    23761 atatgtgaaa aatcattaaa ttgaaatcta aacgcattct attgagtgtg ataaaggaga
    23821 atttatggca aatcgtaaaa ttgtagtagc tttgggagga aatgcgattc tttcttctga
    23881 cccatcagca aaggctcaac aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt
    23941 gattaaaaat ggagatgatt tgattatcac tcacggtaat ggacctcaag ttgggaatct
    24001 cttgctccaa catttggcat cagactctga aaagaaccct gccttcccac tcgactcact
    24061 tgtcgctatg acagaaggta gcatcggttt ctggttgaaa aatgctttgc aaaatgctct
    24121 cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta acgcaagttg tcgtagataa
    24181 aaatgatcca gcttttgtta acttgagtaa accaatcggt cctttctatt cagaagaaga
    24241 agcaaaagca gaagccgaaa agagcggagc gactttcaag gaagatgctg gccgtggctg
    24301 gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac
    24361 tcttttaaat agtggtcaag tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa
    24421 agaaaacaat ggacatttga ctggtgtcga agcggttatt gataaagact tcgcttccca
    24481 acgtttggca gaattggttg atgcagacct cttcatcgtt ttgacaggtg tagattatgt
    24541 atttgttaac tacaacaagc caaaccagga aaaattggaa catgtgaatg ttgcccagct
    24601 ggaagaatat atcaaacaag atcagtttgc accaggtagc atgcttccaa aagtagaagc
    24661 agctatcgct tttgtcaatg gtcgtccaga aggaaaagca gttattactt cccttgaaaa
    24721 tctaggcgcc ttgattgaat ctgaaagtgg aacaattatt gaaaaaggat aagttgtttt
    24781 actaataaga tgtattctat ttctagtatc tttatatcaa attagaaatt attcttgaaa
    24841 acatgtacaa tatttcaaaa gatattagtt ttttagactt taatatggta aaacaaatat
    24901 aaatagaaag cgttttctta aatgtttatt taagaaagta gttggttttt tacactttgt
    24961 tagacatcag gaggaaaaac aaatgagtga aaaagctaaa aaagggttta agatgccttc
    25021 atcttacacc gtattattga taatcattgc tattatggca gtactaactt ggtttatccc
    25081 tgcgggggcc tttatagaag gtatttacga gactcagcct caaaatccac aagggatttg
    25141 ggatgtcctc atggcaccga ttcgggctat gctaggtact catccagagg aaggttcgct
    25201 cattaaagaa acgagcgcag cgattgatgt agccttcttc atccttatgg ttggtggttt
    25261 ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa
    25321 gtataagggc cgcgaaaaaa tgttaatttt ggtactaatg cctttgtttg ccctcggtgg
    25381 tacaacttat ggtatgggtg aagaaacaat ggccttctat ccactccttg tgccagttat
    25441 gatggccgtt ggttttgata gcctgactgg tgttgcaatt attttgctcg gttctcaaat
    25501 cggctgtttg gcatctactc tgaatccatt tgcgacaggt attgcttcag cgactgcggg
    25561 agttggtaca ggggacggta tcgtacttcg tctgatcttc tgggttacct tgactgctct
    25621 tagtacttgg tttgtttacc gttatgcgga taagattcaa aaagatccga ctaagtcact
    25681 ggtttatagt actcgcaaag aagatttgaa acactttaac gtagaagaat cttcatctgt
    25741 agaatctaca cttagcagca aacaaaaatc agttctcttc ttatttgtgt tgacattcat
    25801 cttgatggta ttgagcttca ttccatggac agaccttggc gttaccattt ttgatgactt
    25861 taatgcttgg ttgactggtc ttccagttat tggtaatatt gtcggttcat ctacttctgc
    25921 actaggtact tggtacttcc cagaaggcgc catgctcttt gcctttatgg gtatcctgat
    25981 tggtgttatt tatggtctta aagaagataa gattatctct tccttcatga atggtgctgc
    26041 tgacttgctc agtgttgcct tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa
    26101 cgacggtatg attaccgata caatcctcaa ctggggtaaa gaaggcttga gcggtctatc
    26161 ttcacaagtc tttatcgttg taacttatat cttctatcta cctatgtcat tcttgatccc
    26221 atcttcatct ggtcttgcca gcgcaactat gggtatcatg gctccacttg gagaatttgt
    26281 aaatgtccgt cctagcttga ttatcactgc ttaccaatct gcttcaggtg tcttgaactt
    26341 gattgcacca acatctggta ttgtgatggg agctcttgca cttggacgta tcaacattgg
    26401 tacttggtgg aaattcatgg gcaaactcgt agtcgctatt attgtagtga ccatcgccct
    26461 tcttctcctt ggaaccttcc ttccattcct ataaaatagt gagtgaggtg attccatgaa
    26521 aatagatata acaaatcaag ttaaagatga atttcttata tcattaaaaa ccttgatttc
    26581 ctatccttca gtactcaatg aaggagaaaa tggaacacct tttggacaag caatccaaga
    26641 tgtcctagaa aaaactttag agatttgtcg agacataggt ttcactacct atcttgaccc
    26701 taaaggttat tacggatatg cagaaatcgg tcagggagca gagcttctgg ccattctctg
    26761 tcatttggat gttgttccat caggtgatga agcagattgg cagacaccgc catttgaagc
    26821 aactatcaaa gacggctggg tattcggacg tggtgtccaa gatgataaag gcccttcgct
    26881 cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt attcagttca aaaagcgcgt
    26941 acgctttatc tttggtaccg atgaggaaac cctctggcgc tgcatggcac gctacaatac
    27001 catcgaagaa caggccaaca tgggctttgc acctgactca tcttttcctc tgacctatgc
    27061 tgaaaaaggg cttctacagg tcaaacttca tggccctgga tcggatcaac tagagcttga
    27121 agtaggaggc gcctttaacg ttgtaccaga caaggccaac taccaaggtc ccctctatga
    27181 acaggtttgt aacggtctca aagaaactgg ttatgattac caatccactg aacaaaccgt
    27241 aacggttctc ggagtgccaa agcatgctaa ggatgctagt caaggtatca atgctgtcat
    27301 ccgactagct accattcttg ctcctctcca agaacaccct gctctcagtt ttcttgcaac
    27361 acaagcaggt caagacggca caggaagaca aatctttggt gatatagcag atgaaccttc
    27421 tggtcaccta tcctttaatg tcgcaggtct catgatcaat catgaacgtt ctgaaatctg
    27481 tattgacatt cggactcctg tcttagctga taaggaagaa ctagtagagt tgcttacaag
    27541 atgtgcacaa aactaccaac tccgctacga agagtttgac tatctagcgc ctctatacgt
    27601 cgcaaaagac agtaaactcg ttagcacact gatgcaaatc taccaagaaa agactggcga
    27661 taacagtcct gctatttcat ccggtggtgc cacttttgct cgcaccatgc caaattgtgt
    27721 agccttcggc gccttattcc caggagcgaa gcagacagaa catcaggcaa atgaatgtgc
    27781 cgttctagaa gatttgtacc gtgctatgga tatttatgcc gaagccgtct atcgacttgc
    27841 aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc gattaatgaa ctgcacccca
    27901 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaatt
//
LOCUS       DAVBOM010000027        26014 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBOM010000027 DAVBOM010000000
VERSION     DAVBOM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.027"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(15..311)
                     /locus_tag="VQ878_001222"
     CDS             complement(15..311)
                     /locus_tag="VQ878_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095564.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ878_001223"
     CDS             complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ878_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET3095565.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3584..4810)
                     /locus_tag="VQ878_001224"
     CDS             complement(3584..4810)
                     /locus_tag="VQ878_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET3095566.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4853..5545)
                     /locus_tag="VQ878_001225"
     CDS             complement(4853..5545)
                     /locus_tag="VQ878_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET3095567.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(5731..7482)
                     /locus_tag="VQ878_001226"
     CDS             complement(5731..7482)
                     /locus_tag="VQ878_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095568.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7472..9217)
                     /locus_tag="VQ878_001227"
     CDS             complement(7472..9217)
                     /locus_tag="VQ878_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3095569.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9423..9719)
                     /locus_tag="VQ878_001228"
     CDS             complement(9423..9719)
                     /locus_tag="VQ878_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET3095570.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9872..10328)
                     /locus_tag="VQ878_001229"
                     /pseudo
     CDS             complement(9872..10328)
                     /locus_tag="VQ878_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10461..11288
                     /gene="xth"
                     /locus_tag="VQ878_001230"
     CDS             10461..11288
                     /gene="xth"
                     /locus_tag="VQ878_001230"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET3095571.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAKNADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11300..11443
                     /locus_tag="VQ878_001231"
     CDS             11300..11443
                     /locus_tag="VQ878_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3095572.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11443..11682
                     /locus_tag="VQ878_001232"
     CDS             11443..11682
                     /locus_tag="VQ878_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3095573.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDPYIYPHEFAVLDPDGYFLRFSE"
     regulatory      12065..12160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12560..13141
                     /locus_tag="VQ878_001233"
     CDS             12560..13141
                     /locus_tag="VQ878_001233"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET3095574.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13141..14403
                     /locus_tag="VQ878_001234"
     CDS             13141..14403
                     /locus_tag="VQ878_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET3095575.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14490..15356)
                     /locus_tag="VQ878_001235"
     CDS             complement(14490..15356)
                     /locus_tag="VQ878_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET3095576.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15343..16113)
                     /locus_tag="VQ878_001236"
     CDS             complement(15343..16113)
                     /locus_tag="VQ878_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3095577.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16139..16993)
                     /locus_tag="VQ878_001237"
     CDS             complement(16139..16993)
                     /locus_tag="VQ878_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET3095578.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17150..17554)
                     /locus_tag="VQ878_001238"
     CDS             complement(17150..17554)
                     /locus_tag="VQ878_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET3095579.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17624..19105)
                     /locus_tag="VQ878_001239"
     CDS             complement(17624..19105)
                     /locus_tag="VQ878_001239"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET3095580.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19124..20302)
                     /locus_tag="VQ878_001240"
     CDS             complement(19124..20302)
                     /locus_tag="VQ878_001240"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET3095581.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAFDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEVFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20466..21473
                     /gene="galR"
                     /locus_tag="VQ878_001241"
     CDS             20466..21473
                     /gene="galR"
                     /locus_tag="VQ878_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET3095582.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21519..22556)
                     /locus_tag="VQ878_001242"
     CDS             complement(21519..22556)
                     /locus_tag="VQ878_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3095583.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22557..22910)
                     /locus_tag="VQ878_001243"
     CDS             complement(22557..22910)
                     /locus_tag="VQ878_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3095584.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23154..24044)
                     /locus_tag="VQ878_001244"
     CDS             complement(23154..24044)
                     /locus_tag="VQ878_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET3095585.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24177..24713
                     /locus_tag="VQ878_001245"
     CDS             24177..24713
                     /locus_tag="VQ878_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3095586.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24879..25685)
                     /locus_tag="VQ878_001246"
     CDS             complement(24879..25685)
                     /locus_tag="VQ878_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET3095587.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
BASE COUNT         7804 a         5738 c         4613 g         7859 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
      721 aggttctttc ccatttgcat tagatttgat gactgatata tacttaccgg ataaattata
      781 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
      841 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
      901 atttggttgt tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc
      961 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1021 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1081 tttagtgttt ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac
     1141 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1201 tgtaaaacgt acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1261 agaggggttc tgtgtcgaca atgtttgata gtgtgtacca attgctgtta ctaattcccc
     1321 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     1381 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     1441 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     1501 attatcaact aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc
     1561 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     1621 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     1681 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     1741 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     1801 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     1861 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     1921 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     1981 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2041 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2101 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2161 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2221 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     2281 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     2341 tgaaattgcc aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc
     2401 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     2461 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     2521 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     2581 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     2641 atagtaaatt gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     2701 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     2761 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     2821 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     2881 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     2941 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3001 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3061 aaaatactgg aatagggcat ataggtaata gtagacaagt gttttataga ttgtctcgcg
     3121 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt gttattataa
     3181 tatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3241 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     3301 ggaaactcac gtctttcaaa aaatagggtg aattaaaaac tagaacaaga cactagattt
     3361 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     3421 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagagag
     3481 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     3541 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     3601 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     3661 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     3721 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     3781 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     3841 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     3901 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatat
     3961 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4021 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4081 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4141 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4201 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4261 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     4321 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
     4381 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     4441 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     4501 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
     4561 aggttatggc tggaacgatg acttcatcac caggtcccac ttcaaaaacg cgtaaaatca
     4621 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     4681 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     4741 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     4801 aatttggcat tgatttgctc cttttatctg tactcattct cttatgacta ctttatttta
     4861 gtaccttaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     4921 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     4981 ctgacagacc tttctctgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5041 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gtgctatact
     5101 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5161 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5221 taatacggct atcgttagca gaagtcacca gatttccttt tttatccgca tccgtcacca
     5281 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     5341 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     5401 aggtcagaac cagtaagacc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
     5461 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
     5521 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
     5581 acactttttg tcaacacttt tcattatacc acaaaatgga aaaggcggtg aaaaaaatct
     5641 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     5701 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     5761 caaactatac atcttgtgat aggttcctcc cagagccaag agttcctcat gggttccact
     5821 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     5881 gcggtgagct atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     5941 caagctttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     6001 ctggctggcg actgttctag caaaggcaag aagctggcgt tgcccagtag agaagctcga
     6061 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     6121 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     6181 attggactta atagttccat gatagaggaa gggttcctgc aagaccaaac cgatgttttt
     6241 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     6301 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     6361 acctacaaag gcaatggttt cacccttatt aacagagaaa gaaatgtcat ccagaatcgg
     6421 atgtttaccg tcatatgaga aacacacatg ttcaaagcgg atattgcctt cttggacttt
     6481 ggcttgccca ttttcttgaa gaggttcata ggtcctctcg tctaccaggg caaagacacg
     6541 acctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     6601 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     6661 agaaagacca cgatagccaa aataggccat caagacagca taacctagaa gtttcaacaa
     6721 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg catagaccaa
     6781 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     6841 gattattctg attccctcga tgttttcagc cagcttgcta ttgatatctg acaagagact
     6901 tctggttttc tcaatgattt tcactgattt tttccgatag agattgacca aaaggaaaat
     6961 caaggggaga aagagcaaga ctaatgctgt caaacgaaaa tccaatacca acatggtata
     7021 aagggttgtc agaaagatga aaactgctga gataaagcta gataaaatcc cagaaaacat
     7081 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     7141 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatcccgac gaatatccct
     7201 aacaatactg taagacacgc gcgcaaagag aagattgccg acatactgaa ctacagtttg
     7261 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     7321 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     7381 cgctaggaga aaactgagtg ccaaaaaggt caggagtcta taaggcttga gataagacat
     7441 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     7501 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     7561 gcctgcctcg ttcgataatt tgaccatttt gtagaactaa aataaaatct gcatggacaa
     7621 cagcactgag gcgatgggca gttataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     7681 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     7741 agatatcagg gtttaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     7801 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     7861 cttggtaaac tcgggctagc ttagtagctt cctcaacctc tgaaaggggc aagttaggat
     7921 tgccaaagcg gatattgtct aggattgaag tcgcaaagag aaactggtcc tgaggaacat
     7981 agcccatgag actgcgaagt tctgtcaaac gatagtcccg aatatcgtga ccgtttagat
     8041 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     8101 cagagcctgt ctgcccaacc aagcccagtg tttgcccttt tgccaaacta aagtgaatat
     8161 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggcatactcc aaacgcccat
     8221 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     8281 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     8341 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttaccaactg
     8401 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     8461 caacaaacaa gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     8521 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     8581 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     8641 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     8701 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     8761 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     8821 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     8881 tccgataggt ttgataaaag gctggcgaca tttttgtgaa atgcttaaac aagcgagacc
     8941 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     9001 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     9061 gggttaattg ccccgatgtg atggcatcaa tgactcgccc cataaccata ggaggaatga
     9121 gattgagaac ggaaaccaag accagggcca caatcccgac tagataacgg tgtttttcta
     9181 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     9241 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     9301 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     9361 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     9421 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     9481 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     9541 atcgattcca agacgtctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     9601 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     9661 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     9721 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     9781 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagatc
     9841 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     9901 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     9961 gggcacgata atagcgatct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
    10021 taacatggac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
    10081 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
    10141 aaagcatagc taaataaggc cagagctgaa atcatgacca actcacgaaa tttggttcct
    10201 tttttatcat ggtatgcctt gaaagcaaaa aaaactgtca cagctaatag aacaatccca
    10261 aagccaacca tgataccatt ttgctgaccg atttggctga gtacatagtc ataagagtag
    10321 aatttcatgt attttcactc cctttcataa aatcattctt aattataaac gaaagagagt
    10381 aatttttcaa accatacgtt ggggaaatag ctcttttttt ggtataataa aatctataat
    10441 ctgaatgaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
    10501 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
    10561 ctaaaaatgc tgatattatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
    10621 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgttctt
    10681 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt tctttataag aaagaactta
    10741 cacctactat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggtcgta
    10801 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
    10861 acggtctcaa acgcttggaa gaacgccaag tctgggatgc caaatatgct gagtatttgg
    10921 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
    10981 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    11041 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    11101 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    11161 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    11221 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    11281 atttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    11341 tatcgaacag tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    11401 tccagaagaa aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca
    11461 aaggatcaac tagctgaact gacctatcca tttggtcgtg gagtcaatct ctcctttggc
    11521 ataaaggatg tttcaaaact ctatcaaaga gtgatgaagg caaactatcc tatttatcgt
    11581 cccttgacca aaagaaagtt tcgtgtcagt gatccctata tctatcctca tgaatttgca
    11641 gttttggatc cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa
    11701 aagtctttaa agttagaaaa aggcatattg tcaggtgttt aaaaacttga tagtatgcct
    11761 tttatgatgg aaaaatcttc taatactctt cgaaaatctc ttcaagccac atcaacgtca
    11821 ccttaccata ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt
    11881 tttgaggttg tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag
    11941 cttacaacgg agtttttgtt caccccctct tctgtttgtt cgttttttaa atcaaaacac
    12001 taacaaaata gttgatttat aaagttattt agtgtaaaat aaaaacattg gctcaagcct
    12061 atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa
    12121 ggtgccggaa cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgc
    12181 ctatttgggg gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc
    12241 cttaattagt gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa
    12301 tttcatccct aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt
    12361 ccccgaacta ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    12421 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    12481 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    12541 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    12601 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    12661 gatgcgagag attggtaggg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    12721 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    12781 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    12841 tcaagtctac tcctttacca aacaggtgac cagcaccgtt tctatcgctg gaaaattcct
    12901 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    12961 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    13021 tgagaaatcc ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    13081 acttgctcgt ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    13141 atgcaaactc aagaaaaaca ctcgcaagca gccgttcttg gcttgcagca cttactagcc
    13201 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    13261 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    13321 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    13381 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    13441 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc
    13501 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    13561 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    13621 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    13681 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    13741 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac
    13801 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    13861 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    13921 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    13981 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    14041 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    14101 cttcctaagt ttggtgccct tgcccaaatc attccaagct ccgtcctcgg cggtgccatg
    14161 ctggtgatgt ttggttttgt atctattcaa gggatgcaaa tcctcgcccg agttgacttt
    14221 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    14281 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    14341 atcgtcgtag ccagcctact cgccattgtc ctcaatgccg tattaaatca taaaaagaaa
    14401 taagaaaaag aggtgcgagc ctcttttttg tttatcacaa attgattata aatacaatca
    14461 atcccaattc ccatctaatt gaattggacc tatttcaaat tctttaaaat attatgttcc
    14521 aaatcgttaa tattatataa gaatggtaaa atatcaaatg tttctcgtaa attattctta
    14581 gccttatacc aaccttgtcc atcagtaatc cacataaact caacattagg aatagcttta
    14641 atttcttcag caatcatttt gtaagatcta gccgtctcat ttaattttga accacttcct
    14701 gaataaaaat taacctcaat cagataaagc acttgttcat tttttatgac aaaatcaaaa
    14761 cgtttcacag tattcccatc attcgtaata gcagataaat cgacagaaaa aatttcctct
    14821 atttcatttt gttcaatctc tttaaataaa ttctctccta aaatataccc ttcagcttca
    14881 agatagcttt gaacaatatt ttccatcgca tctccagtcc gatttttgcg cccattagta
    14941 tccataccaa cctcaacacc tgtaacgtag tcaactaaat ttgatactaa atgattttgc
    15001 aataaatcaa atatacctga tttttccaaa aacatagtat attcttcaat actatagttt
    15061 cgtttactaa aatcaaaata gaaatctttt atcggatcct taacaataat cgtatctctc
    15121 aaacgtttag caataagtag aggcacaact ttcaaaattt ctggataatt ttgatataag
    15181 tctaaaaaat cctcttgtat atttttacta ccaataagac tattcataat atttagagca
    15241 acttttatac tagatacatt tttataaacc ttaggaaaat ctgtataata agtccagtca
    15301 gctactgtgt cggtcatcgt tgacaaccac tcatcaaaat ttctagtttg tttcattttc
    15361 tgcctccaac ctcttccttg caatttttaa atattctttt tcagcatcga tacctataaa
    15421 tcttctacct aaccgcttcg caacaacacc cgtagtgcca ctaccaacaa atgggtctag
    15481 aatatagtca ccctctttag tagaggctaa aataatgcgt tctaacaaat actctggttt
    15541 ttgagttgga tgtttcccag cccatttttc aactttcttt gttaaagaac cggtccagac
    15601 atctttcatt tgttttccat cattcaattc tttcattaaa tcataattgt agtaatgacg
    15661 agctttttta tcattttttc tggcccataa aatggtttca gtagaatggg taaaataacg
    15721 acaagataaa ttgggggcag ggtttgtttt ctgccaagta atattattca gaattttaaa
    15781 accttcttgt tctaatgcca ttccaactga gtatatgttg tgcaaactac ctgaaatcca
    15841 taccgtccca ttaggcttca gaacttcttt tgctaggcga atccatttac gattaaactc
    15901 atgtttttct tcgaatgaag aaattttatc ccaatctcct ttatcaacag aaacaacttg
    15961 tcccccagaa ttagatattc caccattact taaaaaataa ggtggatcag caaaaatcat
    16021 atccatactt tctggtttca tttttgataa gaacttgaac gtatctgaat gaacaagaat
    16081 catcttattt ttattgtagt atggttttgt cataagaaca cctccatact tatattcgtt
    16141 atttttcata atttgtgact ataatttcag aaatttttcc tcgacttgaa gattttgctc
    16201 cattagttcg ggtagcttca acataatgta tattaaaatc cttatacaac tcctctacta
    16261 aagcactaga agaatttgat aacataacat aagctcctgt atcactcaat ctcttaaagg
    16321 catctcttaa tcttacttga tctgcaaaag agaatccctc atgagtataa gacgtaaatg
    16381 cactcgtctc agacaatgga atatatggag ggtcaaaata cacaaaatct cctgttcgaa
    16441 catctacaat tgccttttca aaatctccca ctttaatttc tagttgattg ttatttatat
    16501 aaactgaaat agcagatatc aattcctcat caacaatttt aggattctta taacgtccat
    16561 atggaacatt aaattgattc ttagaattca cacgatatag accattaaag ttcactctca
    16621 acatatatag aatacgtgca gctctttgta cttcggacat catatctatt ctttcatcac
    16681 gatctgcaga acgtaaatct aaataatatt cttttgaatt atattcctga tgaactttca
    16741 aaatttcaat caattcttga ggattgtcct taatttgttg atagcaattt attagttcag
    16801 cgttaaaatc attaataact gcatctttag gagccaaatc aaaaaataaa gctccacctc
    16861 caacaaaagg ttcgaaatac ctgttatagg ttttaggcat taattctcta ataacaggca
    16921 ataattgtct tttaccacct gtccatttcg tgaacggttg taaagtaact ttctttattt
    16981 cttttatctt catgctttta attataccat agaaattaaa acacaactct tgtattttct
    17041 accacattac taaattttct attttagaat taaatcatat caatatcaaa aaatgagtaa
    17101 ggcaaatctt ataaattcca aaattcacct cactctatta aattactctt tatatcctta
    17161 cctgtctttc ttctgaccgc tggcctgtga caaacatggt aaaggttgct ttacagacat
    17221 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    17281 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    17341 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    17401 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gacgagttca
    17461 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    17521 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    17581 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    17641 cgacctgttc cacaaagcgc ataaaggctg tctgaccttg ttctgtctgc ttgtagactc
    17701 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    17761 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    17821 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tccacttctt
    17881 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    17941 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    18001 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    18061 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    18121 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    18181 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    18241 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    18301 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    18361 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    18421 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    18481 catagggcga atactggaac ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    18541 ggttgctgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    18601 gacactgagg ataattacta gcttgcacca acttggctac cgcaatctct ttcggatcct
    18661 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    18721 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttccga ctgagttgat
    18781 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    18841 cctgactcgg acaaggagtc accaagtcca tcagttcagt accaaggatt tcacgcgcag
    18901 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    18961 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    19021 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    19081 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    19141 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    19201 gtttgcctac agcttcctta aagacctcaa cagtatcttt ttgaaccaag gcaatggcac
    19261 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    19321 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    19381 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    19441 ctttaagggt gcgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    19501 ctttaatcag atagctatat tggtcaaagg cccactcgtc caattcaccc aaggtctgaa
    19561 tatccaaggc aacttgcaac tcttccactg ctttttcaca ctcagcacga cgttcattgt
    19621 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    19681 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    19741 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    19801 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    19861 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    19921 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    19981 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    20041 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    20101 gcaaaacttg gtcgtcacgc ttacgagctg caccgtaagt tcccaaggaa atagcagcag
    20161 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    20221 aaaagaaagt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    20281 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    20341 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    20401 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    20461 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    20521 cccgtgtcct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    20581 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    20641 ccaagcaaaa gattgccatt atccaatggg tcagcgaaca aggggagctg gacgacctct
    20701 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tatgatatct
    20761 tgcgctattt taatgaccat ccttttacct taagcgagga agtgattggg attctctgca
    20821 ttggaaaatt tagccgagct cagatttctg cctttgaaga ataccaaaaa cccctggtct
    20881 ttctagacag tgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    20941 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    21001 caggccttga agaaacgact gaccaagaag aaatcattca ggataagcgg ctggaaaatt
    21061 tcagaaacta cagtcaagca aaaggaatct atcatgatga actggtcttt caaggaaact
    21121 ttactgccca gtctggctat gacttgatga aggaagccat tcagagcttg ggagaccaac
    21181 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    21241 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    21301 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    21361 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcgcaaaatt cctagcctga
    21421 ccatgctggg aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca
    21481 taaaaaacga atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac
    21541 ttaattgtct tacgttcatc catatcttta taggcttggt cgatatcttc cagtttataa
    21601 cttgaagtaa agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat
    21661 tgcttatcgt atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat
    21721 gtcgaaccaa gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca
    21781 ttatgaagaa cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct
    21841 gcatctgctc ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct
    21901 gcaacaacag ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc
    21961 ataaggataa tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca
    22021 gccccatcac cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca
    22081 tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg acttgagcat cccttctgta
    22141 tagtcagaag gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata
    22201 tattctgcct gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca
    22261 aatccagcaa gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa
    22321 tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt caacaatccc aatcgcttcg
    22381 tgtccactat ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa
    22441 ccacaaacgc acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga
    22501 cgttcaatgc tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa
    22561 aattttcctt ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc
    22621 tgagacaagc gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct
    22681 ctcgtttcat ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca
    22741 cccgccgaac gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca
    22801 cgaatcccag tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga
    22861 atcgtatccg ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct
    22921 cctctcattt cattcactga attcacgcta ttctaactca cttatcttat tatataactt
    22981 tgagttgact ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc
    23041 atatatctgg agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata
    23101 aagaaattac tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt
    23161 tgatgctcat aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct
    23221 aggtcagcat caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga
    23281 atagactctt tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca
    23341 tttttttcca aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc
    23401 aatcgttcca ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag
    23461 aaaatcttga gtgtagacca aaaacgtgaa agggcttttg aaagaataaa gaaagaaatg
    23521 acaagggaca aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc
    23581 aggataacag ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca
    23641 ttctttgtct ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata
    23701 attcctaacc agagaatccc ctcatcattg actggttgcg gatgcaaaat cttcgtgaca
    23761 ttttccaaaa tgactagaac agagcctgtt acgagaatca cagctgttac caaggctcct
    23821 agcaggctaa accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt
    23881 gtttctagaa aagctgatat tccaattgca atcacatctc ccaagtcatg cacagagtca
    23941 gcaagaacag cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc
    24001 aaatttaaga aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg
    24061 ttataatagg tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg
    24121 atagaagcaa aacgtcagct ttattcagtt ctgaacaatt tgccttaagt gtccatatga
    24181 ctaacattga ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac
    24241 ttttgaatgc taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg
    24301 tgggaagatc caccttttac tgtcactatg aaagtaagga gcttcttctg gaccagctct
    24361 gccgctacct cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc
    24421 tcgcccacct ctttctccat tttcataaaa accaagacca tatcaccagt ctgctatttt
    24481 ccaaaaatga ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg
    24541 tgctagctga taatttaaaa gaagcccacc ctaatatgcc tacttcttac ctccaacact
    24601 tggtcgtgtc caactttatc gagacattga cctggtggct caaaaaaggt caagatttca
    24661 cagaccagga agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga
    24721 gtaaagctca gttgtcttat ttctaggtta ctgagttttt tatcttttca acaacaaaag
    24781 aggacccgcc gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt
    24841 aatcgaaatc tcaaaacagc actttcaaac atcttttcct agttaggtaa atcagtattc
    24901 tgcttagctg ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaga
    24961 tatttccctt gaatttgcag gctttctccc caccagagat agattgaaaa aacattggta
    25021 gccgcccaga atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca
    25081 ttggttgcat ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg
    25141 aagccaaagg ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg
    25201 tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa
    25261 actagaagtc caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa
    25321 aagcctttct gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa
    25381 ttacttgctc gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc
    25441 atcccaatcc agtcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt
    25501 cctaaaacca gcaaataaat ccactgggca aaactacgat gggcaaagag gtcatcccag
    25561 atagccttca tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa
    25621 ccacctgaca tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta
    25681 tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg
    25741 ctctattaga taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga
    25801 aacctcttat ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac
    25861 tgtctttaca gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt
    25921 gacattcagt cattctcaca tcaaaaaagc ccagacgaaa ctgtctgagc attcttttat
    25981 ctagtcgttt aaggaagttg agttcagtat gttt
//
LOCUS       DAVBOM010000028        25826 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBOM010000028 DAVBOM010000000
VERSION     DAVBOM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.028"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            59..772
                     /locus_tag="VQ878_001247"
     CDS             59..772
                     /locus_tag="VQ878_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET3095588.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            786..1433
                     /locus_tag="VQ878_001248"
     CDS             786..1433
                     /locus_tag="VQ878_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095589.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            1571..2224
                     /locus_tag="VQ878_001249"
     CDS             1571..2224
                     /locus_tag="VQ878_001249"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET3095590.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTSWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            2234..2698
                     /locus_tag="VQ878_001250"
     CDS             2234..2698
                     /locus_tag="VQ878_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3095591.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            2711..3979
                     /locus_tag="VQ878_001251"
     CDS             2711..3979
                     /locus_tag="VQ878_001251"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET3095592.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            3993..4253
                     /locus_tag="VQ878_001252"
     CDS             3993..4253
                     /locus_tag="VQ878_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095593.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ878_001253"
     CDS             4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ878_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET3095594.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            5779..6747
                     /locus_tag="VQ878_001254"
     CDS             5779..6747
                     /locus_tag="VQ878_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET3095595.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            6763..7755
                     /locus_tag="VQ878_001255"
     CDS             6763..7755
                     /locus_tag="VQ878_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET3095596.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            7973..9016
                     /locus_tag="VQ878_001256"
     CDS             7973..9016
                     /locus_tag="VQ878_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET3095597.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            9076..10761
                     /gene="lpdA"
                     /locus_tag="VQ878_001257"
     CDS             9076..10761
                     /gene="lpdA"
                     /locus_tag="VQ878_001257"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET3095598.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAIAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIVDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            10825..11814
                     /locus_tag="VQ878_001258"
     CDS             10825..11814
                     /locus_tag="VQ878_001258"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET3095599.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(11887..12957)
                     /gene="xerS"
                     /locus_tag="VQ878_001259"
     CDS             complement(11887..12957)
                     /gene="xerS"
                     /locus_tag="VQ878_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET3095600.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(13451..15001)
                     /locus_tag="VQ878_001260"
     CDS             complement(13451..15001)
                     /locus_tag="VQ878_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET3095601.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(15017..15796)
                     /locus_tag="VQ878_001261"
     CDS             complement(15017..15796)
                     /locus_tag="VQ878_001261"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET3095602.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(15783..16634)
                     /gene="ylqF"
                     /locus_tag="VQ878_001262"
     CDS             complement(15783..16634)
                     /gene="ylqF"
                     /locus_tag="VQ878_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET3095603.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(16716..18224)
                     /locus_tag="VQ878_001263"
     CDS             complement(16716..18224)
                     /locus_tag="VQ878_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3095604.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTGKWKSVTVSYTKNTSRAR
                     KQAEREVLDKIDRLTTSFESQFSPELITTFGELKENWFQTWCVSVKPQTIQRELLVMK
                     RLGKIIGDDFLLDRITPLLMKKSLNKYLEIYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KFSPMTAVKLDISLEKRRKAKERHDSKFLEIHELHAFFDVLSQCRNANYYDLAIVLLL
                     TGIRISEAAFLPSDIDFEKGILHIDKALQYHCLKVEQFHFDTTKTLNSIREVALPEAA
                     SEAIKRTIQRNKEFDAYMEKHPCPAFTHSESVFRTEYGSPITSSTFRQILKRIEGKLL
                     TNCLSDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     INRSQENTVKALNQFVENHNFHFEELKSYTCKYSRIIEKFIETSDNSNKVEFSVDEFK
                     DLLHLSPRYSPKNIISNLLLKIKKDIVKYHPQFDIKIVKSSENQIRGFSIAW"
     gene            complement(18309..18542)
                     /locus_tag="VQ878_001264"
     CDS             complement(18309..18542)
                     /locus_tag="VQ878_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3095605.1"
                     /translation="MNIKYISVENSIAEWADKKGILKRWDGLNQYTLNRWIKEMRENR
                     TFSMYVINPTHKLVFINLEGFESFLRWKQKRTK"
     gene            complement(18812..19036)
                     /locus_tag="VQ878_001265"
     CDS             complement(18812..19036)
                     /locus_tag="VQ878_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095606.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSSYSKMEAGSRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            complement(19140..20969)
                     /locus_tag="VQ878_001266"
     CDS             complement(19140..20969)
                     /locus_tag="VQ878_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET3095607.1"
                     /translation="MVITKHFAIHGKNYRSKLIKYILNPSKTKNLTLVSDFGMRNYLD
                     FPSYEELVKMYNDNFLSNDTLYEFRHDRREVNQRKIHSHHIIQSFSPDDHLTPEQINQ
                     IGYETVKELTGGRFRFIVATHMDKDHIHNHIILNSIDQNSDKKFLWDYKSERNLRMVS
                     DRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRVYFLIENSKNFEDFKKKAKALH
                     LKIDFRHKHVTFFMTDSNMKQVVRDSKLSRKQPYNETYFKKKFVQREIINILEFLLPK
                     MKNMNELIQRAEFFGLKIIPKEKHVQFEFDEIKISEQELVKANRYSVSYFQNYFNNKN
                     ETVVLDNKNLVELYNEEKLIKEKELPTEEVVWKSYQDFKRNRDAVHEFEVELNLNQIE
                     EVVDDGIYIKVQFGIRQEGLIFVPNIQINMEEEKVKVFLRETSSYYVYHKDSTEKNRF
                     MKGKTLIRQFNLQYEPQYMYRRIPLSKIKEKIEQLDFLVSAENSQNAFEDITKDFIAQ
                     ISYLENMIDHVQNKIDDLSNLEEVLLNDATNSSSNLENSIQGKSSVDTIEKDLYIYKG
                     KIETLKEQHREAINLFEMFNKTIKKYKKKQNTKSIKENEIHLE"
     gene            complement(20956..21321)
                     /gene="mobC"
                     /locus_tag="VQ878_001267"
     CDS             complement(20956..21321)
                     /gene="mobC"
                     /locus_tag="VQ878_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET3095608.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLD
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEVELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
     gene            complement(21326..21682)
                     /locus_tag="VQ878_001268"
     CDS             complement(21326..21682)
                     /locus_tag="VQ878_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095609.1"
                     /translation="MKRDIRSIRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQISRDVHEVFIIAKTNHQVTHEHVSILLTCIQELIKEV
                     EKTGPLSEDFRNKYMR"
     gene            complement(21978..22268)
                     /locus_tag="VQ878_001269"
     CDS             complement(21978..22268)
                     /locus_tag="VQ878_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095610.1"
                     /translation="MNRKELYDDKLQLDYFSDSYLQFESDFYKYSALDIPLTFITDDI
                     LRTMAMSQKHYFKLNKSKSLDGRDHYFVFSIKMNKDSSGIRQYEYQRHCFNL"
     gene            complement(22258..22623)
                     /locus_tag="VQ878_001270"
     CDS             complement(22258..22623)
                     /locus_tag="VQ878_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095611.1"
                     /translation="MMNRSYLPFESARVYQDRGMAKWMGFFLSEHSSSLWAEKNKEDI
                     SISLSLEEKVLFVRQLYTNVFPATFVFKFSNQRKVVSGIVKEIGKEFISIKSDTGFLR
                     LKWEDILDIQIEGEELHES"
     gene            complement(22620..24035)
                     /locus_tag="VQ878_001271"
     CDS             complement(22620..24035)
                     /locus_tag="VQ878_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HET3095612.1"
                     /translation="MSWFDYSLEPQSDIAFIDMKSFYASVECVDRGLHPLKTSLCVMS
                     RADNSAGLILASSPMFKKVFGKSNVGRSYDLPFDVKTRKFSYYNARKQGLPTTIDYVR
                     YIEEWAKSTVIVPPRMDTYIAVNMEIQKIFQEFAAPDDIYPYSIDEGFIDLTSSLNYF
                     VPDKRISRKDKLDIISAAIQKKIWRKTGIYSTVGMSNANPLLAKLALDNEAKKTPTMR
                     ANWSYEDVEKKVWTIPKMTDFWGIGNRTEKRLHNLGIFSIKELAQANPDLIKKELGIM
                     GLELWFHANGIDESNVHKPYKPKSKGIGNSQVLPKDYIKQRDIEIILREMAEQVAVRL
                     RRSGKKATVVSIHLGYSKVEQKRSINTQMKIEPTNQTALLTNYVLKLFHTKYTSGAIR
                     NVAVNYSGLVDESFGLISLFDDIEKIEKEERLQSAIDAIRTEFGFTSLLKGNALDQAS
                     RTIARSKLIGGHSAGGLDGLK"
     gene            complement(24038..24721)
                     /locus_tag="VQ878_001272"
     CDS             complement(24038..24721)
                     /locus_tag="VQ878_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095613.1"
                     /translation="MFSPTKLKEKRESQGLSQSQLASSLGISRASYFNWESGKTKPNQ
                     NNLSKLSEIFNVDPRYFESEFEIVETYLKLTKKNQKATLHYATELLNKQNAKVVEIPE
                     RFAYKVYEKLSAGTGTAYFDDGNYDTVYFNRQFDYDFASWVSGVSMEPTYKNGSVALI
                     KQTGFDYDGAIYAIDWDSQTFIKKVYREENGLRLVSLNRNYPDKFAPYDENPRIIGKI
                     VGNFMPLED"
     gene            complement(24949..25719)
                     /locus_tag="VQ878_001273"
     CDS             complement(24949..25719)
                     /locus_tag="VQ878_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3095614.1"
                     /translation="MEIQDYTDSEFKHALTRNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPRYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKSKGYEVQLALIATKPELSYLSTLIRYEE
                     LYSINPNQARATSKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGEWNQVEKEMLKSGEERLKDLTNRNGL"
     gene            complement(25719..>25826)
                     /locus_tag="VQ878_001274"
     CDS             complement(25719..>25826)
                     /locus_tag="VQ878_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3095615.1"
                     /translation="TNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT         7818 a         4828 c         4811 g         8369 t
ORIGIN      
        1 tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa acctcaaatt
       61 gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg atgctgctga
      121 ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc aggcttataa
      181 agattattac gttcctatga acaaggctct ctggaaagac ttggagctga agaaaatcag
      241 taaacaagag ctggttaaca cgcgcttttc tcgtttattt tctcattttg gacaggaaaa
      301 agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg gacaaacact
      361 atcgggcgct catgatctct tggacagcct cattgagcgt gattataact tgtatgctgc
      421 gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc tagtacctta
      481 tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg ctctctttta
      541 tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga tgattggaga
      601 ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta tctggtataa
      661 tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct attcttacca
      721 agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt aaaggagatt
      781 agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa atgtctgaag
      841 ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa ttagcaaata
      901 gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc gatttaattt
      961 ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga agggattcac
     1021 aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact aatcgaaaat
     1081 atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac ttttttgata
     1141 tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat attaaagagt
     1201 attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt cgattttttt
     1261 ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa gtttctaaag
     1321 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
     1381 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
     1441 ttataaactg tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat
     1501 aaactgtaaa aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa
     1561 ggagtcggct atggaacact cgtcttggca tgctttgatt aaggcgcaat tacctgaggg
     1621 ttatttcggg aaaatcaatc agtttatgga gcaggtctat tctcagggga ttatttatcc
     1681 acccaaggaa aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt
     1741 aattctaggg caagacccct atcacggacc aggtcaagcg cagggcttga gtttttctgt
     1801 acctgactct atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga
     1861 tatcggagtt aagaaatctc atgatttgac atcttgggct gagcaaggag tcttgcttct
     1921 taatgcttgt ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga
     1981 gccttttact gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt
     2041 actctgggga gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat
     2101 tatcgaatca gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc
     2161 cttttccaag gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag
     2221 ataaggagaa aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact
     2281 gctcatgctc catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt
     2341 gggtggtaag ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga
     2401 agaaacaggg ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac
     2461 accagattta gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat
     2521 tgactgcaat gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac
     2581 ttgggaaggt gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc
     2641 caagtttgtt tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag
     2701 gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga
     2761 tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac
     2821 ggaagaagga gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga
     2881 tattcatgtg catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc
     2941 cctggcagcc gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac
     3001 catttcagac gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa
     3061 tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa
     3121 ggcgctctta gaagctggtg cggctggttt ctctgatgac ggtattccgc ttgagagcag
     3181 taagattgtc aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca
     3241 tgaggaagat ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca
     3301 tttccatatc tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat
     3361 gattgcctat gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt
     3421 taaagtagtg gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcgccaca
     3481 gcatttctct aagacagaag cacttttttt aacacaaggt agcaatgcta agatgaatcc
     3541 accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat
     3601 cacagttatt gcgactgacc acgcccctca tcatgtagat gaaaaaaatg ttgaggatat
     3661 taccaaagcg ccatctggta tgactggctt agaaacatcc ctgtctctca gcttgaccta
     3721 tttagtagaa gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc
     3781 agccaagctt tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac
     3841 tatttttgat gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa
     3901 ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca
     3961 aatcgtctat caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga
     4021 gacaagcgaa atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat
     4081 atgaaactaa agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa
     4141 gctattattg tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc
     4201 taagtttgaa aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga
     4261 agtatgtata agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc
     4321 ccaatcctga tttaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca
     4381 ggtcaataca acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct
     4441 ttctttacat ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt
     4501 ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg
     4561 ggcctatctg tggtattgct ggggatggta ctttttttgg caccaacaat cttgaatcat
     4621 attgggttag aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc
     4681 gggattatcc ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg
     4741 accaaactgt ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat
     4801 ctcttgattt acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga
     4861 acatccttgg cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag
     4921 aagctcaaag ccttacacct tgagaaacga attccactta atatggataa aattaaggaa
     4981 ggagttcgtt taggtctgcc tattggggga actgtcttcg cggaagtggc tatcttttca
     5041 gtggttggct tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct
     5101 atgaactttt caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt
     5161 gtcgtttcct atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta
     5221 ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg
     5281 ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta tcgatttgac agtgcgtttt
     5341 ttaacttata gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt
     5401 ttgcgggggt ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc
     5461 gtagcaatcc ctgtggctac gctatttgat tctctaacag attttggagc ttattcttac
     5521 tggatcggct tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact
     5581 gtgattatga agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa
     5641 atattcttga taagaaaatc ccttgttttc acggggtttt cttttttatt ttgtgaaatt
     5701 tcttttagaa aaactttgac agtatttgcc aaaaacggta aaatagtaag gtaagaagaa
     5761 agttagaaag gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt
     5821 aagatggaag aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa
     5881 gtgccaggaa tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta
     5941 gctctcaatc cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct
     6001 aaagggattg acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt
     6061 aaagggaaag gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat
     6121 ggtattgtag gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa
     6181 aataccggta aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc
     6241 cacgaagcag tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac
     6301 aacggttacg gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa
     6361 cgtagcgccg cttatggaat tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat
     6421 gtctatgaag gatttcagaa agctgtggac catgttcgca gtggcaatgg tccagtcttg
     6481 attgaaagtg taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt
     6541 acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac
     6601 cttattgaaa ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag
     6661 gaagcagtag aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca
     6721 gcctttgaag atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg
     6781 tccttccgtg acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg
     6841 ttcttgatgg gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg
     6901 cttgaagaat ttggtccaga acgcgtccgt gactgtccga tttctgaagc tgccatctct
     6961 ggagcagcag caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg
     7021 gacttctctg ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg
     7081 tttggtggta aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc
     7141 tctgccgccc agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag
     7201 gttgtggcac ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat
     7261 aaaaacccag ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca
     7321 gttgatccag actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat
     7381 gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta
     7441 gcagaagaag gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag
     7501 gatatcatca taaactcagt gaagaagact ggtaaggttg ttctggtcaa cgatgcccac
     7561 aaaacaagtg gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac
     7621 tatctagatg caccaattcg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa
     7681 aacctagaaa atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact
     7741 tataacaaag aatagagtta cataagataa gttatgtaaa taaaataaag ctgacgagaa
     7801 actttgtatc ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc
     7861 taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta
     7921 tttttcagtc gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga
     7981 tgacaagcta agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct
     8041 ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta
     8101 taaagacaca aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa
     8161 cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt
     8221 tttggccctg cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga
     8281 aaaagtggaa gaagtccctg ataacgtaac accatatggt gaaatcgagc gtattccaat
     8341 gacaccaatg cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac
     8401 cttcaccctc aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct
     8461 tgagccaatc atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc
     8521 agttgttaag actcttatga aacacccata catcaacgct tcattgacag aagatggcaa
     8581 gactattatc actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt
     8641 gatgacacct gttgtttaca atgctgagaa aatgagtctt tcagaactgg ttgtagcctt
     8701 taaggatgtt attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc
     8761 aacattcaca atcagtaatt tgggaatgtt tggtgttcag tcctttggtc cgattattaa
     8821 ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa
     8881 tggtgaaatt gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt
     8941 agatggtatg gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaacgccaat
     9001 ctcaatgtta atttaagagc aagagtattc atttttaaga tatagataaa ggaagacatg
     9061 gccttagaag taattatgcc aaaagccggc gtggatatga cagaaggaca aatcgtccaa
     9121 tggaataaaa aagtcggaga atttgtaaaa gaaggagaaa tccttttgga aatcatgact
     9181 gataaagtca gcatggaatt ggaagccgaa gaagatgggt acttgattgc cattctcaaa
     9241 ggagatggtg aaactgtccc tgtaacggaa gttatcggtt accttggtga agaaagggaa
     9301 aacatcccaa cagctggagc agcatcgcca gaagctagct ctgtacctgt agcaagtacc
     9361 tcaaacgatg atgataagag cgatgatgct tttgatatcg ttgtgattgg tggaggtcct
     9421 gctggttatg ttgcagccat taaagctgcc caattcggcg gtaaggttgc ccttgttgag
     9481 aaatctgaac ttggtggaac ctgcttaaac cgtggatgta ttccaaccaa gacctacctt
     9541 cataacgctg aaattattga aaatatcggt catgctgcaa atcgtggtat cgtgattgaa
     9601 aatcctaact tcactgttga tatggaaaaa cttttagaaa ctaaatctaa agttgttaat
     9661 actcttgttg gtggtgttgc aggacttctt cgtagctacg gagttactgt tcataaagga
     9721 attggtacaa tcactaaaga caagaacgtc ttggtaaatg gctctgaatt gcttgaaacc
     9781 aagaaaatca ttcttgctgg tggttcaaaa gtcagcaaga tcaacgtccc tggtatggaa
     9841 tctccacttg tcatgactag tgatgacatt cttgaaatga acgaagtgcc agaaagcctt
     9901 gttatcatcg gtggtggagt tgtcggtatc gaactcggtc aggccttcat gacatttggt
     9961 tcaaaagtga ctgttatcga aatgatggac tgtatagttc cagctatgga tgcggaagtt
    10021 tctaagaacc ttcgcttgat ccttgagcgt aaaggaatga ccatcttgac tggtactaaa
    10081 ctgcaagaaa tcattgagga aaatggtcaa cttcgtatca aggttgaagg aaaagacgat
    10141 atcatcgcaa gcaaagctct tctttcaatt ggtcgtatgc cagaccttga aggtattgga
    10201 gaggttgagt ttgaattgga tcgtggttgt atcaaggtca atgaatacat ggaaacttca
    10261 gttccaggca tttatgcacc aggtgacatc aacggtacta agatgttggc tcacgcagct
    10321 ttccgcatgg gtgaagtttc cgctgaaaat gcccttaaag gaaatcatgc aattgccaaa
    10381 ttgaatttga ctcctgcagc catctacact ctccctgaag tagcagcagt aggtttgaca
    10441 gaagaacaag cccgtgagaa atacgatgtt gccatcggta agtttaactt tgctgctaac
    10501 ggtcgtgcta ttgcatctga cgctgctcaa ggtttcgtaa aagttatcgt tgataagaaa
    10561 tacggagaaa tccttggtgt acacattatt ggtcctgcag ccgcagaatt aataaacgaa
    10621 gcatcaagca tcatcgaaat ggaaatcact gttgaggaaa tgctgaagac catccacggg
    10681 cacccaactt actctgaagt gatgtacgaa gcgtttgcag atgttctagg aatggccatc
    10741 cattcaccta agaaaaaata aaacgaagat agattagact ggaaggttat ttccagtttc
    10801 tatcatataa agtaaaggga tatcatgaaa tacattatca atcattcaaa tgacactgct
    10861 tttaatattg ccttggaaga atacgccttt aaacaccttt tggatgagga tcaaatcttc
    10921 ctactttgga ttaacaagcc atctatcatt gttggtcgtc accagaacac tatcgaagaa
    10981 atcaaccgtg attatgttcg tgaaaatggt attgaggtag ttcgccgtat tagtggtggt
    11041 ggagctgttt accacgattt aaataacctc aactacacga tcatctccaa agaagatgaa
    11101 aataaggcat ttgacttcaa gagcttctca actccggtta tcaataccct ggctcaactt
    11161 ggggttaaag ctgagttcac aggtcgtaat gaccttgaga ttgatggtaa gaagttctgt
    11221 ggcaatgccc aagcctatat caacggccgt atcatgcacc acggttgctt gctctttgac
    11281 gttgatttgt cagtcctcgc aaatgccctt aaggtttcaa aagataaatt tgaatcaaaa
    11341 ggtgtgaaat ccgtccgtgc ccgtgtaacc aatattatca atgaattacc aaaaaaaatc
    11401 acagtcgaaa aattccgtga tttactcttg gaatacatga aaaaagagta cccagagatg
    11461 actgaatacg tcttttcaga agaagaattg gccgaaatca atcgcatcaa ggatactaag
    11521 tttggaactt gggactggaa ctatggtaaa tcacctgaat ttaacgtccg tcgtggaacc
    11581 aaattcacta gtggtaaggt tgaagtcttt gctaacgtta ctgaatcaaa aatccaagac
    11641 atcaagattt atggtgactt ctttggtatt gaagacgttg ctgcagtaga agatgtcctt
    11701 cgtggggtga aatacgaacg cgaagatgtt cttaaggcgc taaaaaccat tgatatcaca
    11761 cgctacttcg ctggtattag ccgtgaagaa atcgctgaag cggtagttgg ataaatcaaa
    11821 aagaagttgg ccaactaacc aacttctttt tttgatattt atttacataa tttaaaatac
    11881 gtaaaattat aaactatcta gagcattctt ttgttcatca ttaacaatat gggtatagag
    11941 gtcagtgact tgtgtgctgg catgtcctag ttggtgactg actaaaactt gtgatttagt
    12001 cgcatcatag agcctagttg ctagcgtatg gcgcagttta tggggtgtta cacgcacttt
    12061 aaaatcctct gagtatttag caaccatttt ctcaacgcta gaagcatcga tacgattagg
    12121 aacacctctg tagagagtta aaaaaagggc tgtatctgtt ttttccgttt tatagcgttg
    12181 attccgaatg gccagataat tctctaaata aggtttagca aaagcagcga cattgactga
    12241 gtcacgtttg ccaccttttc gagtaacatc aataaccatc atttttagat tgagatctct
    12301 tagatctaga ttaacagctt cagataagcg aacaccagat gccaagagaa gggcaataat
    12361 ggctaaatct cgttctttat ttttgttgaa tgatgagaga gctcgatttg aaagctgttg
    12421 tgggtgctct tgatcgatat aagttagaaa acctgctgtt tcatcaccta gaaagagttt
    12481 ttgcttgata ttttcagctc tggcagcaag ggtttctttc tttttcttgg ttgaaacttt
    12541 tttcattaca ttacgataga aataaggttc cccctgatca ttttcaacct cctcggttag
    12601 atacttgtaa agactagaaa gtgctgataa ggttcgattg atagttgtct gtgaaacacc
    12661 ttgttttgtt gtattagcat tcagcaaggg acgttcacgt agataaagga taaaggattc
    12721 catgtctttc ttagacatat tttccaaaac tgataaagga atatcggata ttttatcagc
    12781 gtttgaaata ccagactcca aaacccagct gaaaaatcgg tcatattcct taaggtattc
    12841 gtacagggtt gtaaaactgt agggcacagc cagtttagat tggtagtatt ccagaacata
    12901 ccagggcatg agttgtttta gtttgtcgat tcgttccagt aaaatctcac gtttcatgta
    12961 ttttctccat aattaagtat actagtagta tagcatagac ttgtatattt ttcaagaaaa
    13021 ttatagtttt tcagaaagat gttataggag tttttcaaag tgataaaaag acttagacct
    13081 acaaacaaaa cagaataagg aaaataataa aaatctcacc cactaaactt ctgttaatac
    13141 tacatagcta gaaattgatt tgattgtcct gattgtttta tcctatttct atttcatttc
    13201 actatataat tgctattgtt ttctttttca tgattttaat cttactgtac agatttgata
    13261 cagtaaactc ctttctagct ttatgcttta tcatttctaa cttaattata gtcttatttt
    13321 taataaagtt caattattta tatgtaaaat tcctcatcag taaaaaataa ccgatctcat
    13381 ttctgagaat cggttttcta aataaatcaa accgatcatt tacataacat aaattatgta
    13441 aatgatcata ctacaacaac aaatctttga cttttccaat ttcacttttt ggaataacca
    13501 ggtgaatcat atcacccaga tacattctgg ttgagccgtt aactgtttgg ctcttgccat
    13561 tatggacttg agttgtgatg aggacgttgt gtggtaagtt gagttcatga acttgtttcc
    13621 cagcaatttt atcagaaact ggtatttcga taagtgtaac ttctccttcg ctagatactt
    13681 cttctggaag cattttttcc agcatggctt catagactgg cgtacctttg agcaaatcca
    13741 tgataatata agaaacaaga gtgacaagac caagtggcat aaggttgcga atatctccta
    13801 ccatctcagt tacgaggatc atagcggtta agggagcttt tgatatggct ccaaaatagc
    13861 cactcattcc tagaatgaca aatataggga attgctcttg actgacaagt ccaagattga
    13921 cacagataac accaactaag gcaccaagca aagaaccaag agctaaaatg gggaggaaaa
    13981 ttcctcctgg cagtccactt ccatagctaa tcatactcca aataaagcgg attaaaaagt
    14041 aagctaataa aacttggaaa ctaaaatttt gttcagttaa agaaaggaca agctgatttc
    14101 cgccaccaat gatttgaggt aagaagattc cgactggtat gataaggata aaagccaaga
    14161 tgggataata agccctatcc aaatggattt tttgaccaat caagtcataa actcttccaa
    14221 cgtttaatac agctttctca tagagaaaac ctgaaaatcc aaggaaaatt cccatgacga
    14281 gatatatcca atactggtct agggtcatgg gaggaatgtt atctggcata tccaatactg
    14341 gtgtcaaacc gaacatgagt agagacacaa agtttgctac gatgctggct gctagagttg
    14401 agacccagaa aaagcgcgaa aaatggtgat agacttcttc tacaacaaag agaagtgctg
    14461 caataggagc attaaaggct gcggctaaac ctgctgcagc tccactggca atcaaggaac
    14521 gttcctctac tggactggat ttgagccact tggcaattcc tttaccacca actgctccaa
    14581 gttgaatgct gggtccctct cgacccagca tgagtccact ggcaatagca agaataccta
    14641 gcacatattt tttccaaaga atgccccacc agttgaggga catgaggcct ttcagttcgg
    14701 cttcgacttg aggaattcct gagcctttaa tatctttttc tgaccgtgtt agtttggcac
    14761 tgagccaaca gatgagtata taaaacaaaa ccagtacaaa aagattgcgc actaagtacc
    14821 cttgatcttg ataaactcct tgtatcaggt ggaagccctt ttcaattaag aaacgaaagg
    14881 atccgacgat aattccaacg atgaggccga caatgattcc tcgaccaact tgggatagta
    14941 tagtgctgga tgcaaaggcg aattctttct tagaacggac tatttccgac tgttcctcca
    15001 tggtatttcc tttcaattaa ctttcttttt tacctaaaac cagtgattta acgggttcaa
    15061 agctggttcg gtgaattggg gtaactccta gttttgtgag gccttccaga tgtttagctg
    15121 tgccatatcc tgcattagta gcgaaatcat agccagagaa ctgctgatcg tattctttca
    15181 tcaattcatc acgtgttacc ttggctacta tagatgctgc tgcgatagag agggagttgg
    15241 catctccttt gataatggag gtttgtgaaa tgggcaagtc cagtttcatg gcatcaatca
    15301 aaaggtgctc tggttgaggg ctgagctggg agattgcttc ttgcatggct agtttggttg
    15361 cttcatagat gttgacttgg tcgatgacct gattatctat gataccaatt ccaatcgaca
    15421 aggcttggtc ttgaacggct tggaaaatct ccagatgttt ctttttagga attttcttgc
    15481 tgtcgttgag acctttaatc ttacaatttt taggtaaaat aacggccgca gcgactacag
    15541 gaccagcaag aggaccacga ccaacctcat caatacctgc aattaaggtc aatccttgct
    15601 tataaagttc tttttcataa gaaagcatgg attccaagcg caaattttca tctaattcag
    15661 cttgaatggc tcttttacgc ttgctgattt ccttttgaac tcctgagcga ttatcctttt
    15721 caagctctaa aaaaataggg ctttctaact ccttgactgt cacaaggagt tctttgattt
    15781 ctttaatcgt tgccatcgag gtcttccaat gtatctaagg tatagttacc gagtttgcca
    15841 tcacggactt ccttcacgaa gagactgtaa aaacggtcat agtcatcacg gaaaccgagg
    15901 gcgcgggtca tatccataat aatcacaggc gcttcttctt caattttcat ttgtttgaag
    15961 cgttcagcca gcttttctgg ataatgttct ttgaaataat tgataccaaa aatggtaacc
    16021 tcatccatag gaagcaactg atccttgata gctccagtca atgccaactt aagtgcaaca
    16081 gtttcatcct caaacttagg ccagagaatc cccggtgtat ccaagatttc cagatcttta
    16141 ttggttttaa gccattgttg accttttgtg acccctggct tgtttccaac aacagcaatc
    16201 tttttaccag ccaaacggtt catcagagtt gatttaccag cgtttggaat cccaataatc
    16261 atggtacgca aggtttcaat ctgaatccca cgttctttct ggcgagcaat cttatcagcc
    16321 atgagcttct tggccgcatc tgttacaact tttacagtca cttgctcttt ggagttgata
    16381 gctagcgtct ggattccttg tgattcaaaa tactgacgcc attccttggt cattgctgga
    16441 tcagccaagt cggccttgtt taaaatcaag agttttggtt tatcaccaac aatcttggtc
    16501 aacataggat tttgactaga tagaggcaag cgtgcatcta ctaaaatcgt cacaaaatca
    16561 acaaatttta aattttcctg cacctgtcga cgcgctttag acatgtgacc aggaaaccat
    16621 tgaatagtag ccattgagtt tttttccttt catagcaagg gtttagagcc cctattttat
    16681 tttactattg tctaaacacc aagcgaacac caaaactacc atgcaatgga aaaacctctg
    16741 atttgattct cacttgattt cacaatcttt atatcaaact gtgggtggta tttgacaata
    16801 tcttttttga tttttaatag taaattcgaa ataatatttt taggtgagta acgtggacta
    16861 agatgtaaca agtctttgaa ctcatcgaca ctaaattcta ctttattgct attatcacta
    16921 gtttcaatga atttttcaat tattctggaa tatttacagg tataactttt caattcttca
    16981 aaatggaaat tgtgattttc tacaaattga tttaaggctt ttacagtatt ttcttgtgaa
    17041 cgatttatat tatgtgtata gcccattgtt gtctcaaagt tagcgtgtcc tactctagtc
    17101 ataatatctt tcactgctat gtgcatctca ttactttgaa ggtaactaat atgcatatgc
    17161 ctaaacgaat ggggagtaac atgttttacc cacttaaaac catagtcact taaacaattt
    17221 gtcaataatt ttccttctat tcgtttcaaa atttgacgaa aagtgcttga tgttattgga
    17281 gagccgtatt ctgttctaaa tacactttca gaatgtgtaa aagcaggaca gggatgtttc
    17341 tccatataag catcaaactc tttatttctc tgtattgtcc ttttaatagc ttcgcttgca
    17401 gcttcaggca aagctacttc tctaattgaa ttgagtgttt tagttgtatc aaagtgaaat
    17461 tgttcaactt ttaaacaatg atattgaagt gccttatcaa tatgcaagat tcctttttca
    17521 aaatcaatat ctgatggtaa aaatgctgct tcactaattc gaatacctgt aagcaacaat
    17581 actatagcaa gatcataata gtttgcattt ctgcattggc ttaatacatc aaaaaatgcg
    17641 tgtaattcat ggatttctag aaatttagaa tcatgtcttt cttttgcttt acgccttttc
    17701 tctagtgaaa tatctagttt taccgcagtc ataggagaga acttaatgac attatataac
    17761 acaccatgat taaaaatctt attacaagta ctttttatat gagtcattgt tgaaggtgat
    17821 gcatcatata tttctaaata tttattgaga ctttttttca tcagaagtgg agtaatcctg
    17881 tctaataaaa aatcatctcc tataattttc ccaagacgct tcatcaccag tagttctctc
    17941 tgaattgttt gtggtttaac agagacacac caagtctgaa accaattttc ttttaactct
    18001 ccaaatgttg taatcagttc agggctaaac tgactttcaa atgaagtagt tagtctatct
    18061 atcttatcaa gaacctctct ttcagcttgt ttcctcgccc tactagtatt cttagtataa
    18121 cttacagtta ctgatttcca ctttcctgtt agtggatctt tgtacttttc aaccacttga
    18181 tataagggtt gcccttttga atttgtttta gttacataat acataattta attcctctta
    18241 actcttaaaa agaaataaat cattgttgta tagaataaat aactacccta tattatacca
    18301 tgacttcctt attttgtccg cttttgcttc catcttaaga aactttcaaa tccttctaga
    18361 ttaatgaaaa caagtttatg ggttgggtta attacataca tggaaaatgt tctgttttct
    18421 cgcatttctt taatccatct gttcaatgta tattgattta aaccatccca tctttttaga
    18481 attcctttct tatcggccca ttctgcaatg gaattttcga cagatatata ttttatattc
    18541 atgtcatcat ccttcctaaa aaatattttc acctccatgg catgactgat gaagtcatca
    18601 taagaatttc acttgctgct cttttacggt ggcagcctga acggtcagaa gtatcattgt
    18661 atatcatttg tatcatggca tataaagtat cgctctattt tattgatggt tttaatatcg
    18721 ctcttatcat ggcgagccat tcaaaactgc tccacaaatg aggaaagtac cattttggac
    18781 tattcaattg tcaatgtgct ttcttaacct actacttttt ggagtaatgg tcttctttat
    18841 tatccactcg acctacaagg tagtctagac tcaccttata aaaatctgca agtttgataa
    18901 ggtcatttat agagattagc ctgctaccag cttccatttt agaataagat gatcttgtac
    18961 aattcaaaac gattttcgca atatattctt gtgtcaaatc atcatcttca cgtaaatctc
    19021 taatcctttt caacatttgt tgtctcctaa aacaagtata atatagttat tttcttattt
    19081 ttaaatatgt gacaaattgg cacatgaaac tattctatat atacttttta ggaaactgtt
    19141 tactctaaat gtatctcatt ttccttaata gatttcgtat tttgtttttt cttatatttc
    19201 tttattgttt tattaaacat ttcaaataaa tttattgctt ctctatgttg ttccttcagt
    19261 gtttcaatct ttcctttata tatgtataaa tccttctcta ttgtatctac tgaactttta
    19321 ccttgaatac tattttctaa attgctagaa ctatttgtcg catcattcaa caatacttct
    19381 tctaaattac tcaaatcatc aattttattt tgaacgtggt caatcatatt ctctagatat
    19441 gatatttggg caatgaaatc cttggttata tcttcaaaag cattctgact attttctgca
    19501 gatacaagaa aatctaattg ttctattttt tctttaattt tgctaagagg aattcttcta
    19561 tacatatact gcggttcata ctgaagatta aattgcctaa tcaaagtttt acctttcata
    19621 aagcgatttt tttctgttga atctttatga tatacatagt aagaactagt ttctctgaga
    19681 aatactttaa ctttttcttc ttccatattg atttgaatat ttggtacaaa aataagtcct
    19741 tcttgtcgga taccaaactg taccttaatg taaattccat cgtctactac ttcttctatt
    19801 tgattaagat tcaactctac ttcaaactca tgaactgcat ccctatttct cttgaaatct
    19861 tgataggatt tccataccac ctcttctgtc ggcaactctt tttctttaat tagcttttct
    19921 tcattgtaaa gttcaactaa atttttatta tctaagacaa cagtttcatt tttgttatta
    19981 aaatagtttt gaaaataact aacactatac cgattagctt ttaccaattc ctgctctgaa
    20041 atcttaatct catcaaattc aaattgaaca tgtttttctt tcggaattat ttttaatcca
    20101 aaaaattctg ctcgttgaat caattcattc atattcttca ttttcggaag taaaaattct
    20161 aagatattta tgatttccct ttgaacaaac tttttcttaa aataagtttc attataaggt
    20221 tgttttctac tcaatttact atcacgtacg acttgtttca tatttgaatc agtcataaaa
    20281 aaagtaacat gcttgtgtct aaaatcaatt ttcaaatgta aagcttttgc ttttttcttg
    20341 aaatcttcaa aatttttcga gttctcgatt agaaaatata ctcgttgttt tatttcatat
    20401 ttgtaatttg ttttgcgata aacttcatac tgacgatgcg aataacgatt ttctataatt
    20461 tttgcccctg caatttttga aagacgatca gaaaccattc gtagattacg ttctgactta
    20521 taatcccata gaaacttttt atcagaattc tgatcaattg aatttaggat gatgtgattg
    20581 tggatatgat ctttatccat atgagttgct acgataaaac gaaatctacc tcctgtcaac
    20641 tctttaactg tctcataacc aatctgattg atttgttcgg gagtgaggtg gtcatctgga
    20701 gaaaaggact gaatgatgtg atgagaatga atttttcgtt gatttacttc tcgcctatca
    20761 tgacgaaatt cataaagagt atcattactt aaaaaattat cattgtacat cttcactagt
    20821 tcttcataac taggaaaatc taaataattt ctcattccaa aatctgaaac tagtgttagg
    20881 ttttttgttt tacttggatt caaaatatat ttgattagtt tactacgata attttttcca
    20941 tgaatcgcaa agtgtttagt gatgaccata aaatttcctc aatttttcag attgaataag
    21001 aaaatctttc tccacttcta ctattaactc ttctatacct tttctcaact catttaattc
    21061 aacttccgtt attaaattag aataatttat gctcctagct atttgattaa tattatttcc
    21121 tattcgtttt aattcaaaaa tcaaatcttg ataactattt gtatcaatgg tgataaaatt
    21181 cataccagga tctagtagag ttcgtctagc atattctgag aacgataagc agttactttt
    21241 tgagatattt tcattcaatt tgactaattc taggtcagat aaaaagacct tttttaaatt
    21301 tgttctatat cggtgctcca ctctactacc tcatgtattt gttacgaaaa tcttcactaa
    21361 gaggacctgt tttttctacc tctttaatta attcctgaat acaagttaac aaaatagaaa
    21421 catgttcgtg agtaacctga tgatttgttt tagcaattat gaatacttca tgaacatcac
    21481 ggctaatttg ttccaacttt tgttttttcc aaaggttgaa ccatttttcc atctgttttt
    21541 gtccatcaga taatagtaag cttttacgga gaaaatcaga aaaattatcc tctcctttct
    21601 ctctcattaa atctagtatt tgtttttctt ccgtttctgt taagcgaaat tgtttccgaa
    21661 tactacgtat atctcttttc atatgattta tcctctctca tagatacttg tactgacaat
    21721 gtaagcttac agacactgtc agtacgtttt acaaaataga ttcaacattt ttgtaaggct
    21781 ttgcgagctc agatattgtg tccacaatat cccaaaaatc atatcgcctg ccatttcaaa
    21841 cctcacggtt caaaaaacaa acgatatgac aatgtggtgg ctccgccccc aaacccccaa
    21901 gataaatcta aattaaaaaa agtataacaa atactttttg ataaaattat cacagaaaaa
    21961 agagccctgt cggactctta caaattaaaa caatgtctct gatattcata ctgtctaata
    22021 ccactactgt ctttgttcat cttgatagaa aaaacaaagt aatgatcacg accgtctaaa
    22081 gatttacttt tgttaagttt aaaataatgt ttttgagaca tagccattgt gcgtaaaata
    22141 tcatctgtga taaatgttaa tggtatatct aaagctgaat acttgtaaaa atctgactca
    22201 aactgtaaat aagaatctga aaaataatct agctgtaatt tatcatcata taattcttta
    22261 cgattcatgt aattcctccc cttctatctg tatatcgagt atatcttccc attttaatcg
    22321 aagaaaacca gtgtctgatt ttatagatat aaactctttt ccaatctctt taacaatacc
    22381 tgatactact tttctttgat tagaaaactt aaaaacaaaa gttgcaggga atacattcgt
    22441 ataaagttga cgaacaaata gaactttctc ttccaatgat agggaaatgg agatatcttc
    22501 tttatttttt tctgcccaaa gagaactgga atgttctgat aaaaagaagc ccatccactt
    22561 agccatgcca cgatcctgat atactcgggc agactcaaaa ggtaaataag aacgattcat
    22621 cattttagtc catctaatcc tccagctgaa tgaccaccaa tgagtttgct tctagcaatt
    22681 gttctagaag cttgatctag ggcattacct ttcaatagtg aagtgaatcc aaattctgtt
    22741 cgaatagcat cgattgcgga ctggagcctt tcttcttttt ctattttctc aatatcatca
    22801 aataatgaaa tcaatccaaa ggattcatcc actaaaccag aatagttaac cgcaacattc
    22861 ctgatagctc ctgaagtata tttagtgtga aataacttta aaacgtagtt tgtcagtagt
    22921 gctgtttgat tagttggttc aattttcatt tgagtattga tagaacgctt ttgttccact
    22981 ttagagtagc ctagatgtat agaaactact gttgcttttt taccagatct tctcaatcta
    23041 actgcaactt gttctgccat ctcacgaagt atgatctcaa tatctctttg tttaatataa
    23101 tcttttggta aaacttgaga gttccctatc ccttttgact ttggcttata aggtttatga
    23161 acgttgcttt cgtcaatccc attggcatga aaccataact ctagtcccat aatcccaagc
    23221 tcttttttaa tcaagtcagg attagcctga gccaattctt taatcgaaaa gatacctaaa
    23281 ttatgtaatc ttttctccgt gcgatttcca attccccaga aatctgtcat tttaggaata
    23341 gtccatactt tcttttcgac atcctcatag gaccaattgg ctctcattgt cggagtcttt
    23401 ttagcttcat tatcaagtgc caacttagct aataagggat tggcattaga catacctacc
    23461 gttgaataga ttcctgtttt tctccaaatc tttttttgaa tggccgccga aataatatct
    23521 aacttatctt ttcgactaat ccttttatca ggcacaaaat aatttaatga actggttaaa
    23581 tcaataaatc cttcatcaat tgaataggga taaatatcgt ctggagccgc aaattcttga
    23641 aaaatttttt gaatctccat attgactgca atataagtat ccattctcgg aggaacaatc
    23701 acagttgatt ttgcccattc ctctatataa cgaacataat ctatcgttgt cggtaaacct
    23761 tgctttctag cattataata agagaatttg cgagtcttta catcaaaagg taaatcatag
    23821 gaacgtccaa cgttcgactt tccaaagacc tttttaaaca taggagagga agcaagaatt
    23881 aaaccagcag aattatctgc acgactcata acacaaagcg aagtcttaag tgggtgtaat
    23941 cctctatcta cacattctac acttgcgtaa aaagatttca tatcaataaa ggcaatgtca
    24001 ctttgaggtt cgagactata atcaaaccaa ctcatactta gtcctctaaa ggcataaagt
    24061 tcccaactat tttccctata atgcgaggat tctcatcata aggcgcaaac ttatctggat
    24121 agttccgatt gagtgaaact aatctaagcc cattttcttc acgataaact ttcttgataa
    24181 aggtttgact gtcccaatct atcgcataga tagccccgtc atagtcaaat cctgtttgct
    24241 taataagggc tacagaacca tttttataag ttggttccat agaaacacca gatacccacg
    24301 atgcaaagtc ataatcaaat tgacgattaa aataaactgt atcgtaatta ccatcatcaa
    24361 agtaagctgt tcccgtacca gctgataatt tttcataaac cttataagca aaacgctcag
    24421 gaatttctac aaccttcgca ttctgtttgt tcaacaattc tgtagcataa tgaagtgttg
    24481 ctttttgatt ctttttagtt agcttgagat aggtttctac tatttcaaac tctgattcaa
    24541 aatatcgagg gtctacatta aaaatctcac tcaatttgct tagattattt tgattcggtt
    24601 ttgttttacc tgattcccaa ttaaagtatg aagctctact aattcctaaa ctagaagcaa
    24661 gttgagattg agataagcct tgactctctc ttttttcttt taatttagta ggtgaaaaca
    24721 tctcttctcc tttgtaagtt tattaactaa caaaagagta ccatagcttc ttgaaaaaat
    24781 caagagttta ataacaccct ggatttaaaa taatcataaa ctacaagaaa tcatcactga
    24841 agaatgctaa aacttttgaa aaaatttgaa gaagaaaata gagaatataa aaaaggatcg
    24901 ttatttttta attgacgatc caatagactt tattttaaaa atctaactct acaaaccatt
    24961 tcgattagtt aaatctttca atctttcttc tccagattta agcatctctt tctccacttg
    25021 attccattct ccaaatagta aatcatgaag aacggttgct gctgaagttg tattttcttt
    25081 tgaatcatat acacaacttc tatctcgttg ataaatttga attctttcaa aaatagctag
    25141 ttcttccaat tgccgtgtat tatcaactag atgatttaca atgaaatcat gatgttcttt
    25201 tgaagttgcg cgtgcttgat ttggattgat agagtacagt tcttcgtatc ggataagagt
    25261 actcagatag gacaattcgg gcttggttgc gattaaagct aattgtactt catatccctt
    25321 acttttcaag agttgtgctg ttttctttgg aacatcaatc gttcgtaaag ttccctctat
    25381 caaaagattg tatcccaaat gactcaattc tgttactaaa gactctacca ttttacctgc
    25441 aaaatctttg gtgtattcta cactatcttt gccatattct tgctgcagtt ctaaatagcg
    25501 tggatgctga gaacgaaaac tatcaccatc tatgataaca atatttcctt gaaattcttt
    25561 ctgtttaatc cgatgaattg tagttttacc ggcaccactt tgccctccaa gcaaaatcgc
    25621 tataggttgc ttactggact tttttcctct tgtcagtgaa cgaagattcc gtgttagagc
    25681 atgtttgaat tcactatcag tataatcttg gatttccatt aggctaccat ccgtttttca
    25741 gatatctcta acatacgttc aattccatcc aaatagccgc tatacctctc tatttcatca
    25801 aaagtttcta ctaaatagat attcgt
//
LOCUS       DAVBOM010000029        25643 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBOM010000029 DAVBOM010000000
VERSION     DAVBOM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25643
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.029"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..163)
                     /locus_tag="VQ878_001275"
     CDS             complement(<1..163)
                     /locus_tag="VQ878_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3095616.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDR"
     gene            complement(144..329)
                     /locus_tag="VQ878_001276"
     CDS             complement(144..329)
                     /locus_tag="VQ878_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095617.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(633..2195)
                     /gene="guaA"
                     /locus_tag="VQ878_001277"
     CDS             complement(633..2195)
                     /gene="guaA"
                     /locus_tag="VQ878_001277"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET3095618.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2337..3035
                     /locus_tag="VQ878_001278"
     CDS             2337..3035
                     /locus_tag="VQ878_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3095619.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3078..3974)
                     /locus_tag="VQ878_001279"
     CDS             complement(3078..3974)
                     /locus_tag="VQ878_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3095620.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3983..4918)
                     /locus_tag="VQ878_001280"
     CDS             complement(3983..4918)
                     /locus_tag="VQ878_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET3095621.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4915..5640)
                     /locus_tag="VQ878_001281"
     CDS             complement(4915..5640)
                     /locus_tag="VQ878_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET3095622.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(5724..6359)
                     /locus_tag="VQ878_001282"
     CDS             complement(5724..6359)
                     /locus_tag="VQ878_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET3095623.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6361..7188)
                     /locus_tag="VQ878_001283"
     CDS             complement(6361..7188)
                     /locus_tag="VQ878_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3095624.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7210..7545)
                     /locus_tag="VQ878_001284"
     CDS             complement(7210..7545)
                     /locus_tag="VQ878_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET3095625.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7546..8077)
                     /locus_tag="VQ878_001285"
                     /pseudo
     CDS             complement(7546..8077)
                     /locus_tag="VQ878_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8708..9319
                     /locus_tag="VQ878_001286"
     CDS             8708..9319
                     /locus_tag="VQ878_001286"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3095626.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9364..10092
                     /gene="rlmB"
                     /locus_tag="VQ878_001287"
     CDS             9364..10092
                     /gene="rlmB"
                     /locus_tag="VQ878_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET3095627.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(10131..11042)
                     /gene="trxB"
                     /locus_tag="VQ878_001288"
     CDS             complement(10131..11042)
                     /gene="trxB"
                     /locus_tag="VQ878_001288"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET3095628.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11108..11332)
                     /locus_tag="VQ878_001289"
     CDS             complement(11108..11332)
                     /locus_tag="VQ878_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET3095629.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11410..12153)
                     /locus_tag="VQ878_001290"
     CDS             complement(11410..12153)
                     /locus_tag="VQ878_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3095630.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12153..12953)
                     /locus_tag="VQ878_001291"
     CDS             complement(12153..12953)
                     /locus_tag="VQ878_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3095631.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13111..13467)
                     /locus_tag="VQ878_001292"
     CDS             complement(13111..13467)
                     /locus_tag="VQ878_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET3095632.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13480..13992)
                     /locus_tag="VQ878_001293"
     CDS             complement(13480..13992)
                     /locus_tag="VQ878_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET3095633.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(13992..14486)
                     /locus_tag="VQ878_001294"
     CDS             complement(13992..14486)
                     /locus_tag="VQ878_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095634.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14621..15067
                     /locus_tag="VQ878_001295"
     CDS             14621..15067
                     /locus_tag="VQ878_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET3095635.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15064..15711
                     /locus_tag="VQ878_001296"
     CDS             15064..15711
                     /locus_tag="VQ878_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET3095636.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15732..16313)
                     /gene="pdxT"
                     /locus_tag="VQ878_001297"
     CDS             complement(15732..16313)
                     /gene="pdxT"
                     /locus_tag="VQ878_001297"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET3095637.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16314..17189)
                     /gene="pdxS"
                     /locus_tag="VQ878_001298"
     CDS             complement(16314..17189)
                     /gene="pdxS"
                     /locus_tag="VQ878_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET3095638.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17341..18720)
                     /locus_tag="VQ878_001299"
     CDS             complement(17341..18720)
                     /locus_tag="VQ878_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET3095639.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19014..19937
                     /locus_tag="VQ878_001300"
     CDS             19014..19937
                     /locus_tag="VQ878_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET3095640.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19997..20602
                     /locus_tag="VQ878_001301"
     CDS             19997..20602
                     /locus_tag="VQ878_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3095641.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20621..21865
                     /locus_tag="VQ878_001302"
     CDS             20621..21865
                     /locus_tag="VQ878_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3095642.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22088..22345)
                     /locus_tag="VQ878_001303"
     CDS             complement(22088..22345)
                     /locus_tag="VQ878_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET3095643.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22387..24423)
                     /locus_tag="VQ878_001304"
     CDS             complement(22387..24423)
                     /locus_tag="VQ878_001304"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET3095644.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEYFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24683..25600)
                     /gene="glyQ"
                     /locus_tag="VQ878_001305"
     CDS             complement(24683..25600)
                     /gene="glyQ"
                     /locus_tag="VQ878_001305"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET3095645.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEILLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         7599 a         5768 c         4668 g         7608 t
ORIGIN      
        1 agcggtcttt acgtccacca caaaagagaa aaacttgacc ggagaaagga tctaattcaa
       61 agtgggtttt aaccagataa gccagtgaat caatgccttg cctcatatcc gttttcccac
      121 atacgagata gacctgccct aggctagata gatgaattgt catagagcaa caccttatcc
      181 aaaagctgtt ctaccatttc gagattgaga gattgaaaaa aacttacttc aagcttgcca
      241 atacgaattt taagcagaat atcatttctc tttttagaat caaaaggacg agattgtgga
      301 atctctacag gaacaatagg ttgtggcatt aaaatatcct ccaatagttt tactttacta
      361 atagtataca ggaggagctc catgaatgat agataccttg ttatgacgcg cttaccatat
      421 tagaaagttg gctctctaat taaattaatt ctcattatat atatcaaaag accgcagttt
      481 gaaaactacg gtctaatttt ttgtccaaat gtaaaccact tggaactatt attcaattta
      541 ttctttttag caaatgttcc cgttttaatc ccagttacag tttttaatcc tttgtaaccg
      601 ttgattttac aaagctttta atttttttgc gattactccc actcaactgt tgcaggtggt
      661 ttacttgtaa tatcgtagac gatacggtta acatgatcca cttcatttac gatacgtact
      721 gagatttttt gaagtacttc ccatggaatt ttggcaaaat cagcagtcat accatcgata
      781 gaagtgatag cacggattgc aatcgtgtag tcatacgtac gaccgtcacc cataacaccg
      841 actgaacgaa cgcctgtgtt aacagtgaag tattgccaaa tatcgcggtc aagtccagct
      901 ttagcgattt cttcacgaag aatagcgtct gattcacgaa cggtttcaag tttctcttca
      961 gtgatttcac ccatgacacg gatagcaagt cctggtcctg ggaatggttg gcgccatacg
     1021 atatggtctg gcataccaag ctctgtacca agagcacgaa cttcatcctt gtaaagagta
     1081 ttgagtggtt caatcaattc aaactgcata tcttctggaa gaccacccac gttgtggtgt
     1141 gacttgatag tttgagctgt atccgtacca gactcgataa catctgtata taaagtacct
     1201 tgagcaagga atttcacatc tttgagcttg cttgcttcgt catcgaatac atagacaaac
     1261 tcgttaccga tgattttacg tttttgttca ggatcagaaa cgccagcaag tttgtcaagg
     1321 aaacgtttag cagcgtctgc tttgacgata ttcaaaccaa acttaccacc gagcatgtcc
     1381 ataacttgat cagcttcgcc tttacgaaga agaccgtggt ccacgaagat acagatcaat
     1441 tgatcgccaa tcgctttttg gagaagaacc ccaacgacag atgagtcaac accacctgat
     1501 agaccaagaa ggacacgttt atcaccgacg gtttcacgaa tttttttgat ctgcatgtca
     1561 atgaaattat ccattgacca gtcaccttta gccttacaaa tgttaagggc aaagttacga
     1621 aggatatcat ttccgtatac agaatgacga acttctgggt ggaattggat accgtaaatg
     1681 tgtttatctg ggttttcgat ggctgcgtat gggcagtcag ctgatgtacc tgtacgaaca
     1741 aagtcagcag gaatctcagt aaccgcatca ccatggctca tcaaaacagt ctgttcatca
     1801 ggtgttgatt caaaaagcgc tgatggtgtg tgagttaggg ttgattgacc gtattcacga
     1861 tttccagcat cacctgcagg aacaactttt cctccaagtt tatgggtcaa taactgcata
     1921 ccataacaga ttcccaaaat tggaattccg agttcgaaga tttctgggtc aatatcaaat
     1981 gaaccatctt catatacaga atttggacca cctgatagaa taattcctac aggattgact
     2041 tcacgaactt cagcagctga aattttatgg ctttttagtt ctgaaaaaac accaatatca
     2101 cggatacggc gtgaaatcag ctggttgtac tggctaccat agtccaatac gatgattttt
     2161 tctacatctt gcaaatcagt tgaaatgttg ctcatctttt tcctttctca aaagaaatat
     2221 cttttctcaa tattctatca caaataaggg cgaattacca actaaacaag gcgaagtttg
     2281 actttttcta gtttattggg gtacaataga gaaaagatag aaatgaagtg aaaaatatgc
     2341 tacctgctta tatgaaaatc catgatcaga taaaaaagga tattgacgag caccgttggg
     2401 ctattggtga gaggcttccc agtgaaagag atttagctga gcagtttgcg gtcagtcgca
     2461 tgaccctccg ccaagccgta tctctattag tcgaagaagg cgtcttagag cgccatgtag
     2521 gaagcggcac ctttgtttcc agtactcgag tacaagaaaa gatgcgaggg acaaccagtt
     2581 ttactgaaat tgtcaaatcc caaggtaaag ttccctctag ccagctcatt tcctacaaaa
     2641 aaaccattcc caatgagcaa gaagttgcca agctaggaat ttttccaacg gacaatatta
     2701 tccgaatgga gcgggtccgc tatgccgacc aagttcccct agtttatgaa gttgcttcta
     2761 ttcctgaaaa attcattaag gactttaaaa aagaagaaat caccagtcat ttcttccaaa
     2821 ccttgcaaaa acatggctat cgtatcggca aatctcaaca gaccatctat gctcgccttg
     2881 ctaaagaaaa gattgcccac tatttggaag ttgaaaaagg acatgctatt cttggattga
     2941 cccaggtttc ctacctagaa gatggtactg cttttgaata cgtaaaaagt caatatgtag
     3001 gcgaacgctt tgaattttat cttgaaaata attagattac cacgcaaaaa ctctctgtca
     3061 cggacaaaga gtctttttta tttttctaag aataaatctt tcaaagaaat caaagttaca
     3121 gcaaacaata tcattgccat accaagaaaa tcaatgggat aaaattgttc attcattatt
     3181 aagaaggcaa agaaaatcgc cgatattggc tcaattgaag ccaacaagct tgacttgacc
     3241 ggtcctatca gactggctcc tttaaggaaa gctgtatagg caaagacagt cccgataagg
     3301 ataatgcctg caaacgcaag gagaaaatca agactagtcg ggatatcggc ctgtagaacc
     3361 cctgtaaaag gaagagcgac caaacctgct atgaccattc ccacaccaat gaccaagctg
     3421 ctcccccact ttttaatcaa ggctatgggt aaaatgatat acagagcata agtaaaggca
     3481 gaaaagagac cccagaacag accagcaggt gtcatggata actggtccaa ctgcccatgt
     3541 gttgcgatca ggaaggttcc tccgatggcg aatatgatgg aaactatctc tcccagtgtc
     3601 ggtgccaccc tatccttgat acagctataa attaaaattc cgacaggaca aacatactga
     3661 agcaccgtcg ctgttcccgc attggtctcc tgaatagcag acagataggc gaattggttg
     3721 agaaaaagac caatcagagc aaaaataaga agagacagca aactctttct atcctttaaa
     3781 aagaccagta ttttatcctt tgcagtagca taagccaaga gcatgagaat tccaccagcg
     3841 attaaaagac gcaagttggt caagaccaga gccgaaattc cgtgtgccat taggtattgg
     3901 ccactcgttc ctgacaaccc ccaagcaata ccagccacaa ctgttagtaa agtccctttt
     3961 aaactatttg acatgtctct ccttactctt ctttgcgaat caagttcatc acttgattgc
     4021 ggtctaatat ccattgagct ctctcgtcct tttcataggt acgattcgat aggaaaatag
     4081 tggcttcttg cttctgacga ttccacatga taaaggtacc tgtatagccc gtatggtcta
     4141 gccaatctcc ttccaaattc catgctaaag aacgttcctt gtcatccaaa ggagaaaaat
     4201 tttgacttaa gtctcttgca aaatcatctg ctaaatagtg ttctaaaaag atttgtaaat
     4261 cctttatagt cgaaaataaa ccagcactcc cagcatgtct acccaggaga cgagccttgg
     4321 gatcatgcac tatgcctgcc tctacacctc taactgttgg aacagcaagc tcaactgacc
     4381 caaacttggt ttccgtcatt ccccaaggtt tccagacttg atcctttaaa atcacatcca
     4441 aatcttgatt aaaaattctt tccaaaataa agcccaacag caaaaaatgg acatccgaat
     4501 aaagaaaggc tggctgactt cgtctgttga gatgaaacat cgcttccttt aattcagggg
     4561 ctgttaaaag atcacgatta ggaataaaag gatcaaggtc tgttgcatga gtcaagagct
     4621 ggcgaatagt gatgtctgga taatcactct caggtaaaaa atctattacc agtctatcaa
     4681 tatctaattg acctatttcc cacaagaagg tacaaactgt gccaacccca acaaccttgc
     4741 tgacactagc taggtcataa actagtcctg cctcagtctg caagccatgc tctgggtcac
     4801 tctggcctaa atagaactct gtccattgat tgtccttaaa atacgcaaaa gaggctccgg
     4861 gataaattcc tgcctcgatt tgttcttcta tttttttaat aatcttggtc cacttcatac
     4921 ttcttcaaac cacaattcaa cattatttct atctttacaa aggaagaatt tttcagactt
     4981 aggaataaaa tattcagtag actcaaactt ctggcgaaga cttgctatgt ctaattcatt
     5041 gaccaagaac ttgagcatag ataagtccca ggtaaccgta ttgtccacag tcaaatcctg
     5101 cccctgagct ggaataaaat caagggatgc cccaatttca gatgattcca agaaactttc
     5161 gatatcagtt gggagatgta attccataga aatctcaaat ttacttaaag aaattgatac
     5221 caaatctgtt tgaaattcag gcttttctcc tacttctact agacttgctc tgtcatcttc
     5281 cgcatgaatc aaaatcaaat catcttctgg tgagaaaatt tcaaaagcgt agccattttg
     5341 acctttatat aatcgatgaa tcgaatctgt tttagataag attccttcaa tttctaaggg
     5401 attttccacc ttgacaatca atctagctag tttttttctt ccctctacct tacgagtacg
     5461 catactggga gcttcttcta aaaccagctt ttcaagaccc gtttggtcac ctagtgacag
     5521 aaaggccgat tcttctaaca aggccttcat tccaagggtt tcaatataaa atgtttcatt
     5581 taattttcta ttattagctt ttaaagtagg aataatccgt acaatctgat ttacattcat
     5641 aaattcctcc gtcacttttt attttaaagg attttagaat tttttacaag atattatgct
     5701 caaatttaac attatttagc tatttagtaa agatagtctt tcaaggcttt tgacaaagcc
     5761 tgataaccag caatactgag gtgcagtcca tcagttgtat attctttttt gagttggcct
     5821 gcttggtctg tcaaacaatc aaatactggc acaaattcca cctgcatata ggcagatgca
     5881 agctcttgat aggcttgatt ccagttctga attttttcat tcgagcggat atagactgcc
     5941 tgctggtact cctctccctc attgacaggc aaaatggaaa gcaatttaat ctctgtcaat
     6001 ggataatcgc gagcaacgga ttgaatgata gcttcgagat tattgagagc ctcattcaca
     6061 ggaacatcct ttccgatatc atttgtccca atcagaagaa aaattttatc tactgctcca
     6121 ccatatagat gagcatcaag gttctctagt aacagtcctg tctgatagcc acgaattcct
     6181 cgattgacaa tcgtctttga agtcccaaat agctcctgta gaggataata ctcgacaatg
     6241 gaatccccaa taaaaagaat gtttggttct acaacagaaa tgtgatttag gtgacgatac
     6301 ttagtttgaa ttttttcttg ttcctttagg agccaatttt ctaataactg tactgccact
     6361 tcattctcct ttttctaacc agttttccaa gacttgataa actcctcctt ggctgttggc
     6421 tggtgctaga gcagtcgcca cagctttggc tttctcatca gcattttcca tcgcataggc
     6481 aattccagcc atttcaagca tttcaacatc attttcacta tcaccaaaag ccatgatttc
     6541 ttgggatttc aagtcccagc gcttgagtaa ttcctccaag ccccatgctt tatgaatccc
     6601 agcttggagg atatcaatgc aaccatagcc actggataca gctcggacac ggccatcaaa
     6661 gagagcattg atttcttcca aaaccgaact caaacgttcc tcaccaacaa ccatgctcat
     6721 cttgagcaca ccaccaaaga ggtcagatgt taattcatcc acaaattgca tccgttggta
     6781 gaatttttca atcatttctg gagtcataaa actttcaaga tctgtaaaaa tcgtaccttc
     6841 cttgacaaaa tcacccttca tccccgttac aacaaactgg tcctgacacg ctcgaccctt
     6901 gaaatgagtc aaagccttgt tgacaatggc gtcatcccat gtctgagcct gaatcaattc
     6961 attgttttca aaaatacgag cgccattagc aacaaccaga accactcgat ccaccaaggg
     7021 actcagtagt tgtctcatgc ggtgaatttc attgcccgtc gcaatgacaa aacgaatgcc
     7081 cctttgatcc aactgatcta aaatcttttc caatcgtggg agatcaagct gacctctagc
     7141 atccagcaag gtcccatcca tatctgtcgc aattacctta atcatcattt actttcctct
     7201 ggattcaagc taataccact tcaatcccac atgttcattc atttctttat aggctgtatc
     7261 aattcgttcc ttagtcgctt catctaactg gtcacgatga ctgccatcct ctataaaatc
     7321 ttccaaaata taagtttggt aatgatacaa gggatatcct tctggtgaaa aggttccctt
     7381 tggtgttcga ttgacccaag taggatgagc tttagctgtt ccgatagttg tttttccatc
     7441 cttcttcttg atggtgacat ccatgagaac accacgttca gtccacttag cattctcttc
     7501 atctcccata gattcaatcc gttgattgga aatgaagttc cccatttaat agacaatgag
     7561 cttcttatct ccatcttttt ccaccgtttc agatggttca acaacgtgag gatgccctcc
     7621 aaagataata tccgctcccc aatcgatcat cttgtgataa agagcttttt gttcttcagt
     7681 tggttccaat cgatactcaa cacccatctg aagcatgata atggtgatat ctgcttcctt
     7741 ctctgcccgt tcaatttcaa ccttcatctt atcttcgttt aaatctgaaa gataacgatt
     7801 atagtcttcc tgagaaatat actgctcaat tccattgaaa ccataggaat aggctaacaa
     7861 tgcaaccttg ataccattca cttccttaat gaccagcgga gcctgaacac gtggttcgtg
     7921 cgtataaact ccgattggag tgattccagc tttctcaata atatcggccg ttgaaataac
     7981 tccctcaagt tgaaataact ccctcaagtt gcgaatccaa aatatgatta tgagctaaat
     8041 ccagcacatg ataacctgcc tccttaatag catccataac ttcagcagga gcattaaaga
     8101 gaagataacc cgctaaataa tgatccttat taatggttcc ttcaaaatca ccaatagcta
     8161 aatctgcttg cttgagccaa ggagtcacat actcaaaatt ttcatgaaag tcataggtac
     8221 cgtcttcttt tttagctgaa aagaaaagtc catcgtggta gagcaaatcc ccgtgggcca
     8281 taattctggc agttttttcc tcttcctact cctgagactt ttgcttagtc ccctcttgag
     8341 aaatagtatc tcgtttttga ctagtcaagg gattccttgg aagctttcaa acaacaagac
     8401 caagcccttc ataaaacgaa aagctaaacc accctgattt cgattttatc ttctttgtat
     8461 cttcattctc cctactttct tatgcaagcc ttttcttttt attatatcac agataagtat
     8521 ttctttcaca attgaattga acttcccatc tattttctat aaatcctaaa tgccataatg
     8581 ctttcaattc ttgtcatttt gtgatatcat gtagaggaaa tgaactaatc cacagtggct
     8641 tatttcaagt ataccacttg ggctttggca gtagctaact gcactaaata taatataagg
     8701 agagaaaatg tctgcaatag aacgtattac aaaagctgct cacttaattg atatgaacga
     8761 tattatccgt gaagggaatc ctactctacg cgcgattgct gaggaagtca ctttccccct
     8821 atctgaccag gaaatcatcc taggcgaaaa gatgatgcaa ttccttaaac attcccaaga
     8881 ccctgtcatg gctgaaaaaa tgggactccg cggtggtgtt ggactggctg ctccccagtt
     8941 agatatctca aaacgcatta tcgctgtttt ggtacctaat attgttgaag aaggcgaaac
     9001 tccacaggaa gcctacgatt tggaagccat tatgtacaat ccaaaaatcg tctctcactc
     9061 tgttcaagat gctgctcttg gcgaaggaga aggttgcctg tctgttgacc gtaacgtgcc
     9121 tggctatgtt gttcgccatg cccgcgttac tgttgactac tttgacaaag atggagaaaa
     9181 acaccgtatc aaactcaaag gctacaactc cattgttgtt cagcatgaaa ttgaccacat
     9241 taacggtatc atgttttacg atcgcatcaa tgaaaaagac ccatttgcag ttaaagatgg
     9301 tttactgatt cttgaataaa gaaaatcccg ttgcaagacg gggttttgtg ttataataga
     9361 ggcatgaaaa caaatgatat tgtctatggc gtccacgccg ttaccgaagc cctccttgca
     9421 aatacaggaa acaaactcta cctccaagaa gatctccgag gtaagaatgt tgagaaagtc
     9481 aaggaactag ctacagaaaa gaaggtgtcc atttcttgga catcaaaaaa atctctctct
     9541 gagattactg aaggtgctgt tcatcaaggt tttgttctac gagtgtctga atttgcctat
     9601 agcgagctag attacatcct tgcaaaaaca cgccaagaag aaaatccact tctattgatt
     9661 ctagatggtc taaccgatcc ccataatctg ggttctatct tgcgaacagc cgatgcgacc
     9721 aatgtttcag gtgtcatcat tcccaagcac cgtgctgtcg gagtaactcc tgtcgttgcc
     9781 aaaacagcca caggtgctat tgaacacgtt ccaattgccc gagtgacaaa cctcagtcaa
     9841 accttagata aactcaagga tgaaggcttc tggacctttg gaacggatat gaacggtact
     9901 ccttgccaca agtggaatac aaaagggaaa atcgccctca tcatcggaaa tgaaggaaaa
     9961 ggcatctcta gcaacatcaa aaaacaggtc gatgaaatga ttaccattcc gatgaatgga
    10021 catgttcaaa gcctcaatgc cagtgttgct gcggccattc tcatgtacga agtttttcta
    10081 aatagactat aaaaaagttt ccagtcatct gattggaaac ttttttataa ttaactatgt
    10141 tctgtgataa acttgtaggc ttcttgacca gcgatagctc catctccaac tgctgttgtt
    10201 acttggcgaa ggtctttcaa gcgaacatct ccaactgcaa agataccgtc gactgcagtc
    10261 ttcatgtggc tatcagtcac aatccagcct gcctgatctt ggatattcaa ttctttaaca
    10321 aaatcgctaa gagggtccaa accaacatag ataaagacac caccgaaggc ttgctctgtc
    10381 acttgacctg ttttcacatt ttcaaaaacg acagattcta ctctgttttc acccttgatt
    10441 tccttcacta cagaatccca gataaagctg attttttcat tcgcaaaggc gcgatcttgt
    10501 aaaacctttt gggcacgaag ttggtcacga cggtgaacaa tggtaacagt cttagcaaaa
    10561 cgagtcaaga agagggcttc ttcaacagct gaatctccac caccaactac caataaatct
    10621 tggtcacgga agaaagcacc atcacacaca gcacagtaag aaacaccacg actgttcagt
    10681 tcttcttctc caggcactcc caaaggacgg tgtttagaac cagttgctac gataactgta
    10741 cgtgtttcat atgtttggtc atcagtcatc actttcttaa aatcaccatg gtcttcgaca
    10801 ttttcaacat aaccataaat gtgctcaaca ccaagatttt caagtggttc aaacatcttt
    10861 tcagccaatt caggtccact aatattagcg tatcctgggt aattttcgat atcagatgta
    10921 ttattcatct gaccacctgg cagaccacct tcaatcaaag ctacttttag attgcttcga
    10981 gcagcataca aggccgcagt catccctgca ggtccagcac cgataataat agtatcgtac
    11041 atatagattc cttctttctt gttgtaacta tctttattct aactctttct tgtcaatcac
    11101 gcaaggatta tgccttgaaa acaagaatta aactcataac cgcaaaggat aatactggga
    11161 caaccaagac tccaatcata atcatatcat agagatgggc ttggcgagcc ctggctgtct
    11221 tatcaactcc cgacatggct ctcagaccaa tccaaatccc taaaaaaatc agaacaagga
    11281 tggtggtcaa gatcaaactc tcgaaatata aagaaaatag ttgcagtagc atgatttctc
    11341 tcatttctat cttttttaaa gagtaaactc agctagtcca actaactgag ttttccttta
    11401 tctattatat caaatataag tccgtttgta actagcgaag aattcttttg tccgctcttc
    11461 tttaggggtg tggataatct catccggagt tccagactcg atgattttcc ccttatctaa
    11521 gaagagaatt ttatccgcaa cttgggctac aaaggacatg tcatgactga ccaaaatcat
    11581 ggtctgacct gacttagcag catctgcaat agacttttct acttcaccga ccaattctgg
    11641 gtcaagggct gaagttggtt cgtctaagag caaaacatct ggtttcatag caagcgcacg
    11701 cgctagggca acccgttgct tctgtccacc tgataaatgg cgaggataat ggttttcacg
    11761 gtccgaaagc ccaaccttag ccaactcttc cttggcaatc ttagtcgctt cttggtcaga
    11821 taatttcttg acaacaacca agccttcttt cacattatca agtgctgttc gacgttcaaa
    11881 taaattaaac tgttggaaaa ccatagacaa cttacggcgt agggcaagga tttcttcttg
    11941 agtgatttta gaaaaatcaa ctgaaaaacc atcaatctga atagagccac tgtcaggtgt
    12001 ttcaagataa ttgagactgc gaagaaaggt tgattttcca gctcctgaag aaccaatcaa
    12061 ggctacaact tccccttttt gaatatccaa gttcagatga tccaagacag tctgtcctga
    12121 aaaggatttg cttaaattcg aaatcttaat cattaacgaa ggtctccttt cacatctgtt
    12181 tgcactgtat caggtgcaga aatagccatt tttctctcga tgaaacgacc gaggctttca
    12241 attccgatat tgactaccca ataaacaagg gcaacagaga tgaagcgttc aaaatagcga
    12301 taatcagctc cacctagaat ctgagcttgg gcaaagactt ccacaacacc cgcactaaaa
    12361 gctagagatg ttcccttggt caaaccgatg agggaattaa tcaaggttgg agtagctacc
    12421 accgctgcat taggaataat cactcgtcga taaacttgcg ctcgggtcat acccagactg
    12481 cgcgccgcct caatctcacc aggattaact gagagaatgg ctgcacgaat ggtttcacta
    12541 gcataagctg cctcattaaa ggcaaaagcg acaatcgcaa aagctgcagc tggaatcgca
    12601 ttgatattga gaccagttcc ccattgctga ttgagggctt tcaaagccaa aggaattccg
    12661 tagtaggtca acatgagttg caccaaaatc ggtgtccctt ttaagaaact aacaaagaag
    12721 gcctgcaagg gatataaaat cttgacacga ttgatcttca caatggcaaa aagaagcgcc
    12781 aaaaccaagc caaaaagggc accaccaatt gtcaacataa ttgttgttgg aagttgttgg
    12841 acaattctag ggattccatc aaagaccgaa cgtaggctaa acagcttgcc atccggaatc
    12901 aattgcatca agttttggta ccaatctgat gctaaaatcg ttgtaacatt cataaaaaca
    12961 tcctcttctg ataatgattc attctaccat gcttctgccg tcaatgaaat tatttgctac
    13021 ggtcagatac agactttgtc tacctactag tttatcatac tttgaaacag ggaagttata
    13081 tattttatct atcaaagaga tagataaaaa ctatttcagt cccagttctt cataagattt
    13141 tcgataaccg atttgcttaa cagttccatt ttctactaaa atgggccgtt ttaacaacat
    13201 accgtcactt gctagcaact cagccgcttc ttggtttgac aaacttccta ccttatcttt
    13261 tagccctaat tcacggtatt tgataccact ggtgttgaaa aattgcttca attcaaatcc
    13321 tgaggtttct agccaattca aaatgacttc ttggctaggt gtttcttcca cgatatggac
    13381 ggctttatag tccacaccta attgatttaa ttcttgtttt gcttttttac aagttgaaca
    13441 tttggggtat tcgataaatt ctaacatgtg cttctccttc tatttgttta tatctttaaa
    13501 atctacgcct tcatgctcca agagccaagc tttcttttcc actcctgcag catagcctgt
    13561 cagacgcttg cctgctccca acacacgatg acaaggtact aggatagacc aaggattgcg
    13621 tcccactgct ccaccaattg cttgagcaga agccacttgc aggtcttgag caatttgtcc
    13681 ataggtcact gtctgaccat aaggaatgcc ctgtaaatag tcccaaactc tcttttcaaa
    13741 attcgttccg attggcgcca agagcaagtt ggataaatcc tgaggcttgc ctttaaagta
    13801 atcatctaag caagcaataa ctgggtctaa aataggatga ctaacaactt cttctatcgt
    13861 ttcatctcct agtcccctct caaaatgctt ctgctcctga acccaaattc catacaaata
    13921 atggtcatca gctacaagtg atagaatacc aattggtgag gagtagagga tttttacata
    13981 cttcttttgc attatttctt taatttttga taggccaagc gttcgccatc tactggcacc
    14041 ttaccaactt gtttaaaacc aagtttttca aaaatatgtt gcataacctt gttttcagca
    14101 tgcgtatctg agcgaaaatc aagataatca aaaccttcaa tcaagccctc taagaaggtt
    14161 tgagcaactc cttttccctg cacatctgct gccacagcaa tacggtgaaa gactagatac
    14221 tctgactctc cagcttgcca gtttccctca taaatagctt cataggcctc ctctggactc
    14281 ttggtcacag cagcataggc tagcagttct ccctcttcca aggctacgta ggcttgccct
    14341 gagatgatat catcgataat aacatctgca tttggatagc cattttgcca ctggttacta
    14401 ccagcatctg ctaaacattt tttggcatcc tctatcacct gcatgatggc atctacttca
    14461 tttggaaaag ctaaacgaat ttccatcttt tttcctcatt tctgactagt ttctcccatc
    14521 atagcataat ttaagtcttt ctacaagcag ttaaaacttg actttgtatt tttgttattt
    14581 tataatctag ttatcaaaac tatataaaaa ggagttgaaa atgaaaacta ccttttccta
    14641 cccaaaatgg gcagaaattc caaacattaa cctctatctg gaccaggttt tgctctatgt
    14701 caatcaggtc tgcgccccta tctctcctaa taaagacaaa ggcctaacag catctatggt
    14761 caacaattat gtgaaaaatg gttacctgac aaagcctgac aaaaaaaaat accaacgcca
    14821 acagattgcc cgtttgattg ctatcacaac cctcaagtct gtattttcta ttcaagaaat
    14881 agcccagaca cttaatactc tacaaactca agcaagttca gaccaactct acgatgcttt
    14941 tgtggactac atgaaccaag gaattgaccc agctaaccct attatccaaa ccagctgcca
    15001 aaccgttaaa ctctatcatc aaactctaga cttaatcgat catactcaag aggaggtaat
    15061 ccaatgaaca ctagtcttaa actcagcaaa caactcagtt ttggagagga gattgctaat
    15121 agcgtgaccc atgctgtggg tgcagtcatc atgcttatct tgctgcctat ttcatccatc
    15181 tatagttatg aagcacacgg atttttatcc tctatcggcg tttccatttt cgtcatcagt
    15241 ctctttctca tgttcctatc atccaccatt tatcactcta tggcctatgg ttcgacccac
    15301 aaatatgttt tgcgaatcat tgaccattct atgatttacg ttgccattgc cggctcatac
    15361 acgcccgttg tcttgacctt gatgaataac tggtttggct atctgattat tgtcatccaa
    15421 tggggaacga ccatctttgg tattctctat aaaatctttg ctaaaaaggt caatgagaaa
    15481 tttagccttg ctctttacct gattatgggc tggttggttc tggctatcat tcctgccatt
    15541 atcagtcaaa cgacacccgt tttctggagt ctcatggtaa ctggcgggct ctgttataca
    15601 gttggagctg gattttatgc caagaaaaaa ccttatttcc acatgatttg gcatctcttt
    15661 atcctagctg cgtccgcact tcaatacatc gctattgttt attacatgta aaaaagttga
    15721 gaaattcaat ctcaactttt ttctttacac atattgataa agtactggtg caagcgcaca
    15781 tcatcagtca attctggatg aaaagaactt accaacatat ttttttcttg ggctgcaaca
    15841 atttgattgt tcactgttgc taaaatttct acaccctcac caacactact gataatcgga
    15901 ccacggataa aggtcattgg aatcttgcca actcccttac attctgcttc cgtgtagaaa
    15961 cttcctaatt ggcgcccata agcattacgc tcgaccacca tatccatagt tcctagatga
    16021 ctctctttct gagaagtgat ttccttagcc agcaaaatta agcccgcaca ggtcccaaac
    16081 actggtaagc cagatagaat ggcttctcgg atgggaagta gcatgttctg gtcacgtaag
    16141 agcttgccca tggttgtaga ctcaccacca ggcaaaatca aacccgacaa gtcactctga
    16201 tcttgctgaa aatcatctag atttctgagt tctacactct cgacacctaa ttgatctagc
    16261 acttttgcat gttctgcaaa ggccccttgc aaggccaata ttccgatttt catctatttt
    16321 cctcgttcag ccatgagaat ttggatttca ttttcattaa taccaaccat ggcttctcct
    16381 aaatcttcag agatttgagc taggatttga ggattacgga agttagtcac agccttaaca
    16441 atggcactcg ctcgtttaac aggatctcct gacttgaaaa tacctgaacc gacaaagacc
    16501 ccctctgccc ctaattgcat cattaacgca gcatctgctg gcgttgcaac acctccagca
    16561 gcgaaattta caactggcaa ttttccatgt tcatgaacat attggaccaa ttctacaggg
    16621 acttgcaaat ccttggcagc aacataaagc tcgtcctcac gtaagttttg aatgcggcga
    16681 atttcctgat tcatcatacg catatgacga acagcttgga ctatatcccc tgtccctggt
    16741 tctcctttgg tacgaatcat ggaagcacct tcagcgatac gacgcaaggc ttcacccaaa
    16801 tccttagcac cacagacaaa aggaacttgg aattctttct tgtccacatg gaaacggtca
    16861 tcagctggag atagaacttc actctcgtcg atataatcaa tttcaatagc ctctaaaatc
    16921 tgagcttcaa caaaatgccc gattctgacc ttagccatta ctggaatact aaccgcttct
    16981 tggatttcct taatcatctt tgggtcgctc atgcgggaaa ctcctccagc tgcacgaata
    17041 tcagccggaa ttcgttccaa ggccatcaca gctgccgcac cagcagcttc tgcgatacga
    17101 gcctgttcag gattctgcac atccataata acaccaccct tgagcatctg tgccaagttt
    17161 ttatttagtt cataacgatt ttcagtcatt tgttttatcc tcatcatttg tattggtagc
    17221 taccttttca ttttaagtca gaacagaatg aagcacaaga taaaaaaact ataattgtat
    17281 ggggacagat tagctaaaaa ctatctgacc ttaacttaag gccagatagc tcattcattt
    17341 ttatttttca gccgtaaggg cagccattgt gatgtagttg tatggtttgt tgaagtgtgg
    17401 caagaagaag aggtctgtca atgccaattt atcaattgtc acatgctctt ggatagcaag
    17461 tgagaacatg tggattccca tgctaattgc aatatcatgt gaaaccattt gggcaccaag
    17521 aatttcacgg ctatctttgt caaagacaat cttaattgct acttcatggt tgtcatgttt
    17581 catgaattct ggtttttgaa gatcgttaaa gcctgtttca gttgcgttgt aaccagcagc
    17641 tttcgctttt tcaagagtca aaccagttga aaccatgtga agaccgtaga ttgagatacc
    17701 atttgaacct tgaacaccga ttccttccaa ttcatgtcca caagcattgt aggcaccaac
    17761 gataccagtg cgaacagcat ttgaagcaag agcgatatag cttgtatctt tacgagcatt
    17821 gtcataaaca gtcgcacagt caccaacagc gtaaacgcct gggatagatg tttcttgttt
    17881 cttgtctaca aggaaggcac cgttgcggaa gagttcgatc ttaccatctg caagggctgt
    17941 gtttggacgg aaaccaactg caaggataac catatccacg tcaaagcttt ctttgtcagt
    18001 aatcaagcgt tcaactttac cgtcaccttc gattgcttta acagtttgac ctagagccaa
    18061 gcggatgttg tgatcttcca agttcttcgc catcatttgt gtgaagtctt tgtcatagta
    18121 accgttcaag acagtatcaa cgatatcaac aaggacaact tcttttccaa gacgttcaaa
    18181 ggcttcagca agttcaacac cgatgtaacc accaccaaca acggcgatac ggtcgaggtg
    18241 ttggctcttg tcagaaagtt tattgataac ttcttcagca ttttggtaca atttcacgaa
    18301 ttgtacgttt tcaagagttg ctttaaattc gcggtttcct ttaacaattt caacaccttc
    18361 gattggtggc aagattggtg tagaacctgt agcgaaaatc aatttttcgt atgattcttt
    18421 gtgctctttt ccttcaactt ccgctgtaac tactttgtta tcatagtcga ttgaaagaac
    18481 aggtgagttc atgtaaactt tagcaccttt agcttccaat ttttctttat cagaatagaa
    18541 caagccttca gcaccgtcaa tttgttcacc aatccaaaga gccattccac atcctaggaa
    18601 agagatgtta gagttttggt caaatacaac aatttcgttc tcatttccaa aattatccaa
    18661 catggtattg atacatgctg taccagcgtg gttagcaccg actacaacga ttttactcat
    18721 aaaaatttcc tgccttcatt ctaaatttac cttactagta taccatttac cgttagcgtt
    18781 tacaaggggg gtactattat ttcagcattt tttatcaaaa ataattcccc atttatcctg
    18841 ttttcaagcc tcatgaattt tatgagcata tttcttgact ttttccaaat tttgtttgtg
    18901 aaaattctaa ctttatggta ttataataac atgaaaatga aatgtaaggg cttcaattta
    18961 gatgattatt tgatattaca acttattttc tataagagaa aggagttggt agcttgactc
    19021 ttcgttcaca ttctgaacgg ctaatgggga ctactatcac tatttcatta gtggatgagc
    19081 aagccgatat ctttctccaa aaatcctttg acttgctcaa agaacttgaa taccgcttca
    19141 acgccaatag tcaagaatct gagttgatgg aaatcaatta tcaagcagga atagcccccg
    19201 tcacggttca tccagacctg tttgagctga tttcacttgg gttagagcat agcctagcgc
    19261 tctctagcca cctcaatatc agcattggtc ccttaattca aacctggcgt atcggttttt
    19321 cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt gctgcctcta atcaatcctc
    19381 atggtatcga gttagattct tctacttcta ctgtgttttt aaaacagaaa ggaatgaaga
    19441 tcgatctagg ttgtttagcc aaaggataca gtgcggataa ggttgcccaa tttcttagga
    19501 aagagggggt gacttctgcc ttgatcaatc tgggagggaa tatcctgacc attggaaaaa
    19561 atcaggcaag aggggataac ccatggcaaa tcgggattca agacccagcc aatcctaggg
    19621 gaaatcattt aatgaccatc cctgttgtca ataaatctgt cgtgacttca ggcatttatg
    19681 aacgtcacct gaccgtcgat ggacaagatt accatcacat ttttgacagt caaacaggat
    19741 atcctgttga aacggaacta gcgagtctaa caatcatctc tgataaatca gtcgatggcg
    19801 aaatctggac gactcgactc tttggagaaa gacctgcttc tatcctctgg caagtcgaaa
    19861 gtttggaggg catcgaagtc atcctcatcg ataaagaagg ccacctaagc tgttcttcag
    19921 gaattcctac tctatagaga caactgtttc aatggaattt taaaattgta ttatgtaaaa
    19981 agagaaagga aatctcatgt taaaacttat tgctattgtt ggaacaaatt caaaacgttc
    20041 tacaaaccgt caattgcttc aatacatgca aaaacacttt tctgacaaag ctgaaattga
    20101 gcttgttgaa atcaaggcca ttcctgtctt caacaaacca gctgacaagc aagtacctgc
    20161 tgaaatattg gaaattgctg ctaaaatcga agaggcagat ggcgttatta tcggtactcc
    20221 tgagtatgat cactctattc cagctgtttt gatgagcgct cttgcttggt tgtcttatgg
    20281 tatttaccca cttttgaaca aaccaatcat gattacaggt gcttcttacg gtacgcttgg
    20341 ttcatctcgt gcccaattgc aacttcgtca aatcttgaat gctcctgaaa tcaaggcaaa
    20401 tgttcttcca gatgaattct tgctctcaca ctctcttcaa gcatttaacc caagtggcga
    20461 cttggttgac cttgatgtta tcaagaaatt ggatgccatc tttgatgact tccgtatctt
    20521 tgtaaaaatc acagaaaaat tacgtaatgc acaagaatta cttcgcaaag atgctgaaga
    20581 ctttgactgg gaaaatttgt aagataggag accaaaaaga atgaaatttg ttggacttgt
    20641 tggatcaaac tacgatcaat catataaccg taagctcttg gaatttatcc gtcgctactt
    20701 caaactcaaa tttgaattag aagttcttga aattgacgaa gttccaatgt ttaaccaaga
    20761 tgaaaaatgg gatgaaagtt tccaattacg ttatttatat aacaaaatta ctcgtgcaga
    20821 tggtgttatc attgctactc ctgagcataa ccacactatc tcagcttcac tcaaatctgt
    20881 acttgaatgg ctttcatacg aagttcatcc atttgaaaac aagcctgtta tgattgtggg
    20941 tgcatcatac tatgaccaag gaacatcacg tgctcaagtt caccttcgta aaatccttga
    21001 tgctccaggt gttaatgcct acacgcttcc aggtaacgaa ttccttcttg gtaaagctaa
    21061 ggaagctttt gataacaacg gaaatatcac caacgaaggc actgttaaat tccttgaaac
    21121 ttgcttagat aactttgtta aatacgtagg agtcgtttcg aaattgaaaa aaccaaaacc
    21181 aatcgaatca gaagacttgg attgtggaaa accaatcgct acaaccatca cagaagttga
    21241 ccctgacgat ccagaatggg tagaaaaagt tgcagcaatc actggtgctg tttctggtga
    21301 tacctatgtc aaattggacc acggtatcct aacagttaac caaattgata tgttcttgaa
    21361 agctatgcca tttgaattga catacgctga cgacaacaac caattcctct actacaacaa
    21421 cgctcaccaa gatccagaca ctatgttcgc taaacgtgta ccacctcaat caggtagccg
    21481 tatgtcgact gttcatggtt ctcttccacc agcacgtatg aagaacgtag agtgggttat
    21541 cggaacactt cgcaacggaa accaagaata cgtccgtacg atcgttccag gttctcctgc
    21601 aggtgttatc aacactcaca actaccaagc aatgtactat cctgatggat catacgctgg
    21661 tatcaatgaa atcgtcttta acttccaacc atggcttgac tggtacctaa aagagactgg
    21721 tcaacgtttg gtgggtggta gcggaccatt tgctcctgct gccggaggtc atggagacgc
    21781 cgatgctact tctggcgctt ctgattcagg ggatgctgga ggccacggtg gtgacgcaga
    21841 cgctacagcc ggtgcaagtt actaatgata gtttttagga accattatgg ttcctttttt
    21901 agcgaaaaaa gactagcaaa cacaaactgc tagtctcttt gttatcgttt catctatctt
    21961 tgttaaaaga aagagtactt atactcaatg aaaatcaaag agcaaactag gaagctagcc
    22021 gcaggctgta cttaagtacg gcaaggtgaa gctgacgtgg tttgaatttg attttcgaag
    22081 agtattatta tgaatttggg tcatcaagac tacggccatg taatcctttt tcacgttgta
    22141 cttggcgtag tttttctggt gtaacatcgt ttccttcttc gtccacaatt ttgattcctt
    22201 caatgtggtg acgaacagcg cggcgataac cttcgatgta ctcctcacgt agtttggctt
    22261 gttccacttt ttcttctgat gttaagcctt ctgttttttt ctttttagca agctcattga
    22321 tacgagcaat ttttttcgga tccatttctt ctcctttgta ataagataaa gtccgtttat
    22381 caaattttat ttagtgttaa tttggttaaa acaagcaaac ttagctgctt tcttggttag
    22441 ttgtgacaag attgccaaac gattttgacg gacagcctga tcttcagcca ttaccatagt
    22501 attttcaaag aaagcatcaa tgactgggct aagcgcaaag agttgtttca attgctgact
    22561 tgcaggtcct gataaaacga gtgtttctac tgcttctgcc aaagcttttt cttggtcatt
    22621 ctcaaatagt gctgaatcaa ctgtagcaac cccttctgcc ttctcagcca ggttaaaggc
    22681 acgagaaagt gattcaacag atggtttaaa atattcttcc ttgcttactt ctacgagagc
    22741 acttgctgct tccaacatat ctgccacaac aaagtttgaa cctgcaagaa ctgcttcctt
    22801 gatatctttt ggagtagagc ccatcatctt atcaacacga gccttgataa agtccataac
    22861 ctctgcttta ttttcataag tcaaactgtc aaatttcaat gcataaaggc tatcaatcag
    22921 ctcatccata gcaatgtgcc aaccaaaggc atccaagata cgaaccacac cttgagttgc
    22981 acgacgaagg gcataagggt cattagaacc tgatggaatc aatcctactg agaagaaact
    23041 caaaatcgta tccaatttgt ctgcaatggc tagaactgcg ccgaccttgc tctctggaag
    23101 ttctccttca gctgatgtag gcatgtagtg ttcacgaata gcagctgcca ccgctggagt
    23161 ttcaccagca agaagggtgt atttttcacc cataattcct tggagttcgt caaattcacc
    23221 aaccatacct gtcaataagt caaacttgta aatggctgct gcacgagcaa ggtcaactgt
    23281 ttcatccact gacaaaccag ctttttctgc caaaagtaca gtgatttgac ccgtacgaat
    23341 catgtgttca cgaagggaac caatcttctc atggaaggtg acattgttta atttttcaac
    23401 aagatctgaa atcaccaatt tttggtcttc acgccagaag aattctccgt cttccaagcg
    23461 ggctaccaag actttttcat ttcctttaat gacatttttc aaacgctctg cgtttccgtt
    23521 acgaacagaa atgaagtttg gcaagagttt tccatcttga tcacgaacaa caaagtaacg
    23581 ctggtgttcc ttcatagaag tcaccaagac ttcttctgga acttcaaggt atttagcatc
    23641 aaaacttccc atgaaggcag ttgggtattc aaccaaattc aagacttcat tcagcaaatc
    23701 cgcatcaatt tcgatacgta caccatgttt tgcctcaatt tccttgattt ggtcaacaat
    23761 catttgctca cgttcacatg gatctgcgat tacaaactgc ttacgaaggt cttcttcata
    23821 gctcaatgct gactgaattt tggtttcttt ccccaagaaa cgatggccac ggctcacacg
    23881 acttcccttg atatcaagga aatccaagtc aaactcttgc tcatccaaga gaacagttaa
    23941 agtgtggaca ggacgaatgt attcaaagct atttccagcc cagtgcatgc tgacagggaa
    24001 agtcaatgac ttcaagacat ctacaacacc aggaacaatg gcttcaactg cttgaccaac
    24061 ttcttcctta gtgacataga catattcttc acccttgatt tcacggaatt cgatatcttc
    24121 aacagtcaag ccttttccac ggacaaatcc ttgagctgct ttggtaaagt ttccatcact
    24181 atccaaggca attttctttg ctggtccctt gaaatcttct gtcaaatcag actgtttgtc
    24241 tgataaacca gtcacacgaa cagccaaacg acgtggtgtt gagaaggttt gaatggcttc
    24301 aaaagacagg cggttttcct tgaggaaggc tgccattttt tcgcctagtt gtttttcact
    24361 tggtgtgaca acataggctg gtaattcttc aagaccgagt tctactaata agttttttgt
    24421 catgtttttt cctttacatt ttcttcaatc ttttttgata tgcaccttag gtactgggga
    24481 cgtcgctaac taactctgtg agtctgtatg gaaatccaat gctaaattta tcaagatttc
    24541 caacaatctc atcaaagtgg atttagctga ctgatttttg aacctaaggt ttcaaaaatc
    24601 cccacataac agtacggcgg tgcatatacc tctagcaagt cttcgacttg cctctaacga
    24661 ttttagagta cagtattact cactattctg cgtcttctgc taaaagttta actcgtgttt
    24721 cttcatccaa aagtgggtaa cctaggcgtt tgcgttctgc aacaaaggtt ttggctacaa
    24781 cacgggccaa gttacggata cgagcgatat agcctgcacg ctctgttaca gatacggcac
    24841 cacgcgcgtc aagcagatta aaggtatgtg aacatttgag aacatagtca taggcagggt
    24901 gtaccaagcc ttcttctaat gcacgaccag cttctttttc aaacttatca aagttttcaa
    24961 gcaaaatttc ttggtccgaa atttcaaatg aatattttga gtgctcatac tcaggctgga
    25021 taaagatttc tccgtatttt acaccatcag cccactcgat atcatagaca gagtctactt
    25081 cttgaatgta agaagccaag cgctccaaac cataggtaac ttccgcagtc acagggccag
    25141 ttgccaatcc accgacttgt tggaaataag tgaactgagt gatttccatt ccgtcaagcc
    25201 aaacttccca accaagacca gctgaaccag ttgatgggtt ttcccagttg tcctcaacaa
    25261 aacgaatatc gtgctccaaa ggattgattc ccaatttttc caaagactca aggtaaagtt
    25321 cttggatatt tgatggagaa ggcttcatga ccacctggaa ttggtggtgt tggtagagac
    25381 ggttagggtt ttccccataa cgaccgtcag caggacgacg tgatggctct acataagctg
    25441 cattccatgg ctcaggtccg atagcacgaa ggaaagtgta aggactcatt gtccccgcac
    25501 ctttttcatt gtcataagcc tgcataagca tacaaccttg gtcattccaa aattgttgca
    25561 aagtcaaaat aatttcttga aatgttaatt tcttagacat tgtttactcc ttaataaaaa
    25621 atgatttctt gcgacacgag tct
//
LOCUS       DAVBOM010000030        25526 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBOM010000030 DAVBOM010000000
VERSION     DAVBOM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.030"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            176..2855
                     /locus_tag="VQ878_001306"
                     /pseudo
     CDS             176..2855
                     /locus_tag="VQ878_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            3156..3995
                     /locus_tag="VQ878_001307"
     CDS             3156..3995
                     /locus_tag="VQ878_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3095646.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            4013..5851
                     /locus_tag="VQ878_001308"
     CDS             4013..5851
                     /locus_tag="VQ878_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3095647.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            5864..7279
                     /locus_tag="VQ878_001309"
     CDS             5864..7279
                     /locus_tag="VQ878_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3095648.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            7871..8917
                     /gene="pheS"
                     /locus_tag="VQ878_001310"
     CDS             7871..8917
                     /gene="pheS"
                     /locus_tag="VQ878_001310"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET3095649.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            8917..9426
                     /locus_tag="VQ878_001311"
     CDS             8917..9426
                     /locus_tag="VQ878_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095650.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            9503..11905
                     /locus_tag="VQ878_001312"
     CDS             9503..11905
                     /locus_tag="VQ878_001312"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET3095651.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(11973..12974)
                     /locus_tag="VQ878_001313"
     CDS             complement(11973..12974)
                     /locus_tag="VQ878_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3095652.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            13130..13577
                     /locus_tag="VQ878_001314"
                     /pseudo
     CDS             13130..13577
                     /locus_tag="VQ878_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            13703..13969
                     /locus_tag="VQ878_001315"
     CDS             13703..13969
                     /locus_tag="VQ878_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095653.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            14229..16478
                     /gene="metE"
                     /locus_tag="VQ878_001316"
     CDS             14229..16478
                     /gene="metE"
                     /locus_tag="VQ878_001316"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET3095654.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYFFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            16542..17408
                     /gene="metF"
                     /locus_tag="VQ878_001317"
     CDS             16542..17408
                     /gene="metF"
                     /locus_tag="VQ878_001317"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET3095655.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            17967..20180
                     /gene="pnp"
                     /locus_tag="VQ878_001318"
     CDS             17967..20180
                     /gene="pnp"
                     /locus_tag="VQ878_001318"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET3095656.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            20196..20813
                     /gene="cysE"
                     /locus_tag="VQ878_001319"
     CDS             20196..20813
                     /gene="cysE"
                     /locus_tag="VQ878_001319"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET3095657.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            20825..21709
                     /locus_tag="VQ878_001320"
     CDS             20825..21709
                     /locus_tag="VQ878_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095658.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            21791..23134
                     /locus_tag="VQ878_001321"
     CDS             21791..23134
                     /locus_tag="VQ878_001321"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET3095659.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            23127..23513
                     /locus_tag="VQ878_001322"
     CDS             23127..23513
                     /locus_tag="VQ878_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET3095660.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            23517..24401
                     /locus_tag="VQ878_001323"
     CDS             23517..24401
                     /locus_tag="VQ878_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET3095661.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTYVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            24538..24972
                     /locus_tag="VQ878_001324"
                     /pseudo
     CDS             24538..24972
                     /locus_tag="VQ878_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25280..25450
                     /locus_tag="VQ878_001325"
                     /pseudo
     CDS             25280..25450
                     /locus_tag="VQ878_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         7875 a         4483 c         5664 g         7504 t
ORIGIN      
        1 atgcgttttt tgaattttat agactgctcg tttaaactct atttacttcg tacattccgg
       61 agcgagatgg actattagtc gcatacaaaa tgagtgctat tcggatttta ttttcgtgta
      121 caatttcagc cattcttgtt ataatcagcc tataggaatc aaggaggtga ttgttatggc
      181 tatttttgtg tctttggatg gaattgtggt agaagtactt gatgtctttt cttcttttaa
      241 tggggatagt gagtttttct tgtgtaaacg tcttaaagac aagagtcagt ttgtgatgga
      301 acgctctcgg ttcgaggaga tgttccaact tcaaagtagt cacttgacga cgcaagaaaa
      361 attacaattg tttacctccg tgtttgctgg ccgttatgat gtttatgcta agagttttat
      421 caatgatcaa gggaaaattc agtattttcc ttcctatgat tatggttgga agcagttgcc
      481 acttgaaaaa cggagtttcc agacattgac ggactccgtt ttgaaatctc attttcgtgg
      541 ggagacagct atcggtatct ttcctatgca cttagatgat agctgtcatt ttttggtact
      601 ggattttgat gaaggagatt ggaaagaagc tggtttaacc attcgaagaa tagccaggga
      661 acgccagatg gaagcccatt tagagatttc tcgttcgggt cacggactcc atatttggtt
      721 cttctttgag gaagcgattc cgagtcgaga ggctcgcttg tttggaaaga aactgataga
      781 actggcaatg caggaaagta tgcaactgtc ctttgattct tttgatcgca tgtttccaaa
      841 tcaggatgtc cttcctaagg gggggatttg gaaatttgat tgccttgcct tttcaaggag
      901 aagcttacca tcaagggcga acggtctttg tggatgaaca gtttcagcct tatgaagacc
      961 aatggaggta tctacaagaa attcagaggg tttcaactgc taaagtggca ctgttaatcc
     1021 aagaagagtt aggcaagcaa gaattggaca aggagttgaa gatcgtctta tccaatatga
     1081 tccaacttga aaaatcgtct gtgacaccca agacactgtt tttcttgaaa aatatggctt
     1141 cattttctaa tcccgaattt tatttaaagc aggctatgcg acagccaacc tatcaaattc
     1201 ctgagagaat gtatttattt ggagaatccg attattattt atggctgcca agaggcttgt
     1261 tatatccatt gcaagataaa tttaagcagg tatctgtgga agataggaga aaggtacaaa
     1321 ggtctattag cgtggaattt aagggagaac tcacttttga gcaagagtta gccctgtcag
     1381 atatgacttc taaagaaaat ggtttacttc atgcggagac tggttttggg aagaccgttt
     1441 taggtgctgc tcttatctct gaacggaaaa caaaaacaat tattctagtc cataataagc
     1501 aactcttaga ccaatggcta gatcgcttaa actgcttttt gactttcgaa gaggaggagg
     1561 ctatccgtta tacggcatca ggtcgtgaaa aggtaatcgg ctatgttgga cagtacggtg
     1621 ggactaagaa atggctgagt aaactggttg atgtcgttat gattcaatct ctatttaagt
     1681 tggaaaatag tcaaagtctt ttggatgagt atgagatgat gattgtggat gagtgtcatc
     1741 atgtctctgc cttgatgttt gaaaaagttg ttgctcagtt tagagggaag tatctttacg
     1801 gtttgacggc tacgcctgag cgtaagaatg gtcatgagcc tattgttttt cagagaattg
     1861 gtgagatact ccatactgct gataagaggg aaacggattt taaacggcaa ttgcaattaa
     1921 gattcacttc ttttggtcat ttggagattg aaaagaccaa agcaagtaat tttatacagc
     1981 tcagtgattg gattgctaca gactcagcga ggaatcagtt gattctcaag gatattctag
     2041 cccaagtggc agaaggacgg aatatcttgg ttttagttaa tcgaattcaa cagatagatg
     2101 tctttgaaaa gttattgaaa gagaaagagg ttgatgactg ttacattatt agcggaaaaa
     2161 ccaaagtccg agaaagaacg agtttactgg agacgttaga acagttagat aaagggtttg
     2221 ttttgttgtc tactggaaaa tacattggcg aaggttttga cttacctcag ttggacacgc
     2281 ttatcttggc agcacccttt tcttggaaaa ataatttaat tcagtatgca ggtcggattc
     2341 atagaaacta caaggataag tctttggtgc gtattttcga ttatgtggat attcatgttc
     2401 cttatttaga aaagatgttt cagaaacgac aagtagctta tcgaaagatg gattatcgtg
     2461 tcatcgaggg tgaggagaaa caattcgttt atgttgatag tagatatgag aaggtgttga
     2521 gagaggactt agcaggggaa agacaggaat gtctgcttat tttaccttat gtgcaccaga
     2581 caaaactgat gaattttcta aaagaattta ggattagtca aattgagata tgtataccag
     2641 agacggttgc aaataaagca tggctagacc agttgaagag ccagaaaatt aaagtgtctt
     2701 ttactcaatc aaaaatagta acgcctattc ttttggtgaa taagactatt gtttggtatg
     2761 gtgcaatgcc attattaggg aaggtagatg agatgaccat attacgtttg gaatcagcta
     2821 gtatagtttc tgaactagtg gcaggtttac gatagagaaa atttttaaaa atttctatgt
     2881 atgattttca tttctttagt gagactgttg ccattatcac attcgaatca cacaaaataa
     2941 aaaaattttt ataagtactt gacaaataga ttgaaatatc ataaaataaa aacggttaca
     3001 gagttattaa ttatttaagc ttcatgtcac cattaaaaat tgaaataaaa ggatgttatc
     3061 actaatacaa gtgagcagga acctatttaa tcacatcaga agaagtttct tgatgttttt
     3121 taagtaggtt ccttttattt taaaagggaa attttatgat cataaaacga atactaaacc
     3181 acaatgccgt aattgcgcaa agtaaaaaag atatcgatat tcttcttttt ggaaggggaa
     3241 tagcttttgg aagaaaaact ggagataaag taaatccaat tgatattgag aaaagttttt
     3301 ttctcaaaaa tagagataat atgacccgtt ttacagagat gtttattaac gttcctttgg
     3361 agttggtgta catcaccgaa aaaataatta acctaggtaa aataacatta ggtaataatt
     3421 ttgatgagat tatctatata aatctaacgg atcatatttc ttcgagtata gaacgttata
     3481 aagaaggagt tattatttcg aatcccctac gctgggaaat ctcgaaatat tataaagaag
     3541 aatttgagct tgggaaaagg gctttacaaa taataaaaaa agagttaggt attgaacttc
     3601 caattgacga agctgcattc atagcgctac attttgttaa tgctaattta gaaaataatt
     3661 ttcaagagtc gtataaaatc actgaaataa ttatgggaat tgagaaaatc attcaagatt
     3721 tctattgtac tgagtttaac caagattcta ttgattatta tagattcata actcatataa
     3781 aattatttgc ccatcgcttg gttgaaaata caacttattg tgacgatgat gatgaagact
     3841 tgttagcatt aatgaaaaat aaatatccta gagaatatga atgtggtgaa caggtggcaa
     3901 tgtttataca aactgagtac aattatttgc tgacttctag tgaattagtt tatttgatgg
     3961 ctcatattcg tcgcttaaca aaaaatttag attaatagaa taggagaata ccatgagtta
     4021 taaagataag gtacaaaaaa tcctcgatgt aattggaggt gaaaaaaatg tcaatagagt
     4081 tacccattgt gtaacacgtt taagattaga attaaaagat gaaaatttag tcaatgatga
     4141 tgatgtgaag aagataccag gtgtaatagg tattatgaaa aagaatggac aatatcaaat
     4201 tatacttggt aatgatgtag ctaattatta taaagaattc gttaaacttg gcaattttga
     4261 atccgattca gttgttcaag ggcacaaagg gaatatttta gaaagaatca ttgagtatat
     4321 cgctggttcc atgactccaa tcattccagc aatgttaggg ggaggtatgc tgaaagtctt
     4381 ggtaattatt ttaccaatgc ttggtatatt gcaatcagat tctcagacta ttgctttttt
     4441 gacatttttt ggggatgctc catattattt cttaccgctg ttattagctt attctgcatc
     4501 acaaaaatta aaagtaacat ctacattagc tatgtctgta gcaggtgtac ttctccatcc
     4561 aaattttgtt caaatggtgc aatcagggaa tcctcttagt ttatttggtg tacctgtgat
     4621 accagctagt tatggttcgt cagtcgttcc aattcttatt atggtttggt tgatgaaata
     4681 tattgaaaaa atgattgcta aattaacacc agctgttact aagagttttt tgcaacctac
     4741 gctagtatta ttagtatcaa gctgtattgc cttagttgta gtcgggccta ttggagtaat
     4801 tgttggtgaa ggattatcaa atctagttgg gcaaatgtat gatgtagctg gatggcttac
     4861 attagctatt cttggtgcta ttatgccatt tattgttatg actggaatgc attgggcttt
     4921 tgcacctatt tttttggcgg catctattgc tactccagac gtattaattc ttccagcaat
     4981 gttagggtca aacttagctc aaggggctgc ttcgatggct gttgcattaa agagtaaaaa
     5041 taataataca aaacaaattg cttttgcagc aggtttctca gccttacttg cagggattac
     5101 cgaacctgca ttatatggtg tgactttaaa atataaaaaa ccgctttatg cagctatgat
     5161 tggtggtgga ttagcgggat tatttgcagg tcttactagt gttaaagcgt atctatttgc
     5221 tgtcccatct ttgatagcgt tgcctcaatt tatttattct gatgtaccat caaatattgt
     5281 aaatgcttta attgtggcgg ttatttcggt tgttattacc tttgtattag cttatatatt
     5341 tggaatcgat gaagaagaga gttctagcaa tttagaagtt aaagctggag tttcaaataa
     5401 aaaaatgata ttttctccta tatcaggaga aatcattccg ttaagcgatg tccaggataa
     5461 aacattttca gataaactaa ttggagacgg agtagcgatt attccaagtg aaggtaaggt
     5521 ttatgcacca tttgatggga aaattacaaa tatttttccg actaagcacg caattggatt
     5581 gaagagtgat gagggtgttg agttactaat tcatattgga ttagatactg ttgagctaaa
     5641 aggtcaaggt tttattagtc atgtagaaga aggagacaga gttttcaaaa atcagttgat
     5701 ttttgaaatg gacttgaatt taatcaagac taaaggctac gaaacagtta caccagtaat
     5761 tgtaacgaat accaatgatt ttctagatgt attagtatta cctaataatc agacaatcga
     5821 gcattctaag gaattactgg taatattata atggaggaaa gttatgacca tttttccaga
     5881 tgattttctt tggggtggag ctgttgcagc taatcaagta gagggagcat ataatgaaga
     5941 tggtaagggc ttatcagttc aggatgtgtt acccaaaggt ggattaggag aagcaacaga
     6001 aaatcctaca gaagataact taaaattgat aggtattgat ttttatcata aatataagga
     6061 agatatatcc ttgttttctg aaatgggctt taatgttttt cgtacttcta ttgcatggag
     6121 tagaattttt ccaaaaggag atgaggaaga acctaacgaa gctgggttga aatattatga
     6181 tgaattgttt gatgaactac atgctcacgg gatagaacca cttgtaactc tttcacacta
     6241 tgagactcca ttatatttag caagaaaata tcatggatgg attgatagga gaatgattca
     6301 tttttatgaa aaatttgctc gaacagtttt agaaaggtat aaagataaag ttaaatattg
     6361 gcttacattt aacgaagtaa actctgtttt ggaattaccg tttactagtg gaggaataga
     6421 tatacctaag gagaatcttt cgaaacaaga attatatcaa gctatacatc atgaattagt
     6481 cgcctcgagt ttggttacaa aaattgctcg tgagattaat tcagagttta aggtggggtg
     6541 tatggtatta gctatgccag cttatccaat gactccaaat ccaaaagatg tatgggcgac
     6601 tcatgagtat gagaatctaa attatctatt ttcagatgtg catgttagag gttattatcc
     6661 gaattatgca aaaagatatt ttaaggaaaa tgacattaac atagagtttg cagctgaaga
     6721 tgcagagtta ttaaaaaatt atactgtaga ttttttatcc tttagctatt acatgagtgt
     6781 gactcaatct gctcttccaa cacagtataa ttcaggagaa gggaatatta ttggtggttt
     6841 agtaaatcct tatttagagt cttctgagtg gggatggcaa attgatccaa ttggactacg
     6901 tataatttta aatagatatt atgaccgtta tcaaattcca ttatttatag tggaaaacgg
     6961 attaggtgct aaagatcaac taataaaaga tgaatttaat aacttaacag tccaagatga
     7021 ttatagaatt cagtatatga aagaacattt attgcaagta gctgaagctc tacaagatgg
     7081 tgtggaaatt atgggctata cgtcttgggg atgtattgac tgcgtttcta tgtccactgc
     7141 acagctttct aagaggtacg gtctcattta tgttgatcga aatgatgatg gaaatggcac
     7201 attcaatcga tataagaaaa tgtcctttac ttggtataaa ggagtgattg aatcaaatgg
     7261 agaatcctta ttcaaatagt ttgtttattg atgattagat attatcacgg ttaaggcagc
     7321 atctcattaa atatgaaata aagaggtttg gaagacatca aattctaaac ctctttattt
     7381 tataggggga ttaattaatt taattttgtt acagagagcc gattataaat agttaactta
     7441 ggatagattg gttatatata gtagactgaa tctaaaatag tacgaaacaa ttgctaaaac
     7501 atttatagaa attaatttta ctttcccaat cgatttgttt tcatcttatt tcaatccgct
     7561 ataaagttag ataagaataa gctaacaagc agaagtaaga taggtcttgc aagaatggta
     7621 aaaatctgat aaactaagtg gtaattgaat agaaatctga aagactagta gcccaaggga
     7681 agtatatcag ggaggagagc cgtgactgca agctctctat atgaaagctg ggtgaattca
     7741 cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga tgaaaacgga tggtaccgcg
     7801 tgtcaacgct ccgagtggag tttttggcat gtggttttct ttttatctac gagagactga
     7861 tggaggaaat atgtcaacta ttgaagaaca attaaaagcg cttcgcgaag aaacgctgac
     7921 tagcttgaag cagattactg ctggaaatga aaaagagatg caagatttgc gtgtctctgt
     7981 ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg atgaaagatg tttctgctga
     8041 gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt gatgtcttga cagctgcttt
     8101 tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg gctcaactgg ctagcgagag
     8161 tatcgatgtg acgcttccag gtcgtccagt tgcgactggt caccgtcacg ttttgacaca
     8221 aaccagtgaa gaaatcgaag atatcttcat cggtatgggt tatcaagtcg tggatggttt
     8281 tgaagtggag caagactact ataactttga acgtatgaac cttccaaaag accacccagc
     8341 tcgtgatatg caggatactt tctatatcac tgaagaaatc ttgctccgta cccacacgtc
     8401 tccagttcag gcgcgtgcta tggatgccca tgatttttct aaaggtcctt tgaagatgat
     8461 ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg acccacagtc accaattcca
     8521 ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg gctgatcttc aaggaacgct
     8581 tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa attcgtttgc gtccatctta
     8641 cttcccattc acagagccat ctgttgaggt ggatgtttct tgcttcaagt gtggtggaga
     8701 aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt atgggagccg gtatggttca
     8761 cccacgtgtc cttgaaatga gtggtatcga tgcgactgta tactctggtt ttgcctttgg
     8821 tcttggacaa gagcgtgtag ctatgctccg ttatggaatc aacgatatcc gtggattcta
     8881 ccaaggagat gtccgcttct cagaacagtt taaataatga ttagaaaagt agaaatggca
     8941 gatgttgagg tgttggctaa aattgccaaa caagcctttc gtgaaacctt tgcgtatgat
     9001 aatacggaag agcagttaca ggaatacttt gaagaggctt atagtctgaa aactttgtca
     9061 actgagttgg gaaatcctga ctctgaaacc tatttcatta tgcatgagga ggagatagct
     9121 ggttttctca aagtcaactg gggaagtgct caaactgaga gagaattaga ggacgctttt
     9181 gaaattcaac gcctctatgt gctacaaaaa ttccaaggat ttggactagg taagcaactg
     9241 tttgaattcg cacttgaact tgctacaaaa aatagttttt cttgggcttg gctaggtgtt
     9301 tgggagcata atacaaaagc tcaagcgttt tataatcgat atggttttga aaaatttagc
     9361 caacatcatt ttatggttgg tcaaaaagta gatacggatt ggttactgag aaagaaatta
     9421 aggtaagaag aggattcttc tattgaaatg ataggaaagg aaaagaacca gtgtggcaat
     9481 ggtcattctg gagaactaaa ttatgcttat atcttataaa tggttaaaag aattggtgga
     9541 cattgatgtg ccatcacaag agttggctga aaaaatgtca actacaggaa tcgaggtcga
     9601 aggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc gtcggtgagg tcttgtcttg
     9661 cgaagatgtg ccagagactc acctccatgt ttgtcaggtt aacgttggcg aagaagagcg
     9721 tcagatcgtt tgtggtgccc caaatgtgcg tgctgggatc aaggtcatgg tggctcttcc
     9781 aggagctcgt atcgctgata actacaaaat caaaaaagga aaaatccgtg gtttggagtc
     9841 acttggaatg atctgttcac ttggtgaatt gggaatttct gactcagttg tgcctaagga
     9901 attcgcagat ggcatccaaa tcttgcctga agatgccgtg ccaggtgagg aagtcttttc
     9961 ttacctagac ttggatgatg aaatcatcga actttccatc acaccaaacc gtgcagatgc
    10021 cctttctatg tgtggagtgg ctcacgaagt ggcagccatc tatgacaagg cagtcaactt
    10081 taaagaattt actctaacag aaactaatga agctgcggca gatgcccttt ctgtcagcat
    10141 tgagacagac aaggcgcctt actatgcagc tcgtatcttg gacaatgtga ccatcgcacc
    10201 aagtccacaa tggttgcaaa accttctcat gaacgaagga atccgtccca tcaataacgt
    10261 agtggacgtg accaactaca tcctgctcta ttttggtcaa ccaatgcatg cctttgactt
    10321 ggataacttt gaagggactg acatccgtgt gcgtgaagcg cgtgctggtg aaaaattggt
    10381 gaccttggac ggtgaagaac gtgacttgga cgtgaatgac ctagtcatca ctgtcgcaga
    10441 caagccagta gcccttgcag gtgtcatggg tggtcaagca acagaaatct ctgaaaaatc
    10501 tagtcgtgtt gtccttgaag ctgctgtttt caatggcaaa tctatccgta agacaagtgg
    10561 tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa aaaggaatta atgtggcaac
    10621 agttaatgaa gcccttgatg cggcagctag cctgattgcg gaacttgcag gtgcgacggt
    10681 gcgtaagggc atcgtttcag cgggtgagct tgatacttca gatgtagaag tttcttcaac
    10741 ccttgctgat gttaaccgtg tcctcggaac tgagctgtct tatgctgatg tagaagacgt
    10801 cttccgtcgt cttggctttg gtctttctgg aaatgcagac agctttacag tcagagtccc
    10861 acgtcgtcgt tgggatatca caatcgaagc tgacctcttt gaagaaattg ctcgtatcta
    10921 tggttatgac cgcttgccaa ctagtctacc aaaagacgat ggtacagcag gtgaattgac
    10981 agccacacaa aaactccgcc gtcaagttcg tactattgct gaaggagcag gtttgacaga
    11041 aatcatcacc tatactctaa caactcctga aaaagcagtt gagtttacgg ctcaaccaag
    11101 taaccttacg gaactcatgt ggccaatgac tgtggatcgt tcagtcctcc gtcaaaatat
    11161 gatttcaggt atccttgata ccgttgccta caacgtggct cgtaagaata aaaacttggc
    11221 cctttacgag attggaaaag tctttgaaca aacaggtaat ccaaaagaag aacttccaaa
    11281 tgaaatcaac agttttgcct ttgccttgac aggcttggtt gctgaaaaag atttccaaac
    11341 agcagcagtt ccagttgatt tcttctatgc taagggaatc cttgaagccc tatttactcg
    11401 tttgggactc caagtaacct atacagcaac atctgaaatc gctagccttc atccaggtcg
    11461 tacagccgtg atttcactcg gtgaccaagt tcttggtttc cttggccaag tgcatccagt
    11521 cactgccaag gcttacgata ttccagaaac gtatgtggct gagcttaacc tttcagctat
    11581 cgaagctgcg cttcagccag cgactccatt tgtagaaatc accaaattcc cggcagtcag
    11641 ccgtgacgtt gcccttctcc tcaaggcaga agtgactcat caagaagttg tagatgctat
    11701 ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc tttgacgtct tctcaggtga
    11761 gaaattggga cttggtatga agtcaatggc ttatagcttg accttccaaa atccagaaga
    11821 tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa atccaagcat cgctcgaaga
    11881 aaaagtcaat gcagaagtgc gttaaacgat agtatgatac aaattccccc tctagtttat
    11941 gaacactaga ggggtgattt tatataaaat aattaaaatg tgatttctgt aaaaatacat
    12001 ctatgatcag agttttgaaa acttacaatg tctaaatctt taacatagta gtggttttta
    12061 ggcaataaaa tatgatctat tgttgcatta aaaagttttg gactttggct attccaagtt
    12121 cctctttcaa aaggtggcag tacatttaat gcgtccctat gagagcttat ttttgcaagt
    12181 gctccatgac gcatagttgc attaaaatca cctgcaataa tagcctttgg atattttgaa
    12241 gccaattgat tatgaatgat gtttaagtct tgcttccaga tttccattaa acctggcaga
    12301 ggaggagcag tatgcaaggc aatgatatct ggtatatttt gttttctcga atgtaataca
    12361 attgtcccga accgtgttgt atgaaaagtt ttagcttctg tatagaaacc ataacttttc
    12421 ttgacaatca cagtcacagg agctattcca ctattggtag gtggagaagt gaaaatatca
    12481 tagttggcca tagaaagtcc aacttgatga aacaatagtt tgattctctg gttttcttgc
    12541 tcacctctga tattggtagc tagttcaggg aatatagcca tatcggcgtc aaaatggcta
    12601 aaaattcgct caatatgttg tgcttctatt tgattagcga cgttccaagt tactaatttt
    12661 aaggttttag tcttatttga tgcagaagaa agggttttat ctgttccgaa taatagtaat
    12721 atgagcgata gtaagagcaa aatgccagag taaaaccgta tttgtttatt tttcttgtaa
    12781 aaagatagga aaaaaaataa gaaacttaaa atagcagcca tagttgcagt agctaagggg
    12841 aaggcataaa tctgtgccaa gataggttgg gtagatagcc aaatgttaag attagaagat
    12901 gggaaaaaag aataagttat gatagggata acaaagagaa tgaccgaaag ggcagagaga
    12961 aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg ttgctcggag ctaatgtgac
    13021 tttgtgactt tacttgattg atattctttt tcttgtcttc ctcatagatt aagtacaacc
    13081 caagtaaaaa aagtccaatt taagattgaa atgattaaaa ggcacagaga tgcaagacaa
    13141 ttatactaca aaaggtaaac atttgacaat cgatagccgt cgcttaatcg aaagatggaa
    13201 aaaagaagga aaatcaaata gagaagttgc ctctctactt ggaaaagctc ctcaaactat
    13261 ccacactgaa atcaagcgtg ggacagtccg aaaatgtctt ggaaaagggc gcttcaaaga
    13321 ggtttattct gccgactacg ctcaacagtc ttatgaaaac aatcgcaagc gctcggtcaa
    13381 gaaatcaagc ttgaccaagg aactaaagga aaagattctc cactatacat aaccaaaaat
    13441 tttcgcctga aatgatggtt atggctaaag gggttaacgt gggaatttca accatttact
    13501 attggattca tcgtggaaaa ttggggttaa gcaagcagga tctgctttat cctagaaaag
    13561 gaaaatcgct taagaaatag gctagcacca actttaaacc cgctggtcaa tctatcgaat
    13621 cataattcgc tcattttttt aaaaatacat agacgtaaaa gaaagagggt taagtgatga
    13681 agaatagtgc tattgggagt aattggaagg atgtccatct gagctcttta gcaaggagga
    13741 aatccttgaa agtgatatgc gagtagctat catgagcgag ttgattgaag ccagaaataa
    13801 gcaaggaatc agtcagaaaa agctagagga actcagtgga gtgagtcagc ctgttatagc
    13861 taggatggag acaggtaaga ctagtccaca gttggacaca gtcttaaaag tcctagctag
    13921 tctaggaaag atactagcag tcgtccgact tgaacagggg aaaagttgac tagaatcagt
    13981 tatagtcttt tctaataaca agccatagtc acttataaga attactaata acgcgtttga
    14041 gcattctaac taaaatacag ctaaaaacaa gttataaaag ggatttgagg catgtgtctc
    14101 aagtcttttt cttttgtcta aaatagaggt atagtttcaa actatatcaa agcctaattt
    14161 tttacaatta tacagatgct ttcttttctg ttaagatagt ttcaacaaca aattttggag
    14221 gacacatcat gtcaactaca atcatcggtt tccctcgttt gggcgaattc cgtgaattaa
    14281 aatttacaac tgaaaaatac tttagaaaag aaatctcaga agaagaactt ttagcagcag
    14341 caaaagactt gcgtgctaaa cactggaaca ttgtcaaaga aaaaggcatc actgaaattc
    14401 catcaaatga cttttctcac tatgataact tcctagatgc ggctttcctt ttcaacgtgg
    14461 tgcctgcatc cgttcaaaac ttggacttgt ctgaccttga gcgctacttc gctttgggac
    14521 gtggttacca gggagaaaaa ggggacgttc gcgcccttcc aatgaagaaa tggttcaaca
    14581 ctaactacca ctacatcgtt cctaaatttg aaaaagacac tcaagtaaaa ttggctggtc
    14641 acaagatttt cgatgagttc caagaagcaa aagaacttgg attgaacact cgtcctgttc
    14701 ttgtaggtcc attcactttc cttcaattgt cagactttga agaaggcgtg aaagcagacg
    14761 acttcgtaga tagcttagtg gctgcttacc aagaagtttt tgctaaattg gctgaacttg
    14821 gtgcgactcg catccaattg gatgaagcgg ctcttgtaaa agacttgaca gctgaagaaa
    14881 aagctctctt cttgaacctt tacaacaaac tcttggctga caaaaaaggt cttgaagtct
    14941 tgcttcaaac ttatttcggt gatgttcgtg acgtatacgc tgaccttgta aacttgccag
    15001 tagatgctat cggtcttgac tttgttgaag gtaagaaaac tcttgaactc gttaaaggtg
    15061 gcttcccagc tgacaagact ctctatgtag gtattgtcaa tggtaaaaac atctggcgca
    15121 acaactacga aaagagcttg gctgttcttg agcaaatccc agctgaaaac atcgttttga
    15181 caagctcttg ctcacttctt catgtgccat ttacaactgc taatgaagaa tttgaaccag
    15241 cactcttgaa ccactttgcc tttgcagttg aaaaattgga tgaaatccgt gacttggatg
    15301 ctatccgcaa tggtcaaggt tcagaagctc ttgcagccaa caaagaactc tttgcgactg
    15361 agcgtgttgg tgaaaatgct gaacttcgtg cgcgtatcgc tggcttgaca gacgcagact
    15421 acactcgttt gccagccttt gcagaacgtg aagctatcca agaagaagct ttcaaacttc
    15481 cagctcttcc aacaacaacg attggttcat tccctcaaac aaaagaagtt cgtgccaaac
    15541 gtttggctta ccgtaaaggt gaattgtctc aaaaagagta cgatgctttc cttgctgaaa
    15601 cgattgacga atggatcaag tggcaagaag atattgactt tgatgtcctt gttcacggtg
    15661 aatttgagcg taatgacatg gttgagtact tcggtcaaaa cttgtcagga tacttcttct
    15721 ctaaaaatgg atgggtacaa tcatacggta tgcgtggggt aaaaccacca atcatctggg
    15781 gtgatgtcac tcgtcttaac cctatcactg ttaaatggtc tagctatgca caaagtcgta
    15841 caaacaaacc tgttaaaggt atgttgactg gacctgttac catccttaac tggtcattcc
    15901 cacgtgaaga catctctatc aaggattcta ctcttcaaat cgcccttgct atcaaggatg
    15961 aagtgcttga ccttgaagct gctggtgtga aaatcatcca aattgatgag gctgctcttc
    16021 gtgaaaaatt gccactccgt cgtagtgact ggtacgaaga ttaccttgac tgggcaattc
    16081 ctgccttccg cttggtacac tcaacagtag cgtcagacac acaaatccac actcacatgt
    16141 gttactcaga atttacagat atcatcccag ctatcgataa catggatgca gacgttattt
    16201 cctttgaagc cagccgttca aaccttgaaa tcttggacga actcaaagcg aaaaacttcc
    16261 aaacagaagt gggacctggg gtttacgata tccactcacc tcgtgtacca aacgaaggcg
    16321 aaatcgacaa cacaatcgaa gccatccttg ctaaagtgcc aagcaagaaa gtttggatca
    16381 accctgactg tggtttgaaa acacgtggta tcccagaaac aaaagaaagc ttgatccgcc
    16441 ttgttgaagc agctaaagct gcgcgtgaga aattgtaaga ttggatttct ctccatacag
    16501 tggttgttca aaaagaaatc aactagaaaa ggttattaca tatgtcacgc caaacaccgt
    16561 cactctcatt tgaagtgttc cctccaaacc cagccgtggg taatggtaac attatttcag
    16621 ccttgcagga tatgcaggag ttggctcccc attttatcag tgtaactgcc agcaataata
    16681 aatttaatat caaggaaacg acggttcgtt tggctgactt tatccaaaat gacttggcga
    16741 ttccgaccat tgcccacttg ccagctattt atctaactaa ggacaaggtt gctgaaacta
    16801 ttgttgactt ggacaaagtt ggggttcaga aaatcttggc tcttcgtggg gatattattc
    16861 cagacgtaga accacaaaag gatttccgct atgcaaccga cttgattgag tttatcaagg
    16921 aacaagcccc tcactttgat attattggag cttgctatcc agaagagcat ccagattcgc
    16981 caaatcagat ttcagatatt caaaatctta agaagaaagt ggatgcaggc tgttcgagcc
    17041 tcgtaactca gctcttcttt gacaatgagc gcttctatga ttttcaggac aagtgtatct
    17101 tggctgggat tgatgttccc attcatgcag gaattatgcc aattctgaat cgaaatcagg
    17161 ctctccgact cttgaagact tgtgagaata tccatcttcc acgcaaattt aaagccatct
    17221 tagacaagta tgagcatgac cctgagtcgc tcagagcagc aggacttgcc tatgcagtgg
    17281 accaaatcgt ggacttggta actcaggatg ttgccggtgt gcatctctat acgatgaata
    17341 atgctgatac agcaaaatac atccatcaag caacccatgc cttgtttaat caccagtctc
    17401 taggataata aaagcaaacc attcttctca ggtgagggga atggttcctt tttaatggta
    17461 aagacctcac tttttaagaa aaatatgata aaataaattc tgtacgtact tgatacaaag
    17521 atgaaggtat taaataatac aatgcattta aactgtaaga tttaacgaca cgagtgagtc
    17581 aaatcgatgt tatttgacga gagagttagt aaagcattta gctaatcgcc cgatagcgat
    17641 tagcgtgaaa gctttagata ctttagtatt aaacctttct aatgatgtat cttgaaaact
    17701 gaacttgcct acaactctgt ggaaaaagat aaatctccct aggagtagtc gctccgtcgt
    17761 tcgatttcct atcttccttt gagttgcttg acggcttggt atcttgagta attgaacacg
    17821 gccgaaaagc tgtgtaaaaa agataaactg tcttgtcttc atcgaagact tcgtcagttt
    17881 cctattttta ctttgctttt gacgtccttg gtatcttgat ctttgtaggc aaggcgtata
    17941 atttcatcaa tcaaaagggg attaaaatgg caaaacaagt gtttcaaacg acttttgcgg
    18001 gtcgtgagtt aattgtagag actggtcagg ttgctaagca agcaaatgga tctgttgtcg
    18061 tacgttacgg tgagtcaact gtcttgactg ctgccgttat gtctaagaaa atggcaactg
    18121 gggatttctt cccactccaa gtcaactacg aagaaaaaat gtatgcggct gggaagtttc
    18181 ctggtggctt tatgaaacgt gaaggacgtc cttcaacaga tgcgaccttg acagcgcgtt
    18241 tgattgaccg tccgattcgt cctatgtttg cggaaggttt ccgtaatgaa gtccaagtca
    18301 tcaatacagt gctttcttat gatgaaaatg catctgcacc aatggctgct atgtttggtt
    18361 catctttggc actgtctatt tcagatattc catttgacgg accaattgct ggggtacaag
    18421 tgggatatgt agatggccaa atcatcatca acccaagtca agaacaagca gagcaatctc
    18481 ttcttgaatt gacagtagct ggaaccaagc acgctatcaa catggtagag tctggtgcca
    18541 aagaattgtc agaagaaatc atgttggaag cgcttcttaa agggcacgaa gctgtcaaag
    18601 aattgattac cttccaagaa gaaatcgttg ctgctgtcgg taaagaaaaa gcagaagtgg
    18661 aattgcttca cgtggatgct gaattgcaag ctgaaatcat tgcagcctac aacagtgacc
    18721 tccaaaaggc agttcaagta gaagagaaat tggcccgtga agctgcaact caagcagtga
    18781 aagaccaagt gactgccgtt tacgaagaaa aatatgcgaa ccacgaagaa tttgaccgta
    18841 ttatgcgtga tgtggctgaa atcttggaac aaatggaaca cgcagaagtg cgacgtttaa
    18901 ttacagaaga caaggtgcgt cctgatggtc gtaaggtcga tgaaatccgt cctttggatg
    18961 cggttgttga cttccttcct cgtgtacatg gttcaggtct ctttactcgt gggcaaactc
    19021 aagctctttc agtcttgacc ttggctccga tgggagaaac tcaaatcatt gatggtttgg
    19081 atccagagta caagaaacgc tttatgcacc actataactt ccctcaatat tctgtagggg
    19141 aaacaggtcg ttacggtgcg ccaggtcgtc gtgaaatcgg tcacggtgct cttggtgagc
    19201 gtgctcttgc tcaagtcttg ccaagcttgg aagaattccc atacgctatc cgtctagtag
    19261 cagaagtttt ggaatcaaac ggttcttcat ctcaagcttc tatctgtgcg ggaactcttg
    19321 cccttatggc tggtggtgtg ccaatcaagg cgccagtagc tggtattgct atgggactta
    19381 tctcagatgg aaataactac acagtattga cagatatcca aggtttggaa gatcactttg
    19441 gagatatgga cttcaaggtt gcaggtactc gtgatgggat tacagccctt caaatggata
    19501 tcaagattca agggattact gcagaaatct tgacggaggc tcttgctcaa gccaagaaag
    19561 cgcgttttga aatccttgat gtcattgaag caaccattcc agaagttcgt ccagaattgg
    19621 ctccaactgc tccgaaaatt gatacgatca agattgatgt ggacaagatt aagattgtca
    19681 tcggtaaggg tggagaaacc atcgacaaga ttatcgctga aacaggtgtt aagattgata
    19741 tagacgaaga aggaaatgtg tctatctact ctagtgacca agatgctatt aaccgtgcca
    19801 aagaaattat tgctggtttg gttcgtgaag ccaaagtgga tgaagtttac cgtgctaaag
    19861 tcgttcgtat cgagaaattt ggtgcctttg ttaacctctt tgataagaca gatgcccttg
    19921 ttcatatctc tgagatggct tggactcgta ccaatcgtgt agaggatttg gtagaaatcg
    19981 gggatgaagt tgatgttaag gttatcaaga ttgatgaaaa aggccgtatc gatgcctcta
    20041 tgaaggctct tctacctcgt ccgccaaaac ctgagcatga tgaaaaaggt gaaaagtctg
    20101 agcgccctca ccgcccacgt catcaaaagg atcacaaacc taagaaagaa tttacagaaa
    20161 caccaaaaga ttcagaataa gaaaaggaga aatgtatggg gtggtggcgc gaaaccattg
    20221 atattgtaaa agaaaatgat ccagcggccc gcaccacttt ggaggttttg ctgacttatc
    20281 caggtgtcaa ggccttggcg gcccaccgtc tctcgcattt tctctggaag cacggcttca
    20341 aactattagc tcgtatgtac agtcagtttt ggcgcttttg gactcagatt gagattcatc
    20401 caggagccca gattgattca ggtgttttta ttgaccatgg ttctggtctg gtgattggag
    20461 agacagcgat tgttgaaaaa ggcgttcttc tctatcacgg agtgactctc gggggaacag
    20521 ggaaagactg tggcaaacgc catccgactg tacgaaaggg agccctcata tcagcccatg
    20581 cccaagttat cgggcctgtg gaaattggtg aaaatgccaa ggtcggtgct gcagcagttg
    20641 tcgtagcaga tgtacctagt gacgtgacgg ttgtcggtat tccggccaag attgtccgtc
    20701 ttcatggtaa gaaagatgag cctgtcattc acgaagtcga agaaaaacga gagtattatg
    20761 tcaataaact cgagcaggct aaagatgcca gtcacagatc gtctggtttg tagaggatac
    20821 ctatatgatt caagcaagaa acaagttaag ccaagaggag ctatctgaag cgaaaaaagt
    20881 aattaactgt tgccaaaact atgacggtac ctatcgcgat ccctatctct ctaacatgct
    20941 taattttgac ccaaacatgc ccgccttttt cctttattat gaaaaaggcg aacttgttgg
    21001 tttattaact gtctatgcag atgaccaaga tgtagaagta acgatactgg ttcatccagg
    21061 tcatcgccgt caggggattg cgcgtgcatt gtttactagt tttgagagag aaatagcttc
    21121 tttccccatt cggtcagtca cttttcagac agaacgtatt tttttagaga atcatcctga
    21181 ctttgccagt aactggggac taatcgagga tgaagagaca gaaacttggt taggtaagga
    21241 tagaagacct tatccgttag caaatgtttc ccatcttgaa gttttgttag cagatagttc
    21301 gtatcaggat caaattagtc aattaaaatt tcaggcattt tcagaggaac atgaatcgag
    21361 agaagttgtg gatagatatg tcgctgaagc tctgaaggat ccagaaagtc gcttatatat
    21421 tttattaaaa gacggtcagg ttattgggac ttgtacggtt gatttatcga ctaatacgaa
    21481 ttacttctac ggtttagcaa tattggaacc tgaacgtgga aaaggctatg gaagctactt
    21541 agcaaaatcc ctcgtcaacc aactaattga gcaaaatgac aaggaatttc agattgcagt
    21601 ggaagatagc aatgtaggtg ccaaacgttt gtatgaaaaa attggctttg tcaaacagac
    21661 tcaggtggtt tatctgaatg agaaaggagc aagggattcc gaagtgtaga gatattcgga
    21721 ctgaaattta cttgaacttt tagtgatgaa actaattgtt cttggatttc agctttcctg
    21781 attatgattt atgattaaaa tctatgacac catgtctcgt gatttgcgag aatttgtccc
    21841 gattgaggac ggcaagatca agatgtatgt ttgtgggcca acggtgtaca actatatcca
    21901 cgtgggaaac gcccgttcga cggtagcttt tgatacgatt cgtcgctatt ttgagtaccg
    21961 tgggtataag gttgcctata tttccaattt tacagatgtg gatgataaga ttatcaaccg
    22021 tgccagggaa gaaggcatca cgcctcagga ggttgcggat aagtacatcg ctgcctttcg
    22081 tgaggatgtg acggccttgg gcgtgaaacc tgcgactcgc catccgcgtg tagtggagtt
    22141 tatggcagac atcatccgtt ttgtggaaga cttgatcgag aaaggctttg cctatgagag
    22201 tcaaggggat gtctatttcc gtgtagaaaa atcccacaac tatgctaaat tggctaataa
    22261 aaccttggaa gatttggagc taggtgcttc aggtcgtacc gatgaagaaa cggctcgtaa
    22321 ggaaaatcct gtagactttg ctctatggaa atcttccaaa ccaggtgaga tttcttggga
    22381 tagtccttgg ggacctggac gtccgggttg gcatattgag tgttcagtca tgtcgacaga
    22441 gattttaggt gataccattg atatccacgg tggtggagct gacctagagt ttccacacca
    22501 caccaatgaa attgcccaat ctgaagctaa aacaggcaag gcttttgcta actactggat
    22561 gcacaatggc tttgtcaata tcgacaatgt caaaatgtct aagtccttgg gtaacttcat
    22621 tacggtacac gatgccctta aaactcttga tgggcaagta cttcgtttct tctttgcgac
    22681 ccagcactac cgtaagccta tcaacttcac ggaaaaggca gttcgcgatg ccgagaccaa
    22741 tctcaagtat ctgaagaata cttacgaaca accatttaca ggaaacgtgg atgcccaaga
    22801 gttacaaaac tttaaagata agtttgtagc agctatggat gaagatttta atgctgccaa
    22861 cggtatcaca gttgtctttg aaatggccaa atggatcaac tcagggaact atgatgcaag
    22921 tgtcaagcaa gctcttgcag atatgttaga aatttttgga attgtctttg ttgaggaagt
    22981 tttggatgca gagattgaag acttgattca aaaacgccaa gaggcgcgtg ccaatcgaga
    23041 ctttgagaca gcagaccaaa tccgtgacca attggttact caaggaatta agctccttga
    23101 taccaaggat ggagtgaggt ggacacgtga ttgatgtcaa tctcattaac gggattgcgc
    23161 tagcctttga gggggatgcg gtgtattcta tgtatattcg ccgtcacctc atcctcaaag
    23221 gtatgaccaa acccaataaa ctccatcaag aagcaaccaa gtatgtgtca gccaaggctc
    23281 aggctcgcct gattgctctc atgttggagg agcaggtcct aacggaaaaa gaagaagaaa
    23341 tctacaaacg tggccgcaat accaatagcc acacaaaggc taaaaatgca gatgtcgtga
    23401 cttatcgtat gtccacggga tttgaagcgg ttatgggcta tctccatatg actgagaatc
    23461 tggaacgtct tgagagtttg gtttcatggt gcatccaaaa agtggagggc tagaacatga
    23521 gggaaaaaga actacaagac tggtttcctg aggctcggat ttcagaccaa ccagtagaga
    23581 aagagggcta tctcacgctc cctttagctt ctcagcagtg gattttgctg gaggaagctg
    23641 ggctcagcga gcgtgaaaag cagttggttg cccttttgac ccagcaggag caggctcgtt
    23701 cgctaaaccc ttggtattcc tatctggttg aaggcaaggg acaggcaccg caagttttta
    23761 aaaagattca gttggtttat tgccatcttt cttattttca gcaggaaaat ctggcttctt
    23821 ggctagatat gatgcggact ctttttccga attgtcagac agtgctacag gtcggatctc
    23881 aggattatgt tttcgtgctt caacaagaca aatacactta tgtaagagat attttaagtg
    23941 atacgattga agcggttgag tatgactttg gacttcgtct ttctatcatg ttgggtcagg
    24001 tttggtctca gacgggacat caagccctat cagacttaat caaagctgag cgggatttgt
    24061 tcaagacatg gtggcgtcag ggtcaccaag gtgttcatac tttttctcag ctctatcttt
    24121 ggagtatggg agaaagactc gtggacttga agccaatcaa ggaatgtcta caccagatga
    24181 ttttggatca agatcagatt caggaaatca ttctctctct ttgggaaaat agtgctgttc
    24241 tcactaaaac agcccagcaa ctctatctgc accgcaattc tctccaatac aagattgata
    24301 aatgggaaga gttgacaggg cttcagttga aagagttgac cgacctgacc ttgtgttatc
    24361 aattgatttt aggttctttg tcaactatag ttggtttgta aagaagttaa tatttggaga
    24421 agaggatggc catcttctcc atttttatgt gcagagttat agtggcttga tgctgggaaa
    24481 gtacactgtg actgctaaaa cattcctaga agttgctttg atttccctaa tctatttatg
    24541 tgaattttat gttattttac tataacagtt gttgctaagc taaataatag tggggaagtt
    24601 tatttagacg taagcattga agataatcag ggaggtagtg ggtataattt cagttctgtt
    24661 tcaagtagct cacaaacagc taaatatgaa ggaactggtt ataataacaa ttcatcatta
    24721 tatataacga ttgataaaac gtctgatgca acagctcttt tgaaattaaa gttgaataat
    24781 gttgataatc aacctgctac tgaagttcct agttcaggaa ttactgtaaa attaaatgct
    24841 aaagataatg ctggaaactg gacaagtgct tcgaataaaa aagaagtaac agtaaaaatt
    24901 gtttctgcta aaccgacata tccagacaaa attttagtga aaaatcctga taatataaaa
    24961 gatacagaaa aaaatgccat tattgaaaaa ttgaaagagg caaataaaaa tcatccagca
    25021 ggagctccaa cctttgctaa aggtgaagga gagcatgcaa atgatattgt agcaacttat
    25081 tcagatggta caacttatta tgtaccgtta aatgatgtga caaaatatgc gaggtagtgg
    25141 ctgtaccact cacttattca cctccccgtg atttgtagta gtgataggct ttctcactat
    25201 tattataaaa caaaataaag atcacaacac tttttcattc tgtgttgtgc cttgagtgaa
    25261 acgaaaggaa tgaattataa atatgaaaag tatagtcact aacatagatg agcgcttgcg
    25321 tactcgccta cgagtgatta tctggaagca atggaagaag aaatcgagac gattatgggg
    25381 attgcttaag ttaggggttc ctaaatggat agcagataag gtatctggct ggggcgagca
    25441 ctatcaatta tattaaaatg aaataagaat aggacgaatc gatcagggaa gtcaaatcga
    25501 tttctaacaa tattttagaa gtagag
//
LOCUS       DAVBOM010000031        24519 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBOM010000031 DAVBOM010000000
VERSION     DAVBOM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.031"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(98..2356)
                     /locus_tag="VQ878_001326"
     CDS             complement(98..2356)
                     /locus_tag="VQ878_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3095662.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VQ878_001327"
     CDS             complement(2585..2815)
                     /locus_tag="VQ878_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET3095663.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VQ878_001328"
     CDS             3005..3688
                     /locus_tag="VQ878_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3095664.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VQ878_001329"
     CDS             3688..4422
                     /locus_tag="VQ878_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3095665.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VQ878_001330"
     CDS             4576..5433
                     /locus_tag="VQ878_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET3095666.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VQ878_001331"
     CDS             5575..6447
                     /locus_tag="VQ878_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET3095667.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ878_001332"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ878_001332"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET3095668.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VQ878_001333"
     CDS             7426..8637
                     /locus_tag="VQ878_001333"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET3095669.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VQ878_001334"
                     /pseudo
     CDS             8639..9181
                     /locus_tag="VQ878_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9197..10006
                     /locus_tag="VQ878_001335"
     CDS             9197..10006
                     /locus_tag="VQ878_001335"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3095670.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..11213
                     /locus_tag="VQ878_001336"
     CDS             10482..11213
                     /locus_tag="VQ878_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095671.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGK"
     gene            11259..11462
                     /locus_tag="VQ878_001337"
     CDS             11259..11462
                     /locus_tag="VQ878_001337"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3095672.1"
                     /translation="MDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRT
                     DTAQDRLANFDVILLDSSGKEIE"
     gene            11487..11999
                     /locus_tag="VQ878_001338"
     CDS             11487..11999
                     /locus_tag="VQ878_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET3095673.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12657..13367
                     /gene="deoD"
                     /locus_tag="VQ878_001339"
     CDS             12657..13367
                     /gene="deoD"
                     /locus_tag="VQ878_001339"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3095674.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13390..13914)
                     /locus_tag="VQ878_001340"
     CDS             complement(13390..13914)
                     /locus_tag="VQ878_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET3095675.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13967..14203)
                     /locus_tag="VQ878_001341"
     CDS             complement(13967..14203)
                     /locus_tag="VQ878_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET3095676.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14271..15191)
                     /locus_tag="VQ878_001342"
     CDS             complement(14271..15191)
                     /locus_tag="VQ878_001342"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET3095677.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15389..15793
                     /locus_tag="VQ878_001343"
     CDS             15389..15793
                     /locus_tag="VQ878_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095678.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16009..16590
                     /locus_tag="VQ878_001344"
     CDS             16009..16590
                     /locus_tag="VQ878_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3095679.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16587..17864
                     /locus_tag="VQ878_001345"
     CDS             16587..17864
                     /locus_tag="VQ878_001345"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET3095680.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17882..18544
                     /gene="deoC"
                     /locus_tag="VQ878_001346"
     CDS             17882..18544
                     /gene="deoC"
                     /locus_tag="VQ878_001346"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET3095681.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18531..18920
                     /locus_tag="VQ878_001347"
     CDS             18531..18920
                     /locus_tag="VQ878_001347"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3095682.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19011..20063
                     /locus_tag="VQ878_001348"
     CDS             19011..20063
                     /locus_tag="VQ878_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET3095683.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20207..21742
                     /locus_tag="VQ878_001349"
     CDS             20207..21742
                     /locus_tag="VQ878_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095684.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21735..22793
                     /locus_tag="VQ878_001350"
     CDS             21735..22793
                     /locus_tag="VQ878_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095685.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22796..23752
                     /locus_tag="VQ878_001351"
     CDS             22796..23752
                     /locus_tag="VQ878_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095686.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23837..24519
                     /locus_tag="VQ878_001352"
                     /pseudo
     CDS             23837..24519
                     /locus_tag="VQ878_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7183 a         4406 c         5573 g         7357 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttcgtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc ttttatttgc
     3601 agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggaatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acttgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaatga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcatttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa ttatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggaactt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctagg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggatgctacc
    10741 tagctcagat tgcagaggtt gaagcttacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttggaatg
    10861 ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aatgatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa taggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa actttcaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaggataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgatagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 taggactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaataaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aagaaaggaa ttgaccccac cctaaaagca gtgggaaaaa
    12421 gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc ttcgcttttt
    12481 gatgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag agcgtgtgtt
    12541 ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa aatcaggatt
    12601 tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct ctttgtatca taaattatgt
    12661 ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt cctggggatc
    12721 ctcttcgtgc taagtttatt gcggagaatt tccttggtga tgctgtttgt tttaacgaag
    12781 tgcgtaacat gtttggttac actggtactt acaagggtca ccgtgtatct gtcatgggaa
    12841 ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta gactacggtg
    12901 tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt catgttcgtg
    12961 aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat gactggccac
    13021 agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac catatcgcca
    13081 aagaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc ttttactcaa
    13141 attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg gaaatggaag
    13201 cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct atcatgacca
    13261 tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt caaaatacct
    13321 tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta tagccaaaaa
    13381 ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat ctagctctct
    13441 ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt ggtaattttc
    13501 tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc agtcaaagcg
    13561 ttcagggcaa tctgccgcca tactttctct gacttttcca cggtatttaa gataacgctt
    13621 aaaggctcta aagagacagg tcaatggcaa aaaattgaga aagatgattt ggtcagcttc
    13681 ttgcattcgt tcttggtagt agcaccaaga ataattacca tcgatgaccc aagctttatg
    13741 cttggtgaga aagtttttta tctcggttaa catccattcg cagtcactgt cttgccaacc
    13801 aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt tagataactt
    13861 ttctgctaga gttgacttac cagaaccaga atatccgata attgtgattt tcattttcta
    13921 ccttttccta tttggagaca aaaaaacagc ctctatggac tgtttcttat ttagcaagtt
    13981 tagctgaaag acgagcttta tcgcggcttg ctttgttttt gtgaatcaaa cctttagttt
    14041 ctgctttatc gatagctgag ctagcagcac ggaaaagttc ttcagatggg tttgcttcga
    14101 aagcttttat agcagtacgc atagctgatt tttgagctga gttcttttcg ttttgtttaa
    14161 cgttcaattc agcgcgtttg atagctgatt taatgtttgc caatgttctt acctccatat
    14221 ttactaacta taccattata tatgaaaact tacgttttga caagggaaaa ttattttttt
    14281 aagtaaattt catcgatttc atggttcttg cttttatgaa gaatcacttc tgcacgattt
    14341 ctggttggtt caatataatt ttgtagattt gtgagattga tactggtcca gacctgatgg
    14401 gcaaaggctt ccacttcccc aatcggcatc tgagtaaaac gataatagta gctatcaggg
    14461 tcgttttggg ctaggctcag cattttcaag aaacggtcca gataccaact ttcaatatca
    14521 tccactccag catctacata gatggaaaag tcaaagaagt cagtgatata gagacgatcg
    14581 ttttgtggat tttgaaagac attgattccc tcaacaatta caaaatcagc agctttgaca
    14641 ctttgtttct cttcgggtac gatgtcgtaa acttcatgag aatagacagg aatatctaca
    14701 tcttgtccat ttttgatgcg gtccaagaag ttgagaagag cttccatatc atagctttca
    14761 ggaaatcctt tacgatttaa aatcccctgc tcaatcaagg tttgattggg atagagaaaa
    14821 ccatcagttg taaccaactc aaccgtagca tctgtaaacg tacgggacag taggatttga
    14881 agtaggcgac tggttgtgga ttttccaacg gcaacactcc cagaaacccc aataataaaa
    14941 ggttgagatt tactttcacg ttggaggaaa attccttttg aaaaggctaa atcttcctta
    15001 gttcgcttgt aaatctgaat cagatgagcc aaggggagat agatatctgt aacgtcttgg
    15061 agactgattt ggtcattaaa actcttgata gattccaatt cttcttctgt caaaggaggt
    15121 gttgtctttc gatgtaaaga ttgccaagtc tggcggctga ttttttcaaa atgtaaaaat
    15181 tcgttggtca tttgttttcc cctagatatt ttgtctatca taccataaaa atctaaaaaa
    15241 ataaagcggt ttcttgaatg tggtaagtca atggtatata gtataagtga tcaatttatt
    15301 gatgaaatag gagatagatt ctactgattt ataagtttat aagcttataa agggggcttt
    15361 ttagttcaca acttatagga ggtgtactat gaaaatctta aaacgttaca tattggaact
    15421 ctgttttatt ttaagttttg ctttaccttt tataaaagga gccaatgcag ataatggtat
    15481 atgctttgtg gaaacctatt acggttttac ttttttgatg gaacatgcta ttgtaacagc
    15541 tgtctttatc tattcgtttt taattgcttt cttactaaaa aaacgatggg cgaaatggat
    15601 tgctgctggt agttattgct ttttagtcct atggattgcg acagagggtt atttcttccg
    15661 catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga cacaaacgta
    15721 tcagttgggc ttttatctaa acattttgtt aggaattttg ttgataataa agtattttaa
    15781 ggttaagcaa tagaaataat aatctgcctg attatagatg ataaactttt tgtttttatc
    15841 tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga aagagattga
    15901 agaaaatggc ttcgtgactt gctttcttcg gtctttttcg ttttattatc aatttgtaaa
    15961 cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat gtattatgca
    16021 gaaaatcctg acgctgctca cgacattcat gagttgagag tagagttgtt gggacaaaaa
    16081 atgacctttt taacggatgc gggtgttttt agcaagaaaa tagttgactt tggaagtcaa
    16141 ctattgctca agtgtcttga ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt
    16201 tacggacctt tgggtttgtc cttagctaag gcttatggag ttcaggctac tatggttgat
    16261 atcaacactc gtgccttgga tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg
    16321 acgattttcc agtccaacat ctatgaacaa gttgaaggac attttgatca tgtcatttcc
    16381 aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcattgagaa aagtaaagat
    16441 ttcttggaaa ctggtgggga tttgacaatc gtcatccaga aaaaacaagg ggctccaagt
    16501 gctaagtcca agatggagga tgtgtttggt aattgtgaaa tccttaaaaa agacaaggga
    16561 tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatacaa aaaaaacgag
    16621 acggtcaaga actgacttca agtgaaattg aatggctggt agaaggctat gtgtcaggaa
    16681 ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa ggaatgacga
    16741 ctcgtgaaat ttctgattta acgatgaata tggttaagac tgggcaagag tttgacctgt
    16801 cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc gataaggtaa
    16861 ccttgatttt agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc
    16921 gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattaag ggctatcaag
    16981 tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta tctgtcattg
    17041 ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt gatgtgaccg
    17101 caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa attgcggcag
    17161 gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg aagacggttg
    17221 atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt ggacggaaga
    17281 cagtagcagt gattacggat atgagccagc ctttgggacg agcgattgga aatcgtctgg
    17341 aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt acccacttta
    17401 tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaaaact gttgaagaag
    17461 ttcaccaaca tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc
    17521 aaggtggaga cttggaagac ctctatcgtc ctgtaaatgt agctcatgtg gtggaaatcc
    17581 ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt ctttatgcca
    17641 tgaggctggg tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa acaggaattg
    17701 tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca aaagtataca
    17761 caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt aaaataagtg
    17821 atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag ggaaaaccga
    17881 aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa agaaaaaaca
    17941 aattgatagt ttgttgtctg aggctagaga gtatgacttt gccagtgttt gcgttaatcc
    18001 gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg tttgcacagt
    18061 agtaggtttc cctttgggag caacaacttc agccgtgaaa gcatttgaga caaaagaagc
    18121 tatccaaaat ggtgcagatg agattgatat ggtgatcaat gttggagctc tcaaatcagg
    18181 taatttagcc ttggttgagt cagatattcg cgcagtagtg gaagcaagtg gtgataagtt
    18241 agtgaaagtc attattgaag cttgccttct gacagaccaa gaaaaagttg ttgtttgcca
    18301 attggcccaa aaagctgggg ctgactttgt caaaacatct actggctttt caactggtgg
    18361 tgctacgata gcagatgtta cattaatgcg tgaaacagtt ggatctgata tgggtgtcaa
    18421 ggccgccggt ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac
    18481 ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag atggcgacta
    18541 ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc tattctcact
    18601 ttcctatcgg agcagtttta gtagctaaag acggaagtgt ttacacggga gtgaatattg
    18661 aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt aaggctatat
    18721 ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa aaaccgattt
    18781 caccatgtgg tgcttgtcgc caagtaatgg tcgaattttt tgaacaagat ttaaaagtga
    18841 ccttagtcgc aaaagataaa tcgacggtcg agatgacggt cggggagtta cttccatatt
    18901 cttttacaga cttaaattag tctgagtcgc tctttgagtg gcaagggtct ttgtgaccaa
    18961 tcaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    19021 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    19081 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    19141 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    19201 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    19261 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatctttg
    19321 gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac actgacttga
    19381 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    19441 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    19501 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    19561 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    19621 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    19681 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    19741 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt gaccaagaag
    19801 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    19861 tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa ggagaattcc
    19921 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    19981 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    20041 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    20101 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    20161 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    20221 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    20281 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    20341 gtccacgcta atgaacatgt tagcagggct tcttgaacca actagtggtg aaatcgcggt
    20401 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    20461 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    20521 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    20581 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    20641 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    20701 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    20761 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    20821 tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    20881 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtagggcgtt ctgtttcctt
    20941 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    21001 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    21061 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    21121 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    21181 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    21241 tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    21301 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    21361 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    21421 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    21481 tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    21541 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    21601 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    21661 atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    21721 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    21781 ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    21841 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    21901 gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt cgagctggtt
    21961 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    22021 cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    22081 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    22141 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    22201 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    22261 atgcaactta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    22321 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    22381 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    22441 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    22501 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    22561 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    22621 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    22681 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    22741 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    22801 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    22861 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    22921 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    22981 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    23041 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    23101 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    23161 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    23221 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    23281 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    23341 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    23401 atatttaggg attattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    23461 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    23521 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    23581 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    23641 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    23701 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    23761 aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa aatctaactt
    23821 ttggggtgtt tttattatga aactaactta tgatgataaa gttcagatct atgaacttag
    23881 aaaacaagga tatagcttag agaagctttc aaataaattt gggataaaca attctaatct
    23941 taggtacatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa aaggaaaaaa
    24001 tcgttactat tctcctgatt taaaacaaga aatgattcat aaagtctgac atgaaggcta
    24061 gactaaagat agagtttctc ttgaatacgg tctcccaagt cgtacgatac ttcttaactg
    24121 gctagcacaa tacaggaaaa acgggtatac tattgttgag aaaccaagag ggagagtacc
    24181 taaaatggga cgtaagccaa gaacgagacc tgaagagagg acagaattag aacgtcttca
    24241 agcagaaaat gagtacctga gagcggagaa tgccatccta aaaaagttaa gagaactccg
    24301 attgaaggag gaaaaagaga aagaagaaag atagaaattg ttcaagaatt aatgactgag
    24361 ttttcgttag atcttcttct aaaagccatt aaactagctc gttggaccta ctactatcac
    24421 ttgaaacagt tagacaaacc agataaggac caagagctta aagctgaaat tcaattcatt
    24481 tttatcgaac acaagggaaa ttatacttat cgccgggtt
//
LOCUS       DAVBOM010000032        22634 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBOM010000032 DAVBOM010000000
VERSION     DAVBOM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.032"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(339..1319)
                     /locus_tag="VQ878_001353"
     CDS             complement(339..1319)
                     /locus_tag="VQ878_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET3095687.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ878_001354"
     CDS             complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ878_001354"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET3095688.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3669..4772)
                     /locus_tag="VQ878_001355"
     CDS             complement(3669..4772)
                     /locus_tag="VQ878_001355"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET3095689.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4762..5130)
                     /locus_tag="VQ878_001356"
     CDS             complement(4762..5130)
                     /locus_tag="VQ878_001356"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET3095690.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5169..6200)
                     /locus_tag="VQ878_001357"
     CDS             complement(5169..6200)
                     /locus_tag="VQ878_001357"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3095691.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6202..7233)
                     /locus_tag="VQ878_001358"
     CDS             complement(6202..7233)
                     /locus_tag="VQ878_001358"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3095692.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ878_001359"
     CDS             complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ878_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET3095693.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTLERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9973..10262)
                     /locus_tag="VQ878_001360"
                     /pseudo
     CDS             complement(9973..10262)
                     /locus_tag="VQ878_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10290..10922)
                     /locus_tag="VQ878_001361"
     CDS             complement(10290..10922)
                     /locus_tag="VQ878_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3095694.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10926..11567)
                     /locus_tag="VQ878_001362"
     CDS             complement(10926..11567)
                     /locus_tag="VQ878_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095695.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11560..12351)
                     /locus_tag="VQ878_001363"
     CDS             complement(11560..12351)
                     /locus_tag="VQ878_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095696.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            complement(12536..12871)
                     /locus_tag="VQ878_001364"
     CDS             complement(12536..12871)
                     /locus_tag="VQ878_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095697.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13011..13346)
                     /locus_tag="VQ878_001365"
     CDS             complement(13011..13346)
                     /locus_tag="VQ878_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095698.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ878_001366"
     CDS             complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ878_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET3095699.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14761..15474)
                     /locus_tag="VQ878_001367"
     CDS             complement(14761..15474)
                     /locus_tag="VQ878_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET3095700.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKPRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15471..16367)
                     /gene="dnaI"
                     /locus_tag="VQ878_001368"
     CDS             complement(15471..16367)
                     /gene="dnaI"
                     /locus_tag="VQ878_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET3095701.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16368..17537)
                     /locus_tag="VQ878_001369"
     CDS             complement(16368..17537)
                     /locus_tag="VQ878_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET3095702.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17538..18011)
                     /gene="nrdR"
                     /locus_tag="VQ878_001370"
     CDS             complement(17538..18011)
                     /gene="nrdR"
                     /locus_tag="VQ878_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET3095703.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18151..18516
                     /locus_tag="VQ878_001371"
     CDS             18151..18516
                     /locus_tag="VQ878_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3095704.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18521..19216
                     /locus_tag="VQ878_001372"
     CDS             18521..19216
                     /locus_tag="VQ878_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095705.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19233..20000
                     /locus_tag="VQ878_001373"
     CDS             19233..20000
                     /locus_tag="VQ878_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095706.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20353..21552)
                     /locus_tag="VQ878_001374"
     CDS             complement(20353..21552)
                     /locus_tag="VQ878_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095707.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21549..22442)
                     /locus_tag="VQ878_001375"
     CDS             complement(21549..22442)
                     /locus_tag="VQ878_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095708.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
BASE COUNT         6646 a         5104 c         4193 g         6691 t
ORIGIN      
        1 tttttgaaaa gtattaacac ctacagacaa gcctgacgat agcaagaact accctactcg
       61 ataggtatcg gcttttgctt tctgaaaaaa attattttaa gcaatttgac aaatctagca
      121 acaaaaaatt ttataaatac aatagattga aactagaata gtacaccttt gcttctaaaa
      181 cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgtttttat ttcattttac
      241 tatatttcca tgataaaacg catagtatca agttttctta atcccctgat actatgcgta
      301 tttgtaattt ttaagatttt gtgcttagag tcgactcctt attttagata tttaaaagga
      361 atctcactcc cacagagcca gttgtagact tggtcatcga caaatacatt catggcttcg
      421 tgagcatact caggcatgat gcgataggtt ttatcgcagg tcagacgatt ataaatcgca
      481 aactgggtaa tgggatagca aacatcgtcg tccaagcccg taatcatctt aacctcacct
      541 tggatacgat gggcaagatt tttgacatcg atataggcaa gggtcgccat gatttcctcc
      601 tctgtttcat ggaaggggtc gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg
      661 ctagtattac caatctcaat cacccgtctg aagtctgaca agaagggata aatggcaact
      721 gttttctgaa ttcgaggatt gagcgctgct gcaactagag ctagagcccc tccttgtgag
      781 gcaccatagc tagaaagacg cttctcatca acctgagaca gactagcaac aatttcgacc
      841 aactggtaaa tatccagata aacatcctta taaaagaggt ggtcccgacc ttccatagca
      901 ccacggataa tatgcccctt cacggtattt cctaaaggag aacgcaagcc gtcttgtgag
      961 taacctgact ggccccgcac atccatggaa acaacaccgt aaccagctac ggtgaagccc
     1021 agcatgtcgg cccagtccca gccacgtccc atataaccat gaaaatggaa gattagtgga
     1081 accttctcct cactctttgg aagaacaatg cgtgcataga cctttccttc cttgcttcct
     1141 tcaaatgtta actcatagca cttgacttga ggaatgtgga aatctctttc ctccaagtgg
     1201 taggatggaa gcgtggaaac atttttcact tccccatccc agaaagcatc aaagtcttcc
     1261 ggaacctcat cccttcctct ataggtctta atttcttcta gcaaagctgg atttttcata
     1321 gcatgctcct tttattttgt aatcgttacc acaactgtag catatctatg taatcaatgc
     1381 aagaaagaag gataaataga aagtgaattt agattcttta cttttaggat gataggctga
     1441 aagtagtttt agaaacgaaa aagagcattt cgctctctct tctgtttata ctagtttttt
     1501 gcttccttct tttggaaagt ggtttggtaa tttactttaa tcgttactgt catatgagag
     1561 tcctcgtttc tttttgatga ctttagtata agagccaaac ctaaaaacta gcttaagttt
     1621 tccttagaga aagcttaatc cagatgttct ttcttttcca gatgaagggc aatcatgcgc
     1681 cactctggat cttcttgcca agcttctata gaactaatgt agctagcaac ctttcttgct
     1741 tcttctaaaa tcggaaaatc ttcgataata tcagccactt ggaactctgg aagtcctgac
     1801 tgtctggttc caaaaatctc accagaacca cgcattttca aatcttcctc cgcaaggaca
     1861 aatccattgg tcgtttctgt catgatacgc atgcggtctt tcccagaatc cgtcttggga
     1921 ttagcaacga gaacagcgta ggactgcttg tccccccgac cgacacgacc tctaagctgg
     1981 tgaagttgac tgagaccgaa gcgatcggca tccatgataa tcatgacagt cgcattggga
     2041 acgttgaccc caacctcaat aaccgtcgtc gaaaccagaa tatccgtctt tctctccttg
     2101 aaatcctgca tgatctggtc tttttcgtca ctcttcatcc taccatgtag aagagccacc
     2161 tctgccttgc ctgcaaaatg agtcgtcaac tcctctgata aggcaatggc atttttcaaa
     2221 tctagagctt ctgattcttc aatcaaagga gagatgacat agacttggga acctttttga
     2281 atttccccct ctaaccaagt caagacctga ggtagttgct catgtttgat ccagcgcgtc
     2341 acaataggct tccgacctgc tggcatctgg tcgataatgg aaacatccat atctccaaag
     2401 gctgtgatgg caagcgtccg tggaatggga gtcgccgtca tcatgaggac atctggattg
     2461 tcaccttttt cccgtaaaat acgcctttgc cctacaccaa aacggtgctg ctcatcgata
     2521 ataatcaaac caagacgagc atactccacc ccatcttgta tcagagcgtg agttcctata
     2581 atcaaatcag cctcaccctt ggcaatggtc tccaagactt ctctcttttc tgcagctttc
     2641 aaggaacctg tcaagagagc cagtttcaaa ttgggaaaaa ggttctgtaa actctcaaag
     2701 tgttgctctg cgaggatttc tgttggtacc attagggcag cctgataacc tgctgtcact
     2761 gccgcaaaca tggccaagcc agcgactacc gtttttccac tccccacatc cccttgtagg
     2821 agacgattca tgtggtggtc ggacttcata tcagttaaaa tttcctgcaa actcttttcc
     2881 tgagcttggg tcagggcaaa aggaagactt actttaactg ctgtcacttt ttcctgagac
     2941 caattcagaa ccagaccact tccctgaact ctattttcag acttgagcat ctgcagctgc
     3001 atttggaaat aaaagagttc ctcaaacttt atacggcgaa gagcctgctt gtattctgcc
     3061 aaatactttg gaaaatgcat agcacggact gcctgacaac gggacatgag tttgtatttg
     3121 tctagtaaag actggggcag attttcttct atcaagaggt ccagtccctg atcaaaagcc
     3181 gtcttgatga ccttgaccag actggcctgg ctgattccct gagccagacg atagacaggc
     3241 tggaggtcat cttctacctg agccagaacc ttcatcccag tcagactagc cttagcgcgg
     3301 tcccattttc caaagacagc aagggttgct cccaactcta ttttatcagc cagatagggc
     3361 tggttaaaga aattcaccgc aaaaacgacc tctccctgct tgagactaaa acgcaggcga
     3421 ttgcgcttga aaccataata ctggacacta gcaggagtca ctacctgacc agaaagaact
     3481 gccttctcac cgtcttccag ctccagcacc tgcttggttt tgaagtcttc ataacggaaa
     3541 ggaaagtaga gcaagagatc ttgcaagttt tcaattccta gtttggcgta tttttctgct
     3601 gactttggtc ccacaccagg caagacatgc aagggttgat gtagattcat gctccactcc
     3661 tttcttttct aataatattc tctcggaata cggtcgctga ggaggcaaac cacctcatag
     3721 ttaatggtta cgcggtaggt cgctacctga gttgcagtga tttccttatc cccattggag
     3781 ccaatcaagg ttaccttggt tcctagcgga taaagcttag gcaatcgaat agtgatttgg
     3841 tccatcgaaa ccctgccgac aattgggcaa gcttggccat ctaccaagac agagaaattt
     3901 tgcatgtctc ttgtccatcc atctgcatac ccgattggca cggtcgcgat gacttgctcg
     3961 ctatccgctt gataagttgc tccatagccc atgcaagctc cagctggaac tgtcttgaca
     4021 tgaaccagag cagactccaa ggtcaaggcc ggtatcaaat cataaggcaa atccaagacc
     4081 gctccacttg gattgaggcc atacatggca tctcccatac gaaccgcatt gaaaatagtc
     4141 tctacatgcc aaagagtcgt tgcagaattg ctagcatgaa ccagctctgg aacttccttc
     4201 atactagcta aaatagtttt aaaccgttct aactgggcat taaaatagtc atctgattcc
     4261 tcatcagcag tagcaaagtg ggtaaagatt ccttcaacac aaacaccgtg ttgttggagc
     4321 aaatcttgag cctgctcaac ctcacttgcc tctctaaaac caatccgtcc catccctgaa
     4381 tcaatcttga ggtggactgt caatccagtt aggtccactt ccttatctaa gagtgcttga
     4441 atccactcca gtccagccac tgtcaaggtg aagtcatatt ctttagctag agcaacagct
     4501 tcgatttcag aaactcctaa aatgaggatt ggcttgctga gtccagcttg tctgagttca
     4561 atggcttcat cgatattgga aacgcaaaag ccatcaacat catcttgaat tgccttggca
     4621 acggcaacag ctccatgacc ataagcattg gccttaacca cagccaactt gagcgttcct
     4681 tgagggatat gagcccccat ttgctgaata ttttgtcgaa tagctcccag atgaatcaga
     4741 gccttggttg gtctatgtgg actagctttc atgattttcc tccaaaatga cactggctgt
     4801 cacaaactga tcggtgtggc tgatagacag ccaaatcttt cctgaaaatg gtgcctgact
     4861 aaaataaggc gccccacgtt cattgttcaa gacttccaaa tcctgaaaac cgagcttgct
     4921 aatgcccgtt cccatagcct tggaaaaggc ctccttagcc gaccagcgac cagctaaata
     4981 ttctatttgc ctgcgtcctt tgagactggt gaagcgctcc atttcctgag cggtcagtac
     5041 acgcttagca aatccttcat gtcgtgtaac tgcgctttct atcgaagcca attcttcaat
     5101 gtcaattccg tgtccaacta tcattctcat caaaaggagt tgagattccc caactccatc
     5161 cttttcactt attttgtcaa ggtaacataa atctcttcta ccaaggcctc tgtattttcc
     5221 caacctaggc aagggtcagt aatagagcaa ccaaagatct ctggttggtt ttgacgacca
     5281 tctgctaggt aagattcaat cataaatcct cgaaccgtct ttttaatttt ctcattccaa
     5341 tcacgattct gcaaggtctg gcgaacaatt cgaatctgct ccatatattg cttgcctgag
     5401 ttatcatggt tggtgtcaat gaggataaaa ggattttcaa gtcccatggt ttcatagcgt
     5461 tcaatggctt ggagtagatt ttcatagtag taattcggca tataattgcc atactcgttg
     5521 actgctccac ggaggataac atgggccaaa ggattacctg atgtctcaac ttcctgccca
     5581 tgataaagga aggtttgctt gttttgagca gcatagatgg cgttaaacat aacacccaaa
     5641 tttcctgagg ttggattttt catccctact ggtgcatcaa tcccagaagc cacaaagcgg
     5701 tgctcttggt cttccacaga acgagctcca acggcatggt agctgaccaa gtcatccacc
     5761 aagatcagat ttgacggata aagcatctca tctgccgttg tcaaaccagt ctctgtaatc
     5821 acgcggtagt gcaactggcg cacagcctgc aagccattaa tcaggcttgg agccttagaa
     5881 gtatctggct ggtgaactaa tcctttatag ccgtctccat tggtacgagg cttagcagta
     5941 tacacgcgca tgaccatgaa aatcttatcc gctaccttct tttgcaaggc agataaacgg
     6001 cgagcatatt ccaagaccgc ctcttcatta tcagaagagc aaggaccaat caccaagaga
     6061 atacggtcat cttcccctga aataatatct gccaattccc tgtcacggct ttccttgagt
     6121 ctcaaggctt ccgcagacaa ttgggtttca gccttgatga cttccatatc gatttcttga
     6181 cctttttcaa taaatgccat cttattctcc taacgttttg taaatttctc tgacaagagc
     6241 ttctgtgtta tcccaaccca ggcaagggtc tgtgatagac ttaccaaata cttctggctc
     6301 attttgtcga ccatcttcca gataagactc aatcataaaa ccacgaacga actgcttaat
     6361 tttttcattc caagcacggt taatcaaggt ctggcggaca attcggatct gttcaatata
     6421 ctgcttacca gaattgtcat gattggtatc aatgatgata aaaggatttt ccaagcccat
     6481 tttctcatac tgggcaatgg tatcaattaa attgtcataa tagtagttgg gaatattttt
     6541 tccatactca ttaagagcac cacgaagaat agcgtgtgaa agcgggttcc cagttgtttc
     6601 tacttctttt cctaagaaaa ggaaactttg tttgttttga gcagcataaa tcccattaaa
     6661 catgacattg agatttccag aggttggatt tttaaaacca gtagaaaatc ctgccccact
     6721 tgccacaaag cggtgttgct ggtcttcaac tgaacgggca ccaactgcca tgtaagaaat
     6781 caaatcatct acaagcggaa ggttttcagg ataaagcatt tcatcagcag ttgtcatccc
     6841 tgtttctgtg atgacacgat agtgaagatg gcgaacggct ttgattccat tgataagact
     6901 aggcgcttct gtcgcgttag gctggtgaat caagccctta tagccatctc cgttggtacg
     6961 gggtttggca gtataaacac gcataaccat aaagatacga tctgccactt cttcttgtag
     7021 gactgccaaa cgcttagcgt attcaaggac agcttcttcg ttgtcagatg agcatggccc
     7081 gattaccaag agaattcgct ggtcttctcc acgtataatg gcttctagct cttgatctcg
     7141 ctgtgatttc ctctccaaag cctgaccttc taattttgac aaggcacgaa cttcttctat
     7201 atttatttta gagctttttg ctgtaaatac cataactcat ctccttataa agcaaacgga
     7261 tacccagtaa aaatttactt ttcacaagat atccgcctct aaactatctc attttattgt
     7321 cttttaccgt gacagttttt aaatttctta ccagaaccac atgggcaaag ttcattgcgt
     7381 ccaatctggc tcaaatccaa atcttctggc atacttgctt ggtgagcagc gatattgcga
     7441 gtcgctgttg tactgatatg acgttctgcc tgtggtcttt cttgttcatg aatttgtgct
     7501 ttcatcatca agcgtgtcac atcaaactca atcgaaccaa tcatatcatt aaacatacgg
     7561 aaaccttctg cctgatactc aacaacaggg ttgttctgag catagccacg aagtccaacc
     7621 gcgttacgca attgatcaag ggcatcgata tgatctgtcc acttgttatc caccactcgt
     7681 agaatcaaaa ctttttggaa ttctttaact gcttcttcat cgcgtagttt tgaaacctga
     7741 ctatcgtaaa ccttcaaggc acgttggaaa agctcttcct tgatggcctt atcagacaag
     7801 cctgacaagt cttccatcgt aatagaatct tcaggaagca agttgtactt agcaaagttc
     7861 aaaattgcct ctagtttttc atcttgtttg gcacgcgcat gaccatcaac gacacgttca
     7921 agcgtgcgct taatcataga ctgaatttca ggtgccaagt cacggtctgc agtaatgaca
     7981 tcataacgtt gagtatagat aatctcacgt tgttcacgca tgacatcgtc gtattgaagg
     8041 acttgtttac gggtatcgta gttatttcct tcgacacgtt tctgagctgc ttcaacctga
     8101 cgcgtcaaca tgcgagactc aatcgcctct tcagacatgt tcaagcgttc aaagattccc
     8161 ttcaagcgtt cagaaccaaa acgtttcatc aaatcatctt caagagatag gtagaattgt
     8221 gactcacctg gatctccttg acgacctgaa cgtccacgaa gctggttatc gatacgacga
     8281 ctttcatgac gttctgtacc aataacacaa agtcctccaa gttcacgaac accttcacca
     8341 agcttgatgt cggtaccacg acccgccatg ttggttgcga tggtaacggc accacgttga
     8401 ccagcattca tgatgatttg ggcttctcta tagtggtttt tggcattcaa gacttcgtga
     8461 ggaacaccag ctgcaaccaa tttcttagaa atgtagtcac tagtttcaac cgctactgta
     8521 ccaaccaaga caggttgacc cttttggtaa cgagccttaa cgtcttcgac aaccgcttta
     8581 aacttagatt ctatacttgc ataaagaagg tctgagtggt caatacgttg aacaggacgg
     8641 tttgttggga ttggaataac acgaatgttg tagatttcac ggaattcttc ttcctcagtc
     8701 ttacctgtac ccgtcatacc agacaatttc ttgtacatac ggaaaaggtt ttggtacgtg
     8761 attgaggcag atgtcttggt ttcatcctgg attggcacac cttctttggc ttcaatagct
     8821 tggtgcaatc catcagaata acgacgacct tccatggtac gacctgtaaa ttggtcgaca
     8881 atcaagattt cttgctcttc gctcaccaca tagtcaatat cgagaagcat gatgtagttg
     8941 gcacgaaggg cgttatcgat aaagtgggtc aaagccacgt tttcgatgtc atagaggttt
     9001 tcaagtttga agtagctttc agccctgtca atccctgaat cagacaaacc aatagtctta
     9061 gactgcacat cgatgatgta gtcatctttg ttcaaagatt ttacatagtg gtctgccatg
     9121 tgatacaact gactggtttc aaccgcattg gcacctgata caatcaaagg tgtacgagcc
     9181 tcgtcaatca agatagagtc aacctcatcg accaaggcat agttaagcgg acgttgtacc
     9241 atgttttcag cgcgaacgac catattgtca cgaaggtagt caaatccgat ttctgagtta
     9301 gttgagtaag taatatcaca ctcataggct tcttttttct ccattggaga tttggtagcc
     9361 aagttaatcc ctactgacaa accaagccaa gagtacaatt cacccatctc agtcgcgtca
     9421 cgttctgaca ggtattcatt aaccgtaact acgtgaaccc ctttacctga aagggcattg
     9481 aggtataccg gcatggtcgc agtcaaggtt ttcccttccc ctgtacgcat ctctggcacg
     9541 tcaccatggt gaagaacaat cccccccatg acctgaacct tataagggaa gagacctagg
     9601 acacgtttgg caccttcacg gacaaccgca aatgcttcgt aaagcaatga atccagtgat
     9661 tctccatttt gataacgttc cttaaattca actgtttttg cttttagttg gtcgtcagtc
     9721 aaagcagcca tttggtcttc gtatttgaaa accttgtcag ccatcttttc cagacgacgg
     9781 atttctcctt tatcattttc gataattgtt tttaaaatat tagccatgtt tttccttact
     9841 ttaaattccg aatattttag aatgttcctt taattttagc acaattactg attattttca
     9901 aggaagaatc cccattttga aaaggaaaaa gaggttagtt tccaagctaa cctctctgac
     9961 ttttatgata ctttaattgc caagaatcgg caaaatagca aataggataa ataagttaat
    10021 ccaaagagaa agacagcaga tcaatccaaa aacaaagaga ctgactttct tggacagcaa
    10081 ggccatcaaa atggacagaa tgccaaaaac tagcaagact ttctgtatgc tgaagaggtc
    10141 aatcttcccc cccccagaat cggactgccc caaggaagaa agaagaaagc aatccagatc
    10201 aacagaacta aaccaatata gaccttagaa tagcgtgtaa taaatgattt tagatgtgcc
    10261 ataagccatc tcctaggatt gtatatcctt tacatttgta tatgtccatt ttcgacaact
    10321 aatacatctg tacaaaggtc tgaaatatct tccgatatgt gcgacgtcag gataaccaga
    10381 ccattttctt ttttcaggta agataaaatg acctgtttgg ttaacctcac acttttctca
    10441 tccaaagcat tcataggttc atcgagaaag agtatagaag gagaggaaat aaaggcttga
    10501 atcaaggcca ttttttgctt tgttcccaag gataaatgcc ggtattcaac gtcttcaaat
    10561 tcctgtaaat catagtattg aatccaatag gcaattcttt tttccgtaac tttagatgaa
    10621 aaatacctta acagttccaa attttctctc agggataaat gagataaaaa ctcgactttt
    10681 tcaattaaaa ttcctgcatc ctgaatataa tgatttttta tcccgtaaac tttaccatct
    10741 tgaagaactt ttcctttgtc aagcttaata taaccagcaa gtatctttaa aagaaccgtc
    10801 ttgccagatc cattatcacc tttaagtcca taaatttttc ctgattgaaa caccaaattc
    10861 aactgattta aaataggtct tttcccataa attttctgtc catttataat ttcaagtctc
    10921 atcgtttatc ctttcttaaa tttctcttcc aagcgactaa gaatcaacat aactaataag
    10981 cttaagagta ctaaatacac tgttacaata tgatccatca tccattcttg tcccacaaat
    11041 gccaaaaaat agagaaaaaa agaaaaacca gcgcccgcac taatcagtgc tatcagataa
    11101 gacagtagta agtacaacat cattaactga gcaagtaaaa agaaaagtgc gactgttttg
    11161 aaatgaattc ctagcggaag taaaccaaga aaccagacaa acaaatcttg agtaaaaaat
    11221 ttagaaatga caaccaatcg tttccttgta taatcgaaaa aggagcttga ttgatagcga
    11281 atcaagtgat ggtaatggtc tgccaaatca ctttcaagta aaatgacaga gagccatcct
    11341 accatgaaaa gcgaaaggtt taacaagagt ttggggattt ctaaattcgc ttcagaatag
    11401 tcattatagg aaaaaattga aatcaattct ctcttgaaaa agataacagc atcctgcttt
    11461 tgaaccgctg ttgacaatag atagtttatc aaaatcatca tcagaactat acgaagtagt
    11521 aaaacgatct ttctctttag ccaaatattg ttaaaattct taaacattat cttcatattt
    11581 tttaagtacc atataaggga caacataaag gatataagga gtaaagagtt tcatcaaact
    11641 tacatcccca tagctagctt gcatcaaact cgtcatagga accatatagt aaggcaaggc
    11701 actatagagc agcatagaac caagccaaag aaacatcaaa taggtgattg ccgaacgagt
    11761 cacattcccc acataatcaa ctatttgtaa aaaatagatt gcattgatga aaataccgat
    11821 tagtaggaca caagtaaaga acaaatagct ttttatctct ccatctagga gtctttgtaa
    11881 accactccca tcagaaaata gagaattcca ttcaagagga gaaaaagtcc caaagaaata
    11941 ggttataatt gcaattatca gcacagtcac taaatatatc aaacaaggga tacttgcaac
    12001 ttgcaaagtc aactttcttt ttaacccttg atagctcact tctcttccaa tactcaatcg
    12061 taaaacttta tttttcagct caatatattg aaaacctagc aaaacaatga tgattggaat
    12121 aataaatgat tgataaaaac ctagattgaa ctggagaata cgaaaatcta atgctgattt
    12181 taataagtca tttttaattg cttgtccatc gaatttagct agatcgggcg catgaatatc
    12241 aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag
    12301 caagacataa acaaatttat gccttgccaa agttaagaga ggaatcttca taagccacct
    12361 cctacaaata gaaagtaata taatactcaa tgaaaatcaa agagcaaact aggaaactag
    12421 ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa gtcagttaca
    12481 tatataatcc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat
    12541 gccttccgcc tttagacttc cctagttccc gtctcaagtc aagcattttt ttgaaacaga
    12601 tatagtctaa ccagtcacta gcaaaagcga taagtagtaa taatagccaa ataccccata
    12661 acttgatatc tgtcaaattt ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc
    12721 aagcaaggct aaaaagagca tagagggtga tgtaaatcca gtaaaaatag taaaaaattg
    12781 ggaaaatctt actatctctg tttgcctttt caatccagct gaaaaagtaa aaacagggca
    12841 ataagattat cattttaaac aagtattcca tcacaaacct cctcttttaa attgttttct
    12901 ttagtttcgt tctattaaat gttattacca atataaacct tggaatagcg tgtaataaat
    12961 gattttagag gtaccataag ccacctccta caaatagaaa ccgatataaa tcaatgcctt
    13021 ccacccttag acttccctag ttcctgtctc aagcgaaaca tttctttgaa acaggaataa
    13081 gttaaccaat tcataccaat agctagcaga ataaaaagaa accaaatgcc ccataacttg
    13141 atatctgtca catttctcaa gacggtattg aaaaacagaa ctgaaacaac tgtccaagca
    13201 aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa aataataaaa aattggaaaa
    13261 aacttactat ttctgttggc cttctcaatc cagttatcaa aataaaagta cggtgctaaa
    13321 agtaagaatt taaacaaatg ttccatcacc gacatcaccc tccttctttt gatagcgttt
    13381 tctattattt tattatatca aaaaaatccg gaactgtcat tccagattct acttttttat
    13441 ttgcgttttc ttgcgatgag atgaatcggt gttccctcaa aaacaaaggc cttgcggatt
    13501 tgattttcca agaaacgcag gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg
    13561 acaaaggttg gtggtttggt tgccacttgg gtcgcataga aaatcttgag acgttttcct
    13621 ttgtctgtcg gtgttgggtt gatggcaatg gcatccatga tgacatcgtt caagacagct
    13681 gatggaatac gtgtattttg actttcgctg atttgcttaa tcatctcagg aagtttgtgg
    13741 agacgttgct tagtcaaagc tgatacaaaa ataatcggtg cataaggcag gtattggaac
    13801 tgctcacgga tatcttcttc ccagtttttc atggtatggt tgtctttttc aagcgtatcc
    13861 cacttgttga ctacgataat cattccttta ccagcttcat gggcaaatcc tgcgatacgc
    13921 ttgtcgtact cacgaatgcc ttcttccgca ttgatgacca tcaagaccac atctgaacgg
    13981 tcaatagcac gcatggcacg cataacagag tatttctcag tattttcata aaccttacca
    14041 gacttacgca taccagccgt atcaatcatg gtaaactctt gaccatctgt atctgtaaag
    14101 tgggtatcaa tagcgtcacg agttgttcca gcaacaggac tggcaatgac acggtcttct
    14161 cccaagatag cattaatcaa gcttgatttt ccaacgttag gacgaccaat caagctaaac
    14221 ttaatgacat ctggattttc ttcttcatat tcatttggaa ggttttccac aatcgcatct
    14281 agtacatccc ctgtaccgat accatggaca gatgagatag gcagtggttc acccaaaccg
    14341 agagcataga aatcatagat atcatttctc atctcagggt tatccacctt gttgactgcg
    14401 aggataactg gtttgtgggt cttataaagc ttgcgggcta cgtattcgtc tgcatcggta
    14461 attccttcct taccggacac gacaaagacg ataacatctg cttcttccat ggcaatttct
    14521 gcctggtgct tgatttgttc catgaaagga gcatcgacat catcaattcc tcctgtatca
    14581 atcatgctaa aagaacgatt gagccactca cccgttgcat aaatacggtc acgtgtcact
    14641 ccttcgacat cttctacaat ggagattcgc tcaccagcga tccgattaaa tagggttgat
    14701 ttcccaacat tgggacgtcc tacaatggca atagttggta gggccataat ttctcacttt
    14761 ctacaataat ttcttctgtt caagattttt tctagttgag cttggttcag cttgaccaaa
    14821 ctgttctgct aggcgctgac tccagcttgt ggtcgcacgc cccccagcat agtcagcctg
    14881 cacacggtca taagcttgga ttgtctcagt tgactgttct tggtattctt cctcaaagac
    14941 aacattctct agtggcagtc tcggtttcac atcatgatgt tgatttggca cacccagtgc
    15001 catcccaaag acagaatagg tgtagtcagg taggttaaag agctctgcca cttcttcaga
    15061 cttgtatcga accaaaccga taatcacacc accatagccc aagctttcag ctgccaacaa
    15121 ggcgttttgt ccagcaagag ctgcatcgac cgaactaatc aagagacctt ccacaccttg
    15181 gggttggaag gtgtcggtat gaagtcgggc tcccttttct gctcggttca aatctccgac
    15241 aaagagaagg aaaacagcag actggcgaat ggcttcttga ggtaccaatt catacaaggc
    15301 atctttcttc tcttgacttc gtaccacaat cacagagtag gattggaaat tcttccaaga
    15361 tgatgccatc tgggctgctg tcaaaatctc atttaagtct acttggggaa tttcttgctc
    15421 tttaaacctg cgcactgaag tatgagcctt catcaattta atggtttctg tcatcgacgg
    15481 tttactcctt ctaaacgagt ctcctcagcc aaataacgga tgcgttccat gacccgtctg
    15541 gcttcccagg tttcgtcatt tccatgtttc actttcgcaa aatgcttctc caaatcttca
    15601 aagttgaagt tggatgtgaa aaaggtcggt aaattttcct gcatccgata ttggagaatg
    15661 acctgcagga tttcgtcacg tacccaaacg gttgattgct cggcgccaat atcatctaaa
    15721 atcaggacct cagacagctt aatctcatcc accaaggtct taacattgcc atcactgata
    15781 gcatttttga catcaatgac aaagctagga tagtggagga gagttgatga aacaccacgt
    15841 ttttctgata aatcatgagc taaggccgcc accatgaaac ttttacccac accaaagtct
    15901 ccatataagt aaagaccttt tcgaatagct ggatattgct ccacgaaggc tagtagcttt
    15961 tcaaaaactg gtaagcgccc caaatcatcc aagtcaactt gagccaaact agctttcttg
    16021 agactggctg gtagattgat taacttgaga cggttcttaa tagccgcttc tttttcagcc
    16081 gcgattagct caggagtttc ttcatatgaa acatctgcat agccatgatt cttaaccaaa
    16141 atcggcttgt agcctttggc aatataatcc gtatccccac ggagaaactt gtcacgctcg
    16201 gtgatgtact gattaaactt ggagatactg cgatttaatt cctctggagt caaggattct
    16261 tgctggataa aagccgcaac atcagggtcc ttcatgattt tctggaccaa atcttgataa
    16321 taaaaacggc tgggttgacg tttgagtacg tctccgacac tttccatcta atctcctcct
    16381 ttttctaatc gagctaatag ttcttgcttc ttacgttcta gttccagacg agtttcctcg
    16441 ctggtttcat tcttatattc aggattactc catttaggaa cattggtttt tactggggca
    16501 gtctgattct gtttttgtgt ttttgctttc tgtcctcgct cacggatgcg caagactgcc
    16561 ttttctgccg aatgaatctt ttgataggca tagtcattgg ctaccttcat ggcatatttc
    16621 tcattgatat ttgccgaatc gaccttatta aaggtcaata aaagaatgat attgatgact
    16681 tcgtccagca agcccaagcc agccatctgt tgcaagagtt ctctttctgt ttgggtaatg
    16741 gttcccttgc gtgtttgctt gatttctgcc aagaactgca gggcagtttt acttttggct
    16801 tctttgataa tggttgtttc cttaagacta aagtcagagg aaactggttt ttgagcaatt
    16861 ttttcacgca tgcgtttggt tgaaataacc tgagaaacag ctgttgactt ggccaattga
    16921 taggtttcaa accaagtcca tttcttctcc tcggcaatag caaagaggtt taagacatcg
    16981 gactgctcat ccgcaaaacg aagtccatct cgagccatca gctggcgaaa atgttccaag
    17041 tcaaaatcat tggccacttt cttcttgaga ccaaggtctt cttgactgcc tagttctgcc
    17101 aattctggaa agacttgatt gagtgagaca ggtatttctt caccatcagc actttcaact
    17161 ttcaaatcct ccacagcaga gtcgccaatc tttttctcta agagtctgcg ataaacagga
    17221 tgctccaaga agtcttgact agatagagga gcatggaggg ctagctgata aacatccccc
    17281 ttttgataga gggtcaagag attaaaagca gataagattt tcaatgattt tatcagtcta
    17341 tccatcccaa agttgagatg attgaggata cttgaaaaaa gatattcctt tctaccatta
    17401 tcccaaaaac tgattgtata aagataaagg ctcagtgcct cctgaccgat aatcgggagg
    17461 tagcactgta ccagagatga ggtatcttgc gacacccgat tattctttag ataagaaaaa
    17521 cggtcaattg gcttcattta tctttccttt ttctttttag aggactgggt gatttgttgg
    17581 agcaagctct ctaactcact gacatcctta aaactacgat agacactagc aaaacgtaca
    17641 taggtaatct cgtccaattc agccaactcc tccatgacga gtgaaccaat gtcctcactt
    17701 tgaatttcat tttcatttcg accacggagt ttctgttcga tacgattgac taccatgttg
    17761 atttcatcac ttgacacagg acgtttctgg gctgagcgga taatcccatt aaagatttta
    17821 tctctggaga attgttcccg tgtaccatct tttttaacaa ccactaaggt tctttcttct
    17881 actcgttcgt aggttgtaaa acggtgttgg cattcgtcgc actcacgtct tctacgaatg
    17941 gtgttccctt cttctgcttg gcgactatcg ataacacttg acttggtagc cccacatttt
    18001 ggacaacgca tcctttccct ccttatcgtt ttcttttcat tataccattt tttaagcgat
    18061 tcccaaaaca attcttcttt ttgcttgaca agttttttgt tttgttgtat tatttaatta
    18121 agacaaaagg ataagagaaa ggagactaag atgtcctgga catttgacaa caaaaaaccc
    18181 atctatttac agattatgga gaaaatcaag cttcagattg tttcccatac actggaaccc
    18241 aatcaacaac ttccaaccgt gagggagcta gctagcgagg ctggtgtcaa tcccaatacc
    18301 atccaaagag ccttatcaga ccttgaacga gaaggatttg tctacagcaa gcgaacaact
    18361 ggacgatttg tgactaagga taaggagcta atcgcccagt cacgcaaaca attatcagaa
    18421 gaagaattgg aacacttcgt ttcctccatg acccattttg gctatgaaaa agaagaacta
    18481 ccaggcgtag tcagtgatta tattaaagga gtttaagcct atgtcattac tagtatttga
    18541 aaatgtatcc aaatcatatg gagcaacacc agcccttgaa aatgtttctc ttgacattcc
    18601 agctggaaaa attgtcggcc ttcttgggcc aaacggctca ggaaaaacaa ccctgattaa
    18661 actaattaat ggcctcttac aaccagatca aggacgtgtc ctcatcaacg acatggaccc
    18721 aagcccagca accaaggccg ttgtagctta tttgcctgat acgacctatc tcaatgagca
    18781 aatgaaggtc aaagaagccc taacctactt caagaccttc tataaagatt tcaatcttga
    18841 acgcgcccat catctacttg cagacctggg cattgatgaa aatagtcgtc tcaagaaact
    18901 atcaaaagga aacaaagaaa aggttcaact gattttggtt atgagccgtg atgctcgtct
    18961 ctatgttttg gacgaaccca ttggtggggt ggatccagca gcccgtgctt atatcctcaa
    19021 taccattatc aacaactact caccaacttc taccgttttg atttctaccc acttgatttc
    19081 tgatatcgag ccaatcttgg atgaaattgt cttcctaaaa gacggaaaag tcgtccgtca
    19141 aggaaatgta gatgatattc gctacgagtc aggtgaatcc attgaccaac tcttccgtca
    19201 ggaatttaag gcctaagcaa aggagattat ttatgttttg gaatttagtt cgctacgaat
    19261 ttaaaaatgt taacaagtgg tatttagccc tctacgcagc cgtgctagtc ctttctgccc
    19321 tcatcggaat acagacacaa ggctttaaaa atctacctta ccaagaaagt caggctacta
    19381 tgctactttt tctagctaca gtctttggtg gcttgatgct tacacttggg atttcaacca
    19441 ttttcttgat tattaaacgc ttcaaaggta gtgtctacga ccgacaaggc tatctgactt
    19501 tgaccttgcc agtttctgaa caccatatca tcacagccaa actaatcggt gcctttatct
    19561 ggtcattgat tagcaccgct gtattggctc taagtgctgt tattattctg gctttaacag
    19621 ctccagaatg gattcctctt tcttatgtga ttacatttgt agaaacacat cttcctcaga
    19681 tctttcttac aggtatatcc ttcctactaa atactatttc aggaatcctc tgcatctacc
    19741 tggctatttc cattggacag cttttcaatg aataccgtac agcactcgct gttgcagtct
    19801 acattggtat ccaaatcgtc attggattta ttgaactttt cttcaatctt agttctaatt
    19861 tctatgtcaa ttcactggta ggactcaatg accatttcta tatgggagca ggtatagcca
    19921 ttgttgaaga actcatattc atagctatct tttatctcgg aacctactac atcttgagaa
    19981 ataaggttaa tttgctttaa ataattttta cctagatatg taacatactc atagaacaaa
    20041 agagaccagg caaaaagtct ttacaattag aaaacgcata gtatcaagtg ttaaaaatcc
    20101 ttgatattat gcgttttttg tgagctgact tatttccttt cactatatcg caaaatgaaa
    20161 taagaacgga acgatgggat tttggaattc aaatcaattt ataagaatgt tttagaagta
    20221 atattatcct attccagatt cagttcacta tacaattgag ttttcaagca acctgtttac
    20281 ataatgtgta cataattagg ttcgtgattc cacccttttc acctttaaaa acctcgcttt
    20341 cgcaaggctc ttctatttat aagataaggc acgtttaaag gttttccaaa tccctaaatc
    20401 atccgtttga agaacgagac tagcatacat gcgtccgata aatcctgttg ctaccaccgc
    20461 aaaaatcact gtaatagcaa gtgaaatcca tgcttccgct ccctccgcat agccattaat
    20521 cgttcgaaac ggcataaaga aggtcgaaat aaagggaata taagaaccaa tcttcaagag
    20581 gagattgtca ccagctgcac ctagagctgt cactccaaaa aaaccaccca taatcaaaat
    20641 catcaaaggc gacaaggctt tccctgagtc ttcaggacga gaaaccatag atcctaggaa
    20701 ggctgccaag actacgtaca tgaaaagact gatcaaaata aagagcaagg tattcagtga
    20761 gatagcatct cccaagtgat ccaaaatacc agactgagcc aagaatggca aatctttaaa
    20821 gagcaaaacg gcagccagac cacctacaac atagatccca atatgcgtta aaatcactag
    20881 aaacagagcc atcatccgcg catagaaata gtgacttgcc cttatgctag aaaagacgac
    20941 ttccataatt ttggtgcctt tttcactggc aacttcctga gctgttacac ccgcataggt
    21001 aatcagaatc atataaagaa agaatcctaa ggcacctgct gcaattgttt gaataaactt
    21061 tttattttcc ttggcttcat caatcttttc tgtgaattga attgtctgcg ctaagcgttt
    21121 ttcctgctct tgagacaagg aagcagttga acgattaagc tgattttgca gttcattgag
    21181 tgtacctgta acctcaaatt taattccatt ttcaagcgat gtttcgccat gataaactgc
    21241 ctttagaaca ctatcttctt gatcaatggt caaataacct tttaattttt cttctttaat
    21301 tgcttctttg gcacttgctt cgtctttata gtcgaagtta acaccattta cattcttcag
    21361 tccttctgct acagatggca ctgttgtcac tactgccact ttattatttt tagccataga
    21421 agaaccttgg agatgcccaa ttcctacaga gattcctaaa aagaggaacg gcgaaatcac
    21481 cataaagaag aaactccatg actcgacatg tcgaagatag gtttccttga ttacaaccca
    21541 catatttctc atacttccac tcctgattct agtttaaaga tttcatcgat agttggcgct
    21601 tgttggtcaa atgttgcgat atattgacct tgagtcaaga ttgggaagag ttcccttcca
    21661 gcgctctcat cctccaaaat caatttccaa ctgccttgtt tggtcaagct cacctgtttg
    21721 acatgaggaa gattttccaa ttcttccttg cttcgttcac ttgaaacaaa gagacgcgtt
    21781 ttcccgtatt gattgcggac atcctgaact ggtccgtgca agaccacacg gccatctcga
    21841 atcatcagaa tatcgtcaca aagttcctca acattggtca tgacatggtc agaaaagata
    21901 atggttgctc cgcgctcttt ttcctgaaaa atgacttgtt tgagcaattc tgtattaact
    21961 gggtccaatc cactaaaagg ctcatccaag ataatcaggt ctggttcatg aatcagagta
    22021 ataatgagct gaatcttctg ctgatttcct tttgacagac tcttgatttt atctgtcagc
    22081 tttcctttta cttccaacct cttcatccat tgagggagtt tttctttgac ttctttggca
    22141 tccatgcctt ttagagtcgc caagtagcga acttgttcaa gaactgtcaa tttaggcatg
    22201 agactgcgtt cttcaggcag ataaccaatc cgagcataga tctcctgacg aatatcctga
    22261 ccatccagac cgatttctcc ctgatattct aggaatttta aaatactatg gaaaatcgtt
    22321 gtttttccag caccattttt tccgactagt cccaaaatac gacctggtcg cgcttgaaag
    22381 tcaataccaa acaaaacttg cttggatcca aaacttttct ctagacttct tacttctagc
    22441 atctttcacc tccgaaattt cttgcactca ttatactcct ttttgatagc ctttacaatg
    22501 ttttttgtcc atttttagaa gactattgct gtgtaaaata tggcctggag cacttttata
    22561 ctcaatgaaa atcaaagagc aaactaggaa gccagccgta gactgctcaa agtacagctt
    22621 tgaggttgca gata
//
LOCUS       DAVBOM010000033        22095 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBOM010000033 DAVBOM010000000
VERSION     DAVBOM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.033"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(1..245)
                     /locus_tag="VQ878_001376"
                     /pseudo
     CDS             complement(1..245)
                     /locus_tag="VQ878_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ878_001377"
     CDS             complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ878_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3095709.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2701..3570)
                     /locus_tag="VQ878_001378"
     CDS             complement(2701..3570)
                     /locus_tag="VQ878_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3095710.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3793..4473)
                     /locus_tag="VQ878_001379"
     CDS             complement(3793..4473)
                     /locus_tag="VQ878_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3095711.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4431..5537)
                     /locus_tag="VQ878_001380"
     CDS             complement(4431..5537)
                     /locus_tag="VQ878_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET3095712.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWVRSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELILENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5473..5670)
                     /locus_tag="VQ878_001381"
     CDS             complement(5473..5670)
                     /locus_tag="VQ878_001381"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095713.1"
                     /translation="MKITYHVKDNQLEVETDKYTYTAARNGSKEVGIQESDIAATLSA
                     DEYNSNRQTFEREYKYKSKCP"
     gene            complement(5648..5902)
                     /locus_tag="VQ878_001382"
     CDS             complement(5648..5902)
                     /locus_tag="VQ878_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095714.1"
                     /translation="MLNVDQDFMSISKPNKSGSDWKKTFTVRTTNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6260..6793)
                     /locus_tag="VQ878_001383"
     CDS             complement(6260..6793)
                     /locus_tag="VQ878_001383"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3095715.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6780..6995)
                     /locus_tag="VQ878_001384"
     CDS             complement(6780..6995)
                     /locus_tag="VQ878_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3095716.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(6962..7105)
                     /locus_tag="VQ878_001385"
     CDS             complement(6962..7105)
                     /locus_tag="VQ878_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET3095717.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7339..9057
                     /locus_tag="VQ878_001386"
     CDS             7339..9057
                     /locus_tag="VQ878_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET3095718.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9168..9515
                     /locus_tag="VQ878_001387"
     CDS             9168..9515
                     /locus_tag="VQ878_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3095719.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9793..10629)
                     /locus_tag="VQ878_001388"
     CDS             complement(9793..10629)
                     /locus_tag="VQ878_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3095720.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10642..11271)
                     /locus_tag="VQ878_001389"
     CDS             complement(10642..11271)
                     /locus_tag="VQ878_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3095721.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11281..11922)
                     /locus_tag="VQ878_001390"
     CDS             complement(11281..11922)
                     /locus_tag="VQ878_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3095722.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12068..13297)
                     /locus_tag="VQ878_001391"
     CDS             complement(12068..13297)
                     /locus_tag="VQ878_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET3095723.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13287..14453)
                     /locus_tag="VQ878_001392"
     CDS             complement(13287..14453)
                     /locus_tag="VQ878_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3095724.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14597..15610
                     /locus_tag="VQ878_001393"
     CDS             14597..15610
                     /locus_tag="VQ878_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET3095725.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPNQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15655..16074)
                     /locus_tag="VQ878_001394"
     CDS             complement(15655..16074)
                     /locus_tag="VQ878_001394"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET3095726.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ878_001395"
     CDS             complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ878_001395"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET3095727.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17577..18455)
                     /locus_tag="VQ878_001396"
     CDS             complement(17577..18455)
                     /locus_tag="VQ878_001396"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET3095728.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18471..19976)
                     /locus_tag="VQ878_001397"
     CDS             complement(18471..19976)
                     /locus_tag="VQ878_001397"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET3095729.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19991..20527)
                     /locus_tag="VQ878_001398"
     CDS             complement(19991..20527)
                     /locus_tag="VQ878_001398"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET3095730.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ878_001399"
     CDS             complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ878_001399"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET3095731.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ878_001400"
     CDS             complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ878_001400"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET3095732.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21786..21986)
                     /locus_tag="VQ878_001401"
     CDS             complement(21786..21986)
                     /locus_tag="VQ878_001401"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET3095733.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6571 a         4737 c         4032 g         6755 t
ORIGIN      
        1 gtcatatatg catggttacg accaccacgt gtttcttgaa ggagagagtc gagtccgaac
       61 tcctcatatt tttttacgtt tcgccaaatc gttgtttgat tacagtctaa aagctctata
      121 atctcttaat aagatttgcc catcagacga aatagaacga tttgaaggcg tttatgatat
      181 ttagctgtac gagagtcttt taaaagtgtt ttgatggttt tgatttcttc tttagttgat
      241 ttcatattac tattgtataa tgctttttga tttgagtcta gtattatact cttcgaaaat
      301 ctcttcaaac cgcgtcagct tcgccttgtc gtatagatgt tactgacttc gtcagttcta
      361 tctacaacct aaaaacagtg ttttgaacag tctgcagcta actttctata acaaaatgaa
      421 ataagaacaa gacaaatcaa tcaagacaat caaatcgatt tctaacaatg ttttagaagt
      481 agatgtgtac tattctagtt tcaatatatt atagtttgct ctttgatttt cattgagtat
      541 tagttcaata tctaaaaaaa gaaccttgcc aagcaagatt cttttagtgt ctaacttaaa
      601 taattgttct tctgggaact aaatcgaatt aagcttcgat ttctgtaacc atacctgaac
      661 caacagtacg tccaccctca cggatagaga atgtagtacc ttgttctacg gcgattgggt
      721 gaatcaactc aacgtcgatt gtcacgttat caccaggcat taccatttca gtacctgctg
      781 gaagttcgat tgaacctgta acgtcagtag tacggaagta gaattgtgga cggtagttgt
      841 tgaagaatgg agtgtgacgt ccaccttctt ctttagtaag gatgtagact tcacctttga
      901 atttagtgtg tgggttgatt gaacctggtt tagcgataac ttgtccacgt tcgatttcat
      961 cacgttgaac accacgaaga aggacaccta cgttatctcc agcaagacct tcgtcaagtt
     1021 gtttacggaa catttcaaca ccagtaacaa ctgctttttg agtttcttct ttgataccaa
     1081 cgatttcgat ttcgtcgttg actttaacga taccacggtc gatacgtcct gaagcaactg
     1141 taccacgtcc agtaattgag aatacgtcct cgactggaag aagcaatggt ttgtcagtgt
     1201 cacgttctgg ttctgggata tactcatcaa ctgtgttcat caattccata acgatgtctt
     1261 cgtatttaga gtcaccttca agagctttaa gtgctgaacc ttggataact ggaagatcgt
     1321 cacctgggaa gtcgtattct gacaataggt cacggatttc catttcaacc aattcaagca
     1381 attcttcgtc gtcaaccaag tcaactttgt tcatgaagac gataaggtgt ttaacaccaa
     1441 cctgacgtga aagaaggatg tgctcacgag tttgtggcat tggtccgtca gttgaagcta
     1501 ctacaaggat agctccgtcc atttgagcag caccagtgat catattttta acgtagtccg
     1561 cgtgtcctgg agcgtcgatg tgagcgtagt gacgtttttc agtttcgtac tcaacgtgcg
     1621 cagtgttgat agtgataccg cgttcgcgtt cttctggagc agcatcgata gacgcatagt
     1681 ctttaggttg gttaactgat gaaggcaagc gacgtgccaa aacagttgtg atagctgcag
     1741 ttagggtagt tttaccgtgg tcaacgtgtc cgatagtacc aatgttaacg tgtggtttac
     1801 tacgatcgta tttttctttt gccatttgag taaaagcctc caataaaata tattttatag
     1861 atagacagta ggcaatacag tctaactttc cttactattt tatcaaattt cagctaaatt
     1921 gcaagtgttt tacaacgttt ttgtgaatta ttcttggtaa aaatttaact aactaataga
     1981 aagtactaaa tagacttatc cttcaaggag ttttcagcat tatccatcca ctcacttgct
     2041 gaaaatgtaa acagtctctg gtttatatag taaaatgaaa caagaatagg gcaaatcgat
     2101 caggacaatc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact attctagttt
     2161 caatctacta tacaacctca aaactgtgtt ttgaacaacc tgcggctagc ttcttagttt
     2221 gccctttgat tttcattgag tataaaattg cagataaaac gataacaatc ataggactca
     2281 gcagagtcaa tgtaggtcga agaatagccc ccctaatcgc ttattttata gcaaaatgaa
     2341 atagaaactg aacattttgt tgaggaaggt aaatcaattc ctcacaatgt ttgagaaaga
     2401 agggaggact attccaactt caacccacta ttaatatata atagaatgaa aactgcacaa
     2461 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     2521 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     2581 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     2641 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     2701 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     2761 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     2821 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcgggtcc
     2881 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     2941 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     3001 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     3061 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     3121 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     3181 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     3241 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     3301 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     3361 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     3421 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     3481 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     3541 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     3601 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     3661 aaaataggat tcatagtttc ctagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     3721 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct tgttcctaga
     3781 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     3841 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     3901 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     3961 ttcagttttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     4021 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     4081 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     4141 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     4201 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     4261 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     4321 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     4381 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     4441 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     4501 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     4561 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     4621 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     4681 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     4741 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     4801 aaacttgcag aatttgtatc tgcttcttta aaagtataat attttccgtc agtagtagtc
     4861 atgctactga gttttttatc tgtgacattg tagctggtac caatcagttg ttttttattg
     4921 gtaatgtagg ttccgtcact ttctttttct ccaattccag tatcattttt caatgatagc
     4981 aaacgccctt gttcatcaac atagcgaact ttcacatttt ctaagattag ttctgccaat
     5041 tctgaggttt ttttcttttt cttgatttct tcggttattt tccctttctc ttcttcggga
     5101 atatttagtt ttggaatgat tttttcaaca acggttcgtg atggttccac agtatcttgg
     5161 atgactgaaa agtcagctag aattgggaga ttatactgaa cacggtgact ttgagtgttt
     5221 actcctactc tttcattatt ctctgaaaat acttgtacgg tataagaaac aacatctttt
     5281 cctaatagaa catccccagt agagaaatag ccgccttttc ctagtttgct atctccagag
     5341 cccacttctt tcctaatctt atcagatagt tttttaccag tcagtacatt cgttcgcaca
     5401 atccctttgt ctacccctac aaagtgggag aactttttga actcttcaga accagatcta
     5461 acccaaccat tattaagggc atttgctttt gtatttgtat tctctctcaa aagtttggcg
     5521 attagaatta tattcatcgg cacttagagt tgctgctata tctgactctt gaataccaac
     5581 ttccttacta ccatttctag cggcagtata tgtgtattta tctgtttcta cttctagctg
     5641 attatcctta acatgatagg taattttcac ctggtataag agtcttcagt agtttatata
     5701 ctctgtcatc atctttagct ttagaagcag ctgagtttag ccaagttggg gtattaggag
     5761 tatctttatc aacctgtttc aagacattat tcaagtcatt tgctagccta ttggttgtcc
     5821 tcactgtgaa agttttcttc cagtctgaac cacttttatt aggcttagat atgctcatga
     5881 aatcctggtc aacattcaac acaatatcgc cttgtttttt agcatcttcc gttgcttctg
     5941 cttcaaattg atcatggagt ttttgttgct ctggtgtata gtttttttat ttacacgatt
     6001 taatgtacta ttttttattt tagtattaag aactccatta atacgatttt taaattctgc
     6061 ttcaaaaaat cccttaattt gttggtgcgc aagttcaaca ttcaaacctt tcttatacaa
     6121 gtcttcattc tgatacaagt cttcattctg aacgatttcg gctacacggt gaatggtttg
     6181 attgtatacc gtcttctctt aaccagcagt atccttagtt ttaatgacta ctcgataggt
     6241 tcctttagaa ccgttatagt catctagttt taaaaaagca ttccaaacat tcaaaaatag
     6301 ttggaacttc ccttaataaa tccgtcactt tctttttcaa gatagcccaa gcttgctcaa
     6361 taggattcaa atccggtgaa taaggtggta gaggtaagaa aaagtgttta tcttggatgc
     6421 agagttcatc caaaatgttc ttgggatgaa aactagcatt gcccatgaca ataacatgag
     6481 gtgtcttcaa agcaggtagg agttgcgttt tgaaccactc cacaaagaaa tcgcttgtca
     6541 tgcttttctt gtaaatcatg ggagctataa actctccgtc tacttgtcct gcaacaattg
     6601 aagttcgctc aaaacgacgt ccgctaatct tttcatagac tttctcccct ctaggagccc
     6661 gtgcataagg acgatagagg tagcggtcga ttcctgtttc atcaatatat acgattggta
     6721 aatcttttag gttatccaaa atatcaagaa actcagcgac tttctctggc tcttgttcct
     6781 taaagctcgt catctttttt taaagtgacc ttaatatact ttaaagctgc ccatacggag
     6841 ggcagagcac aatcaaaatg tgccgcaatt tcccgtaaaa aagcatctgg atgagcctct
     6901 acaaaggctt tcaattcctc taaaggaatc tttcggtttt tgacgactcg ctttttcctc
     6961 tctatgtgtc cttgttcaca tctttctttt cccacgtgaa gagagttctg acgccaacac
     7021 caaaaaactt ggctgcctcg acatggctgt gcccctcttt gatggaatct aatgctcgct
     7081 gtttaaaatc agtactatat gccatagctt tattataata tgcttgttta aaactaagca
     7141 actatatcaa tgttttgtta ttagaagact tacttttttt actgaaatcg aatttttcct
     7201 aacctcaaca tcatataacc ccaaaattca atctgacctg gtttgaagag atgttcgaag
     7261 cagataaggt tttactaaaa ctaaaaaaaa tgatataatc aaactgatta aatgttttaa
     7321 aaataaagga gaatttgaat gtcttaccaa gaaaattacc agaaatgggt tgattttgtg
     7381 gagcttcctg actaccttcg tcaagatttg gaaaatatgg acgaaaaaac taaggaagat
     7441 gccttctata caaatcttga atttggtact gcaggtatgc gtggcttggt tggtgctggt
     7501 acaaaccgta tcaacatcta cgttgttcgc caagctactg aaggattggc tcgtttgatt
     7561 gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac
     7621 ttctcacctg agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg catcaaatct
     7681 tacgtatttg aaagccttcg tccaactcca gaactatcat ttgcagttcg tcatctcaac
     7741 tgtttcgcag gtatcatggt cacagccagc cacaaccctg ctccatttaa cggttacaag
     7801 gtttacggtg aagacggtgg acaaatgcct ccacacgatg cggacgcttt gactacttat
     7861 atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac tgaaaaagct
     7921 tctggcttga ttgaagttat cggcgaagct gttgacgtag aataccttaa agaggttaag
     7981 gacgtaaaca tcaacccagc cttgattgaa gaatttggta aagacatgaa gattgtctac
     8041 acaccacttc atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt
     8101 gactctgttc aagttgttga agcgcaagca actgctgacc cagacttctc aactgtaaca
     8161 tctccaaacc cagaaagcca agcagccttt gcccttgctg aagaacttgg tcgtcaagtt
     8221 ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt tgaagttctt
     8281 caaaaagatg gtagctacct caacctttca ggtaaccaaa tcggtgctat catggctaaa
     8341 tacatcttgg aagctcacaa aaacgctgga actcttcctg aaaatgccgc tctctgcaaa
     8401 tctatcgttt caactgactt ggtaacgaag attgctgaaa gctacggcgc aactatgttc
     8461 aacgtcttga caggtttcaa atttatcgct gaaaaaatcc aagaattcga agaaaaacac
     8521 aaccacactt acatgatggg atttgaagaa agcttcggtt acttgattaa accatttgta
     8581 cgtgataaag atgccatcca agccgttctt gtcgttgctg aacttgctgc ctactaccgt
     8641 tctcgtggtt tgacacttgc tgacggtatc gaagaaatct ataaagaata tggctactac
     8701 gcagaaaaaa caatctctgt tactctttca ggtgtcgatg gtgctgaaca aatcaaagcg
     8761 attatggcta aattccgcaa caatgctcca acagaatgga acgcaacagc tatcactgtc
     8821 gtagaagact tcaaggcaca aactgctact gttgctgacg gtactgttac aaacttgaca
     8881 actcctccaa gtgatgtgtt gaaatacaca cttgctgacg gttcatggat tgccgttcgc
     8941 ccttcaggta cagaaccaaa aatcaagttc tacattgcag ttgtagggga aaccaacgaa
     9001 gaatcacaag ctaagattgc taacatcgaa gcagaaatca atgcatttgt aaaataaaga
     9061 cctataaaag atgagaccaa ccaacctcat cttttttcgt atcaaatcta agcaatttta
     9121 gaaactttat ggcatactag acttatcaat gaaagcgagg taatctcatg gaacaatttt
     9181 tagataacat caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata
     9241 aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg cccttactgc cgtaaatttt
     9301 caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca catttacttc atcaatagtg
     9361 aagaaccaag ccaactcaat gatttgcaag cattccgctc acgctatgga atcccaactg
     9421 taccaggttt tgttcatatt acagatggac aaatcaacgt ccgttgcgac tcttcaatgt
     9481 cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat
     9541 cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa
     9601 aacagttaca tcagcatttc attacagaac attttaattt tggaagtcaa atcaattttt
     9661 aacaatgttt tagaaatcac agtgggctat tccatattca attatccaga ttcaatcgct
     9721 attatcgttt tcctagatta caaaaaaact acgttttgct aatcaaaacg cagtttcagc
     9781 cactatttta tcttactgtc cttcttttac ttctttggtt gctacatctt ctccaaacca
     9841 tttttgactg atttcttgga acttgccgtc cttgtaaaga ctagaaaaag cttcatttat
     9901 cttcttaacc aagtttgtat cttccttacg ggctccaacc gcaaaagctt ctgtttctag
     9961 tccaactgta aagacattat aatcgtttaa aacaccttct gcttctaaat aataatttgc
    10021 atagacacgg tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa tcaaggcttc
    10081 attaaaggtt tggtattgat tcgcttcctt attagcgaca atattcttca aaatttctgg
    10141 atttgcttca aagtccgcat aaccagatga accagcttga gctcctaatg tctttccagt
    10201 catatccttt gcagtcgtga taccagatga tttcttcgta accaatacct gctcattctt
    10261 catatatgag ttactgaaag ccaccttttc acggcgttcg tctgtagcgg aatagccatt
    10321 ccaaatcaga tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc aatcaatcgg
    10381 ttgccaattt accgtgattc cgtatttttc aaaaacagct gtagctaaat caatatcaaa
    10441 tcctgcataa gaaccatctt tctgagcaaa tcccattgga acaaaagtac tatcaaatcc
    10501 aatagtaata gacttgttag actggtactt tgaccaatta tctccactag tttcgctaga
    10561 atttttccca caagctacta agaacaaagc agtcatcaga ctgactaata caagcatcca
    10621 ttttttcatc catttttcct cctatttagg ttctactttc aataatacat ctgcgatatt
    10681 ttcagcaaac tgcaaatcat gggtaaccac aatctgggtc atcccaagtt ccctattttg
    10741 caagattagc ttctccactt ccaaacgtaa ttctggatcc agggcagaag ttggttcatc
    10801 gtagccaatg atttctgggt caatcatcat agcacgcgcc aaagccaccc gctgcttttg
    10861 cccaccagat agtgagaaag gataggcctc tgcgtgtcct cctagtccta actgttccaa
    10921 gagtccactc gccttcttct cagcctcttc ctgcttcatt cccatggtct tcacaggcga
    10981 taaagtcaaa ttttccagaa ctgatagatg aggaaatagt tgaaaatctt ggaagacaaa
    11041 tcccagtagg ttgcgcttct gcaattcatc tagctctaaa ggttgtccat tataaaagat
    11101 ttgccctgaa tcaatggttt caagacctgc aagcatacgt aaaagagttg tcttacctcc
    11161 accagaaggt ccaacgatag ccaggatttg cttttcagga atacttagac tgaaatcaga
    11221 caggatttgt ttgtctccaa agactttatt gatatttcgt aattctaaca tagctgcccc
    11281 ctatctataa taactgtact ttttctcaac ttttttggaa ataattgtca caatcccaat
    11341 taaaatcaag taaatggctc ctgccaagaa cataggaacc agactagcat cgcggttagc
    11401 agctgttcga ctagccaaga taaggtctga aattccgaga gcatagacca aagaagtatc
    11461 cttgaccaaa ctcataactt cattaaagac actaggaaga acgatcttgg tcacttgggg
    11521 caagataata tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg cagcctcata
    11581 ctgtcctctt ggaatagtgt caattccccc acggaaaatt tctgcaaagt aagctgcata
    11641 gttgagaaca aaggcaataa tagctgcagg aaggcgatct aaacgaatcc caatacttgg
    11701 gagcacataa tagataaaaa tcagttgcaa gagtaagggg gttcctcgca taacccagat
    11761 gtaaatgtta atcagataat ggaggggctt ccaatggact tgcaaggcaa aggcaatcaa
    11821 aacgcccaag ggaatcgaaa atagcaagac cagtgcaaag acctgtacag tcgtgctcgc
    11881 accattcagt aaactcggta atatctcaaa taaataagac atactgcacc tcctaaaagt
    11941 aattgttcct attatagcat gaataaacaa gattaccaag tatttttgta aaaagattct
    12001 accatataca aataaaaacc gtagctatca aaagagataa actacagttc tatatgttta
    12061 aacattctta caatctctca aacagttctt gcatttgcac atcatctgga accagtttta
    12121 agtaagtgtg agcatggact tttgcttctt caaaatgtcc caattcacgc aagagataga
    12181 tatagtgttc cagaaattct ggattgtcct tcaaatctcc tgtcaactct tgataatgct
    12241 cataagcagt atccaaatcg tccatttctt gataagaacg agcaatcatc cacttggtca
    12301 aaagattttc tggctcctca ctctgcaagt ctagaatatc ctcataacgc tcctgctcca
    12361 gataaatagt ggctaaacga agcaagattt cttctgtatc ctcagcgtct tcttttgcag
    12421 taaggagata attttctgca ccactagcat catgcaattc ataagaaaat tgtgaagcag
    12481 ctagcaagag gcgagtttca aagggatttt tctctaatcc ttgcttagcg atacgcaggg
    12541 cttcttgaac ttgatgttcc ttatgtaaag cctgactgta cccatactca tagccttcaa
    12601 agtcaggaga aatggtatca agctgcttaa agtagagggt ggctttttga tattcttctt
    12661 gatcaaaata aagactggcc aactcaaaag ctgttaagtc atcgtattct aactccaggg
    12721 ctttttctaa aaactcagta gccgtttcaa atttccctaa ctgagcatag gcaaagccaa
    12781 ttcgttgata ggtggaaatg cccgtttgct cataaatcga gcgattatct aactgggcat
    12841 aggcttgaat agccgcttgg taattttcca actcactatc caactctgcc aaacccaata
    12901 tcaagagaga atcctctgag taggtcaagg cctccaataa tttctcacgt gccacatctg
    12961 tcaaaccttc cagctggtaa aggtctgcct tcagagccaa agacgagaca taccagtcac
    13021 tgtcagcttg gatttcctca agataggtaa aggcttcttc tatttgacca tcctcgctag
    13081 caattgcagc tagattaaga tgaacctctg gaaaatcctc tacaattttc aggtaaattt
    13141 ccttggcctg aggatagaaa ccaatccctt caagataagt tgccaactca tacagaagat
    13201 cacttgaatc attttctaaa gctttggcga aataatgctc agccttagtt aaatcttgct
    13261 cctccaaagc ctgtaacatc tgttgactat tgttcactct tgacttcctc accctctaat
    13321 tcatatagac cactgactac cttataccat tcgaaaatgg ctgaaatgac aaccttagca
    13381 gaggcataaa ccggaatacc aagtaaaact ccccagatac caaacataga tcctgaagtt
    13441 aacaaaacaa agagaacatt aataggatgg atgtttaatt gacttcccaa aatcaatgga
    13501 gagacaaaac ggccttcaat agtttgttct acaataaaga caatcactac tttcaaaagc
    13561 atgactggac cagcaatcaa acccaatact agggcaggaa gcatggctag aaagctacca
    13621 agataaggga ccagatttaa aataccagca gtaaccccca gcgtaaccgc atagcgtaga
    13681 ccaataatct tgaagaagat gataaacatt actgctacaa taatagccac tgtcacttgc
    13741 cctcgaacat agttggacaa ctgttgattc acatctgata gaacttgtcc aacaggttcc
    13801 ttcaattttc ttggaatgaa ttgggtcaaa tagttacgca agcctttccc atcacgcaag
    13861 agataaaaga gcatgaaagg aacgataatc aaggcaacaa tcacttgaga agctccgcta
    13921 ataaaggcac tcacccagtt gactgcctga gatgaaacct tacttgccaa aactgtagcc
    13981 tggctagaaa aattggtcaa aacttgctct aattgaggtc tgaaatcatc tggcaggtgc
    14041 tgggctacca atccattaac aatcctatct atatcttcta agtaaacagg aacgtttctt
    14101 gcaaaggtca aaacctgacg ttgcagattt ggaatggcga ctgccaagcc ccaaatgata
    14161 aagagagcga tgataacaaa gacaatagtg atagctataa cacgattaac cttatgcttc
    14221 tccatccaat caacaatagg attcaacaaa taatataaca aaccagacaa aatgactggc
    14281 aacatcacaa ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat cttacttaaa
    14341 ataaaaagat tcagtcccaa taataaggtt actaaaaata ccgtaattgc cttgttatct
    14401 aaaaaccact tgaaaaacca agataggcta aaatgtttct ctttttgctc cataaatact
    14461 tcctttctat tgtcctctca ttataccatt tttgaaacaa aataactctt ttttaaagtg
    14521 cttacatcta attggatatc tttaatttac ttgtttttgt gatataatag tcttatcttt
    14581 acacagaggt atagtaatga aagaaactgt ttattttgga acttatacac gtcgtacttc
    14641 tcaagggatt tacaaggcag actttgatac agaaactggt cagctttcaa atctagaact
    14701 ttttgcagct gagccaagtc caacctacct tgcctttgac cagcaccaac atttatacac
    14761 tgttggtagc caagacgata aggggggaat tgcagcctat caaactgacg ggactgtgtt
    14821 aaatcatgtt gttgaagaag gagctcccca ctgttatgtt gctgtcgatg aaaagcgtga
    14881 tttggtttac gcagccaact atcacaaggg acaagtcctt gtttataaac gccaggaaga
    14941 tggtagtctt ctacttagtg atatggatca acacagtggc caaggtccac atgaaaatca
    15001 agcttccccc catgttcact atacagattt aacacctgac cactatctag tgacctgcga
    15061 cttgggaact gaccaagtca tcacctatga cctcgatcaa gaaggaaaat tatctaagct
    15121 ctatacctat cacagtaagc caggagcagg ctcacgccat atcattttcc ataaccacta
    15181 taaaatcgct tatctcattt gtgaactcaa tagtactatc gaagttttaa tctacgatgg
    15241 cgttggcgaa tttgtacgta tgcaggttat ttcaacttta ccagaagctt acgaaggctt
    15301 taatggaacc gctgctattc atctctctaa agacggtaaa tacctctacg cttctaaccg
    15361 tggccatgat tctatcgcag tatataccat ccttgcggac ggtagcttag agttattaga
    15421 aatcgttcca acgcatggtc agactccacg tgattttgat ttgacaccca accaaaaatt
    15481 tctcattgtt gtccatcaag actctgacaa tgcaactgtc tttaaacgta attgtgacaa
    15541 tggtcgtcta gcagaactct ccaacgactt ccatgttccc gaagcagtct gcatccgttt
    15601 tgctccttaa aacaccataa aaaatgaact tggtattttc aagttcattt tttcttatag
    15661 tctatttccg acattaatac ggttaatggc acgttgcaaa gcaatcttag cacgacgttc
    15721 ttggtcaatc aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac gaagtttggc
    15781 acgttctgca cgactgatat cgatatcacg agcacgttct gcagagtcag cgacgattgt
    15841 gatcatatca ttggcaattt caataacgcc accgtttact gcaatccagt tcacgtgatc
    15901 tttatcatcg atacgtttta cctttacttc atcaactgct aaaaccgcaa tcatattttc
    15961 atgtcgtggc aagatcccca tctcaccatc cagagttcga accgatacat agctggcatg
    16021 gtgatcatag acgagaccat ctggtgtcac gatctggaca gttaactgag ccataggtca
    16081 cctcttaaaa tcccattttt tcagcttttg caatcacatc ttcgatagaa cctacaccac
    16141 ggaaggcatc ttctggcaag tggtcgtatt taccatcaag gatttcctta aagccacgta
    16201 cagtttcagc aactggaaca taagaacctg gctgaccagt aaattgttcc gcaacgttga
    16261 agttttgtga caagaagaac tggatacgac gggcgcgagc aaccaaggtc ttttcttcat
    16321 cagaaagctc atccatacca aggatagcaa tgatatcttg caattcatgg taacgttgaa
    16381 ggacacgttt tacttcagca gcaactgcat agtgctcttc tccaacgatt tcaggtgcca
    16441 aggcacgtga gcttgaagca agtgggtcaa cggctgggta gatacccaat tgtaccaact
    16501 tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc gctgggtcag
    16561 tatagtcatc cgctggcaca tagatagcct ggatagaggt tacagaaccc ttcttggttg
    16621 atgtgatacg ttcttgcaat tgacccattt ccgtagcaag tgttggttgg taaccaacgg
    16681 ctgatggcat acgacccaaa agggcagata cttctgaacc agcctgagtg aaacggaaga
    16741 tattatcgat aaagagaagc acgtcttggc cttccacatc acggaagtat tcagcgattg
    16801 tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc tgaccaaaga
    16861 ccatggctgt tttctcgata acgcctgatt ctttcatttc ccagtaaagg tcattcccct
    16921 cacgagtacg ttccccaaca ccagtaaata ctgaaatacc accgtgctct tgggcaatgt
    16981 tgtgaatcaa ttcttggatt aagacggttt taccaactcc ggcaccaccg aaaagtccaa
    17041 ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac cttgatccct gtttcaagga
    17101 tttcagaaga ggtagacaac tcatcaaaag ttggagcttt tttatgaatt ggctgacgct
    17161 ctgcgtcttc tgtaaaagga gcttccaaat caatggtatc tcccaaaacg ttgaagacac
    17221 gtcccaaagt ttctttacct actggtacag agattggacg acccgtgtcc aatacttcca
    17281 ttccacgagt caacccatct gttgattcca tggcgatagt acgaaccata ccatctccta
    17341 actccaaggc tacttcaagg acgatttttg tttttctttc gtcatttttg tagacgacaa
    17401 gtgcattgtt aatctcagga agtttttccc ctgctgcaaa caaaacgtct acaacgggac
    17461 cgataacctg agcaatttta cctgaactca tctccttctc ctattctata taagatactg
    17521 tcggttccta gctcaactag gtcctaagtt cattttcata cgagctggac tagagcctat
    17581 tctaaggcac tagcacctgc tacgatttct gtaatttctt gtgtaatcgc cgcctgtctg
    17641 gcacggttat actgaattgt caaatcattg atgactttct tagcattatc tgtcgctgtt
    17701 tgcatggctg tcatacccgc agcattctca gctgtcttgg catcgataat ggcaccgtaa
    17761 atcatacttt ctgcaaactg aggcaacaac tgctccagaa tttcttctcg gctggtttcc
    17821 aattcaaaag tcaagctgta ctcttcatcc gcttcatttg gatccaagtc aacaatcgga
    17881 agcatttgtt ccacacgcat ttgactggtt agcgtattga catggtggtt gtagcaaaca
    17941 taaagctcat caaagagttc attttggtac atttcaacag tttttgaaat aatcttacga
    18001 acttgatcaa agctaggttg gtctgccaag ccacgtaatt cataaagtgg ttgaataccg
    18061 cgagccttaa agaaatcagc tcccatccca ccgatacaga tcatttcaaa acctttaccg
    18121 tctgggtggt attcttcttt caactccata acagctttca aaatagagga attataacct
    18181 ccaaccaaac cgcggtctga agtgataacg atatagcctg tcttcttcac agaacggcta
    18241 atcaacatcg gattagttga agcaccagct ccattaccat gaaggatatc tgtcaaaagt
    18301 ttacgcactt tctgagcgta aacttggaag ttgcgagcag cttcttcaga acgacctagc
    18361 ttagcagccg ataccatttg catggcatta gtgatttgac tcgtattttt tgttgaggcg
    18421 atttttgttt taatatcatt tagagatact gccatctgac acctctattc ttattggaag
    18481 ctagattgat tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc tggcaagtct
    18541 tttgtatcac gaatggtttc caaaatctct ggatgttgag catcaaagaa ggtatggaat
    18601 tcttcctcga aacgaacaat atcatctact ggaacagtat ccaagaaacc atgtgtcaaa
    18661 gcataaagaa tggttacttg tttctcaaca ggtaatggtt tgtgaacagg ttgtttcaag
    18721 acctcaacgg tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc caagtcagaa
    18781 ccaaacttag taaaggcttc caactcacgg tatgaagcaa ggtcgatacg aagtgtacca
    18841 gcaaccttct tcatggcttt gatttgtgca gaaccaccta cacgagatac agatgaaccc
    18901 gcatcgatgg ctggacgaat acctgcattg aagaggccat cgccaaggaa gatttgtcca
    18961 tcagtgatag aaatcacgtt ggttgcgata taggctgaga tatctcctgc ttgtgtctcg
    19021 ataaatggta gggctgtaat tgatccacca ccaagttcat cagaaacttt agctgagcgc
    19081 tcaagcaaac ggctgtggag atagaaaaca tcccctggga aggcttcacg acctggagga
    19141 cgacgaagca agagcgatag ttcacgataa gctaccgctt gttttgatag atcatcgtat
    19201 acaatcaaaa catgcttacc ttgatacata aattcttccg ccatagcaac cccagtataa
    19261 ggagctagga agagcaatgg agatggttgt gaagcagagg ctgtcacaac gattgtgtag
    19321 tccaaggcac cgtactgacg aagtgtttct acttgcgtac gaactgttga ttctttttgt
    19381 ccaatcgcga cgtagataca gatcatatct tgatcttttt ggttcaagat tgtatcaatc
    19441 gcaatggttg ttttccctgt ctgacggtca ccgataatca actcacgttg accacgacca
    19501 atcggtacaa gggcgtcaat agctttcaaa ccagtttgca atggttctga aacagactta
    19561 cgttgcataa caccaggagc tggtgcttct actggacgag ttttatcagt gtggatttct
    19621 ccaagaccgt caactggacg accaagcgga tccacaacac gaccaatcag actttcacct
    19681 acagggactt ccatgatttt ccctgtacgg cggattgtat cgccttcacg gatatctgta
    19741 aagtcaccta ggatgataat accaacgtct gttgactcca agttttgagc cataccataa
    19801 gagccgtttt caaaattcaa caactctcca ctcatgacat tttcaaggcc atgagcacgc
    19861 gcgataccgt ccccgatata ggttacaaca cctgtttcag tcacatcaaa attgggtttg
    19921 aaattttcaa tttgttgctt aattaaagcg ctgatttctt gtgcgttaat tgccaaaaga
    19981 acaccacttt ctatttcaaa ttttctttaa caactttaag ttgttgttta atactcacat
    20041 caattgtctt gtgattggca aaaatgacaa aaccaccaat gagactttca tcgatttgtt
    20101 cttttacact ccttactttc agagacattt ttttctcaat caaagggagc aaacgagtct
    20161 tctgttcatc agttagagga tgagcagacg taatcgtcac ttcaaatcga tttgtttctt
    20221 tttcaagtcg gttcaagcaa tctacaagca catcataaaa aagatttgct ctgtgattgt
    20281 aggccagaac ctggataaag ttttgtaata aaggcgacac agaatcttgg aaaaaagcaa
    20341 ttgttttttc cttatccgac tcgtctactg ccacttgttt taaaaaagaa ggcagacctg
    20401 ttttttcaac aacttgcttg atttgagtca agtctgaaaa gatacggtct tcttctcctt
    20461 tttcaagtac caattggaca aaaggcatgc tgtatttttc aattaccttt actgttttct
    20521 tgtccattaa gcttctccta gctgatcgat atactgatca atgagtgctt tatgggcatg
    20581 actgtcaagg ttttgtgaga tgattttacc agctaagctg atggtcaaat ctgcgacctc
    20641 acccttaaca ctctgtaaag cttctacttt attttgagca atttcttgat tggctttttc
    20701 ttttaagtgt cctgcttcta gtttagcatc tgctaagata ttagccttac tttgctcagc
    20761 tgtttccttt gcattttcaa tgattgtctt agcttcttta cggctaccag ccaattcatc
    20821 ttcgcgtttt tgagccaata cttctgcttt ttgacgggct tcttcagctc tgtcaatatc
    20881 tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta atattagacc atgcaaattt
    20941 tttaatcaag actagcaaaa gaataaaaga gccagtgatt aaaataaaat taccaattaa
    21001 ttcacctact gttacgtgca tcagttactc ctttctattc ctcttcaata ttaatcttat
    21061 tccctaaata cacagatgtc aaaagagtaa aaacataagc ttggatgcag gaaataaaga
    21121 cagaaaatgc agtccaagcc aaattagctc caaaggctac tggataccaa taaatagctt
    21181 ggtgggaaag aagaagtaac aaactcgtca tgacctctcc tgcaaagata ttcccaaaaa
    21241 tccgcaaagc caaagataag aagtttgtaa attcttccaa gatattcatc ggtatgacaa
    21301 aaacaggact cataaaagat tttatacttt ttttaaatcc acgacgacga acgctttcta
    21361 tatgtgtcaa caaaatgaca agaaaagata aggttaagtc atactgtaaa ttagcggttg
    21421 gcgaactcca ccagttagtc ccatcgatcg tttgaagctt tgtcattaag ccaaggttat
    21481 tggcaatcac catgaaaagg aataaacaaa ggaaaaagag tgagtaatct ttcatgtagc
    21541 gcgaaccaat gttaggttct gtaaatccaa taacaaagtc atagacatac tcaagtacat
    21601 tttgctttcc tttgggtttc aaggtcatat tgcggcttgc ccaataaata aagacaaaaa
    21661 taactcccac aatcaacaaa gtcatggcta acatagtcag attgaagata acaggaccaa
    21721 tagagatgat tggattaata ctttcttcca tctaaaatcc tcccttttct tctcgttcca
    21781 tgtatttatt tgataataaa tgagaagaca agagttacaa agaaagttcc ttcaataaag
    21841 gcaacaccta aaaacatcaa actacgaaac tcagaaagca tatctggttg gcgtgctact
    21901 gatttaaaca gtccattcat caataaacct tcaccgacag atacgcccat acaggcaata
    21961 cataagccta aaaatgttaa attcataaca aattctcctt taaaataaaa tttacttact
    22021 tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg ctattggaag cgtttaataa
    22081 aaattatttc cattt
//
LOCUS       DAVBOM010000034        21565 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBOM010000034 DAVBOM010000000
VERSION     DAVBOM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.034"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            1..1024
                     /locus_tag="VQ878_001402"
                     /pseudo
     CDS             1..1024
                     /locus_tag="VQ878_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ878_001403"
     CDS             complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ878_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET3095734.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ878_001404"
     CDS             complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ878_001404"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET3095735.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(5187..5750)
                     /locus_tag="VQ878_001405"
     CDS             complement(5187..5750)
                     /locus_tag="VQ878_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3095736.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5835..6389)
                     /locus_tag="VQ878_001406"
     CDS             complement(5835..6389)
                     /locus_tag="VQ878_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET3095737.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(6400..7623)
                     /locus_tag="VQ878_001407"
     CDS             complement(6400..7623)
                     /locus_tag="VQ878_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3095738.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7660..10110)
                     /locus_tag="VQ878_001408"
     CDS             complement(7660..10110)
                     /locus_tag="VQ878_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET3095739.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(10310..11239)
                     /locus_tag="VQ878_001409"
     CDS             complement(10310..11239)
                     /locus_tag="VQ878_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3095740.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            11379..11666
                     /locus_tag="VQ878_001410"
     CDS             11379..11666
                     /locus_tag="VQ878_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET3095741.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ878_001411"
     CDS             complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ878_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET3095742.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ878_001412"
     CDS             complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ878_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET3095743.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13807..16353)
                     /locus_tag="VQ878_001413"
     CDS             complement(13807..16353)
                     /locus_tag="VQ878_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET3095744.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(16476..16916)
                     /locus_tag="VQ878_001414"
     CDS             complement(16476..16916)
                     /locus_tag="VQ878_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET3095745.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16891..17760)
                     /locus_tag="VQ878_001415"
     CDS             complement(16891..17760)
                     /locus_tag="VQ878_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET3095746.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17738..18238)
                     /locus_tag="VQ878_001416"
     CDS             complement(17738..18238)
                     /locus_tag="VQ878_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3095747.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(18249..18947)
                     /locus_tag="VQ878_001417"
     CDS             complement(18249..18947)
                     /locus_tag="VQ878_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET3095748.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18940..19176)
                     /locus_tag="VQ878_001418"
     CDS             complement(18940..19176)
                     /locus_tag="VQ878_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET3095749.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19276..20202)
                     /locus_tag="VQ878_001419"
     CDS             complement(19276..20202)
                     /locus_tag="VQ878_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET3095750.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20277..21092)
                     /locus_tag="VQ878_001420"
     CDS             complement(20277..21092)
                     /locus_tag="VQ878_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095751.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVICIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21096..21416)
                     /locus_tag="VQ878_001421"
     CDS             complement(21096..21416)
                     /locus_tag="VQ878_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3095752.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6504 a         4720 c         3807 g         6534 t
ORIGIN      
        1 tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca aaaaattgcg caaaagttaa
       61 ttgaaaagaa ttctatgacc gatattgccc atcagctggc catttcaact tcaactgtca
      121 ttcgaaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
      181 cttgggatga gtatgctttt acaaagggaa agatgagctt cattgcgcaa gattttgaaa
      241 agctcgatat catcactgtt cttgaaggta gaacacaagc tgtcatccga gatcactttc
      301 ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
      361 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      421 ctcccaggct gtttcactcc cgaatgctaa aatcgttctt gatcgctttc atattgtaca
      481 acatcttagc cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa
      541 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa
      601 actgagtgat aagcgatttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
      661 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
      721 cttgcttttt catttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
      781 tcttaagcag gctcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
      841 aaagattatc aacgcccttc aactacacta ttctaatgcc aaactggaag cgaccaataa
      901 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
      961 acggattttt atcgctttga atatcaaaaa agaaaggacg aaatttgtcc tttctcaagc
     1021 ttagctgact tcaacccact acagttgaca aagagcccag attaggaact atccgtgagt
     1081 tctctagtct ggagattttt caatagactt cgttattgaa cggttaccaa gttactcaaa
     1141 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
     1201 aaaagcaaac taagagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt
     1261 tgaagagatt ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggc
     1321 aaaaactcaa tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg
     1381 attctgctcc tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt
     1441 tttctcatat gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg
     1501 agaaatcttg tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc
     1561 gttaaatgct tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag
     1621 ttgctctgtc aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat
     1681 atcattcgtt gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc
     1741 taactcaacc attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt
     1801 ttgtggaata cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt
     1861 gacataaaca ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg
     1921 ctcactaact gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag
     1981 attttcttca agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac
     2041 aatagctgcc tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt
     2101 ctcaggaagt aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt
     2161 ctctttcata tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg
     2221 agcagcaatt tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc
     2281 attctcatat tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa
     2341 tgcttcataa agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc
     2401 atcaattagt ttacgataac cggcttccaa atcctgtaat tgatctggca attctgtaga
     2461 aagcgtagta accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt
     2521 ttctgtatta tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac
     2581 aaattgtgaa aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg
     2641 accatactgt tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc
     2701 atgaagaaca cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg
     2761 aattgccgca atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg
     2821 actggccttg agaaaacgaa atgaatggtt atagccctct gcttcaaaga gattattttc
     2881 aatatcggca aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc
     2941 cacttgactt tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg
     3001 aagattgtat agttcttctt ttctttcttc tagtgcctct aatctcccct cgtttcgctt
     3061 acgtagaaag attgccacta cataagccag aactaaaatg actgcaattg caaccattaa
     3121 ataaattagt tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga
     3181 ttatatcata ttttttagac caagggaact acttctccct attttttaga catcaagtgt
     3241 actatagaca gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa
     3301 catatcaaag attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg
     3361 atgttcggga tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt
     3421 ataacgctga atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag
     3481 tttgatttct tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac
     3541 accatagatt ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata
     3601 acgataaatc aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt
     3661 catcaaaacg agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt
     3721 tcccatggct gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc
     3781 tttttcaacg ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg
     3841 accagatttg gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc
     3901 agggttatta gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga
     3961 ttttttacgt gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagccaaaat
     4021 tcctttttct acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc
     4081 ttcactgaag aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt
     4141 ttgtccttca aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg
     4201 aacatcttcc cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata
     4261 atcattgata acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg
     4321 ggtatgaata ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat
     4381 ggctacctca actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat
     4441 tacatccttg ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata
     4501 atgcttggtt tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt
     4561 tagaaaggcc aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc
     4621 agtgaagatt tttgggtccg gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc
     4681 aactatttca agatctgcga caacatgacc acgacggtat tcttggtaat gaatcttacc
     4741 atttttgtga acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac
     4801 cccgtgaaga ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcgtgaag
     4861 gactgtaaag acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat
     4921 accacgccca tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg
     4981 gctggcaaat cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg
     5041 gtgaagacct tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc
     5101 taagccctct aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat
     5161 ttcttctgtc atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata
     5221 ctggtaaaca agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga
     5281 tcaccaatga caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg
     5341 ggatttggct ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct
     5401 atagaggttt tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga
     5461 cggccacctt gatttgaaat gacttccaat aggtcagaaa ctccttcaaa taaaatcggg
     5521 tgttcaagct ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga
     5581 gcgaatgtct caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg
     5641 tcttgtgtga taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa
     5701 ttatccagta aagttccacc taaatcccag atgtaatcgt gatatttcat atccttcatt
     5761 atagcatttt tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga
     5821 gaataactcc cgttttactg atttttacca aagacatctt gatagagcat tcctgttcgt
     5881 aaactctctg cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt
     5941 gaaggacccc gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga
     6001 ccatcaagga tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc
     6061 tctgcttgat tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc
     6121 tcgaagcttt gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc
     6181 atacctccag gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct
     6241 gctcttactt ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat
     6301 gtgatattgg ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc
     6361 tgagctaaca taactgctac ttttaccatg attttctcct tatttaattt gttttaatac
     6421 aacctttttc cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta
     6481 actcatcgat aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg
     6541 cgaaataaaa ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt
     6601 ctcaaagatg tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg
     6661 gttatttgat ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat
     6721 aaccaggaca gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga
     6781 ctctcgaact gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact
     6841 cccaatggca atctgtcctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg
     6901 attgagccaa gccaaaatcc gattaatttg gtaggtcggc attccaatct ggtgaagaaa
     6961 agctcgtccg tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt
     7021 cacaaatact gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa
     7081 aatggctaca aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac
     7141 tggaatggta aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct
     7201 ccattcctta tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga
     7261 tatcttcata aattctgacg gttggaatag ggtaattcca tttattgata cccagttttt
     7321 ggcacccgtt gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc
     7381 caagcctaaa atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat
     7441 gaccacaaaa ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg
     7501 cagaatatta ttgggataat catgactaac ggctatatag atagccacca caccgatgac
     7561 cagtagaaaa aatactggca agagcaaact gtaatcgact cttgagtcga gagaacgttt
     7621 catatatact aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct
     7681 atcaatagcc tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag
     7741 agatgctact atttgtttgc cgtatcgttt tccgacgatt ctcctatcca aaataagagt
     7801 taaggaacgt tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat
     7861 ggccattggc aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt
     7921 aatctttttc gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat
     7981 cacaaaagga tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat
     8041 ttgttgttca cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg
     8101 ggccaagtgg ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa
     8161 gagaaccaaa atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct
     8221 ggcatagact tctaaggagg tttctgttac cagagggaaa tctttgacca taaccacttc
     8281 ttgttcctgt tttccccgag attcaatctt gacaaatttg acttcaggat agcctaaaag
     8341 gtctgccaaa gaaaccctct gactaatctc aagagtagct gatactccca agacttggca
     8401 actctcagga agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat
     8461 tttcttttga ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg
     8521 aaccagctca tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattgtccag
     8581 agaatctaag atatttttcc tagatttacc agactgaaat tgttctatca agtagagaca
     8641 ctcaaagcga atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc
     8701 cttatcaatt aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag
     8761 agctaacaaa atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg
     8821 attatcttca agtctggtta cgagataggc atgattagtc actaaaagct tgcaagtctc
     8881 tgccctttct tgactacgtt tccaaaaatc ttccgtcaca aataagttct gggatgataa
     8941 attcccatca tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc
     9001 atccaaatct cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct
     9061 aaataagcga ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata
     9121 attttgtggt ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc
     9181 ttcttcttcc atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg
     9241 ctctttggat tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg
     9301 cgcttgaatc agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact
     9361 ttcttgttcc tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga
     9421 tagttttcgt ggctccagag aagctgccat tttcttaaaa tacagacctt gaacttggac
     9481 caagtctgga gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga
     9541 ctcatatagg agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg
     9601 ggtcatcttt tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc
     9661 tgtgtgtgcg tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt
     9721 ttccagttca gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag
     9781 ctcatagcct tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg
     9841 ggctacaaaa atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc
     9901 aggtgcttgc gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa
     9961 gggttcatgt ggattgacat ccgtcgtata gtgatcgacg atttctccat cctcaatcac
    10021 gacaattccc acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac
    10081 cacaacatag cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat
    10141 ttggcaccta caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc
    10201 ccatcgaata gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa
    10261 ttgagagaag aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatttaacca
    10321 tgtcaggatc gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac
    10381 gaacttcttc atccagcaag aaggcttgat catggctaaa gttgccctct tgaatcaagt
    10441 tacgcgcttg gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc
    10501 cttctagttt ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat
    10561 caaggtcatt gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc
    10621 tctctggatc acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga
    10681 tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag
    10741 caccgtaaac caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag
    10801 ctgatggaat ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt
    10861 taatctgacg actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac
    10921 catcgcggtt aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga
    10981 tttcttccaa gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag
    11041 cattgaccgc aacgatcaat tccttaccag catcatgaac caacttagcg atttcacgta
    11101 attggtcata actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga
    11161 tacggtctac gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg
    11221 taatgacaat cttttccata agaaaaatta taccacattt ctccaaaatc atccatgctt
    11281 tgaaaatgaa aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa
    11341 aaatgataaa ataggtatgt actgttaagg agagaattat gcccgtaaga aaattacaat
    11401 cctatgaggt agactatcaa gaagaattaa accagcagct tcctcattac caagcttata
    11461 cacctgaagc gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg
    11521 ttttttgtat ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg
    11581 ctcttgcctt tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta
    11641 ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc cccagttgga gcgatatttt
    11701 tattttttct ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg
    11761 ggtttattat ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg
    11821 gataatccta aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa
    11881 cggtcaaaaa ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt
    11941 aaataaagat tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta
    12001 tacttgacgg cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg
    12061 acaattgttc gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc
    12121 atctcatagt ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctctggc
    12181 ttaatcccat catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt
    12241 cggacttctt ccaaactcga tgcaatgctt tcactcacat ccataatggt agcttctggc
    12301 ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga
    12361 ctggcatttt ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg
    12421 accctagcta gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc
    12481 acaatcaatt gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca
    12541 gcagcatact tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga
    12601 tagatttctt cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct
    12661 ttcttttcta acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta
    12721 aagtccttat caaagagaat gacttccgta ttggaactga cattaggttt tatttctact
    12781 ttactagcgt ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata
    12841 gccagctgaa taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa
    12901 gtataaagac tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg
    12961 gtgaagacac cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta
    13021 agtttactga acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc
    13081 aaaagtggtt ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat
    13141 cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac
    13201 attttgattt tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg
    13261 agtatcttca actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa
    13321 ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc
    13381 ttctaggtag aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt
    13441 gtcatccaaa ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg
    13501 caattctttt aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa
    13561 gtcatagaca ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac
    13621 atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac
    13681 caataagatt tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct
    13741 taaaaaaaac tcaactctct gcattttaca tgagatagct gagttttctt tttattttag
    13801 gcttatttat gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct
    13861 aatcaagtca acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc
    13921 aaggtcagaa agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt
    13981 aaatacatga gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc
    14041 cttaatccaa gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg
    14101 agctaggaat tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt
    14161 ccaagaagta atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc
    14221 caactggcgt ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa
    14281 caagtcttta gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc
    14341 tgggagtcct gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc
    14401 ttctgcatca tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc
    14461 atctgattct ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt
    14521 agcaaccagt cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag
    14581 agctgaaatc acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt
    14641 atcaagaact ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg
    14701 ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc
    14761 ttctaacaag tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg
    14821 aagagctcct tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt
    14881 ttcgagtgta tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt
    14941 cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc
    15001 aactttgaca gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc
    15061 gacatcacgt cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct
    15121 gtattggtgt ttttcaaagt aggcgtgcaa acctttagca aaatcagcat ctcctagcca
    15181 acggcgaagc atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag
    15241 tgtattgatt tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc
    15301 gtcacgttca agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct
    15361 tggttcgatg gtatccacac agacgtattc catcatatta gcgaaacttt cattgagcca
    15421 aaggtcatcc caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg
    15481 agccacaaca agggcaactt gttgacggct agcaaatgta gagttttcat cgacaaccaa
    15541 gtaaacttca cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg
    15601 aagggcgatg tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa
    15661 ctcgatagag cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt
    15721 ggttgagtag acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc
    15781 accagcaaca aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat
    15841 acctgtttcc ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc
    15901 ttctgcttgg tcaaagcgaa gagagaggtc aaaagttgct ttggcttcag gctcatccac
    15961 acatgggaaa gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt
    16021 gactccatca actgtataat aagaagggta aatccctgtc atgttgtctg taattttacc
    16081 agaaaaggca agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc
    16141 attgtcatgg tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc
    16201 caagtctttt tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt
    16261 cccagaaaaa gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac
    16321 aaattgctta ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag
    16381 ctgctgctct tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg
    16441 acagcgattt ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat
    16501 tcttctaaaa caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct
    16561 gtgaaaaagt cctcatgaac ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc
    16621 ttaaaggcat gttgcgcaga aacttgattg aagagttcaa cagaaacctt tgtaatttcg
    16681 acaatgcaga cagcctgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga
    16741 agtggttcgt cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct
    16801 ttaaacacca aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca
    16861 tctccgatca aaggattgat ttgcttgtat ttattccaca tttcttgcgg tgtcatgggt
    16921 actcctttgt aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat
    16981 ctctaaatca aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg
    17041 attcattttt tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt
    17101 ctttcttgct ttatcctgca tatctcttag catatctaac attattggac tttccatatc
    17161 atgccattga ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac
    17221 tacaatcttt gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa
    17281 ttcaatcatc gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg
    17341 ttttaattgg tcggcatcat tgacaaaagg aaagataaca gatagattgg ggttggtttg
    17401 ataaacttct gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg
    17461 cctagttcct ctatagccaa acaagggatg cccttcgtca aaaaactctt tagtccccac
    17521 taaacaattg gcttctgtat tcgttaattc agtaaaacga taccaaactt cttcatctga
    17581 gtacagggag cagatagtct ctagataatc ttttacaaat tgctgacaac ttgctaatat
    17641 gatgttttga ttaagctctc tcaacaaata ttccccacga atcatgccga cgtggtgaaa
    17701 tagttgagga taaatttttt caagaatttt ttcgccacta agggcaagtt gatttctcat
    17761 cattcacctt ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag
    17821 acttaacctt aaagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc
    17881 aaatatatcc aagtgaatca ttcgcaccat cagacacagc ttccgaaatc gtaacttgag
    17941 gtgcactctc attcatttca acatcataca aggccatgac atggtgaacc ataaaatttt
    18001 ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa
    18061 atcccgtctc ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct
    18121 gactgcctcc aggtagatca taccgatgtt gataagggcc tctcgttttt tcaatgcaga
    18181 gtaacttccc attttctaag caaacagcgt agactccaaa gtgttttttg atttccatcc
    18241 aactcctcct acttcaaaga ccagccacca tctattgtca agatttgtcc ttgcatggcg
    18301 ctcgcttttc cacttgctaa aaaaagacta agctctgcta tttcctctgg ctcaatccag
    18361 cgcttgattg gggtttcact agccacccag tcagccaaac cacctggttc aaaatccgca
    18421 gcggtcatag ctgtcttgac tgctcctgga gcgataccaa agacctgaat cccagcttca
    18481 gcatagtcta gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag
    18541 gcgtgaccac ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc
    18601 tttttatttt ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag
    18661 ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca
    18721 tccaaaactc cggcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt
    18781 tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat caccctctaa gagtggcttt
    18841 tcaccttggt caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc
    18901 aatccgatcc ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca
    18961 atccgttgcc aaaacatcac aagctgtcgg gctccacatg gaaaaacctt ctccttctcc
    19021 agacacgttg attaagaaat aaggtgtcac ttcaagtgca agcccatttt gctcgatggt
    19081 atcaaagagt tggacatagt tttcagcacc tccccaacca gttcgtacat attttttctt
    19141 agcctttaag ccaggtagaa tttcttcaaa tgtcatgttt ttctccttta atgtcaataa
    19201 ttctcccctt cattataaca aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt
    19261 tacatcttct tctacttacg gcaaattatt ccctgcagca agataaattt cataccattc
    19321 ttttcttgtt aagctaaagt ttgccgcttg gctaacttct ctcaagtgct taggatttgt
    19381 ggtacctaca actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt
    19441 tgaagaggtt actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa
    19501 tttctcattt ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg
    19561 aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg
    19621 actatcttcc atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa
    19681 ttgtagctga ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat
    19741 aggattttga ttagaaactc caaaatctcg aactttacct tgtttataaa ggagatcaaa
    19801 ggcttctgct acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc
    19861 tagatgatca atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt
    19921 agaaaaatca aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat
    19981 cttttctctt aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc
    20041 acgaccataa atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac
    20101 aagctcttca acttctttta cagacttatc ttttattctc atcattccga gaacaatttc
    20161 tgataattct ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa
    20221 tttctaacat tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat
    20281 acttcactcc attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg
    20341 acagctaaag gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa
    20401 cggagcagag aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc
    20461 gcttctttcc aattccaaat acagataact agcgaaatcg taaagacaga caaactatcc
    20521 cagggagccg gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct
    20581 aaaacaacta aaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga
    20641 gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa
    20701 ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa
    20761 tcacttagta gttgataata acgtaatacc gccaggacaa gaattggcgt caaaagggac
    20821 tctttgatag aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc
    20881 ttacctagat aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc
    20941 atcaaataga tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa
    21001 ctttcccaca actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg
    21061 cttgtttctt cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct
    21121 actttttgac tcaaatcgtc ccattgttgc caaaagactg agacacgctc ttctccttct
    21181 ttcattaatg aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt
    21241 atccattgat ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta
    21301 tcaaatccag cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca
    21361 atcatatcca agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact
    21421 tctcccttct aatctatttt gtaataccta ctagtaactt cacctatagt atatcacttc
    21481 tacactagtt tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca
    21541 gcgtcgccct accgtatgta tggtt
//
LOCUS       DAVBOM010000035        21358 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBOM010000035 DAVBOM010000000
VERSION     DAVBOM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.035"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1343)
                     /locus_tag="VQ878_001422"
     CDS             complement(<1..1343)
                     /locus_tag="VQ878_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET3095753.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATFSNMANKSQTEQGEINIERDKAKTAVSEYKEKKVSEIYTKLERDRHKDTVDLVN
                     KLQEIKNEYLNKIVQSTSKTEIQGLITTSRSKLDEAVSKYKKAPSSSSSSGSSTKPEA
                     SDTAKPNKPTELEKKVAEAEKKVEEAKKKAKDQKEEDYRNYPTITYKTLELEIAESDV
                     EVKKAELELVKEEAKEPRNEEKVKQAKAKVESEETEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAPKPENPAPKPEKPAEQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNG"
     gene            complement(1422..1949)
                     /locus_tag="VQ878_001423"
     CDS             complement(1422..1949)
                     /locus_tag="VQ878_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET3095754.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAVVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(2032..3363)
                     /gene="hk06"
                     /locus_tag="VQ878_001424"
     CDS             complement(2032..3363)
                     /gene="hk06"
                     /locus_tag="VQ878_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET3095755.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDIYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(3360..4013)
                     /gene="rr06"
                     /locus_tag="VQ878_001425"
     CDS             complement(3360..4013)
                     /gene="rr06"
                     /locus_tag="VQ878_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET3095756.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(4655..7087)
                     /locus_tag="VQ878_001426"
     CDS             complement(4655..7087)
                     /locus_tag="VQ878_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3095757.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYELDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQACSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7089..7547)
                     /locus_tag="VQ878_001427"
     CDS             complement(7089..7547)
                     /locus_tag="VQ878_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET3095758.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            complement(7666..8394)
                     /locus_tag="VQ878_001428"
     CDS             complement(7666..8394)
                     /locus_tag="VQ878_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095759.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(8394..9401)
                     /locus_tag="VQ878_001429"
     CDS             complement(8394..9401)
                     /locus_tag="VQ878_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3095760.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(9439..10197)
                     /locus_tag="VQ878_001430"
     CDS             complement(9439..10197)
                     /locus_tag="VQ878_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3095761.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            complement(10160..10450)
                     /locus_tag="VQ878_001431"
     CDS             complement(10160..10450)
                     /locus_tag="VQ878_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET3095762.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAVQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(10521..10623)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10706..12052)
                     /gene="cbpD"
                     /locus_tag="VQ878_001432"
     CDS             complement(10706..12052)
                     /gene="cbpD"
                     /locus_tag="VQ878_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET3095763.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     gene            complement(12141..12407)
                     /locus_tag="VQ878_001433"
     CDS             complement(12141..12407)
                     /locus_tag="VQ878_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095764.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(12409..13761)
                     /gene="dnaB"
                     /locus_tag="VQ878_001434"
     CDS             complement(12409..13761)
                     /gene="dnaB"
                     /locus_tag="VQ878_001434"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET3095765.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(13805..14257)
                     /gene="rplI"
                     /locus_tag="VQ878_001435"
     CDS             complement(13805..14257)
                     /gene="rplI"
                     /locus_tag="VQ878_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET3095766.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14254..16227)
                     /locus_tag="VQ878_001436"
     CDS             complement(14254..16227)
                     /locus_tag="VQ878_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET3095767.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(16363..16911)
                     /gene="raiA"
                     /locus_tag="VQ878_001437"
     CDS             complement(16363..16911)
                     /gene="raiA"
                     /locus_tag="VQ878_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET3095768.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(16991..17653)
                     /locus_tag="VQ878_001438"
     CDS             complement(16991..17653)
                     /locus_tag="VQ878_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET3095769.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(17650..18948)
                     /locus_tag="VQ878_001439"
     CDS             complement(17650..18948)
                     /locus_tag="VQ878_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3095770.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RFGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            19004..19639
                     /locus_tag="VQ878_001440"
     CDS             19004..19639
                     /locus_tag="VQ878_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET3095771.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            19924..20844
                     /gene="cysK"
                     /locus_tag="VQ878_001441"
     CDS             19924..20844
                     /gene="cysK"
                     /locus_tag="VQ878_001441"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET3095772.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(21041..21310)
                     /locus_tag="VQ878_001442"
     CDS             complement(21041..21310)
                     /locus_tag="VQ878_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3095773.1"
                     /translation="MGLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADET
                     SYRVLESDSQLTYYWTFLSGKAEKQGITLYHHVLIDLFISYFNPL"
BASE COUNT         6279 a         4823 c         3538 g         6718 t
ORIGIN      
        1 ccattgtatt ggagccatcc tgtcgccatt gaaccattag cgtttaggta gtaccatgaa
       61 ccattgtttt ggagccatcc tgttgccatt gaaccattag cgtttagata gtaccatgaa
      121 ccattgtttt ggagccatcc tgtcgccata gcgccattgc tgttgaggta gtaccatgag
      181 ccattgtttt ggagccatcc tgtcgccatt gaaccatcag tattgtagaa gtaccacata
      241 ccgttttctt gtttccagcc tgtttttgga gtagatggtt gtgctggttt ttcagttttt
      301 ggcggttgct gttgagtcaa gcgattatat tcttcttctg atctacgagc atagtcttct
      361 tcagcttgtt gttcagctgg tttttctggt tttggagctg gattctctgg ttttggagct
      421 ggattctctg gttttggagc tggtttttct ggttgaggag ccggcgctgg ttttggttgt
      481 tcagctggtt tttctttaac tttatcttct tctgctgctt ttcgtttagc ttcttcttct
      541 gcttttttac gatctgtctt gattttttct aaccttgtag cctcagtttc ttcactctca
      601 actttcgctt ttgcttgctt aactttttcc tcgtttcgag gttccttagc ttcctctttt
      661 actagttcaa gctccgcttt tttaacttcc acatcggact cagcaatttc aagttcaagc
      721 gttttgtaag taatggttgg gtagttacgg taatcttctt ctttttgatc cttggctttc
      781 ttcttagctt cttcaacctt cttctcagct tctgctacct ttttttctag ttctgtcggc
      841 ttgtttggct tcgctgtatc tgaagcttcc ggtttagtgg aagagcctga acttgacgaa
      901 gaagatgggg cctttttata tttagacaca gcttcatcta gttttgatcg acttgttgta
      961 ataagtccct gtatttcggt ttttgaggtt gattgaacta ttttattcaa atactcgttc
     1021 ttaatctctt gcaacttgtt aactagatct acagtatctt tatgtctatc tctctctaat
     1081 tttgtataga tctcactcac ttttttttct ttatattcac tgaccgctgt ctttgcctta
     1141 tctcgttcta tattgatttc tccttgttct gtctgacttt tatttgccat attagaaaaa
     1201 gtggctgctt gggtacttcc ctcgttctct gtcgcatgaa ccacactccc cataacaaga
     1261 ctggcaacta ctacactagc tactccaata ctaaatttac gaattgaata atgtactttt
     1321 ctttcgcttt ttgatgcaaa catgtttatt tccttctata ttttttcttt aaccttacta
     1381 tatcacttca atatgaactg tatataaatc gaattttgta tttatctctt tatgcttcca
     1441 tttgggatta taacttcatg taatagcttt tcctcttcag ctattcgtcg atacaaaata
     1501 actgcataaa ctggaaaaac taaaacaaaa gtcacataag catgactcaa caaggtcaag
     1561 ccaatcaact caggaagaat atttaaaaag taattaggat gttttactgt cctaaacaag
     1621 atatgatcta catatttgtg attattgaca agcataagct tcactgtcca aatatctccc
     1681 aacaagtgaa tcaccaacat caacatcagc atagaaaaaa taagcaagac caaaccaacc
     1741 atacccatgc catcaaaaat tgtcttgtgc accactgcct caaccaagca agagagataa
     1801 aaaacaatat gagccatagt taatcgtttt gtattctcaa ctccaaattc tttcccgcca
     1861 ttgctaagga ttcgtttctc attctctatc gaacgcttta aaaaaatcaa tcgaataaag
     1921 aatgttacta aaataatcgc taataccata ttagtatcct ttcttttatc tatgcaaaga
     1981 ataacacact tatgttaacc ctatatgaac tttaataaaa aactaatctg tctacaagct
     2041 aatcttaaat tccataccgt gttcataagg gagaaaacta tagtccattt gatagctttc
     2101 taaaatatta ttcacaatgt aaagacccaa accggaactt tcatccttat ctgtcacgat
     2161 ttgagaatga tagaatatat caaataaatg ttctagttct tggtcactta gaggcgcaca
     2221 tgtatttttg atagagagat agccatcttg ctcggatatg attacgcgcc catttttatc
     2281 tgaatattta attgcattac taatcaagtt tgtcaaaacc ttatccaatg ccctaagact
     2341 catgacgacc ctggtagcat ctgtcaattg attttcaatt gtaacaccta ttgaatgagc
     2401 taattcttga taacgtgata aaatatctac taaaactggc ttaacagtca aggtctcacg
     2461 acactctgtc cactcttgga atttagaaga ctccagtact tcttctaata agtggctcat
     2521 ctggtcaatc ttatttatac tctttgcaat atattttgga tgatctttgt aatctccaat
     2581 attatgctgc atattctcta ggataattct aagactggct aaaggggttt tcaactcatg
     2641 tgatgctcca cggacaaagg aaaccttttg attttgcaat tttacaattt gctcattacg
     2701 actttccaac tcatgaataa ccttcaacaa gtgctcatac ataccattaa tctgttttcc
     2761 aacttcacca acttcatctt tcctactttc atcaaaacga atattgtcat ccaaatcttg
     2821 cattttacta gtcacttctg aaatgtaaaa aagaggattg agcaagcgtt tagtataaaa
     2881 ataagaaaaa acaaaggaaa aagcaattgt aaccaaaaat gtatatggga gatacaaaag
     2941 caaaatattc tttgcttctt tgtagatatc caccccgtga acaaattgca ctgttacctg
     3001 tttaccatct gctgtactaa cagacatatc taacatcacg atataatttg atagctttcc
     3061 atctttaata tccaagtcat gcacaagagg gagccgctta tctacaatat ctcttttaag
     3121 gtgagcagat atggtcaagg actttgaata agactggagt aagcttggaa tttcatcaga
     3181 tgtcttagtc tttaaatact ccgtaaacac tcttgcgctc tcattaaact tttccccctc
     3241 cagttgaata taataaaaag gaaaggtcaa ataaatagct atatgaatga ctagaccaac
     3301 accacctaga attgcaaaac ttcttaaaaa agacttggtt aataatttag gattttttat
     3361 cataagctaa tcttataccc aacatttttc acagtcacga tacaatctaa agctaatttt
     3421 ttgcgaagag tacgaatata gacatcaacg accctatcac aaggtaaatc agctacatct
     3481 tttgaaattt cttccaatat ctgctctcta cttaaaactt gatttttatg ctgaatcaaa
     3541 cactttagta ccagtaattc ctttggtttg agatcaattt cttcattttt ataatgtgct
     3601 ttgtaagagg taaaatccac tgttacatcc tgatatcgcc aaatatcctc tatgacgtag
     3661 taacgtctga taagcgcctt aatacgcttg acaagcagta ccaaagaaaa aggttttgtc
     3721 acatgatcat cagcatagag atcaaatacc tgtgactgag tagtttcatc tcccagagca
     3781 ctcaagacga tgacaggaat atcgtgcttt tgattgattt cttttaacac ttcaaaacca
     3841 ctcttcctag gcatcattaa atccagtacc atgagatgga tagggagatc ttgaaatttt
     3901 tccaagacct cttgtccatc cttagccata atgacatgat aaccctcttc tgtcagaaat
     3961 gctgcaattc cttctctaat catttcctcg tcatctgcaa ctaaaatgtt catctctctc
     4021 cctttctact accagaactc catacatcta tttcctgtat gctatttgaa aatttcctac
     4081 cagcctatca tctatgataa tggaatggat ttcatttatc cgctactttt tgtcaacaac
     4141 aacgtcaata caagaaaatc attcatcttg cagcttatac tcttcgaaaa tctcttcaaa
     4201 ccacgtcagc tctatctaca atctaaaaac agtgttttga gcaacctgtg gctagctgcc
     4261 tagtttgttc tttgattttc attgaatatt agtttgattt ttcaaatacc agctagaacg
     4321 gatttgacat gcaaaaaaga aacaggtctc ttttgaaaga ataaaaattt cagataagac
     4381 tgctcttttt ctactacaca cgctctaaga caaatacgac ggagggtaat aaacatatga
     4441 attttgtgtt gaatggtgaa aaccacggat cgtttagaag ctataggttt tagtttcata
     4501 ctcttcgaaa atctcttcaa accacgtcag ctctatctgc aacctcaaac cagtgttttg
     4561 agcaacctgc ggctagctgc ctagtttgct ctttgatttt cattgagttt cactccactg
     4621 tgacttatgg tcagatgctg atacttttat tcttttatgc aatatcaaat tttaactggc
     4681 ctgctttgac accaatctta agtgtgctgc ctgccactaa atctccctta agaagaagtt
     4741 ctgccaactt gtcctccact tctgtttgca gggttctgcg aagtgggcga gctcccatct
     4801 ctgggtcata tccttgattt gctaacaatt tcagagctga agcttgtaat ttcaagtcaa
     4861 tgcctttttc agccaaactt gccactaaag gcttgaccat aatcttcacc acttcctgca
     4921 tatggtcact agataggcta tggaagacca ccttctcatc aatacggttg atgaattccg
     4981 gtctataagc ttttttcagt tcttcaaaca tgcgtttttc catattttcc tggtcaaaac
     5041 gaatatcctt agccccaaaa ccaacagtct tatcatcacg aagggcagtc gcacctaggt
     5101 tcgatgtcat aatgataatg gtatttgaaa aatcgacctt gcgtcccttg ctatctgtca
     5161 aaacaccgtc atccagaact tgcaagagaa cattaaagat atctgggtgg gccttctcta
     5221 cctcatcaaa gaggagaacg gaatagggtt tattgcgaac cttctctgtc aactctccac
     5281 cttcttcgta acccacatag cctggaggag ctccatttag acggctggct gcgaatttct
     5341 ccatatactc actcatatca aagcggataa gggctgattc gtcatcaaag agaacttctg
     5401 ccaaagcctt ggccaactcg gtcttaccga cacctgtggg tcctaggaac ataaaggaac
     5461 cgatcggacg cttgtgactg cgaattcctg actgattacg gcgaatcgca cgactaatgc
     5521 ttgaaacagc ttgatcttga ccgatgacac gtttatggag ttctgcttca agatttagat
     5581 acttcttagc atccgtttga gtcagttttt gaactgggat tcctgacaag cgactcaagg
     5641 tggtcaaaat atcagactct gtcaccaagt ctttgtagac aggtacttcc tcttcttttg
     5701 cgattagctg ggctgcctgt ttccacttgc catccatcag ggccttatca gctggactca
     5761 aatctgaatc gtctgctttt acatacttta ccttattttg cactgttgct gctgcttcgt
     5821 ccaagaggtc gatagcagag tctggcaagt gacgactggt taaataacga tgagccatct
     5881 taaccgctgt ttcaaccgct tcatctgtga tttgtacacg gtgatgtttc tcataagtcg
     5941 ccttcaaacc ttgtaaaata gtcatactat ctgccacact tggttcttca atcgtcactt
     6001 tagcgaaacg acgagaaaga gccgcatctt tttcgatatg tttttgatat tcttcctgag
     6061 tggtggcacc aaccgttctc aaagttccac gcgccaaggc tggtttcaag atattggccg
     6121 catccagagt cgaatcaatc ccgctaccag aacccatgat ggtgtggagt tcatcgataa
     6181 agaggatgac ttggccatct tcttcaatat ccttgatgat attattcatg cgttcttcaa
     6241 agtcaccacg gaagcgtgtc cctgcaacga cattcatcaa atcaagttct aacacgcgca
     6301 tcttagccat ttccgcaggc acgtcaccac tagcaatacg ctgagcaaga ccaagcgcca
     6361 gagctgtttt cccgacacca gcatccccaa ccaagacagg gttgttctta gtcttccggc
     6421 tcaagatttg aatcatacgt gagatttcct tgtcccgacc gatgactggt tctaacttgc
     6481 cagaacacgc ttgctctgtc aaatcatgcg tatagtcctc gagaccacca ctaggagtct
     6541 gcggcatgcc catcatattg gccatagaat tttgcttgtc agctactgta cgatggcgtt
     6601 ggcgtaaagc cttgagatct tcacgagtcc agcctgcccg ttcttctaaa tttcgacgaa
     6661 gagcagcaat cttgacctga tctttcttgt cttcataaga aaaaccagcc ctctccaaga
     6721 tacgagtcgc caaggcattg ccatcatgca aaatcgcata gaggacgtgc tctgtcccta
     6781 gcaccttagc atggaccact gacgctacat actctgcttc gtcaaaaaga atctgcaaac
     6841 gacgggagaa cggcaattcc gtaaaagttt catcctggct atagtccgtt tcagtcagtt
     6901 ccaaagccac ctcttctaaa cggtccagct catacggata atcatttaaa gttgcccctg
     6961 ctacactata actgtgatta gacatggcaa tcaacaagtg ccaagactct agataacgag
     7021 ctccaaaatg tccagcaacc atgtaggcac tttcgataca ttcattcaat gcttttgaat
     7081 agttcatctt acttcccttt tctatctacc tcttgtatga tctgacgtag catgtttgct
     7141 cgaacaactg gagcttcttc tcctaaaacg cgatccaaag ctactgattc tagcaaattc
     7201 atctcctgct tggtcatcaa ttcctgctca accaaaagct ggagaatatc ctcataaatt
     7261 tcttgactga ctcgctcacc aatcgagtaa agcagctccc ggagcatttc atgatgacta
     7321 gaaaactcaa ttcgtcctat acgaatgtag cctccaccac cacgcttact ttcaaccaag
     7381 tagcctctac tttccgtaaa gcgtgtcttg atcacgtagt taatctgact aggaacaacc
     7441 tgaaaggtat ctgccaactg actccgttgc aactccacga taccagattg atctaaaatc
     7501 gccttgatgt aggcctcaat atgatccgat gtatttttaa atctcataac aaacccacct
     7561 ctctctttaa accttgacct tgtttgacta ttataccgaa attttctcat ttttaaaaga
     7621 aaaagggcgc tggtaaagga taatcttcac caactcccta tttttctact tatctaagcc
     7681 taattctgcc aagatttgac gtttgtaggc aatcttttgg acttccttgt cctcatcttc
     7741 agaccaatct agtttaattt ctgaaacaat ctgcccaggg cgatttttca agatatagat
     7801 gcggtcgctg agattgaggg cctcctcaat actatgcgtg atgatcaggg ttgttagctg
     7861 caactgcttg tgaatctcaa gataccaagc gtggagttcc atctttgtca tctcatccaa
     7921 agcgctaaag gcctcatcta agagaaagag cttgtgccca aaaaggtagg tccggagtaa
     7981 ggctacacgc tggcgcatcc caccgctaag ttcatgagga tacttgtctc ttacagctgt
     8041 cagctggaag gtcgcaagaa ttttatccgc tcgggaaata gcttctgcct tatccacctt
     8101 ttgaatcaag aggggcagaa tgatatttcc aagcaccgtc ttgtgctcca agagcagatc
     8161 cttttgcaac atataactca cgcgcccctt gggattttct tcaccatcaa ggacaattct
     8221 ccctgactga acttctaaaa tcccagcgat tagattaaag agggtggtct ttccaacacc
     8281 acttgggcct aggatggaaa ccacttcgcc tgaagtcacc tgtaggttga tatcctctaa
     8341 aatcctctcc tgaccatagg cataactgac gtgctctagt ctaatttctg tcattatttc
     8401 acaaattcgt tggtgaagcc tttgtctgtc aagtcttctt taaggatacc attttcttta
     8461 tcccatttat agaaagcatt ccagcgagct gcgtcaaatt gaccccattt ttccttgtcg
     8521 cttgcgtatt cttttgacaa gtatttttga gattcgatga caaagtcacg tttttccttg
     8581 agttcaggtg cattcttgat gagaatatct gcagcttctt ctggatgttc catggcatat
     8641 tggtagcctt ttttgatggc ttggatgact ttgcgagctt cttctttgtt atctttcaga
     8701 tagtcgttgt ttgcgatgat aactggtgaa tagtagtcaa actccttgac atagtctttc
     8761 aagtacatga agttagcatc tacaccttga gatttagcaa ggataccatc ccaaccgtag
     8821 taaatccaag cagtatcaaa gacgccattg gcaatcggtg tgattgagtt tgagtcgtta
     8881 tttggtactt tttcaacctt ctcaaagtct ccaccttgag attctaccaa ggttttcaac
     8941 atagcaagtt cagttgggtc attccatgtc ccatatttct taccaaccaa gtcttttgga
     9001 ctgcttacat tatcagattt acgagagatg attcctgatg tattgtgttc aacaatagct
     9061 gcaacggcag tgattcctgc tcctttttcc aatttcttag ccatgtagtc ttggaaatac
     9121 actgcaaatg gtgcctttcc gttgataacc aagtcagaag aactttcttc tggtggcaat
     9181 ttcaaatcaa catccactcc agcttctttg aaataacctt tttccttggc aacataaagc
     9241 cctgtgtggt tggtatttgg tgtccagtct aggataaagt caaccttctt aagttctgcc
     9301 tctttgttgt ctttagaagc agttccttga ccacaggcca caagcacaac agctacaaga
     9361 gctgttacaa gcgttaaaaa cactttccat gttttcttca ttttgatttc ctcttttctt
     9421 tttcaaaaac gctctatttt aagtacgttt ccatttaatc acatattttt cactgatatc
     9481 gaccagcttc atacccaaaa gactgataat cgacaccaga ataataatgg caaacatggt
     9541 atcatactga aacagttttt tagactgaat catataaaca ccaagacctt caaaacctcc
     9601 caaccactca gataccacag ttgtgataaa ggcgtaggag acactgaccc tcagacctgc
     9661 ataaaagtaa ggcaggctaa ccgggatttt aaaatgccac aggatttgcc aagggtttgc
     9721 tcgcatcaga ctaaacaaag tcagcatatc cttgtcacaa tgcctaaaac cgtccaaaat
     9781 actaacgatg atgggaaagg ttgttgttaa gataatcaag acaatcttgg gcaaaatccc
     9841 ataacccagc cacaagacca ggataggagc tatggcaatg gtcggaatgg tctgaatgac
     9901 caccatcata gggtaaatca ggtcattgag ccaagtcaaa ctatccatga gcacagccat
     9961 aagacaggca atcaaaactc ccaaaatcag ccccagtaaa gccactctca aggtcgccca
    10021 gctatggtgc cagagaaatt ctctgtcacg aacaaagggc tggagaattt caagaggtgt
    10081 cggcaggata aacttgggga gaagtttaag aaaacctgct aactgccaga ttgacaatac
    10141 tccgagaaag cccaatagac taatgtgtcg tctcagtata cttttcaagt ttctcatcaa
    10201 tacttaaaat ctctcctaca tttattttga cattggcaaa gacattgtct gcctcctgca
    10261 ctgccacttc cagcgcttct tttagaatgc gcataagctc atcaaactcc ccttccaaga
    10321 ccgtttcaaa tggtgtcact accatcgtca cttcttgagt ttgcagataa gcaatgacct
    10381 gatcaataac agctatccga tcaatcccct gtgctagggg taaaacttgc aaggcaatgc
    10441 ttgctttcat aagaacctcc tcttctcgtt ttccttttaa aaaaaagaaa aacctttacc
    10501 atacatggaa aaggtgcaaa attagactaa gtatcgttcc ctccgctggc attacccaga
    10561 tcaggtgcgg tcgaagttta acacttcctc tcagactgta cacagactcc catatattat
    10621 atgtatatat gatagcgcaa aataagaaaa atgtcaagga aactgcttac agaaaagagc
    10681 aggaaatttc tcctactcca attttctata ctcgttctcc atcactgttt actctgtagc
    10741 catccaccgt cgtattaata gctaaggcgc ctgaagagta agaataatac cacttaccag
    10801 agacctggta ccagcctgtt ttcattgccc ctgaactacc cagataatac cacgagccat
    10861 tctcctttaa ccatcctgtc tgcatttcac cagataattt caaataatac cagctagaac
    10921 cgtctttcag ccatcctgtt gatttagaac catttgattt gaaatgatac caactaccat
    10981 ttattttctt ccaaccgaca gttgaactat tattggatcc atagctagag atatttcctg
    11041 attgattctg ataattttgt gaagaagtca ctccctctag ctgtatatag cgacgacttc
    11101 cgttataagc cgtataactc aaccacttat agccgtcttt ttcaagtatc tgatcataat
    11161 gaaccttctc tccaggataa tagtaatcaa tcacagttgc actaactagg ggttcagttt
    11221 taatagcaga cttgatctta aaataatgag ttcctcctgt tgaagaaaga acagaattac
    11281 ctagaggatt tttattcaca gcctccaatt gaacataacg atagcttcca ttataggcag
    11341 tataactcaa ccacttatag ccgtcttttt caagtatctg atcataatga accttctccc
    11401 caggataata gtaatcaatc acagttgcac taactagggg ttcagtttta atagcagact
    11461 tggtcttaaa ataatgagtt ccgcctgttg aagctgagga ttgactattc ccaacactgc
    11521 cactatccaa atctttaaaa tgaataaatc ctgtcatcgt gtttgctttt ataactcgtt
    11581 tattatagga ttctgtataa ccatagttat attcctcaat ctcaatctga tctcccatta
    11641 catttgacac ccaggcaaca tgaccataag ttcctgcagt agaccaagta atggaaccaa
    11701 tcgtcggtgt attatctaca cgataacctt cccgacgagc acgatgtccc cattcattcg
    11761 catttccata agctgccgga atttcaaaac cattgacatt actcaaacga aaggctacaa
    11821 aagaagtaca ctgacgagaa tacatgcgcc actgatcaat ctcctggctc ccatttttat
    11881 aataagcagg ataatcatcc ccacgcgcaa tcgatccatt tcctctggaa taggcataga
    11941 cactatcacc agctgctagc atcaatccta ctactaaaaa aggaacaagc tttttaactg
    12001 acatcttcaa gtaataactt gttcctcttg ctataaacgg taaaattttc attcttcctc
    12061 cttaaaaaat aatataaagc gatgattgcc ttcacctaaa ttattcggag aaaaaagaaa
    12121 aagtgagaaa atttctcact ttagtcaaga taatgaatca aattcttttc tgtaagaata
    12181 tctgagtaag taaaggattc aacgtaaaca ttaacttgtt tatctccttc cacatcccca
    12241 aactccacaa taaataggga tggataaact tcaattagct tacccaatct atttttttgg
    12301 cgcttacgac cattctccaa agtcatttct acgacttgtc cctcatgtgc cttgatttct
    12361 tctttgattt ttttcatctt ggctacatct gtaaatgcat ctgacatctt atgcctccct
    12421 ctttgagata cttgaaaatt tattgtattc tttttggaaa atcaattcca ctgttccacg
    12481 agctccacta cggtttttct cgataataac ttccacctta ttatttggga taccctcctc
    12541 ttcttcacca ccacgttcat agtagtcatc gcgatagaga aaagctacga tatcagcgtc
    12601 ctgctcaata gacccagatt cacgaatatc agacaagacc ggtctcttgt cctgacgttg
    12661 ttctacacca cgagaaagct gactcagagc gattactgga accttcaatt ccttggctag
    12721 tattttcaac tgacgagaaa tttcagaaac ttcttgttga cgattttctc gaccagttcc
    12781 cgtgataagt tgcaaatagt ctatcaaaat caaaccaaga tttccagttt cttgagccaa
    12841 tttacgagaa cgagaacgaa tctctgtaat ccgaatacct ggcgtatcat cgatatagat
    12901 actggcgtta gctagattac cctgagcaat agtatatttt tgccactcct catctgtcaa
    12961 ttgccctgta cggatagaat gtgactccac caagccttct gcagctaaca tacggtctac
    13021 caagctttcc gcacccattt cgagtgaaaa aatagcaacc gttttgtcca acttagtccc
    13081 aatattctga gcgatattca aggcaaatgc tgtcttacca actgctggac gagctgctaa
    13141 gataatcaac tcctcctcat gaagtcctgt tgtcatatga tccaaatcac gataacctgt
    13201 cgcaatacct gtaatatcgg tcgtttgttg cgagcgagct tccagatttc caaagttgag
    13261 attcaacaca tctcgaatgt tcttaaaccc gcttcgattt gcattttcac tgacatcaat
    13321 caaccctttt tctgcctgag caataatttc atcagctggt tgtgacgctt cgtaagcttg
    13381 gttgacagac tctgtcaact tggcaattaa acgacgtagc attgcttttt ctgcaacaat
    13441 cttagcataa tactccgcat tagcagaagt tggcacagaa ttaacaatct caaccaagta
    13501 agacaagcca ccaatattct gtaaatcacc ttgattatca aggatagtac gaaccgttgt
    13561 tgcatctatg gcatcaccac gatcggataa atcgaccatg gcttggaaaa tcaaacgatg
    13621 ggcatactta aaaaagtccc gagactcaat gtattctcgc acaaaaacaa gtttactctc
    13681 atcaataaag atagccccta aaacggattg ctcagctaag atatcttgag gttgtactcg
    13741 taactcttct acttctgcca tcagacttcc cttcctttta caatcttgtc aagaaggtgt
    13801 aaacttatcc ttctttcaca cgaagattga ttacacttgt gatatcttga tagattttca
    13861 ctggcacatc aatcaaacca accgctcgaa tcggagcttg tacttgaata tgacgtttat
    13921 caatcttaat tccaaattgc ttttgcaatt cttctgcaat cttcttattg gtaatagaac
    13981 caaaggtacg accatctgga ccaacttttt caacaaattc tacaacagtt tcttctgctt
    14041 caagttgtgc tttaattgct tttccttctg caatcatctc agcgtgagct ttttcttccg
    14101 atttttgttt accacgaagt tcacctacag cttgagcagt cgcttctttg gctagattct
    14161 ttttgataag aaagttttgc gcataccctg ttggtacttc cttaatttcg ccttttttac
    14221 cttttccttt aacatctgct aaaaagatta ctttcattct tctttctcct tttcctttat
    14281 ttcatttaat acaatttctg tcagtttttc acctgcttct gacaaggtta catctttaat
    14341 ttgagctgct gccaaattaa agtggcctcc accgcctaac tcttccataa tccgttgtac
    14401 attcagttta ctacgacttc gagctgagat agagataaat ccttgtgtat tcttcgcaag
    14461 aacaaaactc gcttcaatac ctgacatggc taacatggca tctgctgcct tactaataac
    14521 aactgtatca tagcatttcg tgtccttagc ctctgctatt agtacatctg aacctaattt
    14581 acacccctgt aaaataagtt cattaacctc acgatattct tcaaaatctg tcgcagcaat
    14641 ttcctggata gcaatactat cacttccgcg cgttctgaga tagctagcaa catcaaatgt
    14701 ccgactagtt actcgcgagg tgaaattttt agtatccaac atcataccag ccatcaaaac
    14761 acttgcttgc atacgactca aacgattttt cttagaattc tggaactgaa tcaattccgt
    14821 taccaactca ctggcactac ttgcaccact ttcgatataa gtaatgactg cattatctgg
    14881 aaaatcctga tcccttctat ggtggtcaat aacaatggtt tgggtaaata aatcataaaa
    14941 ttcttttgat aatgttaagg ctgtctttga atggtctaca agaatcaaca aagaacgatt
    15001 ggtcaccatc cccattgcat ccttaacaga caacaacttc gtaactcctt ctttttctat
    15061 gaatgaaaca gctcgttcaa tatctggaga catttgttct tcatcataaa gagcatagct
    15121 attttcaatc acattgctgg cgaacaactg catacctaca gcagagccca aagcatccat
    15181 gtctaaattt ttgtgaccga ctacaaaaac ctgatctaca ctccgaatct tatctgaaat
    15241 agctgtcatc atagcgcgcg tacgagtccg tgtacgcttg attgaagcag cagacccacc
    15301 accaaaataa actggatttt tcgtttcgtc gttttcctta acaaccacct ggtcgccacc
    15361 acgtacttca gccaagttca aattgagcaa agcaactttc cctatctcat catgatttcc
    15421 atcgccataa gaaaatccca tacttaaagt caagggcaac tgtctctgtt tcgactcttc
    15481 tctgaaagca tcaataacag aaaatttatc attcatcaag ccctcaagca ccgtgtagtc
    15541 agtaaataga taaaatcgat ccatacttac ccgacgagaa aacatcatgt atttttctga
    15601 aaactctgat ataaaattag ctacaaaact attgatttga ctaatatctg actcagaagt
    15661 tgcatcctcc aaatcatcat aattatccac agagacaatc ccaatcactg gtcgacttgt
    15721 taccaattca tctgttatgg cttgttccct ggatacatct acaaaataca aaacaccgga
    15781 agaagcatcc atatgaacag cataacgctt ctcaccaagc ttggcataag tagacggatt
    15841 tcctactgaa gccttgataa tcgtttgaac agcttctaaa tcaaaatcac catcttcctt
    15901 ggtcaaaatc aattcagcat agggattaaa ccactcaacc tctccagaag ataaattcaa
    15961 tttcataaca cctacaggca tctgttccaa tagagctgtc aaactttctt ccgcttggtg
    16021 gtttacatac tgtatctgtt ctacatcact ccttgtataa tgcactctca gtttcttaaa
    16081 taaaaaaaca tagcctccta caaaaagaaa caaaattaaa accgtcaaca gattattatt
    16141 aacaaaaata atgaaagtgg ataagactcc aaacgcaatc aatcctacta gaataggaaa
    16201 aattggactt acataaaatt ttttcattca aaacctcttg gcacccatta taccataata
    16261 cccctcaaaa agcgactttt taaaagtgta atcagtaatt ctatcaatta taagaaaaag
    16321 gtagtttaca attcagtaaa cctaccttta cacatattga aattaagatt ctttaacctc
    16381 taacaaacca atttcgccat cctcacgacg ataaatcaca ttggttgtct gatcttcaac
    16441 atccacatag ataaagaaat catgccccaa taaatccatt tgtagaattg cttcttccaa
    16501 atccattggt tttaaatcaa tttgttttga acgaacaact ttagactgga caatatttga
    16561 atcttccacc aaagcatctg taaataattg accagttgct accttatttt tatttttacg
    16621 ctcgattttt gttttatttt tacgaatctg acgttcaatt ttatcagtta caaggtcaat
    16681 tgaaccatac atatcttgag atacatcttc tgcgcggaga gtaatagatc caagcggaat
    16741 cgttacttcc actttagccg ttttttcacg ataaactttt aagttaattc gggcatccaa
    16801 ctcttgttct ggttggaagt acttttcgat cttttcgagt ttagaaacta cataatcacg
    16861 aattgcttct gttacttcta ggttttcacc acggatacta tatttaatca tatgagtacc
    16921 ttctttctaa acatttttgt ttttatgatt ttattataac gctttcattc tatttttgca
    16981 aattttttcc tcatcttaca agggaaaatg tttttacatc cttagcaccg gcttcttcca
    17041 acagtttctt aacacgattt atagttgctc ctgtagtata gatatcatct ataagtagga
    17101 tttttttagg aatagtgact ccacttttaa taaagaaagg aagttctgtc cccaagcgct
    17161 ctgaacgatt tttagaagaa ctggctctct cttctctttt ctctaataaa tctagatact
    17221 caaagcctgc tgcctctacc aagccctcaa cctgattaaa tcctctatta gcatatctat
    17281 caggacttag gggaattaca acaaattgat actctttgta ctttttcaac tcctcactta
    17341 aaaatgaagc gaaaactttt cttaacagga agtctccatc aaacttatac cgactgaaaa
    17401 aatccttcat agcttgattg taagtaaaaa tcgctctatg actgactcca actccttctt
    17461 tacaccaaag ttgacaatct tgacactttg ttgacaactc tgttttcata caatttggac
    17521 agttctcttc cccaattctt tcaaaagtag aatcacagtc tgaacaaaga caagagtcat
    17581 cattcctcag aagtaagaga ctactaaaag ttaaaacagt cttcatagtc tgcccacata
    17641 acaagcactt catagaccag cctccttatt catcatctga atttccttaa tcgccttctt
    17701 gattgaagca tttaacccat catggaagaa aagcaaatct cctgtcggtc tatccatgct
    17761 tcgtccaaat cgtccaccaa tctgaatcaa actagacttg gtaaacaaac gatgattggc
    17821 ctctactacg aaaacatcca cacaagggaa ggtaactcca cgctccaaga ttgtcgtact
    17881 gataagtatt gtcagttctc catctcgaaa agcttgtact tgctctaatc gatcctctgt
    17941 tacagaagat acaaagccaa ttttctcatt tggaaattgc tcctgtaaga tttctgctaa
    18001 ctgctcccct ttcttaattt ctgaagcaaa aatgagtaac ggataagctg tctttctctg
    18061 cttctcaata taggacttta actttggtga caaacgattc ttgtctaagt agcgattaaa
    18121 atccgataac caaattggtt ttggaataat caacggattt ccatgaaacc gtctcggtaa
    18181 attcagtctt tttagttctc ctaaacggac ctttttatct aactcattgg tcgaagtcgc
    18241 tgttaaaaag attctcaatc cattctcctt tacactattc ttgacagcgt ggtaaagcat
    18301 gggattatca acataaggaa aagcatctac ttcatccact atcagcaaat caaaagcttg
    18361 ataaaacttc aataactgat gggttgttgc aacaactagt ggtgttcgaa aataaggttc
    18421 cgattctcca tgtagcaaag ctattccgca agaaaaatcc tgttgcaggc gcttgtacag
    18481 ctccaaacaa acatctatgc gaggactagc caaacacact gcaccacccg cattgatcac
    18541 tttagccact acttgataaa tcatttctgt ctttccagct cctgttaccg catgaactaa
    18601 ggttggcttt tgcttgtcta ctgcttgaag cagtccctct gacaccttct cttgaaaagg
    18661 agttaattgg ccgcgccatt tgagaacatc ttgcttcgga aaatcctcct gcggaaaata
    18721 gtataaagtt tgatcacttc tgactcgctt catcagcaag cactctcgac aatagtaagc
    18781 accgatgggc aaataccatt cttctagaat agtactatta caacgttgac agaaaagttt
    18841 ccccttctcc tttctcattg ctggaagttt ctccgccaac tgacgttctt cttctgttaa
    18901 ttcattctca gtaaataaac gaccgagata atctaaattt actttcatac ttctttattc
    18961 gtaaaaacta gcactttaga tgatttttta gtacaattaa atcatggaat ttaggacaat
    19021 taaagaggac ggccaagtcc aagaagaaat caaaaaatct cgctttatct gccatgccaa
    19081 gcgtgtttat agcgaagaag aggctcgtga cttcattact gccatcaaaa aagaacacta
    19141 caaagcgaca cataactgct ctgcctttat tattggagaa cgtagtgaaa ttaaacgtac
    19201 aagtgatgat ggtgagccta gtggtactgc tggtgttccc atgcttgggg tactagaaaa
    19261 tcacaatctc accaatgtct gtgtggtcgt gacacgctac tttggtggta ttaaactagg
    19321 cgctggagga ctaattcgtg cttacgccgg cagtgtcgcc ttagctgtca aagaaattgg
    19381 tattattgaa ataaaagaac aggctggcat tgctattcaa atgtcttatg ctcagtacca
    19441 agagtacagt aacttcctta aagaacatga tctcatggag ctggatacaa actttacaga
    19501 tcaagtcgat acgatgattt atgttgataa agaagaaaaa gaaactatta aagctgcact
    19561 tgtggagttt tttaatggaa aagtcacttt aactgaccaa ggtttacgag aggttgaagt
    19621 tcctgtaaac ttagtgtaaa caatgaataa tacagcgttt cgttgacatt ctcacaacta
    19681 ctttagcgag caaaataaaa agatgcgtac caaaatatac tagaaaatga agcaattcaa
    19741 acgaaacctg atatcgtttt ccttcacacc tatttactag aattaactga acgcaatcac
    19801 ttgaaaatta atgactttga tctatgatat atagaaatcc tatcgcttcg ataggatttc
    19861 tatattttac aaatggtatg gatagcgtta tactaaagat atcttataca aagaggtatt
    19921 catatgtcta tttataacaa cattactgaa ttaatcggtc aaacaccgat tgttaaactt
    19981 aacaacatcg tgccagaagg tgctgcagac gtctatataa agcttgaagc atttaatcct
    20041 ggttcatctg taaaagaccg tattgccctt agcatgattg aaaaagctga acaagatggt
    20101 attctgaaac ttggttctac tattgttgaa gcaacaagtg gaaacaccgg tattggactt
    20161 tcatgggtag gtgctgctaa agggtataaa gtcgtcatcg ttatgcctga aactatgagt
    20221 gtagaacgac gtaaaattat ccaagcttat ggtgctgaac tcgtcctaac tcctggtagc
    20281 gagggaatga aaggtgctat tgctaaggct caagaaatcg ctgctgaacg tgatggtttc
    20341 cttcctcttc aatttgacaa tccagctaat ccagaagtac acgaaagaac aacaggagct
    20401 gagatactag ctgctttcgg taaagatgga ttagatgcct ttgttgctgg agtaggtact
    20461 ggtggaacga tttctggtgt ttctcatgca ctcaaatcag aaaattctaa cattcaagtt
    20521 tttgcagtag aagcagatga atctgctatt ctatctggtg aaaaacctgg tcctcacaaa
    20581 attcaaggta tctcagctgg atttattcct gatacacttg atactaaagc ctatgatggt
    20641 atcgttcgtg taacatcaga tgacgctctt gcactcggac gtgaaattgg tggaaaagaa
    20701 ggcttccttg tagggatttc ctcagctgca gctatctacg gagccatcga ggttgccaaa
    20761 aaattaggta caggtaaaaa agtccttgcc ctagcaccag ataacggtga acgttatctc
    20821 tctacagcac tttatgaatt gtaaccgtcc aataacgaag tctattgaaa aatctccaga
    20881 ctagagaact cacggatagt tcctaatctg gagatttctt atttgcactt ttcttgtaca
    20941 actttagtcc atggtaaata ggcctctaaa acctctttgt ttacgagagt ttccacgttt
    21001 ggaagacatt ctagaagata ggatagatat ttctcactat ttataatgga ttgaaataag
    21061 atatgaacaa atcgattagg acatgatggt aaagcgtaat cccttgtttc tcagctttcc
    21121 cagacaaaaa agtccaatag taagtcagct gactatcact ctctagcacc ctataagaag
    21181 tttcatccgc atgaagtaag ggctgagtca atagtctctc tcgcaagagg ttataaaggg
    21241 gctccaaata gtattgactc gtcttgatat gccgattaga gatttcctta cgtgtgattg
    21301 gtaaacccat cctagcccaa tcttcttctt ggcgataatt gggtaccttc agattaaa
//
LOCUS       DAVBOM010000036        20935 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBOM010000036 DAVBOM010000000
VERSION     DAVBOM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20935
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.036"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..179
                     /locus_tag="VQ878_001443"
     CDS             <1..179
                     /locus_tag="VQ878_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095774.1"
                     /translation="FKRVGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQKLIAYRYKE
                     GKLLFVKKEASDVL"
     gene            169..657
                     /locus_tag="VQ878_001444"
     CDS             169..657
                     /locus_tag="VQ878_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095775.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            657..2534
                     /locus_tag="VQ878_001445"
     CDS             657..2534
                     /locus_tag="VQ878_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET3095776.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            2555..2797
                     /locus_tag="VQ878_001446"
     CDS             2555..2797
                     /locus_tag="VQ878_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095777.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            2814..3668
                     /locus_tag="VQ878_001447"
     CDS             2814..3668
                     /locus_tag="VQ878_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET3095778.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            3722..4081
                     /locus_tag="VQ878_001448"
     CDS             3722..4081
                     /locus_tag="VQ878_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET3095779.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            4032..6389
                     /locus_tag="VQ878_001449"
     CDS             4032..6389
                     /locus_tag="VQ878_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3095780.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEDRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGIFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSDENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            6401..9214
                     /locus_tag="VQ878_001450"
     CDS             6401..9214
                     /locus_tag="VQ878_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3095781.1"
                     /translation="MKDKRKIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKEGRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKAKKE
                     VKDAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQAIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATASSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(9245..9433)
                     /locus_tag="VQ878_001451"
     CDS             complement(9245..9433)
                     /locus_tag="VQ878_001451"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095782.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALMSK
                     ITIRLTMSRLLIYTIYST"
     gene            9452..10018
                     /locus_tag="VQ878_001452"
     CDS             9452..10018
                     /locus_tag="VQ878_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095783.1"
                     /translation="MANSRDYRNPNYTEKIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYQKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIEELLGKHVHLTGSGRYLYLEFDYALRTRKQILALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            10170..10580
                     /locus_tag="VQ878_001453"
     CDS             10170..10580
                     /locus_tag="VQ878_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HET3095784.1"
                     /translation="MEGIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENEQD
                     LEDLYTYYMRTDSISLLSSDLETSPQKVEMEIEL"
     gene            10628..16858
                     /locus_tag="VQ878_001454"
     CDS             10628..16858
                     /locus_tag="VQ878_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3095785.1"
                     /translation="MEVMKLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     VEEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVCHQKQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELKKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYQQLPLT
                     QKLKIITHFDEVKAIREKSKQVAESLSPSSDIEQETEETNSFSNIDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLVRLELFKDSNQLFEENPILYLNSLEEIEQVLSHV
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEENENEKEKEKDKETETLIVGIEETDVPVQD
                     FVFPDDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLAN
                     EFFDELNPKYETERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEG
                     GRILDPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVP
                     YQNNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTM
                     DKRTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVF
                     SGSIPFEEDKRVWINPYFDGKYNTQVLGQYEVRNFNGGTLNVKGVSETLVTEIMKAFE
                     NVEAPKQIDNSLKAPVFIQEEVDNSIPSRICEDLALYSFGYEGNQIYYRDTHGIRKSS
                     KVDEISYYVDEKGEFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGL
                     FKKTVFYESPLSDKDISRIKGMVDLRETYQALIEIQRHPDYSRSDFQILLSKLNRDYD
                     RFVSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPE
                     RVITRVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILMDPESYLRG
                     ERKYLSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFK
                     IGSRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAK
                     DSSLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHL
                     QELFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAI
                     QRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKF
                     FPTKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDK
                     LNELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEA
                     HHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSIS
                     ELYTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLP
                     ELMKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDAVKCGTVD
                     PSQDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMGNKATQMI
                     FSDIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEV
                     RILLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYI
                     TKGSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKY
                     KMELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEISKD
                     QAFSMTVGKQAFDQRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPINQPL
                     PETFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWTTA
                     KVEIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFE
                     LD"
     gene            16933..17217
                     /locus_tag="VQ878_001455"
     CDS             16933..17217
                     /locus_tag="VQ878_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095786.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            17231..17527
                     /locus_tag="VQ878_001456"
     CDS             17231..17527
                     /locus_tag="VQ878_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095787.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASRLFLIGFVSFLIFVE
                     VYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSMNKEKM"
     gene            complement(17541..17738)
                     /locus_tag="VQ878_001457"
     CDS             complement(17541..17738)
                     /locus_tag="VQ878_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095788.1"
                     /translation="MNKLKEENLRRALSHIERHKQAINTTNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            17898..18539
                     /locus_tag="VQ878_001458"
     CDS             17898..18539
                     /locus_tag="VQ878_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3095789.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKVTPKTLEESSSIPSLPNTTTK"
     gene            18549..19634
                     /locus_tag="VQ878_001459"
     CDS             18549..19634
                     /locus_tag="VQ878_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET3095790.1"
                     /translation="MEIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKDALAFLSEEPFQKEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTKCRGISEEIVQKMIQQGLMAQASWKTNETVELVIVFKSFDHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLMSYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLMNTIRDTTT
                     YFDNHPDLLTLAVDCDDAGKDFSDKLFQAGLPVLLDLPDNESGKEKIDWNDILREKKS
                     DLQLILESAKETLRNQPVRQTSQCLEL"
     gene            19685..19918
                     /locus_tag="VQ878_001460"
     CDS             19685..19918
                     /locus_tag="VQ878_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095791.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            19915..20298
                     /locus_tag="VQ878_001461"
     CDS             19915..20298
                     /locus_tag="VQ878_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET3095792.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFRNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIESSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            20336..20608
                     /locus_tag="VQ878_001462"
     CDS             20336..20608
                     /locus_tag="VQ878_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095793.1"
                     /translation="MFTKIFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     EQESEQLKTETTYREETLDDTLKKAKNQLHKEQLEKNLERFRKNSQ"
     gene            20678..>20935
                     /locus_tag="VQ878_001463"
     CDS             20678..>20935
                     /locus_tag="VQ878_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095794.1"
                     /translation="MIGKNIKSLRKTHDLTQHDFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERG"
BASE COUNT         7182 a         3317 c         4301 g         6135 t
ORIGIN      
        1 aatttaaacg tgttggtatc gttgatggga aggcagtaga agtcactctt cgagaacctt
       61 attcgagaga tctactgaag gttgtcaagt cgattaagca acgtcagaaa ttgatagctt
      121 atcgttataa agaaggaaag ctgctatttg tgaagaagga ggcatcagat gtcctctgaa
      181 caacaggaac gaatggcagt tcaatatgca gagcgtagtc ttttatttac tgtaaaaagt
      241 cttttaaaga ttctagaatg gtctagacgt caggctttag cacaggattc cgcctataag
      301 ataggagtgc agaaattaga agaattgcta caatctccct atgcgattga tacgattaat
      361 ctgaaaaaag attttttaga caaaccaatt gatatagaga aatttaaagc ttttttagaa
      421 aaagaagaga ttcctttagc catcgcttgg caaggggatt ctctacattt ctacgcgaaa
      481 gaccgttcga ttttagacaa tcatttagac catcttttag aaaaaatggt taatgatccg
      541 gagaaattag ctgattttac catggataag tcattagatg atgctattga tgaagctaaa
      601 tcccaaatta cctttagaca agaaggagcc gtcaaacaga aagagatggt gagatgatgt
      661 acagtggaaa aaaattccta ctattctcac tgttaggtat cttactaggc tatctttttc
      721 atcgtttgac gcttttgtat gattcctata ctggaaatac cttagataaa tggactcatc
      781 ttctgatgga aggtcaagat gaagttcttc agtcgccatg gaatgtttct tttactggaa
      841 aatcaagtgc tttttttcta ctaggttttg tgatgatgtt actggtttat ctctatctag
      901 agactggtaa aaaacaatac cgagaagggg tagaatacgg gagcgcccgt tttggaactc
      961 taaaagaaaa gaagctcttt tacggtaagg aattttctca tgatacgatc ttagcacaag
     1021 atgttcgttt gacattatta gataaaaaac caccccaata tgatagaaat aagaatattg
     1081 cggtgattgg aggttcagga agtgggaaga catttcgctt tgtgaaaccc aatctgattc
     1141 agatgaatag ttctaatatt gtagtggatc ctaaagatca cttggccgag aaaacaggca
     1201 aactcttttt agaacatggc taccaagtaa aggtgttaga tttagtcaat atgaagaact
     1261 cagatggctt taatcctttt cgctatatag aaacagaaaa cgatttgaat cgcatgctga
     1321 ctgtttattt taataacacc aaaggctctg gctcccgaag tgatccattt tgggatgaag
     1381 cttctatgac tttggttcga gctttagcct cttacttagt cgatttctat aatccaccta
     1441 aaacaagaga acagctcata gaagaaagtc gtttaagtca aaaggaatat caaaacttgt
     1501 tgaaacgtca aaaaaaagaa gtggaagagc gaaaaaaacg aggtcgttat ccaagttttg
     1561 ctgaaatctc aaaactcatt aaacacttat ctaagggtga aaaccaggaa aaaagtgtct
     1621 tagaaattct atttgaaaat tatgctaaaa agtatgggac tgaaaatttt accatgcgaa
     1681 attgggcaga ttttcaaaat tataaggata agactctgga ttctgttata gctgtaacca
     1741 ctgctaaatt tgccctcttc aatattcaaa gtgtcatgga cttgaccaaa agagataccc
     1801 ttgatatgaa gacatggggc aaggaaaaat caatggttta cttagttatc ccagataacg
     1861 atagtacctt tcgctttctt tcagccctct ttttttcaac cgtatttcaa accctaacaa
     1921 gacaagcaga tattgatttt aagggtcaat tgcctcttca tgtgagagtt tacttagatg
     1981 agttcgcaaa tatcggagaa attccagatt ttgctgaaca aacctcaaca gtccgttctc
     2041 gaaatatgag tctcgttcct attcttcaaa atattgccca acttcaaggg ctctataaag
     2101 aaaaagaagc ttggaaaacc attttgggga actgtgatag cttagtctac ttaggtggta
     2161 atgatgaaga tacctttaaa tttatgagtg gcttactcgg taaacaaacc attgatgttc
     2221 gaaatactag tcgttccttt ggccaaacag gttcaggatc cctttctcat caaaagattg
     2281 ctcgtgactt aatgacaccc gatgaggtcg gaaatatgaa acggcatgaa tgcttggttc
     2341 gaattgccaa tatgcctgtc tttaaaagca aaaaatacaa ttccactaag catccaaact
     2401 ggaagtacct agctaatcaa gaaagcgatg aacggtggtg gaactatcaa atcaatcctt
     2461 tgaatcaaag acaagaaaat tatcttgacg accttagaat tcgtgattta acttttgaat
     2521 ctagtttaaa ataaaaatag aaaagaggaa atagatgatt acgcatttta aaggttttgt
     2581 ttatggagta gacgcaagtg ctatgtttgc acaagctatg tctttgttac agaagggatt
     2641 gattgcagtt ggtgcctttc tcgttgttgt ggggattgtc aaccttgcaa ccaacattaa
     2701 agatggtgga ccaggtgttc ggaatgccat tcttgaaatt gtcggtggtg ttatggtagg
     2761 ggctgctgga gcctttgtaa cccagatttc aatttaggag gataaacaat gacatgaatc
     2821 ttagtttagt ctcacccttt gtttaccttg catctgaaaa aatatcagct gaaaatttat
     2881 ttgaaggatt taatgtggat ttacaatcta cggtagatct gattaaatcc ctatctagct
     2941 acaatccaac agtttggact tatatgtcta gtattactaa aagtgtcatg cagcctcttg
     3001 gagttgcgat tttatcagtt gttctcatct tagaattttc gaagatggca aagaagattg
     3061 ctaactctgg tggagcgatg acctttgaag cattagcgcc gatgttgatt agttatatta
     3121 tggtcgcagt ggtcattacc aatactaccg ttatagtaga agctatcatc gggattgcga
     3181 gtcacgccat cgaacaagtg gcctcgattg tggctcacgg tggggcgaag tatgatacac
     3241 tctctggatt aaaaggttca ggatttattg gccggatgat tgtgggcttt ttcgctctcc
     3301 ttatctggct tgttcggata gtaagtgcag ccatggttaa tcttttggta tctattcgat
     3361 ttattcaact ctaccttatg atcccatttg cccctcttac gattccaaca tttttaagtg
     3421 atgaatggaa gtctattggt attggctatt taaaaaatat tatggtctat gcggtacaag
     3481 gggttctcat ttttctgatt gtttctcttg ttcctttgtt tgaatctgct gggaaaatag
     3541 ctgtttcaaa tggtgcagga gtcttgcaat cacttgcgat tatgtttggt agtttagtac
     3601 aagctatctt actgattatt gccctcgttg gttctcaacg tacggctcgc tcaatcttag
     3661 gtatgtaatt agataaaggc taggaagtga ttgcttctta gcctttttag aaaggaaagt
     3721 catgaataca cgtgtcttta aagacatctc aaaataccaa cacagggctt ggttaggttt
     3781 caccacaaga caaatcatct ttgttttacc agcctttatt gtcacaatta ttgttttggg
     3841 cttgaatctc tttttctggc aatttggaga ttggtttgtt tacggttttg tgtttgcttt
     3901 taccatcccc ctaatgcttt ttggagtcta taaacccaat gatttatatt ttgaacatta
     3961 tttgaaatac cgtcttcatt ttgaattaac ggttccccta cgcacaatta caggaaagaa
     4021 aggacctgaa catgaaaaga aaatcaaata cattaaagaa acaaaaaact tcaatgacta
     4081 ataaaaagga agaagttaaa gggaaaaaag aggaagtgtt accctcaacg gctaatactc
     4141 tttcctatca agccctgtat caaaatggtc tgatgcaggt aaaagaagat tatttctcac
     4201 aaagctattt acttggtgat gtcaattacc agaccgttgg tttagaagat aagggcgcaa
     4261 tcattgagaa gtattctgat ttgattaact cactagatga ccaaaccaac ttccaattga
     4321 ctatctttaa taaaagattg aatttagaaa agtttagaca aagtgttttg tatgaggaaa
     4381 aagaagatgg atatgatacc tatcgtaaag aattgaatcg gatgatgaat cagaatttag
     4441 atagtggtga aaataacttt tcggctgtaa aactgattag ctttggaaga aaggattcta
     4501 atcccaaaca agcctatcgt tccttgtctc aaataggaga atatttcaag agtggtttct
     4561 cagaaattga tgctcgattt gaatccttgg ctggagaaga tcgtgtgaac ttgttggccg
     4621 acatgcttag aggagaacac catcttcctt tttcttaccg tgatttaacg agatctggtc
     4681 agacaactcg tcacttcata gcccctaatc tcttggattt taaaaacaag aattacctac
     4741 aaatcaatga ccgcttatta cagattgtct atgtcagaga ctacggcatg gaattagggg
     4801 atcagtttat tcgagacctt atgcaaggag atttggaatt gattgtaagc cttcatgctc
     4861 aaagttcgac caaggcagat gccatgaaga aactacgaac aaagaagacc ttgatggaat
     4921 cccaaaagat tggggaacaa caaaaactag ctcgtacagg tatctatttg gaaaaagtag
     4981 gtcatgtatt agaaagtaat atcgatgaag ctgaagaact tttaaaaacc atgaccgaga
     5041 caggtgataa actgtttcaa acggtcttct tgattgggat ctttggtcag gatgaagaag
     5101 aactcaaaca agctctagat acgattcaac aagtggccgg ctcaaatgac ctaatgattg
     5161 ataaacttcc atatatgcaa gaagcagcct ttaatagttt gctgccattt ggttgtgatt
     5221 ttttagaggg agtatcacgg agtttattaa catctaatgt agcagtgaac tcaccttgga
     5281 cttcagtaga cttacaagac cgcagtggga aatattacgg tatcaatcaa atctcaagca
     5341 atattattac tattgatcga agcttattaa atacaccgtc tggtctgatt ttagggacat
     5401 ctggagctgg gaaagggatg gcaactaagc atgagattat cacgaccaaa atcaaggaat
     5461 ctggtgaaaa tactgaaatt atcatcgtgg atccagaagc agaatacagt gtcattggac
     5521 gagcttttgg gggagaaatg attgatattg cgccagattc ccaaacctat ctcaatgtac
     5581 ttgacttgtc tgatgaaaat atggatgagg atcctgttaa ggtaaaatca gaatttcttt
     5641 tatcctttat cggcaagtta ttggatagga aaatggatgg aagagaaaaa tcgattatcg
     5701 accgagtcac cagactcacc tatcagtcat ttaaagagcc ttctttggaa gaatgggtct
     5761 ttgtcttgag tcaacaacca gaagaagaag cgcagaattt ggcacttgat atggaactgt
     5821 atgtcgaagg ttctcttgat attttttctc ataagaccaa tattcagaca ggatctaact
     5881 tcttaatcta taacgttaaa aagttaggag atgagctgaa acaaatcgct cttatggtag
     5941 tgtttgatca gatatggaat cgtgttgttc ggaaccaaaa attagggaag aagacctgga
     6001 tttattttga tgaaatgcag cttctcttat tagataaata tgccagtgat ttcttcttta
     6061 aattgtggag tcgtgtcaga aaatatggag ctagtccgac tgggataact caaaacgtcg
     6121 aaaccttatt gttagatcca aatggtagac ggattattgc aaatagtgaa tttatgattc
     6181 tcctcaagca agcaaaaaat gaccgagaag aactggttca actcttaggc ttgtcaaaag
     6241 aactcgaaaa ataccttgtc aatccagaaa aaggggcagg actgataaaa gctggttcag
     6301 ttgtcgtacc ctttaaaaat aagattcctc aaggtactca attgtttgat atcatgagta
     6361 cggatcctga taaaatggct tctaattaag gggaagtaga atgaaggata aaagaaaaat
     6421 catacgtgcc cgaaaggcat ttagaagaag cctaaaagat gagaaaaaat tcttgaaaaa
     6481 aggaaagaag gaggtaagga aacagaaaaa agattccgct gtactggatg aaaaagcatg
     6541 gaaaaaagag ataaaagaaa agctagagga gatgagagag gcttcaaagg agagagtaaa
     6601 acaagcaaat gaagactaca atcatattct tcaaaatagt cctccatctc ttttgaatcg
     6661 caaagaatta agagacagac ggttgcctca tgctaggaaa cgattgaaaa tagccaagaa
     6721 gcaatttaga gaagccaagg tagaagcaaa agaagaaaga aaagagggtc gtaaagaaag
     6781 aaaaaccaat caaaaatttc tctacggtca ggaatcgaaa gcaaaatcaa attttttctt
     6841 tcaagggaag agtttagaag aattaaaagc taagaaagaa gtcaaggacg ccaaagaaaa
     6901 tttaaaatct actaaacaag cctataaatc caaaaaggtt agtaggaaag ccaaaacttt
     6961 cctttatgtc cttggacgtg aaggtggaga gttagcttca gaaaatgaag atttagaagg
     7021 ctatcgcaca cttcaagaga ccattagaaa agggaaacgc tacagtcggc tttcttataa
     7081 tcttggaaaa gctagtgtca aaacaggaca agcaacaggt cgttttacca agaaaagact
     7141 gaccaacaca aaagagcgat accatcattt taaggatgga aaaggatgga aactagcgaa
     7201 agataatcca agttccttta aaaatcggta tcgaaaatta aagaaacaag gccttacaag
     7261 tgtacgaaat atctatcaaa aactaaaagc agccttttcc ttctttacat ttgcggctgg
     7321 gaatcctgca acctggatag ttggaggaat agtctttctt cttttactta tgatgagctt
     7381 ctttttagga ttttcatctg ctagtttaat tcaacaagat gaatttgaat taacaaaagc
     7441 ttatacccac ctaacttggg aagacgcaga acatacccga accaatgaca aaggaattac
     7501 ctattacaca aaagttgatg atgtgatggg gtatatgaac tttaaattcc atgactatga
     7561 gttacacaaa ccagttcact tatttagttc agaaacttac aaggattatc tatctacttt
     7621 gtggcatgat ttaaacgatg gggaagattt gaaatccatg caagaccttt atgaaactcc
     7681 taagtataaa ctatcgaaag acgatcaaga ggaaatgaag gaactaaaag aagaaggtgt
     7741 gtatgcttcc atgcaggaat tggacaatcc atttgaaggg aaaagtaacg aagatagttt
     7801 aaccatgact tatcgttatg gatactatga tttagacgga aaacctactc ttcaggagta
     7861 cattctacta gaagctaaag ctcaccaagc aattgtcgca ccaatggatg gagttgtatc
     7921 tctagatggc gacaatgtta ttctcactaa cggaaaagga gaaaacgaga gtcgcttaac
     7981 cttatattcc attcataatg gccgtgcgat tgaggggaca agagtcctaa cgggtgatgt
     8041 tattggtgag acaccagatg atacaggttt gaaagtttcc tatcaaaagt ataagaacaa
     8101 gaaagaaaaa ttggtgtatg ttaatccgca attttatttt ccaaaagtca ttcaacttca
     8161 gacaactatc ttacctgcca ttggtcagtt tggtggggat gagtttgaac gagcgaaaca
     8221 tatttatgag tttttgaaat ctcaaggggc aagtccccaa gccattgcag ctattttagg
     8281 aaattggtcg gtagagtctt ctatcaatcc taaacgagct gagggagatt atttatctcc
     8341 tccagttggc gctaccgctt cctcatggga tgatgaaacc tggttagcga ttggaggtcc
     8401 agccatttat agtggtgctt atcctaatat ccttcataga ggtttggggt taggtcaatg
     8461 gacggatact gcagatggtt caacacgtca tacagcttta ttgaattatg cacatagcaa
     8521 aaataagaag tggtatgatt tagacctcca acttgatttt atgcttcatg gggatagtcc
     8581 ttactatcaa agttggttaa aagatttctt taaaaatacg ggcagtgcag ccaatctcgc
     8641 ccaactcttc ctcacctatt gggagggaaa ttctggtgac aaactactgg aaagacaaac
     8701 cagagcaacg gaatggtatt accaaattga aaaaggcttc agccaaacaa atggaggaca
     8761 ggcaaaaagt gacccacaat cccttgaagg ggttcgtggg gacttgtatg atcattctgt
     8821 tcctggtggt ggagatggta tggcctatgc ctatggacaa tgtacatggg gcgttgcggc
     8881 tcgtatgaac caattaggct taaaattaaa aggaagtaat ggagagaaga tttcaattat
     8941 taataccatg ggaaatggtc aggactgggt tgcgacagct tcaagtcttg gtggggaaac
     9001 tggctctaca ccaagagcag gtgccattgt ttcttttgtg ggaggtacac atggtacacc
     9061 agccatctac ggtcatgtgg cttttgtcga gaaagtatat gatgacggtt ctttccttgt
     9121 gtctgaaacc aactatggtg gcaaccctaa ctataccttt agaaaaatct ctcaagcaga
     9181 tagtgcaata agttttgcct atactacgaa atagaagagt ttacacttga aattttaacc
     9241 attttcaggt agaataaata gtgtagatga gtagtcggct catggtcaat ctgatagtaa
     9301 tcttggacat aagggccaag cggtggcgga caccagaacg aaatccgata gcaatcttgg
     9361 acgtaagggc caagcggtgg cagacaccag aataaaccga ctgactaggt ggcttacaga
     9421 ctctgtaaac cacctttttt gtgaggaaaa tatggcaaat tctagagatt atcgtaatcc
     9481 aaattacacc gaaaaaataa aacttcagcg tttttttact cagttacaaa ttgcggcttc
     9541 tttttttaaa gaacacttcg ttggcaaaat catgtattat gaaacagaaa tagaaagtgt
     9601 tgaacttcat ttttcaccta ctaatttcat gcacctatgt ggtgttgatt accaaaaagg
     9661 tgcaggtagt ttctttgacg attgtttaaa tagacatgtc ataattgatg agttgaaaat
     9721 aaaaaaagat ggaaccacga tgcaaaagtt acaagtttta ggatccattg aggagttatt
     9781 gggaaagcat gttcatctaa ctggttcagg acgttatttg tatttggagt ttgattatgc
     9841 tctacgtaca agaaaacaga tactagcatt aacattgaaa gagacatcaa ggaaaattgt
     9901 tcctcaatct ttattagatt tgaagagaaa gacagtattt ccaaaaggtc aaaaagtaat
     9961 ttcaatttac tcaaaacatt tacaaacgtc ggaacttttt tattatttaa aagattagtt
    10021 tacatatctt ttgtggcata aaatatattt ttatcatttt caggagaacg cagttttggc
    10081 tcgttctctt tttttgttgt gatacttctt tcaaggaata tttggtagga ttggagtgaa
    10141 aaaagattaa ctaggaaaga aggaagtata tggaaggcat ttatcaacgt gattcggatc
    10201 aagatggatt aactgatgct caagaattgg cgctaggaac caatcctctt agcgcagatt
    10261 ctgatggtga tggacgttca gatttagtgg aagtagaaga aggaaccaat cccttagaaa
    10321 aggatttaca agacatagac caaacaagta taactgaacc gtcttcagta tttatggaaa
    10381 tgaaacaaaa gatttcagat atgatggaga gtcactacaa ggaatttata caggctctta
    10441 ttagtattga aacagggatt gaaaacgaac aagacctaga agacttatat acttactaca
    10501 tgagaacaga ttctatttct cttttgtcta gtgatttaga aaccagtcct caaaaggttg
    10561 aaatggagat agagttgtag gggaatcatg tgattctcct attttcgtat agatgaaagg
    10621 agcgagtatg gaagtaatga aattattggc tatgtttcgt ggaacaattc caaaagatag
    10681 ggagaaaatg gacctatttc ttcgctatca ggcgcaacat tttgatgaga aatggcagga
    10741 cttggtagag agttttttgg ttgaagaggg caagatagaa gagatacctc atgtgtattc
    10801 gtttcatcaa gatattattt ctttcctaga ggctagttct gaaaataatg accaagattt
    10861 agaaagttac acaagaaatt ttggacaagc aggtctaagt aaattatctc aattaagtaa
    10921 ttttgagaaa aacttggtgc tagaagtcgc aacctataac ctttccactc gattttatat
    10981 ccaatctgaa aaagagaaac taacaccatt aagtgagctt gtatgtcatc agaaacagga
    11041 tgtcaattta gtcaatgtct atcgggttgc gaataatcta tctgaccgca ttagtagaga
    11101 tatagaggag tttcttctaa tggttgactc aaaagagctt aaaaaagaag ttcttgagat
    11161 tcattttgaa gaaaaagagg gagatgttct agcttatttg ggttcagaat tgatggctac
    11221 tttagatact gttacggatc ttgtccatca tgaagaaaac taccaacaac ttccactgac
    11281 acaaaagctg aagattatta ctcattttga tgaagtaaag gctataagag aaaagtctaa
    11341 gcaagtagcg gaatccttat ctccttcaag tgatattgaa caggaaacgg aagaaacgaa
    11401 ctccttttct aatatcgata aaattgtaga agaagctttg agggaatatc caatcggttc
    11461 acaagtaagt tataaaggac aagtatttca gttggtttcg attgaaaatg cacagttaaa
    11521 tgacttagtt cgcctagagc tattcaaaga ttccaaccag ttatttgaag agaatcctat
    11581 cttatacttg aacagtttgg aagagattga acaagtattg tctcatgtag aacttgaaaa
    11641 agaagattca gagattgaga ttgattcatc aagtgaaagt caggaaatag atttgttttc
    11701 ctacctggaa gaagaaaatg aaaatgaaaa ggaaaaggaa aaggataaag aaacagaaac
    11761 gcttattgta ggcatagaag agacggatgt ccctgttcaa gattttgttt ttccagatga
    11821 tttagaggac ttttatccta agacaaatcg agaaaaaatt gaaacgaata tcgccgcaat
    11881 tgaacttgtt aaaagattag aaaaagaggg acgacaagcg aatccagaag aacaagagct
    11941 actagccaag tatgtcggct ggggtggtct tgccaatgaa tttttcgatg aactcaatcc
    12001 aaagtatgaa acagaacgtt taactcttaa gagtttagta agtaaatcag agtactccac
    12061 tatgaaacaa agttctctca cagcctatta tacagaccca atgattattc gccagatttg
    12121 gcaaaaatta ctggatgatg gttttgaggg aggaaggata ttagatcctt ctatggggac
    12181 tgggaacttc tttgcggcga tgcctagaag tatacgagat aaatcagaac tctatggagt
    12241 tgaattagac agtgtgacag gcgcaatcgc aaaacaactc caccccaata cccatattga
    12301 agtgcgagga tttgaagaag ttccctatca aaataatagt tttgatttag tcttaacgaa
    12361 tgttcctttt ggaaattttc gcattgccga taaaaactat gataaacctt acatgattca
    12421 tgattacttt gtcaaacact cacttgattt agtaagagac ggaggacaag tgtcgattat
    12481 ctcatctata gggacaatgg ataagcggac agataatgtc ttacaagaga ttaaatctaa
    12541 cactcatttt ttagggggag ttcgtttgcc ggatacggct tttaaaaaga ttgcaggtac
    12601 tcgagtgacc acagatcttc tcttctttca aaaggatcaa gcaaagaatc ttaatgagga
    12661 ggaacttgtc tttagtggct ctattccctt tgaagaggat aagcgtgtct ggatcaatcc
    12721 ttattttgat gggaaataca atacacaagt tttgggtcaa tatgaggtgc gtaattttaa
    12781 tggaggaact ctcaatgtta agggggtatc agaaacatta gttactgaaa taatgaaagc
    12841 attcgagaat gtggaagcac ctaaacaaat tgacaattct ttgaaagcac ctgtttttat
    12901 ccaagaagaa gtagataatt ctatcccaag tcgtatatgt gaggacttag cgctctattc
    12961 ttttggatat gagggaaatc aaatttatta ccgagatacg catggcattc ggaaaagttc
    13021 aaaagtagac gaaattagtt attatgtaga cgagaaggga gaatttaaag cctgggacag
    13081 ttctttgtct gaacataaaa tagatcgatt cgtgcaactt catttgacag atgaggaagc
    13141 actagatgta tacaagtcag aagaagcgag taaaagaggg aaatataagg gactgttcaa
    13201 aaaaactgtc ttttatgaaa gtcccttatc ggataaggat attagtcgca ttaagggtat
    13261 ggttgatttg agagagacct atcaagcctt aattgaaatt caacgtcatc cagattatag
    13321 tcggtctgat tttcagatat tacttagtaa actcaatcgt gattatgacc gttttgtaag
    13381 tcaatttgga tacttgaatg cctcagttaa tcggaactta tttgatagtg acgataagta
    13441 ttctttacta gcaagtttag aagatgaata cattgattct aaagatcaga aagtaaaata
    13501 taaaaaatct ttagcctttg agaaagcatt ggttaggccg gagagagtga ttacaagagt
    13561 atcaacggct ttagatgcct taaactctag tttatcggat ggtagagggg ttgatttaga
    13621 ctatatggta tcaatttacc ctgaacatag tcaagctgct attttagatg agttaggtga
    13681 ccagatttta atggatccag aaagctattt aagaggtgaa agaaaatatc tttctaagaa
    13741 ccagttttta tcaggagata ttctcaacaa gatagaagta gttcaactat tagtagagga
    13801 aaacaaccaa gaatatgatt ggaaccatgc tttagatttg ttagaatctg ttcgccctcc
    13861 aaggattcat ctggcagata ttgagtttaa aatagggtca cgttggattc ctcaatccgt
    13921 ttacggtaaa tttgcctttg aatgttttac caatcgtgaa tttgaattgt cttcacctga
    13981 tgttgaacaa gttattgaag tgaatcctgt cgatgggcag gttcatttaa ggacatcatt
    14041 tgcttatcgc tatccaagtg ccaaagatag tagtcttgga gttagtgggt cacgttatga
    14101 tacaggaaga aagatttttg agaatttact taattcgaac caaccgacga ttactatgac
    14161 tgttacggaa ggagaaaaga aaaagaccat cacagatttg gaaaaaacct ctgttctaag
    14221 agcaaaagag cagcatttac aagagctctt tcaagaattt gtctcacggt atccagaagt
    14281 ccaacaagtt attgaggaaa gctataatcg tctttataat cgaacggtaa gtcgagagta
    14341 tgacggtagc catctagtca ttgatggatt ggcacaaaac atcagtcttc gtcctcatca
    14401 agagaatgcc attcaaagaa tcgtagaaga aaaaagagcc ttgttagctc atgaggtagg
    14461 ttcaggaaag accttgacca tgcttggtgc tgggtttaaa ttaaaggagt tggggatggt
    14521 tcataagccc ttgtatgtag taccttctag tttgtctgct caatttggcc aagaaatcat
    14581 gaaatttttc cctactaaaa aagtctttgt gactactaag aaagatttcg ttaaggcaag
    14641 aagaaaacaa tttgtgtcac gtattattac aggagattac gatgccattg tcattgggga
    14701 ttctcaattt gaaaaaatcc ctgtcagtaa ggaaagacag atgaattata tcgaggataa
    14761 actcaatgaa ttacgagaga ttaaaacaca ttctgaaaat aagtatactg ttaaagaagc
    14821 agagcaatca ataagtggtc tagagaaaca attggaagaa ctccaacgct ttaatcgtga
    14881 tagttttatt gattttgaga acttaggaat tgattttctc tttgtggatg aagcacatca
    14941 ctttaaaaat attcgtccaa ttacgggact tgggaatgta gcagggatta ccaatacaac
    15001 ctctaagaag aacgtggata tggaaatgaa ggttcgacag attcaggaag agcatgattt
    15061 taaaaacatt gtctttgcga caggaacacc tgtttccaat tctattagtg agttatatac
    15121 tatgatgaac tatattcaac cagatatctt aaaacgctat caagttgatt attttgactc
    15181 ttgggtaggt gcttttggag aaattcaaaa ctctatggaa ttagctccta caggggataa
    15241 gtatcagcct aagaaacgat ttaaaaagtt tgtcaatcta cctgagttga tgaaaatcta
    15301 taaagaaaca gccgacattc aaacacaaga tatgttggat ttacctgtac cagaagccca
    15361 tattatccct attgagagtg agttaactga aaaccagaaa ctctatttag aagaattggt
    15421 tatgaggtca gatgcggtca aatgtggaac agttgatccg agccaggata acatgttaaa
    15481 gattacgggt gaggcacgga aactagctat tgatatgcgt ttattggact ctagctatag
    15541 tctagcagac aatcataaac tgcttcaggt agttgataat gttgaaagaa tttatcgtga
    15601 gggaatggga aataaggcta ctcagatgat tttttcagat attggaacac ctaagaaaaa
    15661 agataatggc tttgatgttt attctgaaat aaaggcttta ttggttgata gaggaatccc
    15721 tagtaaggaa attgcctttg tacatgatgc caatagtgat gaaaagaaga atagtttgtc
    15781 tcgaaaggtc aatgcaggag aagtgcggat tcttcttgca tcaactgaaa aaggaggaac
    15841 aggtttaaat gttcagagca agatgaaagc agttcatcac ctggatgttc cgtggagacc
    15901 aagtgacatt cagcaacgca atggacggat tatccgacag ggaaatgaaa acaaggaagt
    15961 ggatatttac cactatatta ccaaaggttc gtttgataat tatctatggg caactcagga
    16021 gaacaaactc cgttatatta agcagattat gacttctaag gagccgattc gtgctgcaga
    16081 agacattgat gagcagacca tgacagcttc tgattttaag gcactagcaa caggtaatcc
    16141 ttatctcaaa tataagatgg aactagagaa tgatctaact ctattagaaa atcaaagacg
    16201 cgcctttcaa cgcagcaagg atcactatcg tcatacaatc tcttactgtg aagaaaatat
    16261 gcccattctt gagaaacgat taagcaagta tgaaggcgat attcaacagt ctgaaatatc
    16321 gaaagaccag gcattttcta tgacggtagg taagcaagct tttgatcaac gagctgaagc
    16381 aggtgaatct ctacaccgtc ttatccgtca taatcaagct gacagcaaag aatttcgtac
    16441 cctagcaagc tatcgaggat ttgacattaa aatgcttagt cttccaataa atcaacctct
    16501 tcctgaaacc ttctctgtta agattgtagg agaaaatcag tattctgtca gtttagattt
    16561 gtattctcct ttggggacaa ttcaaaggct tcagcataca attgatcaca ttaaagagga
    16621 ccaagtgaaa actcagaact tattggatga attaaaggat aaatggacta ctgctaaagt
    16681 tgaaattgag aaaaattttc caaaggaaga ggattatcaa actaaaaagg ccgaatacga
    16741 tgtactcgcg ccattgattg aaacagaaac ggatttagat attatagatc aggccttaag
    16801 acaattccac gaaaaaggaa aagaaaagca agaacaactt tcttttgaat tagattaaaa
    16861 aatatatata aatagcggac aagaaaagaa aagcgcggta gaataaagat agaaagaaac
    16921 gaggtaacga ttatgatgga agatacctat tatcaattag aagaggcctt ggtacaggga
    16981 tttcaaacgc ctgaagaata ccaagcctac aaggagctaa aggaacatta tgaggaagtg
    17041 acaggcgatt acagtttttc taaacgagaa ctcactagtc aattggaaat ctctcttcag
    17101 aatcatcgag gtgtggactt tgaagaacat gaaaaagagg agtatttgga cttagttcaa
    17161 aaattagaag agtttgattc ctctcttgcc acccattatc gtcaattgat tgactagaaa
    17221 ggagaaagtc atgaatgatt tactccttat cccagtaatt tttttagcag taggagggat
    17281 tctcattctt ttatggagac tctttcttat tgccagtaga cttttcctga ttggttttgt
    17341 cagttttctt attttcgtag aagtctatgg aatttatctg ttctttactg aacctacttt
    17401 atattttgat gatatcagac aacatggttt aactagtttt acggctgtgt accttttcat
    17461 caatctgatg ttggttctag gattcagttg gcgcttcatt aactccatga ataaggaaaa
    17521 aatgtgaact ttttagatag ttaaaagact ttatctgaat ctaaattcgg ataaggtttt
    17581 ttatttgcct tgattctttc atatacttca tagctaaatt ggagtaataa tttatgaaaa
    17641 tcattatcct cactattatt agttgtattt atggcttgtt tatgtcgttc aatatgagaa
    17701 agagctcttc tcaaattttc ttcttttaat ttgttcatat ttatattata aactgaagac
    17761 agctggtttt gacatttttc tctgaactgt acgattttgc gccagaaatg taggaattac
    17821 ctttcgttgt gatgtgataa aacttacaag ttctttttgt tattcttgac ctagttttta
    17881 tagaaagaag gtctaagatg ttaaataaag tcaaaactaa agccttaatt agtgttggag
    17941 cagtggctgc aactagcttt attctcatga tgggatatac tgctggtcaa cactcaactg
    18001 ctaaacaaag tcgcaaagaa atcgaattgg ctgcagctaa acttgtagag gataaacaag
    18061 cagaagataa agccagcatt ttgtcatcgg atactgtaaa agaatttttg actcagtact
    18121 atacgaaaga aaagctcgga gaaaataata cacgtattca accttatatg actgaatcgg
    18181 catattctca agaattgacc agtcaaaacg atgccatgaa ccaagtgtat aaggactata
    18241 ttttggatta tcattttgaa aaagctgata tctttgttaa tcagactacg aatcaagcta
    18301 ttgccatggt ctcttataat gtaacctatg tatctgattt aaagaatgcc aaccaatcaa
    18361 agactaatca gacagaaaca agaacagtta agttatccta ttctaaacta ccaggtaagt
    18421 tattggtcaa tcaagtgcag gtttggaaat ctgggttaga tgatttagat aaggtaactc
    18481 ctaaaacttt agaagaatca tcatcaatac catcactgcc aaatactacg acaaaatgat
    18541 gatattgcat ggaaatagaa gaatgtaagc aaatttcaat tcttgatgta gccaatcgtt
    18601 taggtatctc ctttaaacaa gtttctagcc gtgtctatga acatcctgaa cacgattcat
    18661 ttcggatttt ttcaactacc aatactttta aatggttttc aagagatatt caaggtgatg
    18721 ttattgattt tgttcgactt gttaagggaa tctcttttaa agatgctcta gcttttcttt
    18781 ctgaagaacc ttttcaaaaa gaagctgttc aagaaaaaag agagagacca ttttattatc
    18841 ctttaaagag agtagaagat tctaactgta gtctggcaag atattactta acaaaatgta
    18901 gaggaatctc agaagaaatc gtacaaaaga tgattcaaca aggtttgatg gcacaagcca
    18961 gttggaaaac aaatgaaact gttgaacttg ttattgtttt taaaagcttt gatcatcgtc
    19021 acaagctgca ggcagcaagc ttacaaggga tttataagaa tcccgctctt tctagagaga
    19081 ggttaaaaac gattctaaaa ggaagccatg gacatattgg aatatccttt gacattggta
    19141 aaccaaatag actggtcttt tgtgaatcgt tcgtcgactt gatgagctat tacgaacttc
    19201 atcaacaaag tctaactgat gttcgtttgg tatctatgga gggattaaaa aggtctgttg
    19261 tcgcttatca aactttacga ctgatagctg aagaaaatca gaagttggaa tttttagata
    19321 cagtaatacc ttcaaagtta ttgcctttga tgaatacaat tcgagataca actacttatt
    19381 ttgataatca tcccgattta ttaacacttg cggtagattg tgatgatgca ggaaaagatt
    19441 tttccgataa gttatttcaa gctggattgc ctgttttact ggatttacct gataacgaat
    19501 ctgggaaaga aaaaatagat tggaatgata tccttagaga aaagaaatca gatttacaat
    19561 tgatacttga gtctgcaaaa gagacattga ggaatcaacc agtaagacaa acctctcaat
    19621 gtttagaatt gtgataacaa aatcaagatg ttttagctaa tattagaatg aaggaggata
    19681 gtatatgacc attattgaac gcttagaaga aaaggtcact aggcaagaaa gtaaggtagc
    19741 aagagagaca gaaaaactag ctgcttacaa agagcaactg gagacagcga tgtttgcgac
    19801 gttcaaaagg cgtcaaagca ttagtcacat gagttttgaa gaagctcttg accatgcctt
    19861 tggtaaagaa agacaattcg atgattctga atttagaaag gatgaaatga gtgaatgaca
    19921 aaagattgga attttaatca accattagaa agtaaatcag aaaatcaaga agatccagat
    19981 aaaattgcgg ctttatttag aaatcatcaa ggaggtaatg atgtaaatta tgaagcagct
    20041 tttcaaaagc gtaaacaagc acctgtgacg gaatcaaatt ctagttctaa acccaaagtt
    20101 acagaggtta gaacaggaaa agagacagat atcactacaa gttatcagca acatcttaaa
    20161 agactgattg cggataacaa tagcgatatt gaaagtagtc aaaagaaaat tgaagagcta
    20221 catacgttga ttgacacaaa gaataaagac aataagaaat tgcagtccat ttatgatgcg
    20281 atttcggaat tacactaagc agtctaaaga ggctgctttt tttgagaggt tatagatgtt
    20341 tacaaaaatt tttaagaaaa atcaagacaa tagtgatata tttaagaagt tgattcatag
    20401 actatctgat atgtctgtcc aagatcttga aaaaattgac agattgttag atatcatttt
    20461 cactccagaa caagaatcag aacaactaaa aacagaaaca acttataggg aagaaacttt
    20521 ggacgacaca ttaaaaaaag ctaaaaatca acttcataag gaacaattgg agaagaattt
    20581 agagagattt aggaaaaata gtcaataacg caccaaaaat ggtgcatttg ctttttctaa
    20641 atgttataat ggtggtatca aataaaagga gtttgccatg attggaaaga acataaaatc
    20701 cttacgtaaa acacatgact taacacaaca cgactttgca cggattgtag gtatttcacg
    20761 aaatagtctg agtcgttatg aaaatggaac gagttcagtc tctaccgaat taatagacat
    20821 catttgtcag aagtttaatg tatcttatgt cgatattgta ggagaagata aaatgctcaa
    20881 tcctgttgaa gattatgaat tgactttgaa aattgaaatt gtgaaagaaa gaggt
//
LOCUS       DAVBOM010000037        20670 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBOM010000037 DAVBOM010000000
VERSION     DAVBOM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.037"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(2..1681)
                     /locus_tag="VQ878_001464"
     CDS             complement(2..1681)
                     /locus_tag="VQ878_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3095795.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     ICTGDFKFDFTPVGEPADLHRMAALGEDGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1683..1916)
                     /locus_tag="VQ878_001465"
     CDS             complement(1683..1916)
                     /locus_tag="VQ878_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET3095796.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFKITEF"
     gene            complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ878_001466"
     CDS             complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ878_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET3095797.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ878_001467"
     CDS             complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ878_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET3095798.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ878_001468"
     CDS             3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ878_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET3095799.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3919..4356
                     /gene="rimI"
                     /locus_tag="VQ878_001469"
     CDS             3919..4356
                     /gene="rimI"
                     /locus_tag="VQ878_001469"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET3095800.1"
                     /translation="MIEIKRIQKHPDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQSQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ878_001470"
     CDS             4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ878_001470"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET3095801.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5396..6702)
                     /locus_tag="VQ878_001471"
                     /pseudo
     CDS             complement(5396..6702)
                     /locus_tag="VQ878_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7036..7330)
                     /locus_tag="VQ878_001472"
                     /pseudo
     CDS             complement(7036..7330)
                     /locus_tag="VQ878_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7437..7730)
                     /locus_tag="VQ878_001473"
                     /pseudo
     CDS             complement(7437..7730)
                     /locus_tag="VQ878_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            7973..9177
                     /locus_tag="VQ878_001474"
                     /pseudo
     CDS             7973..9177
                     /locus_tag="VQ878_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9170..10046
                     /locus_tag="VQ878_001475"
                     /pseudo
     CDS             9170..10046
                     /locus_tag="VQ878_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            10133..11749
                     /locus_tag="VQ878_001476"
     CDS             10133..11749
                     /locus_tag="VQ878_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095802.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            11769..12612
                     /locus_tag="VQ878_001477"
                     /pseudo
     CDS             11769..12612
                     /locus_tag="VQ878_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12680..14181
                     /locus_tag="VQ878_001478"
                     /pseudo
     CDS             12680..14181
                     /locus_tag="VQ878_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            14193..14942
                     /locus_tag="VQ878_001479"
     CDS             14193..14942
                     /locus_tag="VQ878_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET3095803.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            14955..16127
                     /locus_tag="VQ878_001480"
     CDS             14955..16127
                     /locus_tag="VQ878_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3095804.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD"
     gene            16522..17385
                     /locus_tag="VQ878_001481"
     CDS             16522..17385
                     /locus_tag="VQ878_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3095805.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            17671..17904
                     /locus_tag="VQ878_001482"
     CDS             17671..17904
                     /locus_tag="VQ878_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095806.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            17926..18603
                     /locus_tag="VQ878_001483"
     CDS             17926..18603
                     /locus_tag="VQ878_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3095807.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            18615..19280
                     /locus_tag="VQ878_001484"
     CDS             18615..19280
                     /locus_tag="VQ878_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3095808.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            19352..20578
                     /locus_tag="VQ878_001485"
     CDS             19352..20578
                     /locus_tag="VQ878_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3095809.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SAPIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         6467 a         3225 c         4172 g         6806 t
ORIGIN      
        1 attattcttc atctggtgtg aggatcatcg ggatgatgat cggttcacgt tcggtatttt
       61 catagaggaa ggggcgaata gcgttgacaa tggcaccatt gacagattgc acgctagcat
      121 ccttattttt cagtgcgata cgaatggcat tgaagaggat acgctggctt tggcgaatca
      181 agtcgccaga ctctctcatg tagacaaagc ctcggctgag gatgtctgga ccagatagaa
      241 tcatctgcga tttgaagtca acagttgcga ctgccagaac gacaccgtct tcagatagat
      301 cgcgacgatc tttgaggaca gctgcgccaa tttcaccgat acgatttcca tcgacataga
      361 tatcttgggc gttgaaatga cctgcgatac gagctgagtc agcagtaagg gcaagcacat
      421 cgccattgct catgataaag atattgtcct tctcaacacc agtatccact gctagtccag
      481 cgtggacttt ttgcatgcgg tattcaccgt ggacaggcat gaagtatttt ggcttaatca
      541 agcggagcat gagtttttgc tcttgctgac caccgtgtcc agatgtatgg atattgttca
      601 ctttaccgtg gataacttcg acaccagctt cagaaataat gttaatcagc ttgttgacgc
      661 tagtagtgtt tccagggatg ggactagaag agaagataac ggtatcgcct ggttggagtt
      721 gtacctgacg gtgggttccg ttggcgatac gagagagggc tgccataggt tcaccttgac
      781 tacctgtaca gaggatcaga atctcacctg caggatagtc tttgatttca tttggctcaa
      841 taaaggttcc cttaggagct ttgatgtagc caagatcgat tccgttgaca atggcctttt
      901 ccatagagcg accaaagacc gcaatcttgc gcccagtctt aacagcagct tccgttgctt
      961 gttggagacg gaagatattt gaggcgaagg atgcaaagat gatacgtccc tcgatacctt
     1021 ggataatctt catgatggac tggccgacaa ccttttcaga gttggtaaag gttggaacct
     1081 cagcattggt cgagtcagag agcaagcaaa gcactccatc ttcacctagg gctgccatac
     1141 ggtgcaagtc cgcaggttct ccaactggag taaagtcgaa cttaaagtca cctgtacaga
     1201 tgattttccc ttgaggagta tggatgacaa ttcccaaagg ttctggaata gagtgagtcg
     1261 ttctaaagaa agttgccttg agatttttaa aggtcaactc ggtgttgtgg ttgatttcgt
     1321 aaagtttggc gttgcgcaag aggccgtgtt cttcgagttt cccacggatc aaagccaagg
     1381 caagcggtcc agcataaata gggacatttg cttgcttgag taggaacgga atcccaccaa
     1441 tgtggtcctc gtgtccgtgt gtgattaaaa cagccttgac gcggtcgata ttgtctacga
     1501 tgtaagagta gtcaggaatg acatagtcga taccaagcaa gtcatcttct gggaatttaa
     1561 tcccagcatc gacgatgata atctcgtctt ggtattcaat tccgtaagtg tttttcccga
     1621 tttctcctag accaccgatg gcaaaaacgc cgacttcttc aggtttaaga gtgtaggcca
     1681 tattagaact ccgtaatttt gaaggcgcca gtttcttttt cgtaatcgag caatttgtca
     1741 gacaagagtt cgatatattc gatattgtac tctgggcgat tttcttcgac aagttggcga
     1801 gcagcgatac gaccctcaag ttctgagctg gcatcgatgt ctaggtaaag cgcgcgtgtt
     1861 gtttcacgac gtgggctacg ttcttttgtt tcttgataaa aaactttgta aatcatatag
     1921 ttcctttcta tttacaggtc agcttattcc aaacttttag cagagatttg cttgatttca
     1981 ttccattttg tgtctagatt gaccttgatt cgttacaatt atttcaatta taccacaaaa
     2041 tgaaaaatta gtaaaagacg gaaacgagaa agttagggga cgatttcttt ggtaagcgtt
     2101 tgcaaaaaca aagaaaatgt attatgttga taacggaagt gaaatttatt gcttgtcata
     2161 attccatata gattttaagt caaggaggtt gccctatgta taacttattt gcttttgcta
     2221 tcggagttcg tttgctagct tttatcgttt ttgttgcttg cgtttatgga ggaaatcttc
     2281 tatttgccaa actggaacga tgacaaacca agttcttgag gaaaattacc tttgtgactc
     2341 tctactcgct ttttctcctc ctcgtgacct atgtcgtttg gtttgtattt tactttggat
     2401 tgccctgctt atgctggggt tttttgtttg gggatgtaga gatagtagat ttacgacacg
     2461 aaaattccac cccatctatc aagatgaggt ggtctttgca tttttctaac atgacatgac
     2521 aatggaattt tcaaagctta ttatttttat gggagtcatt gttctgctca aaaatagagt
     2581 tgaagcataa aaataaaaca atacaaacag ataaatcgaa tggtaaaggg atagtagtaa
     2641 tgttcaaatc attgagaatg ctgagcaaac tgtaagagat gaagacaata aaatttatcc
     2701 ttctaaaaat gtgtttctta tctagcatga cttaccaaac tttttacgaa ggtcttttcc
     2761 aatggtataa cctgccataa ataaagcgat accaacacct acaccaaagc cacccttgat
     2821 ttcttgcaat tccttattag aaatttcacg atagttgttc aaatttttca tcatattaat
     2881 ctcctcctaa aaaataacca gctgccaaac cagaacctat aagtgctgtt ccacctgcaa
     2941 tagctttcca agatactgct actccaaaga taaccaaggg agcgagaccg ccatcaatat
     3001 ctgataattc attttcagat aaggataaaa attgattgtc aagaatgtca aaatttgtca
     3061 ttgaattttc ctcctttttt cttgttcact tttatattcg gaaaagaaaa ggaaaagtga
     3121 gcattttttt aaattatttt tagttaagtg agggcactct tgtctggggg caaagaaaat
     3181 tcccatgtgc cagcttttgt agtataatag taagcagaca aaaagatagg aatgtgttat
     3241 gaaagtatta gcttttgata cgtccagcaa ggctctttct ctcgctattt tagaggataa
     3301 gcagattctt gccgagatga cgattaatat taagaaaaat cacagtatta ccctcatgcc
     3361 tgccatcgat tttttgatgg caagtttgga ctggacaccc aaggatttgg accgaatcgt
     3421 ggtggctgaa gggccaggta gctacacagg cttgcgaatt gcggtagcca ctgccaagac
     3481 tttggctcat actctgaaca tcgagttagt tggtatgtct agcctcttgg ctctggtacc
     3541 ctaccaacaa gaaggcttgt tcgtctcttt gatggatgcg cgtcgcaaca atgtttatgc
     3601 aggattttat gaaaatgcta aacccgtcat gccagaagct cacttaccct ttgagcgagt
     3661 gattgagtta atcaagggtg ctagtcaggt tacctttgtc ggagaagttg gcccctttgt
     3721 tgagcagatt caagaatact tgccaaggac taatttcaaa gaaaccttgc caaatgcagc
     3781 taatctagct ctatgggcct gggacaagga agcagactcc ttgcatgatt ttgtgccgaa
     3841 ctacctcaag cgtgtcgaag ctgaggaaaa ctggctcaag aatcacaccg agtctggcga
     3901 gtcttacatt aaacgcttat gatagaaatc aaacgaatcc aaaaacatcc tgacttggct
     3961 caagccatct acgctgttat gatagctgtt tacccagtca gtccttggac gctggaacaa
     4021 atccaagcag acctgtccca agaccagact tggtatgctt tggcttatga tggggcagaa
     4081 gtgattggat ttctagctgt gcaggagaat ctttttgaag cagaagtcct gcaaatcgct
     4141 gtcaaaggag cttatcagag tcaggggatt gcgtcagcct tgtttgctca attgccgaca
     4201 gacaaggaaa ttttcctcga agtcagacag tcaaatcaac gagcgcaagc attttacaag
     4261 aaagaaaaga tggcagttat cgctgagcga aaggcctact accatgaccc agtcgaggac
     4321 gccattatca tgaagagaga aatagatgaa ggatagatat attttagcat ttgagacatc
     4381 ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat gagctcttgt ccaatgtcat
     4441 tgctagtcaa attgagagtc acaaacgttt tggtggcgta gtgcccgaag tagccagtcg
     4501 tcaccatgtc gaggtcatta cagcctgtat cgaggaggca ttggcagaag cagggattac
     4561 cgaagaggac gtgacagctg ttgcggttac ctacggacca ggcttggtcg gagccttgct
     4621 agttggtttg tcagctgcca aggcctttgc ttgggctcac ggacttccac tgattcctgt
     4681 taatcacatg gctgggcacc tcatggcagc tcagagtgtg gagcctttgg agtttccctt
     4741 gctagccctt ttagtcagtg gtgggcacac agagttggtc tatgtttctg aggctggcga
     4801 ttacaagatt gttggggaga cacgagacga tgcagttggg gaggcttatg acaaggtcgg
     4861 tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt gacgatctgg ctcatcaggg
     4921 gcaggatatt tatgatttcc cccgtgccat gattaaggaa gataatctgg agttctcctt
     4981 ctcaggtttg aaatctgcct ttatcaatct tcatcacaat gccgagcaaa agggagaaag
     5041 cctgtctaca gaagatttgt gtgcttcctt ccaagcagca gttatggaca ttctcatggc
     5101 aaaaactaag aaggctttgg agaaatatcc tgttaaaacc ctagttgtgg caggtggtgt
     5161 ggcagccaat aaaggtctca gagaacgcct agcagccgaa atcacagatg tcaaggttat
     5221 catcccccct ctgcgactct gcggagacaa tgcaggtatg attgcctatg ccagcgtcag
     5281 cgagtggaac aaagaaaact tcgcaggctg ggacctcaat gccaaaccaa gtcttgcctt
     5341 tgataccatg gaataaagag tggctctttg tcaagtgtag tgggtaggcg aaaagctaca
     5401 atctggagag tacgaaattc gtactctctt ttttgatgtt caaagtcatc aaaatccgtt
     5461 ttttaaaatt gttaaagttc cggaaaccaa aggctttgcg cttgataacc ttaatcaaat
     5521 tattggtcgc ttcaagttta gcgttggaat aaggcagctt aagtgcgttg ataatcttat
     5581 ctctatccct taaaaaagtc caaaagaccg tttgaaaaag cggatgaacc gttggcagtt
     5641 cttgctcaat caatccaaag aaatggtcgg cattcttctc ttgaaaatga aagagcagga
     5701 gttgatagag ttcgtagtga acctgtaatc cctcagagta agaaagcagc ttatctcgta
     5761 cttcccgatg ggttaagtgc attcgaaacg tgggctgata gaatcgtttc tgacagagct
     5821 tgaagctatc ctggtgtagt aaatcagtcc agtggactga tttagcccga gcctagaaac
     5881 gaaaaagcga gggttccaaa agcgcttgag cgcccgatac tccaaggatt ttcggtcaaa
     5941 ttggttcatg atttggattc gtactcggtt catagctcgg ctcagatgtt ggacaatgtg
     6001 gaagcggtca agaacaatct tcgcctttgg aaagagttgc ttagcgagcc gataataagg
     6061 gctgtacatg tccatggtga tgacctcgac cagctcccga acctctctct gatagcgttg
     6121 gaaatggttt cgaatcaccg catgagttcg tccgtctaaa attgcgagga tggatttgga
     6181 ctcaaaatct tgggcaatga agctcatttt gctctttttg aagctatact catcccaact
     6241 cataactttt ggcaacttgg tccaatcggt ttcaaactta aattccctca gttttcggat
     6301 gacggtggaa gttgagcccg ccaatctgtg ggcaatctca gtcatagact gcttttcaag
     6361 gaggagctga gcgatttttt gtctcaccat gttggaaatc tggcaatttt tcttgacaat
     6421 ggatgtttga gaaacgacca ccttaaggca attcttgcac tgaaagcggc gctttttgag
     6481 atgcagtacc gtgggtaaac cctgacagtc gagaagcgga attttagagg ctttctggaa
     6541 gtcgtatttg atcatcttcc cttgacaatg aggacaagga ggagcggggg aatccaactt
     6601 tgcctgaacg actagatggg tttggtattt cagaacagac aagattttga tatttttgtc
     6661 ttccaatccg agcaaatctg tggtattctt aagttgttcc atatgaaccc tttctaatga
     6721 gttggttaga cgcttttcat tataggtcat atggggcttt ttttctacaa gaaacgaccc
     6781 tataattcct ggggtgggat tacccactac agaaattata gagccaaagc attccaaagt
     6841 cttgtctgac tctggaatgt tttctgttca cagttgtttt gtaactgcct aataagtaac
     6901 cgcgctataa cgaggtatct accgagattg tcaattctcc agtatactgt tataaaaaac
     6961 aaaactggag gattttttta tgtccccccc atcgtcccat cgactgttcc gtagctgccc
     7021 aataacggag tataatcagc tgaaacaaga ataggacaaa agtgcctcaa gaaaagcatc
     7081 gtaatttgac aatattattc tgagatgttt ttgatgtaag cccatatttt ctcaatggga
     7141 ttatactcgg gtgaataggt aggaagtggt aacagtctat gccctgctcc ttacacatgt
     7201 tcattctgtg aaaccttgca ttgtccataa tgataaggga tggtgtatct aaagtaggta
     7261 gtaagaattt ttggaagcaa gcttcgaaaa agtcactcgt catcgtatct ttataggtca
     7321 tcggagccat agtatattga aacaaaaaag ggcattagta cttctataac agtatcgcaa
     7381 tctctggtgt gcgttgtctc gatcttaatt caaataatta tatcttcttc cagagagact
     7441 aactgcctgc tcaaggctcg atcatattcg agataaaaat aggtctcaac ccctgtctca
     7501 taaatataaa taggagtcag gtagcttaag tgattcaatt ctttaaggaa ccgatttact
     7561 ttttctgggt cttgttcgca gtaggtacgg ctctttttta gactatatcc catagccttt
     7621 agagcgtaat gaatagttgt tggaggacag ttgaattcag cagctatttc agtcaaataa
     7681 gcatcgggat gagtttcaat atagattttt aatttatctc tatcaatttt ttcaattaat
     7741 agtggaagtt tttttgaagt tagtgtattg aaacgttttt atacagtgct aaaatttgaa
     7801 gtgtagtgca gatgtatttg taatagtatt atagcaattc tttggagaag gtcgagacaa
     7861 gataaaatag gtatctttga gatataagca tgatttacta taaaattatt gagttattca
     7921 taaaaatttc tctatcaaat atcataatgc gtcgtttaag gagatggtta caatgcaata
     7981 tagttgtgga aaaataaata ttaatatccc tgatggatat ggagacatta aggatatagt
     8041 gttttcggct catattatag ttaggtataa taatggacat tgtggaggta tagatccgca
     8101 tataattgga ctttgtaaaa agcagatcag aaggatgtct ctatatccta ttttgataat
     8161 cgtatctaga gattcaaagg ttattgatga ttataaaaat ttagatattg cctatgttga
     8221 ttgtactcaa tgttcaaata attttgaaac tgccttacac gttaaaaata ttttaaaatt
     8281 attaaaaatc caacttatac actgtcatgg ctactcaact aattattttt tatatatgtt
     8341 aaaaaaactt gacaagaatg gatttggaaa ggttaagaca gtgataacat gccatggatg
     8401 ggttgaatat aacttaaaaa agaaattctt gacttatttt gatttttgga catattctat
     8461 gggagatgct tttatttgtg tatctgaaac tatgaaaaaa agattggaga gtataataaa
     8521 aaaataagaa gatagttgca ataaataacg gaattaatgt atcaaatagc gatttagatg
     8581 tagtaggtgt tcaagacttt aaaaaagaat tttgtattcc aaataacaaa aaatcatttg
     8641 ttatgttgga aggttggatc cagaaaaaag gccggataga ttccttgaat ttgcagaaaa
     8701 attattttta gtcagagaag atgtgatttt tattatggct ggaaatggta gtatgtgggc
     8761 tgctttgaaa gaaaaaattt gctatttgaa atgtagagat aatttcaggt tacttggtga
     8821 aatctatcca gtactatagt ttaccaaata tcggatttat tgtatattcc ttctgataca
     8881 gaaggaatat ctatgtgtgt tttagagtca atgtcacaag gaactccggt tttagctagt
     8941 aatgttggcg ggttaagtga aattattgaa catagggttg atggattttt atttgagaag
     9001 gaagatgttg agggagtgtg tgcttgtgct aattttttac tcaatgattc tgagtatttg
     9061 aaatatgtag gtgagaatag taaatcaaaa ataagaaaac atttttctgt gcaaaaaatg
     9121 tttgtagaaa ccatgagagt atatgatgaa ttattagaga agagtagtca tggataggaa
     9181 tatagatcaa gaattagtaa gtattataat accaacacat aataggtatg aatctctgat
     9241 tagagctgtg aaaagttgtt tacatcaaag ttataaaaat atcgaagtta taattattga
     9301 tgataattat agtaatgtaa atttaagaaa taaaattatc catcaatttg gctataccaa
     9361 tcatagaatt aagttaattt taagtaatga agatttaggt gcaactaatg ccagaaacat
     9421 aggtatcaaa aattctagag gtaagtatat atcattttta gacgatgatg atgaatatat
     9481 gccagatcga attttaaagt tgatggcttg ttttaaaaag agtagaatga agaatttagc
     9541 tttagtttat agttatggaa taataattta tccaaatggt acacgagaag aggagaagac
     9601 cgattttgtt ggaaatccct tgtttgttca aatggttcac aatatagcag gtacgtcatt
     9661 ttggttgtgt aaaaaagagg tgctagaatt aattaatggt tttgagaaaa tagattcaca
     9721 tcaggacggt gttgttttat taaaactact tgctcaagga taccaaattg atatagtgcg
     9781 agaattcttg gtgaattact acgctcacag taaagaaaac ggtatcactg gagtgacaca
     9841 aaaaacaatt aatgcagatg aagaatatta taattactgt aggaaatatt ttaatttatt
     9901 gagtttcaac gagagaatat tggttacaaa gaaatattat tctttaaaca taaagcggtt
     9961 actatttaat aggagacaaa tgcaaggctt taaaagtaat caagaaggca agagaagaaa
    10021 aaatttttaa cgaatttctt ttttaaaata tatgttatta tatcattttg gttttttcta
    10081 ttgtatatat gacaactatg ttcaattaaa atttagaaag tgagaaacta ttgtgtatac
    10141 tattataaaa tcaaatataa aaaaatttag tttattaacg atatttattg ttgctggtca
    10201 attattgcta atttatgcag caactattaa tgctctggtg ttgaatgaat taattgcgat
    10261 gaatttagag cggtttttga aattgtcaat ctaccaaatg attgtctggt gtgggataat
    10321 attccttgac tgggtagtga aaaattatca ggttgaagtg atccaagagt ttaatctaga
    10381 gattcgaaat agagttgcca cagacatctc taactctacc tatcaagaat ttcatagtaa
    10441 atcatcagga acatatcttt cgtggctaaa taatgatgtt cagactttaa atgatcaggc
    10501 ttttaaacaa ctttttttag taataaaagg aatttctggt actatatttg cagttgtgac
    10561 tcttaatcac tatcattggt cattgactgt agccaccttg ttttcattaa tgattatgct
    10621 acttgtacca aaaatctttg catcgaaaat gcgagaagtt agtctaaatt taactaacca
    10681 aaatgaagct tttttaaaat ctagtgagac tatattgaat ggatttgatg tgttagcgtc
    10741 cttgaatctt ttatatgtat tgcctaagaa aattaaagaa gcaggaattt tattaaagat
    10801 ggttatacaa agaaagacaa ctgtagaaac gttagcaggc gctattagct tctttctcaa
    10861 tatttttttt cagatatctc tcgttttttt aacaggctat cttgcaataa aaggaatagt
    10921 gaaaattggt actattgaag caataggagc actaacaggt gttattttta cagcgctagg
    10981 tgaattagga ggtcaattat cctctattat tggtacgaag cctatttttt taaaattgta
    11041 ttcaattaat ccaattgagt caaataaaat gaatgatatc gaaccaaatg aggtgaatag
    11101 agattttccg ttatatgaag caaaaaatat ttgctataag tatggagata aagaaatatt
    11161 aaaaaactta aatttttgtt ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg
    11221 aagcgggaaa tctacattat taaaattatt gaatggcttt ttgagagatt atagtggaga
    11281 attgcgattc tgcggggatg atataaaaaa aacctcctat ttaaatatgg tttcgaatgt
    11341 tctatatgta gatcaaaaag cttatttgtt tgaaggtacg attagagata atattttatt
    11401 ggaagaaaat tatactgatg aagaaatact acagtcttta gagcaagttg gtttgagtgt
    11461 aaaagatttt cctaataaca ttttagatta ttatgttggt gatgatggga gattactgtc
    11521 aggagggcag aaacaaaaaa ttactttagc tagagggcta attagaaata agaaaatagt
    11581 attaattgac gagggaactt ctgctatcga taggagaact tcgttagcga ttgaacgtaa
    11641 gatattagat agagaggatt tgactgtcat tattgttacc catgctccgc atccggaact
    11701 taaacaatat tttactaaga tatatcaatt tccaaaggat tttatttaag aatatagggg
    11761 agggaaacat gagattctat tgtgaagctt atgaggtaat tactgaagag aaaaaagtat
    11821 actttaatga tattgagtta gaagttaagt attcctctgt cgaagaattg tttataatat
    11881 gtgagaaatt attagataag aaaaaagtat cattttttta tgtatatgag aaacccttaa
    11941 ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaata tcccaatctt
    12001 agatggagtt tccaataagc aagttgatcc aacgttgctg catcactttt ctttggaaat
    12061 tgaaaagaat tttatcgatt tttgctataa aaatatggat ctcatcctaa aaactcaaag
    12121 tatatctttg tgtcatagag aagagcttat tattgtagat gtttcagatg actctaaatt
    12181 tggtgttttt tacaagcgtt ttagaacact ggttgataaa aataacggaa aatatgtttg
    12241 tgtttataat ttcagtcgtg tttcagatat actgcaaaac tggaaaaatt attgcaatcg
    12301 aaaattttcg gttacgttta ctgaaagcca atttgaatta tttaagcttt tatataatca
    12361 aaaaaatttt aaaacaattt cgttgctatt tggaaaaaaa ttgttgctgg aggaattatc
    12421 tattatagcg atcttactaa tatagaatac ttttgtattt tttggtggga tagtatgttt
    12481 gggaaagatt ctattggaaa atacgtatat gtagaagaga ttagtagatg tcatttttta
    12541 gatagaaatt attctttttg ttatggttta caagattata aaagtaaact tattaaatat
    12601 tttttagaat agttaatcta ttcgagagag ataaagaaat atggaaaata ctttattgaa
    12661 tatcacagga agcttcgata tggaaactag gaatctaatt agttattctt taactgatat
    12721 ctttgaaaca gataaaataa gaattgaact tcttggagaa atttattata aaaatataaa
    12781 gttggaattg catgaattcg ctggattgta taagatttat ggaattagct taataaagaa
    12841 tattaccgga atgtttttaa ttataatttt tgatacgaag acaaaagaat taaaaatttt
    12901 tcaagatata acgacttcat actttaattt atactatact gtttatggag gtgtgttcta
    12961 tatatagtac atctttaaag aaagtgatga agttatctca tgttcccgtt accttaaata
    13021 acaaaaaaat acaagaattt atgagaaatg gatttatttt agattcaaat actttagtaa
    13081 ccgaaattaa taaattagaa tatttctctt acatttctgt aaataatact cttcgtatat
    13141 gtggtattga ttataatgat tcaaacaatt ttactaaaga acaagtatta aagaattggg
    13201 actctatgct acgtgaatct atattaagag tgtatagtga agcaggagag gctaatatta
    13261 cactatcatc tggttttgat tcaaattata tattatatac attagcgaat tatacgaatt
    13321 cttcaattaa tgcattttgc ataggaggag aaaaaggaat taatgagatt cctgaagtaa
    13381 ctaaaattgc aaaattttat ggtataaatt tattagttga tactgtaatg agcccaagat
    13441 ttagaatatt ttcccgatat agtatggaga ttggaaggaa gtctctttga atgtggtgtc
    13501 atactgcagt actatttagg caggttgttg ttccaaaaag ggaacacaag tattctttgt
    13561 ggcgagtcag cggatgaaat aatgactttt aagtatcatt ctgtgaacta caatcaattt
    13621 tgtaatgata aacagaagtc agtatatttt agttattccg actatccatt ttatgttaca
    13681 aattcaattg ttttaaagaa aaatagccta cttttgcata gttttggcat tcatcctaga
    13741 tatccatata aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat
    13801 aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac
    13861 ataaatagtg tcccgggtac aactcattta tttagttgtt taaatattca aacattagta
    13921 aaaattattt tatatatttt tcgatacaac agttgtatga aaatatttaa ttttagagat
    13981 aaagagctta tcttttttaa taagattgta aatgggctga tacaaaatat tgaggagaat
    14041 ttagaggatg atattgaaag gatattgaaa tatttatata tatgtttatt taacgaaata
    14101 ttcattatta agaataaggt gaattttttt gatgatgtgg aatttaatca gacacttagt
    14161 gagtttttag ataaattgta gagggaatgg ttatgagtga caatactaag tatatctttt
    14221 tatctccaca tttagatgac gcaatttttt cctgtggtga ttatatttca aaattaactt
    14281 cagaaggaga aattgtactt gttattacta tattttctgg ttaccctttg agccaacagc
    14341 tacagccctc tgctaagcaa tttcataagt tgtgtaacct tgggaaatat ccgattgaag
    14401 aaaggaagaa agaagacagg ttagcttgtg aacgtctaca atgtgatttt agacacttat
    14461 cgtactatga atgtctctat aggaaagata gaaatggcaa ttttctatac cgtcatatct
    14521 atagtaaatt aaaaaatgag gacacattaa agaatgatat cataaaagag ctgttaatgc
    14581 atttagacga caaatgtgtc gtatattgtc cgctttcact tggtgaccat gttgatcatg
    14641 tttttgtgaa tagtattgga agggcgcttg aatttatgcg ttataaagta atatattatg
    14701 aggacttccc atatgtaagt gatagtagta tggttagtta tatgggaaaa actaaagaat
    14761 taaaaatgta tcaagaggaa cttgatgaaa aacattatat tgatagaata tcatcaatat
    14821 tgtgctataa atctcagatt ttgataatct ggaaatcagt tgaaaaactt ttaaacaata
    14881 ttaaagagtt gtatttaagg aatggggcag cttattctat tagattttgg attaagaaat
    14941 aaggaagtag ttttatgaat atagcagtaa ttggtttggg gcatgttggg ctggcctacg
    15001 cgttactatt tgcatctaaa tataaagttg ttgcatatga tatagattct gtaaaaataa
    15061 ataatttaaa aaagggcact cttccatcta aaaatgaaga gcttatgaag tttttttgcg
    15121 agaataactt aaatattact ttttttgata cattttctga aattaaaaat aatattgatt
    15181 attatattat tgcgcttccg acagattatg atgagaaaat tggtagtttt aatacatatg
    15241 aaatcgaaca aacggtatcg aagattctga gggtaaaacc taatggaaag attattttaa
    15301 agtcaacagt tccgatcggc ttttcaaaca aattaaaaag gctgtttgat acaaaaaata
    15361 tcatttttgt ccctgaattt ttgagagaag gttgttctat atatgataat ttatatccaa
    15421 gtcgcatagt tgttggagat gagacagttg aaggaagaaa aattgcagag ttgttccttt
    15481 cgattagtac tcatagtact gccaatatta aaaatgttat gttagtttct cctactgaag
    15541 cagaagcaat taagcttttt tctaacacat tcttagctct ccgtgttgct ttttttaatg
    15601 aactagattc ttttgctgag aggagaagtt taaatgctga agttgtaata aaaggtgttt
    15661 gtttagatcc aagaattgga aatttttata ataatccttc ttttggattt ggaggatatt
    15721 gtcttcccaa agatactaaa caattaaaaa aagaatttat agaaataaat gccccagtga
    15781 tagaagcgat tgatatttca aacacaaata gaaaacagtt catagttaaa caaatattgg
    15841 aacgaaagcc aaagatagta ggaatatata aattggggat gaaatataat tcagataatt
    15901 acaaagagtc agctatttta agtataatta atgaactatt gattgtcggt ataaaaattt
    15961 tagtatatga accaaattta aacgttagta tagataacgt aatttttgaa aagaattttg
    16021 aactatttat aaaacaaagt gatctaattg ttgcaaatag atgggatagg gaccttgaag
    16081 cttataaaga taaagtttac acaaggggga tctggataag agattaacta ttgatattaa
    16141 aaaggcaata atttataaaa tttgtacaaa aaaatgttaa attttcacat tttcatagta
    16201 tactgtttaa tagaaagtag gttctttgta accgctccat tataaaatcc tttcactctt
    16261 ccggtatact attaggaaaa acataactgg aggatatttt gagctcacac ctcatcgttc
    16321 cagtggctgt tccccaagct cgtgtactgc ccaaaaaagt tagacattct atttagaacg
    16381 aggattgagt tctgtattgt acaaggctcg gtccttttag agtcagctta aggctggctt
    16441 tttcaatcac caaagtgtca gaatgttttg acaaatgaac acaaataatg atataatatg
    16501 caaaagctag gaggtggtag gatgattgaa aaaatggaac tgggggaatt ttacaaggaa
    16561 ttgcgcttgg cgagaaagct caagcagtca gatgtggctt gtgctggact aacagcctct
    16621 cagttgtcca agtttgaact aggacagtct atgctgtctg cagacaagct gatcctagcc
    16681 atccaaggga tcaatatgaa ttttgatgag tttgggcaca aactcaacaa ctatcaagaa
    16741 tctccacata tgcgaattgg tagaagggtt gtggattgct tttcccatca ggatatagct
    16801 gctttagagc agctattgga ggaagtcgat caagaacaga tggcgcagac ctatcgtcgt
    16861 ttgaatgcca ttgtgattaa aaatgcactc cattccttag ataaaagcta cccgctaaca
    16921 gaggaggata gcgagttttt gactacctac ctctacgcta ttgagtcttg gacctggttt
    16981 gaactctatc ttttttgcaa tactatgccc ttcttgagca atcaagatct gatcttttta
    17041 tcaacctcct tactcgaaaa atccaaggaa tttaaagagt tagtacacaa tcgatggtat
    17101 atgaaaagtg gttatcttaa tatcatctca gaacttatgg agcgcaagct attttcttat
    17161 attccaatct ttgaagctga gctggagcgc atgctccgtc catacgatgt ttttgaaaaa
    17221 gtattgtggc agtttttaaa gaaaatgcag atttttcttc aaaccaaagg aagcaatcaa
    17281 aaagagattg aacactttat ccaatctctg caagtattag aaaatccaca attgacagcc
    17341 ctttttgaat tgcgtttgca gcaatacaaa gagcttatcg attagttaga aatgggaaaa
    17401 agataataat atcagcaacg atcgtcaata atgttaaaac ttgtttcttc atattacttc
    17461 cctcctcatt agtaataact ttattatacc agggaaataa tcaaatctac caaaatcgca
    17521 aatctgaaat ttctataaga aaaaatatca aatatgcgat tttctaaaat aagccaattt
    17581 ccgtgttata ctgtccttgt aaaacatttg aagcaaatcc taggtcgcag aagtggttta
    17641 caaatgaaga taattgaagg agtgtaaaag atgttaaatt tacaatttgc agaaacaatg
    17701 gaattgacag aagctgagtt gcaagatgtt agaggaggca acctcgtaaa ttctatggga
    17761 ggtggtggaa gaagtggtat atctggttgg ggcgtcccag gaatttaccc tggttggggc
    17821 aatcaaggga tgagtcctaa tcgtggagct tttgattgga ctatagattt agcagatgga
    17881 ttgtttggcc gccgtagaag ataggctctt ataggagata ataggatgaa gaaaatgaaa
    17941 gaagtgaaat ttcacctagc aactggcttg ttgattttga cttattacct catttttaat
    18001 gtcacatcag acttagattt tatggttgct ttgtctgata atatgtacta tgtgttccaa
    18061 gttttattgg tacttattct gggaactata gctacaattg cttttgtcaa aagtgaacat
    18121 tggaaagagt gtggtcgttt ccagtttcgt tggtcttacc tgggtgtttt ccttctttct
    18181 tttttcttat tgttcgtgtg ggcaaatcta acaacctata tctttcctcg tacccagaat
    18241 ggaagtacag tcgtagaagt agccaccagt ttaacaggaa ttagctattt tgttacgcga
    18301 atactttata ctagtattat cgcacctgta tcagaagagg ttgtttgtcg tggtcttttg
    18361 atgacaagtt tatctaaagt taatagatac tatcttgatg ttcttgtttc cgctgccata
    18421 tttggcgcta tgcatgtttt gcagtatggt tggataacga cagatttcat aaagtatttt
    18481 ggaatgggct tgatattttg tatgatgttt cgctacaccc gatccatcta ttgggctata
    18541 gctctgcatg cttcatggaa tagcttctta ctcattgtta ctttattggt atttggatat
    18601 tagaaaggtg atatatgaaa aagataatct cacaccgcta ctttattata gtttttctac
    18661 tagttattgc tgaccagaag ttcagtgttt tagttttacg cagcgacctt gttgctgggc
    18721 tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg gttttatttg
    18781 ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga aagtttaaag
    18841 gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg aattttgtca
    18901 ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct gctcctactt
    18961 ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca ggtcccattt
    19021 ttgaagacat gatttatcgt ggattagtga tgactgctct ggaaaaagga aagaaatggg
    19081 ggctagatgt acttggttcc gctgttttat ttggggtctc gcacattagt aatcacggtt
    19141 gggtcttgac agactttgtc ttctatatgg gtggaggtct tatatttgca gtcttattta
    19201 gaatgacaaa gtcaatttat tggcctattg gactgcatat agtctacaat ggtattggtc
    19261 agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt cttggggaaa
    19321 gattcccatt tgaatttaaa aaggagttgt aatgaaagta tttcttcaaa atagagattt
    19381 taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt tttatctggc
    19441 cttcctgaat tatgtggcag atgcgtcttt tgcccctttg gcgattttac ttatcacgat
    19501 ttcagaaacc cttccccaag ttctacaaat ctttctggga gttttggcgg attttcaaca
    19561 tcatcgtgtc ttgaaataca cagtcattag ttttacaaaa tttttgcttt actctatagt
    19621 gtccctatcg ctttcagggc agtctttttc cttgttgcta gtaaccttta tttgtctgat
    19681 taacctcttg tctgacacat tgagttattt ttcaggcgcc atgctcactc cgattttcat
    19741 tagaattatt gggcaagatc atctggcaga agctattgga tttaaacagt caactgttag
    19801 tttagtgaaa acaatcagta atatcctagg aggagtctta ctaggtattc tatccatcca
    19861 gtttatttcc ttactgaacg ctcttacctt tttaatcgca tttttaggta tcctcttcat
    19921 aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac tctctgtaaa
    19981 atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga ataaggtgct
    20041 cttggttttg tttattatct ctactagtca agcagtgata aatgttacag ttcctgtctc
    20101 tactctattt ttgaggaatc aacccttttt gaatttacaa acaggtcaat ctcttgcctt
    20161 gctatccact tttgaactgt cagccccgat tgtcggaagc cttgtaagtg gctatctgca
    20221 acataccatt tccataaaaa cagctctcta tgcctcactt gtcatccagt tgcttcttct
    20281 agtaggattt gccacagttc gttttgactg gattctcatc tttagtacct tggatgcctt
    20341 tttcgcaggt gttctctctc ctagattgca agaactcgtc tttaaacaaa tacctgagga
    20401 gtcaatggga gcagttcaat cttctatcag tgccattacg gttgttttac ctagcttatt
    20461 tacaatatct ttggtaacca ttgctactag ctttggaact ctggcagtta gctttgtttt
    20521 attgctattt cttctagttg cctttgttat gcttctgaat attcgtgaaa gtatttagtg
    20581 gagaatttct ataatatatg tttgagactg gattgccagt ctttttatga tggtcaaaat
    20641 caacagactt ttttctcttt tctgaatgtg
//
LOCUS       DAVBOM010000038        20659 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBOM010000038 DAVBOM010000000
VERSION     DAVBOM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.038"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            163..2145
                     /locus_tag="VQ878_001486"
     CDS             163..2145
                     /locus_tag="VQ878_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3095810.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2446..7749
                     /locus_tag="VQ878_001487"
     CDS             2446..7749
                     /locus_tag="VQ878_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET3095811.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWKTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKAIITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGNMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIETLKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALTKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7916..10075)
                     /locus_tag="VQ878_001488"
     CDS             complement(7916..10075)
                     /locus_tag="VQ878_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET3095812.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQSAQP"
     gene            complement(10072..10668)
                     /gene="recU"
                     /locus_tag="VQ878_001489"
     CDS             complement(10072..10668)
                     /gene="recU"
                     /locus_tag="VQ878_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET3095813.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKRQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10734..11261
                     /locus_tag="VQ878_001490"
     CDS             10734..11261
                     /locus_tag="VQ878_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET3095814.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11331..11660
                     /gene="gpsB"
                     /locus_tag="VQ878_001491"
     CDS             11331..11660
                     /gene="gpsB"
                     /locus_tag="VQ878_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET3095815.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11681..12061
                     /gene="rnpB"
                     /locus_tag="VQ878_001492"
     ncRNA           11681..12061
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ878_001492"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12146..13303
                     /locus_tag="VQ878_001493"
     CDS             12146..13303
                     /locus_tag="VQ878_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET3095816.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13316..14710
                     /gene="mapZ"
                     /locus_tag="VQ878_001494"
     CDS             13316..14710
                     /gene="mapZ"
                     /locus_tag="VQ878_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET3095817.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14786..16210
                     /gene="gndA"
                     /locus_tag="VQ878_001495"
     CDS             14786..16210
                     /gene="gndA"
                     /locus_tag="VQ878_001495"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET3095818.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16222..16911
                     /locus_tag="VQ878_001496"
     CDS             16222..16911
                     /locus_tag="VQ878_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3095819.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17009..18028
                     /gene="cbpC"
                     /locus_tag="VQ878_001497"
     CDS             17009..18028
                     /gene="cbpC"
                     /locus_tag="VQ878_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET3095820.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18146..19378)
                     /locus_tag="VQ878_001498"
     CDS             complement(18146..19378)
                     /locus_tag="VQ878_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3095821.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19538..20008)
                     /locus_tag="VQ878_001499"
     CDS             complement(19538..20008)
                     /locus_tag="VQ878_001499"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095822.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(20175..20585)
                     /locus_tag="VQ878_001500"
     CDS             complement(20175..20585)
                     /locus_tag="VQ878_001500"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095823.1"
                     /translation="MQLLELSHTQGQLTDEQLFWLQCLLNLSQTNNLVKIKKIEEHKY
                     DYKTECNSVLRFLLDKTVNSEGRITSSTEFGNFVSNLSFQHGIAGLLFPLNKLYHPEL
                     DSKILSIIKKAVTIRTSHTYEYQYSLLFGGAGYL"
BASE COUNT         6424 a         3740 c         4633 g         5862 t
ORIGIN      
        1 agtctggaga tttttcaata gacttcgtta ttgggcggtt acgatattca tattttttgc
       61 aaagatgttg tttgaaaaat aattttcaaa aattctgaaa attctgttga catctttctg
      121 aaaagagtct ataatggaga gaaagtttta aaggagaaaa tgatgaaaag ttcaaaacta
      181 tttgcccttg cgggcgtgac attattggcg gcgactactt tagctgcatg ctctggatca
      241 ggttcaagta ctaaaggtga gaagacattc tcatacattt atgagacaga ccctgataac
      301 ctcaactatt tgacaactgc taaggctgcg acagcaaata ttaccagtaa cgtggttgat
      361 ggtttgctag aaaatgatcg ctacgggaac tttgtgccgt ctatggctga ggattggtct
      421 gtatccaagg atggattgac ttacacttat actatccgta aggatgcaaa atggtatact
      481 tctgaaggtg aagaatacgc ggcagtcaaa gctcaagact ttgtaacagg actaaaatat
      541 gctgctgata aaaaatcaga tgctctttac cttgttcaag aatcaatcaa agggttggat
      601 gcctatgtaa aaggggaaat caaagatttc tcacaagtag gaattaaggc tctggatgaa
      661 cagacagttc agtacacttt gaacaaacca gaaagcttct ggaattctaa gacaaccatg
      721 ggtgtgcttg cgccagttaa tgaagagttt ttgaattcaa aaggagatga ttttgccaaa
      781 gctacggatc caagtagtct cttgtataac ggtccttatt tgttgaaatc cattgtgacc
      841 aaatcctctg ttgaatttgc gaaaaatccg aactactggg ataaggacaa tgtgcatgtt
      901 gacaaagtta aattgtcatt ctgggatggt caagatacca gcaaacctgc agaaaacttt
      961 aaagatggta gccttacagc agctcgtctc tatccaacaa gtgcaagttt cgcagagctt
     1021 gagaagagta tgaaggacaa tattgtctat actcaacaag actctattac gtatctagtt
     1081 ggtacaaata ttgaccgtca gtcctataaa tacacatcta agaccagcga cgaacaaaag
     1141 gcatcgacta aaaaggctct cttaaacaag gatttccgtc aggctattgc ctttggattt
     1201 gaccgtacag cctatgcctc tcagttgaat ggacaaactg gagcaagtaa aatcttgcgt
     1261 aatctctttg tgccaccaac atttgttcaa gcagatggta aaaactttgg cgatatggtc
     1321 aaagagaaat tggtcactta tggggatgaa tggaaggatg ttaatcttgc agattctcag
     1381 gatggtcttt acaatccaga aaaagccaag gctgaatttg ctaaagctaa atcagcctta
     1441 caagcagaag gagtccaatt cccaattcat ttggatatgc cagttgacca gacagcaact
     1501 acaaaagttc agcgcgtcca atctatgaaa caatccttgg aagcaacttt aggagctgat
     1561 aatgtcatta ttgatatcca acaactacaa aaagacgaag taaacaatat tacatatttt
     1621 gctgaaaatg ctgctggcga agattgggat ttatcagata atgtcggttg gggtccagac
     1681 tttgccgatc catcaaccta ccttgatatc atcaaaccat ctgtaggaga aagtactaaa
     1741 acatatttag ggtttgactc aggggaagat aatgtagctg ctaaaaaagt aggtctatat
     1801 gactacgaaa aattggttac tgaggctggt gatgaggcta cagatgttgc taaacgctat
     1861 gataaatacg ctgcagccca agcttggttg acagatagtg ctttgattat tccaactaca
     1921 tctcgtacag ggcgtccaat cttgtctaag atggtaccat ttacaatacc atttgcattg
     1981 tcaggaaata aaggtacaag tgaaccagtc ttgtataaat acttggaact tcaagacaag
     2041 gcagtcactg tagatgaata ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag
     2101 tctaataaaa aggctcaaga agatctcgca aaacatgtga aataactgtt gcaaaatata
     2161 agaaaggatt tagtatttct cttgaatgct gaatcctttt ttacatttgt aaagaaagct
     2221 tctaaatgta ctgaccccca aaagttggag cctctttttg tcagaataga gaaaattttt
     2281 gttaatttta cttgtttcct attgctttct cagttattat ttgttatatt aaaagtataa
     2341 ttatttttta tttatcaggg ttaagcattg cactttcaga ggaaggagta ttttttaaaa
     2401 aggaaatgta aacgcttgct aaaaaatgaa aggatttaga agtttatgaa taaaggatta
     2461 tttgaaaaac gttgtaaata tagtattcgg aaattttcat taggtgttgc ttctgttatg
     2521 attggagctg cattctttgg gacaagtccg gttcttgcag atagcgtgca gtctggttcc
     2581 acggcgaact taccagctga tttagctact gctcttgcaa cagcaaaaga gaatgatgga
     2641 cgtgattttg aagcgcctaa ggtgggagaa gaccaaggtt ctccagaagt tacagatgga
     2701 cctaagacag aagaagaact attagcactt gaaaaagaaa aaccggctga agaaaaacca
     2761 aaagaggata aacctgcagc tgctaaacct gaaacaccta agacggtaac ccctgaatgg
     2821 aaaacggtag agaaaaaaga acaaaaggga acagtcacta tccgagaaga aaaaggtgtc
     2881 cgctacaacc aactatcctc aactgctcaa aatgataacg caggtaaacc agccctgttt
     2941 gaaaagaagg gcttgaccgt tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa
     3001 gatgattctg aaaagggcaa atcacgcttt ggtgtcttct tgaaatttaa agataccaat
     3061 aataatgttt ttgtcggtta tgacaaggat ggctggttct gggagtataa atctccaaca
     3121 actagcactt ggtatagagg tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt
     3181 ctctctatca ctctcaagtc agacggtcag ctaaatgcca gcaataacga tgtcaatctc
     3241 tttgacacag tgactctacc agctgcggtc aatgaccatc ttaaaaatga gaagaagatc
     3301 cttctcaagg cgggctctta tgacgatgag cgaacagttg ttagcgttaa aacggataac
     3361 caagaggggg taaaaacaga ggatacccct gctgaaaaag aaacaggtcc tgaagttgat
     3421 gatagcaagg tgacttatga cacgattcag tctaaggtcc tcaaagcagt gattgaccaa
     3481 gccttccctc gtgtcaagga atacaccttg aatggacata ctttgccagg acaggtgcaa
     3541 cagttcaacc aagtctttat caataaccac cgaatcaccc ctgaagtcac ttataagaaa
     3601 atcaatgaga caacagcaga gtacttgatg aagcttcgcg atgatgctca cttaatcaat
     3661 gcggaaatga cagtacgctt gcaagttgtg gacaatcaat tgcactttga tgtgaccaag
     3721 attgtcaacc acaatcaagt cactccaggt caaaagattg atgacgaaag aaaactactt
     3781 tcttctatta gtttcctcgg caatgcttta gtctctgttt ctagtgatca aactggtgct
     3841 aagtttgatg gggcaaccat gtcaaacaat acgcatgtca gcggagatga tcatatcgat
     3901 gtaaccaatc caatgaagga tttggctaag ggttacatgt atggatttgt ttctacagat
     3961 aagcttgctg ctggtgtttg gagtaactct caaaacagct atggtggtgg ttcgaatgac
     4021 tggactcgtt tgacagctta taaagaaaca gtcggaaatg ccaactatgt aggaatccac
     4081 agctctgaat ggcaatggga aaaagcttat aagggcattg ttttcccaga atacacgaag
     4141 gaacttccaa gtgctaaggt tgttatcact gaagatgcca atgcagacaa gaacgttgat
     4201 tggcaagatg gtgccattgc ttatcgtagc attatgaaca atcctcaagg ttgggaaaaa
     4261 gttaaggata tcacagctta ccgtatcgcg atgaactttg gttctcaagc acaaaaccca
     4321 ttccttatga ccttggatgg tatcaagaaa atcaatctcc atacagatgg tcttgggcaa
     4381 ggtgttctcc ttaaaggata tggtagcgaa ggccatgact ctggtcactt gaactatgct
     4441 gatattggta agcgtatcgg tggtgtcgaa gacttcaaga ccctaattga gaaggctaag
     4501 aaatatggag ctcatctagg tatccacgtt aacgcttcag aaacttatcc tgagtctaaa
     4561 tacttcaatg aaaaaattct ccgtaagaat ccagatggaa gctatagcta tggttggaac
     4621 tggctagatc aaggtatcaa cattgatgct gcctatgacc tagctcatgg tcgtttggca
     4681 cgttgggaag atttgaagaa aaaacttggt gacggtctcg actttatcta tgtggacgtt
     4741 tggggtaatg gtcaatcagg tgataacggt gcctgggcta cccacgttct tgctaaagaa
     4801 attaacaaac aaggctggcg ctttgcgatc gagtggggcc atggtggtga gtacgactct
     4861 accttccatc actgggcagc tgacttgacc tacggtggct acaccaataa aggtatcaac
     4921 agtgccatca cccgctttat ccgtaaccac caaaaagatg cttgggtagg ggactacaga
     4981 agttatggtg gtgcagccaa ctatccactg ctaggtggct acagcatgaa agactttgaa
     5041 ggctggcaag gaagaagtga ctacaatggc tatgtgacta acctctttgc tcatgacgtc
     5101 atgactaagt acttccaaca cttcactgta agtaaatggg aaaatggtac accggtgact
     5161 atgaccgata acggtagcac ctataaatgg actccagaaa tgcgagtgga gttggtagat
     5221 gctgacaata ataaagtagt tgtaactcgt aagtcaaatg atgtcaatag cccacaatat
     5281 cgcgaacgta cagtaacgct caacggacgt gtcatccaag atggttcagc ttacttgact
     5341 ccttggaact gggatgcaaa tggtaagaaa ctttctactg agaaggaaaa gatgtactac
     5401 ttcaatacgc aggccggtac aacaacttgg acccttccaa gcgattgggc aaagagcaag
     5461 gtttaccttt acaagctaac tgaccaaggt aagacagaag agcaagaact aactgtaaaa
     5521 gatggtaaaa ttaccctaga tcttctagca aatcaaccat acgttctcta tcgttcgaaa
     5581 caaaccaatc ctgaaatgtc atggagtgaa ggcatgcaca tctatgacca aggatttaat
     5641 agcggtacct tgaaacattg gaccatttca ggcgatgctt ctaaggcaga aattgtcaag
     5701 tctcaagggg caaacgatat gcttcgtatt caaggaaaca aagaaaaagt tagtctcact
     5761 cagaaattaa ctggcttgaa accaaatacc aagtatgccg tttatgtcgg tgtcgataac
     5821 cgtagtaatg ccaaggcgat catcactgta aacactggtg aaaaagaagt gactacttat
     5881 accaataagt ctctcgctct caactatgtt aaggcctacg cccacaatac acgtcgtgac
     5941 aatgctacag ttgacgatac aagttacttc caaaacatgt acgccttctt tacaactgga
     6001 tcggacgtct caaatgttac tctgacattg agtcgtgaag ctggtgatga agcaacttac
     6061 tttgatgaaa ttcgtacctt tgaaaacaat tcaagcatgt acggagacaa gcatgataca
     6121 ggtcaaggaa ccttcaagca agactttgaa aatgttgctc agggtatctt cccatttgta
     6181 gtgggtggtg tcgaaggtgt cgaagacaac cgcactcact tgtctgaaaa acacgatcca
     6241 tatacacaac gtggttggaa cggtaagaaa gttgatgatg ttatcgaagg aaattggtca
     6301 ctcaagacaa atggactagt gagccgtcgt aacttggttt accaaactat tccgcaaaac
     6361 ttccgttttg aagcaggtaa gacctaccgt gtaacctttg aatacgaagc aggttcagac
     6421 aatacctatg cttttgtagt cggtaaggga gaattccagt caggtcgtcg tggtactcaa
     6481 gcaagcaact tggaaatgca tgaattgcca aatacttgga cagattctaa gaaagccaag
     6541 aaggcaacct tcctcgtgac aggtgcagaa acaggggata cttgggtagg tatctactca
     6601 actggaaatg caagtaatac tcgtggtgat tctggtggaa atgccaactt ccgtggttat
     6661 aacgacttca tgatggataa tcttcaaatc gaagaaatta ccctaacagg taatatgttg
     6721 acagaaaatg ctctgaagaa ctacttgcca acggttgcca tgactaacta caccaaagag
     6781 tctatggatg ctttgaaaga ggcggtcttt aaccttagtc aggccgatga tgatatcagt
     6841 gtggaagaag cgcgtgcaga gattgccaag attgaaacct tgaagaatgc tttggttcag
     6901 aagaaaacgg ctttggtagc agatgacttt gcaagtctta cagctcctgc tcaggctcaa
     6961 gaaggtcttg caaatgcctt tgatggaaac ttatctagtc tatggcatac atcttggaat
     7021 ggtggagatg taggcaagcc tgcaaccatg gtcttgaaag aaccaactga aatcactgga
     7081 cttcgttatg ttccacgtgg atcaggttca aatggtaact tgcgtgatgt gaaacttgtt
     7141 gtgacagatg agtctggcaa ggagcatacc tttactgcaa ctgattggcc agataacaat
     7201 aagccaaaag acattgattt tggtaagaca attaaggcta agaaaattgt ccttacaggt
     7261 actaagactt acggagatgg tggcgataaa taccaatctg cagcggaact catctttact
     7321 cgtccacagg tagcagaaac acctcttgac ttgtcaggct atgaagcagc tttgactaag
     7381 gctcagaaat taacagacaa agacaatcaa gaggaagtag ctagcgttca ggcaagcatg
     7441 aaatatgcga cggataacca tctcttgacg gaaagaatgg tggaatactt tgcagattat
     7501 ctcaaccaat taaaagattc tgctacgaaa ccagatgctc caactgtaga gaaacctgag
     7561 tttaaactta gctctttagc ttccgagcaa ggtaagacgc cagattataa gcaagaaata
     7621 gctagaccag aaacacctga acaaatcttg ccagcaacag gtgagagtca atctgacaca
     7681 gccctcttcc tagcaggtgt tagcctagcc ctatctgctc tctttgtagt aaaaacgaag
     7741 aaagactagt atttagtaaa acctcttaac aagattacgg aagcagtctc tatcttttcc
     7801 aatgaggttt atagtacaga aaaagcctga gaagatgtct tctcaggctt ttgttaagca
     7861 cataaataca atagtgctat gaaaaaatca cccagaaaaa tctgggtgat aaatgttatg
     7921 gttgtgctga ttgaggattc tgattttgtt gatcaggggt tgtatttgat tgttgcgtat
     7981 tattgttagg attggtagtc gtactattat ttgtgcttgg agtggttgag ctagactgtg
     8041 aagttgaact atctgatgat gagcttgaac tttcagttga tgggggttgt tgtggagcag
     8101 gtgagctcca cgtagaacga gcaccatttt taaatacgaa ttctccattt ctgtagagcc
     8161 cctctggtat attccaatcc tctggattgc ttccttcaga caggtaggtc atcatagagc
     8221 ggtaaacttt ggcagcgacc gtaaggccat tgcctacaag tggtgtcaga cggttagaat
     8281 agcctgtcca tacagccatt gaatatttac gcgtatagcc agcaaatagt tcatcaggtg
     8341 ctacaaattg agaggtcttg atgtggtttt caatttcctc gtctgtatag ttagaggttc
     8401 ctgttttacc agcctgaggg agccaagcaa gataggcatt tcgtccagtt ccataactca
     8461 agactgtttt catcatgtcg gtcatcatat aggctgtcgt ttccttcatg gcacgagttc
     8521 cgacattaga gaactctttt tcactcccat cactaaagac gactttatgg atatacattg
     8581 gtttatagta agttccacca tttgcaaagg cagcgtaagc agcagccatc ttttcactac
     8641 ttgctccata ttttttgtct gattcggttg tgttacttga aatggcattt gagtagtgaa
     8701 tacttgggta gtcgattccg agaccattta ggaaagtctt ggcgcggttg agtccgacct
     8761 tgtttagagt ttccacggct gggacgtttc gcgattgttg cagggcgtat tgcaaggtga
     8821 tgttgccaaa gtagccccta tcccagttat aaacaggagt atttgtccca gggtagttat
     8881 agggctcatc gtgaacgata gtagcagttg aatcgtagac accgtactcc aaggcaggag
     8941 catagtctgt gatcggtttc atagttgatc cccagtcgcg gtttgtttct actgcttggt
     9001 taattccgaa ggaaacatta cttgactgat ggcgtgctcc tagctgggca atgactttac
     9061 cgttagaaac atcaacaatg gtagaagcga cttgcaattc atcgtctgga taggcaacgt
     9121 attcgtctgt attgtaaata tcccacagat gtttttgagc ttcttggtct acatttgtgt
     9181 agacatccat cccagttgtg agcaggttat agcctgtttc ttcttcaact tgattgatga
     9241 cttccttgag gtaattatcc atgtaagcag ggtaattact tgctgatttg agactttgta
     9301 gtccatcagt aattggtgta ttgactgctt tctcatactg ttcagcagag atgtagcctt
     9361 gatttttcat ttcagataag accaagtttc ggcggtcttg ggctgcttct ggatgtgaat
     9421 aggggtcata ttggtttggt gcctgaggca ttccagccag caaggctaac tgaggtaaac
     9481 ttaaattatt gaggtcttta ccatagtagt tttgagctgc tgtctgcatt ccatagttcc
     9541 cattagacat gtagacctta tttatatagt aggtcaagat ttcttgcttg gttgcttttt
     9601 gttctaactg aatcgctaac caagcttcct gagccttacg agaaatagtc tggtcggaag
     9661 tcgaagttga aaagtaagtc aacttaatca actgttgagt gagagttgat ccaccttgga
     9721 gggaattgct ttgcagattg cgcaagaaag ctcccaggat acggatggta tcaatccccc
     9781 tgtggtcgaa gaagcgatgg tcttcgatag aaacgattgc cttaaccaaa tctgtgggaa
     9841 tatcattagc ttgggcattg acgcggcgtt cagaacccaa gtcagcaatg agttgatttt
     9901 tattgtcgta gattttacta gaagttgttg caactagttt actctcggat aggctaggag
     9961 ccttgctaac gtagtagaaa aaaactcctc cgcctaagac aatggctgcg ataaccaagc
    10021 ttaagaagct aatgctcaga tacttgatta ggcgcagaat cgttggtttg ttcatcttgt
    10081 tttaccacct aataaatgtt ctttgataac attgagataa ggaatttgag ggaaggcacc
    10141 agccttgatt tcatatccat attctcgaat atattcaagt ggcattgatt tttgtctctt
    10201 atcttgatga tagaagcgaa tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga
    10261 agaaaagtga agaaggacaa agcagattcc ttgttgggca aggacttgtt ccatatgctg
    10321 aatctgatgt ggatgaaaat ttttcatcgg aatcgcacgt ttttgttttg tttccttgac
    10381 ttcaaagtcg atgtaatatc cattataaac gccagaatag tccgtcgttg aagcttgtcg
    10441 aaaataggct tcaacaatct tggcacgact tcgttgtgga tagtccactt gtacgatttg
    10501 aataggagtt ggtttcttat gtataacagc caagccctga gacaaatagt agtcgttggt
    10561 agcattgatc atcttttcaa aagacattcc tcgatttgcg aaatttttgg gttgagaaag
    10621 agatgtttgt cttttttgtg atgaaacttt atgtggatag ttgaccataa ttctccttat
    10681 tggtacaata acatcacttt attataccat aatttgcaca gaaagggtta aaaatggcta
    10741 cagctttggt tttaggctat tctgcttttg atttgggttt attttctgat aaggatcctc
    10801 gtcttaaatt gattaaaaaa gcgatacgta aagatttaga ggctatggca gcagatgggg
    10861 tgtcttggct tgtgtttaca gggagtttgg gttttgaata ttgggtttta gaggttgctc
    10921 aggagatgaa aaccgaatac ggtttccagt tggccaccat ttttgctttt gaaacccatg
    10981 gggaaaattg gaatgaaggc aatcagatga aactgagtcg ctttaagcag gtagactttg
    11041 tcaaatatgc ttatcctcgc tatgaacaca aggggcagtt aagagattac cagcagtttt
    11101 tgctggaaaa cacgactagt tcctatcttt tttatgatga agaaaatgaa acaaaactag
    11161 cttattttta ccaaaagatg aaaaatcaag aggactattt tataaagaga ttaacatttg
    11221 atgaattaaa tgaacttgct gaaaattttt ccgaaaattg aagctttgac cttgattttt
    11281 gtttgccttt ttttatataa taatactagc aagcgagaat ggagagagac atggcaagta
    11341 ttattttttc agcgaaagat atttttgaac aagagtttgg acgtgaagtc cgtggctata
    11401 ataaagtaga agttgacgag tttttagacg atgtcatcaa ggactatgaa acctatgctg
    11461 ccttggtcaa gtcacttcgt caggaaattg cggatttgaa ggaagaatta actcgtaaac
    11521 cgaaaccttc accagttcaa gcagaacccc ttgaagcggc aattacaagt tctatgacga
    11581 attttgatat tttgaaacgc ctgaatagat tggaaaaaga agtttttggt aaacaaattt
    11641 tagataactc agatttttaa gtagttattt gagatgtgca atttttggat aatcgcgtga
    11701 ggagaattgc ttctcatgag gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt
    11761 tgtgctaggc gaaaccataa gcctagggac gagaaatcgt tacggcagtt gaaatggcta
    11821 agtccttgga taggccagag taggcttgaa agtgccacag tgacggagtc tttctggaaa
    11881 cagagagagt ggaacgcggt aaacccctca agctagcaac ccaaattttg gtcggggcat
    11941 ggagtacgcg gaaacgaacg tagtattctg actgctatca gctagagctg ttagtggtag
    12001 acagatgatt atcgaaggaa gtggtcctag tcacttctgg aacaaaacat ggcttataga
    12061 aaattgcata taggttgggg ctgagaaatt ttctcaacct cattttttaa agtggacata
    12121 tagaaaggtc ttgcaagact gtaacatgaa aaaagaattt aatttaattg caactgtggc
    12181 agcagggctt gaggctgtcg ttggtcgtga agtgcgagag ttgggctacg attgtcaggt
    12241 tgaaaatgga cgtgttcgtt ttcaaggaga cgtgagagct attatcgaaa ccaacctttg
    12301 gcttcgggca gcagatcgta tcaaaattat cgtaggaacg ttcccagcta agacttttga
    12361 agagctattt cagggagttt tcgctttaga ttgggaaaat tatttaccac ttggagctcg
    12421 gttcccgatt tcaaaagcta aatgtgttaa gtccaaactt cacaatgagc ccagtgttca
    12481 ggctatttct aagaaagctg ttgtcaagaa attgcagaaa cactatgctc gcccagaagg
    12541 ggttcctctg atggagaatg gcccagagtt taagattgag gtctctattc tcaaagatgt
    12601 ggcaactgtc atgattgata cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga
    12661 aaaaggtggc gctcctatca aggaaaatat ggcagcagcc attttacaac tttctaactg
    12721 gtatccagac aagcctttga ttgatccgac ctgtggttcg gggactttct gtattgaggc
    12781 agttatgatt gctagaaaga tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg
    12841 gaactggatc agcgatcgct tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga
    12901 acgtgagctt gagttggata tcatgggctg tgatattgat gctcgcatgg tggaaattgc
    12961 taaggccaat gctcaggcag ctggtgttgc aggagacatt acttttaagc agatgcgcgt
    13021 gcaggattta cgttccgata aaatcaatgg agtaatcatt tccaatccgc cttatggtga
    13081 acgtttgtca gatgatgcag gggtgaccaa gctctatgct gagatggggc aagtatttgc
    13141 accgctgaaa acttggagca aatttatcct gactagtgat gaagcttttg aaagcaagta
    13201 tggtagccaa gcagataaga agcgtaagtt atacaacgga accttgaaag tggatctata
    13261 tcaatatttt ggtcagcgtg tcaaacggca agaggtaaaa tagaaaggga tactcatgag
    13321 taaaaaaaga cgaaatcgtc ataaaaaaga aggtcaagaa ccgcaatttg attttgatga
    13381 agcaaaagag ctaacagttg gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt
    13441 cttgcctgag gattccattt tggacaagta tgttaagcaa cacagagatg aaattgaggc
    13501 ggataagttt gcgactcgtc aatacaaaaa agaggagttc gttgaaactc agagtctgga
    13561 tgatttaatt caagagatgc gtgaggctgt agagaagtca gaagcttctt cggaggaagt
    13621 tccatcttct gaagacatct tactaccctt gcctctggac gatgaggagc aaggcttgga
    13681 tcctctattg ctagatgatg aaaatccaac agaaatgact gaagaagtgg aagaggagca
    13741 aaacctttct cgtctggatc aagaggactc agaaaagaaa agtaaaaaag gctttatttt
    13801 gaccgttttg gcgcttgtat cagtaattat ttgtgtcagt gcttattatg tctaccgtca
    13861 agtggctcgt tcgaccaagg aaattgaaac ttctcaatca actacagcca atcaatcaga
    13921 tgtggatgat tttaatacac tttatgacgc cttttacaca gatagcaata aaacggcttt
    13981 gaaaaatagc cagtttgata aactgagtca actcaaaacc ttgcttgata aactggaagg
    14041 tagtcgtgaa catacgcttg ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc
    14101 tattcaagat gtcaatgcac aatttgaaaa accagctatt gtggatggtg tgttggatac
    14161 caatgccaaa gccaaatcgg atgctaaatt tacggatatt aaaactggaa atacggagct
    14221 tgataaagtg ctagataagg ctatcagtct tggtaagagc cagcaaacaa gtacttctag
    14281 ctcaagttca agtcaaacta gcagctcaag ctctagtcaa gcaagttcaa atacgactag
    14341 tgagccaaaa ccaagtagtt caaatgagac tagaagtagt cgcagtgaag tcaatatggg
    14401 tctctcgagt gcaggggttg ctgttcaaag aagtgccagt cgtgttgcct ataatcagtc
    14461 tgctattgat gatagtaata actctgcctg ggattttgcg gatggtgtct tggaacaaat
    14521 tctagcgact tcacgttcac gtggctatat cactggagac caatatatcc ttgaacgtgt
    14581 caatatcgtt aacggcaatg gttattacaa cctctataag ccagatggaa cctatctctt
    14641 tacccttaac tgtaagacag gctactttgt cggaaatggc gctggtcatg cggatgactt
    14701 ggactactaa gcagtcgtta caaaattctt tcttttcaaa agtaaaaatg ataaaataaa
    14761 acaaatgaaa caagaggagt gtcaaatgac aaaagctaac tttggtgtcg taggtatggc
    14821 cgtaatgggt cgtaaccttg cccttaatat tgaatcacgt ggttacacag ttgctatcta
    14881 caaccgtagt aaagaaaaaa cggaagatgt gattgcttgc catcctgaaa agaactttgt
    14941 accaagctat gacgttgaaa gttttgtaaa ctcaatcgaa aaacctcgtc gtatcatgct
    15001 gatggttcaa gctggacctg gtacagatgc tactatccaa gcccttcttc cacaccttga
    15061 caagggtgat atcttgattg acggtggaaa tactttctac aaagatacca tccgtcgtaa
    15121 tgaagaattg gcaaactcag gtatcaactt tatcggtact ggagtttctg gtggtgaaaa
    15181 aggtgccctt gaaggtcctt ctatcatgcc tggtggacaa aaagaggcct acgaattggt
    15241 tgcggatgtt cttgaagaaa tctcagctaa agcaccagaa gatggcaagc catgtgtgac
    15301 ttacatcggt cctgatggag ctggtcacta tgtgaaaatg gttcacaatg gtattgagta
    15361 cggtgatatg caattgatcg cagaaagcta tgacttgatg caacacttgc taggcctttc
    15421 tgcagaggat atggctgaaa tctttactga gtggaacaag ggtgaattag acagctactt
    15481 gatcgaaatc acagctgata tcttgagccg taaagacgat gaaggccaag atggaccaat
    15541 cgtagactac atccttgatg ctgcaggtaa caagggaact ggtaaatgga cgagccaatc
    15601 atctcttgac cttggtgtac cattgtcact gattactgag tcagtgtttg cacgctacat
    15661 ttcaacttac aaggaagaac gtgtacatgc tagcaaggtg cttccaaaac cagctgcctt
    15721 caactttgaa ggagacaagg ctgaattgat tgaaaaaatc cgtcaagccc tttacttctc
    15781 aaaaatcatt tcatacgcac aaggatttgc tcaattgcgt gtagcctcta aagaaaacaa
    15841 ctggaacttg ccatttgcag atatcgcatc tatctggcgt gatggctgta tcatccgttc
    15901 tcgtttcttg caaaagatta cagatgctta caaccgcgat gcagatcttg ccaaccttct
    15961 tttggacgag tacttcttgg atgttactgc taagtatcaa caagcagtgc gtgatatcgt
    16021 agctcttgcg gttcaagctg gtgtgccagt gccaactttc tcagcagcta ttacttactt
    16081 tgatagctac cgttcagctg accttccagc taacttgatc caagcacaac gtgactactt
    16141 tggtgctcac acttaccaac gtaaagacaa agaaggaacc ttccactact cttggtatga
    16201 cgaaaaataa gtaggtcagc catggggaaa cggattttat tacttgagaa agaacgaaat
    16261 ctagctcatt ttttaagttt ggaactccag aaagagcagt atcgggttga tctggtagag
    16321 gaggggcaaa aagccctctc catggctctt cagacagact atgatttgat gttattgaac
    16381 gttaatctgg gagatatgat ggctcaggat tttgcagaaa aattgagtcg aactaaacct
    16441 gcctcagtca tcatgatttt agatcattgg gaagacttgc aagaagagct ggaagttgtt
    16501 cagcgttttg cagtttcata catttataag ccagtcctta tcgaaaatct ggtagcgcgt
    16561 atttcggcga tcttccgagg tcgggacttc attgatcaac actgcagtct gatgaaagtt
    16621 ccaaggacct accgcaatct taggatagat gttgaacatc acacggttta tcgtggtgaa
    16681 gagatgattg ctctgacccg ccgtgagtat gaccttttgg cgacacttat gggaagcaag
    16741 aaagtattga ctcgtgagca attgttggaa agtgtttgga agtatgaaag tgcgaccgag
    16801 acaaatatcg tagatgtcta tatccgctat ctacggagca agcttgatgt taaaggccaa
    16861 aaaagctaca ttaaaaccgt gcgtggtgtt ggatatacca tgcaagaata gataagcagt
    16921 tgcagttgtg taactgcttt tttgaggagt ttttatatat tgacatgcag tcgggtcttt
    16981 gctacaatcg ttttaggagg atatatagat gaaacttttg aaaaaaatga tgcaagttct
    17041 actagcagtc tttttctttg gtttgctagc tacaaatacg gtatttgcga ataccacagg
    17101 tggccgattt gttgataagg ataatagaaa atattatgta aaagatgatc ataaagcaat
    17161 ctattggcat aaaatagacg gtaaaactta ctattttggt gatattggag agatggttgt
    17221 cggttggcaa tacttagaaa ttcctggaac aggttatcgt gataatttat tcgataacca
    17281 accagttaat gaaattggcc ttcaggagaa gtggtactat tttggacaag atggtgcttt
    17341 gctagaacaa acagataaac aagtactaga ggcaaaaacg tctgaaaata caggaaaagt
    17401 atacggtgaa caatatcctc tatctgctga aaagagaact tattattttg ataataatta
    17461 tgctgtaaag acaggctgga tttatgaaga cggcaattgg tattatttaa ataagctagg
    17521 aaattttggc gatgattctt acaatccact accaattagt gaagttgcta agggttggac
    17581 tcaagatttt catgttacta ttgacattga tagaagcaaa cctgctccat ggtactacct
    17641 agacccagaa actggcatta tgcgaacagg atggcaatat ctaggtaata actggtacta
    17701 cctccgttca tcaggagcaa tggccactgg ctggtatcag gaaggtacca cttggtatta
    17761 tttagaccag ccaaatggcg atatgaaaac aggttggcaa aaccttggga acaaatggta
    17821 ctatctccgt tcatcaggag ctatggcaac tggttggtat caagatggtt caacttggta
    17881 ctacctaaat gcaggtaatg gagacatgaa gacaggttgg ttccaggtca atggcaactg
    17941 gtactatgct tatagctcag gtgctttggc agtgaatacg accgtagatg gctattctgt
    18001 caactataat ggcgaatggg ttcggtaatg acagggcgct tataattata ttagaacact
    18061 cgcttaatca aagaagtgac tttgttgtac ttgacctgac gattggggag attaaaagca
    18121 tgtgaaatct acacatgctt tttcgttagt tatgagtgtt gaacttgact aaccattgac
    18181 aaaagataag agcaattaaa ataagataca aaaatatcaa tgctaactgc accgaaacgc
    18241 ccgatgctat ggatagggct aatagggaga gcagggacgg ggcgagaatg tccactgtgc
    18301 tcagagcaga gcccaccgtc cccatcttgt cactggggat ataggcaaag acagctgctt
    18361 gtaggcgagg gctgagaatg ccgataatcg tagaactgat gaaactggtc atgaaaatta
    18421 cgatataggc ttgacaaagg atactagtta ttagagccaa tagggaaatc tcacagaaaa
    18481 ccaagaggtg cgtgaaacgg atatttttaa atagattact gctggtcata ttgccaagga
    18541 tagctccaca agacatgatg atggagagca gggcgaggag ttgcccaatg ctcagttgtg
    18601 ctagtgtctg ttggatgaag cggagggcaa tcagccgagg ggacacatcc aagatggcaa
    18661 tcatactggt cgtcagaaac agtagtatga cggtatcttt taacttcagt agcacagcca
    18721 gcgactgttt aagatgttga aaatatttct taaaactcag tgctgtatgt gacatttcaa
    18781 tccttttttc aacctcatac aaggtatgtc gaataacata caggcccaaa aaggcaatga
    18841 caaaagtcag agtgttgata agggaaatag tttgaatact tataacattg ataaggaatg
    18901 cgccagccag attggcgaca atgcggacaa ccctcatcag agactgcctg aaccccatgg
    18961 catcatgcag gtcgtcctta attacactga tgtagagggc gttcatcatg taggcagaca
    19021 ggtagctcaa ggtgtcagag atgaggttga tgatgacaat cataatgact gaaactaatg
    19081 aaaagggcga caagacgaga aatactgtca aaatagcgta gagcaggatt ttgattttgg
    19141 caatacagag tgcgtgtttg actctatttt cttgaaaatc tcctagaatc ccgagaaaga
    19201 gttgcgatag taggggaacc atctctgaaa tggaaatcag taaaatcgct agcggagcga
    19261 aattgtactg agccacataa ttgataatgg cgaggtagaa aatactgtcg ccgaatgatg
    19321 aaaaacagct gtttagcagc aactgtctat atatgttgtt tgtccaaaat aatttcatac
    19381 atttctcctt atgtctgcac atcgaatggg aatttattat ttaatagaca ccaatatacc
    19441 cccatgcttc ctattccgaa gtcaaacaaa tctgctttac cactatctcc ttgaaacatc
    19501 agtaaaccgt gatcatctcg ttcagaacat gctaaaatta cctgttggat tttttcatca
    19561 gtaatttgtt ttgattgtag acagtggttt gtagtaagct agttattccg tggcaatatc
    19621 ctgtcatcat ttttagatga tggttaaaaa caaattcttg atatttacta ataatatctt
    19681 tgtttccgtc acaatcgtac atacaaagat ataagattat tccggaaatt cctttgcacc
    19741 aagaaagttg taaatttcct aaattttcag tattagaagt aactttttct aataattttt
    19801 ttaattcagt atggaatgta tggagatcat tatagaacat agaaggttct aagactttag
    19861 aataggcaaa taaagcatat gcaattccac aatatccatg agcaaagcta tagtctaaaa
    19921 tgctttcttt ggctgtatct ctttgtagga aataatgata aatttcccca tatactattg
    19981 tggatgaaag ttttaagagt attgtcattg gtaacttgat agtattttat taatgataat
    20041 aggacaccag attttcccaa tgcaaagtct atttcctcta gagtatcata attctctatt
    20101 aatttcttag cggtgacgtt tgctaattgt agatagtatt gatttttact gatagaaaat
    20161 aaatgtagga gtaactatag atagcctgca ccaccaaata gcagtgagta ttgatattca
    20221 tatgtgtgtg acgttctaat tgtcactgcc ttcttgatga tagagagtat tttagaatcc
    20281 agttctgggt ggtacaattt atttagagga aacagtagtc cagctattcc gtgttggaat
    20341 gataaattac ttacgaaatt tccaaattct gttgaagaag tgatccttcc ttcagaattt
    20401 acagttttat ctagtaaaaa tcgtagaaca ctattacatt ctgttttgta atcatattta
    20461 tgttcctcta tttttttaat tttgactaaa ttatttgttt gacttaaatt tagtagacat
    20521 tgtaaccaaa atagttgctc atctgtgagc tgaccttgag tatgtgatag ttctagtaat
    20581 tgaataggat cctttagtta gattcaatca atctataaca caacaacata ataatacttt
    20641 taggataact tgtcaaata
//
LOCUS       DAVBOM010000039        20054 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBOM010000039 DAVBOM010000000
VERSION     DAVBOM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.039"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            638..952
                     /locus_tag="VQ878_001501"
     CDS             638..952
                     /locus_tag="VQ878_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3095824.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            968..1354
                     /locus_tag="VQ878_001502"
     CDS             968..1354
                     /locus_tag="VQ878_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3095825.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1383..2768
                     /locus_tag="VQ878_001503"
     CDS             1383..2768
                     /locus_tag="VQ878_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3095826.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESDLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2771..2923
                     /locus_tag="VQ878_001504"
     CDS             2771..2923
                     /locus_tag="VQ878_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3095827.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2946..4151
                     /locus_tag="VQ878_001505"
     CDS             2946..4151
                     /locus_tag="VQ878_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET3095828.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            4194..4415
                     /locus_tag="VQ878_001506"
     CDS             4194..4415
                     /locus_tag="VQ878_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095829.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4532..5029
                     /locus_tag="VQ878_001507"
     CDS             4532..5029
                     /locus_tag="VQ878_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET3095830.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            5004..5510
                     /locus_tag="VQ878_001508"
     CDS             5004..5510
                     /locus_tag="VQ878_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3095831.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAEKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5494..7941
                     /locus_tag="VQ878_001509"
     CDS             5494..7941
                     /locus_tag="VQ878_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3095832.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7944..10121
                     /locus_tag="VQ878_001510"
     CDS             7944..10121
                     /locus_tag="VQ878_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3095833.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            10118..11119
                     /locus_tag="VQ878_001511"
     CDS             10118..11119
                     /locus_tag="VQ878_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3095834.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            11116..12051
                     /locus_tag="VQ878_001512"
     CDS             11116..12051
                     /locus_tag="VQ878_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3095835.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            12296..12412
                     /locus_tag="VQ878_001513"
     CDS             12296..12412
                     /locus_tag="VQ878_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3095836.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ878_001514"
     CDS             12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ878_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3095837.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14466..14633
                     /locus_tag="VQ878_001515"
     CDS             14466..14633
                     /locus_tag="VQ878_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3095838.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14693..15046)
                     /locus_tag="VQ878_001516"
     CDS             complement(14693..15046)
                     /locus_tag="VQ878_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3095839.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15551..15973
                     /locus_tag="VQ878_001517"
     CDS             15551..15973
                     /locus_tag="VQ878_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3095840.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15970..16200
                     /locus_tag="VQ878_001518"
     CDS             15970..16200
                     /locus_tag="VQ878_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3095841.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            16661..16864
                     /locus_tag="VQ878_001519"
     CDS             16661..16864
                     /locus_tag="VQ878_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3095842.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16946..18163
                     /locus_tag="VQ878_001520"
     CDS             16946..18163
                     /locus_tag="VQ878_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3095843.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(18325..18927)
                     /locus_tag="VQ878_001521"
     CDS             complement(18325..18927)
                     /locus_tag="VQ878_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3095844.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQIIYGASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLFNKNKV"
     gene            complement(18930..19163)
                     /locus_tag="VQ878_001522"
     CDS             complement(18930..19163)
                     /locus_tag="VQ878_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3095845.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(19176..19556)
                     /locus_tag="VQ878_001523"
     CDS             complement(19176..19556)
                     /locus_tag="VQ878_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095846.1"
                     /translation="MIDLYLSKNNHRNQLLLEFFQNYGIEVSCHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(19549..19998)
                     /locus_tag="VQ878_001524"
     CDS             complement(19549..19998)
                     /locus_tag="VQ878_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095847.1"
                     /translation="MKALNKESILYCDELETELHDAEMMQLDEQIFLMPNYPCEFEVT
                     FLDYYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFIDDNHNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSNLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(19982..>20054)
                     /locus_tag="VQ878_001525"
     CDS             complement(19982..>20054)
                     /locus_tag="VQ878_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HET3095848.1"
                     /translation="TVPVIAAIAKKLKEIEEKDESAK"
BASE COUNT         6568 a         3628 c         4055 g         5803 t
ORIGIN      
        1 agtctggtaa cgataaactc cgtgtctgtt agaaaattct cacacacgtc ttgtgccagt
       61 tgcccttcac agggaaatac tctcagtccc tacttacaca ggcacgctaa tcaagacgga
      121 gtggattcaa ttttcaaaga acaggtagct ttattataga gaagagtagt tgaaattttt
      181 atcacatttt ttatttttct gtagagctaa attcatacta aacaaagatt ttgaaataaa
      241 agactaacat tgttacataa cgttagcatt tcatttccct aaaataagct aattttgtct
      301 aaaaaatagc ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa
      361 ggtcaaaacc actcaattta ctactaattt actacttatg aatgagcttt gatacgacga
      421 tttatccttg aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg
      481 tagacacttc aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt
      541 atgaaaacaa aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat
      601 tcattcagcc aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc
      661 caacatggaa aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg
      721 aagaatcaac ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca
      781 aagagcagat gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt
      841 tgaggaacgt gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac
      901 tcgtggtttt acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag
      961 aggaaaaatg atgagattag caaatggcat tgtattagat aaagacacga cttttggaga
     1021 attgaaattc tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc
     1081 agatgaaatc aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca
     1141 agtaagtatt cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact
     1201 tatcaatccc attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg
     1261 gtatatcaag gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc
     1321 acaagcaaag aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc
     1381 gcatgaaaca gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta
     1441 cgatagcgtc actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa
     1501 tccagcagat caactggcag gattttaacc tatcacaagc agataagatt gacattccct
     1561 atttaattat cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca
     1621 aacgggttcg ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga
     1681 tacttgaaaa caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata
     1741 gtgctggtcg tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa
     1801 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
     1861 acttggaaaa gaaattagag agtgacttgt actgtgagct gacggataaa gagttaaagg
     1921 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
     1981 aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
     2041 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
     2101 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
     2161 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
     2221 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
     2281 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
     2341 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
     2401 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
     2461 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
     2521 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
     2581 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
     2641 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
     2701 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
     2761 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
     2821 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
     2881 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
     2941 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac
     3001 gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt
     3061 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt
     3121 gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa
     3181 ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac
     3241 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
     3301 gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag
     3361 gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt
     3421 tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
     3481 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
     3541 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
     3601 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
     3661 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
     3721 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
     3781 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
     3841 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
     3901 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
     3961 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
     4021 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
     4081 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
     4141 caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt
     4201 ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa
     4261 tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt
     4321 taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt
     4381 tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat
     4441 aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt
     4501 ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa
     4561 tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt
     4621 tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga
     4681 ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg
     4741 ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca
     4801 tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg
     4861 tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt
     4921 accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc
     4981 aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta
     5041 cattactact ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt
     5101 atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa
     5161 aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga
     5221 catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca
     5281 tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt
     5341 ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg
     5401 cactgcgacc aaagctgacc tatgcagaaa aaaaagtaac gcttggcaga aaccagccac
     5461 aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa
     5521 aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac
     5581 aattactcat ttctaagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt
     5641 atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata
     5701 cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat
     5761 gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac
     5821 taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt
     5881 cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg
     5941 atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gttttcagaa gatggaaaag
     6001 ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc
     6061 ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac
     6121 catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag
     6181 cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa
     6241 accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc
     6301 tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat
     6361 gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg
     6421 aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa
     6481 gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac
     6541 aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt
     6601 aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat
     6661 atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt
     6721 caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca aatgctgggg
     6781 gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa
     6841 cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt
     6901 gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg
     6961 ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa
     7021 accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac
     7081 aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct
     7141 attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc
     7201 cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt
     7261 gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt
     7321 tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc
     7381 agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa
     7441 acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt
     7501 agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta
     7561 gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt
     7621 cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc
     7681 ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt
     7741 aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag
     7801 aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc
     7861 ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca
     7921 cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact
     7981 ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca
     8041 tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg
     8101 tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg
     8161 tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca
     8221 tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg
     8281 cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt
     8341 ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg
     8401 gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata
     8461 cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg
     8521 tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa aaaatcaatg
     8581 acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc
     8641 attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac
     8701 aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta
     8761 ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc gaagacagag
     8821 aaaaaattgt tgcggaagaa attgaagaca gaagcaatac caatctaacc attacaaaga
     8881 ccattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg atttccatat
     8941 ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc atctatgcta
     9001 tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt atgtcaaaac
     9061 gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca ttgattatta
     9121 cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat ccgttctttt
     9181 tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg ggcgatttaa
     9241 tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa
     9301 aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt ggacgttcca
     9361 tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag tcgggttcgg
     9421 ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa aaatcaacac
     9481 ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac agaatggtag
     9541 acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca agatatgcag
     9601 tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt agtatttctc
     9661 aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg cgaaaaacca
     9721 ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct gcttcttctg
     9781 ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc tcaaaacagt
     9841 ctaatattca gacttcatat aaggaatctc aacaagccaa acaagagcgt ccagcagtta
     9901 agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg
     9961 ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt ccaatcacaa
    10021 aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt agaccaccaa
    10081 tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa ctttagtgat
    10141 tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg ccattttatt
    10201 ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga atgtttccgc
    10261 agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga
    10321 atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg cggaagatgt
    10381 tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag aagaatccat
    10441 taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc tcagtgtaga
    10501 tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt atgtggctaa
    10561 tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg
    10621 cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct ggcgatacaa
    10681 ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa cagagtttga
    10741 tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct ggcgatacgt
    10801 ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac aatggacgta
    10861 tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg tgacccagca
    10921 tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta cctataacgc
    10981 tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt ttcatgcagg
    11041 cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt tagtgggagc
    11101 aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa aaatcagaat
    11161 aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt caatcctcat
    11221 aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt tgcgatattc
    11281 aagcacttta cagctataga tactcatact attcacgaaa caactatcat agaaaaggaa
    11341 tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt ctactattca
    11401 tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg ctatctgaca
    11461 gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt atcgtcttct
    11521 gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt taatgtaacc
    11581 tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca ctctgcttat
    11641 atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa tccgaccatt
    11701 accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga ggggacggtt
    11761 gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa gctctatcct
    11821 acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa accaatcgga
    11881 aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga taatcaagtc
    11941 acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca ggtatctcaa
    12001 tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata acaaatattg
    12061 gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat tggagattcc
    12121 tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga gttaataaat
    12181 atgcggcaag gtattcttaa ataaactgtc aatttgatag tggaaacaaa taattggatg
    12241 tcctttttta ggagggctta gttttttgta cccagtttaa gaataccttt atcatgtgat
    12301 tctaaagtat ccggagaata tctgtatgct ttgtatgcct atggttatgc ataaaaatcc
    12361 cagtgataag agtatttatc actgggattt ttatgccctt ttgggctttt gaatggagga
    12421 aaatcacatg aaaattatta atattggagt tttagctcat gttgatgcgg gaaaaactac
    12481 cttaacagaa agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacag
    12541 aggtacaacg aaaacggata atacgctttt agaacgtcag agaggaatta caattcagac
    12601 ggcgataacc tcttttcagt ggaaaaatac taagataaac atcatagaca cgccaggaca
    12661 tatggatttt ttagcagaag tatatcgttc attatcagta ttagatgggg caattctact
    12721 gatttctgca aaagatggcg tacaagcaca aactcgtata ttgtttcatg cacttaggaa
    12781 aataggtatt cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc
    12841 aacggtttat caggatatta aagagaaact ttctgcggaa attgtaatca aacagaaggt
    12901 agaactgcat cctaatatgc gtgtaatgaa ctttaccgaa tctgaacaat gggatatggt
    12961 aatagaagga aatgattacc ttttggagaa atatacgtct gggaaattat tggaagcatt
    13021 agaactcgaa caagaggaaa gcataagatt tcataattgt tccctgttcc ctgtttatca
    13081 cggaagtgca aaaaacaata tagggattga taaccttata gaagtgatta cgaataaatt
    13141 ttattcatca acacatcgag gtcagtctga actttgcgga aaagttttca aaattgagta
    13201 ttcggaaaaa agacagcgtc ttgcatatat acgtctttat agtggcgtac tgcatttgcg
    13261 agattcggtt agaatatcgg aaaaggaaaa aataaaaatt acagaaatgt atacttcaat
    13321 aaatggtgaa ttatgtaaaa tcgataaggc ttattccggg gaaattgtta ttttgcagaa
    13381 tgagtttttg aagttaaata gtgttcttgg agatacaaag ctattgccac agagagagag
    13441 aattgaaaat cccctccctc tgctgcaaac gactgttgaa ccgagcaaac ctcaacaaag
    13501 ggaaatgtta cttgatgcac ttttagaaat ctccgacagt gacccgcttc tgcgatatta
    13561 tgtggattct gcgacacatg aaatcatact ttctttctta gggaaagtac aaatggaagt
    13621 gacttgtgct ctgctgcaag aaaagtatca tgtggagata gaaataaaag agcctacagt
    13681 catttatatg gaaagaccgt taaaaaaagc agagtatacc attcacatcg aagttccacc
    13741 gaatcctttc tgggcttcca ttggtctatc tgtagcaccg cttccattag ggagcggagt
    13801 acagtatgag agctcggttt ctcttggata cttaaatcaa tcgtttcaaa atgcagttat
    13861 ggaggggata cgctatggct gtgaacaagg attgtatggt tggaatgtga cggactgtaa
    13921 aatctgtttt aagtatggct tatactatag ccctgttagt accccagcag attttcggat
    13981 gcttgctcct attgtattgg aacaagtctt aaaaaaagct ggaacagaat tgttagagcc
    14041 atatcttagt tttaaaattt atgcgccaca ggaatatctt tcacgagcat acaacgatgc
    14101 tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa aataatgagg tcattcttag
    14161 tggagaaatc cctgctcggt gtattcaaga atatcgtagt gatttaactt cctttacaaa
    14221 tggacgtagt gtttgtttaa cagagttaaa agggtaccat gttactaccg gtgaacctgt
    14281 ttgccagccc cgtcgtccaa atagtcggat agataaagta cgatatatgt tcaataaaat
    14341 aacttagtgt attttatgtt gttatataaa tatggtttct tgttaaataa gatgaaatat
    14401 tttttaataa agatttgaat taaagtgtaa aggaggagat agttattata aactacaagt
    14461 ggatattgtg tcctgtatgt ggaaataaaa cacgattaaa gataagggaa gatactgaat
    14521 taaaaaaatt ccccctctat tgtccgaaat gcagacaaga aaatttaatt gaaataaagc
    14581 agttcaaagt aactgtgatt acagagccag acgcaaagac gcagagccga taaaatgaga
    14641 ttaatacaat ctcattttat cggctctttc cgttatgtat ggattctttt aattagtctt
    14701 cgatgtttct tgcttcgttg ataccgctgg ctaaagattc cattaaggat agttctttgt
    14761 ctgtaaagct atccatgtat ttctctatct gtaatcgtcg ggtgcttttt accaagttat
    14821 tagcaggtaa gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa
    14881 cttgtatgct ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt
    14941 caatcaatgc tcccacttgt tcacgagtta aacctcgttt caatcgagct tctttaatgg
    15001 ctaaaccaaa ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct
    15061 atacatttta ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt
    15121 ataggtttat atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt
    15181 agtgctattt acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt
    15241 caacgtcgcc atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa
    15301 aaaagtcgtc tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata
    15361 gatagaataa cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta
    15421 ttcagaactt ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg
    15481 ggactaagag tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg
    15541 ggtgagaaac atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat
    15601 ctgtaaacgt gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc
    15661 aaagcgtgag gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac
    15721 agataactat tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga
    15781 aaatgatttg ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact
    15841 gctgttttac tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg
    15901 ttctactgtc tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga
    15961 atttgaagaa tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca
    16021 gatggcgata ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag
    16081 cgttccctac gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc
    16141 ttacgtggaa gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa
    16201 tatcctctct cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt
    16261 ttgttattcc accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt
    16321 gttctttgaa aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga
    16381 actaaccgcc atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa
    16441 gcaatcttta gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac
    16501 agtcaatagt ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc
    16561 atgcaggggt ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact
    16621 tttatgaaat ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc
    16681 tatttgggaa cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga
    16741 aaacaagcta cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg
    16801 caatcgtatt cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat
    16861 ctagcgtcgc caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt
    16921 tccataaagg aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat
    16981 cttaaagact ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc
    17041 atttggagaa ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc
    17101 aggaaagcgt gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca
    17161 tgatggtatt gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa
    17221 cgctcaaaga ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat
    17281 tttgaagaaa gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa
    17341 agaatgggct attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa
    17401 acgttcttta aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc
    17461 atttgacttt caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac
    17521 agaagaacag gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa
    17581 ttatgatgaa attctgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt
    17641 gacacttcca gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag
    17701 agatactgaa attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt
    17761 tcctatggtt gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga
    17821 taagcgtgtt gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc
    17881 aaaagtggca agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta
    17941 taacgaggat aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa
    18001 ctatgcaaat gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat
    18061 agccatgacg ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa
    18121 acgcttgaat aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta
    18181 ctacttattt accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt
    18241 atcttcctac agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga
    18301 aaatataaaa agataattag aaatttatac tttgttttta ttaaaaagca gcaaactata
    18361 aactagtagg ttccacacta aatgtagccc catactgccc cacaagtccg atttatagcg
    18421 taccatccct aaaaacattc ccaatgaaac atataaacac caagctagaa tggttcctgg
    18481 atgatgagct aaggcaaata aaacacttgt caaagcaact cgaatatcta attttctaac
    18541 caagttccat aaaatttctc tatacaaaaa ttcttcaacc atactcgcat tgattaagaa
    18601 caataaaaat gaaaaccaag gaacttgatg ttgaagccca attaagtttg cttgatttgt
    18661 gctttcttga gcatgaatca gactaaaata tagactgata atcagtaggc taacgaatcc
    18721 aataccaatc cactttatcc tagtttccat attgaccttg gccacttgtt ttcgttgacc
    18781 atacatccat aaaaaagaaa tgagcgacgc tccatagata atctgtagta tagttaactc
    18841 accgatacaa agaaatttca gtaagtataa ggataccaat aggacattta cttgttggaa
    18901 tatataaact ggaattattc ttttcatagt tacctccgaa ataaatcttc ataatctaaa
    18961 tctaatacct gcacaatcct ctctacccat ggactttgag gcattcgttg ttccatcttg
    19021 tagtgacgaa tcttttgata caaacgattc aattcacttg gatagtgaaa ctctcccgca
    19081 aacatttttc tggttaactc aatccagctg atatttcttt cagccaaaat aatggacaag
    19141 ttctcccaaa atcgttcagc catattgctt ctcctttagt tagataaata atgtgtttgt
    19201 gccatgtaaa tcaattgttt cgtatctctt ggtaataaag ccctagcttc ctccaaattt
    19261 agatttggat aaactcgctt atttgaaacc gcaagaggaa gtctgatggt tagttcagga
    19321 ttttttaata tcatttcaat gaaatccgtt agtcttaaat tgtcacggtt cttaaatcgt
    19381 aataaattag gagataaaaa ctcaaaacaa tctgaagaat agctcatcat ctcaattaat
    19441 ttatcccttg tcatttcaga aatcgaatga caggatacct caatgccata gttttggaag
    19501 aattctaaaa gaagttgatt tctatggtta tttttactta gatagagatc aatcatgtga
    19561 gacctcccaa agattcggtt ccatttgata ttctgagacg attaaggaat ctaataaatt
    19621 ggagaagtta attgatttct tgtcttcatc ataagctttt acagttactt gggttgtaag
    19681 tattccctct tttccctcgg ctcgatagcc ttgcccatat aaaacaaaaa caagattatg
    19741 attatcatct ataaaggcat cagctccgtt ctttatatcc tgactttcaa ggaattccat
    19801 aatgttttga agataggatt cgtaaaatag ggggtaattg tgttttttat ggtaataatc
    19861 taaaaatgtc acctcaaact cacatggata attgggcatc aaaaatattt gttcatccaa
    19921 ctgcatcatt tctgcatcat gtaattctgt ttctaattca tcacaatata gtattgactc
    19981 tttatttagc gctttcatct ttttcctcta tttcttttaa tttttttgcg attgcggcaa
    20041 tcacaggaac agtt
//
LOCUS       DAVBOM010000040        18494 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBOM010000040 DAVBOM010000000
VERSION     DAVBOM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.040"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(1..349)
                     /locus_tag="VQ878_001526"
                     /pseudo
     CDS             complement(1..349)
                     /locus_tag="VQ878_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(425..859)
                     /locus_tag="VQ878_001527"
     CDS             complement(425..859)
                     /locus_tag="VQ878_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3095849.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(935..1785)
                     /gene="rfbD"
                     /locus_tag="VQ878_001528"
                     /pseudo
     CDS             complement(935..1785)
                     /gene="rfbD"
                     /locus_tag="VQ878_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1851..2900)
                     /gene="rfbB"
                     /locus_tag="VQ878_001529"
     CDS             complement(1851..2900)
                     /gene="rfbB"
                     /locus_tag="VQ878_001529"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET3095850.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2910..3506)
                     /locus_tag="VQ878_001530"
     CDS             complement(2910..3506)
                     /locus_tag="VQ878_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET3095851.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3507..4364)
                     /gene="rfbA"
                     /locus_tag="VQ878_001531"
     CDS             complement(3507..4364)
                     /gene="rfbA"
                     /locus_tag="VQ878_001531"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET3095852.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKVYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
     gene            4578..5884
                     /locus_tag="VQ878_001532"
                     /pseudo
     CDS             4578..5884
                     /locus_tag="VQ878_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6172..6354)
                     /locus_tag="VQ878_001533"
     CDS             complement(6172..6354)
                     /locus_tag="VQ878_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095853.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(6570..7802)
                     /locus_tag="VQ878_001534"
     CDS             complement(6570..7802)
                     /locus_tag="VQ878_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3095854.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(7831..8901)
                     /gene="gla"
                     /locus_tag="VQ878_001535"
     CDS             complement(7831..8901)
                     /gene="gla"
                     /locus_tag="VQ878_001535"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET3095855.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(8969..10138)
                     /locus_tag="VQ878_001536"
     CDS             complement(8969..10138)
                     /locus_tag="VQ878_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET3095856.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(10324..11628)
                     /locus_tag="VQ878_001537"
     CDS             complement(10324..11628)
                     /locus_tag="VQ878_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET3095857.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(11745..12899)
                     /locus_tag="VQ878_001538"
     CDS             complement(11745..12899)
                     /locus_tag="VQ878_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3095858.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(12896..13447)
                     /locus_tag="VQ878_001539"
     CDS             complement(12896..13447)
                     /locus_tag="VQ878_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET3095859.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(13440..14576)
                     /locus_tag="VQ878_001540"
     CDS             complement(13440..14576)
                     /locus_tag="VQ878_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3095860.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(14717..15382)
                     /gene="cpsD"
                     /locus_tag="VQ878_001541"
     CDS             complement(14717..15382)
                     /gene="cpsD"
                     /locus_tag="VQ878_001541"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET3095861.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDIQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(15392..16084)
                     /gene="cpsC"
                     /locus_tag="VQ878_001542"
     CDS             complement(15392..16084)
                     /gene="cpsC"
                     /locus_tag="VQ878_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET3095862.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(16093..16824)
                     /locus_tag="VQ878_001543"
     CDS             complement(16093..16824)
                     /locus_tag="VQ878_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET3095863.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(16826..18271)
                     /locus_tag="VQ878_001544"
     CDS             complement(16826..18271)
                     /locus_tag="VQ878_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3095864.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         5956 a         3777 c         2702 g         6059 t
ORIGIN      
        1 ctttcaaaat agtcttaaag gtttcttcat acttgaggct gtattcaatt gcccttccta
       61 gttttgaacc tgctaaaact gactgacgcc ggcaccaagc aaagaagtct tccattaggg
      121 gctggagatg ttcttgacgt ttctgtagtc gttcatcagc tggcaaagcc tcccagtctc
      181 tttccaagga aaataactga tcacaataag ctaaaccttt agctcctaag gatgatttat
      241 ccgtttgctt ggggggcgct tcaaaaaact tccttctcac atgtgcccaa catccaacaa
      301 gttcagcttc ttccagttga cgataagctt ctagcggttc gcagtttacc aagcttagcg
      361 tcgccttgct cctaaacctt ggactgctat cgcataggca gaactagagg actaaagtcc
      421 taagttactg ccgcaacata tcacaatgca catagccaga ataatctcct aggaattctt
      481 gtactactaa accactccga cgctgatcat ggtggtacag cgtgattgct tgattctcag
      541 ctttcccaga caaaaaagtc caatagtagg tcagatggct atcactctct agaacccgat
      601 aagaggtttc atccgcatga agaagaggtt gttctaacaa cttttctcgt aaaaggttat
      661 aaagggactc taaatagtat tgacttgcct tgatatgcca attagagatt tccttacgtg
      721 tgattggtaa acccatccta gcccaatctt cttcttggcg ataattgggt accttcagat
      781 taaacttctg atggatggtg tgagcgataa tagaaactga gccaaagcta tgcaccaaag
      841 agaccagcac caacaacaag ataattgtac atcttaagct cctttggagt tcattatctg
      901 cctcttttat tagactagaa aatcattcta ctacttatct cacttcttgt ttgtaaaatt
      961 cttgcaatgc atcttgccaa gttggaataa caaatccagt agctttggct ttggccaggc
     1021 tcatcgttga gtttagcgga cgttgagctt tggctggaaa ttgactggat ctactggctt
     1081 gacttcgaca tctgtatctt tcaaaatttc aactgcaaaa tcataccatg ttgtgtcttc
     1141 tgtcgcatca tttgacaaat gataataacc aaattcctta cgattttcag ctaggtagat
     1201 catgaattca gccaaggtac gagtccaagt cggacgaccg tactggtcat ttacaactgt
     1261 taaagtctta tgagttttcg caagattttg catggtaaaa acgaagtttt tgccataatt
     1321 tccaaatacc caggcagtac ggataatata gaaattagac acatgcttct caactaactc
     1381 ttcccccata cgcttagtgc gtccatattc tgtctgtgga tctggtcggt catcaacttc
     1441 ccactcttgt ccaactggtt tcttaccgtc aaagacctag tccgtagaaa tataaactag
     1501 agttgcacca tgcttttcag atgcttttgc gacatttttt gtccccatca cattgatggc
     1561 gaagtccaac tcttttcctt catcctctgc tgcatcaaca gcggtgtagg ctgcacaatg
     1621 gtagactaaa gtcggtttca cctcttcaaa aactttctca accatttctt cattggtaat
     1681 gtccatctca gccacatcta ctgccacgta ttcttcatta cgttcatcca ataaatagcg
     1741 aagttccgtt cctaattggc catttgcccc tgtaattaaa atcatctcta gacctttcta
     1801 atatgtaact cttcccaata tagcaataaa aagcagcgat ttcctgcttt ttatactgta
     1861 ataatctcct gagtcttagc ataattggct tcaacagctt ctttttctgc tttccaccat
     1921 tcttggttat ctgtatacca cttgattgtt gccttgagcc cagcttcaaa gttggtaaat
     1981 tcaggtttcc accccaactc atcacggagc ttgctggcat caatcgcata gcgaaggtca
     2041 tgtcctgcac ggtcagtcac atgatcatag gcatccgtag cttgtcccat ttccttaagg
     2101 ataagttcca aaacttcctt attgttcttc tcaccatcag ccccaatcaa gtaggtttca
     2161 ccgatttgcc cttttgtcaa gattgtccaa actcctgaag aatggtcatt ggtatgaatc
     2221 cagtcacgaa cgttcttacc ttcaccgtaa agttttggct taattccact taggatgtta
     2281 gtaatctgac gtgggatgaa tttttcgata tgttgataag gaccgtagtt atttgaacag
     2341 ttggaaatcg ttgccttgac tccaaaagaa cgcacccagg ctttgacaat caagtctgat
     2401 gcggccttgg ttgatgagta cggagagctt gggttgtatt ttgtttcagc agtaaatttc
     2461 tcacctggtc cttcaccatg acctggcaaa tcttctcgta aagggagatc cccataaact
     2521 tcatctgtcg atacatggtg gaagcgaata tcatacttac gagcagcttc taaaagagta
     2581 tagattccaa tgaagttagt atgaataaat ggcgatggat cattgagcga attatcattg
     2641 tggctttccg ctgcataatg aacgatagca tctgcttgag caaccaactt gtctaccaac
     2701 tccgcatcag caatgtcacc aacaactaac tcaacacgat tgcctaaaat ttcctcaata
     2761 ttcgcgcggt ttccagcata agtcaactta tctaggactg tcacgtgaac atctggaaag
     2821 ttctcgtaaa cataatggac aaagttagaa ccgataaagc cagctccacc tgtcacgata
     2881 atatttttgt attcagtcat attctttcct tattccaaat cttctttttt caaaggcttc
     2941 acgtccttaa gtaggggatg atgtttgtct gcttcagata cgtctgcttc ttccagattt
     3001 tcccattcaa taccaaggct tggatcagcg tagttcacaa aggcatactt gggtttgagt
     3061 tcaagagccc agtaatcatt gaccagatag ctatatgaca ctgtatctga taaaacttgg
     3121 aagccattag ctacgcctcg aggaacaaag attcccttgc ttgcatcaat tactgtctga
     3181 taggtattcc caaaggtttc accctcgcgt agatcaaccc aagaacccag aactttccct
     3241 ccatctgcta cagagatgta cttatcccaa ggctctgcgt ggaggcctcg aaggacattt
     3301 ttacgtgaga aggatacatt gttttgcaat tttccttctg caaagaaaga ctctggaaat
     3361 ccaagtggaa gcactttttc cttttggaaa ttttctttaa accagccacg attatctcca
     3421 tgaacgggga tatcaaactc caacatgcct ggaatagctt caaccttgcg tgccgcaagc
     3481 gtcttaccga aaaaattatc tgtcatctat gcttctccaa tcaaacggag cagatactgt
     3541 ccgtattcat ttttcttaag tggttgggct aaggccaata catcttctcg actgatatag
     3601 cccatacggt aagcaatttc ttctaagttt gctacctgaa cattttgcat ccgttgcact
     3661 gtttcgatgt actgtgaagc ctctagtaaa ctttcatgag ttccagtatt cagccaagca
     3721 aagccacgtc ccataagctc aacagacaaa tcaccacgat ctaggtaaac cttgtttaca
     3781 tctgtaattt ccagttcacc acgagggctt ggtttaatac tcttggcaat ttcgacaaca
     3841 tcgttatcat agaaatacag tcctgtcact gcatagttgg agcgaggata ctccggtttt
     3901 tcttctatgg aaatagcatt catgtctgta tcaaactcaa ccacaccaaa acgctctgga
     3961 tccttcactt ggtagccaaa aacagtcgca cctttctctt tcttggctgc tttttgaagc
     4021 attgtgctca gaccaggacc atggtagata ttgtcgccta aaatcaaggc aacgctatcg
     4081 tcagaaataa actcttcccc aattgccaaa ccatctgtac ttggttgctc tgcataagaa
     4141 agtttgatcc caaactcaga tccgtcttga agaagctctt gaaatcgatg taaatcctgt
     4201 ggagtggaaa taatcaaaat atccctaatc ccagccaaca tcaatgttga aagtgggtag
     4261 taaatcatcg gtttatcata aaccggcata agttgttttg acgcagcgcg agtcaaagga
     4321 tataaacgtg tccccgaacc acctgctaga ataatacctt tcatagtagg gtacctttct
     4381 ttgttatttt agagtcaatt actattaatt gtgtactgct ctaaaaagaa aacaatcatc
     4441 ccatgtttta tatggctcta taatatttgt agtgggtaaa tcccttatag atattatgga
     4501 gcctattttg ttgtagaaaa aaagtcccat atgacctata atgaaaagcg accaaacaac
     4561 tcattagaaa gattcatatg gaacaattac attttatcac aaaactgctc gatattaaag
     4621 acccaaacat caagattcta gatatcatca atatggatac ccacaaagaa attatcgcta
     4681 agctggatta tgaggctcca tcttgccctg attgtggaag tctaatgaag aaatatgact
     4741 ttcaaaaacc gtctaagatc ccttatcttg aaacgactgg tatgcctact agaattctcc
     4801 ttagaaagcg tcgattcaag tgctatcact gttcaaaaat gatggtcgct gaaacttcta
     4861 tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca aaagattgct caaaagttaa
     4921 ttgaaaagat ttctatgact gatattgccc atcagctttc catctcaact tcaactgtta
     4981 ttcgtaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
     5041 cttgggatga gtatgctttt acaaagggaa agatgagctt cattgcgcaa gattttaaca
     5101 atctcaatat catcactgtt cttgagggta gaacacaagc tatcattcga aatcactttc
     5161 ttcgctacga tagagttgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
     5221 cttactatga cttggctaaa cagtttcgct ttcaaatttc taggctcagg ctgaaacagt
     5281 ctcccagact gtttcactcc cgaatgctaa aatcgtgttg gatcgctttc acattgtaca
     5341 acatcttagc cgtgctatga gtcgtgtgcg tgttcaaatc ataaatcagt ttcatcgaaa
     5401 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaatagg atagtcgtaa
     5461 actgagtgat aaacattttt atcgtcctac ttttcgtatg cattgaacca ataaagagat
     5521 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
     5581 cttgcttttt catttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
     5641 tcttaagcag gttcatccta tttttcagac cgtctttaaa accttcctca aagataaaga
     5701 aaagattgtc aacgcccttc aactacacta ttctaacgcc aaactggaag cgaccaataa
     5761 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
     5821 acggattttc atcgctctga acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc
     5881 ttagctgact tcaacccact acagttgaca aagagcctaa aaattcactt acttcatatt
     5941 acatttagca tgaaatgaaa taagcgaatt ctactttgtt tgcatacaat taaaaatcaa
     6001 ttcctaagga tgttttaaat aactgtgtaa aaggcataat ttcaccattt cttagttttt
     6061 caatgctaaa ttacatagta actggagagc tattagaaat ctctaacttc ctcatagtta
     6121 aaaaatgaca atgagatact tattgatttc aattcattaa cagaatacga actagacaag
     6181 tgagttcgtc tccttaacaa acacttccaa gcgtttactt tcctcattca gtcgtcgtaa
     6241 tctacaactt acatcatcag ataagtcata ctcaccattt agaatagata gaatatgttg
     6301 tttttcttct tcagtcttct cttcaataag cacattttta aaaattactg ccattatcag
     6361 cacctcactt cgaaggaata tatgcaacta tatcctatta agtcaatctc tactgacaaa
     6421 agaagtatat ttacttcact aagtgcgagc gagaatatag aaatatcttt attgttttag
     6481 atgagttgtc gctatcctcc agctagtttt taactattct atcattcaaa tgatatagat
     6541 tattagggac tagaaatata caaattgatt taatctctct taaaaatatc cctagtataa
     6601 actttacccc tcacatcttc taaagtctca tcaaaacgat ttgcaacaat cacttgacta
     6661 gatttcttaa atatttcaaa atcattaact acttgactac catagaaagt agtaccactt
     6721 tcaagagttg gttcgtaaat aataatagta acaccttttg ctttcaaacg cttcataata
     6781 ccttgaatag aagattgtct aaaattatct gaattacttt tcattgttaa acgataaatt
     6841 cctacaacaa tctctttttc tttatctggt ttatagaaat cattgcctac ataagatcca
     6901 gcaagatcta aaatacgatc tgcaatataa tcttttcttg tccgattact ttgtactata
     6961 gctgttatca tttcttgtgg aacgtcagaa taatttgcaa gaagttgctt ggtatcttta
     7021 ggaagacagt aacccccata accaaaagaa ggattattgt agtgagaacc tattctcgga
     7081 tctaaacaaa ctccatcaat aatcgcttga gtatctagtc ctttcatctc agaataagta
     7141 tctaactcgt taaaatagga aacccggagg gcaagatagg tattagcaaa aagttttact
     7201 gcttcagctt ctgtaaaatc catatacaat gtttcaatat tttctttcac tgcaccttcc
     7261 tgaagcattt ttacaaaaat ttcagcagac tttaccaaat ctttatcatc tttatctgta
     7321 cctataataa ttcgactcgg atataggtta tcatataacg cttttgactc ccgtaaaaac
     7381 tcaggactaa acataatatt gtctgtaaga aatttcctcc gtactgactt tgtatatcca
     7441 acaggaacag tacttttaat tattataatt gcatcaggat tatatttcat aactgcttca
     7501 atgacagcct cgactgaaga tgtatcgaaa aaattttttt tcggatcata attagttgga
     7561 gccgcaataa ctataaaatc cgcattctca tatgcttcct ctgcattcaa tgtagctacg
     7621 agattcaatt ctttttccgc gagatatttt tctatataat cgtcttggat aggggacttc
     7681 tttttattga ttaactcaac tttctcagga atgatatcta cggcaacaac ttgatgatgt
     7741 tgagccagta agattgcaat agataatcca acatatcctg tacctgctac tgctattttc
     7801 ataatttttt cctttctcaa aacactctcg ttatacatta tagtagtctt tataccactc
     7861 tgcaaacttt ctcaaacctt ctcgtaaaga agtttttggt ttaaaaccaa aatctctctc
     7921 taaatcactt gtatctgcat aagtaacagg aacatcgcct ggttgcatag gaactaattt
     7981 tttatgacta tcaaaatcat aattttccgg caaaactcct gccttgatta gctcctgttg
     8041 aagaacatcc acaaaatcta acaaattttc gggtttacta ttcccaatat tgtacacttt
     8101 atatggggct aacggtaaat tatcagatcc cactagtttc ttcggagctg attgcatgac
     8161 ccttactatc ccctcaacga tatcatctat ataagtaaaa tctcgtttac aattaccatg
     8221 attataaatc tcaatatcgg aaccacttcg caatttatct gtaaatccaa aataggccat
     8281 atctgggcgc ccagcaggac cataaactgt aaaaaagcgt aagcctgtcg aaggaatatt
     8341 gtaaatcttt gaataagcat acgcttgaag ttcatttgtt tttttagtcg cagcatatag
     8401 tgaaatagga ttgtctacct tatcttctgt tgcaaacggg atttttttat ttccaccata
     8461 taccgatgag gacgatgcat aaactaagtg ttccacacca ccatcatata tctcatacga
     8521 atgacgacaa gcttccaaca cattatgaaa gccaacgata ttactttcta tatatacatc
     8581 tggatttgta atggagtagc gtactcctgc ctgggcagct agattaacaa caatctgagg
     8641 atgataactc ttaaaaatct tattaataag cattttatct gcaatatcac ccttgataaa
     8701 tatccagttt ttttctggat aatcctgaat tagcttatta agttgaagca atcgataatc
     8761 tttaagtgca atatcatagt aatcattcaa attgtccaaa ccaatgattg tcatcgttcc
     8821 ttctaattcc aataatttcc taaccagatt tgatccaata aaaccagcta ctcctgtaat
     8881 tagaattgtt tttcctctca tatcataata cctcttgtta tttttatatt ttcatccact
     8941 aatacacatt ctttaacaac tattataatc aatttctaag ataatctata ataaaaaaca
     9001 aaccacatac agtataagag attgctgatg ctatcgcagc tcctgtaatt tggtagttag
     9061 gaattaagta ccagtttaaa cttatattta tcaaagccga cacagataaa atttttatag
     9121 ctacactctg tttaccctga gatatataaa ttggttgtaa aattttaaag aaaatcatcg
     9181 ataagcttcc taaaaaaatg actaatgtta taggaaatgc ctttatataa ctggaaccat
     9241 aaaggagcgt aatcgcaaat tctccaaaag aaagaaatcc aataattaat aaaatcataa
     9301 atagaaatga tacttttatt gcatttattg ctttattttt ctcaaaagtt cttttagccg
     9361 aatcaccaaa taaaatctct ttaaatgagt ctggaaccat caaaaacata ttagaaaacg
     9421 taactgcgac actgtatata cctacattat aactactaga catttgcttc aacattatga
     9481 tatcaatact ataattaaat gtaattaata gagtaagaat catagaaaga aatccaaact
     9541 tatatatagt gaaaaattct ttaatactaa tatgttcaaa aactgggaac atattgtaat
     9601 agtataaaaa taaaatgata cgtaaaaatt cattaatagc atataccaaa aataccatct
     9661 ctatagaaac taaatgaaat agtaacaaca atactagcat aacggaatat actacgctta
     9721 ctcctaatac aatcttattc ctctttatac tattttctat tactgcaatc atagtaagat
     9781 ttgttctcat aatagataga ctggacaaaa ctattattac cccaccataa tctatcggaa
     9841 catcagctaa aactattatt aaacctatta ttccaaacaa taatccttga ataaaagtta
     9901 aaaaaacaaa tttattctga tactcattag aatgattcct tttaaaggtc gagtaagcct
     9961 gacctaaacc aactccacct aaaatataaa aaatttctac taagttcatt acataggcat
    10021 aatctccttt tttttcaaca cctaatcccc tattaattat aattgaggat aaaagtgtta
    10081 ataagattaa caaaaattta ctcgttaaag caaaccaata tttcttagat agtctcactt
    10141 attttctccg tatgttaaat tttataacag taaatttaaa attatagtat attgaaatag
    10201 aatatgaaca aaacgattag ggaatttaaa gtaatttata aaaattcttt agaagctgca
    10261 ttgtactact ccaacttcaa accactatag tatcaaaaag tataccccac ctttttaaat
    10321 aaactactca ccacccattt catccaatgg tgatatcaac accattctat tgataaaaac
    10381 aataaccaat gttcccaata tagcatattt aagtaatgga gataatatgt tagcaaaatc
    10441 agcacgagta gaataaataa aaataggtat catatacaga tatatcagca tcccgtatat
    10501 atttctttga gcgtttatat aaagaaatct catcaaaaag cctgttagca taaaaatcat
    10561 tacaattcca aagtatcctc cattcacata tccctctccc acaagagtaa aaccatattt
    10621 ggttgaatgt acgtttggaa aaaaggtgtc cataaaccaa gtttgattag aataccccgt
    10681 attataaaaa attcttacta tgtcattaaa aaaagaacga ccttcgaaat aattgcccat
    10741 attatgtaat atcagaatct gtaaattacg actagctgat acaaactcac catctagcaa
    10801 atcaaaccaa atattatttg tatttataga tgaaacttgc ccacttaata aagtatattt
    10861 aaaaactgca gataacggaa tcagtagtgc cgcaagcgga actaacatta caagataaaa
    10921 acgttttatt ttgtgaaagt aaaataatat aatcacatca aggatgaata aagtaaacat
    10981 ataatctctt tcccctgtaa cgatagagaa gagacagata actatcgctg tgttagtatt
    11041 acaatttagt agtctccatt ttttagtact caactgtata aatagctgat atgtatgaat
    11101 gagaatcata aaataaacca aagaaaatac taacattatc acaatattgg cacctgaata
    11161 tatttcccct ttatttctaa aaccacttcc taatagatat ataattgcta ctgttgtgat
    11221 aaacgtattc atattattga gaaataataa atagttattg ttatttaggt ttattttcct
    11281 ttcgcttaac acaatggctt tagaaggtag agttaacaac aaagttgcca aagccagcca
    11341 ttgcatgaaa atcaaatctt ttgtataacc atagtttata tactccattc tatagagtag
    11401 cgggtaagaa atagaataaa tagtaaagaa gctactatac cacacatagg gatgaaaaat
    11461 attaaatttc acaattatca ttgccataaa acttaaaaaa atcattgaaa ataatggaat
    11521 tgtaacatca ttattttcac tgcataaaat taaagtccct gaaaaaacta cacctactag
    11581 aagtattatt ttatttttta tatcatttga ttgtagacta aacttcattt acttttttcc
    11641 tttaactaat aatttaaacg taatgcgtat tcaaaaattt gattggctat gtagtcagtt
    11701 tttatagcat atttaatata tcgaaacgga ttttccatcg cattttaatc taaaccatca
    11761 gaattattta attctcttct aatttgagca aaatagtcac ttctgcgttt atttaataca
    11821 ctcgaaagaa atttttttga gaattcaaac tgttttatca ccatcttttc cttatccata
    11881 ctaataaaat ctataataga tcccgcaatc gcttgtgaag aggatggagt aaatagacaa
    11941 tgtggcccca gcaactctgg aattcctgct ttattagacc ctatacaagg gcaagcacgg
    12001 ctcatagctt caattaccgc acgaggtaac ccttcttgta aacttggttg tatatataaa
    12061 tcaactttat ccaaatactc ataaatttgt gatgtagtca attcccctaa aaaatggatt
    12121 ctattcgcta ctcccaattc ctctgctttc ttttttaaga aactttgatc accatcacct
    12181 gctaaataat aatccaacaa aataccttgt atttctaatc tcttcattgc ttccaataca
    12241 aatctatggc ccttggctcg tacattcaca gatgctgttg tcattattga aattttttga
    12301 ggattaaatt ttttcaactt ataaagacgg ctcttcaaag atctattctc tacagaggta
    12361 atattaacat ttgaagcaac gatattagat ttaatattag gatatctatc ttgtaaatat
    12421 ttttctgtca cgtatatgca ataattagcg ttttttacaa ttgatttagt tttggcgtat
    12481 atatatggag ctaataattt tccctttaaa ctatgatacc agtaagaatc ccaagcatcc
    12541 cccattattt ctgtcagata cggcttacct atcttcaatg cgtagtctgc agtttttgat
    12601 ccaattatag acggaatacg aacaactatt aagtcgctat caatcattcc ttcaataatc
    12661 ttatttttat tttgaccaaa tagaacctga tgtagacctt ctatagggat aaatttatta
    12721 ataaagttcg ctttatgata tccttcaggg tatgattcca ccttctcata acgactacat
    12781 agtacaatct ctccaaatgc tttagcatag cgctcataaa taaaataagc tttcggtttt
    12841 aaatatattt catttttata gattgtacat ctaaattcag tcgctataaa tactttcata
    12901 atttcatctc ccttgataaa cgtttctgaa taaatatagt atcagctgga atatcctttg
    12961 ttacaacact tcctgctgca accacactat tctcaccaat actcactccc ttcaagacaa
    13021 tgctgttagc tccaatccaa acattttctc caatcataac tggggccgtc ttaaattttt
    13081 ttgctttcaa tccacctgga acactaacat catagtcatg atcatatata agtactccag
    13141 gaccacattt tactccagat ttaatatcta tgtatttacg acaagctatc atacaattat
    13201 tactcaaaaa tacatcatca gaaatcttga gttttgctcc ttttctaact ttcaatactc
    13261 ccccggcgtt tactctaatc ttttttccta agattaattt agcattagat tcctgttcga
    13321 cagttacatt ctttccaaat tttaaaaaat aatgaaaagt aagatccttg tttcgacaca
    13381 cttttaataa tatcaagcaa atatttgcac gaagtaaacc aacaatattt tttataatcc
    13441 tattcatcta aagctccttt tattttatct aaataagcat ctataataat ttgacgagaa
    13501 aaatattgct ctatatacat tctcccttga agtcccatct cttttcgttt ttcattttct
    13561 agacctaaaa aaacttccaa tatagagact agttcctcaa catttccccc ttgaaatata
    13621 tagcctgtct ctctatcttt aacaatttct ttgcaacctg gattatctgt cgtaattaaa
    13681 acacgtcctg aactagcgtt ttctagtaat acattgctca ttccttcacc atacacactg
    13741 ggatggataa ttgcatggga acgggtaata tgaggtatca catctttttg ttgtcccaaa
    13801 taataaacga ttcctttttt ttctaagtca caaattttaa gttcataatt actctctgtc
    13861 ggttctataa agccaataat attaaactct gttttgggat atcgactctt aataatttgg
    13921 gcagcagcca gataagtatc tatacctttt tcttttaata tcctaccaat aaaattaaaa
    13981 acgattgttt ctccttgaat tccatttcca ccatttggat actgttgcac aggatacttt
    14041 tcaatgttca ctcctgaccc aggtatcagc ttagagtcac ccaaaatcaa gccaagagtt
    14101 tttaacattt tcatattata ttcattttga aaaaaaacac aatttgattt cctaaaagaa
    14161 attctaaaca gtaataacac caggcttctt acacaagaac ccattgttaa gacactacct
    14221 aaacctgtta cgttatttat atattttatt cctaaaattg ttgcagctag gctagcatat
    14281 acatttggtt tcacggtata tgtcaagact acatccggtc tatattttct caataatctt
    14341 atataactaa gaaatagacg aatatctttt aaagggttta ttcctcttct atcaatagta
    14401 atatcttcat actcaaattg aatagacttc atcagctcta tcttatctcc ataaggacat
    14461 gacactagca cttcataccc atactcaact agtgactcta taacttcttt tcgaaaacaa
    14521 tagatatcat cgtcatgatt agttattaac ataatttttt tcttttgtaa attcatcaaa
    14581 ataatcttcc taaaatataa ttaaccgcta ctccattatc ctttacaact atcattttaa
    14641 aaatagtaat tttctataag taattgtttc caaattgtga cactttaaaa ttctatacac
    14701 atatagaact tacaaactat ttacgaccgt aaactccata cttatcaacc gagatatcca
    14761 atttatttaa aacaactccc aggaacagtt tccctgtttg ttctaattgt tgtttcgctt
    14821 tttggatatc acgtttattc gcctcacctg ttgctgttat caagatggac gcatcacact
    14881 tttgagtgat aattgccgca tcaataacaa ttccaatagg tggtgtatca acaatgatat
    14941 aatcaaaata tttacgcaat gtttcaatca tatcattaaa atttttactt tgtaacaagg
    15001 ctgtagggtt tggtgataca gatcccgatt gaactacaaa taaattttca atatttgtat
    15061 cacataaacc gtgagataaa tcagctgtcc cagataaaaa ttctgttagc cctgtaattt
    15121 tttcacgaga tttaaaaaat cctgacataa ctgaatttcg aatatcgcca tcgaacaaaa
    15181 gagttttata gcctgcacgc gcaaatgaca ttgctatatt tacggaagta gttgtttttc
    15241 cttcccccgg attaacagaa gtaacggaaa ttacttttag tttatctccg ctcaactgta
    15301 tatttgtaca caaggtattg taatattctt ctgccttctt aatgaactcc agtttttttt
    15361 gtgctatttc taatgtcggc atctctctct cctatttcaa cttacccaag tttggtacaa
    15421 ctcccaaaag tgtcatctgc agtgcatttt cgatatcttc cggacgtttc acacgagtgt
    15481 ccaaaagttc aagaagaaga actataacac tagttccaat cacccctgcc aaaaaaccaa
    15541 ttagtgtatt gcgtttaata tttggcgaag acggtgatat cgccggtctt gcctcctcca
    15601 gtgttgtcac atcagaaaca cgagtaatac tgataatttt ttgagcagct acttctctta
    15661 aagagttagc gatacggctt gcctcttcag gaactcgatc actaactgaa acagagacaa
    15721 tacgggtatc aactggtact gttactttaa ttttattagc caaacctttt ggcatcaaat
    15781 ctagtttcaa atcagaaata acttcctcca aaacatcctg cgataggaca atttcacgat
    15841 agtctttaac caagtatgct cctgcctgca agtcttgatt ggttaaacca ggcttctctc
    15901 cctgattacg gttaactaca taaatccgag tcgtactagt aaactcaggt ttgataacaa
    15961 aagtactgta ggcaaaagca actgaagaag ttataattgc cactaataaa atgaccaact
    16021 ttcttttcca taaagctctg aatagttgca atacatcgat ttccaaagtg ttttgttcct
    16081 tcatattttc tcctaaatta attgatccat tataattttt ctgggattat ctacaaaaag
    16141 ttctttcgct tttttcgctc catatttctt agcaatgata tcatatgcct gttgcatata
    16201 tggaggtcta ctgtctaaat tgtgcatgtc acttgcaact acatgaacta aatcacgttc
    16261 caaaaaatac cgagctctct ttttcatgaa tttatatttt tcaccaaaga acttaggttt
    16321 tgaaacatga taactattta tctgagtata gcaccccata tcaatcagtt cacgaacacg
    16381 tttttcgtta ttctctaaag catcataacg ttcaatatga gcaattactg gcgtgattcc
    16441 caacatcaaa atattgctca atcccgtatg aatctgacga taggaagtat gcatgctaaa
    16501 ctcaatcaag gcataacgac tatcattaag ggtaggaatt tctttttttt ctagcttttc
    16561 tagagcatcc agagtatagt atatctctgc gccataagca atgactaaat catctgctac
    16621 ttcttttgca atttcccgaa cctgaagaaa gttttctgct atcttctctt ccggagtttc
    16681 aaacatgccc ttgcgacggt gagaggtaga gacaatggtt ctcaccccct gcctgtagga
    16741 ttctgccaag agagccttgc tttcctctct tgacttggga ccatcatcta catcaaagac
    16801 gatgtgcgaa tggatgtcta tcattttatc taccctccat cacatcctgt atagctgctt
    16861 taactacagt taaactacta tcatctattt ccatcacata gaggttactg tctggcattg
    16921 cataagaagg aagatccatc cgacctgtcc cttttaaatc ttgagaattt actttataat
    16981 tccctccact ttccaactga gtattcacta aatctatcat agtctcaatc ggtatatttg
    17041 tttgaagaga atcctgcaat ccttgaagaa tactactata gtttttcaaa acctctgtag
    17101 aagttaactt ctgaataatt gctacaatga ccttttgttg gttgcgacca cggtcacggt
    17161 ctccatcggt tagtgagtag cgttcacgta caaaacctaa agcttgctca gagtctagat
    17221 ggacattccc tactgggaaa tggaacttcc catgtagagc tgaaaactct tgatcattat
    17281 gaacatctac ccctcccaat aagtcaatca ttttcaagaa agaagtgaag ttcaatcgca
    17341 catagtaatt gatatccact ccatagagat tttctaaggt gtgaatggac gaatcaactc
    17401 cataaatgcc cgcatgggtt aatttatctt tttgattatt tccactatct gcgattggta
    17461 cataggcatc acgtggcgtt gtggtcaaga ggattttctt ggtatctcga ttgacagtca
    17521 ttaggatatt gacatctgat cgcgacaccg aactaatagg accataggtg tcaattccac
    17581 taacatagat attgaaagac tgattcttag acgtcttagg agcctctact tttttagtga
    17641 atcccttggt ataaatcttt tttatcttcg atgcgtagtc tggatactct gactcgatga
    17701 tattttcaaa gacactattt aggacaatgg ccttagtctc ccctgcaatc aaactcttgt
    17761 aagctgccaa gtaagacgaa ctctggttga ccgtcaaatc ggtattctga cttgacttga
    17821 tatcagctag tagtttttga atattttcat tatcagtccc agtcggtgct gtcacactcg
    17881 tcagttgcgt aacattttcg atcttactat ctgctaaaac agcgacactg attgaatatt
    17941 ctgagtaatt agaagtcgca tttaaacgat tggtcagtcc aacaaactgc tgtactgcaa
    18001 agagcgacac tgagctgaca aggatagaga acagcaacag aaaaatagta aacttttcag
    18061 cttttttata gataatcaag agtagcccta ccaaggcaac tagtaggact aacgcagtta
    18121 ccactaggtt aagatatcta aaagcaagga tattgtactt aaagattaag aacaataaaa
    18181 aacaaattaa caataaataa atagtcagca aaacgatatt aacacttcgc ttcactttct
    18241 gtgaacgtga ttttttaaaa cgtctactca tgattaacac ctataccttg aacatcatac
    18301 aattatatca cttttttacg gtaatgtcta cacctttatt ttcactatct gcatctttaa
    18361 gtatcttagt agacttcccg cgaaccaaaa atatagtaaa atgaaataag aataggacaa
    18421 atcaatcagg acagtcaaat cgatttctaa caatgtttta gaatcagatg tgtactattc
    18481 tagtttcaat ataa
//
LOCUS       DAVBOM010000041        18308 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBOM010000041 DAVBOM010000000
VERSION     DAVBOM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.041"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            166..480
                     /locus_tag="VQ878_001545"
                     /pseudo
     CDS             166..480
                     /locus_tag="VQ878_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            657..1316
                     /locus_tag="VQ878_001546"
     CDS             657..1316
                     /locus_tag="VQ878_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET3095865.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1341..2408
                     /locus_tag="VQ878_001547"
     CDS             1341..2408
                     /locus_tag="VQ878_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3095866.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2511..3521
                     /locus_tag="VQ878_001548"
     CDS             2511..3521
                     /locus_tag="VQ878_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095867.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3533..5224
                     /locus_tag="VQ878_001549"
     CDS             3533..5224
                     /locus_tag="VQ878_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3095868.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5227..5937
                     /locus_tag="VQ878_001550"
     CDS             5227..5937
                     /locus_tag="VQ878_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET3095869.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6033..6224
                     /locus_tag="VQ878_001551"
     CDS             6033..6224
                     /locus_tag="VQ878_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095870.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            6509..7510
                     /locus_tag="VQ878_001552"
     CDS             6509..7510
                     /locus_tag="VQ878_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3095871.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            8651..10012
                     /gene="trpE"
                     /locus_tag="VQ878_001553"
     CDS             8651..10012
                     /gene="trpE"
                     /locus_tag="VQ878_001553"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET3095872.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            10009..10575
                     /locus_tag="VQ878_001554"
     CDS             10009..10575
                     /locus_tag="VQ878_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET3095873.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            10586..11590
                     /gene="trpD"
                     /locus_tag="VQ878_001555"
     CDS             10586..11590
                     /gene="trpD"
                     /locus_tag="VQ878_001555"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET3095874.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            11587..12354
                     /gene="trpC"
                     /locus_tag="VQ878_001556"
     CDS             11587..12354
                     /gene="trpC"
                     /locus_tag="VQ878_001556"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET3095875.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            12341..12940
                     /locus_tag="VQ878_001557"
     CDS             12341..12940
                     /locus_tag="VQ878_001557"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET3095876.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            12918..14141
                     /gene="trpB"
                     /locus_tag="VQ878_001558"
     CDS             12918..14141
                     /gene="trpB"
                     /locus_tag="VQ878_001558"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET3095877.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            14134..14910
                     /locus_tag="VQ878_001559"
     CDS             14134..14910
                     /locus_tag="VQ878_001559"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET3095878.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14882..14983)
                     /locus_tag="VQ878_001560"
                     /pseudo
     CDS             complement(14882..14983)
                     /locus_tag="VQ878_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            15212..15352
                     /locus_tag="VQ878_001561"
     CDS             15212..15352
                     /locus_tag="VQ878_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095879.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            15389..15943
                     /locus_tag="VQ878_001562"
     CDS             15389..15943
                     /locus_tag="VQ878_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095880.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            15958..17109
                     /locus_tag="VQ878_001563"
     CDS             15958..17109
                     /locus_tag="VQ878_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3095881.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(17161..17820)
                     /locus_tag="VQ878_001564"
     CDS             complement(17161..17820)
                     /locus_tag="VQ878_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET3095882.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            17890..>18308
                     /locus_tag="VQ878_001565"
     CDS             17890..>18308
                     /locus_tag="VQ878_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095883.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVR"
BASE COUNT         5903 a         2959 c         3937 g         5509 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgctt ttatatttgc taaactttca gaaaaaaagt
       61 tggagtatat gatgctaggt gactgcgtca tgttaataaa cgaaatggaa ataactgatc
      121 atagagtaga taacttattt gaaaaaggga aaaatgagat aaaagatcca tgtagtagat
      181 ttagcaatag gacatataaa agctttagaa aaagtatctg aaaaaacaga tgtttatatc
      241 tataacctag gctcgggaga aggcactagt gtattacaac ttgtaaatac atttgaaagt
      301 gttaataaga tccctattcc ttataaaata gttccaagac gttcaggaga cgttgcaatt
      361 tgttatgcaa atgcagacaa agcatataag gaattaaatt ggaggacaac aaaatcgatt
      421 gaagacatgt gtagagatac atggaattgg caatcaaaaa atcccaatga ctataattga
      481 tgatactgtc tatatgagtg ctgtattttg gaaaaattac ttaacctttt aatgaaatgc
      541 atatttaatg aaagataaat aaaaaaagtt tgacagcgct tgacaaagga aacggtttca
      601 ttgtataatg taaacatggt gacaccgatg tcaaatataa aaaagaaggt ctttatatga
      661 aaaacttaac aaaaattaag ttcaaagaga atggggaatt taatcatttc tctgggaata
      721 cagttgtagc aaatctttat actaaacaag atttgatgga agttgttgat attattcaat
      781 cacgttatag agaattacca tttatcgata agtttacttt aactccaagg aattctattc
      841 acatgactgt aattgaattg ttgtgccatg aaaatcgtga aacggagttt tggagcagta
      901 atcttcctct agatacacct ttacaggaaa tacatgatta ctttgctaaa caacttgaaa
      961 tttttccatt gttggatgaa gaaattcata tgcgtataac tgaaatggga aaacaaaaca
     1021 tactagttga acctgcagat gaagcttctg caaagagatt agaagaaatt cgtacttatg
     1081 tctcagaaaa agcaggtgtt tgtttcccta atcatgatag atatcaattc catatttcaa
     1141 ttgggtatct tcggattcct ctaaccgaag aggaggaaga agagtttact aaagtcagag
     1201 cagaattaac tgaaatttta ttagagaaga ttccaactat tactgtaaac cgtattgact
     1261 atactgtatt tgaagatatg agacaatttg ttccatatca cgaaaaattt aaataaaata
     1321 ataaaaaagg agaacttatc atgaaaaaaa tgaaagtttg gtctactgta cttgcaacgg
     1381 gagttgctct tactacactt gctgcttgct ctggaggttc aaattctacg actgcttctt
     1441 catctgaaga aaaagctgat aaaagtcaag aattagtaat ctattcgaac tcagtctcaa
     1501 atggtcgtgg tgattggtta actgctaaag caaaagaagc tggttttaat ataaaaatgg
     1561 ttgatatcgc tggcgctcaa ttagcagacc gtgttattgc tgagaagaat aatgcagttg
     1621 cagatatggt atttggaatt ggtgctgttg actcaaataa aattagagat caaaaattac
     1681 tagtacagta caagcctaaa tggttagata aaattgatca atctttatca gataaagata
     1741 attattataa tcctgtgatt gttcaaccat tagttttaat tggggcgcct gatgtaaaag
     1801 aaatgcctaa agattggact gaattaggta gtaagtataa aggtaaatat tcaatttatg
     1861 gtcttcaagg tggtacagga cgggcaattc tagcaagtat cttagttcgt taccttgatg
     1921 aaaaaggaga tttaggcgta tcagaaaaag gatgggaagt tgcaaaagaa tactttgcaa
     1981 atgcctatac tcttcaaaaa ggtgaaagct cagttgttaa agcgttagat aaagaaagcc
     2041 caattcaata cggtatgatc tggggttctg gagcgttaat cggacaaaaa gaacaaaatg
     2101 ttgaattcaa agttatgact cctgagattg gtgtaccatt tgtaactgaa caaactatgg
     2161 ttttaagcac tagtaaaaaa caagcgttag ctaaagaatt tattgattgg tttggtcaat
     2221 cagaaattca agtagaatat agtaaaaaat ttggctctat ccctgccaat aaagatgccc
     2281 taaaagagtt acctgaagat acgaaaaaat ttgttgatca agtgaaacca caaaatattg
     2341 actgggaagc tgttggaaag catttggatg aatgggtaga aaaagctgaa ttagaatacg
     2401 tacaataaga aataagagtt attttttatg tccaagtctc tctattattt ctaaatttat
     2461 ggaagaaata aagagaggct tttggtttag taatagaggg agttagtgag atgattaaat
     2521 ttgataatat tcaaattaaa tatggtgatt ttgttgcaat tgataatctg aatttagata
     2581 tacatgaagg ggaattcttt acatttcttg ggccttcagg atgtggtaaa tcaactactt
     2641 tgagagcatt ggtaggtttt ttagatccat catcaggaag tattgaagtt aatggaacag
     2701 atgtcactca tttggaacct gaaaagcgtg gaattggtat tgtatttcaa tcttatgcgc
     2761 tatttccaac tatgactgtt tttgataata ttgcatttgg tttaaaagtt aagaaggtag
     2821 ctccagatgt tattaaagct aaagtatcag cagtggcagc aaaaattaag atctctgatc
     2881 aacagttaca gcgtaatgta tcagaattat ctgggggtca acaacaaagg gtagcattgg
     2941 ctcgtgctct ggttcttgaa cctaaaattc tttgtctaga tgaaccattg tcaaaccttg
     3001 acgcaaaatt acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa gagttaggta
     3061 ttactacttt atatgttact catgatcaag aggaagcctt gactttatct gatagaattg
     3121 cagtctttaa caatggatac atcgaacagg tcggtacacc agtagagatt tatcataatt
     3181 ctcaaactga atttgtatgt gattttattg gagatattaa tgttttgacc gatgaaacag
     3241 tccacgaagt attactgaaa aatacaagcg ttttcttaga agataaaaaa ggatacattc
     3301 gattagagaa agttcgattc aatcgtgaaa ctgaacaaga tttcattcta aaagggacaa
     3361 ttattgatgt tgagttttct ggagttacaa ttcactatac aataaaagtt tctgaaagtc
     3421 agattcttaa tgtaacaagt attgatagtc aggctgctat tagatctgtc ggagaaagtg
     3481 tggaattatt tatcacacca tcagacgttc tgcaatttta aggaggtgca gtatgcgtca
     3541 taaattaaat ttaaaagatt ggcttattcg tttagggtta atctggttct tagtaacatt
     3601 tattatttat ccaaactttg atctagtagt gaatgtattt gtaaaaggag gagaattttc
     3661 ccttgatgct gtacatcgtg ttctaaaatc tcagagggca cttcagagta ttatgaacag
     3721 ttttaagtta gcattttcac tcattattac agttaatgtc gtaggtattc tttgtgttct
     3781 atttacagag tactttgata ttaaaggtgc taaaatttta aaattaggtt atatgacctc
     3841 tttaatttat ggaggagtgg ttttagcgac tggatataaa tttgtctatg gtccttatgg
     3901 attgattaca aaatttttac aaaatgttat cccttcttta gactctaact ggtttattgg
     3961 gtatggtgca gtcttattca ttatgacatt ttcaggaact gctaatcata cattgttttt
     4021 aacaaataca attcgaagcg ttgactatca cactattgag gctgctcgaa atatgggagc
     4081 aaaaccattt actgttttcc gaaaagtagt gttaccaacc ttaattccaa ctctatttgc
     4141 acttactatt atggtttttc ttagtggttt atctgcagta gcagcaccca tgattgttgg
     4201 tggtaaagaa tttcaaacta taaatccaat gattattaca tttgcaggga tggggaattc
     4261 tcgtgattta gctgccttac ttgcaattat tttaggtatt gcaactacaa ttttgcttac
     4321 tatcatgaat aagatagaaa aaggtggaaa ttatatttct atctctaaga ctaaagcgcc
     4381 tcttaaaaaa caaaaaattg cgtctaagcc ttggaatatc attgctcaca ttgtagcata
     4441 tggattgttc acagttttca tgcttccact aatttttata gtattatact catttacaga
     4501 tccagttgca attcaaacag gtaacttaac attatcaaac tttactttag aaaattatcg
     4561 cttattcttt agtaatagtg cggcattctc tccattcttg gtcagcttta tttattctat
     4621 tattgctgcg acaacagcaa caattctcgc agttgtattt gctcgtgttg tcagaaaaca
     4681 taaatctcgt tttgatttct tatttgaata tggtgctcta cttccttggt tactaccaag
     4741 tacactttta gcagtaagtt tattatttac ttttaatcag ccacaatttc ttgtcttgaa
     4801 tcagattttg gtaggtagtt tggtaattct acttattgca tatatagttg taaaaatccc
     4861 attttcttat agaatggtac gtgctatttt atttagtgtt gatgatgaga tggaagatgc
     4921 agcaagaagt atgggtgctt caccttttta tactatgatg aaggttatca ttccatttat
     4981 tttaccggtt gttctctctg ttattgcttt aaactttaac tctttattaa ctgacttcga
     5041 cttatctgta ttcctttacc atcccctagc tcaaccatta ggtattacga ttcgatctgc
     5101 aggtgatgaa acagcaacat ctaatgcaca agctctggta tttgtttata caattgttct
     5161 gatgattatt tctggaacgg tattatactt cacacaaaga ccggggcgta aagtaaggaa
     5221 ataatcatga cagccactag tcttgggtta tcaaatattg aaatagttgt caggattgtt
     5281 ttatcagtag tcattggtag tataattggt ttagagagag ggagcaaatc ccagcctgca
     5341 ggcatccgaa cttatagtat tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa
     5401 tacgtatctt ataaatttgg gacaggagat cctacacgat taggagctca agttatatca
     5461 ggtgtgggtt ttctaggcgc tggaacgatt cttattacag ataaaaagaa aattacaggt
     5521 ctgacaactg cagcaggcat ttgggcttcg gcaggaattg gattagctat tggagtaggt
     5581 ttttatgagg gagctctttt agtagctatt tctgtttggg gtgtgatatc catgttccaa
     5641 ccactaaaaa aatatctgca aaatcgttct aaaatgattg aattgtatat agtggttaaa
     5701 tctacagaag cctataatcg tgtattggtt tattgtgcag aaaatggtat cagaatgacc
     5761 gattcaagaa cagcgtttgg agatgttaat tctgacagaa ttgaatactt tgatgttcca
     5821 gataaaaaaa tagcgtcatt tattactctg gaattatcag gtagatttga acatcttcga
     5881 ctgatggaag aaattgctaa tattgtaggt gttatttatg tcgaagaaat tagctgaaat
     5941 ttagtaaaca aagggacaga tgtttttgtc cttttgtttt ttagatgttt taatcatcta
     6001 atttttgagt agatttttgc tcagaggttt ttatgaaaga ttataaaatc aattttgatt
     6061 taggtaaaat agaatatttt gataataatt gtttgataca agtatacaaa tttatttctt
     6121 tttatgatat ttgtgaaatg gtgtttgcct ttcatttacc tcctgatgag ttgataacaa
     6181 atgttatctt taaagaaaaa attaactcta tgttaaaatg ttaaattgac aggctattat
     6241 atgtttttat aaatcctaca cattttactg aaaaagttaa tctacaattt tatggtagtt
     6301 ttttctcata tgaatttatt tgtcgtgaag ttggaaacat tcttaaaaat aaaggtgtga
     6361 aatgcaattt aaactttttt gaagggaaag aatatttgta aaattaattt tgtgaatttg
     6421 tggatcttaa ataatttact aaattctctt gttaaaaaaa attaaatatt gtatagtaat
     6481 attagaatgt tcgtaatgga ggactgaaat gaaaaatata aatgggaaaa aggtaactat
     6541 ttatgatatt gcacgtttat caggtttttc tccaaaaaca gtttcacgag ttattaatgg
     6601 tggagtaaat gttaaagaag aaacttatca agcgattcaa aaagttatag aggaattgtc
     6661 gtatattcca aatgcgtatg caaaaaattt aactaaaaaa gaagctataa atatattgat
     6721 ttctgtaaaa aaaatcgact cttttccttt aatttggttt catacgctgt tagataaagt
     6781 gttacggacg tgtaaagaat ttggtgttaa tgctatagtt gagtactttg gagaggagga
     6841 tacaattagt aattcaatta tatcaagcac aggtagccta gtagatggtg ttattgtttt
     6901 ttatgaaagt gtagatgata tcagaattca gtatttaaag aagaaccata tgccttttct
     6961 tgttttcggt gaatctcaaa cgtctggagt agtctatgta tctaataata attttcaagc
     7021 tacttatgat atgatgaaag ctgtaactga agaaaaattt aaaaatatgt ggttgcttat
     7081 gggaggagaa tcccatgtta ataaggatcg tgaaagaggt gtgcgttctt ttctgaatga
     7141 taaaaattac tttatggatt taaaagtcat ttatggctta tctacaattg attcagttta
     7201 ttcttatgca atgcagcact tgactaccca aaattatccg gacattattt ttgtttcagg
     7261 agatgaaaag gttcaaggct tgattcgtgc gtgctatgag aaaggaattc ttattccaga
     7321 tgatatttct atcattggat ttgataatat tcctatttct cagtattata ctccagcttt
     7381 gtctacaatt gctcccaatt atgttaaatt ggctaaagaa atgatagaag gtgttttagc
     7441 aattattaaa ggggaaagtg tcacatctgt tgaagtttct cctaaatttg ttaggagaca
     7501 gagtttctag tattgtttaa ttcttgaaaa tcctagtgga aaagatggag tgttctaaaa
     7561 taagttctgt ttagcctcca ttcagtttct attgagttgg atccaatttc taacgagtgg
     7621 gacatgttca tgttcgatct aaggaagaca tggtcacatt cgaatgatat tttcaaaaaa
     7681 atcgtaaaaa agtcttgaca aagaaaaaac aaagtattaa aataagttca acaaatcaga
     7741 aaagtaacta tttttgatct tcagggagcc tgtggtgatt gtgaataggt ggttggaagt
     7801 agtgaaagtg ggctgatttt gaaaatgaat ttgaaacaat gaaaattcgg tgcgcacacc
     7861 ttacagtgca gcttgttgtt aaacaaggca gagatgtaaa gggatagtcc ctttataatt
     7921 gaggtggcac cgcgttacca acgccctcac acggaagtat attctgtgtg tgggcttttt
     7981 tctatccgtc gtttgcttta tcttttatta gggccttaac tcgctttgat gaacttgagt
     8041 tctatctaca gctccttgcc tcctactaaa agtaaacaaa aaggctggac taatacgaaa
     8101 aaagctagta atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct
     8161 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaaccat acctacgata
     8221 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta ccgagatgaa
     8281 catctcttca tcaatgtctc tggtcgtgga ggcaaggacc tagctgcgat tgcagattac
     8341 tagaagctaa aaaataatag atggaaaaat tacagtcttt tctctcacag agagcttgtg
     8401 gttgctgaaa acaagcagag aaagctgtaa agttgggttc atctgaaacg agagaagaaa
     8461 acatcattct caagggagtg ccctttatcg cacagcctgt tacaggaggt atctgagaca
     8521 ggaatgagag ataggagaaa tcctataatt gaggtggcac cgcgaatttc gtcctcacgc
     8581 aagttatttt gcgtggggat ttttcataca gtcgccacga actagaatta gaactgaaag
     8641 ggaaattaca atggaacgaa tcattcatgg agatgtctta tcaccaatct tggcttatat
     8701 gcgcttaaag gggcaacata aggttatttt agagagtatt ccgagagaca aggaaacggc
     8761 tcgtttttct atcctagcct ataatccagt ttttgagatt aagtttgaaa atggagttct
     8821 ctatcaaaat ggtcaagtga ttgatcggga tcccttggat ttcctttatg aagtgattca
     8881 taagagtcag caccattcag agctcccttt tggtggtgga gccattggtt ttgtgggtta
     8941 cgatatgatt tcgctttatg aagaaattgg tcaaatccct gaggatacaa ttgggacgcc
     9001 agacatgcat ttctttgtct atgagagcta tatggtcttt gaccacaaga aggagaagat
     9061 acatgtcata gaggatgcac tttatagtga gcgcagtcaa gaggccttgg aaaaatcctt
     9121 gaaccaagtg cttgaggaat tacgcattcc tgctccaaat gaatttgaag acttggattt
     9181 atcaccactt gacttcaaac cgcatatcgc tccacataag tttgagggaa tggtagaaac
     9241 agctcgtgac ttgattcgta acggtgatat gttccaatgc gtactcagcc agcgcttctc
     9301 agcagaggtt actggaaatc catttgactt ctacagaaat ctccgcgtga ctaatccttc
     9361 taattacctt tatttctatg attttgggga ttatcaaatc atcggagcca gtccagaaag
     9421 tttggtttct gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga cgcgaccaag
     9481 aggggctacg gatgaagaag acaaggcctt ggcgactgac ctcctctctg atgagaagga
     9541 aacagcagag catcgaatgt tagtagacct gggtcgtaat gatattggtc gcatctctga
     9601 aacgaccagt gtccaagtca ctaagtatat ggaagtggag ctcttccgtt atgttatgca
     9661 tctgaccagc gtggtcaagg ggcgtttgct tccagaactc actgccatgg atgccttgaa
     9721 agctacactt cctgctggaa ccgtttctgg agcaccaaag attcgtgcta tgagacgtat
     9781 ctatgaactg gaaacagaaa aacggggcgt atacgcagga gcaatcggct acttgtctgc
     9841 gacgggtgat atggatttgg ccattgccat ccgaaccatg attctcaaaa atcaaagagc
     9901 ctatgtgcag gctggggcag ggattgtcta cgactctatc gcccaaaacg aataccaaga
     9961 aaccattaac aaagcaaaat ctatgactag aattggagaa ctaagaccat gattttattg
    10021 attgacaact atgattcttt tacctataac ttggcccaat acattgggaa ttttgcagaa
    10081 gttcaggttc tgagaaatga tgattccaag ctgtatgaag aagctgaaaa agcagatggt
    10141 ctggtctttt ctcctggtcc tggttggcca gttgatgctg gaaagatgga agacatgatt
    10201 cgtgactttg caggcaagaa gccgattcta gggatttgtt taggccacca agccattgca
    10261 gaagtctttg gtggtaagct aggtttggct ccaaaagtca tgcatgggaa acagagcaat
    10321 atcaactttg aagcgccatc tgttttgtat caaggtattg aggatgaccg tgcggtcatg
    10381 cgttatcaca gtattttgat tgaggaaatg ccagaagact ttgaagtgac agctcgttcg
    10441 actgatgacc aagccatcat ggggattcaa cataaaaacc taccgattta tggcttccag
    10501 taccatccag agagcattgg aacgccagac ggcttgtctt ctattcggaa ttttatcgag
    10561 aaggttgtaa agtgaggaaa ctaggatgaa agagattatt gaaaaactag caaaatttga
    10621 aaatttatca ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg ggcgtgtaac
    10681 tgaagcgcag attgcttctc tcctcttagc tcttaagatg aagggggaaa cacctgaaga
    10741 acgcacagcc attgcccgag tcatgagagg acatgcccag catattccaa ctgagattca
    10801 tgatgctatg gacaactgtg gtacaggtgg ggacaagtct ttcagtttta atatttccac
    10861 aactgcagcc tttgtcttgg ctggtggcgg tattcacatg gccaagcatg gtaaccgctc
    10921 gatttcttct aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca atcttgacct
    10981 caaaccagct gaactaggta aggtctttga taaaactggc atcgtctttc tcttcgctaa
    11041 aaatatgcac ccagctatga aatacatcat gccagctcgt ttggaattgg gaattccaac
    11101 gattatgaac ttgactggtc cactgattca tccaatggct ttagaaacac agcttcttgg
    11161 aattagtcgt ccagaactcc tagaaagtac agctcaggtt ttgaaaaata tgggtcgcaa
    11221 acgtgccatc gtggttgctg gaccagaagg gttggatgaa gctggcttga acggaacaac
    11281 caagattgca cttcttgaaa atggcgaaat cagcttgtca agctttactc cagaggattt
    11341 gggaatggaa ggctatgcta tggaagatat tcgtggtggg aatgctcagg aaaatgcaga
    11401 aattttgctt agcgttctga aaaacgaagc aagtccattc ttggaaacga cagtcttgaa
    11461 tgctggtctt ggtttctatg ctaatggtaa gattgatagc atcaaggaag gagttgcctt
    11521 ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt tacaggagta
    11581 ccaaaaatga gtcaggaatt tttagcacga atcttggagc agaaggcgcg tgaggtggag
    11641 cagatgaagc tggagcaaat ccagcctctg cgccagacct atcgcttggc agaatttttg
    11701 aagaatcatc aggaccgctt gcaggtaatc gctgaggtca agaaagctag ccctagtttg
    11761 ggagatatca atctcgatgt ggatattgtg caacaggccc agacttatga agaaaacgga
    11821 gcagtgatga tttcggtgtt gacagatgag gttttcttta aagggcattt ggattatcta
    11881 cgggaaattt ccagtcaggt agagattccg acgctcaaca aagactttat catagatgaa
    11941 aagcaaatca tccgcgctcg caatgcaggt gcgacagtta tcttgcttat tgtggcagcc
    12001 ttgtccgaag aacgcctcaa ggaactgtat gactacgcga cagagcttgg tctggaagtc
    12061 ttagtggaga ctcacaatct agctgaacta gaggtagccc acagacttgg tgctgagatt
    12121 atcggggtca acaaccgcaa cttgactacc tttgaggtcg acttgcagac cagtgtagat
    12181 ttagcccctt actttgagga aggtcgctat tacatttctg aatctgccat tttcacaggg
    12241 caggatgcgg aacgactagc cccatacttt aacggaattt tggtagggac agctcttatg
    12301 caggcagaaa atgtggccca gagaatcaag gagttgcaga ttgacaaagg ttaaaatttg
    12361 tggactatcg accaaagaag cggtggaaac agccgtttca gcaggagccg actatatcgg
    12421 ttttgtcttt gcacctagta aaagacaggt gactttagaa gaggcagctg tgttggcaaa
    12481 gcttattcct gcagatgtga aaaaggttgg agtatttgtt tcaccaagtc gggtagaact
    12541 gctggaagcg attgacaaag ttggcttgga cttggttcaa gttcacggtc aggtggcaga
    12601 tgatttattt gagaatttgc cttgtgccag tattcaggct gtgcaggtag atggaaatgg
    12661 gcatgtcccc aattctcagg cagattatct actctttgat gcccctgtgg caggaagtgg
    12721 ccagcccttt gattggggtc aactggatac gactggacta gcacagccct tctttatcgc
    12781 aggtggcctt aatgaagata atgtagtaaa agcaattcaa cattttactc cctatgcagt
    12841 agatgtatcg agcggagtgg agacagatgg acaaaaagat catgaaaaga ttagaagatt
    12901 tatagagagg gtaaagcatg gcatatcagg aaccaaataa agatggattt tacggaaaat
    12961 tcggcggacg ttttgtccca gaaacattga tgacagcagt tttggagttg gagaaggcct
    13021 accgtgaaag tcaggcagac ccaagtttcc aagaggaatt aaaccagctt ttgcgccagt
    13081 acgtaggacg tgaaactcct ctttattacg caaaaaactt gacccagcat atcggcggag
    13141 ccaagattta tctcaaacgg gaagacctta accatacagg agcccacaag attaacaatg
    13201 ccttaggaca agtttggctt gccaaacgca tgggtaaaaa gaaaattatc gcagaaacgg
    13261 gtgctggtca gcacggtgtg gcaactgcaa ctgctgcggc cctctttaac atggaatgta
    13321 ccatctacat gggtgaggaa gatgtcaaac gccaagccct caatgtcttc cgtatggagc
    13381 ttttgggagc taaggtcgag gccgtgacag atggttcgcg cgtgctcaag gatgcggtca
    13441 atgcagccct tcgttcatgg gtagctaata tcgatgatac ccactatatc cttggttctg
    13501 ccttggggcc tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc atcggtcgag
    13561 aggctaaaca acagtaccgc gatatgacag gtcaagatct gccagatgcc ctagtagcct
    13621 gtgttggtgg tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa gatgagtcag
    13681 tagctatgta tggaactgaa gcagcagggc ttggtgtgga tacagagcac cacgctgcta
    13741 ccttgaccaa gggtcgtccg ggtgttcttc acggttctct catggatgtg ctccaagatg
    13801 cccatggtca aattcttgaa gccttctcta tctcagcagg tttggactat cctggtattg
    13861 gtccagaaca ttctcactac cacgatatca aacgtgccag ctatgtccct gtgacagatg
    13921 aagaagcctt ggaaggattc caactcttgt ctcgtgtgga agggattatc ccagccttgg
    13981 aatctagcca tgctatcgct tttgcggtga aattggccaa agaacttgga ccagaaaagt
    14041 ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc aaagaccgct
    14101 tggaagcaga tgcagcaaag aagggagaag ctcatgccta agacactaac agaaaaattg
    14161 aatgctatta aagcagctgg aaaaggaatt tttgttccct atatcatggc tggtgaccac
    14221 gagaaaggtt tggacggtct tgctgaaaca attcactttt tagaagattt gggtgtctct
    14281 gcaattgaag tgggtattcc cttttcagac cctgttgcag atggacctgt tatcgaagaa
    14341 gctggcttgc gcagtttagc ccacgggacc tctacccagg ctttagttga aaccttgaaa
    14401 accattgaaa cagagattcc actggtcatc atgacctact tcaaccccct ctttcagtac
    14461 ggtgtggaga actttgtcaa agatctggct gatacagctg tgaagggctt gattatccca
    14521 gacttgcctc atgaacatgc caactttgta gaaccatttt tggcagatac agatatcgcc
    14581 ttgattcctt tagtaagctt gaccacagga attgagcgcc agaaagagtt gattgaaggc
    14641 gcggagggat tcgtctatgc cgttgccatc aatggggtga cagggaaatc aggcaattac
    14701 cgtgcagatt tggacaagca cttggcgcaa cttcatcaag tggccgacat cccagtcttg
    14761 acaggttttg gtgtatctag tcaagccgat ctggaacgct tcaatgcggt gtcagatggt
    14821 gttatcgtcg gttcgaaaat agtaaaagct ctccaccaag gagagccgat tcaggatttt
    14881 atcagacaag cagtagctta ccaaaaataa tcaaacaagt agcaagtaag aggaaaggca
    14941 cgaaaggaag tctttccttt ttcttttgca ggcgaaaggc tagttttata gtgaattgaa
    15001 tctggaatat tacactacgg ttcctaaaat attttaagaa agtgatttga atttcccaat
    15061 aaatttgttc agtttttaat tgattttact atagaagata taattttcta aattactctg
    15121 acacagaact ttaagaaaaa gctaattatt gtagtaattt ctttaagaaa atgatataat
    15181 tcattaaaaa gtatttggag gaggaagaat tatgttgaat caggatctct ttgattcgct
    15241 tgaggcacaa aaaattgtag atactttgat gaaagggcaa aaagattatg tagatgaacg
    15301 tctagaaaaa agagagacaa tgatagtgtc gaatggttat gcatggacgt gacctaatca
    15361 tattgatact gcatttgcat cagcagattt gtttgagtat aaattacaat tagcaggaca
    15421 gacttgggga tatttagaat ttgaaacaaa tacagaaaaa tatgggaaag tattgttaat
    15481 tataaagggt aagaagcgac ttacgaacca atttcctttg gtacaaaaaa ataagagtgg
    15541 ctacttattt gaatatgctc agatgaatac actttatctt aatcaacatt cttcctacaa
    15601 aaatgatgaa gatagtcatt cctttccaat tcagatggag ttagtttctg atgaaatgat
    15661 tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa aaatttatga ttttaactta
    15721 tgaggcggac tcagaaaaca atattatatc tgtagatgtt gttatgcctg atgcacgaac
    15781 tggtcagtta cacttgattc aagatttgtc tgagtatatt caatcaagtt cgtaccattt
    15841 cgaagaagct aaatatcaag atattcctaa tttttcagaa ttatcggaaa cagaagattt
    15901 tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag tagtaaggag tatgtaaatg
    15961 tttaatggtc gggtattgaa agaattacgg ctgttaaatg gtttaagtag agcagaatta
    16021 gctcagagaa ttaatttaac ggaacaagcc atttggcagt ttgagtccaa cgaaacgaaa
    16081 cctaaattat caaccaaaat gcatttggcc aaccaatttc atgttgattt aacttatttt
    16141 gaacaggaag aagagagcat tcgatttgat tcttctgtaa ttgcctttag aaatgcagac
    16201 ctagcaacac ggaaaacaat agatattcaa actatgtatt tacataaggt agatagtttg
    16261 attgattatt ttgaaagttt tgtaattata cctaatatta taattcatga cctaagtaat
    16321 gtagtgagtg aatcttatca taagggagaa tccattgagg aattggctct ttatgccagg
    16381 gaaaaattag gtatttcaaa agataatcat gatttgcttt ataaattaga acgttcaggc
    16441 atctatatcg tggaacgatt aattaatggc caagctgatg cttatagcgc atggtcaaaa
    16501 ttgggaagac cttatattgt gttgggaacg aataaatcat ctgtacgtcg aaattttgac
    16561 ttagctcatg agctaggaca tattctttta cataaatata aagatatgaa tgaagatggc
    16621 gatcgtttgg agcaagaagc aaattatttt gcatcatgtt ttttattgcc aaaagaagag
    16681 tttttagtca aatttgaaga gagggttggc aagcgtgtca gcaatcctga tagttatatt
    16741 ttattgaagt cggatttgaa tgtttcgata caggctttag agtatcgagc ttttaagtta
    16801 ggattattga ctccaaagca acattcttac ttttatcgtc aaattgcgca aaaaggttac
    16861 aaaatgattg aacctttgga tgatcaaatt tttgttaaaa aaccaagcaa agtaaagagt
    16921 attctggacg tcgttttgag taatcatcta gtcagtctag cgactataat gtctaaacaa
    16981 agtattcgtt tacagtttat aagcgaaata ttttcagtcg aaatgaaatt ttttgatcag
    17041 tatcaagaag atagaagaac agatcgattt gataacatca tccctttgta caaaagaaat
    17101 aatttataat ttaactgtga aataatttca tgaaggacat atggcagaaa ttggacttta
    17161 tcaaacaagc agtagcttac caaaaataat caaacaagta gcaagtaaga ggaaaggcac
    17221 gaaaggaagt ctttcctttt tcttttgcag gagaaaggct aggatacccg tcgcagaagc
    17281 aaactgaatc aagatcagta actccgttat gctaaagacg agagcacaag aagctaaaaa
    17341 gaggaaatcc cctgcgccca tgcggatatc gataaaatga gccaaaattc caagagcaag
    17401 gaaggagacc atgaccagat tccagccaga ggaagctatt aggattaggt ggaaagtcat
    17461 ccagaccagt aagggatatt cctgatggcg aaagtcatag atgctcaagg tcaaaccagc
    17521 ggtgattagg acgacttgcc ccaaggaaag caattcccaa gagtaaagca gaaagaggag
    17581 tcctaagcct agttcaaaga gggcatacca gacaggatag cggaccttgc agtagcgaca
    17641 gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa tctaagggac gcaagggagt
    17701 ctgacaggaa tcgcagtgac tggctgaact gataatggat tgctctggaa aacggtcaat
    17761 gaccaaacca agaaaggaag cgagaatgct cccgacgaga aaaaaataaa aatcaatcat
    17821 acttatctat tcgtaaaaaa tgggagaaat agtataatgg agaaacatag ataagatggt
    17881 gaggaaaaga tgacaattcg ttttgaagaa aaggtgagta tagaaaacgc tcaatttgta
    17941 tgccaatggt ccaactccct aggcaaatcc tttcaagaac aatggatggg atcaaggatt
    18001 ccttttctac tgacccttca agccttggaa gaagtctttt caatctttga tgaacaagag
    18061 tttgtgggac ttatccagaa aatcaggcta gaagacagca atcttcatat cgggagattt
    18121 tttatcaacc cccagaaaca ggggcaaggc ttaggtagcc aggctttaag gaaatttgtt
    18181 agtttggcct ttgaaaatga agatatagat agtatttctc taaatgtctt cgaggcaaat
    18241 caaagagctc agaatcttta ccaaaaagaa ggatttgaaa tcgttcaaat ggttgaagca
    18301 cctgtacg
//
LOCUS       DAVBOM010000042        18177 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBOM010000042 DAVBOM010000000
VERSION     DAVBOM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.042"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ878_001566"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ878_001566"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET3095884.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ878_001567"
     CDS             complement(863..2125)
                     /locus_tag="VQ878_001567"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET3095885.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVS
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ878_001568"
     CDS             complement(2135..3265)
                     /locus_tag="VQ878_001568"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET3095886.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ878_001569"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ878_001569"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET3095887.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VQ878_001570"
     CDS             complement(5231..6118)
                     /locus_tag="VQ878_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3095888.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVIAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIDHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ878_001571"
     CDS             complement(6108..6569)
                     /locus_tag="VQ878_001571"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET3095889.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ878_001572"
     CDS             complement(6566..7474)
                     /locus_tag="VQ878_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3095890.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ878_001573"
     CDS             7467..7664
                     /locus_tag="VQ878_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3095891.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ878_001574"
     CDS             complement(7716..8387)
                     /locus_tag="VQ878_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3095892.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ878_001575"
     CDS             complement(8441..8662)
                     /locus_tag="VQ878_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET3095893.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ878_001576"
     CDS             8934..9743
                     /locus_tag="VQ878_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3095894.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ878_001577"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ878_001577"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET3095895.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ878_001578"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ878_001578"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET3095896.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGRPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ878_001579"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ878_001579"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET3095897.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGVDDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ878_001580"
     CDS             complement(13018..14277)
                     /locus_tag="VQ878_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET3095898.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ878_001581"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ878_001581"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET3095899.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15390..16105
                     /locus_tag="VQ878_001582"
                     /pseudo
     CDS             15390..16105
                     /locus_tag="VQ878_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(16071..17546)
                     /locus_tag="VQ878_001583"
     CDS             complement(16071..17546)
                     /locus_tag="VQ878_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET3095900.1"
                     /translation="MKEVDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         5332 a         4168 c         3324 g         5353 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcatcc atgaccgttc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggctaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc ccttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgagtgctgt gggattcaat gtgcgaaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaaa tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa cctgctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacga ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagcaacacc agagtctgtc aaatagaacc aacgattgtt ccattttttc
     4081 cattgattct gtaataagat acccgtttgg ttaaagtaat accattcacc cttaatttca
     4141 ttccaaccga cagcatattc tcctgtagaa tcaggcgctt gataccacca gtttccatat
     4201 gaactcttat gccaaccagc ttgaaaactt ggaataggct tgtaggaagt tgaaatgttt
     4261 actaaaccgt cttgtcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaagtcgcc cccaaggtaa
     4561 attttcttgc cattgacttt taccacacta atcaaggaat tggaattatc atcccaaatt
     4621 ttctttaatt cacctgatga atcggtttca ttttcatagt tatagagttg aatatccatg
     4681 tccccaaact gaaaatgagc atctccctgt gtgatgtttt gaataactga aacacctttt
     4741 tctgaagcag tctgtaaaac cttatcataa ccgtacagat tatcccatag acgttcagaa
     4801 ttagtaatac gattatcact atatttttta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatggtca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca gggtttcctt aaaaatttct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggtcgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacatg aaaacgcgtc actgcaggct
     5521 tccctttagc aattacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat tcccggacgc agaaccccat
     5761 tgataccaga caagtcctta atatgataca tgagggcatt gactagagtt ccactagtat
     5821 gaccagcact cggatgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc aagactgcgt gataattctg
     6061 tcaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactggccc tgtcaataaa gtttccaaga ccacccgcga ttatcaaagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaat tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 cacacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg ccaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aaacccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgaag
     9361 aagcgactag tggaaagtta cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccgc ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattct gccccattca gagcaagaca gcgggctgtt
    10321 tcggggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccaac acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa tcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gccttcccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat tgaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgcct caaagccatt tctcaaagat ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tactccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggag cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 ggcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggatcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccaacc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggattgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt tattccctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagtttt ttgtttcaat tggtaatgag tttgataacg
    15301 catagacgtt ttatctcgtc taaggtaaca agacaaaaaa ttcgtggata accaagtaga
    15361 cttgaaatac tacatctgga ggtactccca tgctttatgt gggcattgat gtcgctaaaa
    15421 ataaacacga tgttacagcc ttgaatgttc caggaaaaac tgttcttaaa ccactcactt
    15481 tttcaaataa taaagctggt tttgaactct tagatctgtc tcttcgacaa ctcaaccaag
    15541 actgtctcat cgctcttgaa aataccggac attatgcctt taatctactg aacttcctgc
    15601 atgaacaagg atataaagtt tacacctgca atcctttgct catcaaggaa tttgccaaat
    15661 cattatcact tcgcaagact aaaacggata agaaagacgc tcatggcatc gctcttaaac
    15721 ttctttctga ccccaatcgt gaacaatttc aacacgataa tcggcaagta gaactaaaaa
    15781 tactggctag acatattcat cgtctcaaga aaaacagtct gattggaaag tacaatacac
    15841 tcgttgtctt gatatcatct ttcctgagtt ggataaaatc gttggaaagc attcagaata
    15901 tacctaccaa ctcttgacac gctaccctaa tcctcagaaa aggattgagg caggatttga
    15961 taagctgata gaaattaagc gattgaccgc ttctaattca agggcttttt gccgtgctct
    16021 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
    16081 ttcttatagt ttgtctttct cttaataacg ttgatatgat tgacctctgg atcttccgtc
    16141 ccttggaggg agcaaccacg ttccttggcg aattggatat agtctacaat ttctcgtgta
    16201 atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac aaattctcca
    16261 cagacctgtc caacagactc atctaaggtc aaactttttc tctctgaata gaaggcttct
    16321 tgtggagaca gcaccaactc gggctgaata tattctccag ctattaagtc cttcccatct
    16381 cgtgaataga gtctcttaat atcagccaga gcaccaacca agcgctcgat gtcttggatg
    16441 cggtcgccga tggaaatata ggccaagata ttgccgatat caccaaactc gatctgaatg
    16501 tcgtattcgt ctcgcaagag gtcataaacc tcgatacctg ttaagcctat tccctgagtg
    16561 taaactgaca acttggttac atcaaaatca cagaccgaca caccatctat taactctttt
    16621 gagtaagcat agtaaccgcc aatggcattg atttcatgac gagcgtactc ggatagctca
    16681 atgacttcct caaacgactc tttaccacga agggccaagt tgcgacgtga aatatccaaa
    16741 ctagccatca ataagtaaga ggcagatgta gactgggtca ggtttataat ctgacgaacg
    16801 tactcgggat tcatctgctc cccgattaaa agaagcgaac tttgtgtcaa actcccacca
    16861 gacttatgca tggaaactgc tgccatatca gctcctgcat ccatagcaga aattggaagt
    16921 ttaccagtga aatgcaaatg cgctccatgg gcttcatcta ctaaaaccat catgccagct
    16981 tcatgagcca tttctgtcaa cccctttagg tctgaacaga tgccgtagta agtaggattg
    17041 ttgattagga tagccttagc atctggatgg tcctttatgg cctgtgctac tcggtcattt
    17101 tcaagaccta aagcgatacc aatcttagga tctacactca tctcgatata gatgggaatg
    17161 gcaccacata gaaccaacgc attgatagca gatttatgga catttcgtgg cagaataatc
    17221 ttatctcctg ccttgcaggt tgccagaatc atagtctgca ccgatgaagt tgttccacca
    17281 atcattagaa aggcatggct agctccaaaa gcatctgcag ccagctcctc tgcatcacga
    17341 ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac atcaatgcct
    17401 acacattttt ctcctaagag ttcgacaagt tctggatttc cccgtccacg cttgtgacct
    17461 ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcctc ataaattggg
    17521 gcttggtttt gatctacctc tttcaaaaca tactcctttc aatattttta ggaccttatg
    17581 aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc tgctctgcaa
    17641 tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg tttcctaact
    17701 ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt gtgctttcac
    17761 cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa aagtaggctt
    17821 ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc tgcctgtccg
    17881 taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt tctaagcttt
    17941 attactatat catgttttta agaacttgta aagtattttt tgataaaaaa caaaaatata
    18001 atagattgaa actagaatag tacacttctg cttctaaaac attattagaa atagatttta
    18061 ctgtcctgat cgatttgttc tgttcttgtt tcattttact atatgttcgt aaatgaaagt
    18121 tctataatga agttagccac ccagccctcc taaaaattag atggttcaac tagctga
//
LOCUS       DAVBOM010000043        18138 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBOM010000043 DAVBOM010000000
VERSION     DAVBOM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.043"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ878_001584"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ878_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3095901.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYTENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VQ878_001585"
     CDS             complement(881..1867)
                     /locus_tag="VQ878_001585"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET3095902.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VQ878_001586"
     CDS             complement(1830..2630)
                     /locus_tag="VQ878_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET3095903.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VQ878_001587"
     CDS             complement(2880..3260)
                     /locus_tag="VQ878_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3095904.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ878_001588"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ878_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET3095905.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ878_001589"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ878_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET3095906.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ878_001590"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ878_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET3095907.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4805..5989)
                     /locus_tag="VQ878_001591"
     CDS             complement(4805..5989)
                     /locus_tag="VQ878_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095908.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5993..6580)
                     /locus_tag="VQ878_001592"
     CDS             complement(5993..6580)
                     /locus_tag="VQ878_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3095909.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6613..6801)
                     /locus_tag="VQ878_001593"
     CDS             complement(6613..6801)
                     /locus_tag="VQ878_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095910.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6980..9220)
                     /locus_tag="VQ878_001594"
     CDS             complement(6980..9220)
                     /locus_tag="VQ878_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET3095911.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9204..9854)
                     /locus_tag="VQ878_001595"
     CDS             complement(9204..9854)
                     /locus_tag="VQ878_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET3095912.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9922..10491)
                     /locus_tag="VQ878_001596"
     CDS             complement(9922..10491)
                     /locus_tag="VQ878_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095913.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFCLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10668..11779
                     /gene="ald"
                     /locus_tag="VQ878_001597"
                     /pseudo
     CDS             10668..11779
                     /gene="ald"
                     /locus_tag="VQ878_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12146..12406)
                     /locus_tag="VQ878_001598"
                     /pseudo
     CDS             complement(12146..12406)
                     /locus_tag="VQ878_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12409..12909)
                     /locus_tag="VQ878_001599"
     CDS             complement(12409..12909)
                     /locus_tag="VQ878_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3095914.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13089..14057)
                     /locus_tag="VQ878_001600"
     CDS             complement(13089..14057)
                     /locus_tag="VQ878_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET3095915.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQDKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14143..14358)
                     /locus_tag="VQ878_001601"
     CDS             complement(14143..14358)
                     /locus_tag="VQ878_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET3095916.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ878_001602"
     CDS             complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ878_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET3095917.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ878_001603"
     CDS             complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ878_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET3095918.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15847..16584)
                     /locus_tag="VQ878_001604"
     CDS             complement(15847..16584)
                     /locus_tag="VQ878_001604"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET3095919.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ878_001605"
     CDS             complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ878_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET3095920.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
BASE COUNT         5187 a         4137 c         3376 g         5438 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agtatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggctgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaagaga
     2461 tgggcatcgt ccggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtagaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcatg attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattgc gaagttttgt atcaaagtca cccttgtcaa
     4201 ttgttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttctatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tgtttgtatt ttggtttggt tttcgaatca
     4741 aaaagagaga atcaagttga ttccctctct atgttagttt ttccttaact tccttataag
     4801 aatgctaaga cctattaaaa acttcctttt tacgtgaact tccccagctt tcgataaata
     4861 gaatccccac tagcaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4921 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4981 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaattgtt tggatgccaa
     5041 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5101 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5161 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5221 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5281 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5341 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5401 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5461 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5521 gtgcttttat gttcaaggga tacagggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5581 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5641 cttgccactg cagatagtag gcttctttcc agcgcccttc ttttagtaaa gttagaattt
     5701 ctgtctttcg cgtcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5761 cctccgagct ggtatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5821 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5881 tatttaaata aaaggtaaca ccgagtacag atgcaaataa aagtaagata atccagttta
     5941 aacgactttt gaaaactttc tttaacaaaa atagactaac atctttcata aactaaacct
     6001 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6061 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6121 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6181 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6241 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6301 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6361 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6421 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6481 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6541 cttgtcgcgt ttttaaggtc acatgagtaa gctgcaacat atctagccct cctttttctc
     6601 actctttaag aattaatagc ctccgctgta atagtttatg acctcataac gaccgtagtt
     6661 ccagcctccg ccaactttat actcagaata gctgtcataa cgagaccatg acggaatcca
     6721 agcatactga tggtcgtgat agttggtact atattcccaa accgtattcc aatcatactt
     6781 gtaactttta gtgactgtca cagcagatac actggactga agaagaccaa tagattataa
     6841 actaactaat taaacgattt ttgctaattt ttaatgattt tatatcctca atattgaata
     6901 cgttttcatt ataccatttt tatcattatt atgcaacaaa tttttagttt atttcactaa
     6961 tctacaacat ttatccttcc tatcgaacac tttcgatttt ccaactatcc acccccttaa
     7021 aacgtatagc tccttgctgg tcagttcgat aaactttgct attgatacct tccagtcgtg
     7081 tcaatgtttc ctgatggggg agtttcattc gattgctctt tccaactgag ataagagtaa
     7141 gctctggttt gagtttttct agaaaggctg gacttgatga ttttttattt ccttgttggc
     7201 tagctttcaa aacatttact ttcaagtctg gatagtgctt cagcaagtcc ttctctcctt
     7261 tctcctccaa atttcccgtg aagagaaatt gcttatccaa gaatttccca tacagaacta
     7321 gggtatcatc gtgtcctcca tctcccattt tccttggaga tagaacttct aactgacttc
     7381 caaaaatggg caagttctcc cctactgtca tactacgcac ctttgtttga gtcgcctgta
     7441 gttctgccac aaattccttc tgtttcagac tgtcttttga tactagaatc tcccctacat
     7501 ggaaagcctt ggtcacctct gacaaatctc caacattctc cttgtccgtg ttagtcaaaa
     7561 ttagctggtc aatcttagct actcctcgac ttttgagata gggaatcaag gttcgctggg
     7621 cattgctggt cgtcatcttt tcttgccatt tttcgatttt cttataagat tctgccttac
     7681 cacctacatc tatgagaatg gttttcccag ttacatcccg taggaaaata ctttctcctt
     7741 gccccacatc cagcatggtg atttcatttt ccagtggata cttggtaagg aaaaagagac
     7801 ctgtaatcaa taaactcaat actgttaatc ctttaatgtt tttcctcaaa tcatagacca
     7861 aagccaagga aattaacaat aagattaaaa gccatgcgtt gggttgacca aagacaagcg
     7921 gtctccttgc cacctgcgag accaagcgaa taatgccctc taaccattca aagataaagt
     7981 tcagctgaat gactggatag agaaaggaaa ggacaaataa gatagacaag agcggtaaga
     8041 agaccaagtc aaaaagaaag gaaaagacaa aggtcaaaag gatagaccaa ggttgaaatt
     8101 ccgcaaaata gaaggataga atgggcaata tgcccaagga gatgactaga ctttcactag
     8161 taacagcctt gagcccctcc ccttctttgc tggtcatggt caggataaaa gcataagcac
     8221 aggacaagac tcctcctgct gtcaagaaaa agtttggcat gacaataaag aggacaagca
     8281 ccgtcaaggc aaaattatcc aagcccttaa ccccatgttg agccagtagc ttttgcaaga
     8341 gactgcgaat aaccgatgct gaaaatccag ttagtcccgc atagataagg gaaaagggat
     8401 aagtcagcca cttcaacttt tcttgtgtca agcccaatcg taaaagtagt ttcttaaatc
     8461 cgtccatgaa aaaccctacc tgcatacctg acaaggcaaa aaggtgaata attcctaaac
     8521 tggaataaag ctcattcatc tcctcaaaat cggtgtccag atgtcctagc aagagtcctg
     8581 tcatgtaatt gcgcataggg tctgggaagt gcatcttaat ccaaaccaca gcctttcgac
     8641 gtaaactgga caggttttca cctatatccc aactgccaac cttttggaat gactggattc
     8701 ttttaatatt gagtgtctgg taaattccct gagtcttcag atagccttgg tagtcaaagc
     8761 caccaaaatt tctctgccct tctggctccg aaagcttccc ttctagtcct atctcatgaa
     8821 ggtcagttaa agcttgaaag gcttctttct cctcctcgga ctggagttta taatagactt
     8881 ggaaagcacg accatcagac ttaccacgaa aggacagact gtcaccgtta accttaatag
     8941 tgtctggtaa aatccgtacc ctttcaacag aatccaccaa attttgactc acttgactct
     9001 gttgccaagt ttgaaacaga aaccagaagc caaagactcc acaaatcact agaactttac
     9061 ctgctgattt ccaaggaaat tggataaaga ggcagactag cagaaaaaca aaacccaaca
     9121 aagcaaaata ggatactgag aaaatggcgt agtaaagcca tagtaacaga aaactcaggt
     9181 aaattagggg aatagagaaa ttcttaatcc actgtaacat agtctttaag tttttctatg
     9241 gtcttggcac caatgccaga gaccttcttg agctcgtcta ctgacttgaa cttgccattt
     9301 gcctcacgat ggtcaataat gtcctgagct cgttttcctc ccagtccctt gacctgcttg
     9361 agttcttcca gactggcctt gttgagattg accttctttt ccttgcttgt tgaagaagct
     9421 gtccccgaac cagtctgttg actaactgct tcttctccct tagtaggaac gtaaaccaga
     9481 gcctcatcac taactttctg agctagattg agcgacttgc tgtctgcttg ctctgtcaag
     9541 ccaccagcct tctgaacagc atcattgact cgactaccta caggcaagtc ataaatccct
     9601 ggcgatttga cagcaccttt gacatctact gtgattagat cttgttcaac tggttcttcc
     9661 ttctcttcct tgttcacttc ctttccggtc gatgagtcct tggaaacagc tgcaacttca
     9721 gcctgcaaat tcgtctcttt gacagatgtt tgtggagctg gctttagcag gaaaaatccg
     9781 cctacaagca agcccagacc agtacagatg acgatgattt tatactcttt gattttctcg
     9841 ataattgctt ccatattttc tcctctctta gattattcgt aagaggaaga aaaaacagtc
     9901 gaaaaatttc ttttcaactg cttatttatt tgcaaaatag tcttccttgg tcaagacata
     9961 atgaactctt gtcacgattc ggcctttttc atgctggtcc atacaagcat atggttctgc
    10021 atgggaaaaa cgcatgcctg atttctccat gacctttcct gacgcgggat tagccttatc
    10081 gtgaagggca gtcaacttat tcatccctat cttctcaaaa gctagctcaa tcacagcacg
    10141 attggcttct gtcgttaatc cttgattcca atacttttta ttgataatgt agccaatagc
    10201 tgccttctta agaacaggat caatcttgtg taagtcaata gttccgataa acttgccgtt
    10261 atcttttaat tcaatccccc aacgtcccaa gggattagcc aagcagaact gagcaatgtt
    10321 attcttggtt tcttccaagc tttgattggt tggaaaagtg taacgtgtat tacccttgtc
    10381 cgaggcatag tcaaacattg cttccgcatc atccaaagtt acaggtctaa gcaataaacg
    10441 ctccgtttct atagacggat actgggcaaa tttcacaaat attgattcca tacttttccc
    10501 tccattagag cttgattttc actagtctag cataaaaaaa tttggatgac aagtttttct
    10561 tgatttttga agcggtttca tatacaatga aaccgtcaca tttttgattt atgaactgga
    10621 atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt tatctcaatg ttaatcggaa
    10681 tcccaaaaga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
    10741 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
    10801 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
    10861 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
    10921 gcgacgatct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
    10981 ctatgttagc agcaaaaaca acaggaattg cctatgaaac tgttcgtgac aatcaaggac
    11041 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt caaatcggag
    11101 ctcacttcct tactaagcaa gctggtggct ctggtgttct acttggtggt gtaccaggtg
    11161 ttccaaaagg aaaagtaact atcatcggtg atggtgtcgt cggtacacat gctgcccgca
    11221 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
    11281 ttctagaaga agtctttgga agtcaaattc aaactattat atctaattca ttcaacattg
    11341 aagcaagtgt gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
    11401 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
    11461 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
    11521 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
    11581 tgcccgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
    11641 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
    11701 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
    11761 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
    11821 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
    11881 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
    11941 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
    12001 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
    12061 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
    12121 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
    12181 aaatcatttc tttggcacct ttgtatggaa actcaaaaga agattggtca atcttatcta
    12241 agactgcttg cacgggttta actaaaaagc gatcgtcata aatgccgcca ataatcttgc
    12301 cgcggaagta aagaatatac tccccaatca tggaacggta agtcacatca tctaatcctg
    12361 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
    12421 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
    12481 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
    12541 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
    12601 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
    12661 aggatatgca tagacaaaat ccataacagc cacaaggtca gatccattcc aaaatccaac
    12721 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
    12781 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
    12841 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
    12901 gtcaatcatc ttttcaaatt cctactttct tgcgccctgt gattatgaca caggaagatg
    12961 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
    13021 ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc aggcgaactt
    13081 cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat aatctgagcg
    13141 acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat ctgatggatg
    13201 ttcttgagtt tatcttgagc atcaatcaaa ccggacttga cattacgtgg caggtcaatc
    13261 tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt caagaacatc
    13321 ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc atcatccaag
    13381 gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc catgagacga
    13441 gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg aaggtaagga
    13501 tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc ttccaccgct
    13561 ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac tgccaaggtc
    13621 actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac atcatgctgt
    13681 ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg cttcccagta
    13741 ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc atcatttttg
    13801 accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg atttaccaag
    13861 gccatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc tcccaaaacc
    13921 tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat caaacgaaga
    13981 tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag ttgaatgtct
    14041 attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt tattatagca
    14101 gagggatgga gaaattacta gcccaaaccc aatgaataaa tgctagtgtt ctagatattc
    14161 ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa ctggcatgct cctccaaaaa
    14221 gcgactgacc tcatcaaaat catctgtatg ttttggaaaa gctgcctctt caaaagcgag
    14281 gtctgccaaa attgctttgg gattgttact tttaggattg cgctcggtca tgagccaagt
    14341 gtaaaatgat tttctcataa gcctccctaa atcaactctg taccaaactg gtcctgcttg
    14401 attttaccag ccttcataag accacctaaa gctttcttga actgaccttt agaaatgcca
    14461 aaggttgcct tgatgtcgtc tggagatgac ttgtcattta aggtcatgaa accgccattg
    14521 ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa ggagcgtggt
    14581 ttgagggaga ggttcaaagt gcggtccact tcacggaaac caataacgcg cgcatctaat
    14641 acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc aagcatgtta
    14701 ttttctggta ggtaaacaaa agttcctgat agcttgagac ggtaaacaat ggctggccag
    14761 ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc ttcttgataa
    14821 gccaagagac cccagatacg gtctttctta tccacttcaa gacggatgta gagttggtcg
    14881 cccttcttag gccagagttc cttgagctca gggagaatat cgagtgacac aacgatttcc
    14941 ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc tgtgacacgt
    15001 ccccaaccaa attggtcctg agtggcagtc acttctaagc ttgtcaggcg gagtttttgc
    15061 ttcatatccg tgtatgcaaa acctttgacc gtatccccta ctgtatgttg gccttcttcc
    15121 ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc gttttcatcg
    15181 atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc tttcgaataa
    15241 aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc aaaagttctt
    15301 tctctttgtt ggcagtcata tcgtcgatgt gtttaacagc atcgtctgtt actttttgaa
    15361 tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt tcttgtttct
    15421 tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca ttttcgccga
    15481 ccttcttcac ttctttagca aggtcacgac gagtctcttc tgtaagagct gggacaacca
    15541 agcgaatcac agaaccgtca ttagctggtg tgataccaag atcagaagcg ttcaaggcac
    15601 gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca cgcgcttctg
    15661 gaatcgtaat tgaagcgatt tggttaagag gagtttcaac tccatagtat tctacatgta
    15721 tacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat tcacgagcaa
    15781 gtgattggtg agactgggtc attctctctt tagctttttc aataattgcg ttagccatat
    15841 tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat tttcaccaaa
    15901 tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt caatgtcgtt
    15961 gtccattgag agggttgaag ctgttgagtc catgatacga agacctttat tgataacgtc
    16021 acggtgggtc aattcttcaa acttaacagc tgtcttatct ttcttaggat cggcattgta
    16081 aacaccatcg acaccatttt tagccatgag gatggcatcc gcttcgattt cagctgcacg
    16141 aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac caaagataac
    16201 gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct ctgccacttg
    16261 ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca atgaatctgc
    16321 catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct gaacacggtc
    16381 catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa taacaagggc
    16441 aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt gaactgtttg
    16501 gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact tgattaaaat
    16561 acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc tattttatca
    16621 caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta gacagtcaaa
    16681 aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc cttcttatca
    16741 cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat tggttggaaa
    16801 tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt cgtctcgggg
    16861 aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc aactaagccc
    16921 gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa gaagagattt
    16981 ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat gtaagaattg
    17041 cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat catttggaag
    17101 acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt gtataggcta
    17161 ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa ttctccatca
    17221 cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg gccataaagc
    17281 atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc aaagtacttt
    17341 tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc atggaaatcc
    17401 ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt atcataacga
    17461 gatttgagat agaccttact catatcgata gtgttgacat cgataatagg cgctgctgca
    17521 tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc cagggcatcg
    17581 ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc tgtaatttca
    17641 tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat ttgagagaaa
    17701 ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc agcagattcc
    17761 aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc atttgtcaaa
    17821 gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt tttatgctgg
    17881 ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg ctctgcgatt
    17941 tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata agattgagac
    18001 acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa agccaatcag
    18061 acttacaagc tttcgagttt cttggctcag gctgaaaaag tccattggac ttacttcgct
    18121 ctcgaatttc ttggctca
//
LOCUS       DAVBOM010000044        18101 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBOM010000044 DAVBOM010000000
VERSION     DAVBOM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.044"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            3..308
                     /locus_tag="VQ878_001606"
     CDS             3..308
                     /locus_tag="VQ878_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3095921.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            356..1831
                     /locus_tag="VQ878_001607"
     CDS             356..1831
                     /locus_tag="VQ878_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET3095922.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2091..8792
                     /locus_tag="VQ878_001608"
     CDS             2091..8792
                     /locus_tag="VQ878_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET3095923.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQAFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9040..9896)
                     /locus_tag="VQ878_001609"
                     /pseudo
     CDS             complement(9040..9896)
                     /locus_tag="VQ878_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10107..10466)
                     /locus_tag="VQ878_001610"
     CDS             complement(10107..10466)
                     /locus_tag="VQ878_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET3095924.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10558..11514
                     /locus_tag="VQ878_001611"
                     /pseudo
     CDS             10558..11514
                     /locus_tag="VQ878_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11498..12055
                     /locus_tag="VQ878_001612"
     CDS             11498..12055
                     /locus_tag="VQ878_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3095925.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12048..12302
                     /locus_tag="VQ878_001613"
     CDS             12048..12302
                     /locus_tag="VQ878_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095926.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12314..14368
                     /locus_tag="VQ878_001614"
     CDS             12314..14368
                     /locus_tag="VQ878_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET3095927.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEKSKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14547..15407
                     /locus_tag="VQ878_001615"
     CDS             14547..15407
                     /locus_tag="VQ878_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET3095928.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ878_001616"
     CDS             15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ878_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3095929.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16356..16922
                     /locus_tag="VQ878_001617"
     CDS             16356..16922
                     /locus_tag="VQ878_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET3095930.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16933..18045
                     /gene="msrB"
                     /locus_tag="VQ878_001618"
     CDS             16933..18045
                     /gene="msrB"
                     /locus_tag="VQ878_001618"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3095931.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5444 a         3449 c         3979 g         5229 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattccgta
      241 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacacggat
      301 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      361 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      421 catcatgttg atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      481 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
      541 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt
      601 gagtattaca gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
      661 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
      721 cgatacactt gatgtcgata tatttgatat ctggcacttg tctatcacag gtctcttgat
      781 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
      841 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
      901 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
      961 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1021 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1081 cttcatcggt ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc
     1141 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1201 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1261 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt
     1321 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1381 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1441 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1501 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     1561 aggtaccctt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     1621 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     1681 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     1741 agccttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     1801 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     1861 aaatcaaaga gcaaactagg aaactagcca caggttgctc aaaacacagt tttgaggttg
     1921 tagatgaaac tgacgaagtc agtaatcata tctacggcaa ggcgacgctg acgaagtttg
     1981 aattggattt tcgcagagtg taaattgttg aaactaggtt gtcataccat gtataccact
     2041 tgggctttgg tagtagctaa ctgcactaaa tataatataa ggagggtttt atggggaaag
     2101 gccattggaa tcggaaaaga gtttatagca ttcgtaagtt tgctgtggga gcttgctcag
     2161 taatgattgg gacttgtgca gttctattag gaggaaatat agctggagaa tctgtagttt
     2221 atgcggatga aacacttatt actcatactg ctgagaaacc taaagaggaa aaaatgatag
     2281 tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt agttgaaagg acagaacaaa
     2341 gtgaacctag ttcaactgag gctattgcat ctgagaagaa agaagatgaa gccgtaactc
     2401 caaaagagga aaaagtgtct gctaaactgg aagaaaaagc tccaaggata gaatcacaag
     2461 cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc tgtaacaaat gaagaaatga
     2521 atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa ttggtacttt aaactcaatg
     2581 caaattctaa ggaagccatt aaacctgatg tagacgtatc tacgtggaaa aaattagatt
     2641 taccgtatga ctggagtatc tttaacgatt tcgatcatga atctcctgca caaaatgaag
     2701 gtggacagct caacggtggg gaagcttggt atcgcaagac tttcaaacta gatgaaaaag
     2761 acctcaagaa aaatgttcgc cttacttttg atggcgtcta catggattct caagtttatg
     2821 tcaatggtca gttagtgggg cattatccaa atggttataa ccagttctca tatgatatca
     2881 ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc tgtccatgca gtcaacaaac
     2941 agccaagtag ccgttggtat tcaggaagtg gtatctatcg tgatgtgact ttacaagtga
     3001 cagataaggt gcatgttgag aaaaatggga caactatttt aacaccaaaa cttgaagaac
     3061 aacaacatgg caaggttgaa actcatgtga ccagcaaaat cgccaatacg gacgacaaag
     3121 accatgaact tgtagccgaa tatcaaatcg ttgaacgagg tggtcatgct gtaacaggct
     3181 tagttcgtac agcgagtcgt accttaaaag cacatgaatc aacaagccta gatgcgattt
     3241 tagaagttga aagaccaaaa ctctggaccg ttttaaatga caaacctgcc ttgtacgaat
     3301 tgattacgcg tgtttaccgt gacggtcaat tggttgatgc taagaaggat ttgtttggtt
     3361 accgttacta tcactggact ccaaatgaag gtttctcttt gaatggtgaa cgtattaaat
     3421 tccatggagt atccttgcac cacgaccatg gggcgcttgg agcagaagaa aactataaag
     3481 cagaatatcg ccgtctcaaa caaatgaagg agatgggagt taactccatc cgtacaaccc
     3541 acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga actaggttta ctcgttcagg
     3601 aagaggcttt tgatacttgg tatggtggca agaaacctta tgactatgga cgtttctttg
     3661 aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa atggtctgat tttgacctac
     3721 gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt catgtggtca attggtaatg
     3781 aaataggtga agctaatggt gatgcccact ctttagtaac tgttaaacgt ttggtcaagg
     3841 ttatcaagga tgttgataag actcgctatg ttaccatggg agcagataaa ttccgtttcg
     3901 gtaatggtag cggagggcat gagaaaattg ctgatgaact cgatgctgtt ggatttaact
     3961 attctgaaga taattacaaa gcccttagag ctaagcatcc aaaatggttg atttatggat
     4021 cagaaacatc ttcagctacc cgtacacgtg gaagttacta tcgccctgaa cgtgaattga
     4081 aacatagcaa tggacctgag cgtaattatg aacagtctga ctatgggaat gatcgtgtgg
     4141 gttgggggaa aacagcaacc gcttcatgga cttttgaccg tgacaacgct ggctatgctg
     4201 gacagtttat ctggacaggt acggactata ttggtgaacc tacaccatgg cacaaccaaa
     4261 atcaaactcc tgttaagagc tcttactttg gtatcgtaga tacagccggc attccaaaac
     4321 atgacttcta tctctaccaa agccaatggg tttctgttaa gaagaaaccg atggtacacc
     4381 ttcttcctca ctggaactgg gaaaacaaag aattagcatc caaagtagct gactcagaag
     4441 gtaagattcc agttcgtgct tattcgaatg cttctagtgt agaattgttc ttgaatggaa
     4501 aatctcttgg tcttaagact ttcaataaaa aacaaaccag cgatgggcgg acttaccaag
     4561 aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt tgcctatcaa ccaggtacct
     4621 tggaagcaat tgctcgtgat gaatctggca aggaaattgc tcgagataag attacgactg
     4681 ctggtaagcc agcggcagtt cgtcttatta aggaagacca tgcgattgca gcagatggaa
     4741 aagacttgac ttacatctac tatgaaattg ttgacagcca ggggaatgtg gttccaactg
     4801 ctaataatct ggttcgcttc caattgcatg gtcaaggtca actggtcggt gtagataacg
     4861 gagaacaagc cagccgtgaa cgctataagg cgcaagcaga tggttcttgg attcgtaaag
     4921 catttaatgg taaaggtgtt gccattgtca aatcaactga acaagcaggg aaattcaccc
     4981 ttactgccca ctctgatctc ttgaaatcga accaagtcac tgtctttact ggtaagaaag
     5041 aaggacaaga gaagactgtt ttggtgacag aagtgccaaa agtacagacc attattggag
     5101 aggcacctga aatgcctacc actgttccgt ttgtatacag tgatggtagc cgtgcagaac
     5161 gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg tattgtaacg gtgaaaggta
     5221 tggctgacgg acgagaagta gaagctcgtg tagaagtgat tgctcttaaa tcagagctac
     5281 cagttgtgaa acgtattgct ccaaatactg acttgaattc tgtagacaaa tctgtttcct
     5341 atgttttgac tgatggaagt gtacaagagt atgaagtgga caagtgggag attgccgaag
     5401 aagataaagc taagttagca attccaggtt ctcgtattca agcgaccggt tatttagaag
     5461 gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa tcctgcggca cctgcagtac
     5521 caactgtaac ggttggtggt gaagctgtca caggtcttac tagtcaaaaa ccaatgcaat
     5581 accgcactct tgcttatgga gctaagttgc cagaagtcac agcaagtgct aaaaatgcag
     5641 ctgttacagt tcttcaagca agcgcagcaa acggcatgcg tgcgagcatc tttattcagc
     5701 ctaaagatgg tggccctctt caaacctatg caattcaatt ccttgaagaa gcgccaaaaa
     5761 ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct caaagaagac caaactgtca
     5821 aattgtcggt tcgagctcac tatcaagatg gaacgcaagc tgtattacca gctgataaag
     5881 taaccttctc tacaagtggt gaaggggaag tcgcaattcg taaaggaatg cttgagttac
     5941 ataagccagg agcagtcact ctcaaagcgg aatatgaggg agctaaaggc caagttgatc
     6001 tcactatcca ggccaatact gagaagaaga ttgcgcaatc tatccgtcca gtaaatgtag
     6061 tgacagattt acaccaagaa cctactcttc cgtcaacagt aacggttgag tatgacaaag
     6121 gtttccctaa agctcacaaa gtcacttggc aagctattcc gaaagaaaaa ctagactcct
     6181 atcaagcctt tgaagtacta ggtaaagttg aaggaattga ccttgaagcg cgtgcaagag
     6241 tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt gacaactcca atcgcagaag
     6301 caccacaatt accagaaagc gttcggacat atgattcaaa tggtcacgtt tcatcagcta
     6361 aggttgcatg ggatgcgatt cgtatagagc aatacgctaa ggaaggtgtc tttacagtta
     6421 atggtcgctt agaaggtact caattaacaa ctaaacttca tgttcgcgta tctgctcaaa
     6481 ctgagcaagg tgcaaatatt tctgaccaat ggaccggttc agaattgcca cttgcctttg
     6541 cttcagactc aaatccaagc gacccagttt caaatgttaa tgacaagctc atttcctaca
     6601 ataaccaacc agccaatcgt tggacaaact ggaatcgtag taatccagaa gcttcagtcg
     6661 gtgttctgtt tggagattca ggtatcttga gcaaacgctc cgttgataat ctaagtgtcg
     6721 gattccacga agaccatgga gttggtgcac cgaagtctta tgtgattgag tattatgttg
     6781 gtaagactgt cccaacagct cctaaaaacc ctagttttgt tggtaatgag gaccatgtct
     6841 ttaatgattc tgccaactgg aaaccagtta ctaatctaaa agcccctgct caactcaagg
     6901 ctggagaaat gaaccacttt agctttgata aagttgaaac ctatgctgtt cgtattcgca
     6961 tggttaaagc agataacaag cgtggaacgt ctatcacaga ggtacaaatc tttgcgaaac
     7021 aagttgcggc agccaaacaa ggacaaacaa gaatccaagt tgacggcaaa gacttagcaa
     7081 acttcaaccc tgatttgaca gactactacc ttgagtctgt agatggaaaa gttacggcgg
     7141 tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt tccaagcgtt cgtgaaggtg
     7201 agccagttcg tgtcatcgcg aaagctgaaa atggcgacat cttaggagaa taccgtctgc
     7261 acttcactaa ggataagagc ttactttctc ataaaccagt tgctgcggtt aaacaagctc
     7321 gcttgctaca agtaggtcaa gcacttgaat tgccgactaa ggttccagtt tacttcacag
     7381 gtaaagacgg ctacgaaaca aaagacctga cagttgaatg ggaagaagtt ccagcggaaa
     7441 atctgacaaa agcaggtcaa tttactgttc gaggccgtgt ccttggtagt aaccttgttg
     7501 ctgagatcac tgtacgagtg acagacaaac ttggtgagac tctttcagat aaccctaact
     7561 atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa tgatattgac aaaaactctc
     7621 atgaccgcgt tgactatctc aatgacggag atcattcaga aaatcgtcgt tggacaaact
     7681 ggtcaccaac accatcttct aatccagaag tatcagcggg tgtgattttc cgtgaaaatg
     7741 gtaagattgt agaacggact gttgcacaag gaaaagttca gttctttgca gatagtggta
     7801 cggatgcacc atctaaactc gttttagaac gctatgtcgg tccagagttt gaagtgccaa
     7861 cctactattc aaactaccaa gcctacgacg cagaccatcc attcaacaat ccagaaaatt
     7921 gggaagctgt tccttatcgt gcggataaag acattgcagc tggtgatgaa atcaacgtaa
     7981 catttaaaga tatcaaagcc aaagctatga gatggcgtat ggagcgtaaa gcagataaga
     8041 gcggtgttgc gatgattgag atgaccttcc ttgcaccaag tgaattgcct caagaaagca
     8101 ctcaatcaaa gattcttgta gatggaaaag aacttgctga tttcgctgaa aatcgtcaag
     8161 actatcaaat tacctataaa ggtcaacggc caaaagtctc agttgaagaa aacaatcaag
     8221 tagcttcaac tgtggtagat agtggagaag atagccttcc agtacttgtt cgcctcgttt
     8281 cagaaagtgg aaaacaagtc aaggaatacc gtatccactt gactaaggaa aaaccagttt
     8341 ctgagaagac agttgctgct gtacaagaag atcttccaaa actcgaattt gttgaaaaag
     8401 atttggccta caagacagtt gagaaaaaag attcaacact gtatctaggt gaaactcgtg
     8461 tagaacaaga aggaaaaact ggtaaagaac gtatctttac agcgattaat cctgatggaa
     8521 gtaaggaaga aaaactccgt gaagtggtag aagctccgac agaccgcatc gtcttggttg
     8581 gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt gtcagaaaaa gcagatacaa
     8641 aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc ccagttacca aatacaggta
     8701 gtgcgtcaag ccaagcagca gtagcagcag gtttagctct tctaggtttg agtgcaggat
     8761 tagtagttac taaaggtaaa aaagaagact agaaattttg ataccttctt tatcattaaa
     8821 gaccaaagaa aaactcttgt cctaaataga agataaagag tctggaacaa aatagttctc
     8881 aaccacaaaa aagctagata tttccaattg cggaactcta gctttttaat tttgagtcgt
     8941 tctctgattg tatagtagat tgaaactaga gtagtacact tctacttcta aaacattgtt
     9001 agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttgattt cactatgttt
     9061 taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac gcttgcctct
     9121 cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag gttccacatc
     9181 aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat aaaagcgcct gacattcttt
     9241 agctttcaag ttttgatagc gttcgttcat atacagtccc ttttgagggg ctgattcagg
     9301 ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt tctggtactt
     9361 gatatggtga aaacgatagc accagccatc aggatgtatg tagctatcct ccttgtcatt
     9421 atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt gtttcttatc
     9481 aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga cttgtatctg
     9541 ttcttgaagt ttggcggaga atttctctgt ctttttcttc cacacaaaac tatacttgtt
     9601 ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca ctaactcttc
     9661 catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag aagagtagat
     9721 acaagcattt taaggtgata agacgggcga tcaaaggcat gatagaaggc gtggaaatga
     9781 caatcctcca aggtattcac cactttttca atagtaaaaa cgagatggtc ttgtggcaag
     9841 aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat atgcatggga
     9901 tagcctttct aaatggttta ttgtgcaatt ctattttacc aagactatcg caaccatgca
     9961 aaaaagcaac ggcaaatccg ttgctttttt tggagataag agactattgt cccagactct
    10021 tttctttgta taaaattgta tagtgttatt gtctatacta ttttgtagag aaagcaaaaa
    10081 tccctagaaa atgcttaggg attcgactat ttcattaaga acaattcaac aatcatttct
    10141 acatacatga taagggttaa taagaatcct gcacgccaga agaatttgat gaatttagga
    10201 tagtaaaagc tgcgtttttt caaaaggaag aaaaagacga gaataatggc taggatcgag
    10261 agggttagcc ccagtctagg gaggaaatta tgggtaaagg ttttagctgt aatcaagtaa
    10321 tactcaaata ccaagactgg aaaagccaaa tccgcaaagt ttcgtcctag tttttttaat
    10381 ctaaaaagtt tggttaggat aatgcagatg actaaggtca gtatcaataa taaaatagat
    10441 gctaatttca ttaaaatcat acccatattg tatcataaaa aaaggctaat ggaaacgaga
    10501 aacagaggaa tttataagaa agtcaggctt ttgagattgt gggtgatttt tgttataatg
    10561 aaagttataa aatcttataa taccttgaat gattattatc gaaaactctt tggagaaaag
    10621 acttttaaag tccctattga tgcgggattt gactgtccca atcgtgatgg aactgtggct
    10681 catggaggct gtactttttg tacggtttca ggttctggag atgctattgt agccccagat
    10741 gcgcctatcc gtgagtaatt ttataaggaa attgacttta tgcaccgtaa gtggccggat
    10801 gttcagaagt atctggttta ttttcaaaat tttaccaaca ctcatgaaaa ggtggaagtt
    10861 attcgagagc gttatgaaca ggctatcaat gagccaggtg tggtaggaat caatattgga
    10921 acgcgcccag actgtttacc agacgaaacc atcgaatatt tggctgagtt atcggagtgc
    10981 atgcatgtga cgtttgaatt gggcttgcaa actacttatg aagcaacctc tgacctgatt
    11041 aaccgtgcgc attcttatga attgtaggtg gaaacggtca agcgtttgag aaagtatcca
    11101 aaaattgaga ttgtttccca tttgatcaat ggtttgcctg gtgaaaccca tgagatgatg
    11161 gttgaaaatg tccgccgttg tgtcacggat aacgatattc aagggattaa actgcatttg
    11221 ctccatctta tgacaaatac tcgtatgcaa cgagattacc atgaggggcg tttacaattg
    11281 atgagtcagg acgaatatgt cagggtcatc tgtgaccaac tggaaattat tcccaaacat
    11341 atcgtcatcc atcgaattac aggagatgcg cctagggata tgctgcttgg gcctatgtgg
    11401 agcctcaata aatgggaagc tctcaacagc attgagatgg agatgcgacg tcgtggaagt
    11461 gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg aaaagaccac ttgagatggc
    11521 acatgatttt ttggctgagg tcgtgacaaa agaggatgtc gtagtggatg cgactatggg
    11581 aaatggtcat gacacgcttt ttttagccaa gctagccaag caagtctatg cctttgatat
    11641 tcagaagcaa gccttggaaa agacccaaga gcgtttgcat caggctgact tgacaaatgc
    11701 ccagttaatc ttgcaaggcc atgagacact ggaccagttt gtgataaaag ctaaggcagg
    11761 gatttttaat ctgggctatt tgccgtcagc tgataagtct gtcatcaccc gaccgcagac
    11821 aacgattgag gcattagaaa agctatgtgg cttacttgtc aaaggtggac gaattgctat
    11881 tatgatttac tatggtcatg aaggaggcga tctcgagaga gatgctgtct tggattttgt
    11941 gatccagttg aaccaacaag agtacacagc tgccatttac cgaactttaa accaagtcaa
    12001 caacccgccg tttttagtga tgattgaaaa attagagaga tacagacatg gataaacaat
    12061 acttacacga aaagctggat gccatgcgcc agaattttgt tgaatcaacc caccacgaac
    12121 gagcggtggg cgtgctagac caagcgcata tgagcaaaaa aatgcttaaa atcaagaaaa
    12181 aattagttgc tcttgaaatg gaacggtgcc agagaaaaat tgagcacaaa gactgttcca
    12241 agattgacca aaaaatcaaa gagcagaagg agatatttga atcctgttgt aaaaaagatt
    12301 aaggaggacg tgcgtggaat tactgattta cctcatccta tttttactgg ttttgattgt
    12361 ctcaagtaca accaataagc tcctgccctt tttgcctctc cctttggtgc aaattctttt
    12421 gggaattgtg attggtctct ttttacccaa tactgacttt caccttaata cggagttgtt
    12481 tttggcactg gttatcggac ccttgctttt ccgagaggct gaagaagcag atgttacggc
    12541 tattttaaaa cactggcgaa tcattgttta tctcatattt ccagtgattt ttatctcgac
    12601 cctgagtttg ggtggcttgg cccatcttct ttggttcagc cttcccttgg cagcttgctt
    12661 ggctgttggg gcagcccttg gtcctacgga cttggtggcc tttgcctctc tttcggagcg
    12721 ttttagcttt cctaagcgcg tgtccaatat tcttaagggc gaaggactct tgaatgatgc
    12781 ttctggtttg gtggcttttc aggtagcttt gacagcttgg acaactggag ctttttctct
    12841 ggggcaagct agcagttcgc tcatcttttc aatcctaggc ggttttttaa ttggattttt
    12901 aacagccatg accaaccgct tcctccatac cttcttgcta agtgtgcgcg caacggatat
    12961 tgccagtgaa cttttattag aattgagttt gcctctagtg accttctttc tggcagaaga
    13021 agtccatgtt tcaggtatta ttgccgtcgt agttgctgga attttaaagg caagtcgctt
    13081 caagaaaatc acgctcctcg aagcccaagt ggatacggtg accgagacgg tctggcatac
    13141 agtgaccttt atgctcaacg gttctgtctt tgtgatttta gggatggagt tggaaatgat
    13201 agcagaacct atcttgacca atccaatcta taatcctcta cttttattgc tatctctcat
    13261 cgcccttacc tttgtcctct ttgtcattcg ttttattatg atctatggct attatgccta
    13321 tagaacccga cgcctcaaga aaaagctaaa taagtatatg aaggacatgt ttctcttgac
    13381 cttttcaggt gttaagggaa cggtgtcgat tgctacgatt ctcttgatac caagtaatct
    13441 agaacaggag tatcctcttt tgcttttcct tgttgcaggt gtgacgcttg tcagcttttt
    13501 aacaggtctc ttggtcttgc ctcatctttc tgatgaagag gaaaaaagca aggattatct
    13561 catgcatatc gccattttga atgaagtaac gctagagttg gaaaaagagt tggaagacac
    13621 cagaaataaa cttcccctct atgcggctat tgacaattat catggacgta ttgaaaatct
    13681 cattttaagc caagaaaacc aggatgatca agaagactgg gctgctttga aactcttgat
    13741 tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa gaggggaaca ttagcaatcg
    13801 tgcttaccga gtttaccaac gttatctgaa aaatatagaa caaggaatca atcgtaaact
    13861 tgcctcaaga ctgacctatt atttccttgt ttccttgagg attttacgtt ttctccttca
    13921 tgaagttttt actcttggaa agaccttccg tagctggaag gacaaggagc aaagccgtct
    13981 ccgtgctctt gattatgacc aaattgcaga gctctatctt gccaatacgg agatgattat
    14041 tgaaagtttg gaaaacctga agggagtcta cagacgctct ttgattagtt ttatgcagga
    14101 gtctcgtctt cgagaaacag ctattatcag cagtggtgcc tttgtcgaac gggttatcaa
    14161 tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc tattatctgg agcgcaagtt
    14221 gattttcgaa tacgaagaaa aacgattaat tacaactaag tatgccaaga aattacgaca
    14281 aaatgtaaat aacttagaga actattcctt gaaggaagct gccaataccc tgccgtatga
    14341 tatggtggaa ttggtaagaa gaaattagtt aatactcttc gaaaatctct tcaaaccacg
    14401 tcagcgtcgc cttggattat atatgtgact gacttcgtca gtttcatcta caacctcaaa
    14461 gcagggcttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    14521 taagattata aatgaaggag tatgacatga aaaagtggtg gaaagagctg atagacaagc
    14581 ctttattaaa agcttttttg cattattatc aagcatcaga tagtgagttg accagtgtcg
    14641 cagtagccta ctattggttg atttcgattt tccccctgct tttggtggtg gtcaatatcc
    14701 tcccctattt tcagattcct gtgggagaat ttctgtgctt tatgaaagac gttctgcccc
    14761 caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt tttgacgcaa ccttcaacag
    14821 gtttattaag tttttctgtt ttatcggcgt tatggagttt ttcaaaatct atgaatttct
    14881 tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag tcgtggactt atttcccatc
    14941 agatgctaag tctcctagtc agttttggct tgcagctcct ctttgcgttt gccttgtttt
    15001 tgatcttatt tggtcagatg attttggctt tacttgctca ttattggaca aaagatggca
    15061 ttatctatca ggctttacaa gggttggcag gtcctctgat ttacgccctc ctctttgcta
    15121 tcttggtcat gctttattat tttcttccca atatatctaa caggaaaatt agctataccc
    15181 taccaggcag tgcctttgtt ctcttagtga ttttaggttt actaactctg ttctctagtt
    15241 atctcaatta ctatgtccat catttggtgg atgtccgaat tttaggttcc gttcttcttg
    15301 ttgttatgat gttttggttt atcttgattg ctaaaattgt tatcctaggc gcggttatca
    15361 atgccagtat gcagagtttg aaagatccgg tctttaaaaa agactaacta tttatccatt
    15421 ataaaagcgc atagtatcaa gactttatag aaccttgata ctatgcgctt ttgcgctttt
    15481 gtgctttgac agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt
    15541 cctattttcc cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta
    15601 tcaataaaat gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt
    15661 ggcagggatt ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg
    15721 agtgttacta gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt
    15781 tactagttta ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt
    15841 gggctatgga gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac
    15901 tggggcaatt attatccttc ttggtttgca ccaaatggag attctacact ttaaggggct
    15961 ttataaggaa aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca
    16021 ggcattttta ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct
    16081 ggggtctgtt ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct
    16141 catgttggtg tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag
    16201 ttatgttttg aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg
    16261 tggttttctc attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag
    16321 tcaattattt gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc
    16381 ttggagcagg ttcgctcctt tggttgacgg cttgttcagg caagtccgtg actagtgaac
    16441 accaaacgaa agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag
    16501 ggaaagaggt ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg
    16561 attacaaggg caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg
    16621 ctagtcttcc agatacggat gagattgcta aagaagctgg tgatgactat gtggtcttga
    16681 cagtagtgtc accaggacat aagggagagc aatctgaagc ggactttaag aattggtata
    16741 agggattgga ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa
    16801 cttatggtgt ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca
    16861 aaacacatcc aggcttcatg gaaaaagatg caattttgca aactttgaag gaattagcct
    16921 aggaggtgtc ttatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta
    16981 gccataaccg gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa
    17041 attgaaaagg cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa
    17101 gacgcagact tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat
    17161 ttctcacgcg ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa
    17221 acaaccaagt acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat
    17281 gatgccaagc aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca
    17341 accagcaaaa ataaacaagg aaatgatgtg gggacccagt accgtactgg tgtttattac
    17401 acagatgaca aggatttgga agtgattaac caagtctttg atgaggtggc taagaaatac
    17461 gatcaacctc tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac
    17521 catcaagact atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg
    17581 gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag
    17641 accctgtcac ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca
    17701 aaccgttact gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct
    17761 ctcttttcat caaaagacaa atttgagtct ggttgtggct ggcctagttt tacccaaccc
    17821 atcagtccag atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa
    17881 gtgcggagcc gagtaggaga ttctcacctt gggcatgtct ttacggatgg tccacaggac
    17941 aagggcggct tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa
    18001 atggaagaaa aaggctacgc ttatttacta gattatgttg attaatactc ttcgaaaatc
    18061 tcttcaaacc acgtcagcgt cgccttaccg tatgtagggt t
//
LOCUS       DAVBOM010000045        17888 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBOM010000045 DAVBOM010000000
VERSION     DAVBOM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.045"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            1..773
                     /locus_tag="VQ878_001619"
                     /pseudo
     CDS             1..773
                     /locus_tag="VQ878_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(1089..2063)
                     /gene="pta"
                     /locus_tag="VQ878_001620"
     CDS             complement(1089..2063)
                     /gene="pta"
                     /locus_tag="VQ878_001620"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET3095932.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(2107..3003)
                     /locus_tag="VQ878_001621"
     CDS             complement(2107..3003)
                     /locus_tag="VQ878_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3095933.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(3000..3818)
                     /locus_tag="VQ878_001622"
     CDS             complement(3000..3818)
                     /locus_tag="VQ878_001622"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET3095934.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(3802..4473)
                     /locus_tag="VQ878_001623"
     CDS             complement(3802..4473)
                     /locus_tag="VQ878_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET3095935.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            4601..5170
                     /locus_tag="VQ878_001624"
     CDS             4601..5170
                     /locus_tag="VQ878_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET3095936.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            5283..6242
                     /locus_tag="VQ878_001625"
     CDS             5283..6242
                     /locus_tag="VQ878_001625"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3095937.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            6252..7367
                     /locus_tag="VQ878_001626"
     CDS             6252..7367
                     /locus_tag="VQ878_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3095938.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFTNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            7372..7719
                     /locus_tag="VQ878_001627"
     CDS             7372..7719
                     /locus_tag="VQ878_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET3095939.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKEVTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            7727..7942
                     /locus_tag="VQ878_001628"
     CDS             7727..7942
                     /locus_tag="VQ878_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3095940.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            8025..8666
                     /locus_tag="VQ878_001629"
     CDS             8025..8666
                     /locus_tag="VQ878_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET3095941.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            8684..9373
                     /locus_tag="VQ878_001630"
     CDS             8684..9373
                     /locus_tag="VQ878_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3095942.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(9370..10050)
                     /gene="radC"
                     /locus_tag="VQ878_001631"
     CDS             complement(9370..10050)
                     /gene="radC"
                     /locus_tag="VQ878_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET3095943.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(10093..12384)
                     /gene="pcrA"
                     /locus_tag="VQ878_001632"
     CDS             complement(10093..12384)
                     /gene="pcrA"
                     /locus_tag="VQ878_001632"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET3095944.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQNCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDTDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(12575..13380)
                     /locus_tag="VQ878_001633"
     CDS             complement(join(12575..13003,13006..13380))
                     /locus_tag="VQ878_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3095945.1"
                     /translation="MNDEASKQLTDARFKRLVDVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADLGIHESNLIRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKTNRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNFIAGIINHELGF"
     gene            complement(13760..14620)
                     /locus_tag="VQ878_001634"
     CDS             complement(13760..14620)
                     /locus_tag="VQ878_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET3095946.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(14636..15913)
                     /locus_tag="VQ878_001635"
     CDS             complement(14636..15913)
                     /locus_tag="VQ878_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3095947.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(15906..16457)
                     /locus_tag="VQ878_001636"
                     /pseudo
     CDS             complement(15906..16457)
                     /locus_tag="VQ878_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(16473..17732)
                     /locus_tag="VQ878_001637"
     CDS             complement(16473..17732)
                     /locus_tag="VQ878_001637"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3095948.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         5432 a         3902 c         3262 g         5292 t
ORIGIN      
        1 ccctcgtatc atcaaccaaa agattgctca aaagttaatt gaaaagattt ctatgactga
       61 tattgcccat cagctttcca tctcaacttc aactgttatt cgtaagctca atgattttca
      121 ctttgagcat gatttttcgc gtcttcctga gattatgtct tgggacgttg aaacagtccg
      181 gggagtgact gtttcaatcg ggagatggag atgagcttta ttgctcagga ctttgataag
      241 ctcaatatca taactgttct tgagagcaga acacaagcca tcatccgaaa tcccatgaat
      301 acaaggctat caagcgctac tggaaactca ttcaacagga tagccgtaaa ctgagtgata
      361 agcgatttta tcgtcctact tttcgtatgc atttaaccaa taaagagatt ttagacaagc
      421 ttttgagcta ttcacaagac ttgaaacatc actatcagct ctatcaactc ttgctgtttc
      481 actttcagaa taaggaaccg gagaaatttt tcggactcat tgaggacaat ctaaagcagg
      541 ttcatcctct ttttcagact gtctttaaaa cctttctaaa ggacaaagag aaaatcgtca
      601 acgcccttca actaccctat tcaaacgcca aattggaagc gaccaataat ctcatcaaac
      661 ttatcaagcg caatgccttt ggttttcgga actttgaaaa cttcaaaaaa cggattttta
      721 ccgctctgaa tatcaaaaaa gaaaggacaa aatttgtcct ttctcgagct tagcttttct
      781 tcaacccact acagttgaca aagagccaga aaacgcataa tagcaggtgt caagacactt
      841 aatattatgc gttttctcat gaaaaaattc tcttttcata ctcatttaaa atcaaaaagg
      901 gaaattatcg ttttacggac atacatatta cagatttcta taggtcgtgt atagacagga
      961 tatcatcgct tggaagtttt cctttttgac accaatcagt aatttagttc tcaggaatta
     1021 atggcagtgc ttttcgtaca tagtttcata actacagtat agcatagtat atcgctttat
     1081 agttttcact attgatgaac tgcttgagct gctgtgatga gggtcaactt gtaaacatca
     1141 tctgcattac atccacgaga aagatcatta actggcttgt ttaaaccttg caaaacaggt
     1201 cctacagccg caaagccacc caggcgttca gccatcttgt aaccgatatt tccggcctcg
     1261 atacctggga agatgaagac atttgcttga ccagctaccg tacttccagg agctttcaga
     1321 gctgcagttt caggaacaaa ggctgcatca aattgcaact caccatcgat ttcaaggtca
     1381 ggacgcaagt cgtgagcaat tttagttgct tcaacgacct tatcaacgct ttcaccaaac
     1441 cctgaacctt tagtagaata gctcaacatg gcaattttag gttcgatgcc aaacatctta
     1501 gctgtgattg ctgagttgat ggcaatttca gccaaggctt ctgcatctgg attgatgtta
     1561 atggcacagt ctccaaatag gtaacgttcc gtaccacgaa ccatgaggaa ggctcctgaa
     1621 gtacgagtta catttggacg agttttgatg atttgtagag ctggacgaac tgttgaagct
     1681 gttgagtgaa tcgctcctga caccattcca tcaaccaagc ccaagtaaac caacatcaca
     1741 ccaaagtagt tgacatcttc aaccaaaacc ttgcgtacat cttcttcagt cattttgccc
     1801 ttgcgacgct ccaccaaggc agaaaccatt tcttcaaatt gaggataatg ttgagggtcg
     1861 atgacctcat aaccatccat gattccttca atttcaagat aaattttaat tttttcagga
     1921 tttccaagca aaacaggaat cacttctgtt tcttttacta agcgttttgt tgcttgaaga
     1981 atacgaggct cttccccttc agggagaacg atacgagcat ttttaccaac aaggttggct
     2041 ttgagacttt caaaaacttc catgagtttt ctcctttaag ataataatta tactctgaga
     2101 cagtttttat agagtattag ttgataactg ggtaataagg ttactgaaat catccggcaa
     2161 gggactttct aactgcaagt cttgctctaa aaatggatga taaaaggata ggtaatggca
     2221 atgcagagcc tgacgttgaa taccatcttc cagactacca ccatacaaat catctcccag
     2281 caaaggaaaa ccgatatgag aaaaatggac tcggatttga tgggttcgac cagtgtgcag
     2341 gtgaatatag accaagtgaa tatttccata agaagctaca atcttgtatg aagtatgggc
     2401 atactttccg cctttagcca ctcgtctggt aataatggaa tcttcatcac gcgcaatcgg
     2461 agcaataatt tccccttctg gctccaaatg tccatctccc ttaaccaaag caaagtagcg
     2521 tttctcgata gatttcttct gcaactgctt gtctaatcgt gcatgggcat aaccgtgctt
     2581 ggcaaagagc atcaagccag aagtgtccct atctagtctg gtaacaatgt gaacctgctg
     2641 attttcataa ttttgcttga catagtaacc cttgataaaa ttggcaatgg tgttagagtg
     2701 attgacacta ggaatagaag ccactccata gggtttattc aagactagaa agtggtcatc
     2761 ctcatagaga atatctaatg gatgctcaat agcctccaag gtttcaaagc cttcctcagc
     2821 gggaatgtaa atggtaacgt agtctccaac gtccaataga tacgttgcat tttgcggttg
     2881 attattgacc agaatagctc cacctcgaaa cttaatctta gccagcaatc ccttagaaac
     2941 ctcgtgcttt tttaaaaagg tcttaacctt gacatgttca tctgcgataa attcaaacct
     3001 cattcatcca cctcaccgat aaaggcatcc ttaacacggt tccagaaact ggtatggcta
     3061 ggagtcgcga caaagtgaat cttatgatgg tcgatttgat actcaatacg ctcaatatta
     3121 cggaaagaat aaacgctatt gtcaaccgaa atagtatgat aatcgtttct tgttggaata
     3181 agttcaatct tatccttctt aggcacaata atggaagagc ccagtgttcg ataaacacga
     3241 ttattaaggc tggcaatttc cgttaattgc aaagcttcaa tggtagggtg taaaacagca
     3301 ccgccaagag acttgttata ggcagtacta ccagtcggtg tcgaaactgt tagcccgtct
     3361 ccacgaaaac gttcaaaggg aacaccattt attacaatat ctgccaccat ggttcgatca
     3421 gacctgcgga tgctggcttc gttgagtgct ctgaaaatct taacttcacc attttcaaga
     3481 aagaccttca cattcagaac agggtaagaa acccttgccc cagtatctag ctgcaaatta
     3541 gtcactagct tgtccaactc aaaatcacga taatctgtat agaagcccaa atgtccagta
     3601 tgaagaccga taaagcggac cttgtcaagc tgattttcgt acttatgaaa ggccgacaag
     3661 agcataccat ccccgccaat ggaaatgaca atatccggat tggtatcatt gagtataaac
     3721 tgatttctct tcaaacgatc tcgcaattca tacaaaaccc tttgactctg cggttttcta
     3781 ttggctatca gatcaattcg tttacctgta ttcttcatct gtatcgtcac tgtttcctac
     3841 accgtcattt aattttctac tcaaaggatc aaaaagtgcc tgggcttctt ggatatcatc
     3901 acgaatttca cccatttctt catccaactg atgggcgatt ctagctgtaa tttccagtcg
     3961 cttcttaatc tcatctggga aatccccttg gtacttgtag ttgagagaat gttctatcgt
     4021 tgcccagaaa ttcatggcca aagtacgaat ttgaatttct gccaaaatag tcttagctcc
     4081 attgatggta tcaaccgtat attctactac cacatgatag gaacgatagc ctgatgcttt
     4141 tctatgagta atgtaatctc gctcctgtat gattcgcata tcctgacgct tgtgcaaaat
     4201 atccactact tccttgacgt catctacaaa ctgaaccatc acacgtaagc cagcaatatc
     4261 ctgcaaatcg tgttccaagg tcgcataagt aatgccacga cgagccattt tttctttgat
     4321 gctctcaatt ggcttgactc gaccggtcac aaactcaatt ggagaatgct tattttgctt
     4381 acgatattgc ttacgaatac cacgaagttt aatctttaac tcaccaacag cttgaatgta
     4441 aggatctaga aattcttccc attctaaggt catatattct cccttgttct catattatcc
     4501 gtcaaaaata tctttgattt tttctccaga ttcatataca ataaatacaa tgcttattat
     4561 accataaatc cgctttcaac gataaaaaaa ggtaagaaaa atgaaacatt tagaaattga
     4621 attgaaaaca ctattgaaaa aagatgaata caatcgtcta aaagaccagt tcacaggtgt
     4681 cactcctgtt cttcaaacaa attactacat cgacacgcct gattttgaac tgcgagaaaa
     4741 gaaagtcgct atgcgcattc gaacctttga agactgggct gagttgacac tcaaagtccc
     4801 gcagagtgtt ggaaacatgg aatacaacca aaaattgcaa ctaaaagatg ctgaggacta
     4861 tctgagtaag gaagaacttc ctcaaggact agtactggat gaattggcga aacatggtat
     4921 ccaaagtaag aactggcagg ttcttggttg tctaacaacg cttcgctatg aaatgaaaac
     4981 agctattggt ctcatggcac tggatcagag ccgatacttt gatataacag attacgaatt
     5041 ggagcttgaa gtggaaaatc atgagcaagg caaacaggat ttccgacaat ttttagagaa
     5101 aaatcagatt tcctaccaaa aagctccttc aaaattggtt cgatttgtca aaagtatgaa
     5161 aaatagctga aataatctcc attttttggt aaaatagaaa agataaaaat acacaaatcc
     5221 cagttcatat atgtaaggta aatataacta ggatttataa agtttacaga ggacggtcta
     5281 taatgtcaga tagaaaaaac atgaaacttt tcgcactcaa ctctaaccaa gagattgcac
     5341 aaaaaattgc ccaagctgtt ggtgtcccac ttggaaaact atcatcacgt caattttcag
     5401 acggagaaat ccaagtaaat atcgaagaaa gtgtccgtgg ttatgatgtt tacatcatcc
     5461 aatcaacaag tttccctgtc aacaaccacc taatggaatt gttaatcatg gtcgatgctt
     5521 gtgtgcgtgc aagtgcccac agtatcaacg ttgtccttcc atattttggc tatgcacgtc
     5581 aagaccgcat tgcttgtcct cgtgagccac ttacagcaaa actagttgcc aatatgctgg
     5641 ttaaggctgg agttgatcgt atcctgactc ttgatttgca tgccgttcag gttcaaggtt
     5701 tctttgatat tccagtggat aatcttttca ctgttcccct attcgcaaaa cattactgcg
     5761 ataaaggatt gcttggttca gatgttgttg tcgttagccc taaaaattca ggtgtcaaac
     5821 gtgcgcgtag cctggctgaa tatcttgatg ctcctatcgc cattatcgac taccctcaag
     5881 acgatgcaac tcgtaacgaa ggttatatta ttggtgatgt tgaaggtaag aaagctatct
     5941 tgattgatga tattttaaat acaggacgta ccttctctga agcttctaaa atcgttgaac
     6001 gtgaaggagc tacagaaatt tatgctgttt ctagccacgg tctcttcgtc gagggagctg
     6061 ctgagcttct tgacaatact aatattaaag aaattcttgt gactgattca gtagcaacaa
     6121 aagaaaaaac tcctaaaaat gtatgctata tcactgctag tgagttaatt ggtgatgcta
     6181 tcgtacgtat tcacgaaaga aaaccagtca gcccactctt tgcctacaat aaaaagaaat
     6241 aaggtgattc tttgatttat ttggacaatg ctgcaacgac tcctatgtca gcagttgcta
     6301 tttcagctat gaccaaggtt atgcaagaaa cccacggaaa tccttctagt attcatggtc
     6361 atggtcgtca agctggcaaa ctcttgcgag aagcccgtca ggaactagcc cagttactaa
     6421 ggacaaaacc tcaacatatc tttttcactt ctggtgggac tgaaggcaat aatactacca
     6481 tcattggcta ctgtcttcgt caccaagaac aaggaaaaca tatcatcaca actgccatcg
     6541 agcaccatgc tgtccttgaa acaattgatt acttggttca acactttggg tttgaagcaa
     6601 ccattatcca gccagaaaat caagaaatca cagcccagca aattcaaaag gctttacgtg
     6661 acgatacgat tttggtttct accatgttta ccaataatga gacaggaaac ctactgccca
     6721 tcgctgaaat tggccaaata ctcaagcaac accctgctgc ctatcatgtt gatgcagttc
     6781 aggctattgg taaaatccca attcattcag aagaattggg cattgatttt ctcactgctt
     6841 ctgcccacaa attccatggt cctaagggaa tcggttttct ctacgcatct agcatggact
     6901 ttgattccta tctacatggc ggagaccagg aacagaaaaa acgtgcagga actgaaaatc
     6961 tgcctgctat cgtaggcatg gttgcagccc taaaagaaga cctagaaaaa caagaagaac
     7021 attttcaaca tgtacaaaat ctagaaactg cctttctggc agagctggag ggcattcagt
     7081 attacttgaa tagaggaaaa catcatctcc cttatgttct caatattgga tttcctggtc
     7141 agaaaaatga cctcttactc cttcggctag atttagctgg aatttcaatc tctactggct
     7201 cagcctgtac tgcaggcgtt gtccaatcca gccatgttct tgaagccatg tatggcgcaa
     7261 attcagaacg cttgaaggaa tcccttcgca tcagtttgtc gccacaaaat accgttgaag
     7321 acctacaaac cctcgcaaaa accttaaaag aaattatcgg aggttagcca tatggcattt
     7381 gaaaaaatca ttcagttaaa aaattgtcgt tacgattaca ctcttagccc ttctgttaaa
     7441 aaattcaccc tcaaagataa cacctttttt gaaactaagg ttggtaacta tgaactgact
     7501 cgccttttgg aaaaagtgcc aaacagcggt gaaggcttcc aactcaaaat catcattaac
     7561 aaggaagtta caggggctaa aatcaatatc actgataagt ttggccttcg tctagttgat
     7621 attttcaaat cagaagacca ccatattcat caggaaaaat tctacttcct catggatagc
     7681 ttggtagaac gtggtgtctt tacaaaatcg gaaagataga gccaaaatgt ttgaactgac
     7741 ctataaggac tgctatcatg tagagcgtac tctcaagtat gaggatcatg aggctctcat
     7801 gttgactttg tcaggatgtg taaccttacc agatacactt tatgtgactt ctctgacttt
     7861 taggggccaa aaagtttatc agggtctggt cggagacctc taccgttttc tatctcatgc
     7921 agatttttta catcaaaact aagatttttc ttagtttttt cttatttttg ttgatttttt
     7981 cacaatgttt ctataaaata gaagaataga aaggttgtga ttttgtgaaa gataaacagt
     8041 ttgctattcc aaaagctaca gcaaaaagac tctctctcta ctatcgaatt tttaagagat
     8101 ttcatgcaga aaagattgaa cgtgccaact ctaagcaaat tgcagaggct atcggtattg
     8161 attcagcgac cgtacgtcgt gatttttcct attttggtga acttggtcgt cgtggttttg
     8221 gatatgatgt caaaaaacta atgacatttt ttgccgattt gctcaatgac aactctatta
     8281 ccaatgtcat gctggttggt attggaaata tgggccatgc ccttctccac taccgcttcc
     8341 acgaacgtaa caagatgaag attatcatgg cctttgacct agatgaccat cctgaagtcg
     8401 gtacccaaac tcctgacggg attcccattt acggaatttc tcagatcaag gataaaatca
     8461 aggatgctga tgtgaagact gctatcctaa ctgttcccag cgtcaagtca caagaggttg
     8521 ctaatctctt ggttgatgct ggtgtgaaag gaattctcag tttttcacca gtccatctgc
     8581 atttaccaaa agacgtggtc gttcagtatg tcgatttgac aagtgaactc caaaccctcc
     8641 tctacttcat gcgaaaagag gattagaaag cgaaaatcat tttatgaaaa aaccagttat
     8701 tgggattaca ggaaacgaaa aaactcatcc agatgatgac atcatgatga gctacgcagc
     8761 aaaaggcttt gttgaaggcg ttaaagatgc tggagggatt cccatcatcc taccgattgg
     8821 tgatcaagaa atggcctgcc actatatcag tttgattgac aagctcatct tgacaggtgg
     8881 gcaaaatgtc gatccaaaat tctatggcga acccaaaacc attgatagcg atgactatca
     8941 ccttcaaaga gatatcttcg aactggccct catcaaggaa gctattaaac agaaaaagcc
     9001 cattttctct gtctgccgtg gtacccaact ctttaacgtt gccatgggtg gaactttgta
     9061 ccaagatatc gaagaccatt ggcaggattc ttctgttgag tacacaactc aacgcttggt
     9121 gacagaacca gataccgttc tccaagaaat ctatggagaa atctctcata tcaactcctt
     9181 ccaccaccag agcatcaagg acttagcacc aaatttaaaa gttgtggctc atgatcctaa
     9241 agatggtatc attgaggctg tcatgagtac ggatgatgtc gcctttctcg gtgtccaatg
     9301 gcatccagaa cttctttttg aaaatcgtcc caaagataaa aaactctttg actatgtcgt
     9361 taatgaactt tagattaaat ctgtcttttc acgataacta aagtaattag aatgagagac
     9421 aatcaaatgg tccaagagaa caatccccat cagttcgcag gcttctttaa caagtttagt
     9481 gacatgatca tcattttggc taggcgctac cgctcctgaa ggatgattgt ggaccaagat
     9541 aagagaagtc gccatatgct tgattgcata gtgcagaatc tctcgcggtt cagcgatact
     9601 acgagttaca gaaccgataa aaatggtctg ctgatggatg atttgatttt gagtattgag
     9661 atagagtgcc accaggtgct cttgtttttt atcccctaat tcctgctgca tcttcttggc
     9721 caacttttga ctgctgagaa tactttccat ttcaagagtc tcgtgtttgt gaatacgatg
     9781 ccccagttca atcatagctt gtaattctat ggccttaaca cgcccaatac cagacaaact
     9841 ctgcaattcc tgcagggtca tttttttcaa atccgttagg cttgaaagat tgttcaagac
     9901 tttttgggca atttcaaaaa cgctagcttg acgtgttcct gtcctgagta aaatagctag
     9961 caactcttgg ttactaagcg cttcaactcc ttccttggcc agcctttctc ttggtaatag
    10021 tgaatcttct tggaatgaaa tactgtacat aaaaatcctc ctcactttat tattcgtgag
    10081 aaggatggaa aattagattt ttttctcaat tggagccaca ctggctaaaa gttttttcaa
    10141 acctacttct gggaaattga ttttcaattc ctgcctagca ccgctacctg aaacttccag
    10201 aacagttccc tctccccatt tcttgtggag agcaatgtca ccaatggacc aatttgcctc
    10261 gctagatgct gattttgcgc cagctgtaaa ttgaccaaat ggaagaccgc ttgactggat
    10321 tgattttggg gcagcaccgc gtttacggtc ttgaagagcc tgagccaaac tcataccttg
    10381 accaaaggaa atactaccac tgctatatga tgccttaaag cttgtatttg caggacgagc
    10441 cagaccttga tactcaagca agtctgaact gatttcgtta ataaaacgag tcggacggtt
    10501 ataattggta cgaccaaaaa gcaagcgtga gttggcattg gtcagataga gaattttctc
    10561 tgcacgcgtg atacctacat aggctagacg gcgctcttct tctaattcat ctgtatcttc
    10621 agtcgcacga ctaagtggaa agacattttc ttccatccca atcaaaaaga caactggaaa
    10681 ttcgagacct ttggcagcat gcagggtcat caaggtcact tctgatgtct cctgactacc
    10741 tgaatctgtg tcggcaatca aagccaagtc atttaagaaa cgactcagtt tgtccagacc
    10801 agtttcctct tctgtcacat cagtggtgtc atcaaagttc ttcgtaacag aaagaaactc
    10861 ttcgatattt tcaacccgtg ccttgctttc tagagtcgct tgggcgttaa gaatatcgac
    10921 ataacctgtt ttttctagga cggactcaac caactctgta atgcttaagt ggtctagctg
    10981 ctcccgcaaa tcaagcatca tattggcaaa atcccagata gattgggctg ccttaccctt
    11041 gataccagac aacataatat tagcagaagc atccagcata gacatatttt gcaaatttgc
    11101 aaaatcacgg attttctcaa ctgtacctgg accaattcca cgtttaggct cgttgataat
    11161 acgctcaaaa ctaatattgt cactcaaatt agcaataagg ttgagataag caataatatc
    11221 gcgaatttcc ttacggctgt agaatttggt tccgccaacc atggtataag gaatgttaga
    11281 cttgagcagg gcttcctcaa ttgtacggga ctgggcatta gtccgataga gaactgcaaa
    11341 atccttatga aggaagtttt gactgcgact aagttcatcg atggttctgg ctacaaatac
    11401 agcctcatcc agctcatcat cggcacgata gtaaacgatt tgctccccat cagcgttttg
    11461 agtccagaga tttttaggac ggcgattttt attgttttta ataacctcgt tggccgcttg
    11521 gagaatggtt ttggttgagc ggtaattttc ctccaacaaa acaaccttgg ctttggggta
    11581 atccttttca aagtccaaga tattctgcat atcagcacca cgccaaccgt agatagactg
    11641 gtccgcatcc ccaaccacac agatattttt aaaacgggaa gccaagagtt tgaccaattg
    11701 gtactgagcg tggttggtat cttggtactc atcaacgtgg atgtattgga atttttgctg
    11761 gtagtaggtt aaaacatcag gattttgatc aaagagacgc aaggtcagca taatcaaatc
    11821 atcaaagtca acggattcag actgacgaag ttctttttga taggctgtat aacactgggc
    11881 cacaatttgc gtatacatat cgccagcttg ggcagcataa gcaacatcat caatcaaatc
    11941 attcttagca ttggaaatgg tccccaaaat agttcgttca ttccattttt taggatccaa
    12001 gttcaactgt ttgagaatac gtttcatgag cgttcgctgt tcaccaggat ccacaattgt
    12061 aaaattacga ttgtagccaa tatggtccgc atcgcgacgc aaaatacgca cacacatgga
    12121 gtggaaggtc gcaatcagac agttctgagt agctggattg agactataag cacgctcttt
    12181 catctcacgc gcagccttgt tggtaaaggt aatggccaag atattccaag gattgaccag
    12241 cttttcatca atcaaataag cgatacggtg ggttaaaaca cgagtctttc cagaaccagc
    12301 ccctgccatg attagcaagg gaccttctgt cgtttgcacc gcctcagcct gacggtcatt
    12361 cattccattt aataatgcgt tcatcttctc ttccttactc ttgaagtcaa tatttctatt
    12421 atatcagaaa tcagggaaaa tagaaacttt acggggagta gcaaaatata gtggattgaa
    12481 actagaatac tacactgtgg gtttctaaaa cactcgactt ttcacccaat tttttcataa
    12541 actagctcaa tacctcaata gacttcctgc aaaactagaa tcctagttca tgattgataa
    12601 taccagcaat aaaattcatt cgtaatccga agcgtttacg atgatttcga taagttgttg
    12661 aaaacatttt aaacgttttt actttggcaa agatgttctc aaccttgctt ctctccttag
    12721 atagcgcatg gttataagcc ttatcttcaa ctgttagcgg cttgagtttg ctggatttac
    12781 gtggagtttg tgcttgagga tatattttca tgagcccttg ataaccactg tcagccaaga
    12841 ttttaccagc ttgtccgata tttctgcgac tcattttgaa caacttcata tcatgacaat
    12901 agttcacagt gatatccaaa gaaacaattc ttccttgact tgtgacaatc gcttgagcct
    12961 tcatagcgtg aaatttcttt ttaccagaat aattggccag ttgatttttt tagggcgatt
    13021 ggtttttact tccgtcgcat caatcattac cgtgtcctca gaactgagag gagttcttga
    13081 aatcgtaaaa ccactttgaa caagagttac ttcaacccat tggctccgac ggattaagtt
    13141 gctttcgtga ataccaagat cagccgcaat ttgttcataa gttcgatatt ctcgcacata
    13201 ttgaagagtg gccataagaa ggtcttctag gcttaattta ggttttcttc caccttttgc
    13261 atgtttaagt tgataagctg tttttaatac agctaacatc tcttcaaaag tggtacgctg
    13321 aacatcaaca agacgcttaa atcgtgcatc agttagttgt ttacttgctt catcattcat
    13381 agaactacta taccatgttt tgtttcgcag gaagtataat ataaaaaaat aaatttaaga
    13441 ttggcaatac gaacgttaaa cagaattcca tttctctttt tagaatcaaa acgacaatat
    13501 tgtggaatct ctacaggaac aatagactgc gacactaaaa tatcctccct tagttttact
    13561 ttactaatag tatataggag gagagccctg aatcctagac cctttgttat gatgcgctta
    13621 caaacagagt tggaaaaaat cttaaaagca gaaaaacgca tgatatcagc ccctaacact
    13681 tgatacaatg cgttttatta tgaaaagatc tactggattt tttatcaaaa taaacttcca
    13741 gtagtctttt cactttttat taataagttc cttcttcacc ttggctagtc aagataacag
    13801 gtccatcttt cgtaatgaca aattggtgtt catactgaca tgacaatcca ccgtcaatgg
    13861 tcttatgcgc ccaaccagtt ttcatatctg tatcaatttc ccaatcgcct gtattgatca
    13921 ttggttcaat ggttaagacc attccttcac gaagacggag tccacgacct gcaataccat
    13981 agttaggaac cattggttct tcgtgcatag ttgggccaac accatgacca accaaatcac
    14041 gcactacacc gtaaccacga ctttcagcgt attcttgaat agccgcaccg atatcaccga
    14101 tacgatttcc aacaacagct tgctcaatac ccttgtacat agcttctttg gttacatcca
    14161 tcaagttttt gacttcttcg gacggtgtac caacagcata agcccaacat gagtctgcta
    14221 aaccaccaga atagctctga gtatattttt tcatttgttc aacattgttg aagtttaatt
    14281 ttgagacatt caggtcagat ttagcaatgg gacctcccaa aaccatatca actttgagca
    14341 aatcaccatc tttcaagata taatgacgag ggaaagcgtg agccacttca tcgttaagag
    14401 agcaacaggt agcataagga tagtccatca tggcaccgtc aaccccaatc tgaagtggaa
    14461 ggaaattttc ttctttacaa cgacggcgga catattcttc aacttcccac atatctacgc
    14521 ctggcttaat caaatcacgt aagcctatat gaatacttgc tagaaaatca ccagccttgt
    14581 ccatagcttc gatttcacga gctgatttta atgttatcat cttttctcct agtttctaat
    14641 taattttaac agtcacattt gcttttgaaa caatctggtg accatgataa atatcgtaat
    14701 caattatagc tgaccgtctc gtatgatgaa taatccgtgc ctgaatgcgc aatatatcat
    14761 ctatctgaac agcctgcaaa aagtagatca gcatctgctc gataatgaga ttgcgaccac
    14821 tattaacaac taaatcttgg gtcatgtggg tcagaatttc tgccaataca ccattagcca
    14881 aaactccatt tttttctagc ataaagggtt ccactgtaat gactacttca tcatggtgat
    14941 aagagagctt ttgtccaatc tgctcagaaa aagttggtag agccgaaact tgggaacggc
    15001 tcatcttctc catgacatct cgtcgcgtca caacgccaag caaagtttga ttgcttcgaa
    15061 caactggtac catttcaaag tcttctgcga tcatccgttg actcacattg gcaatatttg
    15121 tcgataatcc aaccaaaaat agactacgag acataacctt atcaattgtc gtgcttggtg
    15181 atttatcacc agcgtctctc atggttacaa cgccaacaac gacctgatgt tgattgataa
    15241 cagggaaacg gctgctacga ttcttacgaa ccaagtccaa ataatcttta actgtatctg
    15301 tctctctcag aaaaccatac tcatgactag ggcgataaag tttctcaact gtcagaatat
    15361 cagtcttgat ttggacattt gacaaggctt tattgatcat ggtcgcgacg gtaaaggtat
    15421 catgcttact tcttagaaca ggaatccctt tttgattggc cagtttaagc acatcatcat
    15481 gaacctgaaa tccccctgta accagaactg cattttcatt ttccaaggct agcaactgaa
    15541 tacgggttcg gtctccgaca atcaagagcc ccccatcatg aaggtaagac aagatatttt
    15601 gttcagtcat ggcaccaatt gaaaacttac taaattctct ctctaaacct tcttgcccag
    15661 ccagaacctc agaagaagtc acttctgcaa tttcagcaaa cgttaatctc tctatagcaa
    15721 ctttctggga tttaacacga attgttccac ttctaggacg ggtctccaca attccacggt
    15781 tttcagcttc tttaatagcc cgataggctg ttccatcact aactcctaga tgattcgaaa
    15841 tgctacgaac actgaccctt ttacctactg gtaattcctc caaatagctt agaatttcct
    15901 gatgcttact cattgaactc tccttttaca taccgaaatt caagataatc ccgcattttt
    15961 cttgtgtaac gatcacttcc cttaaactga cggaacaaac taaatccaga cttaagagca
    16021 actctttggc tagcttcatt ttcaaggtgg gtaatgatag ataattgttt taagccaaat
    16081 tcctcaaaag aaagctgaca aatttttcta acaacctctg tcataaatcc ttgcgaccaa
    16141 gcatcttttc tcaaaaaata gccaagctca gcttcttttt tgatttaatc taacttctca
    16201 aatttaatag aaccaatcat ttgttgattt ttctggtcac aaattgccca cactcccaaa
    16261 ggggacttca taaagtaatt ggccagtgca tattgacttt cttccagact tgcctgcgtt
    16321 gggaaaataa attgaagatt ttctggattt gaagctatct cgcggaagtc ctgactatca
    16381 ctaaaaaaga aaggacgcaa atacaagcga tccgtttcaa aaaaagaaaa cattgctaat
    16441 ttggtccaaa tattcataaa cacctctacg gtttaatcct caacaagtct aatatccgct
    16501 cctaaattac gtaatttttc gataatatca gaataaccac gtaagataaa ctcgatattg
    16561 gtaatttcag ttttaccttc agccataagc ccagcaatga ctagtgcagc cccagctctt
    16621 aagtcggtcg ctttaacact ggccccacgt aaatcacgtc cacccgtgta caaaatatga
    16681 ccatttgttg tcgaaatatc cgcatccatc tttgctagtt caaaaacatg atttacacgt
    16741 ttttcgtaaa tcgtatcgac aattgtacca cgaccattcg ctcttagtaa aagaggggta
    16801 agcggttgtt gcaaatcagt tgcaaagcct gggtaaggag ctgtcttaat attgattgct
    16861 ttcaaattag actgttcctc gacaaaaatg ctgtcttcag atacagtcat tctcactccc
    16921 atttcttcca acttagcaat aaacccttcc aggtgttcgt aaagaacatt atttatacga
    16981 attcctttac caactgcagc agctaaagat atatatgttc cagcttcaat gcggtctgga
    17041 atcacctgat gacgtgtccc atgtaatctt tcaacaccat caataatgat gatattagtt
    17101 cctgccccac ggatatgggc acccatatta ttcaagagag tagctacatc aataatctca
    17161 ggttcacggg ctgcattttc aataatagta cgaccatttg ctttaaccgc agcaatcatc
    17221 gtattaatcg ttgctcccac actaaccgta tccatgtaaa tacttgcacc atgaagtcct
    17281 gtatctttag cagataactt catgttatct ccctcgtagc tagcagtggc acccatagct
    17341 tcaaacgcct taaggtgtaa gtcaatcgga cgaggaccaa gatcacatcc tcccggtaga
    17401 ccaactgtcg cttcaccaaa acggcctaag aggctcccat aaaaatagta agatgcacga
    17461 agactgttaa ttttaccata aggcattgga atattttgaa cacctcttgg atcaatctcc
    17521 aagacatcgt cataacgctt aacagtagct cccatcaatt ccatgatttc gacaagactg
    17581 gctacatccg aaatatctgg aacacaatcc aaagtcacca catcatcagc caagataata
    17641 gctggaatta aggccacaac actattttta gcaccactaa tagtaatttc accttgcagt
    17701 ggtaatccac cattgataac aatttttctc attctaagtt ttcaatactc tttcaagatt
    17761 tctaataagg tcttcaaaat aaagtatatc ataaatttat ccttttttcc atccttttca
    17821 attttattgg ataaatcaga gttgacgagt tagtaactga attactaata ctcaataaaa
    17881 atcaaaga
//
LOCUS       DAVBOM010000046        17238 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBOM010000046 DAVBOM010000000
VERSION     DAVBOM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.046"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(225..515)
                     /locus_tag="VQ878_001638"
     CDS             complement(225..515)
                     /locus_tag="VQ878_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3095949.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQISERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(503..755)
                     /locus_tag="VQ878_001639"
                     /pseudo
     CDS             complement(503..755)
                     /locus_tag="VQ878_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            959..1036
                     /locus_tag="VQ878_001640"
                     /pseudo
     CDS             959..1036
                     /locus_tag="VQ878_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(1154..2038)
                     /locus_tag="VQ878_001641"
     CDS             complement(1154..2038)
                     /locus_tag="VQ878_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3095950.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(2183..3334)
                     /locus_tag="VQ878_001642"
     CDS             complement(2183..3334)
                     /locus_tag="VQ878_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET3095951.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(3480..5246)
                     /locus_tag="VQ878_001643"
     CDS             complement(3480..5246)
                     /locus_tag="VQ878_001643"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET3095952.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(5303..8419)
                     /locus_tag="VQ878_001644"
     CDS             complement(5303..8419)
                     /locus_tag="VQ878_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3095953.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(8429..10723)
                     /locus_tag="VQ878_001645"
     CDS             complement(8429..10723)
                     /locus_tag="VQ878_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3095954.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(10782..11582)
                     /locus_tag="VQ878_001646"
     CDS             complement(10782..11582)
                     /locus_tag="VQ878_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3095955.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(11579..12352)
                     /locus_tag="VQ878_001647"
     CDS             complement(11579..12352)
                     /locus_tag="VQ878_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3095956.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(12377..12847)
                     /locus_tag="VQ878_001648"
     CDS             complement(12377..12847)
                     /locus_tag="VQ878_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3095957.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(12838..13269)
                     /locus_tag="VQ878_001649"
     CDS             complement(12838..13269)
                     /locus_tag="VQ878_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3095958.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(13262..13702)
                     /locus_tag="VQ878_001650"
     CDS             complement(13262..13702)
                     /locus_tag="VQ878_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET3095959.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(13714..14352)
                     /locus_tag="VQ878_001651"
     CDS             complement(13714..14352)
                     /locus_tag="VQ878_001651"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET3095960.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(14467..15870)
                     /locus_tag="VQ878_001652"
     CDS             complement(14467..15870)
                     /locus_tag="VQ878_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET3095961.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            16046..16819
                     /locus_tag="VQ878_001653"
     CDS             16046..16819
                     /locus_tag="VQ878_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3095962.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
BASE COUNT         5321 a         3649 c         2559 g         5709 t
ORIGIN      
        1 gtggatgttt ctggtctaaa gtcatctgaa tctttgagat gagctttata aatcgctttt
       61 ttcagttttt gcactggtgt ttcgataaac tcaaactttt tagccgtggt attgcctgat
      121 tttatagtat attgaaacta gaatagtaca cctctacttc taaaacattt ttagaaatcg
      181 atttgactgt cctgatcgat ttgtcctgtt cttatttcat tttactatat ttgagccact
      241 tcgtctttaa cggctttatt cataagctct tgtaattttt ctttactatc aattacttct
      301 gattttccgt tgtaatttat tgtaataggt tttaacttac ctaatttctc gacacgctca
      361 gaaatttgat cttttttgaa ggctgcatat gtttttccta agattttttc gaaaatatat
      421 ttatcagata gcggtttgcc ttcttcttca gcttggtttt tgtattgatt tgaaacataa
      481 ggaacaaatc cttcatagta acctaatgct cccataagtt caaaagcttg ttttctaatt
      541 caaaccattg caactcagat ttcagctttt cagataaatc ctgctcatcc aaataatgac
      601 ttgaaattag tgctgaactc gtttctgtat cctgtacagg ctgagcaccc ataccagcaa
      661 aaaaataaac tcgttcctag caagaccgaa caagctccta ttgcatattt cctcaaagaa
      721 aaacgctgct ttctctcaaa ttgaaattct ttcatcccat ctcccatcat tcattattac
      781 tgtatatttt gtatatcaga aatagtttgt attcacaaat ctttctagtt attcccttat
      841 cattcctaat taagggagat aacatacaat aatttttagt taaatgtata tcgatgtttt
      901 ttgtttttct taataaacgc aatacaaaaa gagcctgttg ccaagctctt tatactcaat
      961 gaaaatcaaa gagcaaacta ggaaactagc cacaggttgc tcaaaacacc gttttgaggt
     1021 agtagataag actgacgaag tcagctcaaa acactgtttt gaggttgcag atagaactga
     1081 cgaagtcagt aacatctata cggcaagacg acgctgacgt agtttgaaga gattttcgaa
     1141 gagtattagt ctattatttc ttctcagcgc gaagggctga caagatttgt gtacggatat
     1201 catccacacc atttggagta tttggtaaaa agatggtttg atttccttta gaggcaaagg
     1261 tattcaaggt atccaaatac tggttggtca agaggataga catgatttgt tcttctgtca
     1321 tgccaacatt ggcttccttg agttcggtga tagactctgc caatccatcc acaatcgcct
     1381 tacgttgttg ggcaatcccc acaccatgaa ggcggtcttt ttctgcttcg gcttcagctg
     1441 cagtgacaat tttaatcttg tcagcttccg ccaattcttg tgctgcgacc cgcttacgtt
     1501 gcgccgcatt gatttcattc atagattgct taacttctgc atctggttcg accttggtaa
     1561 tcaaggtttt cacgataatg tagccgtaag tggtcatttc ttctgctact tggtgttgaa
     1621 cctcaagggc aatctcatct tttttctcaa acaattcatc caaggttaat tttggaacag
     1681 aagagcgaag agcatcttcg atataagatt taatctgaga ttctggacgt atgagtttat
     1741 agtaagcatc tgtcacgctc tgctcgttga cacggtactg agtcgctaca ttcatcataa
     1801 cgaacacatt gtccttggtc ttagtctcaa ccacaatatc actttgcaac aagcgcaact
     1861 gaatccgtgc tgcaatcgag tcaatcccaa aaggcaagcg aatatgaata ccgctattag
     1921 caaccttttg gtatttccca aagcgttcaa taatcgccac cgactgctga cgaaccacat
     1981 aaactgtact cagtgtgact atcaccaata ggagcacaca aacaatcaga aaaatcatga
     2041 aaaatattgc cataatggaa cctccacaag tatttttcta gtattatagc acatttaaag
     2101 aaggctgtgc cgtttttact gcgatttttc ctgaaatgtc aataattaga ggtgaattgt
     2161 cctattgtcg tctaatctct tgctaaaata actctttata aaaggcaatc gtttcttcta
     2221 aggttggcat aaatggattt cctggtgcgc aggcatcaat caaggcattc ttagaaaggt
     2281 attcaaagtc gaaatctttt tcttcaatac caagttcagt caatttctta ggaataccta
     2341 ctgtctcaga aagcttctca atctcagcaa tcgcataatc ggcacactct tgatctgatt
     2401 taccttccac atgaaggccc aaggctttgg caacattgcg gaaagcttct ggtacacgtt
     2461 tagcattttc acgttctata actggtagca acatggcaca gcaaacacca tgtggcaaat
     2521 tatatactgc accgagttgg tgagccattg agtgaacata accaagacca gcattattaa
     2581 agctcatacc accaaggaag atggcattga ccataccttc acgcgcttca atatcatgtc
     2641 cattttctac agcacgagga agatattcct tgataagctc aatagcacca atagacagtt
     2701 tcttggttac atcataagca ccaggtgtta ccaaagcttc aacagcgtga gtcagagcat
     2761 ccataccagt agcagcagtc agacctttag gtttggaaag catgagttcc gggtcattaa
     2821 cagagataag agcaaggcta ttcttgtcaa ccattaccat cttaaccttg cgttcttcat
     2881 cagtaatcac atagttaata gtgatttctg cagaagttcc tgccgttgta ttgatagcca
     2941 caactggcaa gcctttttta gcagacttat gaagcccttc ataatcctgt ggttttccac
     3001 catttgtagc catgatagaa atacaactag ctgcatcctg tggagaaccc ccgccaagac
     3061 tgatgataaa atcacatcca tgttcttgca aagcagctac cccatctgtg acattcttac
     3121 aagtagggtt tggctctaca tcgctaaaga tgacatattc gattccttct gtatccagtg
     3181 gttttaaagt cttaggtaaa atatcactgc cttcgatgta cttatctgtc accaaaagtg
     3241 cctttttata gccaagttcc ttgatataag gacccacttc atttacaaca ccttttccaa
     3301 taaggttgac tgccggaaca taaaatgtag ccatataatt ttcctcctgc gcctccgcgc
     3361 tatctattta acatcattat attacttttt gtattcgttt tcaattattt gtgaattgtt
     3421 taacaaatct ttttaaaagg ataggaggga cgtaagttca cctcctatat aaacaagttt
     3481 tatttatgta gtggtcccaa caactgacat gcacgatagt ctgctgattc tagatcttct
     3541 gttccaaata aggaccaatt tttaggtcta aagatatctt cctcaggtac attatgcata
     3601 ttgacaggaa ttctcaacat agaagccaag gtaatcaagt ctgctccaat gtgtccatat
     3661 gttatggctc cgtgattagc tccccaatta ttcatgacgt catagacaga cttgaaagca
     3721 ccttttcctg tcaaacgtgg agcaaaccaa gtagttggcc atcctggatc tgtacgatta
     3781 tctaaagtat ggtgaacatc ttcaggaagt tcaagtgtat aaccttctgc aatttgtagc
     3841 actggaccaa ccccttttag aagattgaga cgtaccattg ttactggcat atcccccttc
     3901 gtcaagaaac gagttgagaa tcctcctcca cggaagtatt cgcggtttgc tggtgggaag
     3961 tctgtatttt caagcatagc ctgcacttca ctttcatcca actcccagaa tggtttcata
     4021 acaggtttgc catctcgagt agcttgacct gtaccatcta atgtacaaga accagagttg
     4081 attagatgta agaagccagc tgcagcacga ccctctaaag tatatcctgt tacacgttca
     4141 acagcctctg gactccaata agtacgcaca tcagcaaaga tttgtggagt atttgttaat
     4201 agataattaa agagcataga cacaccattt agtgaatcat tctctgtcgc aaatacaaat
     4261 ggttttcgaa taccattcca gtcaaactga gtattgagga aagtttccat aaaatctcca
     4321 tttggaaaat ggtctgtcca ctgacgttga ccttggaaac cagctactaa agcatggtga
     4381 ccaactgctt cttcctcaaa accaagttca gcaagtcttg ggttaccaac cattaagtca
     4441 cgtccaatca tgaacatctt aataacaaat tcccattgtc tatctttttc ttcacggctt
     4501 aaaacaaggt cttcacggtt atggtcgaat ccttctttta cgttttcttt cacccatttg
     4561 agcgcacgtt cgaactcttc agggtcgtaa ataccacggt ccatacggcg tgtgaactcc
     4621 gtcatatcta ccgattcatt tcgcattcct aagtattctt ggaagaaatc cggatttaca
     4681 atagaaccac caatccccat cgaaacacta cccattgata ggtaagcagt gtctctcatc
     4741 aagccagttg caagagctgc ccgcgcataa cgtaaaagtt tttctttgac atcttctgga
     4801 atagctgtat cattagcttc ctgaacatct ctaccataaa tcccaaaggc tggaatccct
     4861 ttttgagtat gtgaagctag tacagctgca agatagacag ctcctgggcg ttctgtccca
     4921 ttaaatcccc aaatagcatg aggaatatct ggagacatat ccatagtttc actaccataa
     4981 caccagcatg gtgtaactgt aattgttgcg caaacatttg attttttgaa caactcatgg
     5041 gaagctgcag cctctggtac acggccaata gtagatggag aaatcacgca ttccacaggt
     5101 tccccatctg gatatttcaa tgtgcttgaa atcaaatctg ccacactttt agccatgttc
     5161 attgtttgta cttcaagtga ttcgcgtaca ccttgacgac gaccatcaat agtcggacga
     5221 atcccaatac gtggatgttg aatcatacta ttttcctctt atttttctgt ttctttcata
     5281 ctaccgatga taatttttaa aattacttat aagtataaac ctctacctct gccaaactta
     5341 aaggaattcc tgcgtttctc aaagaaattc taaccttttt tcccttcagc ccttttaagt
     5401 ctatggatag attattgctt tctaaactgt caatatgttg tttaaaaact tcatgattat
     5461 ttgaatcata tataataata tcaaaatttg ataatctctg aatttcagca tctgttctat
     5521 tataaataat taacttttct aattcttcgg tttgtgctaa atctatctcc caccatgaag
     5581 gagaatctcc tttggtatga gtcactgaat gatgaccata atctccgttt ttatttccat
     5641 caactgctag acgagaaaaa ccattgtaat ccgttgaact ctgtcgagtt tctttggtta
     5701 atgcaatatt agaaagtttc ttcggagttc tctttgaacc atagacttca acttccgcta
     5761 aacttaacgg aatagctgct gattttaatt ctattttgac tagcttagcc cctacagaag
     5821 gtacttttaa agataacaaa ccatcaacta ctttatcaaa atgtcttcta aaaacttctt
     5881 ctcctgatga agatagaaaa ataacatcaa aattagataa acgctgaggt tcggcatctg
     5941 ttctattata aatatcaact ttagaaaccg taaactcttc tcccagatcg acctgccacc
     6001 aagcgttaga atctgcctta gtatgagtca ccgaatgatg tccgtaatct ccatctttat
     6061 taccatcaac tgctaaagca gctacaccct cataattggt tgaactttga gtagctacct
     6121 tatttgtaga gactacttta tcttctgtta ttttatctat atcctcttca gattgcttac
     6181 catctgattc tctaaaaacc tctacttctg ctaaactcaa aggcactcca ctcgttagta
     6241 atttaacttt aatatacctt gctccttttt ctttgaaatc tagactaaca gattcacccg
     6301 acaaattatt aacatgtttc ttagcaactt cgtttctatt attgtcatat agaatcacat
     6361 caaaattaga tagacgttga gtctcagcat ctgtgcgatt ataaatttta acaagcccaa
     6421 ctttatccat ttttttcaaa tcgacttccc accaagaggg attatctgcc ctagtgtgtg
     6481 ttaccgaacc agagttaaaa ttaccatttc tgttaccatc cacagctcta ttagggtctc
     6541 cattgtaatc tacagaactt tgtgttgttg gttttgcata tgctatattc aaattaccat
     6601 cattaaattt atctggtgtt gggaaaggga ctgggcctgt cccttcagta tttatagaca
     6661 tctctaccat tccattatga ttaaccgtaa tggtataaac atgggtattc tcatcccaat
     6721 tttctgtata agtataatga tttttatcgc cacttatatt tatctgaggt ttatgaccag
     6781 tatgcccttt taatgtaagt gttgttgtcc taaagtcatt atctacagga ttgatggaat
     6841 aatttttgct tatccagttc gctaactcta attcttcttt cttccaactt tttgatgcat
     6901 caaaatttcc tgataatgcc cacatagctg tcttatctgt cctgtaattg ttcaataaaa
     6961 tatgtaaatt atttggattt tctttaacaa cagcgtaagt atgtggcgtc aaatctaacg
     7021 ataacgactt tgtattatta gtatacatag gcaacattac ttgctgattt ttattgatat
     7081 tagcattact attataaata taccaggaat tacctacacg ctgagcatac ccatctcctt
     7141 cataaagttt tggataaagc gagtttaaat agttgacttt actagacaat tcctcactat
     7201 ttttagtcaa aatttttgca ttagggaata tagatgaaat cttttcctta tcaattttct
     7261 catgtattac aggaagaata tgatatctcc cattattata taaaggcatt gtttcatcat
     7321 tcgaataaag tccttgataa aatccgttta atgaactaat cctaccttct ccattccaaa
     7381 atacagcttt tgttctattt acaacttctt ccttacttgg agctggattt tgtatagcat
     7441 gtctaaagaa aggaataata cctttagtaa atgctggagt tggtacatca tttgtcataa
     7501 atgtatacgc ggcacattca aaattataaa ctgtgcctcc cccagtatat acattcatca
     7561 tttccatagc aatcattgat tctggttccg atgcatagga tctcatatcc ctagctcttc
     7621 cagtttcaaa tgtgtttgta taatgttttt cccaccattt ccatgtatct gttgatgagc
     7681 cccagttatc acataagcca ctcaaccaaa atccactaac gatagaatct gtacccgcat
     7741 catctcttat tggcgtattt ttagttgcca acaccaaatt tttatgatat ttttgactcg
     7801 cttcaaagaa tgtcggatca ttcataatag tttcccagaa ccatttttca tgatcatgcc
     7861 agataaaatg cgctccatat ttggcacaaa cttccaaata tttagcacta tgcggagcta
     7921 actggttatt gtaaatccaa taattctcaa tatttaaaac accttttaac acactatact
     7981 tttggaattg ttcatctaac cactctggag gaactgtatt acgctctcca gccgacataa
     8041 taaccaagaa aactggaatg tttagacttt gagcttcctc caacatcttg acataccatt
     8101 ctctcaattc tttcgtatct cgtggaatac aacttgttgg tttacagact tttgcaggat
     8161 gaagttcaat cgctgcatat ggttttacat cttcaggaat agcttcccat gctcccttca
     8221 atgtgttccc ccaccataat ccgttaccat tatcattgcc atacaacgga gaaagcaaca
     8281 atggcgattc attattaatc gtcgttctca tttgaacacg attatcagcc ttaactcctg
     8341 ctaacaatcc aaaacataac atcccaatac atacaaacag tattgtgatt aattttcttt
     8401 ttattttttc tttattcatg acttatacct aaaaatttaa ctcaataatt ttttctgaat
     8461 taaataccaa ttcaatattt tgtacatcag tatttttgcc atatattctt actcttactt
     8521 tttgatcttt gtttcctcct tccaatttta ggaatgttat atccccattt ttccaagcaa
     8581 acgatacctt atatcctcct cttactctga aacctttcac ttctccttct gaccaagcag
     8641 aaggtaaagc tggaattagt gataaccaat tatgatggct ctgtactaat aattcacaaa
     8701 ttccactcac caaacctaaa ttaccatcaa tttgaaatgg tggatggtca agaaataaat
     8761 tgccaagagt cgcattattt aacaaaccat taatctggtt ataagcaggt tcaccttgat
     8821 atagtctcgc aaaaaaatga atcagccatg cagcactcca acctgtttgt gtactagcat
     8881 gcaaaccact tactaaccaa ttattaatcg cttgctccct ctcctgtgaa gataaaaagt
     8941 tagcgtttga taatctccta ttgatagtga ttttagctgc ttctgctaat tccggagttt
     9001 tatgaatatc aatctcatta taaggataaa gcccaaatag aggtgaaatg tgtctatgcc
     9061 caggctctac ttcttcataa tcttctaacc attcttggat ttgcccatta ctacctattt
     9121 ttgttttagg tagtttcttt tttaactcct tcacacgact aataaaatcc gaattgtctc
     9181 ctaattgttt tgcaattcca atgcatgaat cacaaaaata tcttaaaatt tgattatcaa
     9241 ttgtagatga tagacaagca tttccttcaa taccattttt taagcgatat ttattttccg
     9301 gtgagacact tggacctgtc atcaagtagc catccacctc aaataaataa tcttcaaaga
     9361 aaagaaatgc ttcttttatc atttcaaaat gttccgtaag aatacgctca tcttggaaat
     9421 ataaatagtg ttcccaaata tgagtacata accatggaat agttaatacc caaattgcag
     9481 cccccatggc atgagattgg ggagccgtat cgccaaaacc atccgtatta tgatgtgctg
     9541 taaaacctct agctccatac attttcttag cggttagtct tcccggttct ctcattcttt
     9601 cgagcatatc aaataatgga tattctactt ctggtaaatc acatggacct accatccaat
     9661 aattcatttg agtattaata ttaatcgtat atttagaacc ccaaattgga tttaattcat
     9721 cacaccatat tccttgaaga ttggcaggta aaccattcgg ttgactagac gatattaaca
     9781 gatatcttcc ataatgaaat aacaagttag tcaagtagtt actatacttt ttagtgtttt
     9841 caagaagtag attcgttgga atgctaagac aacctttact atagtctagt ttaaaatcaa
     9901 ctctattaaa ttgctcctga tattttttta catgttcatc tttttctgta aagtaatcaa
     9961 tactactaaa ttctccctga agagaagaaa tatctatatt tccccaataa tccgtcattg
    10021 atttgagata aagaaatacc tctgtagcat tccgaataac tattgtctct cccaatacac
    10081 ttacttcacc atccgtaacc ttagaatgac atactacttt aaactgaaca ccttttctac
    10141 ctccagcaga ggccgacatt aaaattgtac ttgaatccag tttagatact tcgtcattaa
    10201 accgtttatt tctacccaaa ttaatgttta aatttaatgt gttttgaact gatgacacta
    10261 tacggcaaca taaaatattc ttattaaaac tcgtaaaata ttctcttttt atttgtaaat
    10321 tacaactatt aggctcaaac acaacattag aaatagctgt atctaaatct agctctcttt
    10381 catacaatga aagagcacaa gactgaatat ctatatgctc aatgtaaagt tccccaagta
    10441 attcatagtg gctttgatct cttggggtag caaacattgt taactttatc aattcttcgg
    10501 ctttctgaat ttctccatct aaaagatatt cccgaatttt tttaagatgc aatagtgagt
    10561 ctggattatt tctatctgac tttcctctat accaaatagt ctcatcgttt agttgaatac
    10621 attcttttgt agctgaacca taaatcatac cacctaaatg accgttccca atcggcaagg
    10681 cttcattcca atttgcggca gctttcttat accataattt cactctttac ctctcttcca
    10741 aaatggaggt gatatcccaa ataccacctc cacactttct actacttcaa aattcctaaa
    10801 acaactagga taactccaat agccataaca ctaaagatta gtacaaccgg attctttcct
    10861 tttctaatta atttacacat taataaagtc aaagccatag ggataaatcc tggaattaat
    10921 tttgtaatca tttcttgaac agaaataaca agttccccct gcttaaattc taatccaaaa
    10981 ttaataccaa ccattgatgg aatcaaacca cccactagta ctagccctaa tgctgtcgcc
    11041 atactcgtaa cgcgattcaa tgttcctttt gtattatttt cttggataag actagaaccc
    11101 ttagtatacc catatttcaa accgaaatat ttaacaggaa tattaataat attaaacaat
    11161 attaaggcga taaagatacc taaagcaccg ccgtctttag aataagacgc accaatacta
    11221 aaacagatag gaactagtgt cagccagaac aaactatctc ctagaccagc cagtggcccc
    11281 atcaagccaa ctttaatacc agtaattgaa gctgcacctt catttccttc ttgttcttcc
    11341 atagcggaag taactccaag aataaatggt gccgctgttt gatgagtatt gaaaaactca
    11401 aggtgacgtt tcattgcagg agaagctgaa tctttgtctg ggtatagttt tttcaatact
    11461 ggaagaattg tatatagaaa acctaggttc tgcattctct catagttcca tgaagaacca
    11521 tacataaaac ttcgtttgaa aactttttta agttcaactt tagttacttt attattcatc
    11581 atagatcaag atcctcctca acatcactac ttgaagttgt ttcttgtggt ttacttccaa
    11641 tcatatcgta gaagtatgct accgcaatac caactagtga gatcccaatg gttgacattc
    11701 ctccatacac agaacaaatg aatccaatca acaagaatac ccacatattt ttcttgagca
    11761 tcatatttaa aagcatacca aaaccaattg aaggtagtaa agcacctgca gagttaagtc
    11821 cctgcataac gattggtgga accttagcaa acaagtctgc cacatattcc cctccaagca
    11881 taatagctag gaaaattggt acaattttaa ataacgtgat taaaaccaaa cttgaataat
    11941 gataaaaacc gatctttgaa taatctccgt ttttagcatc attatcagct tttttcacaa
    12001 aataaacatc taaagttttt gcaagaacat ccaactgttg ggtagcaact gcaattggaa
    12061 ctgctatagc gataccagca gtttctcctt gaccagataa aataccaaat gcagtaccaa
    12121 taatcgcacc tgaaatagta tctggtggag tgtaacctcc aatacctgtt acaccgagcc
    12181 aagttaattc aagagctgaa ccaataagaa caccttgggt gaaatctcct aagactaagc
    12241 caaccattgc acttgtaact aagggacggt gaatcataaa taacggtcca ttatagtcaa
    12301 tagtggcaat aatcccaact aatgtcacca gtaatgcttg tgtgaatagc atatactgta
    12361 cctccttaaa ttatttttat aaaaattttt ccaacattgt aactttatca ttaggaacca
    12421 tttgaatttc aactctcgtt cccttatcaa ctattttctt aaaataatat ttgtcttctt
    12481 cacctagagc tacacctccc gttacctttt cattttcctc cgttttactc atctgtccta
    12541 cattgaggta ctccaatttt aaatttcctt caatagaatc atacacatct tttggatttg
    12601 tatatatcag cattgttctc ttttttattg gcacagagtt taaaacttcc acaaaccgtt
    12661 ttacactaaa gaaaacaatt tttaaaccta ccggtgcaga aatctttaaa atagattgtc
    12721 gtgttttatc ttctgagatg cgatcattaa caatgataac ttgctcaata tcatactttt
    12781 ttagccacgt agtgacaact tgaccatgta ccagacggtc atcaatacga acaaactcta
    12841 tagacataaa tcctcttcct cctctacgtt aagttgttgt ttaacattaa acaaactatt
    12901 ttgagcattt tgaacaattt cttctaaatt gatttttgaa tcataacttg atattaattc
    12961 cactaggaga gggatattaa accctgttac aatatcaact gaatccaaat ttaaaaaccg
    13021 tgacaaagcc acattattag gacttcctcc aatcaagtca gtcaaaacga taacctcttg
    13081 atttgagtct aacagttcat ttacttgatt tttaaaataa tgttcaaact ctacaatatt
    13141 ctctccaggc atcaaaccta atgtcctaac tctatcattt gttgtctcac caacaaacat
    13201 ttctgcggtc atgagagctc cgctagcaaa attaccatga ctggcaacta aaattcctct
    13261 attaaacatt ttctctttca acaactactc ctttcttaag gataatatta gcataaagtg
    13321 aagtttctcc tgtagcaaca atagcataag ctttcttact acgttcataa aagtcttctc
    13381 ttctaagata agtaatcgtt ttaagatctg taccatgacc ttcaatcatc tgtctatagg
    13441 taccccatat cttaggaata tcatcacccg aaacaacgtt cataaactga attgaactat
    13501 cgacgtaact atctaatggc attaaataca gaatggaatc taataattct ggaatattta
    13561 caccatcaca acgaattagc ttatttgcac atgaggcaga aggataattc gcgtcagcta
    13621 atactatttc atctccatgt cccatttcca ttaaagtctt caataaatct ggagaaatat
    13681 ttttcggtat atgttttaac attaatatcc tccctatttt ctctgaccgt atgttttaaa
    13741 tttttctgcc atcaattcca tctcctcatc aggaagaact actggctctc caaaattctt
    13801 agctaaacaa taaatttttg cacaatattc aacttcttca acaatattaa atgcattcaa
    13861 taaattttgt gcacctgcta aaattccatg attcgctagt aaaactgctc tacgaccttc
    13921 cattgcttta gctgcattca cagccaattc tttcgtgcca tatgttgcat actcagctac
    13981 ccgaacatct ttccctgcca ctgcaatcat ataatgactc gctggaagtg gttctctgag
    14041 acaagctaat actgttgcat aagttgtatg agcatggata attgcatcga tatcatcacg
    14101 agtttgatat tgaatcaaat gcatatacca ttcgctagat ggcaagcgtt ctccctctac
    14161 aacatttcca ttaatatcca tcactacaat atcggattct ttgatttcaa agaaatcaat
    14221 acccgacggg gtaattgcca tcaattgttt ttcacgatcg aaaacgctga gattcccacc
    14281 tgttcctttc gtcaaatctg tttctactag cttcttacca tatttaatta attcttgttt
    14341 tacatctgac atccttgtcc tcctcatatc aaaacactaa atatttttca attcaccaat
    14401 tatcccccct tcctgcacaa aagctaagaa gggggaggga ggcaaattta caaactctca
    14461 atctttttaa ttcttttggg agtaataact ctctaattgt agaaactcct caataacatg
    14521 gtgagcctct tccatccctt ttaattgtcc catagctatg agctgcacaa caatattccc
    14581 cacagctgta gcctcagtca aacctgtaag aacctcttta ccagttctat cagcaatcat
    14641 ttggttaaag taactggctc tagcacctcc tccaatcaca tatatcctct tataaacctt
    14701 atgagttagt tcttctagta actctatcgc tttcctatac gtttcagcta ggctttcata
    14761 aacaatctta aatagttgtc catctgtcca ctctctagtt tcatgatgat aagctagata
    14821 ttctgtcaaa gtcttgtgca tatcagattc tgttgcaaat tcagttgatt cagtatcaat
    14881 cagaggaaga ttttcttttt ctttctccac cattgtccta atatcatcaa aagaataggc
    14941 tttccctctt cgttcaaatg aacgtcttag ttcctctatg atccacaacc ctgtacaatt
    15001 cttcagaaat gtaatcactc catctttacc gacttcattt gtaaatccat aactgaagga
    15061 ttcggtagta agaagcggtg aagtaagttc cactccaacc aaagaccaag tacctgatga
    15121 aataaataaa ctaccttctg tcttaggtac tgagacaatc gcgcttgctg tatcatgact
    15181 acaaacattc acaacaggaa tatcgcctaa accatactcc ttttttatcc ttccaagaac
    15241 atttccctct gaaacaatct caggaagtaa agatgaatcc aattcaaata gttttaagat
    15301 attctgattc cagttttgac tcctaggatc aaataattga gttgttgaag caatgctttt
    15361 ttctgtagca aacttacctg tcaagagata attaaacaaa tctggcatta aaagaatctt
    15421 attggtctta tagaaagagt caggagattc ttgacgtgcc ttaaagagtt gaaacaaggt
    15481 atttatctcc ataatctgat ttcctgtctc tgaatacagt ttttctaatt cagtcatttc
    15541 agatatttcc tttaacactc cctttgttct ttcatcacga taatgaacag gttgtaataa
    15601 cagcttacct tcattatcaa tcagtccaaa atcaactccc catgtgtcaa taccgataga
    15661 taaaatcttg taactagtat tagccaagcg gatactttca agaattttag ctagtagaaa
    15721 gtcaatatcc caagataaat gcccttttac tctaataggt agattagaaa agcgatttat
    15781 ttcttccatt actagtttat tttcagaaag gtaaccaacg attgctcttc cagaagtcgc
    15841 acctaaatct attgctaaaa ccgcttccat ttttcttctc tcttcgtcct tgattaactt
    15901 tattataatc cccacgtttt attttttcaa tatgtgaacg cttacttgaa taatgttcaa
    15961 atgttaaccc aatattcata aaaataattc aaattcctcc aatttgtgct ataatatagt
    16021 tgaaatgata aattaggagg agcttatgat aaaagatgaa cgtgtacttg aattgattga
    16081 aattattaaa aagaaaaaaa gaattgccgt aaaagagctg gcagaaatca ctttctccag
    16141 cacaagtacc ttacgtcgtg atttaatttt cttagaaaat caaggtctta tcaaaagaaa
    16201 gcacggatac gtgaccctgt cctctatgaa cacaattgaa ctttctcatc aaatacggga
    16261 aggagaaagt actaggcaaa aaagactaat cgctagtctc gctaaagact ttattcggtc
    16321 tggtatgtgt gtttatctgg attccagtac tactgtctac gaactttgtc cctatctttc
    16381 tgaacttgat aatttgatta tttttacaaa tggtttacat actgcacaaa ccctatctga
    16441 aactgttaaa gatagctcca aaatctttat cacatctggc gaggtcaaac atcaatcctg
    16501 ttccgtggtc aactatgata aggaaaattc tttattagat cattttaata tcgatttagc
    16561 attttgttca gcaagaggta ttgatgacca atatgtttat gaagcttctc tcagccaagc
    16621 tatttcaaaa aagaatatta ttgacaaagc ccatgaaacc atcttactga ttgatagttc
    16681 taaattttac aagactggat tttttaaaat taatcccctc tccaaataca caacctttat
    16741 ttcagacacc gtgccagatc aaaaattatt agacgcagtc gaattatttg atggagaatg
    16801 ggtttctgat attcaatgaa aatcaaatag gaagctagtc tcagcttgct caaagtacag
    16861 atttgaaaac tgatgaagtc agctcgaaac actgttttga ggttgtagat agaactgatg
    16921 aagtcagtca catatatacg gaaagacgaa gctgacatga tgtgaagaga ttttcgaaga
    16981 gtattcgttc tgtctgctga ctgatttaca aatattcacc acatgacatt attttctcag
    17041 caaccctaaa aacagaggct ggacaaaaac tcaatttcag gagaaaatgg agtaaacctt
    17101 cccacaataa aacgcatagt atcaagtttt tgcacacctg atattatgcg tttttctgat
    17161 tttaaagact ttgtcgccta gaccctatat ttcaagaatt aagtgacctt gatgatctaa
    17221 atgtattgtg gtatacta
//
LOCUS       DAVBOM010000047        16933 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBOM010000047 DAVBOM010000000
VERSION     DAVBOM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.047"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..211
                     /locus_tag="VQ878_001654"
     CDS             <1..211
                     /locus_tag="VQ878_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3095963.1"
                     /translation="PRKSSKLKPLIAEDKAYNHALSKDRSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLSAGIINHELGF"
     gene            260..724
                     /locus_tag="VQ878_001655"
     CDS             260..724
                     /locus_tag="VQ878_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET3095964.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            882..1307
                     /gene="lacA"
                     /locus_tag="VQ878_001656"
     CDS             882..1307
                     /gene="lacA"
                     /locus_tag="VQ878_001656"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET3095965.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1338..1853
                     /gene="lacB"
                     /locus_tag="VQ878_001657"
     CDS             1338..1853
                     /gene="lacB"
                     /locus_tag="VQ878_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET3095966.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1864..2793
                     /locus_tag="VQ878_001658"
     CDS             1864..2793
                     /locus_tag="VQ878_001658"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET3095967.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQAVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2795..3775
                     /gene="lacD"
                     /locus_tag="VQ878_001659"
     CDS             2795..3775
                     /gene="lacD"
                     /locus_tag="VQ878_001659"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET3095968.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4009..4845
                     /locus_tag="VQ878_001660"
     CDS             4009..4845
                     /locus_tag="VQ878_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3095969.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4881..5198
                     /locus_tag="VQ878_001661"
     CDS             4881..5198
                     /locus_tag="VQ878_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3095970.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5198..6889
                     /locus_tag="VQ878_001662"
     CDS             5198..6889
                     /locus_tag="VQ878_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3095971.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7104..8510
                     /gene="lacG"
                     /locus_tag="VQ878_001663"
     CDS             7104..8510
                     /gene="lacG"
                     /locus_tag="VQ878_001663"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3095972.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIIRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8600..8812
                     /locus_tag="VQ878_001664"
     CDS             8600..8812
                     /locus_tag="VQ878_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET3095973.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(9091..9852)
                     /locus_tag="VQ878_001665"
     CDS             complement(9091..9852)
                     /locus_tag="VQ878_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3095974.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10034..10996)
                     /gene="nrdF"
                     /locus_tag="VQ878_001666"
     CDS             complement(10034..10996)
                     /gene="nrdF"
                     /locus_tag="VQ878_001666"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET3095975.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11184..13343)
                     /gene="nrdE"
                     /locus_tag="VQ878_001667"
     CDS             complement(11184..13343)
                     /gene="nrdE"
                     /locus_tag="VQ878_001667"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET3095976.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13424..13642)
                     /gene="nrdH"
                     /locus_tag="VQ878_001668"
     CDS             complement(13424..13642)
                     /gene="nrdH"
                     /locus_tag="VQ878_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET3095977.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13993..14256
                     /locus_tag="VQ878_001669"
     CDS             13993..14256
                     /locus_tag="VQ878_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET3095978.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14262..15995
                     /gene="ptsP"
                     /locus_tag="VQ878_001670"
     CDS             14262..15995
                     /gene="ptsP"
                     /locus_tag="VQ878_001670"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET3095979.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16250..>16933
                     /gene="phtA"
                     /locus_tag="VQ878_001671"
     CDS             16250..>16933
                     /gene="phtA"
                     /locus_tag="VQ878_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3095980.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT         5282 a         3057 c         3509 g         5085 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccgct aatagctgaa gataaagcct ataaccatgc
       61 gctatctaag gatagaagca aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgagtgc
      181 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata aagaaactag
      241 caaggtcagg ccttacttta ttggtggaca tccaggattt aattgtcttc tacttgatga
      301 tgaagtctat gaagattatt atctagagtt tgagaaagaa gagatttgct ctgttccacg
      361 tcctttccca gaaacaggta tgttggattt ccaagataga agtccatggc tagagggaca
      421 aaaagaaata gatcttagtt atgatctttt cagcacagat gcagtgactt tggatgaatt
      481 gcaatctcga acaattgccc ttcgttctct taaacatgat aagggattga aagtgcattt
      541 tgcagaattt ccaaacctca tcatctggtc aactttgaac aagggacctt tcattacctt
      601 tgaaccatgg tctggcttgt caacattcct tgaagaagga gatcatttag aagataagaa
      661 gaatgtttgt ctcttagaag ccaatcaggt tgaagaatta gggtttgaga tagaagtttt
      721 ataaaaaaag taaaaaataa ataacaaaaa caaacacaaa ctgttgactt cttcaaacaa
      781 tagtagtata ttatgtttgt gaggactaat tgactgtttt ttaaagacag ccaatacact
      841 gctggaatcc agcatagaaa aaataaaaag gagtatacaa tatgtctatt gttatcggtg
      901 cagatgctgc aggtttgaga ttgaaagaag ttgtgaaaga cttcttagaa aaagaaaact
      961 tccaccttgt ggatgttaca gctgaaggtc aagactttgt tgatgtgact ctcgctgttg
     1021 ctgcagaagt aaacaaagaa gaacaaaacc ttggtatcgt gattgatgct tatggagctg
     1081 gtccatttat ggttgcaact aagatcaaag gaatggttgc tgcagaagta tctgacgaac
     1141 gttcagctta tatgactcgt ggccacaaca actcacgtat gatcactatg ggggcacaac
     1201 ttgttggtga tgaattggct aaaaacatcg ctaaaggatt tgttaatggt aaatacgacg
     1261 gtggtcgtca ccaaatccgg gttgacatgt tgaacaaaat gtgctaatta gattatagta
     1321 agaaaggtaa gttaaaaatg agaattgcaa ttggatgtga ccacatcgta acagatgaaa
     1381 aaatggcggt ttcagaattt ttgaaatcaa aaggatatga agtcattgac tttggtacct
     1441 atgaccatac acgtactcac tacccaatct ttggtaaaaa agtaggggaa gcagtaacta
     1501 gtggtcaagc tgatctcggg gtatgtatct gtggtactgg tgttggtatc aacaacgctg
     1561 taaataaagt tccaggtgtt cgttctgcct tggttcgtga tatgacaaca gccctttatg
     1621 ctaaagaaca attgaacgcc aacgttatcg gttttggtgg taagattact ggtgaattgc
     1681 ttatgtgtga tatcatcgaa gctttcattc atgctgaata caaaccatct gaagaaaaca
     1741 aaaaattgat tgcgaaaatt gaacaccttg aaagtcacaa tgctcaacaa acagacgcaa
     1801 acttcttcac tgaattcctt gaaaaatggg atcgtggaga ataccacgac taagaggtaa
     1861 cctatgattt taacagttac aatgaaccca tccattgata tttcctatcc cttggatgag
     1921 ttgaagattg atactgtcaa tcgtgtggtg gatgtaacca aaacggctgg tggtaaggga
     1981 ctcaatgtta cccgagtact ttcagaattt ggcgattctg ttcttgctac tggtttagtg
     2041 ggtggcaaac ttggtgagtt tttggttgaa catatcgata atcaagtaaa gaaagatttc
     2101 ttctcaattc agggagaaac tcgtaactgt atcgctattc tccacggaga caaccaaaca
     2161 gaagttcttg aaaaaggtcc tgaagtattg gaacaggaag gtcaagactt tttggaacat
     2221 ttcaaaaaac tcttggagtc agttgaagta gtggccatct caggtagtct gccagctggc
     2281 cttccagttg attactgtgc gagcttggta gaacttgcta atcaagctgg caagcctgta
     2341 gtcttggact gctcaggtgc agcacttcag gctgttcttg aatcacccca taaaccaaca
     2401 gtcatcaaac caaataatga agaattgtct cagcttcttg gaagagaagt ttctgaggat
     2461 ttggatgaat taaaagaagt acttcaagaa cctttgtttg cagggattga atggattatc
     2521 gtttcacttg gtgccaacgg tacttttacc aaacatggtg acactttcta caaggtagat
     2581 attcctagaa ttcaggcggt aaatcctgtt ggatctggag actctactgt ggcaggaatt
     2641 tcttcaggac ttcttcacaa agaatcggat gcagaattac tcatcaaggc aaatgtcctt
     2701 ggtatgctca atgctcaaga aaaaatgact ggtcatgtca acatggccaa ctatcaagct
     2761 ctatatgatc aattaatagt aaaagaggta taaaatggct ttaacagaac aaaaacgtgt
     2821 acgcttagaa aaactttctg atgaaaatgg tatcatctca gctcttgcat ttgaccaacg
     2881 tggtgctttg aaacgcctca tggctcaaca ccaaacagaa gaaccaactg tggcccaaat
     2941 ggaagaactt aaagttttgg tagcagatga attgactaaa tacgcttcat ctatgcttct
     3001 tgaccctgag tatggacttc cagcaactaa agctcttgat gaaaaagctg gtcttctcct
     3061 tgcttatgaa aaaacaggtt atgacacaac aagcacaaaa cgcttgccag actgcttgga
     3121 tgtttggtct gcaaaacgta ttaaagaaga aggtgcagat gcagttaaat tcttgcttta
     3181 ctatgatgta gatagctcag acgaactcaa tcaagaaaaa caagcctaca tcgaacgcat
     3241 cggttctgag tgtgtggctg aagatatccc attcttcctt gaaatccttg cttacgatga
     3301 aaaaattgca gacgcaggtt ctgtagaata cgctaaagta aaaccacaca aagttatcgg
     3361 tgctatgaaa gtcttttcag acccacgctt taacattgat gtcttgaaag ttgaagttcc
     3421 tgttaacatt aaatatgttg aaggcttcgc tgagggtgaa gtggtttaca cacgtgaaga
     3481 agcagcagcc ttcttcaaag cgcaagatga agcaacgaac ttgccataca tctacttgag
     3541 tgctggtgta tcagctaaac tcttccaaga tactcttgta tttgctcatg aatcaggtgc
     3601 aaactttaac ggagttcttt gtggccgtgc tacatgggca gggtcagttg aagcttacat
     3661 caaagatggt gaagcagcag ctcgcgaatg gcttcgcaca actggatttg aaaacattga
     3721 tgagctcaat aaagttcttc aaacaacagc gacttcatgg aaagaacgtg tgtaagaaag
     3781 tcctcctagt ttaggaacat gaatctaaaa aaatttaaaa aaagttgtat gtaaaggttt
     3841 acaaaataac ttacttgtgc tatacttaaa tcacaagtta atacaaggtg agtgttacta
     3901 agtaatatta ggcatgatca caggtgaatt agaaatcagc tgattttcta gttcatttgt
     3961 ggtcattttt tgtactcata tacctttaaa atataaaagg aggttgacat gtatcgaatt
     4021 ctaaatccaa tgaatcacaa tgtctcgctt gtcagaaatg ataagggaga agaggtgatt
     4081 gtaattggta aggggattgc attcggaaag aagaaggggg atttgattgc tgaaaatcag
     4141 gttgagaaaa tctttcggat gaagaccgaa gagtccagag aaaactttat ggctcttctc
     4201 aaagatgttc cgcttgattt tatcacagtg acctatgaaa ttattgataa gctatcaaag
     4261 aaatatcatt atccgattca agagtatctc tatgtaacct tgacagatca tatttactgt
     4321 tcttatcaag ctctaactca aggaaggtac aaggatagta atctgccaga tatttccgct
     4381 aagtatcctg tcgcttttca aatcgcaaat gaagcttttg aaatttaccg tcagaagcta
     4441 gcagatcatt ttcctgagga cgaaattatt cggattgctt atcatttcat taatgctgaa
     4501 ggtgaaaatg aagtggaact tgtggagtcg attgataaga ggaaagaaat tctcaggaat
     4561 gttgaagaag ttttaacgga ctatgcaatt caacgaacta aaaagaataa ccatttctat
     4621 gatcgcttta tgatccattt gaattatttc ttggattatt tagacagatc tagagatgat
     4681 aaccaatcac ttctggatat ggaagatcat attaaacaat cctatccaaa agccttcgag
     4741 attggttcca agatctatga tgtgattacg caacatacgg gtcttgattt gtataaaagt
     4801 gaacgagttt atctagttct acatatccaa cgtttattgt cataaaaatt tatttaaaac
     4861 tatataagga gaattctatc atgaatagag aagaagtaac attgttaggt tttgaaatcg
     4921 tagcctatgc tggcgatgct cgttcaaaac tattggaagc cttgaaggct gctgaagctg
     4981 gtgattttga aaaagcggac gctctggtag aggaagctgg tagctgtatt gcagaggctc
     5041 accacgcgca aacaagtcta ttgactaagg aagcttctgg tgaggactta gcgtatagtg
     5101 tgaccatgat gcatggtcaa gatcacttga tgacaactat cttgttaaaa gacctaatgc
     5161 accatttaat tgaactttac aagagaggag ttaaataatg aataaactaa ttgcatttat
     5221 cgagaaagga aagcctttct ttgaaaaact atctcgtaat atctatcttc gtgctattcg
     5281 tgatggtttc attgcaggta tgcctgttat tctcttctca agtatcttta tcttgattgc
     5341 ctttgtacca aactcatggg gctttaaatg gtctgatgaa gttgtagcct ttctgatgaa
     5401 accttatagc tattctatgg gtattctggc tctcttggta gctggtacaa cagctaagtc
     5461 attgactgac tcagtaaacc ggagcatgga aaaaaccaat caaatcaact atatgtcaac
     5521 attgttggca gcaattgttg gtttgttgat gttggcagct gatcctatcg aaagtggtct
     5581 agctactgga ttcttgggaa caaaaggttt gctttcagcc ttccttgctg ccttcgttac
     5641 tgtagccatc tataaggtct gtgttaagaa caacgtcact attcgtatgc ctgacgaagt
     5701 tccaccaaat atctcacaag tctttaaaga tgtgattcca ttcactctat cagtggtttc
     5761 tctttatgct cttgatttac tagctcgtca ttttgttggt tctagtgtgg cagaatcaat
     5821 cggtaaattc ttcgcaccac tcttctcagc agcagacgga taccttggta ttaccattat
     5881 ctttggtgcc tttgccttct tctggtttgt tgggattcat ggtccatcta tcgttgaacc
     5941 tgctatcgca gcgattacct atgcaaatgc tgaagtcaac ttgaaccttc tccaacaagg
     6001 gatgcatgca gacaagattc ttacttctgg tacacaaatg tttatcgtta ccatgggtgg
     6061 tacaggtgcg acattggtcg ttccatttat gttcatgtgg ttgacaaaat cgaaacgtaa
     6121 ccgtgcaatc ggacgtgctt cagtagttcc taccttcttc ggtgtaaatg aaccaatctt
     6181 gtttggtgca cctcttgttt tgaatccaat cttcttcatt ccatttatct ttgctccaat
     6241 tgcaaacgta tggattttca aattctttat tgaaactctt ggaatgaact cattcactgc
     6301 taatctacca tggacaactc cagctccact aggtctagtt cttggaacta acttccaagt
     6361 gctatcattc attcttgctg cccttctaat tgtggttgac gtagttattt attacccatt
     6421 ccttaaagtc tatgatgaac aaattcttga agaagaacgt tcaggtaagt ctaatgatga
     6481 attgaaagaa aaagttgctg caaacttcaa cactgcaaaa gcggatgcta ttcttgaaaa
     6541 agcgggtgtc gatgcagcac aaaataccat cactgaagaa acaaatgtcc tcgttctctg
     6601 tgctggtgga ggtacaagtg gactccttgc aaatgctttg aataaggcag cagcagaata
     6661 caatgtccct gtgaaagcag cagcaggcgg ctatggtgct caccgtgaaa tgttgccaga
     6721 gtttgatttg gttatccttg ctcctcaagt tgcttcaaac tttgaagata tgaaggcaga
     6781 aacagataag ctcggtatta aacttgctaa gacagaaggc gctcaataca tcaaattaac
     6841 tcgtgatgga aaaggtgccc tagcattcgt acaagagcaa ttcgattaag gctaggaact
     6901 gtgaaacagt ctcccatcgt tacggaaatc gctatggcga atttcctaat cgccttatta
     6961 attcgtcggt aaaaagatat cgtttttacc tcctcatgtc acaattcagt gacttggtac
     7021 aagaagtgag atggagaagc atggctcact gactcctctc ctctcacttt tactttattt
     7081 aaatcaagaa ataggtgaaa aaaatgacaa aaacacttcc aaaagacttt attttcggtg
     7141 gcgcaacagc tgcttatcaa gcagaaggtg ctacacatac tgatggaaaa ggaccagttg
     7201 cttgggataa atatcttgag gataactact ggtacactgc cgaaccagct agtgattttt
     7261 acaatcgata tccagttgac ctcaagctag cagaagagta tggtgtcaat ggtattcgaa
     7321 tttctattgc ctggtcacgt attttcccga ctggttacgg ccaagtaaat gttaaaggtg
     7381 ttgagtttta tcataattta tttgcagagt gtcacaaacg tcatgttgag ccctttgtaa
     7441 ctcttcatca ctttgacacg ccagaagctc tccattcaaa tggagacttc ttaaaccgtg
     7501 aaaatatcga acattttgta gactacgctg ccttctgttt tgaagaattt ccagaagtaa
     7561 actattggac aacctttaat gaaattggac caatcggtga tggtcaatat ttggttggga
     7621 aattccctcc aggtatccag tacgaccttg ccaaagtctt tcaatcacac cacaatatga
     7681 tggtgtctca tgcgcgtgca gtcaagctat ataaagataa aggctataaa ggggaaattg
     7741 gtgttgttca cgctctgcca accaagtatc ctttggatcc taaaaatcca gcagatgttc
     7801 gtgcagctga gttggaagat atcatccaca ataaattcat cttagacgca acttatctag
     7861 gtcgctattc agctgaaacc atggaaggtg tcaaccatat cttatcagtc aatggtggta
     7921 gtttggatct tcgtgaagaa gattttacaa cattagaagc tgcaaaagac ttgaatgatt
     7981 tcctaggaat caactactat atgagtgact ggatggaagc ctttgatgga gaaactgaaa
     8041 ttatccataa tggtaaaggt gaaaaaggaa gctctaagta tcaaatcaaa ggtgttggtc
     8101 gtcgtgtagc tcctgactat gtaccacgca cggattggga ttggattatc taccctcaag
     8161 gtttgtatga ccaaatcata cgtgtgaaga aagattatcc taactacaag aagatttaca
     8221 tcactgaaaa tggtctcggc tataaagatg agttcgttga taacactgtt tacgatgatg
     8281 gtcgtattga ttacgtgaaa caacacttgg agatcttgtc tgatgcgatt gcagatggag
     8341 ctaatgtaaa aggttacttc atttggtcat taatggatgt cttctcatgg tcaaacggtt
     8401 atgaaaaacg ttacggtctc ttctacgtag attttgaaac tcaagaacgt tatcctaaga
     8461 aatcagctca ctggtataag aaagtagcgg aaactcagat tatagactag tagaattagt
     8521 cattagatat agaattttag tgagtcaaaa agatgttcaa agattttatc caatctattt
     8581 atgaaaaaaa gtttatatta taaatttcga aaaatgctct caaataccgt gtttgacgag
     8641 tgaagaattg aaaagtcttg gaaaatggta tgtctcgact ggtaaagaat ggatttgtca
     8701 ttcagatgat gagctggaag aatttaaaaa tctattttta aattttatca atcctgaaga
     8761 atgggatact atctcctttg attcagattt tatgccgttt caacaatcgt aaccaatttc
     8821 tcaaaaaagt taaatcttat atttagtact ctgtaaaact cttatctaat cacgttgctt
     8881 atactcaatg aaaatcaaag agcaacttta aactaggaag cgagtcgcag atttctcaat
     8941 gcatagcttt gaggaattgg gcaaaaagtc tttgatatag aaaaacgcat agtatcaggt
     9001 gtttcaacac ctgatattat gcgttttatt gtgggaagat ttactttttt tcttctgaaa
     9061 ttgagttgtt acccaggctc tttcagttta ttaaggcttg atgactttaa tgtgtttaga
     9121 tagcttaaaa aggattgaat cacttagttt agaatctgaa acaatagtat caagatttga
     9181 tacattataa aaagtataaa aatcaaactt attgaacttg ctatgatctg cgagtaaata
     9241 ttttttatta gaattattta aagcgatgcg ttgagcctct ccctcttcct cgctaaaagt
     9301 agctagagct ccgttttgaa taccattaca gctaacgaaa gctttagaaa attggagatt
     9361 agagagattt tgtagggtca atgtaccaac aaaagcacct gtaatatcgc gataatttcc
     9421 acctattaaa atcaaatctg ttaattttcg ttcgcttaaa atcagaaaaa caggtagact
     9481 gttggttacg acgcggatat tgtcaatagg caactcacgc gcaaaaaact ctaatgttgt
     9541 tcctggtcca atgaaaatag tttctctttc ttctactaga ctgcctgcaa aatgggctat
     9601 ttcttgtttt tctgccgttt ggagggcttg tttttcaata tttgatcgct cattagtcaa
     9661 aagggagttg gttcgaagtt tttcagctcc accatgcaca cgaatcagca aatctttatc
     9721 agctaattcc tgtaaatagc gccttgcagt catatctgaa acggctattt cgtccataat
     9781 ctgtttaact gttatggttc ctttactatt tactatctct aaaattttgg ttaatttttc
     9841 ttgtttgagc atattatcac ctcgtttcct actactatct taccataaac aaactcatca
     9901 ttcaaataca aaaacaacaa aatgaaacaa aaacaaaaat atcgaagttt gttttcaaaa
     9961 ctttcgatat ttttgttggg ttataacttt gatgtttcta gtttactttt tgatgattga
    10021 gagtgatgga gaattagtct aaaccgtagt tatagtcatc gtcttgcatg gcttcaactt
    10081 cgccaagaag gtaaccattt ccgacttgag agaagaagtc atggttggaa gttcctgttg
    10141 aaataccgtt cataacgatt gggttgacat cttcagctga atctgggaaa agtggatctt
    10201 gtcccatgtt catgagagct ttattggcat tgtagcgaag gaaggtttta acctcttcag
    10261 tccaaccaac accgtcataa agactctctg tgtagccttc ttcattttca taaagagtat
    10321 agagtaggtc gtacatccat tctttgagtt tttcttgctc ttcttcaggc aattcattga
    10381 aaccaagttg gaatttgtaa ccaatgtagg ttccgtgaac agactcgtca cgaataatca
    10441 atttaatgat ttctgcaacg ttggctagtt tgttgttacc gagatagtag aggggagtga
    10501 agaaaccaga gtagaagagg aaggtttcga ggaagacgct ggcaactttc ttttcaagtg
    10561 ggctgccgtt taggtagatt tcgttgacaa tctcagcctt cttttgtagg taaggattgg
    10621 tattggtcca ttcgaaaatt tcttcaatct cagccttagt attcaaggta gaaaagattg
    10681 atgagtaaga tttagcgtgg acagattcca taaattggat gttattgaaa acagcttcct
    10741 catgtggtgt acggatgtct gcgcgaaggg cttgaacccc agtttcagat tgcatagtgt
    10801 caagaagggt taaaccacca aaaacttttc cgaccaagtc tttctctttg ttagatagct
    10861 ttctccagtc atccaagtcg tttgataagg gaatacgtgt atcgagccaa aattgctccg
    10921 tcagtttttc ccaagttgat ttgtcgatga catcttcgat ggcattccag ttaatggctt
    10981 tgtagtaagt ttccatttaa aatctctttc tgtgtttagt attgcgaact cacaattatt
    11041 tctactttac cataattcta taggagtatc gcacaaaaag tcggaagccc gacttttaaa
    11101 atgttacata aattatgtta tgacatagta gatttgattt tatcagtgct gcttagggaa
    11161 aaataatgtt tctatgctag aaactaaatc acacagcttt cacattggtt ggcgccgact
    11221 tctccaccgt catctgtaaa ggtacggacg tagtagatag acttgattcc cttgttaaag
    11281 gcatagttac gaaggatgga caaatcacgt gtcgtttgtt tattttccct cttccattcg
    11341 taaaggcctt ttggaatgtc actgcgcatg aagagggtga gtgaaagtcc ttgatccacg
    11401 tgttcagtcg cagcagcgta aacatcgatg actttacgca tatccatatc gtaggcagaa
    11461 gtgtagtaag gaatggtttc tgtagacaag ccagcagcag ggtagtagat tttaccaatt
    11521 ttcttctctt ggcgttcttc gatacgttgc gtaatcgggt ggatagaagc agaaacgtcg
    11581 ttgatatagc tgatagaacc atttggcgct acagcaaggc gattttggtg gtaaagacca
    11641 tcttcttgaa ccttgtcgcg aagttcagcc caatcagcaa caccagggat aaaaacattt
    11701 ttgaagagtt ctttaacacg gtctgatgtt ggaacaaatt caccagttac atacttgtca
    11761 aagtaacttc cgttagcata gtctgatttt tcaaagttgt ggaaggtaat accacgttca
    11821 cgcgcaatat tgtttgactc taccaaggtc cagtagttca taagcataaa gtagatgctt
    11881 gtaaattcaa cagactcagg tgaaccatat tcaatgagtt gttgggcaag gtagctgtgc
    11941 agtcccatgg caccgagacc aaaggtgtgg gcttggctat ttccatggtc aatcgttggt
    12001 acagctacga tatgtgaact atctgtaacg aaagtaaggg cacgaaccat agcacggata
    12061 gaacgaccaa aatcaggtga agtcatcatg ttaaccacgt tggttgaacc cagattacat
    12121 gaaacatctg ttcccatttg aaggaattct tgagcatcgt tgatcaagct tggttcttga
    12181 acttgaagaa tctcagaaca caagttactc atgataatct ttccatcaac aggatttgca
    12241 cggttagccg tatcgatgtt gactacataa ggatagccag actcttgttg caatttagag
    12301 atttcagttt ccaaatcccg cgccttgatt tttgtcttgc gaatatttgg atttgcgacc
    12361 aattcatcgt atttttcagt aatgtcgatg taattgaatg gcacaccgta ttctttttct
    12421 acagagtaag ggctgaagag gtacatttct tcatttttac gagccaattc gtagaattta
    12481 tcaggtacta caacaccaag tgatagagtc ttgacacgta ctttttcatc agcgttttct
    12541 ttcttagttg aaaggaaagc gatgatatct gggtgaaaga cgttgaggta gacaacacca
    12601 gcaccttgac gttgccccaa ttggttggag taagagaagc tgtcttcaaa aagcttcata
    12661 acaggaacga cacctgaagc agctccttca tagcctttga taggtgcacc agcttcacga
    12721 aggttgctga gggtaattcc cacaccacca ccaatacgtg aaagttgaag agctgagttg
    12781 atagaacgtc cgatagagtt catatcatcc gtcacttgga ttaggaaaca agataccaac
    12841 tccccacgac gagcacgtcc agcattcaag aaggaaggag tagcaggttg gtagcgttgg
    12901 tggatgattt cattggcaat atcgattgca acagcttcat tcccatcagc gaaataaagg
    12961 gcgttgaaga agacacggtc ttccatattt tcaagatagt attcaccgtc attagtcttt
    13021 aaggcatatt gattgtaaaa tttataagct gccatgaatg acttgaattg gaagttttgg
    13081 tctttgataa attgagccaa ttcttccaag aactctggac ggtatttctt gataaaggct
    13141 gtttcgatgt agttgtgttc aatgaggtaa ttgattttgt ctttgattga atcaaaaacc
    13201 atagtgtttg gaactacatt ttctttaaag aaagcatcca aggcttcctt atctttatga
    13261 agcatgattt gtccattaac aggacggtta atttcgttat taagacggaa gtaagtcacg
    13321 tcttcaagat gttttaatcc cataaaattt cccttatcta attacaaaag aaaggcttct
    13381 aagttagccc taaaagcagt ttcttctgga tgatgtacta agattatgct aattgtttca
    13441 gttttcctgg ttggaaacct gaaaagactt cagttggtgt ttggataaca ggagctgcgc
    13501 taaaaccgag ctctttaact tgatcgacgt actcaggttg ctcatcaaga ttgatttcac
    13561 gataagagac attattactg tccaagaaac gcttggtcat tttacattgg acacaattgt
    13621 ttttagaata aacggttacc attgtgtaac tcctcttcaa aatttaatac tatcttagta
    13681 tatcagaaaa taaaattttg tcaatgattt gaactaaata tagtggtgtt cttttgttgt
    13741 ttttatatat aaacacaata tatagtgttt gtattgtgaa atagcaatga ttatcctata
    13801 aattgttttt aaagaaacta tatcctgtgt tttgttatct aggatagaag attttcagca
    13861 agttatctga aaggaaattg aaggaaaatc cagaaaatgc ttgaaaaaaa tcctagaaga
    13921 tggtataata ctaaattgta agggttatca catataactc aaaaaaagaa agaacaaaag
    13981 gagagtcaaa ctatggcttc taaagatttc cacgtagtgg cagaaacagg tattcacgca
    14041 cgtccagcaa cattgttggt acaaactgct agcaaatttg cttcagatat cactcttgag
    14101 tacaaaggta aatcagttaa ccttaaatca attatgggtg ttatgagtct tggtgttggt
    14161 caaggtgctg acgtaactat ctcagctgaa ggtgcagatg cagatgacgc tatcgctgca
    14221 atctcagaaa caatggaaaa agaaggattg gcataaggga aatgacagaa atgcttaaag
    14281 gaatcgcagc atctgacggt gttgcagttg caaaagcata tctactcgtt cagccggatt
    14341 tgtcatttga gactattaca gtcgaagata caaacgcaga agaagctcgc cttgatgccg
    14401 ctctacaggc atcacaagac gagctttctg ttattcgcga gaaagcagta ggtacgctcg
    14461 gtgaagaagc agctcaagtt tttgatgctc acttaatggt tcttgctgac ccagaaatga
    14521 tcagccaaat caaggaaact atccgtgcga agaaagtgaa tgcagaagca ggtctgaaag
    14581 aagttacaga tatgtttatc actatctttg aaggcatgga agacaaccca tacatgcaag
    14641 aacgcgcagc ggatatccgc gacgtgacaa aacgtgtatt ggcaaacctt cttggtaaaa
    14701 aattgccaaa cccagcttct atcaatgaag aagtgattgt gattgcgcat gacttgactc
    14761 cttcagatac agctcaattg gacaaaaact ttgtaaaagc ttttgtaacc aacattggtg
    14821 gacgtacaag ccactcagct atcatggcac gtacacttga aattgctgct gtattaggta
    14881 caaacaacat cactgaaatc gttaaagacg gtgacatcct tgctgttaac gggatcactg
    14941 gagaagtgat tatcaaccca acagatgaac aagcggcaga atttaaagca gctggtgaag
    15001 cctatgcgaa acaaaaagct gaatgggcac ttttgaaaga tgctcaaaca gtgactgctg
    15061 acggtaaaca cttcgagttg gctgccaata ttggtactcc aaaagacgtt gaaggtgtta
    15121 acaacaacgg tgcagaagct gttggacttt accgtacaga gttcttgtac atggattctc
    15181 aagacttccc aactgaagat gagcagtatg aagcatacaa ggctgttctt gaaggaatga
    15241 acggtaaacc tgttgtcgtt cgtacaatgg atatcggtgg agataaggaa cttccttact
    15301 tcgatatgcc tcacgaaatg aacccattcc ttggattccg tgctcttcgt atctctatct
    15361 ctgagactgg agatgctatg ttccgcacac aaatccgtgc tcttcttcgt gcgtctgttc
    15421 acggtcaatt gcgtatcatg ttcccaatgg ttgcgctctt gaaagaattc cgtgcagcga
    15481 aagcagtctt tgatgaagaa aaagcaaacc ttcttgctga aggtgttgca gttgcggata
    15541 acattcaagt tggtatcatg atcgagattc ctgcagcggc tatgcttgca gaccaatttg
    15601 ctaaagaagt tgacttcttc tcaattggta caaatgactt gatccaatat acaatggcag
    15661 cagaccgtat gaacgaacaa gtttcatacc tttaccaacc atacaaccca tcaatcctac
    15721 gcttgattaa caatgtgatc aaagcagctc acgctgaagg taaatgggct ggtatgtgtg
    15781 gtgagatggc tggtgaccaa caagctgttc cacttcttgt cggaatgggc ttggatgagt
    15841 tctctatgtc agcaacatct gtacttcgta cacgcagctt gatgaagaaa ctcgacacag
    15901 ctaagatgga agagtacgca aaccgtgccc ttacagaatg ctcaacaatg gaagaagttc
    15961 ttgaacttca aaaagaatac gttaattttg attaatcgaa aagtccctgc aactcagtta
    16021 cagggacttt ttttgatatt ttaaaaagaa ttttcaagaa aatctttctt ataaaaagtc
    16081 caaccttgaa aaagtagtgg tcagaacaaa aaatacttaa atggttcata aaattcttga
    16141 caagttggag atttaggagt aaactattaa ccagttaagt aatagagagg agtttctgca
    16201 atttagaaat gaattgcaac tagaaatatc aaatagaaag agagtttcga tgaaaattaa
    16261 taagaaatac cttgttggtt ctgcggcagc tttgatttta agtgtttgtt cttacgagtt
    16321 gggactgtat caagctagaa cggttaagga aaataatcgt gtttcctata tagatggaaa
    16381 acaagcgacg caaaaaacgg agaatttgac tcctgatgag gttagcaagc gtgaaggaat
    16441 caatgctgag caaatcgtca tcaagataac agaccaaggc tatgtcactt cacatggcga
    16501 ccactatcat tattacaatg gtaaggttcc ttatgatgcg attttcagtg aagaattact
    16561 catgaaagat ccaaactata agctaaaaga tgaggatatt gttaatgagg tcaagggtgg
    16621 atatgttatc aaggtagatg gaaaatacta tgtttacctt aaggatgctg cccacgcgga
    16681 taacgtccgt acaaaagagg aaatcaatcg acaaaaacaa gaacatagtc aacatcgtga
    16741 aggtgggact ccaagaaacg atggtgctgt tgccttggca cgttcgcaag gacgctatac
    16801 tacagatgat ggttatatct ttaatgcttc tgatatcata gaggatactg gtgatgctta
    16861 tatcgttcct catggagatc attaccatta cattcctaag aatgagttat cagctagcga
    16921 gttggctgct gca
//
LOCUS       DAVBOM010000048        16445 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBOM010000048 DAVBOM010000000
VERSION     DAVBOM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.048"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="VQ878_001672"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="VQ878_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3095981.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ878_001673"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ878_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET3095982.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ878_001674"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ878_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET3095983.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="VQ878_001675"
     CDS             3205..3600
                     /locus_tag="VQ878_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET3095984.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="VQ878_001676"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="VQ878_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET3095985.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="VQ878_001677"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="VQ878_001677"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET3095986.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYHKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /locus_tag="VQ878_001678"
     CDS             5389..5994
                     /locus_tag="VQ878_001678"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET3095987.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="VQ878_001679"
     CDS             5981..7180
                     /locus_tag="VQ878_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET3095988.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ878_001680"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ878_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3095989.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="VQ878_001681"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="VQ878_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET3095990.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="VQ878_001682"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="VQ878_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET3095991.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLKLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNYGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="VQ878_001683"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="VQ878_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET3095992.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="VQ878_001684"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="VQ878_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET3095993.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="VQ878_001685"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="VQ878_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET3095994.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="VQ878_001686"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="VQ878_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3095995.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="VQ878_001687"
     CDS             14213..14926
                     /locus_tag="VQ878_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET3095996.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="VQ878_001688"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="VQ878_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET3095997.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDIITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="VQ878_001689"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="VQ878_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4947 a         3074 c         3686 g         4738 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggagta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactaca ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacttga tatccagttt agaatttgct ttgacaggta tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg tcatccttgc aggttttgtt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gtattttctt ggtagtagcc
     3421 tttgagatta tcaactctgc tattgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 ttcgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacaccgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtaggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt ggcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccacaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttc tgcctgacag acaaggtctt gatttcccat ttgcggatgg agggcaagta
     4801 tttttattat ccagaccaag tgcctgaacg caagcatgcc catgttttct tccggtttga
     4861 agatgggggc acgcttgttt atgaggatgt acgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaagctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagacc ttcccagact ttgacagcag aagaagcgac
     5161 tgccattcat gaccagacca ttgctgtttt gggccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag aatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggcggacga ggcacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctcaggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagcagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt gggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgaagagca aaaatggtct
     5641 aatcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccaactt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgtattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtcagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 cactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gacttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatctg ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgcagt
     7501 aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gaaattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg ctggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tggtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggttttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaaaaa tatcataaaa
     8881 ttgtaccaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat gggactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaatcttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca attacggcca ctatggacta gctgctgact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt cgtagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgga gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaacttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt tgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg tcgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgtattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat atcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctatcg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag caatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taatattaga attgtttatc
    16441 ccaaa
//
LOCUS       DAVBOM010000049        15964 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBOM010000049 DAVBOM010000000
VERSION     DAVBOM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15964
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.049"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1205)
                     /gene="dcm"
                     /locus_tag="VQ878_001690"
     CDS             complement(<1..1205)
                     /gene="dcm"
                     /locus_tag="VQ878_001690"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET3095998.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDAEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQLLNSKDFGVPQNRE
                     RVFIIGHSRKRGTRLLFPFRREGQTTNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLIDGQFYRLRIRR
                     ITPKECFRL"
     gene            complement(1304..2083)
                     /locus_tag="VQ878_001691"
     CDS             complement(1304..2083)
                     /locus_tag="VQ878_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3095999.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQVENETAPVSHSAPRETEVSETKYSE
                     TDSLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(2080..2253)
                     /locus_tag="VQ878_001692"
     CDS             complement(2080..2253)
                     /locus_tag="VQ878_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096000.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVQLES
                     SGDLTLKELGGAL"
     gene            complement(2783..7996)
                     /locus_tag="VQ878_001693"
     CDS             complement(2783..7996)
                     /locus_tag="VQ878_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3096001.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(8040..14519)
                     /locus_tag="VQ878_001694"
     CDS             complement(8040..14519)
                     /locus_tag="VQ878_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3096002.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYNIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVSGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGT
                     NNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHA
                     DGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLID
                     KSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLW
                     DPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEI
                     LTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEK
                     VYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSIN
                     KLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALN
                     SVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKV
                     IDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNV
                     IELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQT
                     KAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFII
                     ANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEK
                     LYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGD
                     AFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPN
                     DPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAV
                     AKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIIT
                     RRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMV
                     PYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERED
                     KFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRV
                     LKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(14728..15906)
                     /locus_tag="VQ878_001695"
     CDS             complement(14728..15906)
                     /locus_tag="VQ878_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096003.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         4495 a         3248 c         2393 g         5828 t
ORIGIN      
        1 tgcagtcgaa aacactcttt aggagtgatt cgtcgtattc tcaaacggta aaattgtcca
       61 tctattaaaa caccagctac atggtaaact tgtttatctt ctccttcata gctagccact
      121 actactccca tttgaccact agttgttaat gtattcgcta taccttttcc aactctacca
      181 cgacgatact gagaacttgg tctttctaaa ttgattgaat ctccaatctc tgcttgagca
      241 tacccttttt tagttgcttc ccggactttt agaaattgga ttggttctgg aatcagtatt
      301 ttgggaattt tatctcctcc ttgcatcgta gtcagtgttg gagataagcc ctcgcttcca
      361 tagactcgac ctgtctcctt aaagctagtc ggtaaatctc caacaacgac aataccatga
      421 cgatcctgag tatttaaagt aaacatcggc tcttggtttt ccttaaagcg tctcccattt
      481 tgtctcttgt ctaatctgtc tggtgtcata caaggaatcg caaccttgaa tccttctcct
      541 tttccacgaa ctaaggttgg tgcaagacct tctgaataat agactttacc gctcattcca
      601 ctttttgatg gattcaaatt ccctagtgtt tttaaagtct cagagttagt tgtttgacct
      661 tctcgtctga aaggaaataa gagtctggta cctctctttc tagaatgtcc gataataaac
      721 accctctctc tgttttgggg aacgccaaaa tccttactgt taagcaactg ccactcaaca
      781 tcaaacccca actcatcaag tgtggtaagg attgtggtga acgtccgtcc cttatcgtga
      841 ttgagtaggc ctttaacatt ttcaagaaaa agaaaacgtg gttggatttg tttggccgcc
      901 cgagcaattt caaagaacaa agttcctcta gtatcttcaa atcccaatcg tcttcctgcg
      961 attgaaaatg cttgacaagg gaatccccca cagatgatat cgactttccc tctaagtttt
     1021 ttaaattctg catctgaaac atctcgtatg tcatgaaatt ctatttctcc ttccgtttga
     1081 aaaatggact tataagattt cctagcaaat ttatcaatct cacaaaatcc aatacactcg
     1141 tgtccaacac tttccattcc aagtcgaaat ccacctatac ctgaaaataa atcaataaat
     1201 ctcatttctt gatcacctct ttcttatcga ctaccattgt cataactgtc actccacttg
     1261 aaatgacaat aagcataact aatatccact cgattgacga catttaacca cctccttttc
     1321 taacacggtt attccaaaca gaatacaggc cattaaacac aaattcagca agtacttccg
     1381 ctcgtctaac aaagcgaaca ttgtcaagag catactgata gattctttca aaatcagtca
     1441 tagcaatttc actggctgtt tcagaaaaac cttctcgtct aaattgatct tgtaccaatc
     1501 cccaaatata atctcgatca tattttgtga ccttttctac ttttcttttc aaaataggtt
     1561 gagtattcct atcctcctca tcctcaataa ataaagaatc agtctcacta tatttagtct
     1621 cactaacttc agtctctcta ggggctgaat gtgagactgg ggccgtttca ttttcaacct
     1681 gccctagtct ttttttaaca ctaggcctgt ttgaattacc tactggggta gaagataatt
     1741 cccctaaata aatcttatta gctagtcttc ctttctcact tgaagactgt tgaacttcat
     1801 caattaagtc atattcttta agaatttttt tgatagacag taattttgac ttcgagcaac
     1861 ctaacagctt catcagttta gaattagaaa atactaaata aaccgctcct tcttcatcta
     1921 tccaaccacg actgagagat aattctaaac gatcttttaa aatagaataa gccaccttta
     1981 cttctagttt catatccata tatttctcat cctcaaaaag aattttaggt aatttgtaat
     2041 accgttctga agtttggtat tgatttgcgg taattcgttt catagcgcac ctccaagttc
     2101 tttgagtgtt aaatctccgc ttgattccaa ttgaaccaag ccactttttt ccaattcagc
     2161 cataagagag atggcttcaa caatgtcaat tcccatttca cgtactaaaa atgaaatgac
     2221 aatatagcgt gatgattgta attcttttgt cattttccct cctgaaaata aaaaaaacgg
     2281 aaagattgtg aaattccttt ccgtaacata ataaatattt gaacaccaaa ctcaacacca
     2341 aaaaaatgtt tttattgata attattgctc aatcaagcac ttataacaat gtaaaaaata
     2401 aaaatctgta ctcacaaaaa cccttgaaat tcaagggttt taagcattta ttctacttca
     2461 caatgtttta ttattttaaa tcttctagac caaccattga atagtagcca ttgagttttt
     2521 tcctttcgta gcaaggattt agatccccta ttttatttta ctatagtttg aacatagaga
     2581 gttttcaaat gaatgatgtc caaacagttc ttgttttatg acatagaaat ctactttata
     2641 ttatatcatg ccttctttat tttgtccgat gatagccttt taccctatct tttagcctat
     2701 cttttaccct atatagaaaa aagccatcaa atgatgactt ttcagaggga gcaaaaaact
     2761 gttccttcta tattctaaac atttaaatgt cttctttaaa cagtttatta aagaaaccgt
     2821 ctgtgttttt aagaagggct ttgaagacct tagatttaag agcaacagtg tgagagaagt
     2881 catctggttt cttcaaatct tcttcaactg ctttatcaaa taaaggcctt aactcatcat
     2941 agttactgat atggacgcca tcaatatcga tagcctcaaa acctttctta gctttagcaa
     3001 gaacttcccc gtaccaatgt ctcttccact cttcaagagt attaaagttt cctttcgata
     3061 ctttattaat tattagctta tcgcttagta aaccgtggtt gtttttatct gcttctgctt
     3121 tgtatttatt tgatacataa ctaataaagc cattttcata accataatag ccccacatac
     3181 ggaaagcatt gtgcttaaat gataatgaac caggagcacc ttgactcgta ttcccaccgt
     3241 aaattcctgc catcatattg acatttacgt aagctgagtt tggtgtaaaa tcttctggtc
     3301 tataacgtcc attacctgga tttccatgtt ttgtcatgaa gttattatcc actaaatcat
     3361 tgacgctaga taaagtcatt accttttctt catctttcaa atcacggata ctatcccatt
     3421 ggtttggacc taaaagatca ttatactgaa tcttagagcg catttctttg tcaatcttct
     3481 tgaaccactt actattgtct cctttaattt taggaagtac agcatcagct tctacatgat
     3541 caagcaacat catagcttca ttgtagtttc tcatgtagcg gtcaatgtca tcacgtgtct
     3601 ttaatttgtc aggatctggg ttgtaccatt ggttaccatc atttggacga tggtaagcca
     3661 tgttaattcc aagtgcgccg tattcaccat tagtcgttga gctgtcaggt gtttgcaaca
     3721 taccttgagc ataggcttca acgtctgtac cttgacgatg cttatgacca ccgaagtaaa
     3781 gcattctatc gtttacgtgt gttgtttcgt gagtaaaggc tgaaatacca aatgggctaa
     3841 tcatatccgt caccataaac aagaccttgt catcattatt tggattaggg aatattgatg
     3901 ccatagcgcc catacgccag tctctatcat ggtgtcgcca tgttggacca tataattcac
     3961 gaattggagc tatagggtta cctttactgt caaatcctcg acgacctaca ggagaaccat
     4021 tgtaggtctg gttatcccaa actggtgtcg gtaccatatt ttgactctta agaagtctat
     4081 cacgaacatt aggcagagct aatctggacc agaaatctaa ataagtttgt tgagcatgtg
     4141 caacttcatc aatcttagtt ttgaactcat tacgagcttc ttctgtatgt tttccatatt
     4201 tctcaaatga actgtacgcc atcgtgttat atgttgaaat taagaacata tgggcatctt
     4261 taagcgttag aagtggtaaa atcatacgac catgaacacc gttatctaaa ccatcgaaca
     4321 cacgatgacg tttatctttc aactctgtat ttgttgtctt aggttctgaa acataaacat
     4381 tcttagctga gtggataaac caatcattga tgtctttatc ctctgtaaac agacgcatgt
     4441 tgtattctaa gaagttacgc aaattacttt taccagtatt acctgcgatg atttcacggt
     4501 aagcatcctg agtccgatcc cctttcaagt tcttttcact tgaaccgatg ttgatgagtc
     4561 tgtcaataac acttggtgtt ttaccataaa aatcaggttt gaacatcatg atgtttttta
     4621 tacttatgtc accgtatttg atatcatagt aacgattgag ataagtcaga gccatcatga
     4681 ttttagcttt attggtttcc actttcttga gaagtgattt tatcgcagct tcatcaccat
     4741 tcaattgatg gtcttcattt tcgaccaagg atttgactaa cttatctaga ttttgcttca
     4801 cttcggcaaa gctttcttct aagtatagat ctttaatata accattctta cgttcatccg
     4861 tattctctgc aggtttatca cgtctactca ttaaatctct tacttcttgt gaaatcaatt
     4921 ccacacttga taattgagat ttaacatcag caatcaattt atcacgattt ttaacaacca
     4981 tattcggtgt ataaacaaca tcaccaagac cagatacact atattcacgc acttgttgga
     5041 ctttagaatc agtattctta gtaacatcca tttcttcctt agtaccatca gcatagtgaa
     5101 ccataatctt atcaatatct gataaatcgg tcacgaattg accatccttc atccccgtaa
     5161 cagaaaggac ttctttctta gctaagtttg aatcttctgc aagtttgtta ccttggttga
     5221 caatccattc tttattataa aatggttgaa gtttctcaat attacgataa gctaaatcac
     5281 gttcggattt gtagtcttga gttgacttat attcatcttc tcttctggtt aaacgattta
     5341 agcgattgac cacaggttcg ttgatttcgt atttatcagc agtaagtcca aaatttgcaa
     5401 ttctcttatt agcttcatct tgactaattt ctttaatttt gtcacgagaa cgtttgtatg
     5461 aatgcttacc tgaactgaca cctttgacaa caaagttacg ctctaaccag ccatttgtga
     5521 aataaccacc atcgtagtcc aaatcggaag aaccaaagaa ctcttcacca ttttcaactc
     5581 tcatcattga aatattatct tcaagtttac caaaaggaag attgctattg ataaatccac
     5641 ctgtttcaaa caaaacttta gtcttaatgg ttcctttggt gactgattta cgaattgaac
     5701 cgtatttacc aattcccata gagtcgttac cattatctgt tttagcaact aaaccaccta
     5761 tacgggctct gttagcaaca atatcagcct cgacatatgc ttttgcaaga ttacctctcc
     5821 aaatctcacc ggcaatgcca gccatatatt gacctttatc accaacacct gtaagattac
     5881 cgatgaaggc tacatttgtc aactgaccac cactatcgat tttattgacg atacccgcaa
     5941 tattgttatt agcaactaca ttaccagtta ccttaacatc ttcaacagtt gcatttttca
     6001 ccatattggc aacaggtgct attccgtcag cccaaggcat attgatatcc acattaccta
     6061 aattaatatt tttcacagaa ccattttcaa cacggtcaaa taagggacgg gcaatgttat
     6121 gaattgtata ttgtttacca tcaacacttg atagatgtcc cttaaacgta cctggaacat
     6181 attgtttgtt aggtgttggt acattcgttg cattcaaatc tgctccgatt ttaaatgtac
     6241 catttttatc agcattcatg gcatctacta actctttaaa gttataataa acgtcatcaa
     6301 cttttggaac tggtttttca atataatgaa catacttgtt acgaaccttc gttgggtctg
     6361 tatgttgaat caaatcttga gcttcggcag tgattttata aagtttctta ccttcttcag
     6421 tcacttcttc aattttatca actgctaaac gtgttacttt attatcacga ctagtaattt
     6481 ttaagtacat tttcttcaca tcttcatctg aaggtttttc agtcataaaa tcactaggtg
     6541 tttcagtacc atcgtcattt accttcacta aattagtaga tgcgatattt ttaatttcaa
     6601 cttttttcaa atccaagcga agtggtttct cttctaatgt tgcagtttct tctcccttgc
     6661 cacggtcata ggtcatagtg gtctctatct tatagtcctt gtagaatttt aaatcttcta
     6721 cctgcttatc taattgctct gaagtcaaat ctactgtttt gacaatttca tttccatctt
     6781 taattgtcgc agtaatttta ttgattgtga ctccatctgt attaactaaa tgataagaaa
     6841 gagttgcgga tcggtttaat acatttgtat ttgttctatc taaggtcaaa acaggagccg
     6901 ttttttcttt aggtttttct ttggtacctt ttacaagaat tttaggcttc atttctttca
     6961 aaatagttac tgtttcaact gggtcactga tttttttgcc atgtaactct tcatagctag
     7021 taacaatttg acgttcgcca tcctcaccaa cttgtctaac agaatcatcg cctataaatt
     7081 tgctaggatc agattcttct atagtggttt taggaatagt ctctgtccga atatcggtat
     7141 gtaaagaagg caactcttct ctttctgatg caacttctga aactgtagat attggttcag
     7201 tatactctgg aatgtcgcta acaggtggct caatcaagtt tccattttca tccactcctg
     7261 ttgtacctac tggctcagta tattctggga tgtcgttaac aggtggttca atcaagtttc
     7321 cattttcatc tactcctgtt gtccctactg gttcagtgta tgctagtttc tcatgaactt
     7381 caggctcaac aaggtttgca cctattggtt gcgtatagtc aggcttctca tgaacttccg
     7441 gttcgccttt ctctgttaca actttgggtt gctcaactgg cgaaacagtt gatgctggag
     7501 aaaccgacga aacagtttta tcatcaagct ccaagtaacc aacatatctg taaccagaaa
     7561 tttgcaacac accatcacgt ccagactcat ggatgttagc attcaaatta agtgctgaag
     7621 cagttgatag tgtaactaaa cctgtcgccc ctacaatcaa aaatgtagct atttttttat
     7681 ttctattatc ttttgtgata atcacaataa gactcccgat agctaacaaa cccaatgcag
     7741 tcataataga ttgagaactt cctgtgtttg gtagtgcgtc tttttcataa tccaaagcat
     7801 atgactcttt ggattcatca ggtctacctt gtttgagttg atcacgttca gtttgtgtca
     7861 aactactata atctaagtaa tgataagtcg atgcaccaac aactgacggt gcaaataaaa
     7921 gactccccaa gaataccgaa ccaacaatac cctttatttt ccgaatggaa aatttatctt
     7981 tttttaataa tgacaattct aatcctccac cttcactttt tatttcctaa tagtaaacac
     8041 tattttttat tctcaaaaat tgaacttcta aaatcaccgg tttggtcaag ataagcttta
     8101 aagattgctt ttttcagttt aagaactcta ctatttgtct caggatataa tttggcaact
     8161 tcatcctcag catcaaattt tactgcatct tcaatcattt tttcaagtct attaatatta
     8221 tcaatagtca ctttctgttg tcgagcccaa gaaccgtttg gatcgataaa actaacttta
     8281 tttaactttc caaatttatc ttctctttct ttatacatat ctttcttgaa atctatccaa
     8341 gaattatact ggttattaaa tacttttgaa agaacaattt catcagtaac taaacctatt
     8401 tgtttaccat atgatgtaat aacttttcct tgagctttcg cttctttttc atactgatta
     8461 gaaatatatg gaaccatacc gtctttgtac cccttggctg ccaataactc aaatgcaata
     8521 cgtcgtccca ttaaatctcc tggtgttcct attttactgc tcaatgctga ataaattggt
     8581 gagaatagat taattgtata gtagccattc cgcttataag ttgcttcatc tacataacct
     8641 cttcttgtta taatatcatg ttctatcaaa ctgttaaatg tagttaattt agtaagttct
     8701 tctggtttta atctacgtac aacattcgtt gcataaacag aatttccatc aggatcaggt
     8761 ttatattcat tttctatttt tcttaataaa tcatattttt gatttgtatc taatttagct
     8821 acagctttac cttctagtat ttcaagcatg tatattacat caaacatatt atgcatatac
     8881 ttatttagat catcaacact tccaaatcgt tgagttggat ctgctacttg aagccttgtt
     8941 gattcttctg attgatcata ttttaatatg gaattaatag tgactgttgg atcattagga
     9001 tgatcaggag cttgtagcag tcctttagca taaaactctg gtccaagtcc atttcgtctt
     9061 ccatagcctc caagataaat ttctctatct gagttatgtg tcatttcgtg tgtataagtt
     9121 accgcaccat ctttatcaag catgcgatat gccatataat agaatgcatc ccctgtagca
     9181 tatgctccat tagaattatg aacaacatta tttcccgctg gaccgaagaa atgttttata
     9241 gctggatgat tagtttcaaa agttgcttga tatgtatctt tatcttcttt ttcatctgta
     9301 ccaaatctaa atgcatcata gactagaaca cttctatata atttttcttt atttttatca
     9361 tctagtattc tataccaata atcatagtga tctctaaatc taacagccgc ttctttagct
     9421 tttttctcaa catagtcatt taaatcagtt cctgctggat gttctttact tctatatcta
     9481 tcataagcac cgaaacctat agtcgaaatg ttggctataa taaacaccga tttttcaggt
     9541 aatgttaata gcggcaacac catacttgga tatttccaag atgggctagt taatctatca
     9601 tatactccaa ttgaatatgg actaccagct attgattgct tatcacttac ctctttaata
     9661 gtagattttt cttctacaat atatgcttta gtttgttctt taaaccactc attatttgtt
     9721 ttatctggta caaatgcttt tctatatttc tctaatgcat caaataaatt attagtctta
     9781 taatttttcg ctaataaaac attataagtt ataacattat tttttgctag taagttatta
     9841 tatcccgatt tacctagttc gataacatta tctaacgctg aactatttga tttaccgaag
     9901 aaatccaagt ggtacatgac taaatctttc gcttttgtat cacgatattt gaagtcgtac
     9961 caacgctcta agtatgttaa tcctagaagt aaagcttctt tattattttt aattttctcg
    10021 attacataat tatctattac cttattgtta ttttcagcta ttgcagcatc tgcagtaaga
    10081 agttttgtca aactatcttt caaattagtt tttgtggtat tgaattgttc ttctaaatat
    10141 aactccgtta aactaacatc cttagaaaca tctaatactt ttctaattgc ctctgattta
    10201 tattctacac tatttaatgc tggtaatact tcatctaaaa tattttgata attgcgaagt
    10261 aatgtattcg gtgtataaat taagtttgta ccgcctattc tatactctgc tacatttgaa
    10321 aaatcagttt gataatttac attaagtgtc tctgatgtat tatccgcgta atatagtaat
    10381 agtttattta tacttgattt atttttgtta atatcactaa ttacttcttt atctttcata
    10441 gggactactg acaataattc tttattataa agattactac ttgtctctac taaatttccg
    10501 tacttaacaa ttgtttctct attataaaac ggtaatagtt tttcaatatt tttatatact
    10561 ttttcttttg atgaatcagc attctcaaga tttttatagt cagttacata tctagaagag
    10621 aaattaaaat cttctgtttt aatagtattt ttagatacaa aagtagcttt tttctctttt
    10681 atttgtgcat cttctaatac ttctcctctt tgaacagtag aatccttagt taagatttca
    10741 tcatcttctt gtactacgtt cacaacctta ttatttttat tactgtatgt gccatttgct
    10801 tttataccat taaaattata acctgcaata gcattaccat tcgttacatt aacatcgctt
    10861 agtacattag aaagtcgacc ggatttttct aatcctccaa ccggatccca aagattacca
    10921 actactccac caacgtttgc aaaacgttga acattattta gatttccttc agcataacta
    10981 ttactaataa gcgcactatt ttctactgca ccaactattc caccaataga ctggtctcct
    11041 tgtgttgcat ttgaagataa atcgattgat gcgaacgact tatctattaa tcccctcgga
    11101 ccagaaagtt tgcctactaa acctccgatt tgataactag caactgtttt atatgtatta
    11161 gttattctac ctgtatagct actgttagaa atagtagaat tattaacttg tgatactaat
    11221 cctcctatgc tacgttcccc agctatcgct ccatcagcat gaacgttatc aatatgagta
    11281 ttgttatttg cttctttcgc aagtgttgca gtatcgtcct ttgcggaaat attaacatct
    11341 tttagtgaaa gtttttctac tgtagcacca tttaattccc caaataatgg ttttttcaaa
    11401 ttataaatag cataatattt ctcattattt gttcctacta atattccatg gaatacatta
    11461 ttcacataac tttcttgacc atctggaagt tcaacttcac gagcatccat agttgctcct
    11521 aaacggaatg tgccattagg attgctattc attgcatcta ctaaattttt aaatgatgta
    11581 tataccccag tttcactttg ctgagttttt ggtaaatagt atgtataatt ttctagtaca
    11641 ttattatttt catgttgtat cagactattt gcacttgcta ctatcttata aacatctcta
    11701 ttatctttag tatcattagt aatgcttgta actggtagca tcacatcttt aaagttctct
    11761 gatttaactt tcataaagta attttctgca ttacttggta aagaagcaag tgaagttaca
    11821 tgtcgatact tattaccatc ttttgaatat agttctacag aagatatatt tctaagttct
    11881 aatttcttaa taacttcttt ttcatcttta gcgtcatctt ttttctcatc tttatgacga
    11941 taaagttcat cgtatactgg tggaatttca ttacctgcta taatactctt aatccaagct
    12001 aattgtgtag gagataaaat caatccgcct gagcgatttt gtgctccatt ttgatgcaca
    12061 ccaataactt caccattagc attaaatatt cctccaccac tcataccagg atttccacct
    12121 tgatattgaa caccgtaggt gttattcgca tattcttgtt ccatttctac cgtagcatct
    12181 tttaagtgcg tatatttccc agctggatat ccatgaacat ttagtttgtc attaagattt
    12241 actttcgaat aatttttaac taattctaca tgttctctgc cagttgtttc aggtagctta
    12301 atcactgcta aatcatagat aaatcctttt ggataatctt ttttattata aaaatgaata
    12361 ttgttagcag taaatgttcc tttttgtcca tcaggagtca cccactcata tacgttttta
    12421 gatttatcac ctctaaattc gccagtagta ttatcagtag aattattaat gaaattatgt
    12481 gctactgtta aaagtacatt tggtgcaata aaagtagctg atcctactcc agtaaccttc
    12541 gacgaatctg taataaagtt catattaatt aatgcactag attttttctg aatactcatt
    12601 tcttctggtg tattagtatt ttcattattt ggtttagtat cttctgcact aggttgttcg
    12661 attttaccag tatattcttt cagtgcttct actttttctg gttctactat tgctccggct
    12721 tgcacccctg tgtattctgg tagtggtgct atctgctctg gttcaacaat agcgccagcc
    12781 tgcacccctg tgtattcttt tgatggttct actttttctg gttctactat tgctccggct
    12841 tgcactcctg tgtattcctt cggtgcttct accttctctg gttcgactat cgctccagcc
    12901 tgcactcctg tgtattcctt cggtgcttct actttctctg gctcgactat cgctccggct
    12961 tgcacccctg tgtattctgg tagtggtgct acctgctctg gttcaacaat agcgccagct
    13021 tgtactccag catattccgg ttcaactttt tcaggttcaa caatagctcc agcttgtact
    13081 cctgtatatt ctggtagcgg ttctacctgc tctggatcac ccttgtcagt catgactgcc
    13141 tctggtaacg ctggttgaac ttctggtacg cctttatcac ttactacagc ttctggcaac
    13201 tctggttgga ctgctgactc acctttgtcg gttaatacag ctgctggtag ttcaggctga
    13261 attgcgggtt caacaatagc tccagactgt acttccttat gttctgcacc agtctcagct
    13321 tgttccttta taacttgagc ttttttagta cctttttcga ctattcttga aacaggcgca
    13381 gtcgttgaag ttgaaataat ttctcgtgaa acttcttcat tgtttacaga aaatattctg
    13441 acgatttcaa ctttcttacc taatgcacct tcttgtttta ctcttacagt tccttctgct
    13501 aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtttctat agtttcgtca
    13561 cgatataaga gttccggttt gttcaactga cctgatagca cttcatcctg tggatttaat
    13621 gtatttaccc cagtcttttc ctttggagaa atcttctcct ctttcttcgt ttctagattc
    13681 ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt tcttggattg
    13741 attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt agttgaagaa
    13801 acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa atttggtgta
    13861 acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc ttgattactt
    13921 acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt gtaacctgaa
    13981 atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt attgtaattt
    14041 agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc cattcccgca
    14101 accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac agcaaaaatt
    14161 aaaattccca gagcagctaa gctagcacca gaaactaggg cttgcctctc attcttgctt
    14221 ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac aagataataa
    14281 gtttcatcat cattctccac gtatgtcgga atattataga caagctgctt cttttcttct
    14341 gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc ttgagcatcc
    14401 acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc agatacaagt
    14461 cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata cttttccatt
    14521 attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat tagtgtatta
    14581 tctattatct atagaaaagg cagtatacct taattatact cttaatttac aaaaaagtct
    14641 taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca ataacaccta
    14701 ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa atggtttgag
    14761 gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat ggtcttcctg
    14821 caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt caaaggcttt
    14881 cattttatag aaaaagtcga tgagatgatc ggacaggtat tcagttgaaa agggtacttc
    14941 accacttttt cgatattcta ataagagcct agaaaatcga gctttttctt caggaagctc
    15001 acgaaaatag gaattgagga gccaagtctg cttctgtttt ctttcaattg gatcctgact
    15061 ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga tagcccgttc
    15121 tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag tcagggtctc
    15181 tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta gaaccagatt
    15241 gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg cctggatacg
    15301 gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga gttggtcatc
    15361 cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca tccgagcctt
    15421 tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga aaagctggta
    15481 gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt tttcccagag
    15541 ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt cttttttctg
    15601 agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt ccaattgctg
    15661 gtcaagggac aatcgatgaa aatgacgaac acagtcgcta ccaattggaa agaggcgttg
    15721 gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttccac agacacaatt
    15781 gctacggccg ataccgttaa aaatcaagga aacttcattc cattccttgg tagcttgttc
    15841 ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc taactggaag
    15901 tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta gaaagctagc
    15961 cgca
//
LOCUS       DAVBOM010000050        14745 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBOM010000050 DAVBOM010000000
VERSION     DAVBOM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.050"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            83..880
                     /locus_tag="VQ878_001696"
     CDS             83..880
                     /locus_tag="VQ878_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET3096004.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VQ878_001697"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VQ878_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VQ878_001698"
     CDS             2383..3657
                     /locus_tag="VQ878_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET3096005.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VQ878_001699"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VQ878_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET3096006.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDTSGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VQ878_001700"
     CDS             4786..5088
                     /locus_tag="VQ878_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3096007.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VQ878_001701"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VQ878_001701"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET3096008.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VQ878_001702"
     CDS             5962..7302
                     /locus_tag="VQ878_001702"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET3096009.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VQ878_001703"
     CDS             7280..7492
                     /locus_tag="VQ878_001703"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET3096010.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VQ878_001704"
     CDS             7489..8364
                     /locus_tag="VQ878_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET3096011.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VQ878_001705"
     CDS             8357..9172
                     /locus_tag="VQ878_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET3096012.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VQ878_001706"
     CDS             9165..9596
                     /locus_tag="VQ878_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3096013.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VQ878_001707"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VQ878_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET3096014.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VQ878_001708"
     CDS             11272..12000
                     /locus_tag="VQ878_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET3096015.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VQ878_001709"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VQ878_001709"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET3096016.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VQ878_001710"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VQ878_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14360..>14745
                     /locus_tag="VQ878_001711"
     CDS             14360..>14745
                     /locus_tag="VQ878_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3096017.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLM"
BASE COUNT         4391 a         2669 c         3481 g         4204 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ttcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagttatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt tgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gcattggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggccatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttag ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa tgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggccgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatacta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgct aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccagaatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaaacggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtttatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgaaacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgaa atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccat ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccatttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aaatacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aatcatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa
    14281 agaatagaaa gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat
    14341 ggaaagaagg gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
    14401 cttagaagcg gataatcaag aacaactctt tgatcaggta gcaagcttgt tggaagaacg
    14461 agaaattgtc actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
    14521 tggtttagat atggaatttc taggaaagga cttgccaaat gtagcgattc ctcacacaga
    14581 tattgttcat aatctagctg aaaaagtggt ggttgttcga ttagaaaaac cagtaacttt
    14641 tcacaatatg attgcgccag gtaaggaagt agaagtatcc ctactcttct ttatcattaa
    14701 caattcaagt tcaagtcaaa caaatattct ggctcagttg atgga
//
LOCUS       DAVBOM010000051        14344 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBOM010000051 DAVBOM010000000
VERSION     DAVBOM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.051"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(83..646)
                     /locus_tag="VQ878_001712"
     CDS             complement(83..646)
                     /locus_tag="VQ878_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3096018.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ878_001713"
     CDS             complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ878_001713"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET3096019.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ878_001714"
     CDS             complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ878_001714"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET3096020.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2112..3782
                     /locus_tag="VQ878_001715"
     CDS             2112..3782
                     /locus_tag="VQ878_001715"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET3096021.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            4110..5285
                     /gene="mutY"
                     /locus_tag="VQ878_001716"
     CDS             4110..5285
                     /gene="mutY"
                     /locus_tag="VQ878_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET3096022.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            5341..6045
                     /locus_tag="VQ878_001717"
     CDS             5341..6045
                     /locus_tag="VQ878_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3096023.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            6038..7387
                     /gene="vicK"
                     /locus_tag="VQ878_001718"
     CDS             6038..7387
                     /gene="vicK"
                     /locus_tag="VQ878_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET3096024.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            7389..8198
                     /locus_tag="VQ878_001719"
     CDS             7389..8198
                     /locus_tag="VQ878_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3096025.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKNKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            8289..8531
                     /locus_tag="VQ878_001720"
     CDS             8289..8531
                     /locus_tag="VQ878_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET3096026.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVANLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            8533..8787
                     /locus_tag="VQ878_001721"
     CDS             8533..8787
                     /locus_tag="VQ878_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3096027.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            8834..9577
                     /locus_tag="VQ878_001722"
     CDS             8834..9577
                     /locus_tag="VQ878_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET3096028.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLIGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDVVPTSIFGKWLAVLLMLVGIGTIGMLTSTLTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(9867..10853)
                     /locus_tag="VQ878_001723"
     CDS             complement(9867..10853)
                     /locus_tag="VQ878_001723"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET3096029.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ878_001724"
     CDS             11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ878_001724"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET3096030.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            13515..14258
                     /gene="srtA"
                     /locus_tag="VQ878_001725"
     CDS             13515..14258
                     /gene="srtA"
                     /locus_tag="VQ878_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET3096031.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4393 a         2477 c         3188 g         4286 t
ORIGIN      
        1 ttttactata gtaaagattt cattaaaaag aaactgtata gagcaaaatc tccaccttca
       61 ggtttgaaag cggagattgt ttttattttt tcaaggtttg tagtcgtgga acaatggcta
      121 gggttagaat tgcagaaatg accaattcag caattgaatt tgttgagata acggttgcca
      181 gaagaagttg gatatttcca ttataaacat ttccaaatag gaagaagatt cctccaagga
      241 caaagatagt atttgtcaag gaaccaagag ccccagctaa aatcagacca gtcttgtttt
      301 tcatcagttt atagactaag taaggagtta aaccaatcaa aatacgtggg acaatggcaa
      361 tgatagctga gtagatgttt ccgtttggta cgaagggaga gaagaggtag cttgtcggta
      421 gaatcgtaat cgtgttaacc gtcaagctaa gtaatcccat caaaaatcca agtgtaaccc
      481 caactcgtgg accataaata atgctggcaa taatgacagg aatatgaaca atggtcggtt
      541 tgattggaaa tggaaaaagg ttaaagataa gtgagctcag aaagtgtatc acgagcatgg
      601 tagcaaaaaa gatagcaatg ggtgcaatat tagagcgttt tttcatcgag agtttccttt
      661 attctttcta aaataattgt gaggtcagct aaagctcctc gtccgtggtc tccacaagct
      721 agtagggatt ccttaggagc aatcagctga tagccgtagg tttctaatgt tttcagatta
      781 ttctgagtta ctggatggtc atacattttt gtattcatag caggagctat tagtttggga
      841 atatgacttg gtagggctag agctgtactg gttaccatgt tgtccgcaaa tccgtgagct
      901 agttttgcaa tagtgttagc agttgcaggt accacgataa ataaatctgc tttttttcca
      961 agttcgatat gattgacctg atcaggatag ggttccttca tgacatccaa gtggacagga
     1021 ttctgtgaga gtacctgtag tgtcaaaggt tggataaact ctgtagcagc ctgagtcatt
     1081 aagacagtga cttgatggcc ttgttttttt agagaactga ctaaatctgc cgacttataa
     1141 gaggcgattg aacccgttac agccaagaga atgtttgcca tagttttcct ttctaagaat
     1201 gataggcttg aattttttca aggaggagtt ctgcaatttc ttctttagtc tggactgttt
     1261 gaagctgatt tttctcaaca aatatagctc ggtgctgatc tgctgaaatt tgagtcaggt
     1321 cattcgcgat gattaaatct gcttgattct tgataagact ttttcgtgca atgtcaacca
     1381 gatgatcttc ggtaacatca accagcagtt tgaaaccaat cagatgaata gtaggattcc
     1441 attccttgac tagggatatg attttgggtg tctttttaag gaacaaaacc tgaacctcat
     1501 cagttgaaga aatcttggcc tgatgattct gcttgcttaa aaattctttt agattggagc
     1561 tagcctgaac ttcctcaagc cctgtcatat aaacaggagt gtagtcagaa acagccattg
     1621 agtggatcaa gacctgataa tcctgaacac gttcttgcat ttctattaga aggtccttgg
     1681 tattggtaat ttctcgaata cttaggttag gatgaggctc tggcttcaga gctcgttttg
     1741 tcgtaattaa acaaacttca tgccctgcag aaagcaaagt ctctgtgata attttcccca
     1801 agtgacctgt agaatggtta gtgatagagc ggacgctatc gatagcttca ctggtaccgc
     1861 ccgatgtaac taaaattttc atagcactat tgtacacaaa aataagcggt aagtaaaatg
     1921 aaagtgataa atttttggta aaaacgaaga tttattatag tttcaaacta taaagccata
     1981 taaaatttaa gaaaggactc taaaagtctt aaaaacagag atatttacga acgtttagag
     2041 agttttagga tgttaaaaat cttgttttgt gatataatga attatcatat aagaggttag
     2101 aggaattttg aatgaaaaca gatattgaaa tcgcacagag tattgagttg aagccaattg
     2161 ttgatgttgt agagaaactt ggtatttctt atgacgattt ggagttgtac ggaaagtaca
     2221 aggctaaact cagctttgat aaaattcgtg cagttgagag caatccagtc ggtaaattga
     2281 tcttggttac tgccatcaac ccaacacctg caggtgaagg aaagtcgacg cttaccattg
     2341 gtcttgcgga tgccttgaac aagattggca agaaaaccat gattgctatc cgcgaaccgt
     2401 ctcttggtcc agtcatgggg atcaagggtg gtgctgctgg tggtgggtat gcacaagttc
     2461 tgccaatgga agacatcaac ctccacttta ctggagatat gcatgctatt acaactgcca
     2521 acaatgccct ttctgccttg attgacaacc acttgcacca agggaatgag ctgggaattg
     2581 atcaacgtcg tatcctctgg aaacgcgttg tggacttgaa cgaccgtgcg ctccgccatg
     2641 tgactgttgg tcttggtggt cctctaaacg gtattccacg tgaggacggt tttgatatta
     2701 cagttgcttc agaaatcatg gcaattcttt gcttggcaac ggacatcgag gacttgaaac
     2761 gtcgtttggc gaatatcgtt attggttatc gctatgaccg tacgcctgtt tctgtaggtg
     2821 atttgcaggt tgagggtgcc ttggctttga ttttgaagga tgctattaag ccaaacttgg
     2881 ttcagacaat ttacggtaca cctgcctttg tacacggtgg tccatttgcc aatatcgctc
     2941 atggctgtaa ctctgttttg gcgacgacaa cagcccttca cttggctgat tacactgtta
     3001 ctgaagctgg ttttggtgcg gatcttggtg ctgagaaatt ccttgatatc aagacaccaa
     3061 acttgccaac atctccagat gcagttgtta ttgtcgcaac ccttcgtgcc cttaagatga
     3121 atggtggtgt ggctaaagac gctctgactg aagaaaatgt agaggcagtt cgtgcaggtt
     3181 ttgctaactt gaaacgccac gttgaaaata tccgtaagtt cggtattcca gcagttgtag
     3241 ctattaacga atttgtatct gatacagaag ctgaaattgc agtcttaaaa gaactctgtg
     3301 cctcaatcga tgtaccagtt gaattggcta gtgtctgggc tgatggagca gaaggtggag
     3361 tagcacttgc cgaaacagtt gttaagacaa ttgctgaaaa tccagctaac tataaacgtt
     3421 tgtacgataa tgatctttct gtccaagaaa agattgaaaa aattgtcact gaaatctatc
     3481 gtggtagcaa agtgaacttt gagaagaaag ctcaaacaca aattgctcaa atcgttcaaa
     3541 acggttggga caaattgcca atttgtatgg ctaaaactca atacagtttc tcagacaatc
     3601 caaatgcgct tggagcacca gaaaactttg aaattaccat tcgtgaattg gtaccaaaat
     3661 taggtgcagg cttcatcgtt gccttaactg gtgatgttat gaccatgcca ggtcttccaa
     3721 aacgtccagc agctctcaac atggatgttg aaagcgatgg aactgtgcta ggcttgttct
     3781 agtggattga aattgacttt aagtgagttt ggaaataata tccaagctca ttttttctca
     3841 gactgcaagc agttcatcaa taagatttat actcttcgaa aatcttttca aactacgtca
     3901 gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac aacctcaaaa
     3961 cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     4021 aagtagatag aaaagttata tactatctat tgaaaatatt ataaatcaga tacaaagaca
     4081 ggtgaaacct tctgtgttat actagagata tgttagattt gaaagaatac ggtatcgtca
     4141 tgtggccgga ggagaaagtc atttctttcc gtgagaaact tctcgcttgg tatgatgaaa
     4201 acaaaagaga tttgccttgg aggagaagta aaaatcctta tcacatctgg gtatctgaaa
     4261 tcatgcttca gcagaccagg gtggatacag ttatccctta ctacgaaaga tttttggact
     4321 ggtttccaac tgtcgaaagt ctggcaactg cgcctgagga gagtttactg aaagcttggg
     4381 agggcttggg ctattattct cgagttcgca atatgcaggc tgcagcccag cagattatga
     4441 ctgactttgg tggccaattt ccaaatacct atgaaggaat ttccagcttg aaagggattg
     4501 gaccttacac agcaggagcc atttccagta ttgcttttaa cttgcctgag ccagctgtag
     4561 atggtaatgt catgcgggtc ttggcgcgtc tgtttgaagt caaccacgat attgggattc
     4621 caagtaatcg aaaaattttt caggcaatga tggagatctt gattaatcca gatcgtccgg
     4681 gtgattttaa tcaagccttg atggacttag ggtctgatat tgagtctcct gtaaatccca
     4741 gacctgaaga aagcccagtc aaggacttta gtgcggcata tcagaatgga accatggacc
     4801 gttatccaat taaatctcct aagaaaaagc cggttcctat ttatcttaaa gccttagttg
     4861 tgaaaaattc tcaaggacaa tttttacttg aaaaaaatga aagcgaaaag ctcttggcag
     4921 gtttttggca tttccccttt atagaagttg ataacttttc gcaagaagag cagtttgacc
     4981 tctttcatca ggttgcggaa gaaagtgtga actctggccc cagtccagaa gagagtttcc
     5041 agcaggacta tgacctagat gttgattggc ttgatgtttg ttttgataca gtccagcatg
     5101 tttttagtca tcgaaaatgg catgtacaga ttgtagcagg tcaggtgagt gacttccatg
     5161 atttttcaga tagggaagtt cgttggcttt caccagaaga attcaagaat tacccacttg
     5221 ccaaacccca acaaaaaatc tggcaggctt atgcacaagc caacttagac agtagccaag
     5281 actagctatt gtgtcttctg actatttttt tggtataata gtagagaaaa aggtgaacat
     5341 atgaaaaaaa tactaattgt agatgatgag aaaccaatct cggatattat caagtttaat
     5401 atgaccaagg aaggttacga agttgtaact gcttttaatg gtcgtgaagc gctagagcaa
     5461 tttgaagcag agcaaccaga tattattatt ctggatttga tgcttccaga aattgatggt
     5521 ttagaagttg ctaagaccat tcgtaagaca agcagtgtgc ccattcttat gctttcagcc
     5581 aaagatagtg aatttgataa ggttatcggt ttggaacttg gggcagatga ctatgtaacg
     5641 aaacccttct ccaatcgtga gttgcaggcg cgtgttaaag ctcttctgcg tcgttctcaa
     5701 cctatgccag tagatggtca ggaagcagat agtaaacctc aacctatcca aattggggat
     5761 ttagaaattg ttccagacgc ctacgtggct aaaaaatatg gcgaagaact agacttaacc
     5821 catcgtgaat ttgagctttt gtatcattta gcatcgcata caggtcaagt catcacgcgc
     5881 gaacacttgc ttgagactgt ctggggttat gactattttg gtgatgtccg tacagttgat
     5941 gtgactgtac gacgtctgcg tgagaagatt gaagatacgc ccagccgacc agagtatatc
     6001 ttgacacgcc gtggtgtagg gtattacatg agaaataatg cttgatttac tgaaacaaac
     6061 catttttacc agagatttta tctttatcct gattttgtta ggtttcatcc ttgttgtgac
     6121 cctcttatta ctggaaaata gacgtgataa tattcagttg aagcaaatca atcaaaaggt
     6181 taaagatttg attgcaggag attattccaa ggttcttgat atgcaaggtg ggtctgaaat
     6241 caccaatatt accaataatt tgaatgactt gtcggaggtt attcgtctca ctcaggaaaa
     6301 tctagaacaa gagagtaaga ggctaaatag tattctgttt tatatgacag atggggttct
     6361 tgcgaccaac cgtcggggtc agattatcat gattaacgat acagccaaga agcaactggg
     6421 gttggttaag gaagatgttc tgaatagaag cattttggaa ttgctcaaga tagaagaaaa
     6481 ctatgaattg cgtgatttga ttacccaaag tccagaattg ttgctagatt cccaagatat
     6541 caatggtgaa tatttgaacc ttcgagttcg ctttgccttg atacgtcgag agtctggctt
     6601 tatttcaggt ttggtggctg ttttgcatga tacgacggag caggagaagg aagaacgcga
     6661 acgaagactc tttgtttcca atgttagcca tgagttacgg actcctctga ctagcgtaaa
     6721 atcctatctt gaagccttgg atgagggggc tttgtgtgaa actgtagcac cagactttat
     6781 caaggtttct cttgatgaga ccaaccgtat gatgcgcatg gtgacggatc tcctccatct
     6841 ttcacgtatt gataatgcta ccagtcacct agatgtggaa ctgattaact tcactgcttt
     6901 tattaccttt atcctcaatc gttttgacaa gatgaaagga caggaaaagg agaaaaaata
     6961 tgagttggtg agagattatc ccatcaattc tatctggatg gaaattgata cagataagat
     7021 gacgcaggtt gtcgacaata ttttaaataa tgctattaaa tattcgccag atgggggtaa
     7081 aatcactgtc agaatgaaga caactgaaga ccagatgatt ttatccattt ctgaccacgg
     7141 tttggggatt cctaagcagg atttaccacg tatctttgac cgtttctatc gtgtggatcg
     7201 tgctagaagt cgtgcacaag gtggtacagg tctaggactg tctatcgcta aagaaattat
     7261 caaacaacat aagggcttta tttgggccaa gagtgaatac ggcaagggtt caacctttac
     7321 cattgtgctc ccttatgata aggatgcagt gaaagaagaa gtatgggagg atgaagtaga
     7381 agactagaat gagtgaaata ggctttaaat acagtatttt agcgtcgggt tccagtggaa
     7441 attcttttta tctggaaacc tcaaaaaata agcttttagt agatgcaggc ttgtctggca
     7501 agaaaattac cagtctgcta gctgaaatta accgtaagcc agaagacctg gatgccatct
     7561 tgattaccca tgagcattca gatcatatcc atggagtagg cgttttggct cgcaagtatg
     7621 gtatggatct ttatgccaat gaaaagacct ggcaagctat ggaaaatagt aaatatcttg
     7681 gcaaggtgga ttcttcgcaa aagcatattt ttgaaatggg taaaaccaaa acctttggag
     7741 atatcgacat cgagagtttt ggtgtaagcc atgatgcagt cgcaccgcag ttctatcgct
     7801 ttatgaagga tgataagagt tttgtccttt tgacagatac aggttatgtc agtgaccgta
     7861 tggcgggcat tgtcgaaaat gcggatggct atcttatcga ggccaaccat gatgtagaga
     7921 ttttgcgatc aggttcttac gcttggcgac tcaaacaacg aatcctatct gaccttggtc
     7981 acctttctaa cgaggacggt gctgaagcta tgattcggac gctaggaaat cgtactaaga
     8041 agatttacct tgggcattta tctaaggaaa ataatatcaa ggaactggct catatgacca
     8101 tggtcaatca gctggctcaa gctgatctgg gagtcggagt agactttaag gtttatgata
     8161 cctcaccaga taccgcaaca ccattgacag agatataaaa agaacgctga gaaggtgttc
     8221 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
     8281 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
     8341 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
     8401 ccctagaaga tgaatacgat gctcgtgtgg caaatttagc ctatcaagag tatttagaag
     8461 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
     8521 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
     8581 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaaggc
     8641 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
     8701 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
     8761 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacaata tagaaagtaa
     8821 ggagagtaaa aatttgaaga aaaaatgctt ttttgcagat tattatgata caacaattat
     8881 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgattgattt
     8941 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
     9001 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
     9061 tttattggct attctccctt taaatgctat tttcacagtt tttcgattag ggcgtatctt
     9121 tcgtttagtt aaactaacaa aattactgaa actgactcgt ttacttagaa taattggact
     9181 tataggtaaa ttagaaagaa aaattagtag attcttacgg acaaatggcc tgatttatat
     9241 cttatatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     9301 aaaatccttc tcagatagtc tctggtgggc tcttgtgacg gtaactactg ttggttatgg
     9361 tgatgttgtt cctacttcaa tttttggtaa atggttagct gtcttattaa tgcttgtcgg
     9421 tattgggaca ataggaatgt taacgagtac cttgacgaac ttttttgtaa aggataatcc
     9481 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagccaaa gaatattaat
     9541 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     9601 aatatcataa aggtgagaca aaacaaaact tgattcgagg agaaatcaag taagtcttga
     9661 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     9721 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     9781 tgatagggtg ctatttcaac ttcaacctac tataatacag aaaaaaaaca actccctgat
     9841 gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa ttctggattt
     9901 ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat tttttgagtt
     9961 tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc aacaacagct
    10021 ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac tgaaagtgga
    10081 agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc tactgcgata
    10141 ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg aacaccttcg
    10201 aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg
    10261 tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc
    10321 atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag tgcttgacgg
    10381 aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg gaaaccagag
    10441 aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag gaagatacct
    10501 ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag gtttttacct
    10561 acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat cacaacaagg
    10621 tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga agtgaaggca
    10681 agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg tggaatttcg
    10741 ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta agatgaacct
    10801 acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt cattgtttta
    10861 aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta tcacttttaa
    10921 aaaactttgt cacgaatatg ccttatagtt ctcgatgtaa acgttttagt ggtttagagg
    10981 ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga aatgaggcat
    11041 ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat gaaggcaagt
    11101 tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc
    11161 ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt gaccccagac
    11221 aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata tcacccacac
    11281 ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag ctaccgttac
    11341 atgcttgtag atggtcacgg gaattttggt tccatggatg gagatagtgc tgccgctcaa
    11401 cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa
    11461 aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt ggtcttgcca
    11521 gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg gatggcaacc
    11581 aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt catggataat
    11641 cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt tccaactggt
    11701 gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa aggttcgatt
    11761 gccctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg catcgttgta
    11821 acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt tcgcttggtt
    11881 caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt
    11941 cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa taacctcttc
    12001 aaaatgaccc aaatgcaaac caattttggt ttcaatatgc tcgctatcca aaatggtata
    12061 ccgaaaattt tgtctcttcg tcagattttg gatgcttata tcgagcacca aaaagaagtg
    12121 gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca tatcttagaa
    12181 ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg tgctagtgaa
    12241 acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga acgtcaaagt
    12301 caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa
    12361 tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct tgctaagcct
    12421 gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa attttctgat
    12481 aagcgccgta cagagttgat gattggacag gtcttgagtc tcgaggatga ggacttgatt
    12541 gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg tttggatcag
    12601 gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat
    12661 gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct cttcttcaca
    12721 aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc
    12781 aaagggctac cagtagtcaa tctcttgaaa ttggatgaag acgaaagtat tcagacggtt
    12841 atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac ccgtcacggt
    12901 attgtgaaga gaaccagtgt taaggagttt gccaatattc gtcaaaatgg tctcaaagcg
    12961 ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tggcagaagg agatatggat
    13021 attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc cgttcgtggt
    13081 atgagtcgta tcgccactgg tgtaaaaggt gttaaccttc gtgaaggaga cacagttgtt
    13141 ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa aggatatggt
    13201 aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca
    13261 gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca aggggatgag
    13321 gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc caatatttca
    13381 caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga tgctcagata
    13441 gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca
    13501 gaaggtgaag aataatgtct caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc
    13561 tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt tttaatactc
    13621 aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc caggtatcaa
    13681 aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat tctgtcaaag
    13741 ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta ccagttattg
    13801 ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga cttgataatg
    13861 ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga gaaggaaatt
    13921 atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg ttattttctc
    13981 ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat aaagtttata
    14041 cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa gttgatgata
    14101 gagatggggt caatgaaatc acattagtaa cctgtgaaga ccttgctgct acagaacgta
    14161 ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct gatgaaattc
    14221 taacagcttt caatcaacca tataaacaat tttattaata caaatcagtg aaatcatgga
    14281 tttcactgat tttttaagat tttcataaaa atatagtaaa atgaaataag aataggacga
    14341 atcg
//
LOCUS       DAVBOM010000052        14208 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBOM010000052 DAVBOM010000000
VERSION     DAVBOM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.052"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..211
                     /locus_tag="VQ878_001726"
     CDS             <1..211
                     /locus_tag="VQ878_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3096032.1"
                     /translation="PRKSSKLKPLTVEDQAYNHALSKERSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(526..2217)
                     /locus_tag="VQ878_001727"
     CDS             complement(526..2217)
                     /locus_tag="VQ878_001727"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET3096033.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2353..2799
                     /gene="argR"
                     /locus_tag="VQ878_001728"
     CDS             2353..2799
                     /gene="argR"
                     /locus_tag="VQ878_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3096034.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2850..5384
                     /gene="mutS"
                     /locus_tag="VQ878_001729"
     CDS             2850..5384
                     /gene="mutS"
                     /locus_tag="VQ878_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET3096035.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5531..7225
                     /gene="patA"
                     /locus_tag="VQ878_001730"
     CDS             5531..7225
                     /gene="patA"
                     /locus_tag="VQ878_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET3096036.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDNEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7555..7818)
                     /locus_tag="VQ878_001731"
                     /pseudo
     CDS             complement(7555..7818)
                     /locus_tag="VQ878_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8016..9782
                     /gene="patB"
                     /locus_tag="VQ878_001732"
     CDS             8016..9782
                     /gene="patB"
                     /locus_tag="VQ878_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET3096037.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMCNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9921..10610
                     /locus_tag="VQ878_001733"
     CDS             9921..10610
                     /locus_tag="VQ878_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3096038.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10614..10793
                     /locus_tag="VQ878_001734"
     CDS             10614..10793
                     /locus_tag="VQ878_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096039.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10780..12129
                     /locus_tag="VQ878_001735"
     CDS             10780..12129
                     /locus_tag="VQ878_001735"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET3096040.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12253..13713
                     /locus_tag="VQ878_001736"
     CDS             12253..13713
                     /locus_tag="VQ878_001736"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET3096041.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYESLGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13727..14161
                     /locus_tag="VQ878_001737"
     CDS             13727..14161
                     /locus_tag="VQ878_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3096042.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4160 a         2749 c         3194 g         4105 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccact aacagttgaa gatcaagcct ataaccatgc
       61 gctatccaag gagagaagca aggtcgagaa catctttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc
      181 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctatta tttggttagg
      241 tgaattagtg aagcgtttag gcaagtgtct ctggttacga cgtcatggcc tctaaatcga
      301 ttatatttag gggtcatgac tagtgaagca gttagctagt tcgcatataa gcggctagcg
      361 tctaacaatt aggaacttta gttccaataa ctttaagatt acgacgtttt aggacataaa
      421 tcgatcatat ttatgtccta aaactagtga agcgcctagc caaagtccga ataggatttg
      481 gcgttagtta cttagattgc tttgcaatca agtaactttg gcgatttaca tcttctctgg
      541 cgcttctact ccaagcaagc gaagggcttc ttttagaacg actgcggttg cgtagctgag
      601 ggctagacgg ctgtcgcgtt ctgggctttc atccaagata cgtgtatgtg catagtattt
      661 gttaaaggat tgagctaggc taattgcaaa tttagcaatg atagaaggtt caaagttatc
      721 tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt ttaatgattt cccagctttc
      781 agtatcattc aagctatagt tgccagctgt ttctggtttg aaatcggctt tgcgtaagat
      841 agattggata cgagcgtagg catattgaac gtaaggtcca gtttcaccct cgaaggatac
      901 catagcttct aggtcgaagt cgtatccatt tgtacggtcg gttttgaggt catagaattt
      961 aatggctcca accccaacag catgtgctac ttggtctttg ttttctagtt caggattttt
     1021 agcctcgatt tggaccttgg cacggctaac agcctctgca acagtaggct ctagcaagat
     1081 gacattccct ttacgagtag agagcttctt cccttccttt gtaaccaaac caaaaggaac
     1141 gtgagtaatg tcgtcactcc agtcgtagcc catctcttgc aagacagctt tgagctgttt
     1201 aaagtgggca gattgttctt gaccaacgac atagatagat ttagcaaatt ggtattcgtt
     1261 tttacggtaa agggctgcag ccaagtcacg tgtgatatag agagttgcac catcagactt
     1321 cttgatgagg gctggatgtt caattccata tttctcaaga ttcacaactt gggcaccttc
     1381 tgattcaaga agtagtcctt tttcagaaag aatgtctaca actgcatcca tcttatcatt
     1441 gtagaaggct tctccgttat agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt
     1501 aaattccact aaactttcat cgcggaacca ttgccaaaga gcgagagctt cctcatctcc
     1561 attttcaagt ttacggaacc attcgcgcgc ttcttcatcc aagctagggt cattttcagc
     1621 ttcagcgttg atgcggacat agagtttaag gagttcatcg attggatgag cttttacagc
     1681 ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc ccaaattgtt taccccagtc
     1741 tcccaaatgg ttgaccttga ccgtttgata accgattttt tggaaaatat gtgacaagct
     1801 atctccgata acagttgaac gcaggtggcc aatagaaaat ggtttagcga tattcggact
     1861 agacatgtcg ataacaacat tttcttgttt gccaatattt tggtcagcat agtgttcttt
     1921 ttcagttgta acagcttgca atacttgagc agaaatggca gatttatcaa ggaaaaagtt
     1981 aacgtaaggt cctgttgcga caactttttc aaaggcttgg ctgttcattt tttcagccag
     2041 ttcagccgca atcatttgtg gtgctttacg ttcgactttg gcaagagaaa aagcagggaa
     2101 agcgatgtca cccatttctg agtttttagg ggtttccagt aactttaaaa tagcctcttg
     2161 gtccaggcta tcaatgatgc tagccaattc gctagcaatc aattcttttg tattcattaa
     2221 gagctccttt ttggactttt ctactatttt aacacaattt taaagaaaga agaaaaaatt
     2281 tttgaaatct cttgtttttt tggtataata tggttataaa tatagttata aatatgcacg
     2341 caagaggatt ttatgagaaa aagagatcgt catcagttaa taaaaaaaat gattactgag
     2401 gagaaattaa gtacacaaaa agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg
     2461 acgcagacaa ccttgtctcg tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat
     2521 gatatggtgt attatgtact agtaaatgag acagaaaaga ttgatttggt ggaatttttg
     2581 tctcatcatt tagaaggtgt tgcaagagca gagtttacct tggtgcttca taccaaattg
     2641 ggagaagcct ctgttttggc aaatattgta gatgtaaaca aggataaatg gattttagga
     2701 acagttgctg gtgccaatac cttattggtt atttgtcgag atcagcacgt tgccaaactc
     2761 atggaagatc gtttgctaga tttgatgaaa gataagtaag gtcttgggag ttgctctcaa
     2821 gacttatttt tgaaaaggag agacagaaaa tggcgataga aaagctatca cccggcatgc
     2881 aacagtatgt ggatattaaa aagcaatatc cagatgcttt tttgctcttt cggatgggtg
     2941 atttttatga attattttat gaggatgcgg tcaatgctgc gcagattctg gaaatttcct
     3001 taacgagtcg caacaagaat gccgacaatc cgatccctat ggcgggtgtt ccctatcatt
     3061 ctgcccaaca gtatatcgat gtcttgattg agcagggtta taaggtggct atcgcagagc
     3121 agatggaaga tcctaaacaa gcagttgggg ttgttaaacg agaggttgtt caggtcatta
     3181 cgccagggac agtggtcgat agcagtaagc cggacagtca gaataatttt ttggtttcca
     3241 tagaccgcga aggcaatcaa tttggcctag cttatatgga tttggtgacg ggtgactttt
     3301 atgtgacagg tcttttggat ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc
     3361 gagaagtggt gttgggttat gacttgtctg aggaagaaga acaaatcctc agccgccaga
     3421 tgaatctggt actctcttat gaaaaagaaa gctttgaaga ccttcattta ttggatttgc
     3481 gattggcaac ggtggagcaa acggcatcta gtaagctgct ccagtatgtt catcggactc
     3541 agatgaggga attgaaccac ctcaaacctg ttatccgcta cgaaattaag gatttcttgc
     3601 agatggatta tgcgaccaag gctagtctgg atttggttga gaatgctcgc tcaggtaaga
     3661 aacaaggcag tcttttctgg cttttggatg aaaccaaaac ggctatgggg atgcgtctct
     3721 tgcgttcttg gattcatcgc cccttgattg ataaggaacg aatcgtccaa cgtcaagaag
     3781 tagtgcaggt ctttctcgac catttctttg agcgtagtga cttgacagac agtctcaagg
     3841 gtgtttatga cattgagcgc ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg
     3901 atctcttgca gttggcgact accttgtcta gtgtgccacg gattcgtgcg attttagaag
     3961 ggatggagca acctactcta gcctatctca tcgcacaact ggatgcaatc cctgagttgg
     4021 agagtttgat tagcgcagcg attgctcctg aagctcctca tgtgattaca gatgggggaa
     4081 ttatccggac tggatttgat gagactttag acaagtatcg ttgcgttctc agagaaggga
     4141 ctagctggat tgctgagatt gaggctaagg agcgagaaaa ctctggtatc agcacgctca
     4201 agattgacta caataaaaag gatggctact attttcatgt gaccaattcg caactgggaa
     4261 atgtgccagc ccactttttc cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg
     4321 aagaattagc ccgtatcgag ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg
     4381 aatacgaaat atttatgcgc attcgtgaag aggtcggcaa gtacatccag cgtttacaag
     4441 ctctagccca aggaattgcg acggttgatg tcttacagag tctggcggtt gtggctgaaa
     4501 cccagcattt gattcgacct gagtttggtg acgattcaca aattgatatc cggaaagggc
     4561 gccatgctgt cgttgaaaag gttatggggg ctcagaccta tattccaaat acgattcaga
     4621 tggcagaaga taccagtatt caactggtta cagggccaaa catgagtggg aagtctacct
     4681 atatgcgtca gttagccatg acggcggtta tggcccagct gggttcctat gttcctgctg
     4741 aaagcgccca tttaccgatt tttgatgcga tttttacccg tatcggagca gcagatgact
     4801 tggtttcggg tcagtcaacc ttcatggtgg agatgatgga ggccaataat gccatttcgc
     4861 atgcgaccaa gaactctctc attctctttg atgaattggg gcgtggaact gcaacttatg
     4921 acgggatggc tcttgctcag tccatcatcg aatatatcca tgagcacatc ggagctaaga
     4981 ccctctttgc gacccactac catgagttga ctagtctgga gtctagttta caacacttgg
     5041 tcaatgtcca cgtggcaact ttggagcagg atgggcaggt caccttcctt cacaagattg
     5101 aaccgggacc agctgataaa tcctacggta tccatgttgc caagattgct ggcttgccag
     5161 cagacctttt agcaagggcg gataagattt tgactcagct agagaatcaa ggaacagaga
     5221 gtcctcctcc catgagacaa actagtgctg tcactgaaca gatttcactc tttgataggg
     5281 cagaagagca tcctatccta gcagaattag ctaaactgga tgtgtataat atgacaccta
     5341 tgcaggttat gaatgtctta gtagagttaa aacagaaact ataaaaccaa gactcactag
     5401 ttaatctagc tgtatcaagg agacttcttt gacaattctc cacttttttg ctagaataac
     5461 atcacacaaa cagaatgaaa aggagctgac gcattgtcgc tcccttttgt ctatttttta
     5521 aggagaaagt atgctgattc agaaaataaa aacctacaag tggcaggccc tggcttcgct
     5581 cctgatgaca ggtttgatgg ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt
     5641 cttaggcgcc ctccttactg ggaaatatga agctatttat agtatcgggg cttggttgat
     5701 tggtgtggcc gtagtcggtc tagttgctgg tggactcaat gttgtcctcg cagcctatat
     5761 tgcccaagga gtttcatccg accttcggga ggatgccttc cgtaaaattc aaaccttttc
     5821 ttatgctgat attgaacaat ttaatgcggg aaatctagtc gttcgaatga caaatgatat
     5881 caaccagatt cagaacgttg tcatgatgac cttccagatt cttttcagac ttcccctctt
     5941 gttcatcggt tcgtttatcc tagcggttca aaccttacct tctctgtggt gggtgattgt
     6001 tctcatggta gtcttgattt ttggtttgac tgctgtcatg atgggaatga tggggcctcg
     6061 ttttgccaag tttcaaaccc ttcttgagcg catcaatgcc attgccaagg aaaatttacg
     6121 tggcgttcgt gtggtcaagt cctttgtcca agaaaaagag caatttgcta agtttacaga
     6181 ggtctcagac gagcttcttg gtcaaaacct ttacattggt tatgcctttt cagtagtgga
     6241 accctttatg atgttggttg gttacggggc ggtcttcctc tctatttggc tggtcgcggg
     6301 aatggttcag tcggatccgt ctgttgttgg ttccatcgct tcttttgtta attacctaag
     6361 ccagattatc tttaccattg ttatggttgg atttttggga aattctgtca gccgtgccat
     6421 gatttccatg cgtcgtattc gagaaattct tgacgcagag ccagctatga ccttcaagga
     6481 tatcccagat gaagagttgg ttggaagcct tagctttgaa aatgtgacct ttacctatcc
     6541 aatggacaat gaaccgatgc tgaaagatgt gagctttact attgaacctg gtcaaatggt
     6601 tggtgtagtt ggagcgactg gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct
     6661 ctttgatcca cagaacgggg ccattaaaat cggtggcaag gatattcgag aagtgagtga
     6721 aggaaccctg cgtaaaacag tttccatcgt tctccaacgt gccattcttt ttagtggaac
     6781 gattgcagat aacttgagac aggggaaggg aaatgctact ctatttgaaa tggagcgcgc
     6841 agccaatatt gcccaggcta gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc
     6901 agttgaagaa cggggaacca atttctctgg tggacaaaaa caaaggatgt cgattgcgcg
     6961 tgggattgtc agcaatccac gtattctgat ttttgacgat tcgacctcag ccttggatgc
     7021 caaatcagag cgcttggtgc aagaagcttt gaataaggac ttgaagggga cgacaaccat
     7081 tattattgct caaaaaatta gctcggttgt ccatgcagac aagatcttgg ttctaaatca
     7141 aggacgattg attggtcaag gcacgcatgc agacttggtt gccaacaatg ccgtttaccg
     7201 tgaaatctat gaaacacaga aatgaaagac aaactataag aaaagtcaat agttttatct
     7261 aaattatttc ttatttcaat ttgatgattt ggcgatgatt ttagagcacg gcaaaaagcc
     7321 cttgaaaaag tccatttttt caaaggtaat cctgtgttga tttcagaaat tacatcactt
     7381 tttgttcgtc aaatggcagc tcttttttag gatataaaac agggttcgga taagtttttt
     7441 tgtaaggtgg atgatggcta cattgtaatg ttttccttat tctaacttag tcttaagata
     7501 ggccttaaaa gcaggtgaaa agcgagggca tgctttggca gcttgtatga gtgcctaccg
     7561 cagatgaggg gaaccccgtt tgatcattct tccagctaaa tcaatctgat ctgactgata
     7621 aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa aggcatgaat
     7681 attttgaatc tcggctaaaa tgaccgcccc taaacgattc ccaatcccag taaccgtcgt
     7741 gatgatcgag ttgaactcag ccatcaagtc attgacacat gtttccgcct tgtcaatgag
     7801 cctcttgtaa tgtttgatgt tttcattaca cgagataaaa cgtttatgcg ttatcaaact
     7861 catgaccaat tgaaacaaaa agctgtggtt agatcctttc ggaaattgtc aagcgattgg
     7921 aggaaatgaa ctaatccaca gcggcttatt ccaagtatac cacttgggct ttggcagtag
     7981 ctaactgcgc taaatataat ataaggagga gtaaaatgaa gacagttcaa tttttttggc
     8041 attattttaa ggtttacaag ttctcatttg tagttgtcat cctgatgatt gttctggcga
     8101 cttttgccca agccctcttt ccagtctttt ctggacaagc ggtgacgcag ctagccaatt
     8161 tagttcaagc ttatcaaaat ggcaatccag aacttgtatg gcaaagccta tcaggaatca
     8221 tggtcaatct tggcctgctg gttttggttc tatttatctc tagtgtaata tacatgtgtc
     8281 tcatgacgcg cgtgattgca gaatcgacca acgagatgcg caaaggcctc tttggtaagc
     8341 ttgctcagtt gacggtttct ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt
     8401 ttaccagtga tttggataat atcctccaag cctttaacga aagcttgatt caggtcatgt
     8461 gcaatattgt tttatacatt ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg
     8521 ctctcatcac cattgccagc accccattgg ctttccttat gctgattttc atcgtgaaaa
     8581 tggcacgcaa atacaccaac ctccagcaga aagaggtagg gaagctcaac gcctatatgg
     8641 atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg aattcaagag gatatgatgg
     8701 caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct
     8761 caggaattct tttccctgtc atgaatggga tgagcctgat taatacagcc atcgtcatct
     8821 ttgctggttc ggctgtactt ttgaatgata agtctattga aacaagtaca gccctaggtt
     8881 tgattgttat gtttgcacaa ttttcacagc agtactacca gcctattatc caagttgcag
     8941 cgagttgggg aagccttcag ttggccttta ctggagctga acgaattcag gaaatgtttg
     9001 atgcagagga ggaaatccga cctgaaaagg ctccaacctt cactaagttg caagaaagtg
     9061 ttgaaatcag tcatatcgat ttttcatact tgcctgataa acctattttg aaagatgtca
     9121 gcatttctgc ccctaaaggc cagatgacag cagttgttgg gccgacaggt tcaggaaaaa
     9181 cgactattat gaacctcatc aatcgctttt atgatgttga tgctggtggt atttattttg
     9241 atggtaaaga cattcgtggc tatgacttag atagtcttag aagcaaggtg ggaattgtat
     9301 tgcaagattc ggtcttgttt agcggaacga ttcgagacaa tatccgattt ggtgtgccag
     9361 atgctagtca ggaaatggtt gaggtagcag caaaagcaac ccacattcac gactatatcg
     9421 aaagtttgcc tgataagtac gatactctta ttgatgatga ccagagcatc ttttcaacag
     9481 ggcagaagca attgatttca atcgctcgaa ccctgatgac agatccagaa gttctcattc
     9541 tcgatgaagc aacttcaaac gtagatacgg tgacagaaag caagattcag catgccatgg
     9601 aggtggttgt agcaggtaga actagtttcg tcattgccca ccgcttgaaa accattctca
     9661 atgcagatca gattattgtc cttaaagatg gagaagtcat tgaacgtggt aaccaccatg
     9721 aacttttgaa gctaggtggc ttttattcag aactctatca caatcaattt gttttcgaat
     9781 gagaaagaag ttgtcctatg tgggcagctt tttcttgtcc ataaaaaatg tttatcacag
     9841 ccttaaaaaa aacatattag acgaaagtca ttttgagtga tatgatagga ctatcgttag
     9901 cattcgaaag gagaggcatc atggctagaa cggttgtagg agttgctgca aatctatgtc
     9961 ccgtagacgc agaaggcaaa atcattcatt catctgtatc ttgtagattc gcagagatca
    10021 ttcgtcaagt cggtggtctc cctttagtca ttcctgttgg tgatgagtca gttgtacgtg
    10081 attatgtgga aatgattgac aaactcattt tgacaggagg ccaaaatgtt catcctcagt
    10141 tttatggaga gaaaaagacc gtcgagagcg atgattacaa tctggtccgt gacgaatttg
    10201 aattggcact cttgaaggaa gcgcttcgtc agaataaacc aattatggca atctgtcgcg
    10261 gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact
    10321 ggcaaggact acctttcggg acatctcact ctattgagac agtagaagga agcgtggtgg
    10381 ctaagctatt tgggaaagaa agtcaggtca attcagtcca tcgtcaaagc attaaagatt
    10441 tggcacccaa tttccgtgta actgctattg attcaagaga ccaaactatt gaagcgattg
    10501 agtctatcga cgagcaccgc attatcggtt tacagtggca tccagagttt ctggttaatg
    10561 aagaagatgg caatttagaa ttatttgagt atttattgaa tgaactgtaa cgattggaac
    10621 atctggtcgt tctttctttt attttttcaa aatttttaga atgtggtatt ttacgcaaac
    10681 gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta
    10741 agcgttatga tagaaaagaa gaaatattgg aggaagaaca tgtcacatat taaatttgat
    10801 tattcaaaag ttttagacaa atttgttgca ccacatgaag tggaatacat gcaatcacaa
    10861 gtaacagcag cagatgaatt gatccgtaaa ggaactggtg ctggtagcga cttcttggga
    10921 tggttggacc ttcctgaaaa atacgaccgc gaagaatttg accgcatctt gaaagctgct
    10981 gagcaaatca agtcagacag cgatgttttg gttgtgatcg gtattggtgg atcttacctt
    11041 ggtgcaaaag cagcaatcga cttcttgaat caccattttg ctaacttgca aacaaaagaa
    11101 gaacgcaaag ctccacaaat cctttacgca ggaaactcaa tctcatctac ttaccttgct
    11161 gacttggtag agtatgttgc agacaaagac ttctcagtaa acgtaatttc taaatcaggt
    11221 acaacaactg aaccagcgat tgctttccgt gtctttaaag aactcttggt taagaaatac
    11281 ggtcaagaag aagctaacaa acgtatctat gcaacaactg accgccaaaa gggtgctgtt
    11341 aaggttgaag cagacgctaa cggttgggaa acatttgttg ttccagatga tatcggtgga
    11401 cgcttctcag tattgacagc cgttggtttg cttccaatcg cagcatcagg agctgacatc
    11461 aaagctctta tggaaggtgc gaatgcagct cgcaaagact acacttcaga caaaatctct
    11521 gaaaacgaag cttaccaata cgcagctgtt cgtaacatcc tttatcgtaa aggctatgca
    11581 actgagatct tggtaaacta tgagccatca cttcaatact tctcagaatg gtggaaacaa
    11641 ttggctggtg aatcagaagg aaaagaccaa aaaggtatct acccaacttc agccaacttc
    11701 tcaactgact tgcactcact tggtcaattt atccaagaag gaactcgtat catgtttgaa
    11761 acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta ttcctacttt ggaagaagac
    11821 cttgacggac ttggttacct tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact
    11881 gacggtgttc ttcttgccca cacagatggt gatgtaccaa acatgtatgt gactcttcca
    11941 gagcaagacg ctttcactct tggttacact atctacttct tcgaattggc aattgccctt
    12001 tcaggttact tgaatgctat caacccattt gaccaaccag gtgttgaagc ttataaacgt
    12061 aacatgtttg cccttcttgg aaaaccagga tttgaagaat tgagcaaaga acttaacgca
    12121 cgtctataat agaagaaaag agtggtttac ccactctttt tactctcttt atccatagaa
    12181 attggactca gtcaagactt gtgatataat atagaaagca aaaaggcaga tgcctagata
    12241 ataggagaaa ctatgtcaaa agatatccgc gtacgttacg caccaagtcc aacaggacta
    12301 ctacacatcg gaaatgctcg tacagcattg tttaattact tgtatgcgcg ccatcatggt
    12361 ggaacatttc tcatccgtat cgaagatact gaccgtaaac gccatgtcga ggatggtgaa
    12421 cgttcacaac ttgaaaacct tcgctggtta ggcatggatt gggatgaaag tccagaatca
    12481 catgagaatt atcgccagtc tgagcgttta gacttgtatc aaaaatacat tgaccaacta
    12541 ttagctgaag gaaaagccta taaatcttac gttacagaag aagagttggc agctgaacgc
    12601 gaacgccaag aagtagctgg cgaaacacca cgctacatca atgaatacct tggtatgagt
    12661 gaagaagaaa aagcagctta catcgcagaa cgtgaagcag cagggatcat cccaactgtt
    12721 cgtttggctg tcaatgagtc aggtatctac aagtggcatg atatggtcaa aggcgatatc
    12781 gaatttgaag gtggcaatat cggtggtgac tgggttatcc aaaagaaaga cggttaccca
    12841 acttacaact ttgccgttgc catcgatgac cacgatatgc aaatctctca tgttatccgt
    12901 ggagatgacc atattgctaa tacaccaaaa cagcttatgg tctatgaatc tcttggttgg
    12961 gaagctccag agttcggtca catgaccttg attatcaact ctgagactgg taagaagtta
    13021 tctaaacgtg atactaatac acttcaattt atcgaagatt accgaaagaa aggttacctt
    13081 ccagaagcag tctttaactt tattgctctt cttggttgga acccaggtgg tgaagatgag
    13141 attttctctc gtgaagaact cattaaactt tttgatgaaa accgcctcag caagtcacca
    13201 gcagcctttg atcagaaaaa actagactgg atgagcaatg attatatcaa gaatgcagac
    13261 cttgaaacca tctttgaaat ggcaaaacca ttcttagagg aagcaggccg tttgactgac
    13321 aaggctgaaa aattagttga gctctataaa ccacaaatga aatcagtaga tgagattatc
    13381 ccattgacag atcttttctt ctcagatttc ccagaattga cagaagcaga gcgcgaagtc
    13441 atgacgggtg aaacagttcc aacagttctt gaagcattca aagcaaaact tgaagcgatg
    13501 acagatgata aatttgtgac agaaaatatc ttcccacaaa ttaaagcagt tcaaaaagaa
    13561 acaggtatta aagggaaaaa tcttttcatg cctattcgta tcgcagtttc aggcgaaatg
    13621 catgggccag aattaccaga tacaattttc ttgcttggac gtgaaaaatc aattcagcat
    13681 atcgaaaaca tgctaaaaga aatctctaaa taaagaggat acaataatgg acatctggga
    13741 aaagatgtac gaagaagcac agaaactata caatccacat gaagtatcag actttgttta
    13801 tgccaatcat gttgtagctg cagtagaagc agaagatgga caaatattta caggattctg
    13861 tatggaggga acctgtggtg ttttccatct ctgcgcagaa cgggcggccc tcttcaatat
    13921 gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta gcctttcgag acaaaccacc
    13981 ttatggtgga agttcagcca tgccttgcgg tgcttgtaga gaattccttt tagagcttaa
    14041 tgctgaaaat aaagatgcag aattcatgat ggactataat ataagaaaaa cagttaaagt
    14101 cgcagaacta atcccttatt ggtggggaga agaacgtgct tctaagttta atgagcgata
    14161 gaagagtcag tataattttg gctcttttta ctataagttg aaaaaata
//
LOCUS       DAVBOM010000053        13224 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBOM010000053 DAVBOM010000000
VERSION     DAVBOM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13224
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.053"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(352..1575)
                     /locus_tag="VQ878_001738"
     CDS             complement(352..1575)
                     /locus_tag="VQ878_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3096043.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1743..3065
                     /locus_tag="VQ878_001739"
     CDS             1743..3065
                     /locus_tag="VQ878_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3096044.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGGIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTIENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            3067..4953
                     /locus_tag="VQ878_001740"
     CDS             3067..4953
                     /locus_tag="VQ878_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET3096045.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            5121..5465
                     /locus_tag="VQ878_001741"
     CDS             5121..5465
                     /locus_tag="VQ878_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3096046.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5475..6887
                     /gene="lacG"
                     /locus_tag="VQ878_001742"
     CDS             5475..6887
                     /gene="lacG"
                     /locus_tag="VQ878_001742"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3096047.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVREFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6957..8636
                     /locus_tag="VQ878_001743"
     CDS             6957..8636
                     /locus_tag="VQ878_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3096048.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPCEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(8762..10201)
                     /locus_tag="VQ878_001744"
     CDS             complement(8762..10201)
                     /locus_tag="VQ878_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3096049.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10205..11554)
                     /gene="trkA"
                     /locus_tag="VQ878_001745"
     CDS             complement(10205..11554)
                     /gene="trkA"
                     /locus_tag="VQ878_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET3096050.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVNRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11742..12590
                     /locus_tag="VQ878_001746"
     CDS             11742..12590
                     /locus_tag="VQ878_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET3096051.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12605..13153
                     /locus_tag="VQ878_001747"
     CDS             12605..13153
                     /locus_tag="VQ878_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET3096052.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         4045 a         2122 c         2821 g         4236 t
ORIGIN      
        1 caacctcaaa acagtgtttt gagcagcctg cagctagctt cctagtttgc tctttgattt
       61 tcattgagta taaggagaat tgtaaaaaca aaaatgggga tttcatataa agtttattct
      121 aggagtatgt atcttgaata aaaattgtta tttaagttct gggggttatg atgaatgttt
      181 ttataataat aaaatgcagc tagaagaaaa gttattttaa tataaatcac tcaacataga
      241 gagaaggcgg tttcctatat ggaagtcgtc ttgttttcat attgtctaaa tacgagatat
      301 ttactacagg ttatagttga tttaaacagg tctatagatt tctaatatat attaaggtga
      361 aataatatct tgtaatacat tgctatgctc tatgaaaaaa gcaacgatag ctaatgcaca
      421 agctcctata cttccacgat gtttgttgta aggtaaaatt tcaatttcta tattacgagt
      481 aaagggaacg aagtggagct ggtcttggat tttatccctg acttcatgag tgaaaggttg
      541 ataattaagc aattgactgt tgatatagat tttatcagca ggattgatga ggagaagatt
      601 tgcaatagaa gtggctaata aattgactcc tttatcaatt tgttgacgta aagcggagtc
      661 gcctaaatta taagccgtta aaagggtgtc taaatgaatg tctttttcag tctttacaag
      721 gctttttagt acagttagtt gggaattttt aaataataat tgggcgtgtt tgattaacca
      781 agcatccgaa atatatgttt gtaaacaacc tttttttccg cattcacaat attgcccatt
      841 caattcgaca atggtgtgtc caatttctcc gatataagga tttttagagg ctcctatttt
      901 ttcttttgtg aaaaaggaag tgtaaatacc taatccagcg tgtaggaaaa taaagttatc
      961 gggggtattg tgtggattaa aaaggtattg tcctatagcc atacaatcga tattattttt
     1021 tacaataaaa ggaaaattga atcttttaat tacatttaat aaattaaaag attcccatat
     1081 ggggttgttt gtaatgatac ttccggagtc tttgttataa tgtccaggta ttgataagcc
     1141 aaatccaagt aattttgttt ccaaagggac gtactctata gctgttttta tcatattggt
     1201 aatggtggaa ttgatttctg aaataggata atcttcattc aaaatttctg tctcgaaaag
     1261 agttttccct tgtaagtcac atagactgag aaagatacct aggacgttta tttcaatacc
     1321 tccaacaaca tacggaatat tatctgtgat agaaatagtt tttctacgtc ttccagatcc
     1381 ggaaaactcg ctaaattcat caccagtttc gtatatgagg gactgttcgc ttagctcttt
     1441 tatgatgtta gtcgttgttg ctggagtaag tcctgtttca ttaacaatat ctgtacggga
     1501 tgttgctgga tttcgatata gaaactccag tatagtggct ctattttgta aaaaggctga
     1561 ttgttttgta atcatttgtt tcctcctttg gtttatttta tattaaacat aagaaaaaat
     1621 caattaaaat tattattcta tacaaagaaa aaaatattgt aaaaacaaca aaaaatatat
     1681 tgacaacgct ttctgttagt ggtatattta atttataaaa aataaaaaaa ggagttccgg
     1741 tgatgaacaa tattttagcg tttttagaaa caaaagtcgc tccgtttggt gaaaaagttg
     1801 gcaaccaacg gcatttgaaa gctattcgtg aaggatttat gatggcaatg cctttgattt
     1861 tagtcggatc tttatttctt attctaatca gttggcctca agaggatttt acaaattggc
     1921 tgaatagtgt tggattgcta agtatcttga caactatgaa tcagtcaaca gtagcgatta
     1981 tctccttggt cgcttgtttc ggtattgcct acaggttgtc ggaaggatat ggtacagatg
     2041 gtccgtcggc agggatcata gccttatcca gttttgtatt gatggcacct cgtttttcga
     2101 gtatggttta tgataaaaat ggggagcagg tcaagcagtt atttggcggc gcaataccat
     2161 tttctagcct gaatgcatct tctttgttta tggcgattac tattggattg gttacagcag
     2221 agatttatcg tatgtttatc cagcgcggaa ttacgataaa aatgccaagt ggtgtcccag
     2281 atgtggtaag taaatcattt tcagctcttt tacctggctt tactactttt gttttgtggg
     2341 ctctggtctt aaaaggtctt gaagcggcag gagttgcagg aggtctcaac ggactcctag
     2401 gtggaattgt tggaacaccg cttaagttaa ttgcaggaac gcttccaggt atgattctat
     2461 gtgttattgt aaactcattc ttttggttct gtggagttaa tgggggacaa gttttaaatg
     2521 cttttgtaga tccagtttgg ttacaattta ctatagaaaa ccaagaagct gtggctgcag
     2581 gacaaacact ccaacacatt attacattac cgtttaaaga tttatttgta tttattggtg
     2641 gcggtggagc gactattggt cttgcgattt gtctcttcct atttagtaag agtcgtgcga
     2701 ataaaacatt aggtaagcta gctattatac cgtctatttt taatatcaat acagctattc
     2761 tatttacgtt tccaacagtt ttaaatccga ttatgctgat tccgtttatt gctactccta
     2821 caatcaatgc cttgattacc tatgtatcaa tggctgtagg attagtaccc tatacaacag
     2881 gtgtaatcct tccgtggaca atgccaccga ttataggagg cttccttgca acaggggcta
     2941 gttggcgagg agctctatta caagttgttt tgattttggt ttctgtagca atttattatc
     3001 cattcttcaa aattgcagat aaacgcaatc ttgaaaaaga aaaagctact gttggaggga
     3061 aataagatgg ttatcagagt atttgatcaa cagaaaaata cttattctag ctttgcctta
     3121 gaggaattaa gttactatat gaatcgggtc tttaagacta acatagagct tgtcgaggag
     3181 aaggaagcgg atatttttgt aggattagtc aataaagagg acagaaaaga ccatgttctt
     3241 atctcattag acaagggtaa gggaagaatt gagtctaata caattgtagg tttacttatt
     3301 ggaatttacc gaatgtttca tgaatttggg gttgtgtata ctagaccagg gcgcagacat
     3361 gactttgttc cagagttacg atttgaagat tttttagata aacagctatc tatagatgaa
     3421 acagccagtt actatcatag gggagtatgt atagagggag cggattcatt tgaaaatata
     3481 ctagatttca ttgattggct acctaagatt gggatgaaca gttttttcat ccagtttgaa
     3541 aatccttact cttttttgaa acgttggtat gaacatgaat ttaatccata tctaaataaa
     3601 gaacaatttt caaatgaatt agtacaagaa ttgagtgata ggttggataa agaattgcaa
     3661 aaaagaggtc ttattcatca tcgtgttggt catggatgga caggtgaagt tttaggttac
     3721 tcttcaaaat ttggctggga atcaggtctt agtatttcag aggagaagaa accctatgtc
     3781 gctgaaataa acgggaaacg agaattgttt aatacggctc cgattttaac cagcctggat
     3841 ttttcaaatc cagatgtagc tgataagatg gtagaaatta tcaaggatta tgccaagaaa
     3901 agacctgatg ttaactactt acatgtatgg ttgtcggatg ctcgtaataa tatttgtgaa
     3961 tgcgaaaact gtagacaaga attggtttcg gatcagtata ttcgtattct caatcaattg
     4021 gatagggctt taacgagtga gggattagat acaaagattt gttttctgct ttaccatgag
     4081 ttgctatggg cgcctcagaa agaaaaatta gataatcctg aacgctttac catgatgttt
     4141 gcaccgatta caagaacatt tgaaatgagt tatgcagatg tagattttga caattccata
     4201 cctacgccta aaccttatct gcgtaataaa attatacttc cgaattctct tgaggaaaat
     4261 ttatcttatc tttttgagtg gcaaaaaaca tttaaaggag atagtttcgt atatgactat
     4321 cctttagggc gtgctcatta tggcgattta ggctatatga aaattagtca aaccatttac
     4381 agagatgtat cttatctttc taacctacat ttgaacggtt acatttcgtg tcaagaatta
     4441 cgtgccggat tccctcataa ttttcctaat tatgttatgg gggaaatgct ctggaagaag
     4501 acaagaagtt atgaagaatt gattgaagaa tacttttctg ctttgtatgg gtcaaattgg
     4561 cagtctgttg ttgaatattt agaaaaatta tccagttatt cctcatgtga ttattttaat
     4621 gcaattggca gtcgtcaaaa tgatgtttta gcgaatcatt attatatagc ttacaatcta
     4681 gctgataatt ttttgccaat tattgaggaa aatatttcta agttattaaa tagtcaaaag
     4741 gatgaatgga aacagctcag ttatcatcgt gaatatgttg ttaagatggc gaaggcttta
     4801 tatcttcaag caaccggaaa aacaaggcaa gctcaagatg aatggagaaa tgtgttgaat
     4861 tatatccgtg ggcacgaact gctattccaa tctaatttgg atgtttatcg tgtaattgaa
     4921 gtagcaaaaa attacgctgg tttccactta taaatcataa gtatagaaaa tgaaccaagg
     4981 tattcagaga agattgatcc taaatattat gaaatttaag gatttttaag atatttaggg
     5041 tcgactttct atttatatcg tagcgaagtc attttaataa tgatgtgtaa aagatggatc
     5101 aagattgagg aggaagaaag atgaaatcaa aagaagaaat aaatatgctt ggttttacaa
     5161 ttgtcgctta cgcaggagat gcaaggtcag atttgatgga tgctttggcg tttgcgagag
     5221 atggatattt tgaacaggca agagaattgg ttgagtctgc aaacgactca atagtgtctg
     5281 cccatcgaga acagactaat ttattagcgg aggaggcatc tggagataat tttgaagtga
     5341 gttttatcat gattcatggt caagatacct tgatgacaac gatgctattg tatgatcagg
     5401 tcaagttttt tattgatgaa tatgaacgaa ttcgaaagat tgaagaacat attggtttgc
     5461 aatgaggatt agtcatggaa aatttacagg ttaaagcctt accgaaggag tttttattag
     5521 gagctgctac cgctgcttat caagtagagg gtgcaactag ggtagatggc aaaggaacaa
     5581 atatgtggga tgtttatttg caagaaaaca gtccgttttt accagatccg gctagtgatt
     5641 tttattatcg ttacgaagag gatatagctt tggcggcaga acatggtttg caggctttgc
     5701 gtttatctat ttcttgggtt cgtatatttc ctgatataga tggggagcct aatatattag
     5761 ctgttcgtta ttaccataga gtctttcagt cttgcttaaa acataatgtg attccgtttg
     5821 tttctttaca tcattttgat tcgcctcaga aaatgttaga aacaggggat tggttgaata
     5881 gagagaatat tgatcgtttc atacgatatg ctcgcttttg tttccaagaa tttacagaag
     5941 tcaagcattg gtttacaatc aatgaactga tgtctcttgc tgcaggtcaa tatataggag
     6001 gtcagtttcc tccaaatcat cattttcaat tatctgaagc aattcaagcg aatcataata
     6061 tgttgttggc gcatgctctt gcagtccgcg aatttcatca attagggatt gagggaaaga
     6121 taggttgtat tcatgcttta aagccaggct atcctattga tgggcaaaaa gaaaatattt
     6181 tggcagctaa acggtatgat gtttataata ataaatttct attagatgga acttttttgg
     6241 gctactacag tgaggacacg ctttttcact tgaatcaaat attggaagct aataattcta
     6301 gctttattat tgaagatggt gatttagaaa ttatgaagag agctgcagct cttaatacga
     6361 tgtttgggat gaattattat cgttcagaat ttattcgtga atacaaaggt gaaaatagac
     6421 aagaatttaa ttcaacagga ataaaaggac agtcttcttt taaattaaat gctctaggtg
     6481 aatttgtaaa aaaacctggt attccgacaa cagattggga ttggaatatt tatcctcaag
     6541 ggttatttga tatgttgctt cgtatcaaag aagaatatcc tcaacatccg gtcatttatt
     6601 taactgaaaa tggtacagcc cttaaagaag ttaagccaga gggcgagaat gatattattg
     6661 atgacagtaa gagaatccgt tatattgagc aacatttaca caaagtttta gaggctcgag
     6721 atagaggagt caatattcaa ggctatttta tatggtcttt gcaagatcaa ttttcttggg
     6781 cgaatggcta caataagcga tatggtcttt tctttgttga ttatgaaaca cagaagagat
     6841 atattaagaa aagtgctctt tgggtaaaag ggctaaaacg gaattaaggt tagcgatttg
     6901 actgatgttt aatatatttt aactatgagc ttaaattttt tacaggagga gtttttatgg
     6961 ataagttagt cgctgccatt gaaaagcaac aagggaaatt tgaaaaaatt tctactaata
     7021 attatatgat ggctattaaa gatggattta ttgctactat gcctttaatt atgttttcaa
     7081 gctttttgat gattattatt atgattccta aaaatttcgg agtagagtta ccgagtccag
     7141 ctattgcctg gatgaggaaa gtgtatatgc taaccatggg agttttgggt attattgttt
     7201 cagggacagt tgcaaagtca ttggctggaa atgttaatag aaaaatgcct cctggaaagg
     7261 taataaatga tacttctgca atgttggcgg ccatatgtgg ctatcttgta ttaactgtaa
     7321 cgcttgtagt tgatgagaaa acgggatcta caagtttgtc gacaaactat ttaggatctc
     7381 aaggattgat aacttcgttt gtcagtgcct ttattactgt aaatgtttac cgattctgta
     7441 ttaagcgaga cattactatt catttaccta aggaagttcc tggggctata tcacaagctt
     7501 ttagagatat ttttcctttt tcttttgttt tacttattag tggtttgtta gatattgtat
     7561 ctcgttttag tttagatgtt ccttttgccc aagtatttca acaactattg actcctattt
     7621 ttaagggggc agaatcatat cctgctatga tgttgatttg gtttatgtgt gctttgcttt
     7681 ggtttgttgg aattcatgga ccatctattg tcttacctgc tgttacagct ttacaactga
     7741 gcaatatgga agagaatgct caacttcttg caaatgggca gttcccttat cattctttaa
     7801 cacctaattt cgggaattat atcgctgcta ttggaggaac gggggctacc tttgttgtac
     7861 catttatttt gattttcttt atgcggtcta aacaattaaa atcggtaggt aaagctacaa
     7921 ttactcctgt tttatttgcg gtaaatgaac ctcttctatt tggtatgcct gttattttga
     7981 atccctatct ttttgtacct tttttgatga ctccaccagt gaatgtattt ctaggaaagg
     8041 tatttattga tttctttgga atgaatggat tttatatcca gttaccttgg gcctttcctg
     8101 gtcccttggg attgttaatt ggaacgaatt ttcaacttat ctcctttgta tttttatctt
     8161 tgatgttagt tgtcgacata ttgatttatt tgccattctg tagagcgtat gatagacagt
     8221 tactggtgaa agaagatatt gcaagctcaa atgatattat tttagaggag gatacaagtg
     8281 aaataatgcc ttgtgagata gatgtaataa aaagtaagga gttgaaagta ctggttcttt
     8341 gtgcagggtc tggaacaagt gcgcaattag ccaatgcaat taacgagggc gctcaattag
     8401 cagaagttag agtgattgcg aattcaggag cgtacggagc tcattatgat attatgggtg
     8461 tttatgattt aattattctg gccccacaag ttcggagtta ttatagagag atgaaggtgg
     8521 atgcagaaag attaggtatt cagatagttg ctaccagagg aatggaatat attcatttaa
     8581 caaagagtcc aagtaaagcc ttacaatttg tattggagca ttaccaagct gtgtagtaag
     8641 tttttccatc ttttatttga gtaaagattt tgcttacaga taggcttgga tttaaaaacg
     8701 ttcccccttt tttaatataa gaatccctct ttcacaattg taaaaagagg gattttgtat
     8761 tttatctctt agaccaagtt ctcttcataa agagaaggag gattgggtaa atctccaagc
     8821 gccctgcaat cattgcaaag gataggagaa tttttgagat gggactaaag attgagaaac
     8881 tagaagtggt tcctagaata ggcccgatat tattgaaaca gctaaagaca gcgctggtca
     8941 cgaccagaaa atcattgcta tctaggctga caataaagat aagcgctagc aaaatcatag
     9001 catagatgac aaagtacttg agaatcttat gctgggtatc tttgtcaatc accgttttat
     9061 taacatggag ggtcaaaaca cggtggggcg ataggattga caaaatttgg tttttggcaa
     9121 tttttgaaag gatgaggcct cgaataatct tgagtccacc tgcagttgat ccagcagagc
     9181 caccgattgc catgaggaaa aggaggataa actgggagaa gaggggccag ttggtaatat
     9241 ctccatatcc aaaaccagtt gttgtaatga tgttggaaac ctggaagaag gtcatttcaa
     9301 agctctttga aaaccctggg tagaggtaga gggtgttgag gctaatcaag cctgtagaaa
     9361 ccagtacaat gaccaagtaa gcccgaagtt cttcgtcacc aaagaaggcc ttgatgcgac
     9421 ggagcatgag gtagtagtag aggttgaaat ttaccccaaa aaccagaact ccgatactga
     9481 ccagataggt aatcagtgag ctgccatagt gggcaattcc gtcgttatag acggtaaagc
     9541 ctccagttcc cgctgtcccc atagcaatga caaaactatc gtagagaggc ataccagcta
     9601 gataatagat gatgacaaag agggagaaga gagctagata aaggagatag agaatctggg
     9661 cagtgttttt tagtttggat acaaccttgc caaaaacagg acctggaacc tcagccttca
     9721 tcacctctag gtggctattt ttggcattgt ccataatagc aagtgcaaaa acaagcactc
     9781 ccatccctcc aatcaagtgg gtaaaacttc gccagaagag gagggaacgg ctgagaaccg
     9841 aaatgtcgtt caaaatactt gctccagtag ttgtaaaccc agaactaatt tcaaaaaagg
     9901 catcaataac gctagggatt tgcccagaaa agacaaaggg gagaccacca aagaaagacc
     9961 aaaggatcca acagagggca acgatcaaga ctccctcctt ggcataaatc cgttgatttt
    10021 ttggcttctg taaactccct gaaccgccta acaatacgag aatccctatg gtcgaaaaga
    10081 gggctgtaaa gacttggctc gattcacggt aatagacagc gatagccaca ggaaccaaga
    10141 ggagaacagc ttcaatcaaa agtaactttg aaaggaggta acgaatcata cttttattca
    10201 tttcttacct cgcaatcaag tcataaatct tggtgatgtt tggcaacaag gttgttacta
    10261 ggagcttgtc tccaacttcc aacatatcct ccccagttgg gaaaatagtc ttgccctttc
    10321 gaataatggc tgcaataaga accccttttt tcaatttcag ttgagaaaga ggtttggcag
    10381 tcattttatt ggcttccttg atatggaatt gcagggtttc aatttggcca ttggctagat
    10441 ggtgcatggc ttgaaggtct gaatactggg cattaactcg accacgaata aagtgcataa
    10501 tcgtatctac agcgatgctt ttaggtgtga tgatacttga aaaatcaggc gcattgataa
    10561 tctcgaggag actggtacga ttgaccttag taatattttt ctgtacacct accctgtcaa
    10621 ggaacataga tgtaatcaga ttttcctcat cgacacctgt tagagtcgca acggcatcat
    10681 agtgttgagc actttcttcc agcaggatat cttttgcggt tccatctcct tgaacgatgt
    10741 agagatttgg gaatttctcg ctaaagaagc tggcgatttc aggattgatt tcaatgactt
    10801 ttgtatcgat acgactatct ttgagaatac caagtagata ataggcaatt ctacctgccc
    10861 caacgatgag aaggctcttc acggcgcgtg atttaaaata attatggaag agtatcatat
    10921 cgacacggtt accagtgaca aagattctat ctttatcctg tacagtcatg tcaccgcttg
    10981 gaatgataat ttgatgatcc ctctctatcg cacagacaat gacattacca aattttttac
    11041 gaaaatcaga aatgggcatt tggcaaagac cgctggtgga cttgacgaca aattccatga
    11101 ggctaacgcg tccaccagca aagcgttcga cagacagggc gttggggaag tcaatgatat
    11161 tcgcgatagc gcgggcagcc aagagctcag gattaacgat aagagaaaaa ccgagaatat
    11221 tcttttcctt gaaataagag ttagaatatt cagggttccg cacccgaacg atagtttctt
    11281 tagctcccat tttcttggct agaactgctg caatcatgtt gacttcatcg tgctcagtca
    11341 gggcgataaa gatatcacaa tcttggacgc tggcttgctc aagaatggca aaatcggccc
    11401 cgttaccaag gataccaatg atatcaaagc gattgacaat atgattgaga acagcttcgt
    11461 cttgctcaat cagcaaaaca tcatgctttt ctgcaaccaa ggagcgacag agggcaaaac
    11521 caacttttcc ccctccgaca aggataattt tcataataaa acctactttt tcatgatgta
    11581 actatcatac cctttttcaa gaaaaaatgc acctactagc taataacaag agcttttagt
    11641 gaaaattcgc tataaggtaa aactataccc taaccaattg aaatagctat tagcgacttt
    11701 ctctgaaata tggtatgata aaggatatac aaggagataa aatgaataat aatttactgg
    11761 tattacaatc agactttggt ctggttgatg gtgcggtatc ggctatgatt ggagtggctt
    11821 tagaagagtc tccaacctta aaaatccatc acttgacgca cgatatcacg ccttataata
    11881 tttttgaggg gagctatcgt ctctttcaga cggtggatta ctggcctgag ggaacgacgt
    11941 ttgtatcggt tgtcgatcca ggtgtcggtt cgaaacgtaa gagtgtagtt gccaagactg
    12001 caaaaaatca atacattgtc acgccagata atgggacgct ttcctttatc aagaaacacg
    12061 ttggcattgt agccattcgt gagatttctg aggtggccaa taggcgtcaa aacacagagc
    12121 attcttatac cttccacggt cgtgatgtct atgcctatac tggtgctaaa ctggccagtg
    12181 gtcacattac ttttgaggaa gtagggccag agctcagtgt ggaacagatt gtagagcttc
    12241 cagtcgtagc gaccatcata gaagatcatc tggtgaaggg agccattgat attctggatg
    12301 tgcgtttcgg ttcgctttgg acctctatca cacgggaaga attttacaag ctggaaccag
    12361 aatttggtga tcgttttgaa gtgaccatct atcatgctga tatgctggtc tatcaaaatc
    12421 aggttgtcta tggcaaatca tttgcagatg tgagaattgg gcaacccatc ctttacatca
    12481 actctctcta tcgtttaggt ttggctatca accaaggttc ctttgccaag gcctataatg
    12541 taggtgtcgg ttcatcttgg accattgaaa taaagaaaat agaaggataa aataggagaa
    12601 tagtatggaa atcaaattta caattaaaca agttgttgct gtcggaattg gcgctgccct
    12661 ctttgtcgtc atcgggatga tcaacattcc aacccctgtt ccaaatacaa gcatccagct
    12721 tcagtatgcg gtacaagcgc tactttctat tatttttgga ccgattatcg gtttgcttgt
    12781 cgggttgatt ggtcatgcaa tcaaggactc tcttgctggt tatggtctat ggtggacttg
    12841 gattatcgct agcggacttt ttggtctagt tgtgggactt tttagaaagt acgttcgagt
    12901 gatcaatggt gtttttgact ggaaagatat tcttattttt aacctcattc aactacttgc
    12961 aaatgccctt gtttggggtg tcttggcacc acttggagat gttgtgattt atcaagaagc
    13021 ggcagaaaaa gtatttgcac aagggattgt tgcgggaatt gccaatggtg tatctgtagc
    13081 tattgcagga actcttctct tacttgccta tgcaggaacc caaactcgtg caggaagttt
    13141 gaaaaaggac taatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg
    13201 ctcaaaacag tgttttgaga ttgt
//
LOCUS       DAVBOM010000054        13176 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBOM010000054 DAVBOM010000000
VERSION     DAVBOM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.054"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            276..890
                     /locus_tag="VQ878_001748"
     CDS             276..890
                     /locus_tag="VQ878_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET3096053.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAILRLVF"
     gene            994..1824
                     /locus_tag="VQ878_001749"
     CDS             994..1824
                     /locus_tag="VQ878_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3096054.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1978..2832
                     /locus_tag="VQ878_001750"
     CDS             1978..2832
                     /locus_tag="VQ878_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3096055.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2932..4305
                     /locus_tag="VQ878_001751"
     CDS             2932..4305
                     /locus_tag="VQ878_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET3096056.1"
                     /translation="MFFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLCGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4298..5359
                     /locus_tag="VQ878_001752"
     CDS             4298..5359
                     /locus_tag="VQ878_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET3096057.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5361..6053
                     /locus_tag="VQ878_001753"
     CDS             5361..6053
                     /locus_tag="VQ878_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3096058.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6083..6652)
                     /locus_tag="VQ878_001754"
     CDS             complement(6083..6652)
                     /locus_tag="VQ878_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3096059.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6787..7401
                     /locus_tag="VQ878_001755"
     CDS             6787..7401
                     /locus_tag="VQ878_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3096060.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7403..9049
                     /locus_tag="VQ878_001756"
     CDS             7403..9049
                     /locus_tag="VQ878_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3096061.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGNTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9061..10347
                     /locus_tag="VQ878_001757"
     CDS             9061..10347
                     /locus_tag="VQ878_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3096062.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10399..10932
                     /locus_tag="VQ878_001758"
     CDS             10399..10932
                     /locus_tag="VQ878_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3096063.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRVAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ878_001759"
     CDS             11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ878_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET3096064.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHLYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11773..13035)
                     /locus_tag="VQ878_001760"
     CDS             complement(11773..13035)
                     /locus_tag="VQ878_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET3096065.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3901 a         2452 c         3007 g         3816 t
ORIGIN      
        1 tatcttattt caatctgcta tataatagtc catgctatgg ctggattctt ttcagtctac
       61 ttatactctt cgaaactctc ttcaaaccac gtcagcttca ccttgccgta gtacggttac
      121 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagcaacct gcggctagtt
      181 tcctagtttg ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga
      241 aagaaaaagg attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca
      301 gtatcggcct ggcctgtggg actatcggtg cgccctatgt gacacctgtt gagatgggct
      361 tgatgagtct ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg
      421 ttcaagctcc tgtggcagct attgctatga cggtttttct aatcaacttg cgtctctttt
      481 tgttgagttt acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta
      541 tgtctagtat cttgacagat gagacctatg gcgttttgat gggtgaattg gcccatacag
      601 acaaggtaaa tcctatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg
      661 tggggacagt agtcggaacg gctctgggtg gcctgctacc aaatccagaa atctttgcct
      721 tgattctttc aagcgtagtg acaggtaagg ttgggagcct tcctcaaatt aaatggctag
      781 acttcttagc cgtctttcca acagcttggg tagcctttcg ctaccgcaat ctagtcggaa
      841 cagttctctt tggagtggtc ttgattgcca tcttgcgttt ggtcttttaa attacccata
      901 aaaaaaactt atcacagaga tagatatcat ataatggcgt aaatgctctt tttctgttaa
      961 gattataagg tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct
     1021 cttgctgccc taggacttgt tgctgcaggt gtgcttgcgg cttgctcagg gggtgctaag
     1081 aaagaaggag aagcagctag caagaaagaa atcatcgttg caaccaatgg atcaccaagg
     1141 ccatttatct atgaagaaaa tggcgaattg actggttacg agattgaagt cgttcgcgct
     1201 atctttaaag attctgacaa atatgatgtc aagtttgaaa agacagaatg gtcaggtgtc
     1261 tttgctggtc ttgacgctga ccgttacaat atggctgtca acaatcttag ctacactaaa
     1321 gaacgtgcgg agaaatacct ctatgccgca ccaattgccc aaaatcctaa tgtccttgtc
     1381 gtgaagaaag atgactctag tatcaagtct ctcgatgata tcggtggaaa atcgacggaa
     1441 gtcgttcaag ccactacatc agctaagcag ttagaagcat acaatgctga acacacggac
     1501 aacccaacta tccttaacta tactaaggca gacttccaac aaatcatggt acgtttgagc
     1561 gatggacaat ttgactataa gatttttgat aaaatcggtg ttgaaacagt gatcaagaac
     1621 caaggtttgg acaacttgaa agttatcgaa cttccaagcg accaacaacc gtacgtttac
     1681 ccacttcttg ctcaaggtca agatgagttg aaatcatttg tagacaaacg catcaaagaa
     1741 ctttataaag atggaactct tgaaaaattg tctaaacaat tcttcggaga cacttatcta
     1801 ccggcagaag ctgatattaa ataatttctt gaaatcatcc attctgagta aggtgggtgg
     1861 tttctcagtt tttagggata tagttttaaa ctatatatct gactatctaa taacaatttg
     1921 tgaaatcaaa caaattgtga gatactagta cggtattatt tttaaggaga aagaatcatg
     1981 aaaatcaaaa aatggcttgg tctagcagcc cttgctacag tcgcaggttt ggctcttgca
     2041 gcttgcggaa actcagaaaa gaaagcagac aatgcaacaa ctatcaaaat cgcaactgtt
     2101 aaccgtagcg gttctgaaga aaaacgttgg gacaaaatcc aagaattggt taaaaaagac
     2161 ggaattacct tggaatttac agagttcaca gactattcac aaccaaacaa agcaactgct
     2221 gatggcgaag tagatttgaa cgctttccaa cactataact tcttgaataa ctggaacaaa
     2281 gaaaacggaa aagaccttgt agcgattgga gatacttaca tctctccaat ccgcctttac
     2341 tcaggtttga atggaagtgc caacaagtac actaaagtag aagacatccc agcaaacgga
     2401 gaaatcgctg taccgaatga cgctacaaac gaaagccgtg cgctttactt gcttcaatca
     2461 gctggcttga ttaaattgga tgtttctgga actgctcttg caacagttgc caacatcaaa
     2521 gaaaatccaa agaacttgaa aatcactgaa ttggacgcta gccaaacagc tcgttcattg
     2581 tcatcagttg acgctgccgt tgtaaacaat accttcgtta cagaagcaaa attggactac
     2641 aagaaagcac ttttcaaaga acaagctgat gaaaactcaa aacaatggta caacatcatt
     2701 gttgcgaaaa aagattggga aacatcacct aaggctgatg ctatcaagaa agtaatcgca
     2761 gcttaccaca cagatgacgt gaaaaaagtt atcgaagaat catcagatgg tttggatcaa
     2821 ccagtttggt aataagaaac agggaggtgg gagagaaaat tccacctctt gcttttgtat
     2881 agagtataga ttgtaaagaa gactattcgt tcatagaaag gtagagagaa tatgtttttt
     2941 cctagcgaac aagaacagat tgaaaaattt gaaaaggatc atgtagccca gcattatttt
     3001 gaggttttgc gtaccttgat ttctaagaaa tcagtctttg cccagcaggt tggactcaag
     3061 gaagtcgcaa actatctggg tgagattttc aagcgtgttg gagctgaagt ggagattgat
     3121 gagagctata cagcgccctt tgtcatggca catttcaaga gttcgcgtcc agatgccaag
     3181 accttgattt tctataacca ctatgacact gtgccagcgg atggggatca ggtctggaca
     3241 gaggatcctt ttacgctttc ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac
     3301 gacaagggtc atatcacagc tcgcttgagt gctttgagaa aatatatgca gcaccatgat
     3361 gatttacctg tcaatatcag ctttatcatg gagggagcgg aggaatcggc ttcaacagac
     3421 ctagataagt atttggaaaa gcatgcagac aaactctgtg gggcggattt gttggtctgg
     3481 gaacaaggga ccaaaaatgc cttggaacag ctggaaattt ctggtggcaa taagggaatt
     3541 gtgacctttg atgccaaggt aaaaagcgct gatgtggata tccactcgag ttatggtggt
     3601 gttgtggaat cagctccttg gtatctcctc caagccttac agtctcttcg tgctgcggat
     3661 ggccgtatct tggttgaagg cttgtacgaa gaagtacaag agcccaatga acgagaaatg
     3721 gccttgctag aaacttatgg tcaacgaaac ccagaggaag ttagtcggat ttatggattg
     3781 gagttgcctc tcttacagga ggagcggatg gcctttctaa aacgtttctt tttcgagcca
     3841 gcgcttaata tcgaaggaat ccagtctggt tatcaaggtc agggtgttaa gactatttta
     3901 cctgcagaag ccagtgcaaa gctagaggtt cgtctggttc cgggcctaga accgcatgat
     3961 gttctggaaa aaattcggaa acaactagac aaaaatggct ttgataaggt agaattatac
     4021 tataccttgg gagagatgag ctatcgaagc gatatgagcg caccagccat tctcaatgtg
     4081 atcgagttgg ccaagaaatt ctatccacag ggtgtttcag tcttgccgac gacagcgggg
     4141 acaggaccta tgcatacggt ctttgatgcc ctagaggtac caatggttgc attcggtcta
     4201 ggaaatgcca atagccgaga ccacggtgga gatgaaaatg tgcgaatcgc tgattattac
     4261 acccatatcg aattagtaga ggagctgatt agaagctatg agtagagata ttatcaagtt
     4321 agatcagatc gatgtgactt ttcaccaaaa gaagagaacc attacagcgg ttaaggatgt
     4381 gaccattcac atccaagaag gggatatcta cggaatcgtt ggatattctg gagcaggaaa
     4441 atcaaccctt gtacgggtga ttaacctctt gcaaaaacca tctgcaggga aaattaccat
     4501 tgacgacgat gtgatttttg atggtaaggt caccttgacg gcagagcagt tgcgtcgtaa
     4561 acgtcaagat atcgggatga ttttccagca ttttaacctg atgagccaaa agacagcaga
     4621 ggagaatgta gcctttgccc ttaaacactc tggactcagc aaggaagaaa agaaggctaa
     4681 agtagctaag ttgttggact tggttggttt ggcagatcgt gctgaaaact acccttcaca
     4741 attatctgga gggcaaaaac agcgtgtggc aattgcgcgt gccttggcca atgatccaaa
     4801 aatcttgatt tcagacgagt caacttctgc ccttgaccct aagacaacca agcagatttt
     4861 ggccttgttg caagatttga accaaaaatt aggcttgact gttgtcttga ttacgcatga
     4921 aatgcagatt gtcaaagaca ttgccaaccg tgttgcagtt atgcaggatg ggcatttgat
     4981 tgaagagggt agtgtgcttg aaatcttctc aaaccctaaa caacctttga ctcaagactt
     5041 tatctcaaca gctacaggta ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt
     5101 ggaacacttg tctgaaaaca gtctcttggt gcaactcaag tacgctggag cttcaacaga
     5161 cgagccactt ttgaatgaat tgtacaagca ttaccaagta atggctaata ttctctatgg
     5221 gaatatcgaa attctcgatg gtactcctgt tggagaattg gtggtggttt tgtcaggtga
     5281 aaaagcagcg ttggcaggtg cccaagaagc cattcgtcaa gcaggtgtac aactaaaagt
     5341 attgaaggga gtacagtaag atggaatcat tgattcaaac ctatttacca aatgtctata
     5401 agatgggttg ggctggtcag gcaggctggg gaacggctat ctacttaact ctttatatga
     5461 cagttctttc cttcattatc ggaggcttct tggggctagt ggcaggtctc tttctcgtct
     5521 tgacagcgcc aggtggtgtc ttggagaata aagtcgtatt ctggatttta gacaaaatta
     5581 cctcaatttt tcgtgcggtt ccctttatca tcctcttggc aatcttgtca ccactttctc
     5641 acttgattgt taaaacaagt atcgggccaa atgcagccct tgtcccactt tcttttgcag
     5701 tctttgcctt ctttgcccgt caggtgcagg ttgtcttggc tgaattggat ggcggtgtca
     5761 ttgaggcggc tcaagcgagc ggagcgactt tctgggacat cgtgggtgtt tacctatcag
     5821 aaggtcttcc agatttgatc cgtgtgacga ctgtgacctt gatttccctt gttggggaaa
     5881 cagctatggc cggtgcggtt ggagctggtg gtatcggtaa cgtagccatc gcttatggat
     5941 ttaaccgcta caatcacgat gtgaccatct tggcaaccat tattatcatt ttgattatct
     6001 ttgcaatcca attcttggga gatttcttga ctaagaaatt gagccataaa taaaaaagag
     6061 ccgcgtggct ctttttaact gatcagattt tctgtgcaaa ttttttactc aaggcttgtc
     6121 caatcaaagc acccactagg gctccgatga caatacttgc gataaataga aggacagttc
     6181 cagggtttgg agcgaccatg atacggtcga tatattcttg ggattttcct cttgccagaa
     6241 gagtagccat ataggctttg ggcgcaatcc acataagcaa gattggtcct gttgtactaa
     6301 aggcgaaaat aatgaaagaa aggaagttct ttgttttgtc cttgtatttt cctaaatgag
     6361 ctacttcatc tgctaggagg ccacagataa ttccaggaag gaaggaacca gcaccgtgtt
     6421 tagttcccaa gaaaaagaag gcaatgacaa ggccgatagt ggtaatggct ccaaagcgcg
     6481 gaacttttgc gactaggatc atatagacgc taccgccgac aagggcagta aaggcaggcg
     6541 cataaaacat gtttccagtt tggtcaaaga gattgcccaa aaggacacca atccccatgc
     6601 agaggaagta aagaactgca aaaagcagtg tagttaagat agatttcttc atgaattgtc
     6661 tcctgataat tttttcacaa ttctcatttt accatggttt ggtgggattg taaatggata
     6721 ctagaagttt ttgaaaacgc ttgaaatatg atataatggt ttcatagtta tttttagggg
     6781 aatatcatgg gtagattttt agactttgtc tttaatcgtt tctttttagg gatgattgcg
     6841 acagccttct tttggctatt aactttagca ggagggatta tccttggtct agcgccggct
     6901 agtgccacct tgatgagctt atatgcagaa catggttata gctttcggga atacagtttg
     6961 aaggaggctt ggtctcttta caagcaaaat tttgtctcaa gcaacctgat tttctatagc
     7021 tttttaggtg tgggtctagt tttgacctat ggtttgtatc tcttggtgca attgcctcat
     7081 cagaccattg ttcatttgat tgcgaccctt ttgaatgtct tagtagttgc cctgatcttt
     7141 ttggcttata cagtatcttt aaaattacaa gtttattttg ccttgtccta tcgaaatagt
     7201 ctcaaattat ccttgattgg catctttatg agtctagcag ctgtggccaa ggttctcctt
     7261 gggactgtgc tacttgtagc aattggttac tatatgcctg ccctgctatt ttttgtagga
     7321 attgggatgt ggcatttctt tatcagtgat atgttggaac ctgtctatga aatcatccat
     7381 gaaaaattgg cgacaaaata gaatgaagca gttttggcta catacgcttc taagaaccta
     7441 tagttcagtg atgatcatta tcattgcgag ttttgcaatc ttactctctt acgctgactg
     7501 ggattcacgt gaaaaggaag cccagagagt agcccagcgt gtaactgcta gaacagtgag
     7561 tgaaattgaa tattaccata gagagtcaac ccagatagct caggctttag ttgaaaatca
     7621 agctcgtatt gagggaatct ataaatactt tagccttagc atgccagact atttttactg
     7681 gcaattagag cggaaagctt cgccttatat atcagtctct ctgtatgaaa atgttgatga
     7741 cctctatgtt cgaaatgatt ttgtaactgg agtggccatt gcttttcaag attacaagga
     7801 agtctatgtt tctactaaag acaaacgtag tggagaaaaa atcagggctg aggatttcaa
     7861 accagcagga aatagttttg ccattccggt gtcagatcca gtgtcagatc aagatttagg
     7921 agtgatttac atctccttgg atcctgctgt tttataccat gccattgata atactagagg
     7981 taatactccg atggcagtaa cagtgacctc accttttgat acggagattt ttcatattgg
     8041 tgagacagtt gataaggaga gtgaaaattg gctagttggc ttaacttctc atggatatca
     8101 ggttcaggtg gcagttccta aaaactttgt tttacaagga acagtgacta gctctgcttt
     8161 gattgtgggt ttgagccttc tctttattgt cattctttat ctgactttga ggcagacttt
     8221 tgctaattac caaaagcagg tagtggattt agtagaatcc attcaagtca ttgctcaagg
     8281 cgaagagggt cgtcggattg acatttccga gaaagatcag gaattactcc taatcgcgga
     8341 gacgaccaat gatatgttgg atcgattgga aaagaatatc catgatattt accagttaga
     8401 gcttagtcaa aaagatgcta atatgcgagc cttgcaggcg caaatcaatc ctcattttat
     8461 gtataatacg ctggagttct tgcgcatgta tgcagttatg cagagtcaag atgagttggc
     8521 agatatcatt tatgaattca gtagtctctt gcgtaacaat atttccgacg aaagagagac
     8581 cctcctcaaa caggaattag aattttgccg taaatacagc tatctctgca tggttcgcta
     8641 tcccaagtcc attgcctatg gtttcaagat agatccagag ttagagaata tgaagattcc
     8701 taagttcacc ttgcaaccgc tggtagaaaa ttatttcgcg catggtgttg accacaggcg
     8761 gacagataat gtgattagca tcaaggctct taaacaggat ggttttgtgg aaattttggt
     8821 ggtcgataat ggtagaggaa tgtcggctga aaagttggca aatatccgag aaaaattaag
     8881 tcagagaaat tttgaacacc aagccagcta cagtgatcaa aggcagtcta tcgggattgt
     8941 caatgtacac gagcgttttg tgctctattt tggagaccgc tatgccatta ctatagagtc
     9001 tgcagagcaa gccggtgttc agtatcgtat tacaattcaa gatgagtaga aagggagaaa
     9061 atgtataaag tattattagt agatgatgag tacatggtga cagaaggtct gaagcgtttg
     9121 attccctttg ataagtggga tatggaggtc gtcgcaacag ccagtcatgc cgatgaagct
     9181 ctagaatatg ttcaggaaaa tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac
     9241 aaaacagggc ttgatatgat tcgggagatg aaagagatct taccagatgc tgcctatatc
     9301 ctgctctcag gttatcagga gtttgattat gtaaaaagag caatgaacct tagtgtggtg
     9361 gactatttgg tcaaacctgt tgataaggta gagctgggaa atctgctgga gaagattgca
     9421 ggtcagctcg gcgagagagg gaagaaaagt cagactctta gtcaagaatt agacgaggct
     9481 ggatttgtta gttatttagg ggataaggag aattggtgga taggtctatc caaggaaaaa
     9541 caaggttcct tcaccattcc ctactatgtc ttgggtcaag cctggcagat tttcatttct
     9601 gaccaacccc tagatggttt agtcgttaca ccttttgaag ctccttatca agaacatttt
     9661 gaacgctgga agctgaatgc tgagaaaacc ctcttttacg gttctgtaaa tctgcagcag
     9721 tctgagagtc tctttgccta ttacgaaccg atttataggg ttatcattca gggaaatctc
     9781 aatcaaatcg tagaagagtt aaatctcttg gagaaggtag ttcttgaaaa tacgccgcga
     9841 attccgatta ctaaacagct ttttatccag tttgtcatgg atgtcttcca tttatttgaa
     9901 catctcaaag ctgatgatat gacggacatt gtcaaaacca ttcatgctat tcaatccttc
     9961 gatgaattgg tttcttatat caaggaaact ctgatcagct ttttcggtca ataccgtatg
    10021 aatgaaaatg tggtcagtgt gctggaagtc attggtcgtg attaccaaaa agagctttcc
    10081 ctcaaggata tcagtaaggc cctctttatc aatcctgtct atctagggca gttgattaag
    10141 cgtgaaaccg attcgacctt tgcagagtta ctaaacaaac aacgtattaa ggctgcccag
    10201 cagctcttgc tttcaaccag tgacagtatc gaagatattt gttatgctgt tggttacagt
    10261 aaccttggat atttctataa agttttccga aaattgtgcg gaaaatcgcc aaaagcctac
    10321 cgaaaacagg tagaaactat actataagat ttgtattcct ttacaaaatg tgctataata
    10381 ttatcaggag gttctatcat gaaaaagaaa ccaatttatc tatgggtctt gctaatcttg
    10441 tctgccctta tttcagttcc gtctctgttt ggaattgtga gtcccttgcc tagtaaagaa
    10501 gcccttcgtg ttgctcagaa acaagttgca ggggtcaatg ctcagcaatt agaagaccag
    10561 cttaattata cctatagagt agcagaagca tctcattcta tttttaatgt tgctttgatt
    10621 gtgctatcta ctattttagt ggtcgtagcg attgtcttcc ttgttcgtaa aaatttgcaa
    10681 tatgcaaact atacttacgt tggctatgtt ttgttagcta ttattggttc gatttatggc
    10741 tatgttggtt tacaagacgc tgtgcagttg gttcaagatg agagcatgcg tttgacagtg
    10801 agtattggtt caaaagctgt tagcattttc tatatcgtca tcaatgttct cttcctagcc
    10861 cttgtcttct ataagatgtg gcgacaacag aaagccttgg cagaagaaga ggaaacagaa
    10921 gagcttgcct aagtattgac aaaaaagaac tatcaagata caatcttggt agttattttt
    10981 tgattataga taaaatcatg gaggtacata tgaagacaat ttctttagtt tatattagtt
    11041 tgagtggcaa cactgaaagt tttgtgacgc gcttgaaaga ctatctcttg tcccagtaca
    11101 aagggattga ggttcaaaag attcatatca aggatttggt caaggaaggc aaaaatttct
    11161 atgaaatgga ccatctctat gtcgcttttt tgccgaccta tctcgaaggt gggaatggcg
    11221 tggataacgg agatgttgag attttgacaa caccggtggg agattttatt gcctatggta
    11281 acaatgctag taagtgtttt ggtgtggttg ggtcaggaaa tcgtaacttt aataaccaat
    11341 actgcctaac agccaagcaa tacagtcaac gctttggctt ccctgtattg gctgactttg
    11401 aaatgcgagg catgctggaa gatatcaaac atgtcgcagc tattatcgca gatttgtatg
    11461 agttggaaaa ggagaattaa tactcaatga aaatcaaaga gcaaactagg aagctagtcg
    11521 caggttgctc aaagcacagc tttgaggttg cagatagagc tgacgtggtt tgaagagatt
    11581 ctcgaatagt ataaagttct tataagaggt ggttgaagtt gttcaactgt tttttgagta
    11641 taaacagtct ttaagaacgt aaaaaagcat aagttcaggt cttcaaaacc ttgttcttat
    11701 gctttttatc atagaaatat ttgctgaatt ttctcttgaa atgaaacctt atcttcatct
    11761 cgcgcttgtc ccttaccctg cttttccgat tgcgagtgcg tagataaaga agatggcgaa
    11821 gccaaagagg aaaatcaatc ccgcaatggc aaggtgtttg agccaagaag gaagattttt
    11881 gttttcacgc gttaccaagg cgtaattcaa aagagcaaag aaaggtgttg tcaggaaaga
    11941 tccaatcatg gcaaagcgga gcatggttga aacctgacca gcgaagaact tgataatgac
    12001 gataccgatg atagcagtga tggtcatcca gatgttcaaa gatttacgat tgtcctcttt
    12061 ttgactgatt agcagtcgga gagattcctg attaacgcga gaatagccat cgataacagt
    12121 tataactgtt ccaaagatac agaggaaggc aataaaggta atcaagtaac gggaccattc
    12181 gccaagaaca gaggcataca tgcccacgaa ttgagagatg tatttggctg aagcagcttc
    12241 aaccgcctgc cctgtaggat actgaatcag tgctcccagt gccacaaaga agacggctag
    12301 gatagctgtt ccaatataac cagtgttaaa gtcaaacaga gcgtcttctg tgttaaagtt
    12361 gacggtcttt ctcttttcag ctgaccaaag tgaattgata gctgaaattt caataggagc
    12421 cggcatccat cctaggaggg agacgatgaa gggcagagct gccatttgcc aaggtgtctt
    12481 ctcgacaaaa tcagaactgt attctggatg cttgaccgct gctatgataa ctgccagaac
    12541 agtcgcaatg gttaaggcag acataatcca tttgaccatg ccgtctaaaa gtttgtagcc
    12601 tccaaagagt agcatagccc aaatgattgc aacgagaatg agggaccact gagtaatgct
    12661 aagtccaatc attgggaagg cactggcgat gatagctgag cacagaatgg caacaccagc
    12721 cgtgttgacc atagccgaaa agacattgag gataaagaaa atccagagat agagttttcc
    12781 tttttcggca taaccttcaa ccaaagtctt tccagtatca gctgtgtatt cagcaccaaa
    12841 acggaaaaat ggatatttaa agacattggc taagatgact aagagaagta gagaccaacc
    12901 gtaagaaccg ccagcttgag ttgaggatac aatgtgggaa cctccaacag cggcagttgc
    12961 cattaggatt ccaggtccca ttgcttttag cttgcttgcc caggttgatt gatttaagga
    13021 aatagcttgc gacatgataa atactccttt ttgaattttc agaataatct gtatatgtaa
    13081 tctatattct acaaaaaatt ttggaaaaat gcaagaatat tttgaaaaaa gatagaaaat
    13141 ttacaaagaa aatctgaaat aactgttatg atatag
//
LOCUS       DAVBOM010000055        13159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBOM010000055 DAVBOM010000000
VERSION     DAVBOM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.055"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..367
                     /locus_tag="VQ878_001761"
     CDS             <1..367
                     /locus_tag="VQ878_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3096066.1"
                     /translation="PNLEQVQTMLEQTFTEKHYENTILHSDQGWQYQHDSYHQFLESK
                     GIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSRKQLEQAIVDYIDYYNNKR
                     IKVKLKGLSLVQYRTKSFG"
     gene            complement(442..972)
                     /locus_tag="VQ878_001762"
     CDS             complement(442..972)
                     /locus_tag="VQ878_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET3096067.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(966..1434)
                     /locus_tag="VQ878_001763"
                     /pseudo
     CDS             complement(966..1434)
                     /locus_tag="VQ878_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1984..2661
                     /locus_tag="VQ878_001764"
     CDS             1984..2661
                     /locus_tag="VQ878_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET3096068.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2648..3445
                     /locus_tag="VQ878_001765"
     CDS             2648..3445
                     /locus_tag="VQ878_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET3096069.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3462..4565
                     /locus_tag="VQ878_001766"
     CDS             3462..4565
                     /locus_tag="VQ878_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET3096070.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4866..5885
                     /gene="galE"
                     /locus_tag="VQ878_001767"
     CDS             4866..5885
                     /gene="galE"
                     /locus_tag="VQ878_001767"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3096071.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5887..6840
                     /locus_tag="VQ878_001768"
     CDS             5887..6840
                     /locus_tag="VQ878_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3096072.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6902..7108)
                     /locus_tag="VQ878_001769"
     CDS             complement(6902..7108)
                     /locus_tag="VQ878_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET3096073.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7160..7636
                     /locus_tag="VQ878_001770"
     CDS             7160..7636
                     /locus_tag="VQ878_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET3096074.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7645..8316
                     /locus_tag="VQ878_001771"
     CDS             7645..8316
                     /locus_tag="VQ878_001771"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET3096075.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8447..8785
                     /locus_tag="VQ878_001772"
     CDS             8447..8785
                     /locus_tag="VQ878_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET3096076.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8788..9417
                     /locus_tag="VQ878_001773"
     CDS             8788..9417
                     /locus_tag="VQ878_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET3096077.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9657..10808
                     /locus_tag="VQ878_001774"
     CDS             9657..10808
                     /locus_tag="VQ878_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3096078.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11126..11875
                     /gene="truA"
                     /locus_tag="VQ878_001775"
     CDS             11126..11875
                     /gene="truA"
                     /locus_tag="VQ878_001775"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET3096079.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11865..12638
                     /locus_tag="VQ878_001776"
     CDS             11865..12638
                     /locus_tag="VQ878_001776"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3096080.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKVFVYRAIAQADQYGVRQYEANKNN"
     gene            12616..13077
                     /locus_tag="VQ878_001777"
     CDS             12616..13077
                     /locus_tag="VQ878_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3096081.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3762 a         2466 c         2904 g         4027 t
ORIGIN      
        1 acccaactta gaacaagtac aaacaatgtt ggaacagaca ttcacagaga agcactacga
       61 gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt
      121 cctagagagt aagggaattc aagcatccat gtcacgtaag ggcaacagcc cagacaacgg
      181 tatgatggag tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc
      241 gtttcagtcg cgtaagcaat tggaacaagc tattgtagac tatattgatt actacaacaa
      301 taaacgaatt aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt
      361 cggataaatt aattgtctaa ctttttgggg ggcagtacat ttttggtata tataaaattt
      421 gtaggagcta tatctacaat tttatattcc cagtttatgg atgtcgctta ctatgttcac
      481 aatgttatcc agtgtttttt ctctaatatt taaggagtgt tctgtttctc gaataaattc
      541 ttcaaagttt aacccgtcaa cttgttcctg aacaagaaaa taatcatcca cgatataaaa
      601 ttcatcagtt aaattagtag tataactttt atcggctaat ttttttagca tgtaagcctc
      661 attttttata tcatcaagtg ctgtccattc tccttcggca tcataattca caaaaggtct
      721 tgactgcttg atgattactt tttgcccgtc cgattttcta attgcccgat aaacattccc
      781 tttatttgat ctcttaataa ttttttctat tttgtattta tttattgcag agtccttact
      841 tgaaacttca catgtggttt gaaaataaat ccttttttct tcttctgaaa ataaatccat
      901 tttccagcta ggaagactag ggaaattttg tctcttatct tctacatagt tcttcctttt
      961 ttcatctagc aataaataga tgactttttt atttttttca tcataagctt gtttttttaa
     1021 aaaagcccca tatctataat gaactggaga atgcattcca cattgatagt cagatagtat
     1081 ttttggagcc ttaaattctg acagtctatt cgtaagatta caaatcatac tcttagcttc
     1141 agattctgac ttaggatata gagttataaa tttgttagca gtagggctca tttccctagg
     1201 ggaattaatt ctttttaatt cctctaaatt tttaacaact ttaaagctac aattatttag
     1261 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1321 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1381 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1441 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1501 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1561 gggagacctg tgacaatgat atcttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1621 tccatgactg tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1681 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1741 attttttcta actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg
     1801 aataaactgt ttatttttta tttttttgac atttttgcaa attgtttaaa atctttcaat
     1861 tggattcact tattacttta ggacattgaa gcttctttcg ccagaggtgc ttatattact
     1921 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagagagag
     1981 aagatgattt caaagagatt agagttggta gcttcctttg tgccgcaggg agccatttta
     2041 ctagatgtgg ggagtgacca tgcttatttg cctatagagt tagtcgaaag aggaaaaatc
     2101 gaaagtgcca ttgcaggtga agttgtggag ggaccttatc agtctgctgt caaaaatgtt
     2161 gaggcccacg gcttggaaga aaaaatccaa gtccgtttag ccaatggttt ggcagctttt
     2221 gaagaggaag accgagtgtc tgtcattacc atcgcaggga tgggcggccg tttgattgct
     2281 aggattttag aagaaggctt ggacaagtta gctaacgtag agcgtttgat tctccagccc
     2341 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2401 gaaagcatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
     2461 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
     2521 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
     2581 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2641 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2701 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2761 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2821 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2881 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2941 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     3001 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3061 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3121 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3181 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3241 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3301 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3361 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3421 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3481 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
     3541 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
     3601 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3661 acttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3721 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
     3781 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3841 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3901 gtggagcgag agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca
     3961 agctggtcaa agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag
     4021 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
     4081 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
     4141 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
     4201 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
     4261 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
     4321 ctagagcgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
     4381 ccttctttgg gcaggtgcca gaattggcag gtgtctatgt agccagtgga ctaggttcat
     4441 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
     4501 agttgacctt ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4561 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4621 actgctttga ggttgtgtat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     4681 tgtatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
     4741 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
     4801 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
     4861 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
     4921 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
     4981 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
     5041 cagatattcg tgacacagtt accctcagag atattttcaa gcaggaagaa ccgactggtg
     5101 tcattcactt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
     5161 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
     5221 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
     5281 tggaagattt cccactttca gtgaccaacc catacggtcg taccaagctc atgctagagg
     5341 aaattttgac cgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
     5401 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
     5461 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
     5521 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
     5581 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
     5641 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
     5701 aagcggtggg acgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
     5761 cctgctactc agacccagca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
     5821 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
     5881 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
     5941 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
     6001 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
     6061 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
     6121 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
     6181 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
     6241 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
     6301 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
     6361 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
     6421 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
     6481 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
     6541 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
     6601 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
     6661 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc
     6721 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
     6781 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga
     6841 aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga
     6901 tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga
     6961 catcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga
     7021 ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac
     7081 atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa
     7141 aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga
     7201 agaatcaaga gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg
     7261 tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct
     7321 catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc
     7381 tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga
     7441 gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt
     7501 tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt
     7561 agaggccttg aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt
     7621 tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct
     7681 tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt
     7741 gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt
     7801 gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca
     7861 gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa
     7921 aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg
     7981 gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt
     8041 ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag
     8101 agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc
     8161 ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc
     8221 aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt
     8281 gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat
     8341 atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga
     8401 gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc
     8461 aaattgtccc aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc
     8521 agagtgtgct catgagtgga atcctgctga agttgcagaa gtagaagaag gtcttgtcgc
     8581 tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt
     8641 gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat
     8701 cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa
     8761 atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc
     8821 cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt
     8881 ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc
     8941 ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg
     9001 cgcttaaaag gtggggtcac catgagcatc atgattacct gtgtgattta ccatttcctc
     9061 ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt
     9121 cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg
     9181 gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc
     9241 ttggttctaa aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg
     9301 aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat
     9361 atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac
     9421 tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa cactgttttg
     9481 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaag
     9541 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
     9601 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
     9661 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
     9721 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
     9781 ttgagctctt ggtgagcttg ccttcctttg gaattatgat gatgttactg ctaaatggtt
     9841 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
     9901 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
     9961 tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct
    10021 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag
    10081 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
    10141 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
    10201 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
    10261 aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta
    10321 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
    10381 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
    10441 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
    10501 aaattgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg
    10561 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
    10621 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
    10681 cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
    10741 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
    10801 gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca aagagcaaac
    10861 tatagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    10921 ttgactttcc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    10981 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    11041 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    11101 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    11161 ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg aagaaattga
    11221 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    11281 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagattga
    11341 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    11401 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    11461 gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    11521 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    11581 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    11641 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttccggaaa
    11701 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    11761 ccgcatgcca gtagagcaga ttgctctcat cttggagaag aaggacaggc aacttgcagg
    11821 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    11881 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    11941 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    12001 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    12061 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    12121 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    12181 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    12241 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    12301 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    12361 ctccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    12421 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    12481 gtgcaggttg tacctttgcc tctagcattg ccagtcactt ggttaaaggt gataaacttt
    12541 tgccagcagt agaaagttct aaggttttcg tttatcgtgc tattgcacaa gcagatcagt
    12601 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    12661 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    12721 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    12781 gtagtcggag gactagcaag tttcttgctt gacctcttat caggctaccc tcagtggatg
    12841 ttttttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    12901 cagtggttag gccttatttt agcaactatt gccatggtag ggggctacgc cttgggttct
    12961 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt tatgcaaaat
    13021 atggcaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    13081 tcttcgaaaa tctcttcaaa ccacgtcggc ttccatctgc aacctcaaaa cactgttttg
    13141 agcagcctgc ggctagctt
//
LOCUS       DAVBOM010000056        12973 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBOM010000056 DAVBOM010000000
VERSION     DAVBOM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.056"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VQ878_001778"
     CDS             87..3437
                     /locus_tag="VQ878_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3096082.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3681..3782
                     /locus_tag="VQ878_001779"
                     /pseudo
     CDS             3681..3782
                     /locus_tag="VQ878_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4023..4493)
                     /locus_tag="VQ878_001780"
     CDS             complement(4023..4493)
                     /locus_tag="VQ878_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3096083.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4510..6783)
                     /locus_tag="VQ878_001781"
     CDS             complement(4510..6783)
                     /locus_tag="VQ878_001781"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET3096084.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7129..10230
                     /locus_tag="VQ878_001782"
     CDS             7129..10230
                     /locus_tag="VQ878_001782"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET3096085.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDEQEVNLRFLSLSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YKLSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIQVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ878_001783"
     CDS             10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ878_001783"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET3096086.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11379..12884
                     /gene="pyk"
                     /locus_tag="VQ878_001784"
     CDS             11379..12884
                     /gene="pyk"
                     /locus_tag="VQ878_001784"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET3096087.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4023 a         2203 c         2850 g         3897 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggctga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga
     3781 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     3841 accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat
     3901 cttcctagga taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt
     3961 tttctgatgt taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt
     4021 tattattctt caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga
     4081 gcagtatctg catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata
     4141 gcgtcaggga agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg
     4201 gtttttagta ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag
     4261 agttcgagac gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta
     4321 tcttcttcgc ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg
     4381 gttacttgaa tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg
     4441 ttttttgtga taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg
     4501 taactccttt tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta
     4561 gtctgtattg tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt
     4621 gtctccttct tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc
     4681 atctgcagta atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc
     4741 ttttgtcacg actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat
     4801 gtgatagcga ccgttatcaa tggttctagc acttaaaata gctggataag gttgtaggta
     4861 tttcttttgc ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt
     4921 gatacgaaga ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt
     4981 aatagtaatc tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt
     5041 actatagcgc tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc
     5101 aagtgagaag gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg
     5161 tggagctgta ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag
     5221 taatttcttg gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt
     5281 catgtaaaca tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc
     5341 atggaacatc tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa
     5401 gacaacctct gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg
     5461 attgtagtcc ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg
     5521 agcttcattg ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc
     5581 aagggagtca aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg
     5641 gtagtagttg taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac
     5701 tcctgtagtc gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac
     5761 ttttccgttt gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcacg
     5821 gcaacggccg ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc
     5881 attagtcatg aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa
     5941 gcctctcgga aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc
     6001 ctcagcctct gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt
     6061 ctctagctca atcttgtgag gaagcttaac ctcaagctcg ccctccatct tgtagagagc
     6121 cttgtcacta gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg
     6181 gatttttcca tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt
     6241 ttggtcagta tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga
     6301 aaaagtagcc aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc
     6361 atcactaaca agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg
     6421 atagagattt tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac
     6481 gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata
     6541 aaaaatatct gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt
     6601 atcagctgct aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg
     6661 taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt
     6721 ttttagctca gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg
     6781 catagaacct ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg
     6841 gaattgttaa cttcaaaagg aaataatcca ataaaaatga ataaagtact aaattcaata
     6901 tagagaacag agtaacaata agaataatag atagggtata aaagttctag gagatttata
     6961 ttatatgctt tctattttta tatacaatat agtataaata taaaaatgat gacaaaaata
     7021 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     7081 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     7141 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     7201 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     7261 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     7321 gaaatgacag tgtttgtaga tgaacaggaa gtgaatttgc gctttttatc tctatctagt
     7381 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     7441 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     7501 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     7561 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     7621 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     7681 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagtgt
     7741 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     7801 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     7861 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     7921 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     7981 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     8041 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     8101 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     8161 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     8221 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     8281 ttgaaacgct ttggtgtgcc agagtataaa ttatctgcaa ttactaagaa aatcagtttt
     8341 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     8401 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     8461 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     8521 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     8581 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     8641 gagttgcttg ctgaaacaga aggtattcac cttaaaattg aagaaataga tttggaagac
     8701 aaagaaacgt tagatttatt tgcctctgga aatacaaaag gtatctttca atttgagcaa
     8761 cctggtgcca ttcgcttgct caaacgtgtt caaccagtct gttttgaaga tgtcgtagca
     8821 actacttctc taaatcgacc aggtgcaagt gactacatca ataattttgt ggcaaggaag
     8881 catgggcagg aagaagtgac tgttctagat tcagctctgg aggatatttt ggctccaact
     8941 tatggcatta tgctctatca ggagcaggtt atgcaggttg ctcagcgatt tgctggattt
     9001 agtcttggga aggccgatat tttgcgtcga gctatgggta aaaaggatgc ctctgctatg
     9061 catgagatga gggcttcctt tattcaaggc tccatagaag caggccatac tgcggaaaaa
     9121 gcagagcagg tttttgatgt tatggagaag tttgcaggtt atggatttaa tagatctcat
     9181 gcctacgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     9241 attttttatc aggtcatgtt aaattattcc aacagtgatt acttaataga tgcacttgaa
     9301 gcaggttttg aagtagcctc tctatccatc aatactattc cctatcacga taaaattgcc
     9361 aacaagtcta tctatatagg tttgaaatcg attaaggggc tcagcaagga cttggcgctt
     9421 tggattattg aacatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     9481 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     9541 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     9601 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     9661 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     9721 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     9781 agctatgcta ttattttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     9841 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt cactctcttt
     9901 tcagacttat atcgtcaggt tggacaggaa ataaaagagg gagccttcta ctatgtaaaa
     9961 ggaaaaatac aatcacgtga tggccgtttg caaatgattg cacaagaaat aagagaagca
    10021 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
    10081 attttagaac aatttaaagg cccaatccaa gtcatcatcc ggtatgaaga ggaacagaaa
    10141 accatcgttt ctccccatca ttttgtagct aaatccaatg aattagagga gaaattgaat
    10201 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
    10261 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaacca atatgaaacg
    10321 tattgctgtt ttgactagtg gcggagacgc acctggtatg aacgctgcta tccgtgcagt
    10381 tgttcgtcaa gcaatttcag aaggaatgga agtgtttggt atctatgacg gatatgctgg
    10441 tatggttgcc ggtgaaattc atcccctaga tgcagcttca gtaggagaca tcatttctcg
    10501 tggtggtact tttcttcact cagctcgtta cccagagttc gctcaacttg aagggcaact
    10561 taaagggatt gagcaattga aaaaacacgg aattgaaggt gtagttgtta tcggtggtga
    10621 cggatcttac cacggcgcta tgcgtttgac tgaacatggc ttcccagcta ttggtcttcc
    10681 aggtacaatc gataacgata tcgttggtac tgactttaca atcggttttg acacagcggt
    10741 tactactgcc atggacgcta tcgataagat tcgtgataca tcatcaagtc accgtcgtac
    10801 ttttgtaatc gaagttatgg gacgtaacgc tggtgatatc gctctttggg ctggtattgc
    10861 aactggtgct gatgaaatca tcatccctga agcaggcttc aagatggaag atatcgtagc
    10921 aagcatcaaa gctggttatg aatgtggtaa aaaacacaat atcatcgtct tagctgaagg
    10981 tgtgatgtca gcggctgaat ttggtcaaaa acttaaagaa gctggagata caagcgacct
    11041 tcgtgtaaca gaacttggac atattcaacg tggtggttct ccaactgcgc gtgaccgtgt
    11101 tttagcgtca cgtatgggtg cacatgctgt taaacttctt aaagaaggta tcggtggtgt
    11161 tgcggttggt attcgtaacg aaaaaatggt tgaaaatcca attcttggta ctgcagaaga
    11221 aggggcattg tttagcctta ctgcagaagg taagattgtg gttaacaacc cgcacaaagc
    11281 cgatattgag ctatctagct tgaataagag cttgtcataa tttacaattt agttaataag
    11341 accaaaaagg tcatatatat aaaggagtca caaaaatcat gaacaaacgt gtaaaaatcg
    11401 ttgcaacttt gggtcctgcg gtagaaatcc gtggtggtaa aaaattcggt gaggacggat
    11461 actggggtga aaaacttgat gttgaagctt cagctaaaaa cattgctaaa ttgattgaag
    11521 ctggtgctaa cacattccga ttcaacttct cacacggcga ccaccaagaa caaggtgagc
    11581 gtatggcaac tgttaaactt gcggaaaaaa ttgcaggtaa aaaagttggt ttccttcttg
    11641 atacaaaagg acctgaaatc cgtacagaat tgttcgaagg tgaagctaaa gaatattcat
    11701 acaaaactgg tgaaaaaatt cgtgttgcaa ctaaacaagg aatcaaatca actcgtgaag
    11761 tgattgcgtt gaacgttgct ggtgctcttg atatctatga tgatgttgaa gttggtcgtc
    11821 aagttttggt tgacgatggt aaacttggtc ttcgtgtggt tgctaaagat gatgcaactc
    11881 gtgaatttga agttgaagtt gaaaacgatg gtatcatcgc taaacaaaaa ggtgtgaaca
    11941 tccctaacac taaaattcct ttcccagctc ttgctgaacg cgataacgac gatatccgtt
    12001 tcggtcttga acaaggtatc aacttcatcg caatttcatt cgtacgtact gcaaaagatg
    12061 tgaacgaagt tcgtgcaatc tgtgaagaaa ctggaaacgg acatgttcaa ttgttcgcta
    12121 aaatcgaaaa ccaacaaggt atcgataact tagacgaaat catcgaagca gctgatggta
    12181 ttatgattgc tcgtggtgat atgggtatcg aagtaccgtt cgaaatggtt ccagtttatc
    12241 aaaaaatgat tatcaagaaa gtcaatgctg caggtaaagt tgttatcact gcaacaaaca
    12301 tgcttgaaac aatgactgaa aaaccacgtg caactcgttc agaagtatca gacgtattca
    12361 acgctgttat cgacggaact gacgctacaa tgctgtcagg cgagtctgca aacggtaaat
    12421 acccactcga gtcagtaact acaatggcta caatcgacaa gaacgctcaa gctcttctta
    12481 atgaatacgg acgtcttgat tcagattcat ttgagcgtaa ctctaagaca gaagtaatgg
    12541 cttctgctgt taaagatgct actaactcaa tggatatcaa attggttgta actcttacta
    12601 agacaggtca tactgcacgt ttgatttcta aataccgtcc aaatgctgac atcttagcat
    12661 tgacatttga cgaattgaca gaacgtggct tgatgttgaa ctggggtgtt atcccaatgt
    12721 tgacagatgc tccatcttca actgacgata tgttcgaaat cgctgaacgt aaagcggtag
    12781 aagcaggtct cgttgagtca ggcgatgata tcgttatcgt tgctggtgtg ccagtaggag
    12841 aagctgttcg cacaaacaca atgcgtatcc gcacagtacg ttaagaaaaa tataaaaacc
    12901 tatcatatcc agctttctag cctgtatgat gggctctttt tttgtccagg gggcaaaact
    12961 ttcataatgg att
//
LOCUS       DAVBOM010000057        12081 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBOM010000057 DAVBOM010000000
VERSION     DAVBOM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.057"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            409..636
                     /locus_tag="VQ878_001785"
     CDS             409..636
                     /locus_tag="VQ878_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096088.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            924..4061
                     /gene="nanA"
                     /locus_tag="VQ878_001786"
     CDS             924..4061
                     /gene="nanA"
                     /locus_tag="VQ878_001786"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET3096089.1"
                     /translation="MNRSIQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKENEYFTMSVLDNTALIEGRGANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAE
                     LPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKTVWGSNLQVRNLTV
                     YDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTARFMTQYDTKTLLFTVDSEDMGQKVTGLAEG
                     AIESMHNLPVSVAGTKLSNGMNGSEAAVHEVPEYTGPLGTSGEEPAPTVEKPEYTGPL
                     GTSGEEPAPTVEKPEYTGPLGTSGEEPAPTVEKPEYTGPLGTAGEEAAPTVEKPEFTG
                     GVNGTEPAVHEIAEYKGSDSLVTLTTKKDYTYKAPLAQQALPETGNKESDLLASLGLT
                     AFFLGLFTLGKKREQ"
     gene            5076..5528
                     /locus_tag="VQ878_001787"
     CDS             5076..5528
                     /locus_tag="VQ878_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3096090.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFIYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5547..6884
                     /locus_tag="VQ878_001788"
     CDS             5547..6884
                     /locus_tag="VQ878_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3096091.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6963..7847
                     /locus_tag="VQ878_001789"
     CDS             6963..7847
                     /locus_tag="VQ878_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3096092.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7847..8680
                     /locus_tag="VQ878_001790"
     CDS             7847..8680
                     /locus_tag="VQ878_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3096093.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8698..10791
                     /gene="nanB"
                     /locus_tag="VQ878_001791"
     CDS             8698..10791
                     /gene="nanB"
                     /locus_tag="VQ878_001791"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET3096094.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKADFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10803..11906
                     /locus_tag="VQ878_001792"
     CDS             10803..11906
                     /locus_tag="VQ878_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3096095.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
BASE COUNT         4063 a         1927 c         2531 g         3560 t
ORIGIN      
        1 ctatctgcca cctcaaaacg gtgttttgag ctgactttgt cagtcttatc tacaacctca
       61 aaacagtgtt ttgagcatca tgcggctagc ttcttagttt gctctttgat tttcattgag
      121 tataaaaaca gatgagtttc tgttttcttt ttatggacta taaatgttca gctgaaacta
      181 ctttcaagga cattattata taaaagaatt ttttgaaact aaaatctact atattacact
      241 atattgaaag cgttttaaaa atgaggtata ataaatttac taacgcttat aaaaagtgat
      301 agaatctatc tttatgtata tttaaagata gattgctgta aaaatagtag tagctatgcg
      361 aaataacaga tagagagaag ggattgaagc ttagaaaagg ggaataatat gatatttaag
      421 gcattcaaga caaaaaagca gagaaaaaga caagttgaac tacttttgac agtttttttc
      481 gacagttttc tgattgattt atttcttcac ttatttggga ttgtcccctt taagctggat
      541 aagattctga ttgtgagctt gattatattt cccattattt ctacaagtat ttatgcttat
      601 gaaaagctat ttgaaaaagt gttcgataag gattgagcag gaagtatggt ataaatagca
      661 taagctgatg tccatcattt gcttataaag agatatttta gtttaattgc agcggtgccc
      721 tggtagataa actagattgg caggagtctg attggagaaa ggagagggga aaattggcac
      781 caatttgaga tagtttgttt agttcatttt tgtcatttaa atgaactgta gtaaaagaaa
      841 gttaataaaa gacaaactaa gtgcattttc tggagtaaat gtcttatttc agaaatcggg
      901 atatagatat agagaggatc agtatgaatc ggagtattca agaacgtaag tgtcgttata
      961 gcattaggaa actatcggta ggagcggttt ctatgattgt aggagcagtg gtatttggaa
     1021 cgtctcctgt tttagctcaa gaaggggcaa gtgagcaacc tctggcaaat gaaactcaac
     1081 tttcgggggg gagctcaacc ctaactgata cagaaaagag ccagccttct tcagagactg
     1141 aactttctgg caataagcaa gaacaagaaa ggaaagataa gcaagaagaa aaaattccaa
     1201 gagattacta tgcacgagat ttggaaaatg tcgaaacagt gatagaaaaa gaagatgttg
     1261 aaaccaatgc ttcaaatggt cagagagttg atttatcaag tgaactagat aaactaaaga
     1321 aacttgaaaa cgcaacagtt cacatggagt ttaagccaga tgcatcagct ccacgctttt
     1381 acaatctctt ctctgtatcc agtgacacca aggaaaatga gtactttact atgtcggtcc
     1441 ttgataatac agctcttatt gaagggcgtg gcgctaacgg agagcagttc tatgataagt
     1501 atacagatgc tcctttgaaa gttcgcccag gacaatggaa ttccgtgacc tttactgtcg
     1561 aacaaccgac agcggagtta cctcatggac gagttcgtct ctatgtgaac ggtgtcttat
     1621 ctcgaacaag tctcaaatct ggtaacttta tcaaagatat gccagatgtt aatcaagctc
     1681 aacttggagc aaccaaacgg ggcaataaga cagtttgggg aagcaatcta caagttcgaa
     1741 acctaaccgt ctatgatcgt gccttaagcc cagaagaagt tcagacgaga agccaactat
     1801 ttgaaagagg tgatttggag aagaaacttc cagaaggtgc gaaaatctca gagaaagaag
     1861 acgtctttga agggggaatg aacaacaaac caaataaaga tggaattaag agttatcgta
     1921 ttccagctct tctcaagaca gataaaggaa ctttgatcgc aggtgcagat gaacgccgtc
     1981 tccattcgag tgactggggt gatatcggta tggtcatcag acgtagtgaa gataatggta
     2041 aaacttgggg tgaccgagta accattacca acttacgtga caatccaaaa gcttctgacc
     2101 catcgatcgg ttcaccagtg aatatcgata tggtgttggt tcaagatcct gaaaccaaac
     2161 gaatcttttc tatctatgac atgttcccag aagggaaggg aatctttgga atgtcttcac
     2221 aaaaagaaga agcctacaaa aaaatcgatg gaaaaaccta tcaaatcctc taccgtgaag
     2281 gagaaaaggg agcttatacc attcgagaaa atggtactgt ctatacacca gatggtaagg
     2341 cgacagacta tcgcgttgtt gtagatcctg ttaaaccagc ctatagcgac aagggtgatc
     2401 tatacaaggg tgaccaatta ctaggaaata tctacttcac aacaaacaaa acttctccat
     2461 ttagaattgc caaggatagc tatctatgga tgtcctacag tgatgacgac gggaagacat
     2521 ggtcagctcc tcaagatatt actccgatgg tcaaagccga ttggatgaaa ttcttgggtg
     2581 taggtcctgg aacaggaatt gtacttcgga atgggcctca caagggacgg attttgatac
     2641 cggtttatac gactaataat gtatctcact tagatggctc gcaatcttct cgtgtcatct
     2701 attcagatga tcatggaaaa acttggcatg ctggagaagc ggtcaacgat aaccgtcagg
     2761 tagacggtca aaagatccac tcttctacga tgaacaatag acgtgcgcaa aatacagaat
     2821 caacggtggt acaactaaac aatggagatg ttaaactctt tatgcgtggt ttgactggag
     2881 atcttcaggt tgctacaagt aaagacggag gagtgacttg ggagaaggat atcaaacgtt
     2941 atccacaggt taaagatgtc tatgttcaaa tgtctgctat ccatacgatg cacgaaggaa
     3001 aagaatacat catcctcagt aatgcaggtg gaccgaaacg tgaaaatggg atggtccact
     3061 tggcacgtgt cgaagaaaat ggtgagttga cttggctcaa acacaatcca attcaaaaag
     3121 gagagtttgc ctataattcg ctccaagaat taggaaatgg ggagtatggc atcttgtatg
     3181 aacatactga aaaaggacaa aatgcctata ccctatcatt tagaaaattt aattgggaat
     3241 ttttgagcaa aaatctgatt tctcctaccg aagcgaaagt gaagcgaact agagagatgg
     3301 gcaaaggaga gatgggcaaa ggagttattg gcttggagtt cgactcagaa gtattggtca
     3361 acaaggctcc aacccttcaa ttggcaaatg gtaaaacagc acgcttcatg acccagtatg
     3421 atacaaaaac cctcctattt acagtggatt cagaggatat gggtcaaaaa gttacaggtt
     3481 tggcagaagg tgcaattgaa agtatgcata atttaccagt ctctgtggcg ggcactaagc
     3541 tttcgaatgg aatgaacgga agtgaagctg ctgttcatga agtgccagaa tacacaggcc
     3601 cattagggac atccggcgaa gagccagccc cgacagtcga gaagccagaa tatacaggtc
     3661 cattagggac atccggtgaa gagccagctc caacagtcga gaagccagaa tacacaggcc
     3721 cactagggac atccggcgaa gagccagccc cgacagtcga gaagccagaa tacacaggcc
     3781 cactagggac agctggtgaa gaagcagctc caacagtcga gaagccagaa tttacagggg
     3841 gagttaatgg tacagagcca gctgttcatg aaatcgcaga gtataaggga tctgattcgc
     3901 ttgtaactct tactacaaaa aaagattata cttacaaagc tcctcttgct cagcaggcac
     3961 ttcctgaaac aggaaacaag gagagtgacc tcctagcttc actaggacta acagctttct
     4021 tccttggtct gtttacgcta gggaaaaaga gagaacaata agagaagaat tctaaacatt
     4081 tgattttgta aaaatagaag gagatagcag gttttcaagc ctgctatctt tttttgatga
     4141 cattcaggct gatacgaaat cataagaggt ctgaaactac tttcagagta gtctgttcta
     4201 taaaatatag tagattgaaa taagatgtga acaactctat caggaaagtc aaattaattt
     4261 atagaaaaat tttagcagtc aaggtgtact gttatagatt caatatatta tgcgactatt
     4321 aaccttgtct tctcctaaaa ttgactttct tgttttctta tcttgtccac tcgaaacaag
     4381 tattgtaaga atttgattat ttttgaaagt acttttaata tacttgatat agttaaaaaa
     4441 gatttgaaac taaattccaa attagaaaaa gacttgaaat actaaaaaaa aaaagtatac
     4501 tctaattgaa aacggtaaca aaactaattt agagaatgaa atatagagta tttctctctt
     4561 aaaagttttt ggtgaaacga gatgtagaaa ggagatttag ccaaagagtc tattagtgct
     4621 agaataatag attagaatta ttttagaaaa acgaagtgag cagcttataa attcaagtcc
     4681 ccaaatagat tcatactagt atcttttgca aaaaataaag ggcgacttcc ttcatgaata
     4741 tcaatttcat ctataaggaa ggtagctaat tgaactaact tatttattct gtttgtcgct
     4801 agaaaaatca gacctccttg tgaagattga ggagatactg aatgaaaatc aaagaagaaa
     4861 ctagcaagct agtagcagat tgcccaaaac accgctttga ggttgtagat aagactgacg
     4921 tatataatcc aaggtgaagc gactgtggtt tgaagagatt ttcaaagagt ataggctaga
     4981 gagtagtgtt tttatgtcct tctagtagaa aatgctagac agaagaatgg ggaacttgga
     5041 taggaaaaat agattgagaa aggaggttag aagagatgat tattacaaaa attagccgtt
     5101 taggaactta tgtgggagtc aatccacatt ttgcaacatt aatagatttt ctagaaaaaa
     5161 caggactaga aaatttaaca gaaggttcga ttgctatcga tggtaatcga ttgtttggga
     5221 attgctttat ttatctagca gatggtcaag caggggcttt ctttgaaaca caccaaaaat
     5281 atttggatat tcatttagtt ttggaaaacg aagaagccat ggctgttaca tcgccggaaa
     5341 atgtaagcgt tacccaagaa tatgatgaag agaaagatat tgaattatac acagggaaag
     5401 tggaacagtt ggttcatttg agagctggtg aatgcctcat cacttttcca gaagatttac
     5461 atcaacccaa ggttcgtata aatgatgaac ctgtgaaaaa agttgtcttt aaagttgcga
     5521 tttcttaatg tagaaagaga agaacgatga aaaaaatgag aaagttttta tgtctagctg
     5581 gaattgcgct agcggctgtt gccttggtag cttgttcagg aaaaaaagaa gctacaacta
     5641 gtactgaacc accaacagaa ttatctggtg agattacaat gtggcactcc tttactcaag
     5701 gaccccgttt agaaagtatt caaaaatcag cagatgcttt catgcaaaag catccaaaaa
     5761 cgaaaatcaa gattgaaaca ttttcttgga atgacttcta tactaaatgg actacaggtt
     5821 tagcaaatgg aaatgtgcca gatatcagta cagctcttcc taaccaagta atggaaatgg
     5881 tcaactcaga tgctttggtt ccgctaaatg attctatcaa gcgtattgga caagataaat
     5941 ttaacgaaac tgccttaaat gaagcaaaaa tcggagatga ttactactct gttcctcttt
     6001 attcacatgc acaagtcatg tgggttagaa cagatttgtt aaaagaacat aatattgagg
     6061 ttcctaaaac ttgggatcaa ctctatgaag cttctaaaaa attgaaagaa gctggagttt
     6121 atggcttgtc tgttccgttt ggaacaaatg acttaatggc aacacgtttc ttgaacttct
     6181 acgtacgtag tggtggagga agcctcttaa caaaagatct taaagcagac ttgacaagcc
     6241 aacttgctca agatggtatt aaatactggg ttaaattgta taaagaaatc tcacctcaag
     6301 attctttgaa ttttaatgtc cttcaacaag ctaccttgtt ctatcaagga aaaacagcat
     6361 ttgactttaa ctctggcttc catatcggag gaattaatgc caacagtcct caattgattg
     6421 attcgattga tgcttatcct attccaaaaa tcaaagagtc tgataaagac caaggaattg
     6481 aaacctcaaa cattccaatg gttgtttgga aaaattcaaa acatccagaa gttgctaaag
     6541 cattcttaga agcactttat aatgaagaag actacgttaa attccttgat tcaactccag
     6601 taggtatgtt gccaactatt aaggggatta gcgattctgc agcctataaa gaaaatgaaa
     6661 ctcgtaagaa gtttaaacat gctgaagaag taattactga agctgttaaa aaaggtactg
     6721 ctattggtta tgaaaatgga ccaagtgtac aagctggtat gttgactaac caacacatta
     6781 ttgaacaaat gttccaagat atcattacaa atggaacaga tcctatgaaa gcagcaaaag
     6841 aagcagaaaa acaattaaac gatttatttg aggctgttca gtagatgtaa aagactagaa
     6901 aataggtggg ctagtgatct gaaaagctct agcccaattt tgtaaaagaa gggagaagga
     6961 gaatggttaa agaacgtaat ttaactcgct ggatatttgt tttgccagct atgattatcg
     7021 taggattact ctttgtttat ccgtttttct cgagtatttt ttatagcttt accaataagc
     7081 atttgattat gcctaattat aaatttgttg gtttggctaa ctataaagct gtgctatcag
     7141 atcccaactt ctttaatgcg ttctttaatt caattaagtg gaccgttttc tcattagttg
     7201 gtcaagtttt agtagggttt gtgttggctt tagctcttca cagagtacgc cacttcaaga
     7261 aattatatag gaccttattg attgttcctt gggcatttcc taccatcgtt attgccttct
     7321 cttggcagtg gattctaaac ggggtttatg gctacttacc taatctaatc gtaaaattag
     7381 gtttaatgga acatacacct gcatttttga cagatagtac atgggcattc ctatgtttgg
     7441 tgtttatcaa catttggttt ggagcaccaa tgattatggt taatgtgctt tcagctttgc
     7501 aaacagtacc agaagaacaa tttgaggctg ctaagataga tggtgcttca agttggcagg
     7561 tgttcaagtt tatcgtcttt ccacatatta aagtggttgt aggacttcta gttgttttga
     7621 gaactgtatg gatctttaat aactttgaca ttatctacct cattactggt ggtggaccag
     7681 ccaatgctac aacgacgctt ccaatttttg cttacaacct gggttgggga actaaattgt
     7741 tgggtcgtgc ttcagcagtt acagtattgc tctttatctt cttggtggcg atttgcttta
     7801 tctactttgc tatcatcagt aagtgggaaa aggagggtag aaaataatga agaagaaatc
     7861 cagtatttat ttagatattc tctcacatgt acttttagtt ggtgcgacca tcgttgcagt
     7921 tttcccattg gtatggatta tcatatcttc tgtcaaaggg aaaggggaat taactcagta
     7981 tccaacacga ttttggcctg aacagtttac attagattat ttcactcatg ttatcaacga
     8041 tttgcacttc attgataaca ttcgaaacag tttaatcatt gccttggcta caaccctcat
     8101 tgcgattatt atttctgcta tggcagccta tggtattgtt cgattctttc ctaaattggg
     8161 agcaatcatg tcgagactac tcgtcattac ctatattttc ccaccaattt tgttagcaat
     8221 tccctattca attgccattg ctaaagttgg gttaacaaat agtttatttg gcttgatgat
     8281 ggtttatcta tcttttagtg ttccatatgc agtttggctc ttagttggat ttttccaaac
     8341 agttccaatt ggaattgaag aagcggctag aattgatggt gcaaataaat ttgttacgtt
     8401 ttataaagtt gtgctaccga ttgtagcacc aggtattgta gcaacagcta tttatacatt
     8461 tatcaatgct tggaatgaat tcctgtatgc cttgattttg attaacaata caggaaagat
     8521 gacagtagca gtagcccttc gttcacttaa tggttcagaa atactagact ggggagatat
     8581 gatggcagcg tctgttattg tagttcttcc atcaattatt ttcttctcta tcatccaaaa
     8641 taagattgca agtggattat cagaaggatc tgtgaagtag acgaaagaag gaaaaaaatg
     8701 aataaaagag gtctttattc aaaactagga atttctgttg taggcattag tcttttaatg
     8761 ggagttccca ctttgattca tgcgaatgaa ttaaactatg gtcaactgtc catatctcct
     8821 atttttcaag gaggttcata tcaactgaac aataagagta tagatatcag ctctttgtta
     8881 ttagataaat tgtctggaga gagtcagaca gtagtaatga aatttaaagc agatgaacca
     8941 aactctcttc aagctttgtt tggcctatct aatagtaaag cagactttaa aaataattac
     9001 ttttcaattt tcatgagaga ttctggtgag ataggtgtag aaataagaga cgcccaaaag
     9061 ggaataaatt atttattttc cagaccagct tcattatggg gaaaacataa aggacaggca
     9121 gttgaaaata cactagtatt tgtatctgat tctaaagata aaacatacac aatgtatgtt
     9181 aatggaatag aagtgttctc tgaaacagtt gatacatttt tgccaatttc aaatataaat
     9241 ggtatagata aggcaacact aggagctgtt aatcgtgaag gtaaggaaca ttacctcgca
     9301 aaaggaagta ttgatgaaat cagtctattt aacaaagcaa ttagtgatca ggaagtttca
     9361 actattccct tgtcaaatcc atttcagtta attttccaat caggagattc tactcaagct
     9421 aactatttta gaataccgac actatataca ttaagtagtg gaagagttct atcaagtatt
     9481 gatgcacgtt atggtgggac tcatgattct aaaagtaaga ttaatattgc cacttcttat
     9541 agtgatgata atgggaaaac gtggagtgag ccaatttttg ctatgaagtt taatgactat
     9601 gaggagcagt tagtttactg gccacgagat aataaattaa agaatagtca aattagtgga
     9661 agtgcttcat tcatagattc atccattgtt gaagataaaa aatctgggaa aacgatatta
     9721 ctagctgatg ttatgcctgc gggtattgga aataataatg caaataaagc cgactcaggt
     9781 tttaaagaaa taaatggtca ttattattta aaactaaaga agaatggaga taacgatttc
     9841 cgttatacag ttagagaaaa tggtgtcgtt tataatgaaa caactaataa acctacaaat
     9901 tatactataa atgataagta tgaagttttg gagggaggaa agtctttaac agtcgaacaa
     9961 tattcggttg attttgatag tggctcttta agagaaaggc ataatggaaa acaggttcct
    10021 atgaatgttt tctacaaaga ttcgttattt aaagtgactc ctactaatta tatagcaatg
    10081 acaactagtc agaatagagg agagagttgg gaacaattta agttgttgcc tccgttctta
    10141 ggagaaaaac ataatggaac ttacttatgt cccggacaag gtttagcatt aaaatcaagt
    10201 aacagattga tttttgcaac atatactagt ggagaactaa cctatctcat ttctgatgat
    10261 agtggtcaaa catggaagaa atcctcagct tcaattccgt ttaaaaatgc aacagcagaa
    10321 gcacaaatgg ttgaactgag agatggtgtg attagaacat tctttagaac cactacaggt
    10381 aagatagctt atatgactag tagagattct ggagaaacat ggtcgaaagt ttcgtatatt
    10441 gatggaatcc aacaaacttc atatggcaca caagtatctg caattaaata ctctcaatta
    10501 attgatggaa aagaagcagt cattttgagt acaccaaatt ctagaagtgg ccgtaaggga
    10561 ggtcaattag ttgtcggttt agtcaataaa gaagatgata gtattgattg gaaataccac
    10621 tatgatattg atttgccttc gtatggttat gcctattctg cgattacaga attgccaaat
    10681 catcacatag gtgtactgtt tgaaaaatat gattcgtggt cgagaaatga attgcattta
    10741 agcaatgtag ttcagtatat agatttggaa attaatgatt taacaaaata aaggagaaaa
    10801 acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg gctcgctaca
    10861 tgcaaaagaa tgatggagca gagattactc ttctctatga tccagataat gcagaggcga
    10921 ttgcagaaga attgggggca aaagtagcaa gttccttaga tgagttggtt tctagcgatg
    10981 aagtagattg tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg
    11041 ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt
    11101 gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta
    11161 tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag
    11221 acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaaccg tcagtatcat
    11281 ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt
    11341 gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg
    11401 cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt
    11461 ctaataagcg ttttgccttg ttagaatggg gttcagctta tcgttggggt gaacattatg
    11521 tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc
    11581 ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg
    11641 atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag
    11701 gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg
    11761 agattatgga aggagctcca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg
    11821 ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag
    11881 taaaattgtc agaaattgta aaataaattt tggtattctc ctattatagg tcgacttgct
    11941 cctctgaaag tacttttaga ggagctgttt gactttgcta gtttttgaaa ctgaaatcta
    12001 ttatactaca aactattgaa agcgttttaa ttttaaggta taataatctc atagaaataa
    12061 agaaaaggag gaaagaggat g
//
LOCUS       DAVBOM010000058        12027 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBOM010000058 DAVBOM010000000
VERSION     DAVBOM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.058"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..207)
                     /locus_tag="VQ878_001793"
     CDS             complement(<1..207)
                     /locus_tag="VQ878_001793"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096096.1"
                     /translation="MENMTNHLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFF"
     gene            complement(275..916)
                     /locus_tag="VQ878_001794"
     CDS             complement(275..916)
                     /locus_tag="VQ878_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096097.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(918..2947)
                     /locus_tag="VQ878_001795"
                     /pseudo
     CDS             complement(918..2947)
                     /locus_tag="VQ878_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(3216..4115)
                     /locus_tag="VQ878_001796"
     CDS             complement(3216..4115)
                     /locus_tag="VQ878_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3096098.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ878_001797"
     CDS             complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ878_001797"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET3096099.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(4747..5520)
                     /locus_tag="VQ878_001798"
     CDS             complement(4747..5520)
                     /locus_tag="VQ878_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET3096100.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(5825..6718)
                     /locus_tag="VQ878_001799"
     CDS             complement(5825..6718)
                     /locus_tag="VQ878_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET3096101.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGRSDANANAGGGSQAGGPVHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVAVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ878_001800"
     CDS             complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ878_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET3096102.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(7281..8495)
                     /locus_tag="VQ878_001801"
     CDS             complement(7281..8495)
                     /locus_tag="VQ878_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3096103.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(8651..8944)
                     /locus_tag="VQ878_001802"
     CDS             complement(8651..8944)
                     /locus_tag="VQ878_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096104.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9106..9558
                     /locus_tag="VQ878_001803"
     CDS             9106..9558
                     /locus_tag="VQ878_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET3096105.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(9593..10981)
                     /locus_tag="VQ878_001804"
     CDS             complement(9593..10981)
                     /locus_tag="VQ878_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3096106.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            11047..12009
                     /locus_tag="VQ878_001805"
     CDS             11047..12009
                     /locus_tag="VQ878_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET3096107.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT         3435 a         2823 c         2193 g         3576 t
ORIGIN      
        1 aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc
       61 cacatcatcc actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg
      121 cctttgccct tcactactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
      181 aaggagatga ttggtcatat tttccatgat gaggatatct tataaaccac ctctggcact
      241 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
      301 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
      361 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
      421 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gttttcgcaa
      481 gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat
      541 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
      601 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
      661 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
      721 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
      781 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
      841 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
      901 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
      961 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
     1021 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
     1081 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
     1141 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
     1201 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc tacccgtttg
     1261 tcatttagta ccttggcaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
     1321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
     1381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
     1441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
     1501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagacttac ctgtgggagg tagtatttct
     1561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
     1621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
     1681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
     1741 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
     1801 ctaggtccac ttctgctccg tctgagaaat tgtcaacatt gctcataata taaaaagagt
     1861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
     1921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
     1981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
     2041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
     2101 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
     2161 caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
     2221 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa gacaccttga taccagagaa
     2281 tccccaatcc caaaagactg gataccagca ctgagtagat aaactgtctc acatcttcta
     2341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
     2401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
     2461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
     2521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
     2581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
     2641 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
     2701 agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
     2761 ctaccgccaa gtgactcaaa acctctgtca cctcttcgcg actagctact ggttgattta
     2821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
     2881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
     2941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac
     3001 tgcgatgtta agaagcttat taagttcttt ctactagcaa catcttcaaa tacattatat
     3061 ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacca tttcgtgtca
     3121 tttttagctt atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg
     3181 agaacaagga catttttgtc actgattcac tatgtttata aatatttttt gacatcctct
     3241 tgccattcct ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt
     3301 ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc
     3361 ttccacaaaa acataaatac aagaggtttc ttttgataat cttgagtttt atccataatt
     3421 tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa
     3481 cacattcctg aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt
     3541 ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct
     3601 tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa
     3661 acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc
     3721 cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa ttgttcttct
     3781 ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg
     3841 tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa
     3901 gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga
     3961 gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt
     4021 tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat tcctttttct
     4081 atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt
     4141 cgaaaaatac tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt
     4201 tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt
     4261 gcttgccgtt ggaatagccg attcggagag tctctccgag atattctcta cgcttacggc
     4321 tgtctgcccc tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac
     4381 tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg
     4441 catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct
     4501 tgagaaaggc atgctgaact gttggaatga ccgtcatgat catgcgccga atccgttccc
     4561 cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgcagg cgctgaatcc
     4621 gctctatatc ctgatcattg atggcagaac ctcgagtctc ataggtctcc acatcgaaat
     4681 aacgcttgag attgaccgta tcatcacgcc cttcaaccac aattacttgg gaaattttct
     4741 ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc
     4801 tagctcttct gtcgtcatac cacgcaagtc agcgataaag tcgaccacat agcgagtata
     4861 ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg catctgtttc
     4921 caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt
     4981 gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca
     5041 ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt
     5101 gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa
     5161 gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt
     5221 catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat gttttaactt
     5281 atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc
     5341 aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct caatcgtcgg
     5401 tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc
     5461 ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat
     5521 ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt
     5581 ttcggtttcc cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt
     5641 gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat agaatattcc
     5701 tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat cactaggatt
     5761 gatgacttct caaaatcccc cttataatct aactttaagt agagaataga attttctagc
     5821 tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca
     5881 ctagaccaag actagcaagt gctgcacttg atgctgaacc tgtgttaggt aattgtttgc
     5941 cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg
     6001 ttgtcttagg agcagcatta ggagccactg gtctcttagg aactgcaacc atggcaatgg
     6061 cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca ttttcaatct
     6121 ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct ttttctttat
     6181 cagaaagcgg tgcgcctttg atttcatcct gcttgttctt ggctgctttt tcaatggcat
     6241 ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga gctgagtttt
     6301 gtgaacctgt gtgaactggt ccacctgcct ggctaccacc gcctgcattc gcattagcat
     6361 ctgatcttcc agtattgcct cccttatctc cacctggtgt agtttctagc ttatactctg
     6421 gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta tcttttccta
     6481 gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatct ccagctacat
     6541 tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt
     6601 cttcatctgt taaatgagtt atatctttta catctactct ttgagcaggt gctttaacag
     6661 ttgatttttc agcagtcggt ttagtactat cttgtgcttt tggatcttgt gctaccaatt
     6721 gatttcctgg aattgtaata gctgaaccat ctttaaagac gattgtcgct gtaccatctc
     6781 cagctacttc aactttatag taaaataaaa taataacagg acaaatcgat caggacagtc
     6841 aaatcgattt ctaacaatgt tttagaaaca gaggtgtact attctagttt caatctacta
     6901 taacatcgct tccgaatcca tttgcatcta ctgaactttt ttacaaaaat aaaaatcagt
     6961 agactcgagt tcctactgat ttttgataga attcgtttgg attatgcagc caaaactttg
     7021 cgtcctttac gacgacgagc tgccaatacg cgacgaccat ttttagttga catacggtta
     7081 cggaatccgt gtttgcgcgc acgacgaagt ttacttggtt gataagtacg tttcacgatg
     7141 aatacctcct catagatttt gtattcgttt agccggctat aaagtgatca gttactaaac
     7201 atactttact attctatctg attctttcac ttttgtcaat agctctaggc aaatgtttcc
     7261 agctttttcg aatgcaagcc ctatctacga tactgtttca agaaacgagt catcttttct
     7321 tggatttggg ctaactcatc aacacgagga aggtaaacga tacggaagtg gtctggttcc
     7381 tgccagttaa agcctcgacc atgaaccaag agaacctttt cctgcttcaa gaaatcaagg
     7441 acaaactgct catcatcatc gatacggtac atattgcggt cgatttttgg gaagatatag
     7501 agccccgcct tgggtttaac ggcagacaaa cctggaatat cttgaatggc attatagatg
     7561 aaatttcttt gctcgtagat tcgtccacca ggaagaagca attcatcgac tgattggtga
     7621 ccccccaagg aagtttgtac gacttgttgg gccaaaacgt tagagcaaag gcgcatattg
     7681 gacagcatat tgagcccttc gatatagccc ttaacatgag tcttagggcc agacaagacc
     7741 atccaaccca cacggaaacc tgctatgcgg tgggattttg acagaccatt catgctgaca
     7801 cagaagacat ctggtgccaa gctcgccaca ggcgtatgca catgtccgtc cattaccatg
     7861 cggtcataga tttcatccgc aaagataatc aaatcgtttt gacgggcaat ctcaataatc
     7921 cccagcaaga gttccttagg ataaagggct ccagttgggt tatttggatt gataaggaca
     7981 attgccttgg tattggaagt gatttttgac ttgatatcgt caatatctgg gtaccattcc
     8041 acagcttcat cacagatata gtgaacggca tttcctccag ctaggctgac agccgccgtc
     8101 catagaggat agtctggcat tggcactaag acctcatccc cattgtccaa aagcccctgc
     8161 atggacatga caatcaactc actgacacca tttccaaggt aaatatcatc aatatctacg
     8221 tttgggaatt tcttcagctg gcaatactgc atgatggcct tacgggctga gaaaatccct
     8281 ttggagtcag aatagccttc actatcacgc gcattcataa tcaagtcatg aatgacctcg
     8341 tctggcgctg taaagccaaa ttctgctgga tttcctgtat tcagacgtaa aatcttttct
     8401 ccattcgctc gcatccgcat ggcttcttcc aatacaggac cacggatatc ataagcaaca
     8461 tgctctaact tactagactt gttatattct ttcatcttgt ttcctcaatt catcaggata
     8521 gtaacattat accactagaa agagaatgcg acaagtttac tgaaatgtgt tactagtttc
     8581 gtatagaaga aaaaccttgc taaaggcgag gttaagaacg tagagatagc aggtattttg
     8641 caaagacaca tcacatacca aaagataaac ctagaaaaag caagcctaga aaggagtcat
     8701 aaagaagatt aaacatgagg aaaagccccc atatcatcaa gtaatcccaa cgcccacttc
     8761 gttttgcaac tagaaataag attagatggt agagtacatg aaagactaaa aatccaataa
     8821 aacctggata aataagcggt accaaactct ctaattgcca gatcatgatc acttctacca
     8881 agactgaaac taggataatt ccataataca ggaaatttga tttttgaaaa gagtttttca
     8941 tcattctccc ttccttcact tctttcctgc tatcctttct tttattttat catatattta
     9001 tatagatttt aagccctaat attcttttga aaaatacttt ttttgcttta cttctatagt
     9061 gaaaaggttt acaattatag taagaaaatt tcaggaggtt tcattatggc acaacgttac
     9121 caaaatatca tggtcgcaat cgatggttct aaggaagcgg acttggcttt tgtcaaggga
     9181 gttcattctg ctctacgaaa cgacgctaaa ctcaccatcg tacatgtcat tgacacacgc
     9241 gctctccaaa gcgtatccac ctttgatgct gaagtttacg aagaactcca agtcgacgct
     9301 gaaagtctga tgaaagagta cgaaaaacgt gctaaagatg ctggggtagc agatgttcat
     9361 atcgtcattg aaatgggaaa tccaaagacc ctgctagcac gtactattcc agatgccgag
     9421 gaagtggacc tcatcctcgt tggcgcaact ggtctcaacg cctttgaacg cctcttagtc
     9481 ggctcttcat ctgaatacat actccgccat gctaaggtcg atttgctggt tgtgagagaa
     9541 caagaaaaaa ccttataatc acaaagaaaa ggagccccta gctccttttt gtttacgatt
     9601 tatttctctc tttatggcgt tcgtaagcct tgagctggcg ctgcagttcc tttttaatag
     9661 caggttctgg agcatatttt tcttcccaat tatctggttt taagatttta tgggtcactg
     9721 gatcaaaatg agccttgcca tctggaaaaa ttttccccat attggcctga tggacaatat
     9781 caaaaatacg ttctgggtcc acccccatca agacaaaact gccgtaggtg aagtaaagcg
     9841 tgtcaatcaa ggcatccact tgccctatca aatcttgctg agcaggtgtc ttcttggcta
     9901 ctttacctgc tgccttatca agggcctgat gaagttgcga tacagcttga ccaaaatctt
     9961 cttcagaagg actggctgct cgaacaaact ccaccaattc ttctatttta aaaccagccc
    10021 tatgggttgc accctctaaa tcccaagctc gaggttcttc ttgggttcgt tcatccatca
    10081 tgtggtggaa ggtcttgacc ttattgaaat gatagtcacg gctgacaaag actttttctg
    10141 aagacaaaac accaaaatgt tccaaggcct tgtggatccc atcttgttga ttgctagtgg
    10201 taatgtgctt ggcagcttcc ttgacactgc tactaccatt tcccatagcg accgacatac
    10261 cgacgccagc cagcatttca aggtcattat ctgagtcacc aaaagccatg acttggttga
    10321 ggtcaaagcc atattctttc ccaactcggc gaatgccttc taatttagaa tttccctgat
    10381 tgatgacatc cgatgcaaaa ggattgctac gtgtcaattt caagtcttca aaatcagctg
    10441 ccgccttctc agattcttct ggtgtcatca gcatcaaaac ttggtagata ggctgattca
    10501 tcaggtgaag caggtcctct tccttttggg gaacaacctt gctgaccatg cgattaaaag
    10561 actgactcac cgtccgagtt aaaacagagg gaacgaagcg actaattcgt tgggaaaaag
    10621 aacccagacc aaaggacatg attttagaac ccaacatggc atccttggtc cctagagcaa
    10681 tctccgtgcc ctctttttta gcatagctaa ttagatggcg caaatgtaac ttggaaatag
    10741 ggctcgtgaa caagactctg tctttactaa agatatactg gccattatag gttaccgcaa
    10801 aatccagatc caaatcgtcc atcaattcct taacaaaaaa aggtcctcgt cctgtcgcta
    10861 cgccaactag taccccttgt tctttgacaa tcttaatcgc gtccttagtg gatttcaaaa
    10921 cactcttgcg attgttgacc aaggttccat cgatatcaaa aaaaacagct ttgacttcca
    10981 tcctattcca atctcccctt ttgtgataca atgattatac cacatttcag aaagagttag
    11041 taaatcatgc ctaagaaaat ccttgtttta catacgggtg gaactatttc catgcaggcc
    11101 gatgcttctg gcgctgttgt gacgagttca gataatccca tgaaccatgt gtccaaccca
    11161 cttgaaggaa tccaagtcca cgccttggac ttttttaacc ttccaagtcc ccatatcaaa
    11221 cccaaacata tgctggtcct ctaccagaaa attaaagagg aagcagataa ctacgatgga
    11281 gtggtgatca cacacggaac cgatacttta gaggaaacag cctatttcct tgataccatg
    11341 gaagttcccc atatgcctat cgttctaaca ggagccatgc gtagctccaa tgagctcggt
    11401 agtgatggtg tttataatta cctaagtgct ttacgagtgg ccagcgatga cagggctgct
    11461 gacaaaggag ttttggtcgt tatgaacgat gaaatccacg ctgccaagta tgtcaccaaa
    11521 acacatacga ctaatgtcag caccttccag actccaacac atggccccct cggtctcatc
    11581 atgaaacagg aaatcctcta cttcaaaaca gctgaacctc gtgttcgctt tgaccttgat
    11641 cacatacaag gtttagtccc tatcatctcg gcttatgctg gtatgacaga tgagctgatt
    11701 gatatgctgg atttagaaca cttggacggt ttgattatcc aagccttcgg agctggtaat
    11761 attcccaaag aaacggctca aaaattagaa agccttctgc aaaaaggaat cccagtcgct
    11821 ctggtatcac gatgctttaa cggtattgcc gagcctgttt atgcctacca gggtgggggc
    11881 gtacagttgc aaaaagcagg cgttttcttt gttaaagaac tcaacgccca aaaagctcgc
    11941 ttgaaactcc tcatcgccct caatgccgga ctaacaggac aggctttgaa agactatatg
    12001 gaaggctaat actcttcgaa aatctct
//
LOCUS       DAVBOM010000059        11716 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBOM010000059 DAVBOM010000000
VERSION     DAVBOM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.059"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ878_001806"
     CDS             complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ878_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET3096108.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ878_001807"
     CDS             complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ878_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET3096109.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2411..2905)
                     /locus_tag="VQ878_001808"
     CDS             complement(2411..2905)
                     /locus_tag="VQ878_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3096110.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2902..3366)
                     /locus_tag="VQ878_001809"
     CDS             complement(2902..3366)
                     /locus_tag="VQ878_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3096111.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3376..4710)
                     /locus_tag="VQ878_001810"
     CDS             complement(3376..4710)
                     /locus_tag="VQ878_001810"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET3096112.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4721..5338)
                     /locus_tag="VQ878_001811"
     CDS             complement(4721..5338)
                     /locus_tag="VQ878_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3096113.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5386..8484)
                     /locus_tag="VQ878_001812"
     CDS             complement(5386..8484)
                     /locus_tag="VQ878_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3096114.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELSDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLSGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8577..9743)
                     /locus_tag="VQ878_001813"
     CDS             complement(8577..9743)
                     /locus_tag="VQ878_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3096115.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9751..10845)
                     /locus_tag="VQ878_001814"
     CDS             complement(9751..10845)
                     /locus_tag="VQ878_001814"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3096116.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11003..11656)
                     /locus_tag="VQ878_001815"
     CDS             complement(11003..11656)
                     /locus_tag="VQ878_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3096117.1"
                     /translation="MFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYD
                     FNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMK
                     EGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYS
                     VLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
BASE COUNT         3252 a         2680 c         2220 g         3564 t
ORIGIN      
        1 aagtcagtaa ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtagcaaaa tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt
      121 tttaggctgt tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa
      181 tggttgctgt atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg
      241 aaaccttacc tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt
      301 cgtcctcacc aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa
      361 ctgcgtcgct attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc
      421 cttcgacaaa ggcttgttca tccttagctg cttcgtactc actgttttct gaaagatcac
      481 cgtatgaacg ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt
      541 cttctaattc tttttcaagt ttctcctttt cctcaagggt cataggatat gttttttctg
      601 ccatttttct caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca
      661 taattttagt ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg
      721 tcttcttgat tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg
      781 ttatcgctct tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact
      841 ggaccaggca tgagacctac atttttataa acattataag gtgaatcaat gtcggtatca
      901 atcgcaacat cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt
      961 gcaatattac tttgaagtgg catatcacga tttaaacgat tgtagaatac acctgcaatg
     1021 agcttacgat cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac
     1081 tcattgatag tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc
     1141 atagcagcta acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat
     1201 gtagctggga aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa
     1261 ctttccagta aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact
     1321 ttagccaaga aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca
     1381 gtttgagcaa tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt
     1441 tcttgcggtt catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata
     1501 ctcttttgca aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa
     1561 aaactaaaaa tcagaccatg ctttaccaaa ccagcttttt caagcgtcgt accgatttct
     1621 tgaacgtttg aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata
     1681 ggtaacaaag aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca
     1741 aggaatacaa ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggt
     1801 ttaacgggtt ttgctccttc tctacggcta cgacgtgatg tatcgctgat gatatccact
     1861 gtttctgtag caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc
     1921 gtataggaaa cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt
     1981 ctaacaggac ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct
     2041 tgacttggat gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct
     2101 ggtacacctt gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc
     2161 gttgacaagg aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact
     2221 actgcctcat cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga
     2281 atctgctctt taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc
     2341 tccttgttga taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac
     2401 ttttcctaac ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg
     2461 ttgactggga ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt
     2521 catgacaggt tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg
     2581 tcagcaattt ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca
     2641 cagagatata accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt
     2701 cttgcagatg gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt
     2761 tttcagcaac cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag
     2821 gaatggcttc ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt
     2881 ctaatcttgc ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat
     2941 actatagccc tggctagttg catagagcaa agttgcttct tcatcaacaa aaccgttcat
     3001 ttcaaaatag gaaagcagct catcaggact ctccaaacga atccctttgt aatccagatc
     3061 aactgccacc tctttcaagg ctgcaagaag aagtgttccc aagccctgtc tctgatggtc
     3121 agactcgatg actaaagaat gtacttttag atattgcgga ttgtctgact ggggacttga
     3181 taaaatatag cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt
     3241 acggatactt tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt
     3301 ctgaagtgcc cctatctcag gcaaatcaga cttgcttgcc tgaatgatct taattggaat
     3361 ttccatggga acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga
     3421 gtattcatag gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc
     3481 taggagcgga gaaacatttt caacagtaat cacttggtgt tttttgttga ttttgttggc
     3541 taggtcttct accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc
     3601 tagataaaca gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt
     3661 tcttgtaaag gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg
     3721 agccgcatcc aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat cgataatcac
     3781 tgtatcattg acaattttct cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg
     3841 ctcacgcacc aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc
     3901 attcatgata ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg
     3961 gaaatgaacg gtgaaggttg aaccagttgt tgaacgaata agatcactag ctacaaagtc
     4021 attgccttca gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa
     4081 ttcagcatct tcaccataga caaaaagacc cttggtgatt tgtttggcat agtcgttaaa
     4141 ggcattgaaa acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt
     4201 gataatagag tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa
     4261 gacaaaatat ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt
     4321 atctgtaatg tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc
     4381 tcctgctact cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg
     4441 tttatagctg ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa
     4501 ggcatttcca gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat
     4561 ggtaattcct gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc
     4621 ctgaaccttg tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt
     4681 aattccgata aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca
     4741 gattcaactc ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga
     4801 tttggctctt ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt
     4861 cattcttggt agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt
     4921 tttggctata tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat
     4981 tgccctgtct aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta
     5041 gatagttagc agagcgtttc tttttcaagt ctgcacgcgc ttcttcacgc gccacctccg
     5101 catagctctt tccttctttt ttaaccccta aaggagcttt tttaggtttc cctacttgct
     5161 tttcaatcgg ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat
     5221 ctcgatactc acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg
     5281 gcatttcagt caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt
     5341 tctatttcct ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc
     5401 agaaattccc aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc
     5461 gtccaatact tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc
     5521 aatggttccc ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg
     5581 ggcacggcca atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac
     5641 tgtatctgca cctgacaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc
     5701 atctctttct ccttgattaa aggccttggt catgtcttgt ctttccttgg ctggggttga
     5761 acccgtaatt ttaaaggaag tcaggcccaa gtctgacagt tcttgttcaa ttttttccaa
     5821 cattcccttg aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag
     5881 taggtctcgg agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc
     5941 aggagtgtca catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg
     6001 ctgaaattcc tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag
     6061 gtaaatagcc ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg
     6121 caattcagtc agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc
     6181 cactcgctct gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac
     6241 gatttggaaa atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc
     6301 aaagaccgac ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt
     6361 catgacctga gcctcatcta agaaaaggaa gtcaaaggcc atcccctgat aaaactcact
     6421 gtcctgacgg aaggtggcat agctagtcac atagatttga tggctctcgg caagaatctc
     6481 ctcacgactt gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg
     6541 aaactcatcc gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc
     6601 ttttgtcact tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc
     6661 atcagccaaa atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt
     6721 ttcctgataa tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg
     6781 atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc
     6841 ttcaaagaga tgagctaaac tgtaggccaa ggatttccga gcctgcaagg tcccatcttt
     6901 taattcaaat tgccccagtt cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa
     6961 aaagtaaact tgattagacg aatcaatata aaaatcctga ttggcaacca aggcctgcat
     7021 ggcttggtcg atttcctcct gggcaatatt ttgaaaatca aactggattt ccaagagacc
     7081 tcccttggag gcaatctgca cctgaggact cgctaggcta taaagctctt ctagtttatc
     7141 tgataggtca acatgcccga gtttttcaaa gactggaatg atatcatgaa aaaaatgata
     7201 gacagactcc gcttttaagg cctgacgcca agattgaaaa tcggcttcaa agcccgcagc
     7261 caaacagact tggaaaattc tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc
     7321 tagctcttgt cggctagata cctgtctatt tccataatca aactgaattt ctaaacgaat
     7381 ccgattatct tcttccctgt caaagtaaaa agagggcgca aaagttttga tttgtagacg
     7441 ttctggagct gaaacggtgc ccatctggat aaaaagagtc agacaggagg ccaatttgtc
     7501 tcgatcactg ctatcaaatt gcaggtattt ctttccttgt tgacccacag gtaacgcttt
     7561 aatttccttg agaagacgca tctgctggtc tgttaaaaaa taaacctgac ctttatggaa
     7621 aagtactgct ccctgataaa agacattgac cctaggactc tcactgattt ccatttcaaa
     7681 atagtccgag tattctgtta ctgtaaaggc aaatagattg gcatcagcat gcatatcctg
     7741 aaaaagcagg gtttggtagc tatccacttg atggtcaaat tgaaaatggg gcaaggccat
     7801 cagtaaattc acaccctgct caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt
     7861 ttggaaaaag aggtctggaa ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag
     7921 ttcttggctg gcatcatcaa aggcttccca agaaagagac tcctcataaa tcttgccaat
     7981 catatacgac tttctctgct cgacaatcct taaaaaaagt ggaatatccc gaatgacata
     8041 gtatttttgg ctattgattt ggccgattct cagagtccac aagatatgat tggttcctgc
     8101 ttccacctga cccacagctg ataactcata ggcgcattct gattttggag ataaaattcg
     8161 attcaaaaac ttgccaccca aggtcacctt ggtttcaacg gcctcttttt cttcatgacc
     8221 ttcttccaga ctccacaaga tttcctgacc acgctcatca tttttcagaa aatgctctag
     8281 cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa tcacaggcac aaaaaaccaa
     8341 atcatcctct aaactatagc gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt
     8401 cttttccttg atgatatcaa ccttaccagt ttcataaagg gcaacacctt cgatacgaat
     8461 tttccccgga atcaatttag ccatattttc acctttacct tatcttttta ttataccata
     8521 ttttcgccta tgaaaatagc cttctaggaa gacttttctc ctagaaggct ggatttttaa
     8581 cgtttggcaa aagtagccac aatccgctga cagacttctt gcaacagaga tttgggcata
     8641 gctatattga tgcgggcatg gagacttcct tcctctccaa aatccaaacc acggttgagg
     8701 ataaccttgg cttcatttct caacaactct tgcaatgttt catcagtcag gtcataggct
     8761 gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca tgaccttgat tttagtctct
     8821 tttccaaata gatccaccac ataattgatg tggtcttcaa agacttgctt gagttcctct
     8881 agccaatctt taccgtatcg ataggcagct tctgtcgcca aataacccaa gcctgaaatt
     8941 tcatgctgat tattggccaa caggcgtttc tggaaagcca gtctcaactt aggattttca
     9001 atgactgcat aggaattttt tgttccagca atattaaatg ttttagtggc actgctcaag
     9061 acgatagcaa aatttttgaa ggcaggattg atggtattga aagactggtg tttgtgacca
     9121 aagagggtca aatcttggtg aatctcatcc gaaactaaca aaacaccgtg tttttggcaa
     9181 agttggccaa tcttctccaa cacttctttt tcccaaacac gtccaccagg attgtgaggg
     9241 ttgcaaagaa tatagagttt aacctcctct tccaccaaat ccttttcaag ttggtcaaag
     9301 tcaatctcaa acagaccatc cttttccact aaggaattag taatcaatct acgattattc
     9361 aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt taattaaaac cgcctcgcct
     9421 tcttttgtaa aggtttgaat agctgttgag atggctggta ccacaccctc gataaagaca
     9481 agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt cccacttttg aatttcctta
     9541 attaagtctt cactggcata ggtataacca taaaccagtt ggtctgcgta agtttgcacg
     9601 gcttggcgga tttcaggcaa gaccacaaag tccatatccg ctatccaagc tggtagaact
     9661 tcactatccg tttctgtttc tttccattta taggtatggt gccctaaacg gttgggcagg
     9721 cttgtaaaat catattttcc catctttgtc ttatccttct aaggcttggc gcaaatctgc
     9781 aatcaaatct ctagcatcct caatcccaat agacaaacgc aagaggtcat ctgtcaaacc
     9841 ataagaatgg cgtacttctg ctggaatatc agcatgagtt tgagtcgttg gataagtaat
     9901 aagactttcc actccgccca aactttccgc aaaagagaag accttgagac tgttcaaaat
     9961 atgaggaatg cgtgtttcat cggctacttt aaaggaaatc atgcctccac gaccagtgta
    10021 gagaacttcc ttaactgctg gagaatcctt caaaaaggca accacttctt gggcgttagc
    10081 tgttgagcgc tccatacgaa gagataaggt cttgagacca cgaagcaact ggtagctgtc
    10141 aaatggagac aagactgccc ctgttgtatt gagattgtaa aaaagcttct cgtatagttc
    10201 taaactattg gtcacaacca ctccagccaa gacatcattg tggcctgcta gatacttggt
    10261 tgctgaatgg agaacgatat ctgctccatc ttcaatcgga cgttggtaga tagggctata
    10321 gaaggtattg tccaccacca ctttggcacc cttagcatga gccaattttg ctagtttttc
    10381 gatatcaaat tccaacatca agggattggt tggggtttcg atatagagaa catccacatc
    10441 cttttctaac tcggcaatca actcttcttc tgtattggca taggtaaaat ggaaacgacc
    10501 ttcctgctcc acttggttaa accagcgaaa agaaccaccg taaagatcac gcactgccaa
    10561 gaccttactt cctactggaa agacgctaaa ggccagtaca atagctgaca tccctgagct
    10621 agtcgctagg gcatagtctg ctgactcaat agccgccaag acttcctcag ccttactacg
    10681 agttggattt ttagtgcgcg tatagtcaaa cccagtagat cgaccaaact ctggatgctg
    10741 ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct gtcgcttcat ctgacttaat
    10801 acccgcctgg gccaaaattg tgttaatgtg taattccttg ctcatacaat acctccaaat
    10861 ctatagtaac tattgtacca cttattttca tcaactcatt ttcttctttt caagagctag
    10921 ttatagtttc aaactatata aaaagggagt ttttcctgct ccctttaata gactataaaa
    10981 tggtgaatct caaaagacac cttcactcta tcatttgctc ctgcacaaaa cgagcataac
    11041 gctcatgatt ttccagtagt tccttatgag ttcctgagcc agtgattttc ccctcctcta
    11101 agaagaaaat acaatccaca tcttttaccg ttgacaaacg atgcgctata atcacaaccg
    11161 tcttctcctt taatacagaa tagaggctac tgataatcgc atactcagaa tccgcatcaa
    11221 gattagcagt ggcttcatca aatataagaa tttcagcatc ttttaagtag gctctagcta
    11281 tttgaagtct ttggctttgc ccccctgaca agagtcgtcc gcgttcacca acttcagtat
    11341 ctagtccctc tttcatggag cgaatctcat cacctagtga tactaagtct agcactttca
    11401 tcaattcatc atcagttact aagcgattca aaccgagaca aagattgtca cgaatactgc
    11461 cagataagac tgcattattt tgtgaaaccc aagcgatttt acttctccat tcttttaagt
    11521 taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt ttataaaacc
    11581 gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca aaagcaattt
    11641 tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt tcatcataac
    11701 caaaatagac atggtt
//
LOCUS       DAVBOM010000060        11592 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBOM010000060 DAVBOM010000000
VERSION     DAVBOM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.060"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1043)
                     /locus_tag="VQ878_001816"
     CDS             complement(<1..1043)
                     /locus_tag="VQ878_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3096118.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQR"
     gene            1666..1848
                     /locus_tag="VQ878_001817"
     CDS             1666..1848
                     /locus_tag="VQ878_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3096119.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1858..2208
                     /locus_tag="VQ878_001818"
     CDS             1858..2208
                     /locus_tag="VQ878_001818"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3096120.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            2216..3406
                     /locus_tag="VQ878_001819"
     CDS             2216..3406
                     /locus_tag="VQ878_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3096121.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3921..4913)
                     /locus_tag="VQ878_001820"
     CDS             complement(3921..4913)
                     /locus_tag="VQ878_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3096122.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            5073..6827
                     /locus_tag="VQ878_001821"
     CDS             5073..6827
                     /locus_tag="VQ878_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096123.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFFAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6811..8532
                     /locus_tag="VQ878_001822"
     CDS             6811..8532
                     /locus_tag="VQ878_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096124.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILINGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8543..9127
                     /locus_tag="VQ878_001823"
     CDS             8543..9127
                     /locus_tag="VQ878_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3096125.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            9127..9822
                     /locus_tag="VQ878_001824"
     CDS             9127..9822
                     /locus_tag="VQ878_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3096126.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIIMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            9810..11174
                     /locus_tag="VQ878_001825"
     CDS             9810..11174
                     /locus_tag="VQ878_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096127.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         4206 a         1667 c         1976 g         3743 t
ORIGIN      
        1 cgttgacgaa tggttgctgt ttgtgtcgca tcatcataag aaaccacttc agcgacaaac
       61 ttgtactcag ggattttacg gcgagcacca aacaactgct cattttcaga tggtataccg
      121 tagtagaaac ctgttgccaa ttcacgttgg gcaaccttcc acatctcgtc cactaagtct
      181 tgtttgatag cttcaaactt ttcaggactt tcaagatagg catccacagc cgccttgtag
      241 cagttggtta ctgttgatac gtagtgaata gacttcatac gtccttcgat ttttagactg
      301 tccacaccat tttcaatcat atctggaatg tggtcaatca tagacatgtc aacggctgac
      361 attgaaaatt cttctggaat ctcaccctgc aaactcttac gttctttccc aaatggcata
      421 tcgtaaaggt cgtatttcca acggcatgac tgagaacatc caccacggtt ggcatcacgc
      481 atactcatgt ggtttgaaag agtacaacgt ccagagtatg aaatacacat agctccatgg
      541 acaaaggctt caatttcaac atctgtacgt ttgcggatct cagctaattc ttccattgaa
      601 acctcacgcg ctaaaacgac acgagtcaag cctagctctt tccagaactc aagggtttca
      661 tagttagtgg cactggcttg ggtagaaagg tggatttcaa ggcctggtgc ttcagtcgct
      721 gcaatcataa tcaaggctgg gtcagatacg ataactgctg caatcccgat atcacgcagt
      781 ttacggaacc actcaccagc accagcttca tttccttcgt gcataaccat attagccgct
      841 acatagacct tggcaccata cttggccgca aactgcacgc cttcttccat ctgttcgaaa
      901 gtaaagtttc ccgcacggct acgaagacca taggcctgac caccgataaa gacagcatct
      961 gctccatact gaacagctac ctttagcttc tctaaagtcc ctgcaggtga taaaacctca
     1021 ggacgtttta atgtttttgt catgatttct cctatttgca atataaaagt ttgacatttt
     1081 tccttctcat tttatagtaa ataaaggata aaatcaagcc tagacggatt gttttgacaa
     1141 ttctaatctt ttagactttg cataataact gttaaacagt cgaaaattat cccagtttta
     1201 acaagtagtc aaaaagtcta gaaaagtaaa aaccagtatc caaagatact gactcgtaaa
     1261 aatacataaa ttagtcctta gatgactact cccactctgt tgctcctata atggaaaagg
     1321 attgatacag tctagaatat cgctttttta tttattattc tgatataaaa ctgttagaat
     1381 tgattttttg ttttataccc aaatatgaat agagacgtag ctaataagtt gaataacata
     1441 tttggaaaaa tgagaaatag caatattact agaactttta gaaacaatca atatttaaaa
     1501 agaaaaagct caaagaattt attaaaccat gttataatag atatagctat aattttattt
     1561 ataacaagag gatagaaatg accgaattag aaagaaaaaa tcgaaaaatt agctaagaaa
     1621 tattctgata acttaaacat caaagttcaa gagagagttc gtgaaatggc aaatgataat
     1681 aagagccatt atttgatata cagagtttta ggtatttcat ttgaagaagg agaaaatatc
     1741 gatttgtatc aaaataaagg tcgtttttta tacaaatatg ctggttcatt tttagaagaa
     1801 gctgcagtac tatcctttaa cgaaaaattt ggtacagaaa atacttaaaa agttaacatt
     1861 cctaattctg aaagtacaaa acctaagact tttgaaattg attgtttagt cggagaaaaa
     1921 cacgcatacg aaataaaatg gtgggatgca actacagatg gagaccatat aactaaagaa
     1981 cacactagaa taaaagttat tcataacaaa ggatatatac caattcggtt aatgttctac
     2041 tatccaaata gaactcaagc tataaaaatt cagcaaactt tagaaacatt gtataacggt
     2101 attggaggga aatattatgg agattctgcc tgggaagatt taagagcagt gaccggtatt
     2161 gatttactta gtattctaac agatattgca aataaaaaac aggggtaaaa tcaaaatgac
     2221 agtattaaaa ggagataact tagaaatatt aaaaactatt gaatcctcaa gtattgattt
     2281 aatctatatg gaccctcctt tctttacaca gaaaacccaa aaattatcta ataacaaaaa
     2341 tattatgtat tcattcgaag atacgtggac ttcgattgag gattacaaag aatttttgtc
     2401 tgtaagatta gaagaatgca aaagagtgct aaaaaatagt ggcagtattt tcgttcattg
     2461 tgataaaatt gcaaatcatc atattagatt aattttagat aatatctttg gagcagatat
     2521 gtttcaaagc gaaattatat ggaactataa acggtggtct aattcaaaaa agggattatt
     2581 gaacaatcat caaaacattt acttttattc aaagtcaaaa gattttaaat ttaatacaat
     2641 ttttacagag tattcttcta ctacaaatat cgaccaaata ctagtggaac gaaaacgaga
     2701 tggaaactct aaaactatat ataaagttga taataatggt aactatattc tagcaaaaga
     2761 gaaaaatgga gttccccttt cagatgtttg gaatatacca tttcttaatc caaaagctaa
     2821 agaaagagta ggttatccta cacaaaaacc tattctgtta ttagaacaaa ttataaagat
     2881 tgctactgat aaaaatgata tagttttaga cccgttctgt ggaagtggaa ctactttagt
     2941 agcctccaag attttgaata gaaattatat ggggattgat ttatctgagg aagctatcaa
     3001 tataactcag caacgtctgg aaaatgttat aaaaacaagt tcagatttat tgaataaagg
     3061 aatcgaagca tatagaacca aaactgagga agaggaaaac attcttaaat tattacaggc
     3121 aaaaattgtt caaagaaata aaggaattga tggtttttta cctaaacatt ttcaaaaaaa
     3181 accgatacct ataaaaattc aaaaaaataa tgaatgtctg aatgagagta tctctttatt
     3241 acagaatgct ataaactcca aaaaacttga ttttggagta gttataaaaa ctcattcaga
     3301 taatttatta tttgattttg atacgattcc tgaaaatata atagtagttg accattttga
     3361 acttacaatc gaaaaatggt taagtaaaag tcaacagtta ctatagtttg caaattattt
     3421 acagaaagaa caaaaaatgc tctgaaacac tgatttcaag gcattttttg ttagtttaaa
     3481 attactccca ttcttctttt ccaaacatac aatatatcca aaaccattca aaatactaga
     3541 ttctattttt tataatatca ctaaatccac ctaattatag gacgttttca gatttttagt
     3601 cccgtcccag tcccagtacc ggagaaatat tgttttaata taatatctct ttttgtcttc
     3661 taagctctta aaagcaaaag aacaagtaaa gagtcaagac aaggataaaa agtccatatt
     3721 agggcaaata aaaagcttta agacagatga caaatctaag tcaaataaga aagaccatag
     3781 caaaggtgca gagagataaa tattggcggt cttcggactg cctttatttt tttatccatt
     3841 tttcaaatca aatttattca gactatatat gcacatatac acttaaattc atataaaaac
     3901 atggcttgta aaaaattact ttaatcacaa taatcgcatt taaaattgtg atgtttgcaa
     3961 gctaaattac ggacttcact tggaagtttt cccttgtatc ttttataata gatagaaaat
     4021 ttgctggcag atgaatatcc aacagattct gctatctctt ttataggtag ttcagtgttt
     4081 aaaagaagag tttcagctac attcattctt tttctttgag tgtactctgt aatgctttga
     4141 caatattttt ccttaaataa attttttaat ttagtaccac tcattttaga tattttttca
     4201 agcgtgcctt gatttacatt cgttgcaaaa tgatcatcta agaatcttgc tacatcttca
     4261 agtgctttat catcatcaat ttcaatttta tatttttttc tatttaagta tgtgtcaatt
     4321 actatactta tccattcatt tgcctttgct ttaaagaaaa aatcagcggc aggagcgtcc
     4381 atcttacaat ttaatatttc cattgccact ctttctaagg cctttgtaag tattatttga
     4441 ttcgattgaa gcaaggttga ataaaaagat tctggattaa tgttaataga tgctaaatgt
     4501 ttttctatta gctctttttt aaaaccaatg gaaacagcaa gataacaaca attctcgtgt
     4561 aataaaaaaa caaaatcatc ttttatatta tcaaaatcaa aagtacataa agagtttgcg
     4621 gtaatagttt gatacggatt aaacttttct ccgtttgcac tgacaatgta acttgaataa
     4681 attgaaacat agtctgacat actataagtg ctattttgaa ctacttcctc tttgatataa
     4741 aaatcatgta tatcgataat gaagctgcct ccttcataaa accaatatag gccttctgca
     4801 taagttgaat tctctttttt ccaacaaaat gtatgacctg cacttgaata cttctcattg
     4861 tttttacatt catctacttt catataatct tttacaaaat cataatatga cataacacac
     4921 tatccctttt agacaatatt ccaattagcc ttattaattc aaaactattg tattagtaat
     4981 tataacagat gtataataga aaagcaatga tagatattat caattaagcg aatttatatc
     5041 taaaagggat attaaagaaa ggagatatgc ttatgaagat ttacaaaaaa ctatttgctt
     5101 atgtccaaga taagaaatat cttggggttt tggccataat tttttttgct atatctgctg
     5161 cacttacagt atatggatat tatttaatct acaaatttct agataagtta ataattaatt
     5221 caaacttatc cggtgcagag agtatagcat taaaatctgt tattacacta acaagtggag
     5281 cgatatttta ttttgtctca ggaatgtttt cacatatctt gggatttagg cttgaaacaa
     5341 atttaagaaa aaggggaatc gatggtctgg aaaaagcaag ttttaggttc tttgacttaa
     5401 atccatctgg tcaaataaga aagatcatag atgataatgc agcacaaact catcaggtgg
     5461 tagcacacat gattcccgat agttctcagg caataatcac acccgtactt gtacttgcac
     5521 ttggctttat agtaagtata agggttggca taattttgct tgctcttact ataattggtg
     5581 gcttaatttt aggggcaatg atgggcgagc aagaatttat gaagatatac caagaatccc
     5641 tatctaaact aagtgctgaa actgttgagt acgtgagagg aatgcaagtt gtaaaaatat
     5701 ttaaagcaaa tgtagagtct tttaaaagct tttataaggc gataaaagat tactcaaagt
     5761 atgcttatga ttattcccta tcttgtaaaa ggccttatgt tttgtatcaa tggttatttt
     5821 ttggactgat tgcaatttta attattccta tagtttattt tatgactagc ttagctagcg
     5881 caaaggtgat tttacttgag cttatcatga ttttattttt atcaggagtt ctctttgttt
     5941 cattcatgag aatgatgtgg tactccatgt atatttctca aggaaattat gcagtagata
     6001 ctttagaggc gctttacgaa gatatgcaaa aagacaaatt agtgcatggt aatgtcaata
     6061 attttaaaaa ctataatata gaatttgaga atgttagctt tgcttataat gataaagctg
     6121 tcattgaaaa tttatccttt aatttagaag aaggaaagtc ctacgcactt gtcggttcat
     6181 ctggatcagg caaatcaaca gtagcaaaac ttatatcagg tttttacaat gttaataaag
     6241 gaagcataaa gataggcggg atagcaataa gtgaatattc tgacgaagcc ttaattaaag
     6301 ccatttcctt tgtttttcaa gattcaaaat tattcaagaa gagcatttat gataatgtag
     6361 ctttagctaa taaagatgcg acgaaagatg acgttatgag agccttaaaa ttagcaggat
     6421 gcgatttaat attagacaaa ttcccagaaa gagaaaatac aatcataggc tcaaaaggtg
     6481 tttatttatc cggtggagaa aaacaaagaa ttgcaattgc tagagcaatt ttaaaggatt
     6541 ccaaaattat tattatggat gaagcatcag catctattga cccagataac gagtttgaat
     6601 tgcaaaaagc ttttaaaaat cttatgaagg ataaaacagt tatcatgatt gcacacaggc
     6661 tatctacaat taaagacctt gatgaaatta ttgtcatgga tagtggaaaa attatagaaa
     6721 gagggtctga caaagaatta atgtcaaaag atacaaggta taagagcctg caagagatgt
     6781 ttaacagtgc gaatgaatgg agggtttcaa atgaaagagt tttataaaaa aagatttgct
     6841 cttacagatg gaggagcaag aaatttaagt aaagcaacac tggcttcatt tttcgtttat
     6901 tgtataaaca tgcttcctgc catattactt atgatttttg ctcaggaagt tttggaaaat
     6961 atgggcaaaa gcaatggctt ttatatagta ttctcagttt tgactttgat agcaatgtat
     7021 attttgcttt ctatcgaata cgataaatta tataacacaa cctatcaaga aagtgcagat
     7081 ttaagaataa ggacagcgga gaatttatca aaattacctc tatcttactt ttctaaacat
     7141 gacatttccg acatttcaca aacaatcatg gctgatattg aaggcataga gcatgcaatg
     7201 agccactcaa taccaaaggt gggcggcatg gtactgtttt tcccattaat atctgtaatg
     7261 atgctagcgg gcaatgtcaa gatgggttta gctgtaatta ttccatctat tttaagcttt
     7321 atatttatac ctttatctaa aaaatatcag gttaatggac agaatagata ttatgatgtc
     7381 ttaagaaaaa actcagaaag ctttcaagaa aatatcgaaa tgcaaatgga gattaaagca
     7441 tataatttat cgaaggatat taaagatgac ttatataaaa aaatggaaga tagtgagaga
     7501 gtacacttaa aggcggaagt aactacaatt ttaactttgt ctatatcttc aatatttagc
     7561 tttatatctc ttgctgttgt gatatttgtc ggcgtaaatc taattattaa taaagagata
     7621 aattctctct accttatagg atatttacta gctgctatga agataaaaga ctctttagat
     7681 gcatctaaag agggcttgat ggaaatattt tatttatcgc ccaaaataga aagattaaaa
     7741 gaaattcaaa atcaagatct acaagaaggc gatgactata gcttaaaaaa atttgatatt
     7801 gatctaaaag atgttgagtt tgcctacaat aaagacgcaa aagttttaaa tggtgtaagt
     7861 tttaaagcta agcagggaga ggtcactgct ttggtaggtg caagtggctg cggtaaaaca
     7921 actatcttga aacttatatc aagactttat gattatgaca agggacaaat cttaatcaat
     7981 ggcaaagata taaaagaaat atcaacagaa tctctttttg ataaggtctc tatagttttc
     8041 caagatgtgg ttctctttaa tcaaagcgtt atggaaaata ttagaatcgg aaagcaagat
     8101 gcaagtgacg aagaggttaa aagagcagca aaacttgcaa attgcacaga ttttatagaa
     8161 aaaatggata aaggtttcga tacagttatt ggtgagaacg gagctgagct atcaggagga
     8221 gaaagacaaa gattatcaat agccagagcc ttcttaaaag atgcgccgat attgatctta
     8281 gatgagataa cagcaagcct tgatgttaac aacgagaaaa agattcaaga gtctttaaat
     8341 aatttagtta aagataaaac tgttgtaatc atttcacata gaatgaaatc catagaaaat
     8401 gcagacaaga tagtagttct tcaaaacgga agagtagaaa gcgaaggtaa gcatgaagag
     8461 cttttacaaa aatcaaaaat ttacaaaaat ttaatagaaa agacaaaaat ggcagaagaa
     8521 tttatttatt aggaggacta caatggataa taaaaaatta aaagtaaaag atttagtaag
     8581 catcggtgtt tttggcgtaa tttattttgc cttcatgttt ggagttggta tgatgggctt
     8641 gattccaata ttgttcttaa tatacccgac agtattagcc atagttgcag gaactgttgt
     8701 tatgttattt atggctaagg ttcaaaagcc atgggcacta tttatatttg gtatgatatc
     8761 accacttgtg atgtttgcag ctggtcatac ctacgtagtt gtggttttat cacttatagt
     8821 aatgataata gcagaattaa ttagaaagat tggtaattat aattcattta aatacaatat
     8881 gctttcttat gcaatcttca gcacatggat atgtagctct ttaatgcaaa tgcttttagc
     8941 aaaagaaaaa tatatggagt ggtctttgat gacgatggga aaagattatg ttgatgtatt
     9001 agaaaagtta ataacttatc ctcacatggc tttagtagcc ttaggtgctt tcttaggagg
     9061 aattcttgga gcatatatag gcaaggctct attgaaaaaa cactttgaaa aagcaggcat
     9121 tgtataatgc ctactttttc ttcaaatgct ccctttaatc ccaatccgat ctctaagata
     9181 ttagtcgtat ttatcacagg cttaactgtt atgcatagca taaacatccg ttttgagctg
     9241 gcaattgttt gtcttattgg tattttgctt tatttgaatg gatacaaaaa aacacttttc
     9301 aaatggatta tattgtgtgg gatactttac tccttgccta attttatggt gttatctgaa
     9361 ttaaacccta tagttaagat gtttttgagt atacctattg ttattataat gtttatttta
     9421 ccatttatgg cagcaagctt tatgataaag acctcggatg taggcgcaat aatttcatcg
     9481 atggataagc ttaagatttc aaagaatgta tccataccta ttgcggttat gtttagattc
     9541 ttcccatctt ttaaggagga gaagaaaaac atcaaaatgg ctatgagagt aagagggata
     9601 aattttaaaa acccagtcaa atatcttgaa tatgtttctg tgccactact cattatatca
     9661 tctaatatat cagatgacat tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt
     9721 gccaagacca gatacattcg cgtaaagata cagctaattg attttgttta tgttttagcg
     9781 gttgttggac ttattgtggg aggcttaata tggttgaaat aaaaaattta agtcttgatt
     9841 atggtgaaga gcatatatta gatgatatat cactatccat agccgaggga gagtgcgtgc
     9901 tatttacagg aaaaagtgga aatggtaagt catctttaat aaattcaatc aatggactag
     9961 ctgtaaggta tgacaacgca aagacaaagg gcgaaatcat tattgatggt aagaatataa
    10021 aaaatttgga actttatcaa atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga
    10081 catatttttt taatgtcaat acgacattag aattattatt ttatttggaa aatatcggtc
    10141 ttgcaagaga agagatggac aggcgtttga aggatatgct taagatattc ccgataaaaa
    10201 atcttttgaa cagaaatata tttaatctat ccggcggtga aaaacaaatt ctttgcattg
    10261 cagcttctta tatagcaggt acaaagatta tagttatgga tgagccttca tcgaatttag
    10321 atattaaaag cataagtgtt ttggcaaaga tgctaaagat attaaaagag aaaggtataa
    10381 gcataattgt tgcagagcat agaatttatt atttgatgga catagttgac cgtgtatttt
    10441 taatagataa aggaaagctt aaaaaaactt atactagaag tgaattttta aagctagata
    10501 aaaatgaatt aaatgcttta agtttaagag ataaagaatt aagtaaatta aaagttcctt
    10561 atttaaaaga aggtggagag tatcagataa aaaatcttag ctacaaattt actgatgatg
    10621 agtgtttaag cttaaaagat atttcattca agcttgggaa aatttatggc ataataggat
    10681 ccaacggacg aggaaaatca acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa
    10741 aagaagaaat ttattttaag ggagagaagc tatctaaaaa agaaagactc aaaaactctt
    10801 cacttgttat gcaagatgta aatcatcaat tattcacaga tgaagtattc aacgagctta
    10861 gattaggagt aaagaatttt gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc
    10921 tggacgaatt tattgaaagg catccgatga gtttatcagg agggcaaaag caaaggcttg
    10981 caatagcatc tgttatgtgc aagacttctc catttgtctt ttttgacgaa ccttcaagtg
    11041 gtatggatta ttccaatatg ataaaaatat ctgaactgat taataagtat aaaaccatgg
    11101 ataaaataat ttttattgtt tcccatgata tagaattttt aaatgaagtg gcagatgaaa
    11161 tttttgaatt gtaaaataga gtctgttaaa catgtctata gaactagtaa attgtctaaa
    11221 aatttaaaag atactaacac atattgatat ttattagaaa attaacttca ggatttttac
    11281 agtatttata aactttataa tatgtattta tagtattaat aatttccata tctttaggga
    11341 aattctttat ttacttacca taattaaaga gatgagagat aaatatcggc agtcttcgga
    11401 ctgcctttat ttttttactt aatttaatgc agtaaatcat acgattgaaa ggaatctgcg
    11461 ttatatgcta taattaggtg gttaatctat acatttagaa aggtaaaata tagaattgga
    11521 gaatgatatg ggattttcat ataataaatt gtaaccgtcc aataacgaag tatattgaaa
    11581 aatctccaga ct
//
LOCUS       DAVBOM010000061        11444 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBOM010000061 DAVBOM010000000
VERSION     DAVBOM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.061"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(113..2110)
                     /gene="metG"
                     /locus_tag="VQ878_001826"
     CDS             complement(113..2110)
                     /gene="metG"
                     /locus_tag="VQ878_001826"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET3096128.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEITYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2234..3493)
                     /locus_tag="VQ878_001827"
     CDS             complement(2234..3493)
                     /locus_tag="VQ878_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3096129.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3495..4196)
                     /locus_tag="VQ878_001828"
     CDS             complement(3495..4196)
                     /locus_tag="VQ878_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096130.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4180..5379)
                     /locus_tag="VQ878_001829"
     CDS             complement(4180..5379)
                     /locus_tag="VQ878_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET3096131.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5644..6990
                     /gene="gor"
                     /locus_tag="VQ878_001830"
     CDS             5644..6990
                     /gene="gor"
                     /locus_tag="VQ878_001830"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET3096132.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDSSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMRATKADFDATVAIHPTSSEEFVTMR"
     gene            7186..7722
                     /locus_tag="VQ878_001831"
     CDS             7186..7722
                     /locus_tag="VQ878_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET3096133.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7773..7859
                     /locus_tag="VQ878_001832"
                     /pseudo
     CDS             7773..7859
                     /locus_tag="VQ878_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7928..8143)
                     /locus_tag="VQ878_001833"
     CDS             complement(7928..8143)
                     /locus_tag="VQ878_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET3096134.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8241..8561
                     /locus_tag="VQ878_001834"
     CDS             8241..8561
                     /locus_tag="VQ878_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096135.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8592..8930)
                     /locus_tag="VQ878_001835"
     CDS             complement(8592..8930)
                     /locus_tag="VQ878_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096136.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8942..9661)
                     /gene="trmD"
                     /locus_tag="VQ878_001836"
     CDS             complement(8942..9661)
                     /gene="trmD"
                     /locus_tag="VQ878_001836"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET3096137.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9651..10169)
                     /gene="rimM"
                     /locus_tag="VQ878_001837"
     CDS             complement(9651..10169)
                     /gene="rimM"
                     /locus_tag="VQ878_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET3096138.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10200..10988)
                     /locus_tag="VQ878_001838"
     CDS             complement(10200..10988)
                     /locus_tag="VQ878_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3096139.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11092..11335)
                     /locus_tag="VQ878_001839"
                     /pseudo
     CDS             complement(11092..11335)
                     /locus_tag="VQ878_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3289 a         2515 c         2081 g         3559 t
ORIGIN      
        1 aacctcaaag cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt
       61 cattgagtat aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa
      121 tcacacttcc atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt
      181 cagctgatag aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt
      241 tagcaacgat ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa
      301 ttcctgaaag aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact
      361 tatctgaacc ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt
      421 caaagtcttc aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc
      481 attctttttc gactgctggt ttattgcctt ccatttgttc cttgatatag gtgatttctt
      541 cttccatatt tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg
      601 ggaagtcagc caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca
      661 aaactgcacg actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc
      721 tggctgccaa gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca
      781 agacccatgg tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg
      841 cttcaagcgc acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt
      901 gttctgcaac ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga
      961 tttgtccatc aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt
     1021 cattagccaa ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg
     1081 aaccaactgg aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta
     1141 ccaacatttc agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga
     1201 caaaccaacc atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga
     1261 ttggccagta gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc
     1321 cattccagaa cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat
     1381 agttaagaag ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca
     1441 ctccccatgt aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt
     1501 tgcgtagcat ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa
     1561 attcgaccaa acggtcttgg tatttgctaa ggcgaagaaa gtatgattct tcagaaaccc
     1621 attcaacctc atggcctgat ggagcaatac caccagtcac atttccagct tcatcacgga
     1681 aaacttctgc cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag
     1741 agtattcacc caagtagata tcatcttgag caagtaagcg ttcaaagact tgtgcgacaa
     1801 ctttttcatg gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt
     1861 gccagagttc tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag
     1921 cttcttccgc tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata
     1981 catcgtagcc catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg
     2041 cagaaccgat atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt
     2101 tttcagacat aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat
     2161 atcacatttt taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc
     2221 catcttgttg atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt
     2281 tggctggcaa gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg
     2341 caactgggat tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg
     2401 ctaaggcagt taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa
     2461 tcatggattc aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc aaagccttac
     2521 gaagaccaat ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag
     2581 ttcctccaac aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa
     2641 acgattgttg aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt
     2701 gtaagcctgc aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac
     2761 tggtatcatt cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa
     2821 gggagatatt ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct
     2881 ccggactagt ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt
     2941 taatagcctc ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa
     3001 cacttgcaaa ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct
     3061 taacagcgtc catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat
     3121 cttgataggt caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca
     3181 gtttagctgc ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct
     3241 cttcctttcc agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt
     3301 ttttaggaga gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt
     3361 gacgagatag ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa
     3421 tcccaatcat agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt
     3481 tcagattctg catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc
     3541 ccatcccgaa tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc
     3601 atgataatgg tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct
     3661 gttttggtat ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc
     3721 aaggcacgcg caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg
     3781 tgactacgtt ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt
     3841 gaagacgaaa ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc
     3901 gatagaagaa agaactgctg aaagacaaaa ccgatttgtt ggttacgaac cttagctagt
     3961 tgtttttcac caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt
     4021 gtatccaaca tgccaatcgt attcatcaga gtggacttac cagaaccaga tggccccatg
     4081 atggctacaa attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct
     4141 tggtcaccat tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc
     4201 cttcacctct tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt
     4261 tgtcaaacca gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac
     4321 ttttttagcc ttttgttgtt catccacaat ccagacataa tttttactat catccattac
     4381 tagactgcta acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga
     4441 aaaaccttgt ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga
     4501 acctgtatta ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga
     4561 aatatagctt aatttcccag tccatttttt atcaggatac actttagaag taaagcttac
     4621 ttcttgacct acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa
     4681 attttcattg ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac
     4741 attgctattg acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa
     4801 ttgactttga gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc
     4861 caattgagca tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt
     4921 tgcatcttct cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt
     4981 tcgtgcttga ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga
     5041 atcataggcc gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac
     5101 cttatcgccc acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac
     5161 atattgttca ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc
     5221 ttccttggca acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct
     5281 aaaaagtaaa atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata
     5341 cagttgccac tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt
     5401 tacaatactt tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaag
     5461 caatcgttcg gaatttttct tttctattgt actagatata taatacacta tcttgactta
     5521 tttggcaagc ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa
     5581 agaataaaat ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt
     5641 tcaatgagag aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg
     5701 aaccgtgctg gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga
     5761 acctgtgtca acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc gcaaatcgct
     5821 gagactttcc atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac
     5881 tttgcaaccc tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc ttcttatgat
     5941 agtagtttta aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct
     6001 catactgtaa gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt
     6061 gcccatccaa gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta
     6121 tttgcctggg aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt
     6181 gaattagctg gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat
     6241 cgtcctttac gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga
     6301 ataaacttgc cacttcatac tcacaaagtc cctgccaagt tagaaaaaac tgctaaaggc
     6361 attaccattc atttcgagga tggtaccagt cacacagcta gccaagttat ctgggctaca
     6421 ggtcgccgtc caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac tctgaatgaa
     6481 cgtggcttta tccaagtaga tgaataccaa aatactgttg ttgagggaat ctatgctcta
     6541 ggtgatgtaa caggtgaaaa agaactgact ccagttgcaa tcaaggctgg gcgtacccta
     6601 tcagaacgtc tctttaacgg aaaaacaact gcaaaaatgg attactcaac tattccaact
     6661 gttgtctttt cacaccctgc tatcggaact gttggtttga cagaagaaca agctattaaa
     6721 gaatacggtc aagaccaaat caaggtttac aaatcaagct ttacttctat gtactctgct
     6781 tgcacttgca accgtcaaga aactcgtttc aaattgatca cagctggttc agaagaaaaa
     6841 gttgtcggac ttcacggaat tggctacggc gttgatgaaa tgattcaagg atttgctgtt
     6901 gctatcaaaa tgagagcaac caaggctgac tttgacgcaa ctgtagcgat tcacccaact
     6961 tcatctgaag aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt
     7021 ctgcttcttt tttaatgatt ttcgaatcaa caaaaaatta tccaacttga ctagtcacga
     7081 aaatcggctg ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta
     7141 tatgagtata atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac
     7201 gtttatgcta tccctgctat tggggctgct ctcattgctg ttttggcaca aatcagtctt
     7261 ccaattggac ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc
     7321 tttagaccga gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt
     7381 cttcctgtct ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc
     7441 tatctttggt tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt
     7501 ggtgttgtta agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg
     7561 attctcagct tgcatttcct agctggaatg gcatttgaaa aagctcttgc tgtgggggtt
     7621 cttcccttta tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc
     7681 ctacttcaac gccttaaaaa tcaggcttac tttactaact aaaaaaggat atcgagttat
     7741 catgactcaa tatccttttc ttttattttg aaaacttata ctcaatgaaa atcaaagagc
     7801 aaactagaaa gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg
     7861 acgaagtcag taaccataca tacggcaagg caaagctgac gcggtttgaa gagattttcg
     7921 aagagtatta gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag
     7981 taatcccttt gcccatttta gtatggtctg gactccaagc acgaatatca aactttgcag
     8041 gggcaccatt aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa
     8101 gagtcaacaa gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta
     8161 gtttcattag tttattcgta aaatcttgta gattttagga aaattttata taatattgat
     8221 ataaaagaag ggaggccaat atgagacata aattccagca agttctaaat aaaatacatg
     8281 attttttaaa tggatatgac caacctgacc agactgaaac caactccctt acagccacta
     8341 ttgaagaggc tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta
     8401 caggtgatat catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca
     8461 aaaatgtgag ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa
     8521 ctgtccaaac agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc
     8581 actctttttt cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa
     8641 ccacttcttt ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatggtaatg
     8701 taacctgcgc ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt
     8761 tccaccttgg cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga
     8821 cgcaaatcat ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc
     8881 ttatctggat taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc
     8941 tttattcttt gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat
     9001 aatgttcaag taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc
     9061 actgacgaat cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat
     9121 aatcataggg acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt
     9181 ggtggctaga ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg
     9241 tcatagctgc caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta
     9301 ccaaggtctt aatgcgctca tcataaccct catagtgccc acagataaag attagctctt
     9361 cctcttgagc caaatcttca gcataaacct gatcaaactg ctttccagca ggatcgagga
     9421 gaataacgcg cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc
     9481 tgagcaacat gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag
     9541 cattttctcg aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa
     9601 cgattgagtg ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca
     9661 tcgtctaacc cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga
     9721 accactggtg ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag
     9781 acatcattag cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca
     9841 tagacttcca aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa
     9901 tcttcctcag cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac
     9961 atatctttga atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact
    10021 gtttggacaa actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt
    10081 tcttctgcaa aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta
    10141 acgattttcc caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct
    10201 tattctgaca attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa
    10261 tggtgattcc ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac
    10321 tctttttctc tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa
    10381 ttctcaaaat cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc
    10441 aactctaagc ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat
    10501 gttgcttgag ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc
    10561 tgctcttcca tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt
    10621 gtcggttcaa ttgctactaa agtctgacgc ttaattggtt tctcgagtaa tttgcaagct
    10681 aaaattccac tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt
    10741 acttcataaa ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga
    10801 ctcctacctg tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca
    10861 agtataagtg aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc
    10921 actttctttt gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac
    10981 ctcttcataa agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta
    11041 ttttatcacg ttccaaagat tttctcaagt tggaggaagg ggacaacatc tctactttcc
    11101 cttcaagaat ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt
    11161 ctcaaagatg gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg
    11221 aatgatatca gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac
    11281 cagagcgcct attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga
    11341 gaccttcatc agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa
    11401 acgttcaatc ttttatagta tattgaaact agaatagtac acct
//
LOCUS       DAVBOM010000062        11266 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBOM010000062 DAVBOM010000000
VERSION     DAVBOM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.062"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(392..1528)
                     /gene="dnaJ"
                     /locus_tag="VQ878_001840"
     CDS             complement(392..1528)
                     /gene="dnaJ"
                     /locus_tag="VQ878_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET3096140.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1733..2086)
                     /locus_tag="VQ878_001841"
     CDS             complement(1733..2086)
                     /locus_tag="VQ878_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096141.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(2099..3922)
                     /gene="dnaK"
                     /locus_tag="VQ878_001842"
     CDS             complement(2099..3922)
                     /gene="dnaK"
                     /locus_tag="VQ878_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET3096142.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4402..4926)
                     /gene="grpE"
                     /locus_tag="VQ878_001843"
     CDS             complement(4402..4926)
                     /gene="grpE"
                     /locus_tag="VQ878_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET3096143.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4953..5987)
                     /gene="hrcA"
                     /locus_tag="VQ878_001844"
     CDS             complement(4953..5987)
                     /gene="hrcA"
                     /locus_tag="VQ878_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET3096144.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6151..6660)
                     /locus_tag="VQ878_001845"
     CDS             complement(6151..6660)
                     /locus_tag="VQ878_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET3096145.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7268..7568
                     /locus_tag="VQ878_001846"
                     /pseudo
     CDS             7268..7568
                     /locus_tag="VQ878_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            7763..9601
                     /locus_tag="VQ878_001847"
     CDS             7763..9601
                     /locus_tag="VQ878_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3096146.1"
                     /translation="MKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQII
                     HRLRKAGLAKRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYL
                     GLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGM
                     TATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKV
                     DTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHA
                     ERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTT
                     GVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDF
                     DGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLIT
                     ESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQE
                     IDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGEL
                     ESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9614..11077
                     /locus_tag="VQ878_001848"
     CDS             9614..11077
                     /locus_tag="VQ878_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3096147.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            11077..>11266
                     /locus_tag="VQ878_001849"
     CDS             11077..>11266
                     /locus_tag="VQ878_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HET3096148.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3435 a         2207 c         2212 g         3412 t
ORIGIN      
        1 ccatggcaag ccgacgctga cgtggtttga agaaattttt gaagagtatc attcaccatt
       61 tcacaactaa atcgaagact ttctgccgta atgaaaacac ctgaaacagc ttggtttcag
      121 ctgtccggaa actttaagac ttaggttcaa agtttaggta tggaacttcg aaggaggtcg
      181 ctaccgtccg tcattactta ggaaagtctt aaaaaatcta taaagtaaaa agagcccgac
      241 agctcttttt gtttatactc aatgaaaatc aaaaagcaaa ctaggaaact agccacgggc
      301 tgctcaaaac actgttttga ggttgtagat acgactcaca tatatacggc aaggcaacgc
      361 tgacgtggtt tgaagagatt ttcgaagagt attattctcc atcaaaggca tcttttatat
      421 ggtcaaagaa gccttttttc tttggattta ctttcaagtc accagcagtc gcgaattctt
      481 tcaaggctac tttttggcgg tcgttcaagc ctgtcggtgt tacgacatta acagtaacgt
      541 attggtcacc aactgcaccg ccacgaaggc tcggtgcccc cttactacgt aggcggaatt
      601 tcttaccagt ctgagttccc tctggaataa ccaattcaac atcaccgtga acagttggaa
      661 tatctactgt atcaccaaga gccgcttgga caaagttgag gttgagattg tagaagatag
      721 tcgttccttc acgttcaaac ttgtcgctag cttctacaga aactactaca tacaagtcac
      781 cataaggtcc accgttaaag cctgcttcac cttgaccagc gaggcgaatt tgttgacctg
      841 tttccacacc agcagggatt ttcacatgta cgctatgagc ttgtttctca tgacctgttc
      901 catgacaggt tgtacatgga tatttgattt cttttcctcg accgtgacag acatcacagg
      961 ttacttggcg acgcatcata ccaagaggag tctgcgtatc gacgttaatg acaccagcgc
     1021 catgacagcg tccacaagtg actggacttg tccctggctt agcaccagag ccattacatg
     1081 tacgacagcc agcttcacga tgatacttaa cttccttctc agttccgaag atagcttctt
     1141 caaatgtcaa attgacacga tactggagat catctccttg gcgaggagcg tttggattgc
     1201 gcgaagaacc gcctccgccg aagaaacttg agaaaatatc ctcaaaacca ccgaagccac
     1261 ctgccccatt gaaaccaccg aaaccaccag ctccaccaaa accaccattg gcgcctgcag
     1321 caccatactg gtcataggca gcacgttttt ggtcgtcact caaagtctca taggcttctt
     1381 gaacttcctt gtacttgtcc tcagcaccag gctccttgtt gatatctggg tgatattttt
     1441 tggaaagctt acgataagcc tttttgatct cgtctgccga agcgtttttt gacaccccca
     1501 gacgatcata aaattcagta ttgttcatac aagataccaa gaccgtaaaa ttcgactgaa
     1561 aaataggaaa tctgacgctg gagcgacgct cctagacaga tttctctttt ttccgagaat
     1621 ttaggtcggg ttcaattcct ttcttttata ttgatgagat aatactccag ccactcggcc
     1681 ctatcccttt ttaccgaaaa acagaggctg ggttgcaacc tctgtggtta gattattcat
     1741 ttgaaataaa aatggttgta ttatctctag tagtaatctt caaagacctt ttagctaaat
     1801 caaactcaaa tttattatag tgtgggtctt gtgttttata taggtgtaac tcctgacata
     1861 tatgatccga aaagtaaatc ataacatctt taaacacaga agtgtagtca tatttactct
     1921 taccaacagc tacttctgta aattctttat aaatgacatt tccatttctt tccacagtca
     1981 ccagcatttc tgttggatta taatccaaat taaataattc ttcaaaaaac tttatctttt
     2041 catgataatc tgcaatgtca gaaagattat ttttattaac actcataaca ctagcccctt
     2101 atttttccgt aaactctccg tctacgacgt catcgcctgc gtttcctgtt gcttgtgcgc
     2161 cttctgctcc ttcttgagct tgttgcgctg ctgcggcttg ttcgtagagt ttaacagcaa
     2221 gtccttgagc tttttcgttc aatgcttcaa gtttcgcttt catgtcgtcc aagttgttgt
     2281 cttcttgagc tttcttaagg tcatcaaggg cagcttgggc agcgtcacgt tctgcgtcga
     2341 agcctttacc ttcagtttcc ttgattgtct tttcagtcgc aaagattgct tggtctactt
     2401 cattacgaag gtctacttct tctttacgtt tcttatcggc ttcagcgttt gcttctgcat
     2461 ctttcatcat gcggtcgatt tcttcgtcag tcaaacctga gttcgattgg atgacaatag
     2521 tttgttcttt ttgagttcca aggtctttgg ccttaacaga cacgataccg ttcttgtcga
     2581 tgtcaaatgt tacttcgatt tgaggaattc cacgaggtgc agctgggata tcagtcaatt
     2641 ggaagcgtcc aagagtcttg ttatctgctg ccattgggcg ttcaccttga agaacgtgga
     2701 tatcaacggc tggttggttg tctgctgctg ttgagaagac ttgtgattta gatgttggga
     2761 ttgtagtgtt gcgatcgata agttttgtaa atactccacc cattgtttcg ataccaagtg
     2821 acaatggcgt tacatcaaga aggacaacgt ccttgacatc accagtaatc acaccacctt
     2881 ggatagccgc acccatagca actacttcat cagggtttac tgatttgttt ggttctttac
     2941 cagtttcagc tttaacagct tcaacaacgg cagggatacg agttgaacca ccaacaagga
     3001 taacttcgtc gatttctgac aagctcaaac ctgcatctga aagggcttga cgaactggaa
     3061 cttttgtacg ttcaacaagg tcacgagtca aatcatcaaa tttcgcacga gtcaaagtca
     3121 tttccaagtg aagaggtcca gcctcacctg cagtgataaa tggcaagctg atttgtgttg
     3181 aagttacacc agaaaggtct ttcttcgctt tttcagccgc atctttcaaa cgttgcattg
     3241 ccatcttgtc agtagacaag tcgataccgt tttctttctt gaattctgct accaagtggt
     3301 caatgatttt ttggtcaaag tcgtcaccac caagtttgtt gtcccctgca gttgacaata
     3361 cgtcgaagac accgtcaccc aattcaagga tagagacgtc gaatgtacca ccaccaaggt
     3421 caaataccaa gattttttct tctttatcag tcttgtccaa accataagca agagctgctg
     3481 cagttggttc gttaacaata cgttctactt caagaccagc aattttacca gcgtcttttg
     3541 ttgcttgacg ttgagcgtcg ttgaagtaag ccggaactgt gataacagct ttggttactt
     3601 tctcaccaag gtagtcttca gcgtagcctt tcaagtattg aaggatcata gctgagattt
     3661 cttgtggagt gtattctttt ccatttgcag aaactttttc agaagttccc atcttagatt
     3721 tgatagagat aactgtatct gggtttgtga ctgcttgacg ttttgcagca tcaccaacga
     3781 tgatttctcc gtttttgaat gagactacag atggagttgt gcggtttcct tctgggtttg
     3841 cgatgatttt gctttcagtt ccttcaagaa ctgcaactgc tgagtttgtt gtacctaagt
     3901 caataccgat aattttagac atgtgttttt ctccttgtta gttaattttc tatttttctt
     3961 tttgatactc ttcttaagtg gcgacgccgt cagagcttga cttcgtcaat ctctttgact
     4021 aaactttgag cctaaggtct caaaatttgc gcaaatagcg ccacggcgaa gagtatcgtg
     4081 tttggttcgc ttcgctcact attacaaagc caaacatatt ttatctttct tcatagttta
     4141 ttgtcgtttc ggacaagttt tctattatgt aaattgcgac acgaagagtc gaaatcgatt
     4201 ttatttcgac gacgagttag taaggaagct aggcaaacgc catagcgatt gccgttttct
     4261 gacgagttgc tttagctacc gtcagaattg ccgaatcgaa cacgccctaa gctctgagta
     4321 aaaaagatag attttcttgt gttcatcgaa cacttcgtta atctcctatt tttactgcga
     4381 gctttttacg ggctttgtat cttagttata caccactacc attgctgggc gtaggatgcg
     4441 gtcatggagt ttgtagcctt tttgaaagac ttgagcgatg gtatctactg ggtgttcatc
     4501 gtctgctggg agagtttgga tggccatatg gtagttatgg tcaaattcgc catctgctgc
     4561 gatttcttca attccttctt ctttcaaagc gtgaatcaag ctttcttgca ccatccccaa
     4621 gcccttcttc acatcatctg tcaaaccttc aactgcaagt gcacgctcaa ggttgtcaag
     4681 agatggtaag attgcttttg ccaagtcctg gctacgataa cgttgcaagt tttgacgttc
     4741 ttcattggca cggcgttgga tattttgcat ttctgcatga gcgcgaagat atttgttttc
     4801 gaactcatct gcacgttcat ttgccaagtc caactcagac ttttcaggag ttgtttcttc
     4861 agctgtttcc acaacttcct cttcttgaac ttcttctact tcttcatttt ttatatcttg
     4921 ggccatgttc gcctccttta atgatttcaa tcttaatgta cttcgtaatg attactgctg
     4981 aggtagcggt aaaaatctgt caacttcatg gtcaaaacac ggttgaccac attgatttga
     5041 ttgattagct gttggtaatc cagattaact ggaccgataa tggctagaat tccaactccc
     5101 cgataaggaa tgaggaactt actactaatc accgctaggt cagctaaaca ggactcttga
     5161 ccgtctgcaa tacgaacatt ttgcatctga tcctcacgca acccctcacg aatctccaag
     5221 gccacctttt gcggttggtc aaagaactga taggctgcta gattggcaaa attcaagaga
     5281 ttgaccttgc ccgccatcac aatgttttcg ttgaacattt ccttaaagat gtgttcaaag
     5341 agatcgatga cattatccgt tgttgtaaag taacgctgga taatctgcgg aatctccgtc
     5401 cgaatcttgt agtgaatatc taaaacggtg tgaccgagga aacgttcctg aatgatgctc
     5461 ttcagtttca gcaaatcctc ctgcaagaag ttccttggaa tcagaaactg actagtaacc
     5521 gttcgcgact cgtctagggt aaataccgcc aaggctgtat gttgccccaa aacaacgata
     5581 tcaaaggctg tcaaacgttg cctgctcggc tcaacatcca gtgccactac cgtacagcca
     5641 ctcaggtctg ttagcaagtt agcagcctct tgcagaatat cctccaattt gaagaattcc
     5701 tgatcaaagg ctttgacaat ctcatatacc tcattttcag ccagccggtg aaaatccagt
     5761 gagtgtttca catagtactg aaaaccagca acacttggca tccgaccgct tgaagtatga
     5821 gccttctcaa gcaacccttg tttttctagt tccgccatgt cattacgaat ggttgcactg
     5881 ctagagttaa tagactcttg caaggctttt gatccgacag gttcgtgcgt tttggtaaag
     5941 atgtcaataa tcagatttaa aatatcctgc tgacgctctg taaccatctc atcactcctc
     6001 tctgtctgat caattagcac tcaatgcatc caagtgctaa cttatgattc tattatacac
     6061 ccttagaaga gaatgtcaag acaaaaactc aaaaaattag cactctttta tcaagagtgc
     6121 taaaaatcaa tctgaagacc tagaaccttg ctattcatct actcggtatt tcctttttag
     6181 tctgaaataa ccatgaatta gataagaaat cagaaaagca tataaaacaa aaataagaaa
     6241 gaaagacata gaaagatcct ctctaaacaa actcgtacaa acaacaagac cacctaagaa
     6301 agtagctgta caggaacgaa gtctagatcg cataacttcc catttgagcc ccttactcat
     6361 atagacttga tcctctggaa gtaaatcaga agacgattta cgaagaatcg aacaagaacc
     6421 tgctcctatc aattcccaac ctctatctct aaaatcttgc agttcatgct tatatttttt
     6481 aagaaatcta gaatcataga tacggtagat gacatcgtct ggttgacatt ggtcaaaata
     6541 gaacaaacca aaacgactcg ttctatacct ccaacctttc aaatgcatct catgtaaata
     6601 ttcttctttc ttgtccaaat caacaatggt gaaaatccga aattctactc tgctattcat
     6661 tgtcttaccc caaaattaga aaacatgcct agcgttattt attagataat tctttccact
     6721 tttgactcaa tctccaaaaa atataagaaa tctgaatcgc aaaaactatc aataaaaccc
     6781 aatctattat gaaaatcaaa aacacttccc aactgaaaga actacctcca gtgacaaact
     6841 ttgagaaaaa cggtagtaga gctaaaaaga gaagcaaaat aggaagcatc cgcattgtta
     6901 aaatccgttt ggcataaaaa aatctttatt taaacgaaaa tattatggca aaatttacgc
     6961 cagtttttga acggctgatg tagatatttt atactttcaa aatgtttaaa tgtgattatt
     7021 tatttttgaa aaatagctca ccagcccgac tgaaagtgct tatagaatga taataagtcg
     7081 cctgccgaaa acagcggaaa atagcggtgt tatgcggaga taatctgacg cgatgcgaaa
     7141 gtatattgca tacttatttt caacaattta gcagagtatt tttataagtg tgatataata
     7201 gaagtataat ttgttctgat agtttatttt atggagaagt agatttttag aatgcggagg
     7261 gttcaatatg gttgagttta taaagtctaa gaaagaaatg agtgaggagg atattaaagc
     7321 aaatttcatc actcctgcta ttgtatccaa aggatggaaa aatggtgagc atatcgctta
     7381 cgaagaatac ttcactgatg gtcgaattga ggttagagga gataaggctc gtcgtaaaga
     7441 aggaaaaaaa tcagactatt cactgtatta ccaatttgga actcgaattg caattgttga
     7501 ggcaaaggat aataaacaca gcgttcgagc aggattacaa caagctattg aatatggaga
     7561 gattttagat gttccatttg tttattcttc aaatggtgat ggctttattg aacacgaccg
     7621 tatcacgaga gaagaacgtg agctggagtt agacgaattc cctactcgtg aagaattatt
     7681 ttctcgtatg acgaaggaaa aaggattgac gtacgaaatt acagaagcta tctaaactcc
     7741 atactataca gacgccttct caatgaaaac gccacgctat tatcagcaaa tagctatcaa
     7801 ccgtactatt gaaacagttg ccagaggaca aaaacgagta atgtttgtga tggcaacagg
     7861 aacggggaaa acgttcatgg cttttcaaat tattcatcgc cttcgaaaag ctggtttggc
     7921 taaacgagtt ttattcttag cggatagaaa catcttagta gaccaaacga tggctgaaga
     7981 ctttaagcca ttcgaaaagg taatgacgaa aattacacca aaacttttga ctgctcctga
     8041 aaaattaaat tcttttgaaa tttatctagg gctttatcag caactaactg gtgaagatgg
     8101 aactgaaaca cattatcaaa aatttgacaa agacttcttt gatttaatcg taattgatga
     8161 agcgcaccgt ggttcagcta aggaaaacag taactggcgt aagataattg attatttcag
     8221 ttctgcgaca cagattggga tgaccgctac tcctaaagaa accaagaatg cttccaatac
     8281 ggaatacttt ggtgagccaa tctatactta tagtttaaaa cagggaatcg aggatggttt
     8341 tttggctcca tatcgtgtta tgagggttaa tttagatgtg gatgtggatg gttatcgtcc
     8401 agaaactgga aaagttgata ctaacggaca attaatagaa gataggtact acggcaggaa
     8461 agattttgat aaaaccattg tcattgatga tagaacgcaa agagttgcca agtttgtttc
     8521 tgattatatg aagcaaagca atgcacgatt tgataaaaca attgtttttt gtgttgatat
     8581 tgaccatgcc gagcgaatgc gtgctgcact tgtaaaagag aatctagact tagtccaaga
     8641 agactatcgt tatgtcatgc aagtaactgg tgacaacgct gaaggaaaag ctcaactgga
     8701 taactttatg gatgtcaatt ctaattttcc cgctattgta acaacgtcta aattattaac
     8761 gacaggagtt aatgctaaaa catgtcgttt gattgtttta gactctaata tccaatccat
     8821 gactgaattt aaacaaatta ttggtcgtgg cacacgtctt tatcctcaaa aggggaaaga
     8881 attttttacg attattgatt ttcgaaatgt taccaatttg tttgctgacc ctgattttga
     8941 tggtgagcca gtgaaggtgc tggaaacagg tgcgaaaaca gtcagtggtt ccacgcccgg
     9001 tttcgtagat gaggaaggtg acccagtaga aaaatatatc gttacagaca agcaggttac
     9061 cattcttaat tctactgttc aagtattgga tgaaaacggg aaactgatta ccgaaagcct
     9121 gaccgactac actcggaaga atatcttagg tagctacgcc actttgaacg attttatcac
     9181 agtttggcat acggcggata aaaagaagct tatcttagac gaactttata aaaaaggagt
     9241 ttatctagat gctattcgag agtcggaggg aatatcagaa caagaaatcg atgattttga
     9301 tttactccta aaacttgcct atggtcaaaa agaattaacc aaaacggaac gtatcaataa
     9361 actcaaacaa agcggatatt tatataaata tagtgaggaa gcgcgtgctg ttttggaaat
     9421 tttactgaac aaatacatgg ataaaggtat tggagaactc gaaagcattg aaacattaaa
     9481 acttccagaa tttcagatat atggtggaac cttcaaaatc atcaatactt attttggaga
     9541 taaaaaacga tatttacaag caattaaaga attggagcaa gagctattta cagtagctta
     9601 atgaaaggaa agtatgtcaa ttacatcatt tgtaaaaaga attcaagata tcactcgaaa
     9661 cgatgctggt gttaatggtg atgctcaacg tattgagcaa atgtcttggt tattattctt
     9721 aaaaatttat gatagccgtg aaatggtttg ggaattagaa gaagacgagt atgagtcaat
     9781 tatcccagag gaattaaaat ggcgaaattg ggctcatgct caaaatgggg aacgggtatt
     9841 gacaggcgat gaattacttg attttgtcaa taacaagtta ttcaaagagt tgaaagagct
     9901 tgaaataact tcaaatatgc ctattcgaaa aacgattgtt aaatcagctt ttgaagatgc
     9961 gaacaactat atgaaaaatg gcgtcttgtt acgccaagtc atcaatgtta ttgatgaagt
    10021 tgatttcaat agccctgaag atcgtcattc gtttaatgat atttacgaaa aaattcttaa
    10081 agatattcaa aatgctggga actcaggaga attttatacg ccacgtgcag cgactgattt
    10141 tattgccgaa gttcttgacc caaaacttgg agaatcaatg gcagaccttg cttgcggaac
    10201 aggaggcttc ttgacttcga ctctgaaccg tttaagtagt caacgtaaaa ctagtgaaga
    10261 taccaaaaaa tataatacag ctgtttttgg tattgaaaag aaagcatttc ctcatctttt
    10321 agcagttaca aatctgtttc ttcacgaaat tgatgaccct aaaattgttc atggaaatac
    10381 tttggagaaa aatgttcgtg aatatacgga tgatgaaaaa tttgacatta ttatgatgaa
    10441 tccacctttt ggagggtcag aattagaaac aataaaaaat aactttccag cagaattacg
    10501 gagttctgaa acagctgatt tatttatggc tgtcattatg tatcgtttga aagaaaatgg
    10561 tcgtgttgga gttattttac ctgatggttt tctatttggt gaaggtgtaa aaactcgctt
    10621 gaaacaaaaa ctggtagatg agttcaactt gcatacgatt attaggttgc ctcatagtgt
    10681 ctttgcaccg tatacaggaa tccatacgaa cattcttttc tttgataaaa caaagaaaac
    10741 agaagaaact tggttttatc gtttagatat gccagatggt tataaaaatt tctcgaaaac
    10801 taagccgatg aagtcagaac acttcaatcc tgttcgtgac tggtgggaaa atcgtgaaga
    10861 gattctggaa ggtaagttct acaaatctaa atcatttaca cctagtgaat tggctgagtt
    10921 gaattataat ttagaccagt gtggttttcc aaaagaggaa gaggaaatct taaatccctt
    10981 tgagttgatt cagaattatc aagcggaaag agcaacttta aatcataaga ttgataatgt
    11041 attagctgat attttgcagt tgttggagga caaataatga caccagaaca acttaaagca
    11101 agtattctcc aaagagcgat ggaagggaaa ttagtgccgc aaaatcccaa tgacgaacct
    11161 gcaagtgaat tattaaagag aattaaagct gaaaaagaaa aacttatcag tgaaggaaaa
    11221 atcaaacgag ataaaaagga aactgagata tttcgtggtg atgatg
//
LOCUS       DAVBOM010000063        11085 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBOM010000063 DAVBOM010000000
VERSION     DAVBOM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.063"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ878_001850"
     CDS             <1..116
                     /locus_tag="VQ878_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3096149.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VQ878_001851"
     CDS             140..1063
                     /locus_tag="VQ878_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HET3096150.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDGKFNLLFEQDGQISPDKGITIEVENEIYYILGSSIYRITIDESVEEIC
                     IGDFDFQLESGYGCYYNGHLFFGFQESYLFNIETKELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYIFEKDKWEKLEFELPSSVLGASSIQINESDLLILGGFNE
                     IAYNKAVIDLATPGYREEYFSKGRDFFNWNRSLRILDLETGKVDIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VQ878_001852"
     CDS             1145..2773
                     /locus_tag="VQ878_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3096151.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDSSESGKEKVFYL
                     SGLLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGNFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLTKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2882..3832
                     /locus_tag="VQ878_001853"
     CDS             2882..3832
                     /locus_tag="VQ878_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3096152.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFTSGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3849..4700
                     /locus_tag="VQ878_001854"
     CDS             3849..4700
                     /locus_tag="VQ878_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3096153.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4713..6695
                     /locus_tag="VQ878_001855"
     CDS             4713..6695
                     /locus_tag="VQ878_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096154.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIKMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHEITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKESLKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6705..8114
                     /locus_tag="VQ878_001856"
     CDS             6705..8114
                     /locus_tag="VQ878_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096155.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDIKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8119..8607
                     /locus_tag="VQ878_001857"
     CDS             8119..8607
                     /locus_tag="VQ878_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HET3096156.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8895..9302
                     /locus_tag="VQ878_001858"
     CDS             8895..9302
                     /locus_tag="VQ878_001858"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3096157.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYFPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGTSQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9334..10251
                     /locus_tag="VQ878_001859"
     CDS             9334..10251
                     /locus_tag="VQ878_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3096158.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKDVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEEAAALIRETKERFL"
     gene            10278..10472
                     /locus_tag="VQ878_001860"
                     /pseudo
     CDS             10278..10472
                     /locus_tag="VQ878_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(10622..>11085)
                     /locus_tag="VQ878_001861"
     CDS             complement(10622..>11085)
                     /locus_tag="VQ878_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3096159.1"
                     /translation="YAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHT
                     KYQKTQTDFQQKIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQR
                     KIDVEPVFGQIKACLGYKRCNLRGKRQVRIDMRLVLMANNLLKYNKRTTQN"
BASE COUNT         3694 a         1665 c         2114 g         3612 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggaatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 cgggaaattt aatcttctat ttgaacaaga tggacagatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tgatgaaagt gtagaagaaa tctgtatcgg ggattttgat ttccaactag agagtggtta
      481 tggttgttat tataatggcc acttattctt tggatttcag gaaagttatc tgttcaatat
      541 tgagactaaa gaacttttta aaaaatctga cttcccagtt tctggtagag gacaaggttt
      601 atcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatattt ttgaaaaaga taagtgggaa aaacttgagt ttgaattacc
      721 aagttcagtt ttaggagcgt caagtataca aataaatgaa agtgatttat taatccttgg
      781 tggctttaat gaaattgctt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatac ttttctaagg gaagagattt ctttaattgg aatcgtagct tgcgaatact
      901 agatttagag acaggtaagg tcgatattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat tcttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gtttgcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatgggtt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 taactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa ctaaaaaacc aattgatata ctattctatc gctactttat
     2041 cgctaactta gcaggtgttg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tgtttattga atcatgtatc tctcactctt gttttttcag gagaaattaa
     2881 aatgaaaaaa tatattctaa aaaaagtatt attcatgatt cctatgttgt tgattattag
     2941 ctttttagta ttcattgcac tagatttaac accagcagat ccattgacat atatggtatc
     3001 tccagatatg gctagtagtg cagaacaaat cgaaaagcta agacagcaat taggtttaaa
     3061 tgatccagta ttagttcgct atggaagatg gctttggcaa ttactccatg gtgattttgg
     3121 atacagtatt gtaaatggta acccaatttc caaaattgta ggacaagcat tgcctgcaac
     3181 ttttgaatta gcttttgtgt cattaattat ttcaacaatt gttggtattg taattggggt
     3241 tatatcagcc gttaaacaaa atggtattat cgataatgtt gctcgttttc tagctgttat
     3301 cggaactgcg attccacaat ttttctttgg tattttaatt ttaaacttct ttgcaattca
     3361 gttaagaatt ttacctattg gtggtagatt taccagtgga gattttacat ttattaatag
     3421 agttgaacac ttaattctac cagtaatggc tatgtcaatt gcattggtag ccgctttaat
     3481 gagatacaca cgtaattcta tgttggatgt ttttaatgca gattatgtta aaacagctcg
     3541 tgcaaaaggt gttcctgaat ggaaagttta ttttaaacac atatttagaa atgctatgcg
     3601 accaatttta gtgttattga ttttccgtct accaatgtta attggtggat cagtaattat
     3661 cgagagtgtc ttttcttggc ctggaattgg ttctatcatc ctatctagtg taacagcagg
     3721 tgactatcct gtaattatga ttaccacatt aatgatttct gtcgtagtgt tatttgctag
     3781 tctacttgta gatattatgg ctgcaatatt agacccacgt attcgttatt aggaaggagg
     3841 tcaatgttat gaaacctatg cctttatgga aaagaaattt gaaaaaattc tataataaca
     3901 aattggcctt tatcggcttt atatgcttca tgctaattct attagcatgt attctagcac
     3961 ctttattgac aacctattct ccagatgttg ttgatttagg atctatgaac cgtcctcctt
     4021 cagcaaaaca cattctggga acagataaac taggtcgtga cgtatttgct cgaatcctat
     4081 atggtggtcg agtttcaatt caagtaggga tgtatggagc gatttgtgga gcggttattg
     4141 gtactgtact tggtggtatt gctggatatt ttggtgggaa aattgatgct cttctagttc
     4201 gtctagcaga attattctta acattcccga atatgattgt cattctcttg ctttcaagta
     4261 tttttggaca aggtgtattc aatcttatct tcgtattctc agtaatgggt tggatgacaa
     4321 cgttccgaat ggttcgtaat gagttcatgt ctttgaaaca agaaacatat gtggatgtat
     4381 gtagagcttt tggtttttct gacagtcgaa ttatctttaa taatatttta agaaatgcta
     4441 tctcaccagt aattgtatcg ttgtctttaa acgttgctgg tttcattctc agtgaggcag
     4501 gtcttagttt cttaggagta ggtgttcctt ctgatattcc tacttgggga aatatcataa
     4561 atgctgccaa aacagccgat gttattaaaa atagttggtg gctgtggtta gttccagggt
     4621 caatcattac tcttttcgtt ctttctatca actttattgg tgatggatta cgagatataa
     4681 tggatccgaa acaacagtag gaggttgaca aaatgaatca aacagtttta gatgtaaaaa
     4741 acttaaaaac tgaattcatc actgataaaa aagcatttcc gattattaaa gatgtaaact
     4801 tcactttgga aagagggaaa gttttaggga ttgttggtga atctggatgc ggtaagagtg
     4861 taacagtgaa tacagtgtta aacttattac ctaaaaatgg acgcattgct gaaggtgaaa
     4921 tcacatattt cgatgaagat aagccgatag agcttcaaaa attaaagcaa tatggtaaag
     4981 aatttcgaaa gttacgtggt gaaaacatat caatgatttt ccaagatcca atgtctgcat
     5041 tgaatccagt atatacaatt ggtaatcaaa ttactgaagt ccttcatgaa cattatgaca
     5101 tttctaaaga ggaggcaaat aaacgtgcta taaaaatgtt agaaaaactt ggaattcata
     5161 atgctgcaga acgcatgaat gactatccac accaatttag tggagggcag cgtcaaagaa
     5221 tagtcatagc gattgcaatg gtatgtaatc cagatattct aattgcagat gaaccaacaa
     5281 ctgcccttga tgtaacaatc caagcacaaa tacttgattt acttgatgat ttacgtaaag
     5341 agcatggaac ttctattatc ttaattactc acgatttagg cgttattgct caaattgcgg
     5401 atgaagttgc agtgatgtat gctggtgaag tcgttgaagt tggaactgta gctcagatct
     5461 ttgatcaacc taaacacccg tatactcgtt ctctattaag atctattcct aatcctgaaa
     5521 atatggataa aaagctacat gttatccagg ggagcgtacc ttcaatttct gaaatatctg
     5581 aaaaaggatg cagattcgca aatcgtattc catggttaga aaaagaacat catgaagaag
     5641 aacctcaatt gcatgattta ggtgacggac attttgtaag gtgttcttgc tataaacatt
     5701 tctttttcga agataaggaa gaagaaacat tagcggaaaa acatgtaggt aatgttgttt
     5761 tagaagtaaa aaatattaaa aagtactact atcctaagaa acaactattc aagccactag
     5821 gttctccgtt gaaagcactt gatgacgtat ctctagagtt aagaaaagga actactattg
     5881 gtatcgtagg agagtctgga agcggtaaga gtacgattgc gaaatcatta atgaaactcc
     5941 atgagattac agatggtgaa atcaatattg atttgaatgg gaaaactcaa aatatttatg
     6001 gaattaaacg taaggaagat ttggatttcc gtaagaaagt tcaaatggta ttccaagatc
     6061 cttatgcatc attgaaccca actaagaaaa tttataattc atttgatgaa ccgatgattg
     6121 tccataatat tggaaacaaa gaggaacgct ttgaacgtat gaaagaatcc ttgaagatgg
     6181 taaacgtgcc agttgagtac ttggagcgtt atcctcatga attttcaggc ggacaacgtc
     6241 aacgtttatg tattgctcgt gccctttgta tgaaaccaga aattttaatt ttagatgaac
     6301 ctgtttcagc attagatcta tctgtacaag cgcaagtttt gaattatctt gttgaaatcc
     6361 aaaataaaga agatttgact tatgtattta tttctcatga cctaggtgtt gtgaaataca
     6421 tgtgtgacta tctatatgtt attcataaag gacgtattgt agaagctggt tctcgagaag
     6481 atatctacaa taacccaatg catatttaca ctaaaaaact attagctgct attccagaag
     6541 ttgattatca cttcaaagag gcattggcaa caaaacgtaa agaaaatgaa gttgaattta
     6601 aagcacagta ccatgaattt tatgatgaag atggccgtgc ttatgatctt aagcaggttt
     6661 caccaacaca ttttgtagcg ttaaaaccag aataggtggt aaatatgaaa ttaaataaaa
     6721 aaatatattt ctttgataaa ggaattttta atccttatcg aatgagtaat gtaaaattaa
     6781 aagttaatca ggcagtaaag gataaagaaa ttttcttcac tgaggaaaaa ccatgggaaa
     6841 ttcgttttga taacagttat ccaaatgttt tctttgatga tttagcaggt gtttatcgtt
     6901 gctactattc tacatttact gatgatgagg agtctgaaaa atactcttta gaggagcgta
     6961 aggaacgtca atatctacct cgtgcgaagc gtattgtttc actttgttat gctgaaagta
     7021 aagatggtgt taactgggtg aaaccaaatc taggtattac agaatttcga ggatcaactg
     7081 aaaataatat tatcggacat tttttacatg gtacatctgt ttttctagat aaacatgacg
     7141 cagatgaaaa tcgtcgttat aaaatgttta caaagattga ttacggtaac ggtgttcatt
     7201 ttattgctgt agcattttca aaagatggtc tacactttga tgaatacatt aaagtaccaa
     7261 acttcaatcc acgtgcagac actcataacc atatcatata tgatgaagca ttaaatcgct
     7321 atgtgctaat tactcgtact tggagagatt cattgcgctt gccgtgtgta tctacgagtg
     7381 ctgatttcat taactggact ccaattcaag aaattttgaa tgtctgtgat tatgaaaatc
     7441 aaatttattc tatgcctatt tttaaacgtg gcgattatat actaggttta gcttcagttt
     7501 tccatgaagg agatcaactg aacaagaatt acgatacagt ggaccttcaa ttgacttata
     7561 gttatcgtca tgttggttgg cattatctaa acactgatac tccacttatt cctcgtggta
     7621 aaggtcaata tggtgatgga gaatttgact gtggatgtat ctattcttct gcaccagtta
     7681 ctatcggtga ccgtacttat ttctactaca tgggaggaaa tggacaacat acaaacttcc
     7741 gtgaaacaag cttgtctcgt gcttatattg agaaagatca ctttgcatat tgggatatta
     7801 aacgtccaga atatccaggt gttttgtata ccaatggatt tattttcctc aatgatcaag
     7861 tttaccttga tgcagatatt gcagctggag gctttgtaac aattgaattg ttcgagaata
     7921 atcacactcc aatggaaatt acagcttccc ttgaaaaaat agaagatggt cgctatcaag
     7981 tgttattcag cgaaccttta cctcgaactc aaactcgact gaaaattagc tttaaaaatg
     8041 ctaaaatcta cgcaatcgaa ggaaatttag atattttcag aattgaatca gacaatgctc
     8101 tattgagggg gtaagattat gaaatatgat ttatatgata attgtattga acttctaaaa
     8161 gaacgcgaag ttacaattga agatatggca gcgttagtaa tattttcaca acaaaaatat
     8221 taccctgaat taactcttga cgacgcttca tatgcaattc aacgtgtact aaaaaaacgt
     8281 gaagttcaga atgtaattat gacaggaatt gagttagata agttagctga agcacaaaaa
     8341 ctatctccag aatttcaaaa gattatggag aaagataatc cattgtatgg gattgatgaa
     8401 gtaatcgtct tatcgatatt gaatttatat ggttctattg cctttacaaa ttatggctat
     8461 ttagataaat taaaaccact gattttagaa agattgaatg agaatcacga aggtgtttgt
     8521 aatgtatttc tagatgatat tgttggtgca atagccgcag cagcatgtag taaaattgca
     8581 cacaatcatg ctagtgatga aatataacta ttgaatttag tatcgtaaat aataaagcgt
     8641 ttggtttcta gattattgtc attcaaattg gataatgata aatctagaaa ccaaatatat
     8701 tttccgcata aaatgaggga ttatatatct cactttttta caattgtata gtggattaaa
     8761 actagaatag tgcatctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8821 tgatttgtac tgttcttatt tcattttact ataatttagt gtgagtaaaa tataataata
     8881 aaggagttaa aacaatgaca gtaattaata aatttgtttt aatggagcaa gcaaaaaaag
     8941 ttttaaaaaa tgcttacttt ccgtattcca aatttcctgt aggtgcagca attttattta
     9001 aagatggtaa agtaattaca ggagcaaata tagaaaatgt atcgtttggt gtaactaact
     9061 gtgcagaacg tagtgctatt ttttatggga cttctcaagg atatagaaaa ggagatattc
     9121 ttgcgattgc tgttgcaggt gaaactgaag actacttacc accatgcaac atttgtcgtc
     9181 aagttatggt agaattttgt gagcctgata ccttagtctt tctattaaat ggtaagggaa
     9241 acatacttga attgcgatta gaggaattag tcccatattc gttctcaagt ctagaaatgt
     9301 aattacgtag tatgaaataa ggagaaaaaa acaatgtcag atttgaaaaa atacgaaggt
     9361 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
     9421 cgtgccttgg ttcaatactt cattgataaa gatgttcaag gtctttatgt caatggttct
     9481 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
     9541 gcggtagcca aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagac
     9601 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
     9661 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
     9721 gcagctccaa acacagacta cgttatttac aacattcctc aattggcagg ggttgctttg
     9781 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
     9841 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc
     9901 tttaatggtc ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc
     9961 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    10021 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    10081 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    10141 ttgaatattg gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    10201 gtagaagaag ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atccataagg
    10261 aggtatttat gacgcactac gttgccaatc cagaggtggt cattctcggg ggtggcatca
    10321 tgggacaaga agctatcctc aaaccaaaga ttcgtgcagc cttgaaagaa gccttggttc
    10381 caagtttggc tgagaacaca agattagaat ttgctcatca tcaaaacact gctgatatgc
    10441 ttggagccta ctatcatttt aaaataaaat aaatttaata tttactttac taaattagtg
    10501 tattcttcct actttaatta gagaatgatt taagttctct ttaaaaatca aaagagtcta
    10561 ggataaaata gttctcaatc acaaaaaagc taaagatttc caattgtgga actctagctt
    10621 tttaattttg agtcgttctc ttattgtatt ttaggaggtt attggccata agtaccaatc
    10681 tcatgtcaat tctcacttga cgcttccctc tcagattaca tctcttgtaa cccaaacaag
    10741 cctttatctg cccaaagaca ggttccacat caatcttgcg ttgagcgaaa atctgtctac
    10801 cttggggaga taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca
    10861 tatacagtcc cttttgaggg gctgattcag gttcgtcggc gtagtaaacc ttgatttttt
    10921 gttgaaagtc tgtctgtgtt ttctgatatt tggtatggtg aaaacgataa taccagccat
    10981 caggatgtgt atagctatcc tccttgtcat tatagtgcca attcgctaag tttctagctg
    11041 actgtttata gcctctcttt tgttccttat caaacatggc atatt
//
LOCUS       DAVBOM010000064        11007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBOM010000064 DAVBOM010000000
VERSION     DAVBOM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.064"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(128..1759)
                     /locus_tag="VQ878_001862"
     CDS             complement(128..1759)
                     /locus_tag="VQ878_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET3096160.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6992
                     /locus_tag="VQ878_001863"
     CDS             2052..6992
                     /locus_tag="VQ878_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET3096161.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGS
                     ALAPLLEKNKVLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7082..8278
                     /locus_tag="VQ878_001864"
     CDS             7082..8278
                     /locus_tag="VQ878_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET3096162.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8414..8941
                     /locus_tag="VQ878_001865"
     CDS             8414..8941
                     /locus_tag="VQ878_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3096163.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9018..9374
                     /gene="glnR"
                     /locus_tag="VQ878_001866"
     CDS             9018..9374
                     /gene="glnR"
                     /locus_tag="VQ878_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET3096164.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9411..10757
                     /gene="glnA"
                     /locus_tag="VQ878_001867"
     CDS             9411..10757
                     /gene="glnA"
                     /locus_tag="VQ878_001867"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET3096165.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10847..10966)
                     /locus_tag="VQ878_001868"
     CDS             complement(10847..10966)
                     /locus_tag="VQ878_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET3096166.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3512 a         2037 c         2414 g         3044 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta aaaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtaagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 ctttcttagc atttcctaga gcgatagatg gggcctgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga caactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccagt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgattttttg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatactatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ttattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgaaaac
     1921 agctattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttcttgaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgttggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatact agagaaaaca
     2281 agctagaaaa ggcagaagga gtagcgacag catctgaaac tgcagaagca gctagcgcag
     2341 ctaaaccaga ggaaaaagca ggtgaggtgg ttgcagaaac accatctgca gaagcaaaac
     2401 ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta
     2461 aaccagcagc agaagctaat aagactgaaa aagaagtcca gccagatgtc cctaaaaata
     2521 cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa ttgttaaaat
     2581 gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc ctcgcttcac
     2641 gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt caagccttat
     2701 caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag ttcaaggcct
     2761 atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt ctcgtaccaa
     2821 ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt acactcttct
     2881 tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg aagcaagacg
     2941 cagatggtag cttcccaatt gcccgtaaat tggtagacat ggccaagtat tatggctatg
     3001 atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt ggagaaaaga
     3061 tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt
     3121 attcttggta tgatgccatg acctataact atggacgtta ccatcaagat ggtttgggag
     3181 aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat aacttctttg
     3241 ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc aactggattg
     3301 gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt tcctacaaga
     3361 caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt tctcttggtt
     3421 tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat cataaaaatg
     3481 aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca ggtgacaaag
     3541 attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt aatactttta
     3601 ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag gtttctaagg
     3661 attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc tggtggcaga
     3721 cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat aatggcggaa
     3781 attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg agactttatt
     3841 ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag ggaggaaaag
     3901 gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat gatgcagatg
     3961 catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgat ctcagctcac
     4021 tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt gctgtaaaag
     4081 attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag ccacaatcgc
     4141 cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg
     4201 tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa gatggagaca
     4261 gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa gttagccgct
     4321 cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt aaaaatggag
     4381 ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa gataccagcc
     4441 taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat agtactttcc
     4501 ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt actagcttgt
     4561 cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg accaagccac
     4621 gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct gttaacgatg
     4681 gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt gagtggaagc
     4741 tagctaagga agtccgtggc aacaaagcac acgtgacaga tatcactctt gataaaccaa
     4801 tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact ccatggaagg
     4861 ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt gtcaatattc
     4921 cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt ggctttgcag
     4981 atgtacaggc tggagcaact attaccgttt atgataatcc aaattctcaa actccgctcg
     5041 caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat ttgacaaatc
     5101 aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt aatgtcctag
     5161 cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa acaggaccta
     5221 agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt cttcgagttc
     5281 agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt gtatcagtat
     5341 caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat ttgggacaac
     5401 cagtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt ccgaaaacta
     5461 ttttgggaat tgaagtaagt cagaaaccga aaaaagatta cctagttggt gatagcttag
     5521 acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa gaacattcct
     5581 ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt cgtcaaacct
     5641 tgacgcttcg ttaccaaggt catgaagtca actttgatgt tttggtatct ccaaaagcag
     5701 cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct aagaacaagg
     5761 tggtctataa ctttgcttca ccagaagtaa aagaagcttt cttgaaagca attgaagcgg
     5821 ccgaacaagt gttgaaagac catgaaatta gcacccaaga tcaagtcaat gaccgactta
     5881 ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttaag gaagaaaaga
     5941 cagagcttga tcgtttaaca ggtgaggttc aagaactctt ggatgccaaa ccaaaccatc
     6001 cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggtcttggtt gaaaaagtag
     6061 atttgagtcc agaagagctt gcaacagcga aacagagtct aaaagatctg gttgctttat
     6121 tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa gtacacttct
     6181 caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg
     6241 aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg
     6301 aaaaaggtca agatgttgat ctctcttacg cttctattgt gaaaatccca attgaaaaag
     6361 ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta gaattggctt
     6421 ttgaacaaac ggatagtcat gttatcttta cagcaccaca ctttactcat tatgcctttg
     6481 tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac aaagtccttc
     6541 caaaacctac ttatcaaccg gcttctgatc aacaaaaggc tcctaaattg gaagttcaag
     6601 aggaaaaggt tgcctttcat cgtcaagagc atgaaaatgc tgagatgcta gttggggaac
     6661 aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa gttgatgaaa
     6721 acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca gaaattgttg
     6781 aaattggaac aaaagtaaaa acagtaccag cagtagtagc tacacaggaa aaaccagctc
     6841 aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca ggaacagctg
     6901 atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt ttagccttga
     6961 ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg aaatctttcc
     7021 ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga gtttttgtaa
     7081 catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt
     7141 tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta tcacagcagc
     7201 tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt tctctcacct
     7261 tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg tagcagctga
     7321 cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt
     7381 ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa acactcgtta
     7441 cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta aatactgggc
     7501 atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc gtgcacacgc
     7561 atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa
     7621 cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg tggctatcct
     7681 tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg aaaaagctga
     7741 taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag gtatcgaaat
     7801 cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc
     7861 aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg ctggttacac
     7921 tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg
     7981 tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag ttgtatggaa
     8041 cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg gtgtgatgga
     8101 cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact cagctgccgc
     8161 agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg gtggagcatc
     8221 aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag aaaaataaga
     8281 ttttataaat aaatcaaaga agagagggat gaaagttcct cttttctttt gcttaaaata
     8341 aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa aatggaaata
     8401 gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc agttcaaact
     8461 tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga tttttggctt
     8521 ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc tgagggagag
     8581 ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta tcggtggact
     8641 ctatgccttg gtcttcttct tattaaatac ctttttccat gaagcctttt gggtgacctt
     8701 ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca tgaataacaa
     8761 agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa ttccaagtgg
     8821 tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc
     8881 aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata
     8941 atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta taatagacag
     9001 aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct gtttttccta
     9061 tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat tatgaagatc
     9121 aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca
     9181 tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc gctgccatta
     9241 agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag actgaagtac
     9301 gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta cagtcacctt
     9361 ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt atgccaatca
     9421 cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt
     9481 tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat gaacagttag
     9541 ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt tttgtacgta
     9601 tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc ttcccttggg
     9661 gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca gaaggtgaac
     9721 catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg gaagaagttg
     9781 gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag ttggatgaaa
     9841 atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg gcacctactg
     9901 accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag
     9961 tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt aagtacgatg
    10021 aagttctccg tgcttgtgat aagattcaaa tctttaaact tgttgttaaa accattgctc
    10081 gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt gctggctcag
    10141 gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc tttgatccaa
    10201 atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc ggtttgatca
    10261 agcatgctta caactatact gccatcatga acccaacagt taactcatac aaacgtttgg
    10321 ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt tcgccacttg
    10381 tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa
    10441 tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat ggtattgaaa
    10501 ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca gcagaagagc
    10561 gcaaggaagc tggtattaca gaccttccat caactcttca taatgctttg aaagctttga
    10621 cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc ttccttgaag
    10681 ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa attgataatt
    10741 atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt
    10801 ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg
    10861 aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatca
    10921 aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact
    10981 tcaaatcgaa atctacaagt ttactaa
//
LOCUS       DAVBOM010000065        10754 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBOM010000065 DAVBOM010000000
VERSION     DAVBOM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.065"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(117..1541)
                     /locus_tag="VQ878_001869"
     CDS             complement(117..1541)
                     /locus_tag="VQ878_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3096167.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ878_001870"
     CDS             complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ878_001870"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET3096168.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ878_001871"
     CDS             complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ878_001871"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET3096169.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6527..7705)
                     /locus_tag="VQ878_001872"
     CDS             complement(6527..7705)
                     /locus_tag="VQ878_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3096170.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQTIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7785..8648)
                     /locus_tag="VQ878_001873"
     CDS             complement(7785..8648)
                     /locus_tag="VQ878_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3096171.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8651..10552)
                     /locus_tag="VQ878_001874"
     CDS             complement(8651..10552)
                     /locus_tag="VQ878_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3096172.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRTILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEQTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3220 a         2371 c         1916 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaacggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaaccacaa ccctttttgc gaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaatccact
     1681 acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     1741 ctatagtaaa ataaaaaaac tgaacaattt ggtttgggac agtcaaacca atttctcaca
     1801 atgttttaga aacacgggtg tgctattcca atttcaggct actataactg tcatagattg
     1861 ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca aatgttcaaa
     1921 aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat acaagtgagc
     1981 tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta ccaatactca
     2041 taactgggaa tttttctgtg taaaaatagc gagatagatg gtatttataa aacactcaag
     2101 acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt ggttaccaac
     2161 atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt cacaaccacc
     2221 aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc aatcgccgaa
     2281 tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc accagttttt
     2341 gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc attaatcaag
     2401 ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc acgctctcta
     2461 tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg accaaattct
     2521 tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt ggcagtttcg
     2581 accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa taaatcgtga
     2641 agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg tgtatagctt
     2701 cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc agcaccactg
     2761 acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc gcgctgattg
     2821 tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc cttatcataa
     2881 ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt ggagtcgatt
     2941 tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc catcaagtca
     3001 aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc aatcatatac
     3061 ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc attctggaag
     3121 gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa tggtgcatca
     3181 acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc cgcatcgtga
     3241 taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc tggattagtt
     3301 gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt gtaggttaca
     3361 tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg aacataattg
     3421 tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt aactgttcca
     3481 gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga tgtaggtgat
     3541 ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt ttccaagcgc
     3601 caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc tacatggctc
     3661 agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc acgtgtcagt
     3721 gtttggtgat gagggaattg gacttgatac tgataagcct tacctaccaa atcttcctca
     3781 acatccaaac tccagacacc gattgtattg tccttatgat tataagagta gctattgcct
     3841 cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc ataaacgaca
     3901 acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt gtcctctaca
     3961 cggcaaccca attctccttg gtaaccccaa tgatggtcaa aactagcact gttaatggcc
     4021 ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc aggattttca
     4081 gagtaataaa tcctatcatc gccttccaaa atccagactt ctgttaatag gggatagtga
     4141 ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa attcaagctt
     4201 tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata atcttctttg
     4261 taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt gtcatattca
     4321 ccattcttgc gatggtaatg aatgcgcata gggtagttat acatttttta tttttccttt
     4381 ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt aacagacata
     4441 gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag ccatgcctca
     4501 tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc gtctgcacct
     4561 accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc cagactttcg
     4621 agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa taccacggtc
     4681 aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag attgacccca
     4741 gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata agtctgaaga
     4801 cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga atctgcctga
     4861 tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt gcttccgaca
     4921 tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga tgcttggata
     4981 gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag gaaatcctct
     5041 tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa aagcttctca
     5101 acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa gtgaatcaag
     5161 ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac ttcatcttca
     5221 aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag tttttcttca
     5281 gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc agccttatat
     5341 acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac attgtgcagg
     5401 gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc agttggagtt
     5461 acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc tttttcttca
     5521 gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc aagttcttct
     5581 tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg tagattttcc
     5641 cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc agccaagatt
     5701 cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt ttcttggcta
     5761 tcacgagttg aaggactggc ttcttgatag agaaacgttg caagattacg ctttgcaact
     5821 actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt agcaaattca
     5881 ggctctccat tttcttggcg cgcttggtta acttggtcaa aggaagcgcg tggcatgtaa
     5941 cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat gtccttaaca
     6001 cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt taccccagca
     6061 accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt cagctcacaa
     6121 atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc tagctcctca
     6181 cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt ttcaaaacca
     6241 tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg ctctggataa
     6301 gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc tgaaaccgag
     6361 ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac taactcattc
     6421 attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa acgagaaggg
     6481 cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat atcaattttt
     6541 caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca ccacttccaa
     6601 ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct tttgcaatag
     6661 gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct
     6721 caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac
     6781 aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc
     6841 cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta attttactag
     6901 ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc
     6961 cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga
     7021 aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt
     7081 gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa
     7141 cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg
     7201 agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag
     7261 gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag atcacaatct
     7321 catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag
     7381 caatagtctg cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta
     7441 tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac
     7501 gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga
     7561 gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc
     7621 agacactatt tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa
     7681 tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat
     7741 caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat
     7801 ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac atcaaaaata
     7861 tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg atataaggcc
     7921 aaacctttta aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc
     7981 ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc
     8041 tggtaacaat tgagggccaa aattaacact aatctcttat ggcgactaat ctcttggtaa
     8101 aattcctccc tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa
     8161 ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga
     8221 taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa
     8281 atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta
     8341 gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa
     8401 agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt ccttgcctta
     8461 tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa acgggagact
     8521 gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca ggattcgcct
     8581 gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga
     8641 tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac
     8701 gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt
     8761 ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta
     8821 gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat
     8881 agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac
     8941 tcatttctgc tgttactttc ttctcaacat agtagtcgta atctccaagg tagagagttg
     9001 aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat
     9061 gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac
     9121 tatcaatatc caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag
     9181 acaatttggc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt
     9241 taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg
     9301 tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt
     9361 gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa
     9421 acggaatttg atccacgatt gatttgataa aggttgattt tccgatacca ttgggaccaa
     9481 cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc
     9541 cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac gtttgttcag
     9601 actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa cgctccattt
     9661 tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc
     9721 gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct
     9781 cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat
     9841 ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt
     9901 cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga
     9961 tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa
    10021 ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca
    10081 tctgccacat agactcgtca aacttgaatc cattcaaaat cgttcgaata tcagcttcat
    10141 aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct gacatcagtt
    10201 tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct
    10261 ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta ttttcagact
    10321 caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc
    10381 cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat
    10441 ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa
    10501 gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag
    10561 tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata
    10621 acataaaata aactaaatta tgtatatttt atattagatt cttcactatc ttgttggatt
    10681 ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt
    10741 cattatttac gtac
//
LOCUS       DAVBOM010000066        10624 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBOM010000066 DAVBOM010000000
VERSION     DAVBOM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.066"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            389..1567
                     /locus_tag="VQ878_001875"
     CDS             389..1567
                     /locus_tag="VQ878_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3096173.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1881..2012
                     /locus_tag="VQ878_001876"
     CDS             1881..2012
                     /locus_tag="VQ878_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET3096174.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2033..3583
                     /gene="dltA"
                     /locus_tag="VQ878_001877"
     CDS             2033..3583
                     /gene="dltA"
                     /locus_tag="VQ878_001877"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET3096175.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3580..4824
                     /gene="dltB"
                     /locus_tag="VQ878_001878"
     CDS             3580..4824
                     /gene="dltB"
                     /locus_tag="VQ878_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET3096176.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4838..5077
                     /gene="dltC"
                     /locus_tag="VQ878_001879"
     CDS             4838..5077
                     /gene="dltC"
                     /locus_tag="VQ878_001879"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET3096177.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5070..6338
                     /gene="dltD"
                     /locus_tag="VQ878_001880"
     CDS             5070..6338
                     /gene="dltD"
                     /locus_tag="VQ878_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3096178.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6493..6933
                     /gene="adcR"
                     /locus_tag="VQ878_001881"
     CDS             6493..6933
                     /gene="adcR"
                     /locus_tag="VQ878_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET3096179.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6933..7637
                     /locus_tag="VQ878_001882"
     CDS             6933..7637
                     /locus_tag="VQ878_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3096180.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7630..8436
                     /locus_tag="VQ878_001883"
     CDS             7630..8436
                     /locus_tag="VQ878_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3096181.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8446..9951
                     /gene="adcA"
                     /locus_tag="VQ878_001884"
     CDS             8446..9951
                     /gene="adcA"
                     /locus_tag="VQ878_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET3096182.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
BASE COUNT         3056 a         2002 c         2251 g         3315 t
ORIGIN      
        1 actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc tgagacgacg
       61 atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag aaaagcttag
      121 agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc tctttttcga
      181 ttgaagatgt aattattcta ctaactaact aacttcttag tactagccaa caacgataat
      241 cataattcct cctaaaatta ggaataataa aggcaatagt ttttgttttt tcatgtaaaa
      301 aacctcactt ttgttttctg ctattttatg ctaaaatatt aaaaatcaaa tttaattcca
      361 aagtttgtaa ctaaaggggg agcgctacat gtctaattca tttgtcaagt tgttagtctc
      421 tcaattattt gcaaatttag cagatatttt ctttagagta acaatcattg ctaacatata
      481 cattatttca aaatcagtaa ttgccacatc actagttcct atcttaatag gaatatcctc
      541 ttttgttgcg agtcttttag ttccgttggt tactaaaagg ttagcgctaa atagggtttt
      601 atctttatct caatttggaa agactatatt attggcgata ctggtaggaa tgtttaccgt
      661 aatgcaatcc gtagcgcctt tggtgaccta tctatttgtt gttgcaattt ccatactaga
      721 tggttttgca gcacccgttt cctatgctat tgtgccacgc tatgcgaccg atttgggtaa
      781 ggctaattca gccttatcaa tgactggtga agctgttcaa ttgataggtt ggggattagg
      841 tggactcttg tttgcaacaa ttggtctgtt acctaccacg tttatcattt tagtcttgta
      901 tatcatttct agctttctga tgttatttct tcctaacgct gaagtggagg tgttagagtc
      961 agaaactaat cttgaaattt tgctcaaagg ttggaagtta gttgctagaa atcctagatt
     1021 aagacttttt gtatcagcaa atttattgga aattttttca aatacgattt gggtttcttc
     1081 cattatactt gtttttgtaa cggagttatt aaataaaacg gaaagttact ggggatattc
     1141 taatacagca tactctattg gtattataat tagtggctta attgctttta ggctatctga
     1201 aaagttcctt gctgctaaat gggaaagtat tctttttcct cttgtagcta tggcaatagt
     1261 gacactgact attctatatt ttccaaacgc acagatgttt ttattatttt cagctttagt
     1321 tggtatgtta tcgcaactaa aagaagttcc tgaaagtgta tttcttcagg aaacagtaga
     1381 ggaaaatcat ttagttaatg tctattccgt tcttgaagtg atttctacat tagcattttc
     1441 agtatttgtt ttgctaatga gctatattac tgagagtttt ggtattagca tcagtttttg
     1501 gctatcagcc atttgtctga tgatagaagc tattttaatt tatatcagac gagattattt
     1561 taaatgagag agtggttaaa aagtctttaa aaatcagaaa agcgcatagt atcaggtgtt
     1621 gaaaaaactt gatattgtgt gttttattat gggaagattt acttcattgt ctcctgaaat
     1681 ggagttttga ggcaggatca ctctatttga aaatatacat agaaaaactg tataatcctt
     1741 aaaataagct gaaatctatt ggaaacatac ggtaaacaat tgaaaagata ctatataaag
     1801 tggtacaatg gtagaaaaat aagctagtaa gaatcactct tattttagcg aaaaattaca
     1861 gaaatgaatg gtttttcttg atgaaacaga gaaaagaatt gtacctcttt cttggtcgga
     1921 cagccttgta ttttcttatc tttctagggc tgctttactt ctttagctat cttggtcagg
     1981 gtcaaggaag ctttatctat aatgaatttt aacttgaagg agaatcccta ttgtgtcaaa
     2041 taaaccaata gcagatatga ttgaaaccat tgagcatttt gctcagacac agcctagcta
     2101 tcctgtctat aatgttttgg ggcaggaaca cacttatggc gatttaaagg ctgattcgga
     2161 tagtttggct gcagtcattg accaactagg cttgcctgag aagtctcctg tggttgtttt
     2221 tggtggccaa gaatatgaaa tgttggcaac ctttgtagcg ctgactaagt caggtcatgc
     2281 ctacattcca attgatagcc attcggcctt ggagcgagtt tcagctattt tagaagtagc
     2341 agagccaagc ttgattattg ccatttcagc ctttcccttg gagcaggttt ctacaccaat
     2401 gataaatcta gctcaggttc aagaagcctt tgcccaaggg aataactatg aaatcacgca
     2461 tccagtcaag ggagatgata attactacat tatctttact tctggtacga ctggtaagcc
     2521 taagggagtg cagatttcac atgataatct cctcagcttt acaaactgga tgattacgga
     2581 taaggaattt gcgacaccga gtcgtccgca aatgctggca cagccacctt attcttttga
     2641 cttgtctgtc atgtattggg caccgacctt ggcacttggt ggtacgcttt tcactcttcc
     2701 ttcagtcatc actcaggact ttaagcaact ctttgcggct atcttttcat tgccaatcgc
     2761 tatctggaca tcaacaccat cctttgcaga tatggccatg ttgtctgaat acttcaacag
     2821 tgagaaaatg cctggaatca cgcatttcta ctttgatggt gaagaattga cggtcaaaac
     2881 agctcaaaaa ctgcgcgagc gtttcccaaa tgcccgtatc atcaatgctt acggcccaac
     2941 agaagcgaca gtagctctgt cagcagttgc cgtgacagac gagatgttag cgactctcaa
     3001 acgcctacca atcggctata ccaaggctga ttctccaacc tttatcattg acgaggaagg
     3061 aaataaactg ccaaatggtg agcagggaga aatcattgtt tctgggccag ctgtttcaaa
     3121 aggttatatg aacaatcctg aaaaaacagc agaagccttc tttgagtttg aagatctgcc
     3181 agcctatcac acaggcgatg tgggaaccat gacagatgag ggcttgcttc tctacggcgg
     3241 acgcatggac ttccagatta agtttaacgg ttaccgcatt gagttagaag atgtctctca
     3301 aaacctcaac aagtctcgct ttatcgaatc tgctgtcgca gtaccgcgct ataacaagga
     3361 ccacaaggta caaaatctat tggcttatgt catcttaaaa gacggtgttc gtgagcagtt
     3421 tgagcgagat atcgatatta ccaaggccat caaggaagac ctgacagaca tcatgatgtc
     3481 ctatatgatg ccatctaaat tcctttaccg agacagtttg ccactaactc caaatggaaa
     3541 gattgacatc aaaggattga ttaacgaggt gaataagaga tgatggagtt ttttcaacag
     3601 cttcctcatt tagagccata tggcaatcct cagtattttg tttatgtgat tgctgcaacc
     3661 ttgcccatct ttataggtct ctttttcaag aaacgctttg cctggtatga agtgttggta
     3721 agtctcttct ttattgtcac catgttggtg ggtggaaaga ccaatcaact agctgccttg
     3781 ggtatttacc tttgctggga aatattgctc ctgcttttct acaagcatta tcgaaaaagc
     3841 aaggatggca agtgggtctt ctacttagtt agttttctgt ccctacttcc gattatcttt
     3901 gtcaaggtgc aaccagctat caatggaacg cagtctttgc ttgggttctt gggaatttct
     3961 taccttacct ttcgttcggt tgggattgtc atcgagctga gagatggagt gattaaggat
     4021 tttaccctct gggaattcct ccgtttcctt ctcttcatgc caactttctc gagtggtcca
     4081 atcgatcgct ttaagcgatt taatgaaaat tatcaggcta ttcctgagcg agatgagttg
     4141 atggatatgc tggatgaatc tgtccgctat atcatgtggg gctttttgta taagtttatc
     4201 ctagctcatg ttttaggaga gaccttacta cctcctctga agaatttagc cttgcagtca
     4261 ggtggcttct ttaatctcta tgccttggca gttatgtata cttttggtct ggaactcttc
     4321 tttgactttg caggttattc tatgtttgct ttggccatct caaacttgat gggaatccgt
     4381 agccctatca actttaacaa gcccttttta tcaagggatt taaaggagtt ttggaatcgc
     4441 tggcatatga gtctgtcctt ctggttccgt gactttgtct ttatgcgaat ggtgatggtg
     4501 ttaaccagaa agaaagtctt taaaaatcgt aatgtaacct caagcatggc ctacattgta
     4561 aatatgctga ttatgggatt ttggcatggt gtgacctggt actatatcgc ctatggactc
     4621 tttcatggac taggcttggt catcaatgat gcctgggttc gcaagaaaaa aacgctcaat
     4681 aaggaacgga aaaaagcagg gaaggctgcc ctacctgaga atcgctggat tcagttgctt
     4741 ggcatggttg tcactttcca tgttgtcatg ttgtcattct taatcttttc tggattcttg
     4801 aataatctat ggtttaaaaa ataaaaggaa ataaaatatg gatatcaaat cagaagttat
     4861 tgaaattatt gatgagttgt ttatggaaga tgtttctgac atgatggatg aagatctttt
     4921 tgatgcaggt gtcttggata gtatgggaac ggttgagttg attgtggaga ttgagaaccg
     4981 ttttgacatt cgtgtccctg taacagagtt tggtcgtgac gactggaata cagctaataa
     5041 aatcatagct ggtattgtgg agctacaaaa tgcttaaacg cttatggatg atcttcggac
     5101 cggtcttgat cgctggtttg ttggtttttc tgctcatttt cttttatcct actgagatgc
     5161 atcataatct aggagctgaa aagcgttcag cagtggctac tactatcgat agttttaagg
     5221 agcgaagtca aaaagtcaga gcactatctg atccaaatgt gcgttttgtt cccttctttg
     5281 gctctagtga atggcttcgt tttgacggtg ctcatcctgc ggtattagct gagaaataca
     5341 atcgttccta ccgtccttat cttttaggac aggggggagc tgcatcgctt aaccaatatt
     5401 ttggaatgca acagatgtta ccacagctgg agaataaaca agttgtgtat gttatctcac
     5461 ctcagtggtt cagtaaaaat ggctatgatc cagcagcctt ccagcagtat tttaatggag
     5521 accagttgac tagttttctg aaacatcaat ctggggatca ggctagtcaa tatgcagcga
     5581 ctcgcttact gcaacagttc ccaaacgtag ctatgaagga cctggttcag aagttggcaa
     5641 gtaaagaaga attgtcgaca gcagacaatg aaatgattga attattggct cgttttaatg
     5701 aacgccaagc ttcctttttt ggtcagtttt cggttagagg ctatgttaac tacgataagc
     5761 atgtagctaa gtatttaaaa atcttgccag accagttttc ttatcaggca atagaagatg
     5821 ttgtcaaagc agatgctgaa aaaaatactt ccaataatga gatgggaatg gaaaattatt
     5881 tctataatga gcagatcaag aaggatttga agaaattaaa ggattctcag aaaagcttta
     5941 cctatctcaa gtcgccagag tataatgact tgcagttggt tttaacacag ttttctaaat
     6001 ctaaggtaaa cccgattttt atcattccac ctgttaataa aaaatggatg gactatgctg
     6061 gtctacgaga ggatatgtac caacaaacgg tgcagaagat tcgctaccag ttggaaagtc
     6121 aaggttttac caatatagca gatttttcta aggacggcgg ggagcctttc tttatgaagg
     6181 acaccattca ccttggttgg ttgggttggt tggcttttga caaggcagtt gatcctttcc
     6241 tatccaatcc cacaccagct ccgacttacc atctgaatga gcgctttttc agcaaagatt
     6301 gggcgactta tgatggagat gtcaaagaat ttcaatagat aatataatat agaagagttc
     6361 aagaatgaaa ctagttttca cgttttttct tgactctttt tttgcttgtg atataattaa
     6421 ctggtaaaca aaatgtcaaa gaatagtatt tttctcttaa aaaagagaag tctaaaagga
     6481 aaggagtcag atatgagaca gctagcaaag gatatcgatg cttttttgaa tgaggtgatt
     6541 ttgcaggcgg aaaatcagca tgaaatccta ataggtcatt gcactagcga ggtggccctg
     6601 accaatactc aggagcatat ccttatgctc ttgtcagagg aatctttaac aaattcagaa
     6661 ttggcccgtc gtctcaatgt cagtcaggcg gcagttacca aggccattaa gtctttggtc
     6721 aaggaaggga tgttggaaac atctaaagat tctaaagatg cgcgtgtgat tttttatcag
     6781 ttgactgact tggctcgtcc aatcgctgag gagcaccacc atcaccatga gcatacactt
     6841 ttaacctatg aacaagtggc gactcagttt actccaaatg aacaaaaagt gattcagcgg
     6901 tttttgactg ctttagtagg agaaatcaaa taatgagata tattacggta gaggatttgt
     6961 ccttctatta tgataaggag cctgttcttg aacatatcaa ttattgtgtt gatagtgggg
     7021 aatttgttac cttgactggg gaaaatggag cggctaagac gacgctcatc aaggctagtc
     7081 ttggaattct gcaaccacgc attggaaagg tggctatttc aaagacaaat acgcaaggta
     7141 agaaattgag aatagcctat cttcctcaac aaattgccag ttttaatgct ggttttccaa
     7201 gtacggtcta tgaatttgtc aagtcgggtc gctatccgag aaaaggctgg ttccgtcgtt
     7261 tgaatgctca tgatgaggag catatcaagg ctagtctgga ctcagttggc atgtgggaac
     7321 atcgagacaa acgcttgggg tctctatctg ggggacaaaa gcagcgagcg gtgattgcgc
     7381 gtatgtttgc ttctgaccct gatgtgttta tcctagacga gccgacaacg gggatggatg
     7441 caggaagtaa aaatgaattt tacgaactca tgcaccacag cgcccatcat catggcaagg
     7501 ctgttttgat gattacccat gaccctgaag aagttaagga ttatgcggat cgcaatattc
     7561 atctagtccg taaccaagac tcgccatggc gttgtttcaa tgttcatgag aatggccagg
     7621 aggtgggcca tgcttagttt attatcttac gactttatac aacgcgcctt tttggcggtt
     7681 attgctatga gtcttttctc accggtattg ggaaccttcc tcatcttgcg tcgtcagagt
     7741 ttgatgagtg atacccttag ccacgtctca ctttcaggtg tagcctttgg tctggttttg
     7801 gggatttctc caactgtttc tactattgcc attgtcttga ttgcggcggt ctttctggag
     7861 tatctccgta cggtttacaa gagctttatg gaaatcggga cagctatcct catgtcaaca
     7921 ggtctggctg tttctctgat tgtcatgagc aagggtaaaa gctcgagttc aatgagtttg
     7981 gaccaatatc tctttggttc gatcgtgact atcagtgaag aacaggtcat ttccctcttt
     8041 gtcattgcgg cggttgtttt gattttgacc tttctctttc ttcgtcctat gtatatctta
     8101 acttttgacg aagatacggc ctttgtggat ggcttgccag ttcgtaccat gtccattctt
     8161 tttaacatgg tgacaggggt ggctattgcc cttatgattc ctgcagcagg agctcttctg
     8221 gtatcgacca ttatggtctt gccagctagt attgccctgc gtctggggaa aaactttaaa
     8281 tcggttatgc tgcttgccag tgcgattggc tttttgggaa tggtagcagg actttacatt
     8341 tcctactatg cagaaacacc tgcaagtgca agtattacca ttatttttgt aactgtcttt
     8401 atactaatca gtttagtaag acgttttatc aaataggaga cgaacgtgaa aaaaattagc
     8461 ttattactag ccagtctatg tgccttgttt ttagtggctt gttccaatca aaaacaggca
     8521 gatggtaaac tcaatatcgt gacaaccttt taccctgtct atgaatttac caagcaagtc
     8581 gcaggagata cggctaatgt agaactccta atcggtgctg ggacagaacc tcatgaatac
     8641 gaaccatctg ccaaggcagt tgccaaaatc caagatgcag ataccttcgt ttatgaaaat
     8701 gaaaacatgg aaacatgggt acctaaattg ctagatacct tggataagaa aaaagtgaaa
     8761 accatcaagg cgacaggcga tatgttgctc ttgccaggtg gcaaggaaga agagggagac
     8821 catgaccatg gagaagaagg tcatcaccat gagtttgacc cccatgtttg gttatcacca
     8881 gttcgtgcca ttaaactagt agagcacatc cgcgacagct tgtcagcaga ttatcctgat
     8941 aaaaaagaga cctttgagaa gaatgcagct gcctatatcg aaaaattgca agccttggat
     9001 aaggcttacg cagaaggctt gtctcaagca aaacaaaaga gctttgtgac tcaacacgca
     9061 gcctttaact atcttgcctt ggactatgga ctcaaacaag tcgcaatctc aggactttct
     9121 ccagatgcag agccatcagc tgctcgcttg gcagaattga cagagtatgt caagaaaaat
     9181 aaaatcgcct atatctattt tgaagaaaat gcctcacaag cccttgctaa cacactttca
     9241 aaagaagcag gtgtcaaaac tgatgtcctc aatcctttag aaagtctgac agaagaggac
     9301 accaaggctg gagaaaacta catttccgtg atggagaaaa acctcaaggc tttgaaacaa
     9361 acaacagacc aagaaggccc agcaatcgaa cctgaaaagg cagaggatac caagacagtc
     9421 caaaatggtt acttcgagga tgcagctgtc aaggaccgca ccttgagtga ctatgcaggt
     9481 aactggcaat cagtttatcc tttccttgaa gacggcacgt ttgaccaagt ctttgactac
     9541 aaggctaagt tgactggtaa gatgacccag gctgagtaca aggcttacta tacaaaaggc
     9601 tatcagacag atgtgactaa gattaacatt actgataata ctatggaatt tgttcaaggt
     9661 ggacaaagca agaaatacac ttacaagtat gtcggtaaga aaattttgac ttacaagaaa
     9721 ggcaatcgtg gcgtgcgttt cctctttgaa gccacagatg ctgacgctgg acaattcaag
     9781 tatgttcagt ttagtgacca caatgttgcc ccagttaagg cagaacattt ccatatcttc
     9841 tttggaggca caagccaaga agccctcttt gaagaaatgg acaactggcc aacctactac
     9901 ccagataacc tatctggcca agaaatcgcc caagaaatgt tggcgcattg atgagaaatc
     9961 gactagttca taagagctag tcggtttttt gatactagat ggctaacttc attatagacc
    10021 tttcagaact ttaaacaata aataaaactc ttgaaatatc tgggcttata tgctagaatg
    10081 tagttagtgt ataaggttca ttagaacacc aaagccccta actagtgcca tagttaaggg
    10141 cttttttgac gtatcttagc gatttaacgg gtgtttatag gctagtcagt cggtctactt
    10201 cttaccatct agccatttgc agacgaaata caagataatt ccagctataa catctgctat
    10261 aatagtaaga gcaagctctg gtataaggct cattagtttc acctcctctc acgaacccat
    10321 aggaacgtaa tcggtaaccg atgacaaaag tattatatca cactaaattt agatcatcaa
    10381 cctcacttaa tgcttgaact attgtagatt atatgctaaa atgtagttaa ttgataaggt
    10441 tcattagaac accaaagccc ctaactatgg ccgtagttaa gggctttttt gacgtatctt
    10501 agcgatttaa cgggtgttta taggctagtc actcggtcta cttcttacta tctagccatc
    10561 tgcagacgaa atacaagata attccagcta taacatccgc tataatagta agagcgagct
    10621 ctat
//
LOCUS       DAVBOM010000067        10492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBOM010000067 DAVBOM010000000
VERSION     DAVBOM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.067"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(26..628)
                     /locus_tag="VQ878_001885"
                     /pseudo
     CDS             complement(26..628)
                     /locus_tag="VQ878_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(1214..1990)
                     /locus_tag="VQ878_001886"
     CDS             complement(1214..1990)
                     /locus_tag="VQ878_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET3096183.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            2112..2858
                     /locus_tag="VQ878_001887"
     CDS             2112..2858
                     /locus_tag="VQ878_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3096184.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2871..3851
                     /locus_tag="VQ878_001888"
     CDS             2871..3851
                     /locus_tag="VQ878_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET3096185.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGI
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            4046..4366
                     /locus_tag="VQ878_001889"
     CDS             4046..4366
                     /locus_tag="VQ878_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3096186.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4412..4720
                     /locus_tag="VQ878_001890"
     CDS             4412..4720
                     /locus_tag="VQ878_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3096187.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4737..6035
                     /locus_tag="VQ878_001891"
     CDS             4737..6035
                     /locus_tag="VQ878_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3096188.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            6186..8624
                     /locus_tag="VQ878_001892"
     CDS             6186..8624
                     /locus_tag="VQ878_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET3096189.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8643..9311
                     /locus_tag="VQ878_001893"
     CDS             8643..9311
                     /locus_tag="VQ878_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET3096190.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9329..10417
                     /locus_tag="VQ878_001894"
     CDS             9329..10417
                     /locus_tag="VQ878_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET3096191.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         3438 a         1487 c         2086 g         3481 t
ORIGIN      
        1 aatttgtcct gttcttattt cattttacta taccatcaat aagtgtgaaa agatctttta
       61 cataagacca agccttatta tctttgtaac caccttgagc ttgtagcata tttgttaatt
      121 gagcaaaggc gctagaagag tttgctgggt cagcagttgc gatttttcct tttagttcag
      181 gtttgagaag gtcgctatat ccttcgatgt tcatgccttt agttaaatca gggtggacga
      241 ttaaaacact accatctagt gtataaggag tagagaagcc agttgtgttt tgatattctt
      301 tgataacatt atcattttct tttgaaatat agttttcaaa gagttctccg tgggtagcat
      361 attgtgtata agaaccacca aagataacat cagctacagg aacttctttt tctgactcta
      421 gttttttgaa aagttctcca gtaccagctt gaatcagttc tattttgata ccatattttt
      481 cttcaaaggc aggaatagtt gctccaatta agccttctga gtttggtgaa taaacgacta
      541 gcgaaccacc gtctccttta tcagatgaac tgtcatcggc agattcatta gaagaacaag
      601 cagcataata catccatttc tttttcatga tggatacctc cgttgtgtta tttaagttta
      661 ttttaaaaca atgtaagcgt ttttaaaacc tacaattcta ttctatagtg tattgaatct
      721 ataacagtac accttgactg ctaaaatatt tctataaatt aatttgactt tcctgataga
      781 gatgttcaca tcttatttca attcactata ttagagtaaa attctctaca aaaaaaagaa
      841 tagcctattt tactattttt ccgagtgatt tcaattcctt tggggaaata tggagatact
      901 ttttaaatcc tgacaaatgg ttgtttcttt ttctaaatcg gtgatactgt atcggagaat
      961 gcgcgtgagg tcacaaaggc tgcgatagag cttctatgga gaatttcttt ttggagagat
     1021 tttttaaagg aatgagacat ccgctacctc cttggaaggt tttttgtgat aagtatagca
     1081 gtttaaaaat tctagagcaa ggtaaaatag aaaaggtttg gctaaaattt tttagctaaa
     1141 ccttttgaaa agttaagtat gtattataga tgcttgttat ctgcaaatat ctagagcatt
     1201 tcaaggaaat aaactagaaa taacaattaa tatggtggtt cagaaatacc ttttgataat
     1261 caataagatc ttcaggatga agtgcgttga ctccatccat ttcatatttc cgatttaata
     1321 aacgatattt gttttcacca aattgatgaa aagggagtag ttgaacttgg tcgatattta
     1381 atgagttaaa tagagtagcg aatttttctg catcctctaa actattgtta aaattaggaa
     1441 taactgggat tcttaaaacg atagttttat tttgagaaaa agcataatga atgtttttaa
     1501 taatcatttg attaaaaacc ccagtcactt ttttatgttt tatagaatta taatgtttta
     1561 ggtctgtgta gataaaatcc acatattgaa ttaaatcgat aaatttttca tgatcaacaa
     1621 aggcagtagt ttcaatggca gtgtgtatgt gatgttcttt agctgatttt aagatggctt
     1681 tagcaaattc aaactgagca aatatttcac ctcctgataa agttaaacct ccaccggatt
     1741 cttcgtaaaa ttctttgtct tttaatacct ctgtaataat ttcttctaca gtcttttctt
     1801 caccgactaa ggtgaatttc tctcgttgag catctttcat tttttcaggt ttcattcttt
     1861 gagattcagg attagaacac catggacagc gcagaggaca tccttttaaa aaaacagttg
     1921 tacgaatacc cgggccgtca tgaattgaaa agtgttgaat attaaaaata attcctttag
     1981 atatttccat aagagttcct cctcttcata agtctatcct atcacaaaaa cgaaagaaaa
     2041 acaattacga acgaaaggtt aatttgttgt tttttgcttt ttattttggt agaataaaac
     2101 ggaggtgtaa aatgaaaaga ttggaacaaa ttattaaatt agtatcagaa tatgaaaaga
     2161 tcgacgttaa tacattatcg gaaaaattaa atgtatcgaa agtaacgatt agaaaagatt
     2221 tagataaatt agagtcaaaa ggtttattac acagagagca tggatatgct gtattaaata
     2281 gtggagatga cttaaatgta cgtttgtcaa ttaattatga aattaagaga aaaattgttc
     2341 aggaagcagt aaaattggtg tcagataatg aaacaataat gatagaatct ggatcgacct
     2401 gtgctttact tgctgaggaa atttgcaagc aaaaaagaaa tgttacgatt gtaacaaatt
     2461 cattttttat agcaaatttt gtgagagctt atgattcatg tcgtattatt gttcttggtg
     2521 gagagtttca gaaggattca caggttactg tgggaccttt attaaaagaa atgatacaga
     2581 cttttcatgt gcgtcaagct tttgttggga cagatggcta cgataaagag atgggcttta
     2641 caggaaaaga tttaatgcgc agtgaggtag ttcaatatat ttcagcagcg tcggataaag
     2701 tcattgtact aactgactca agtaaatttg ataaaagggg tacagtaaga agatttgctt
     2761 taagtcaagt ctatgaagta ataacagacg aaaaactttc taaacaaaat atagctacat
     2821 tagaaaatgc tgggataatg gttaaggtag tttcgtaaga ggttaagtgt atgaatcaag
     2881 ataggaataa actgctctct aaaattgctt atctgtatta tattgaaaac ttaaatcagt
     2941 cacaaatagc agcaaaatta ggaatttata gaacctctat tagtagaatg ttaacagaag
     3001 caaggaatgc aggaattgtt aaaattgaaa tagagaattt tgataccaat atgtttaagt
     3061 tggaaaatta tgtaaaagaa aaatatggtc tggaaagttt agaaattatt ccaaatgaat
     3121 ttgatgataa tccaacaatt ttatctgaaa gaatttctca agttgcagca ggtatcctta
     3181 ggaatctaat tgatgataat atgaaaattg gcttttcttg ggggaaaagt ttaagtaatt
     3241 tagtagattt aattcacagt aaaagtgtcc gaaatgttca cttctatcct ctagcaggtg
     3301 gtcctagtca catacacgct aaataccatg tgaatacact gatttatgaa atgtctagaa
     3361 aatttcatgg agagtgtaca tttatgaatg caacgattgt gcaagaaaat aaattgttag
     3421 cagatggtat tttgcaatca agatattttg aaaatttgaa aaatagttgg aaagatttag
     3481 atatagctgt agtcggaatt ggtgatttta gcaataaagg aaagcatcaa tggttagaca
     3541 tgcttacaga ggatgacttt aaagaattga ccaaagttaa aactgtagga gaaatttgtt
     3601 gtcgattttt tgattcaaaa ggtaaagaag tctatgaaaa cttacaggaa agaacgatag
     3661 caatctcttt ggaagattta aaaaatattc ctcaaagttt agctgttgct tacggtgata
     3721 cgaaagtatc ttcgattctt tctgtcttgc gtgctaattt agtaaatcat ttgattacag
     3781 acaaaaatac aattttaaaa gttttggaag aagatgggga tttgactttt agagagattc
     3841 taggtgagtg aaaatgatag actgattcag tttatcgttt ttctttttag ttgattgcac
     3901 atttgtgctt atataaacaa aaatagttta tctgttgttt ttggattgac aactttatta
     3961 tgtagttgta ttctatagtt acaaaagaaa attttaaaat ttcaaatgaa aaaagctttt
     4021 tacatagtga aatgaggagg aatttatgga aattattgtt ccagatcaaa ttatcatggg
     4081 tttaatttta tatgctggcg atgcgaaaca acatatttat aaagcattag attacataaa
     4141 gaacggtaca tgtgaacgat gtgaagaaga aatccagtta gctgatgccg ccttattaga
     4201 agctcataat ctacaaacaa aattcttggc acaggaagcg tctggtacaa agacagaaat
     4261 tacagctctc tttgttcatt cacaagatca tctcatgact agtatgacgg agattaattt
     4321 aatcaaagaa attattagtt tgagaaaaga acttcataaa aaataatact agagtattat
     4381 cattgttatt aacatagagg aggaaaacat aatggtgaag attggtttgt tttgtgcagc
     4441 aggtttttct actggtatgc ttgtaaataa tatgaaaatt gcagcgcaag ctagtggagt
     4501 tgaggcagaa atagaggcgt tttctcagtc taaattagcg gattatgcgc caaatataga
     4561 tgttgcacta ttgggtccac aagttgctta tacattagat aaatcaaaag aaatttgtga
     4621 taagtgtgat gttccgatag ctgttattcc gatgatggac tatggtatgt tagatgggaa
     4681 aaaagtatta gatttggccc tatctttgat tagtgggtaa gaaaaggaga tttattatgt
     4741 caaagatgga tgttcagaaa atcattgcac cgatgatgaa gtttgtgaat atgcgtggca
     4801 ttatagctct aaaagatggg atgttagcaa ttttgccatt gacagtagtt ggtagtttgt
     4861 tcttgattat gggacaattg ccgttcgaag gattaaataa gagcattgct agtgtttttg
     4921 gagctaattg gacagagccg tttatgcaag tatattcagg aacttttgct attatgggtc
     4981 taatttcttg tttttcaatt gcctattctt atgctaagaa tagcggagta gaggctttac
     5041 cagctggagt tctatctgta tctgcattct ttattttgct aagatcatct tatatcccta
     5101 aacaaggtga ggcgattggg gacgctatta gtaaagtttg gtttggaggc caaggaatta
     5161 tcggtgctat cattataggt ttggtagtag gaagtattta taccttcttt ataaagagaa
     5221 aaattgttat taagatgcca gaacaagttc cacaagctat tgccaaacag tttgaagcaa
     5281 tgattccagc atttgtaatt ttcttatctt ctatgattgt atatatttta gcgaagtcat
     5341 tgactaatgg cggaacattc atagaaatga tttattctgc tattcaagtt ccgttgcaag
     5401 gtttaactgg atctttgtat ggtgctattg gaattgcatt ctttatatca tttttgtggt
     5461 ggtttggtgt tcatgggcaa tcggtagtaa atggagtagt gacagctctg cttttatcta
     5521 atcttgacgc taataaagct atgttagcct ctgctaatct atcattagaa aatggtgcac
     5581 atattgttac tcaacaattt ttagattcat ttttaattct atcaggttca gggattacgt
     5641 ttggtcttgt agttgccatg ctttttgcag caaaatcaaa acaataccaa gccttaggaa
     5701 aagttgcagc ttttccagca atatttaacg taaatgagcc agttgtattt ggatttccga
     5761 ttgtcatgaa tccagttatg tttgtacctt tcattcttgt tcctgtactt gcagctgtga
     5821 tagtatatgg agctattgca acaggtttca tgcagccatt ctcaggggta acattgcctt
     5881 ggagtacacc agctattcta tcaggatttt tggtgggtgg atggcaaggt gttgtgactc
     5941 agttattagt attggtgata tctacagtgg tttactttcc attctttaag atacaagatc
     6001 gtttagctta ccaaaatgaa atcaaacaat cttagaggta tttgtgtgtt actgttaaac
     6061 tcacacattt gtgctaaaaa ttagagagtt aaaatttttc tagttaaaag cttgaaaatt
     6121 tctataaaaa tcggtattat attttcgaaa gaaataaaaa tattttcgaa agaaaggtgc
     6181 ttacgatggt aaatacagaa gtagcaagaa caacaatcaa gacagaatat tttggcagcc
     6241 ttactgaaag gatgaacaaa tatcgagaag atgttttaaa taaaaaacct tatattgatg
     6301 ctgagagagc agttctagca acacgcgcct atgaacgata caaggaacaa cctaatgtcc
     6361 taaaacgtgc atatatgctg aaagaaattt tggaaaatat gtctatctat attgaagaag
     6421 aatctatgat tgcgggaaat caagcttctt ccaataaaga tgctcctatt tttccggaat
     6481 atacgctaga atttgttctc aatgagttgg atctttttga aaagcgtgat ggagatgttt
     6541 tctatattac agaagaaaca aaagaacaac ttagaagtat tgctccgttt tgggaaaata
     6601 ataatttacg tgctagagct ggtgccttat tacctgaaga agtgtcagtt tatatggaaa
     6661 caggattctt cggtatggaa ggtaagatga attctggaga tgctcactta gcagttaact
     6721 atcagaaact tttgcaattt ggtttaagag gttttgaaga gcgggctcgt aaagcaaaag
     6781 tagctctaga tttaacagat ccagcaagta ttgataaata tcatttttac gactctatat
     6841 ttattgtaat cgatgctatt aaagtatatg caaagcgctt tgttgctctt gctaaaagtt
     6901 tagccgaaaa tgcaaatcct aaacgtaaga aagaattact tgagattgca gatatttgct
     6961 ctagagtccc atatgaaccg gcaactactt ttgcagaagc tattcaatca gtttggttta
     7021 ttcaatgtat tttacaaatt gaatctaatg gccactctct ttcatatggc cgttttgatc
     7081 aatatatgta tccatatatg aaggctgatt tagaaagtgg taaagaaaca gaagatagca
     7141 ttgttgaacg tctgacaaat ctttggatta agacaattac aattaataag gttcgcagtc
     7201 aatcacatac attttcttca gcaggaagtc ctttatatca aaatgttaca attggtggac
     7261 agactcgaga taagaaggat gctgttaacc cattatctta tttggtatta aaatcagttg
     7321 cacaaaccca tctaccgcaa cctaatctaa ctgtacgtta ccatgcaggt ttagatgctc
     7381 gtttcatgaa tgagtgtatt gaagtgatga aacttggttt tggtatgcct gcatttaata
     7441 atgatgagat tattattcct tcttttattg caaaaggagt attggaagat gatgcttatg
     7501 attacagtgc cattggatgt gttgaaacgg cagttccagg gaaatggggc tatcgttgca
     7561 caggtatgag ttatatgaac ttccctaagg ttctacttat cacgatgaat gatggaattg
     7621 atccggcttc gggtaaacgg tttgcaccaa gctttggtca ttttaaggat atgaagaact
     7681 tttctgaatt agaaaatgct tgggataaaa cactaagata tttgacacga atgagtgtta
     7741 ttgttgaaaa ttctattgat ttatcattgg aacgagaagt tcctgatatt ctatgttcag
     7801 cattgactga tgattgtatt ggtcgtggaa aacaccttaa agaaggtgga gcagtatatg
     7861 attatatatc aggattgcaa gttggaattg caaatttgtc ggattcatta gctgcaatta
     7921 aaaaattggt gtttgaggaa gaacgtataa gcccaagtca gctttggcat gcactggaaa
     7981 cagattatgc cggagaagaa ggtaaggtca ttcaagaaat gttgattcat gatgcaccta
     8041 agtatggtaa tgatgatgat tatgctgaca aattggttac tgctgcttat gacatttatg
     8101 ttgatgaaat tgctaaatat cctaatacac gttatggaag agggcctatt ggaggaattc
     8161 gttattcagg aacatcttct atatcagcca acgtagggca gggacgtgga acattagcaa
     8221 ctccagatgg acgcaacgcg ggtacaccgt tagcagaggg ttgttcacca tcacataata
     8281 tggatcaaca cggccctaca tctgttttaa aatctgtttc aaaattacca acagatgaaa
     8341 tcgtaggtgg ggttctctta aatcagaaag taaatcctca aacgttagcc aaagaagaag
     8401 ataaattaaa actaattgct ttgttacgaa cattctttaa tcgtttacat gggtaccata
     8461 ttcaatacaa tgttgtttcc agagagacgt tgattgacgc tcagaaacat cctgaaaaac
     8521 acagagactt aattgttcgt gttgcaggat actctgcatt cttcaatgtt ctttctaagg
     8581 caacccaaga tgacattata ggacgtactg agcatacttt gtaaaataaa gaggttcttt
     8641 ttatggaatt tatgcttgac acattaaatt tagatgagat taaaaagtgg tctgaaattt
     8701 tgccgctagc tggggtaact tcaaatccca ctattgcaaa aagagagggt tctattaatt
     8761 tttttgaacg aatcaaagat gtaagagaat tgattggctc cacaccctct attcatgttc
     8821 aggtgatttc tcaagatttt gaaggcatct taaaggatgc tcatgaaatt cgaagacaag
     8881 caggagatga tatatttatc aaagtacctg ttactccagc tggattacgt gcaataaagg
     8941 tgctaaaaaa agagggctac catatcactg caacagctat ttatacagtt attcagggat
     9001 tattagctat cgaagtagga gcggattacc tagctccata ttataataga atggaaaatc
     9061 tgaacattga ttcaaattct gtcattcgtc aattagctct tgctattgat agacagaact
     9121 ctcctagtaa gattttagct gcatccttta aaaatgtagc acaagtaaat aatgctttag
     9181 ctgcaggtgc gcatgctgtt acagcaggag cagatgtttt tgaatcagct ttcgccatgc
     9241 catctatcca aaaggcggtt gatgattttt ctgacgattg gtttgttact caaaatagtc
     9301 gttccattta gatagagagg aaatacatat gagaattttt gctagtcctt ctagatatat
     9361 tcagggggaa aatgccttgt ttgaaaatgc caaatcaatt ttggatttgg gaaattaccc
     9421 gattctatta tgcgatcagt tggtttatga tattgttgga aaacgatttg aagattatct
     9481 acataggtat ggtttccata ttgttctggc gctatttaat ggtgaagctt ctgacaatga
     9541 aatcaatcga gttgttgcct tggctgagaa agaaaattgt gatagtatta tcggtcttgg
     9601 tgggggaaag acgattgata gcgcaaaagc tattgcagat ttgattgaaa agcctgttat
     9661 tattgctcca acaattgcat cgaccgacgc acctgtatct gctttatctg ttatttatac
     9721 agatgaaggt gcatttgatc attatctatt ttattctaaa aatccagatt tagttttggt
     9781 tgatacaaaa gttatttcac aagcccctaa gcgtttatta gcgtctggta ttgcagatgg
     9841 tttagcaact tgggttgagg cgcgtgcggt tatgcaggca aatggaaaaa ctatgttggg
     9901 acaacagcaa acattggctg gagttgcaat tgcgaagaaa tgtgaagaaa cgctgtttgc
     9961 agatggttta caggctatgg cagcttgtga agctaaagtg gtgacaccag cattagaaaa
    10021 tattgttgaa gctaatactt tattgagtgg tctaggtttt gaaagtggag gattagctgc
    10081 ggcgcatgca attcataatg gttttactgc attgacaggt gacattcatc atttaacaca
    10141 tggtgaaaaa gtagcttatg gaactttagt acaactatta ttggaaaata gacctaaaga
    10201 agaacttgat aagtatattg agttttacaa aaaaattggt atgccaacaa ctctaaaaga
    10261 aatgcatttg gatcaagttg gatatgatga tttaataaaa gttggtaaac aagcaactat
    10321 ggagggtgag acaattcatc agatgccgtt taagatttcg ccctcagatg ttgctcaagc
    10381 tattatcgct gtagatgcct atgtaaattc aaaataaaca ataaggacta ctgttttcca
    10441 aatggtagtc ttttattgat ccctgtattg aattctatag cagattgaaa ta
//
LOCUS       DAVBOM010000068        10489 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBOM010000068 DAVBOM010000000
VERSION     DAVBOM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.068"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            154..366
                     /locus_tag="VQ878_001895"
                     /pseudo
     CDS             154..366
                     /locus_tag="VQ878_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            266..712
                     /locus_tag="VQ878_001896"
     CDS             266..712
                     /locus_tag="VQ878_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3096192.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(850..2154)
                     /gene="eno"
                     /locus_tag="VQ878_001897"
     CDS             complement(850..2154)
                     /gene="eno"
                     /locus_tag="VQ878_001897"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET3096193.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2318..2764
                     /locus_tag="VQ878_001898"
     CDS             2318..2764
                     /locus_tag="VQ878_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET3096194.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPLGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2761..3876)
                     /locus_tag="VQ878_001899"
     CDS             complement(2761..3876)
                     /locus_tag="VQ878_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET3096195.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3990..4214)
                     /locus_tag="VQ878_001900"
     CDS             complement(3990..4214)
                     /locus_tag="VQ878_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3096196.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4159..4530)
                     /locus_tag="VQ878_001901"
     CDS             complement(4159..4530)
                     /locus_tag="VQ878_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET3096197.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4589..6022)
                     /gene="glgA"
                     /locus_tag="VQ878_001902"
     CDS             complement(4589..6022)
                     /gene="glgA"
                     /locus_tag="VQ878_001902"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET3096198.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6019..7158)
                     /gene="glgD"
                     /locus_tag="VQ878_001903"
     CDS             complement(6019..7158)
                     /gene="glgD"
                     /locus_tag="VQ878_001903"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET3096199.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7148..8290)
                     /locus_tag="VQ878_001904"
     CDS             complement(7148..8290)
                     /locus_tag="VQ878_001904"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET3096200.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8280..10208)
                     /gene="glgB"
                     /locus_tag="VQ878_001905"
     CDS             complement(8280..10208)
                     /gene="glgB"
                     /locus_tag="VQ878_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET3096201.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGSLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3194 a         2299 c         1845 g         3151 t
ORIGIN      
        1 cttggtttca gaaatttctc ttaccaacat taaccgcacc attggttatt atattaaaac
       61 gaagtaagaa taggacaaat cgatcaggac agtaaaatct aattctaaca atgttttaga
      121 agtagaggtg tactattcta gtttcaatct actatattaa tggacaatgc aagattccat
      181 agaatgggga agctagaact cttgtgtgaa gagtttgggc ataaactttt acctcttcct
      241 ccctactcgc ctgagtacaa tcttattgag aaaacatggg ctcatatcaa aaagcacctc
      301 aaaagggtat taccaagttg caataccttt tatgaggctc ttttgtcttg ttcttgtttc
      361 aattgactat ataaattgtc taagcgaaac aaccgataag aattggcaca aaagcgaccg
      421 tatttttgtt accaatacag gaaaaccagt tcatagttct atcttgagca agtctctcca
      481 gcgagcaaac gaacgcctta aaaaaccaat tcccaaacat ctgtcccctc acatcttcag
      541 acacaccact attagcatct tatcagaaaa taaaattcct ttaaaaacaa tcacggacag
      601 ggttggtcat tccgactctg aagtcactac ttccatctac acccacgtca caaagaacat
      661 gaaagatgaa gcaatcaatg tactggataa agttatgaaa aagatttttt aaaaagtttt
      721 gtcccttttt tgtcctctaa atacaaaaat agcccttcgg ataaaatccg aggggctaga
      781 aacgttgtta aatcaacggc cgaacttttg aatttcatgg ttcgggataa aatagttcac
      841 tgaactattt tattttttaa ggttgtagaa tgatttcaat ccacgatatt cagctacttc
      901 accaagttgg tcttcgatac gaagcaattg gttgtattta gcgatgcggt ctgtacgtga
      961 aagtgaacca gtcttgattt gtcctgcgtt agttgcaact gcaatatcag cgattgttga
     1021 atcttcagtt tcacctgaac ggtgtgatac aacagcagtg taaccagctt ctttagccat
     1081 ttcgatagct tcaaaagttt cagtaagagt accgatttgg ttaactttga taaggattga
     1141 gttagcagca ccttcttgga taccacgtgc aaggtagtca gtgtttgtta cgaagaagtc
     1201 gtcaccaaca agttgtactt tcttaccaag acgttcagta agagctttcc aaccatccca
     1261 gtcgttttca tccataccat cttcaatagt gatgattggg tatttgttaa ccaattcttc
     1321 aaggtagtcg atttgttctg cagatgtacg aacagcagca ccttcacctt caaatttagt
     1381 gtagtcgtaa actttacgtt ctttatcgta gaattctgat gaagcacagt caaatccgat
     1441 aaatacgtct ttacctggta catatccagc agcttcaatc gcagcaagga tagtttcaac
     1501 accatcttca gttccttcga aacgaggagc gaatccacct tcgtcaccta cggcagtttc
     1561 caaaccacgt gatttaagga ttttcttaag agcgtggaag atttcagcac cgtaacgaag
     1621 ggcttcttta aatgttggcg caccaactgg caagatcatg aactcttgga aagcgattgg
     1681 agcgtcagag tgagaaccac cgttgatgat gttcatcatt ggagttggaa gaactttagt
     1741 gttgaatcca ccaaggtagc tgtaaagtgg gatttcaagg tagtcagcag cagcacgagc
     1801 tacagcgata gacacaccga ggattgcatt cgcacccaat ttacctttgt taggagtacc
     1861 gtcaagtgcg atcatagcac ggtcaatagc ttgttgatca cgtacatcgt agccaatgat
     1921 agcttcagca atgatgttgt ttacgttgtc aacagctttt tgtgtaccaa gaccaccgta
     1981 acgagatttg tcaccgtcgc gaagttcaac tgcttcgtgt tcaccagtag aagctcctga
     2041 tggaaccata ccacgtccga aagcacctga ttcagtgtaa acttctactt caagtgttgg
     2101 gttaccgcgt gagtctagga cttcgcgagc gtaaacatca gtaataattg acatttttta
     2161 ctctccttat gagttaaatt ttttacacct ctataatacc ttaaaacccc tcctttttca
     2221 agaaaaaacg ttatctttgt gcaacttttc cttaacttta taaagtaatc gctttctttt
     2281 gtctgtttta ttctaacttt tatgatatac tgttttcatg acagatttat caaaacaatt
     2341 acttgaaaaa gctcatggtg ggttaaaaat aaatccggat gagcaaagac gctatcttgg
     2401 tacttttgag gaaagagttc ttggatatgt agatattgac acagcaaata gccctcagtt
     2461 agaaaaaggc tttttattta ttttagaaaa ccttcaggaa aaagcagagc cactatttgt
     2521 gaagatttca ccaactatcg aatttgataa gcaagttttc tacttaaaag aagcaaaaga
     2581 aactgatagt caagccacca tagtatctga agagcatatt acttctcctt tgggcctggt
     2641 tattcatagc aatgcaccag ttcaagtaga agaaaaagac cttcgacttg cttttccaaa
     2701 actttgggaa gttaaaaagg aagaaccagc caaaacatcc ttatggaaga aatggtttag
     2761 ctaaatcttg cacatattta ataagtgccc aatattggca gccgtgcgct ccagatagag
     2821 actggcattt ttcaaactat cttctaaagg ttcacttttc tccaaaatag aaaagacagc
     2881 ttggatattt tcaaatggta ggggaggtaa atcttcagca agactaccgc aaatagcaat
     2941 aacaggaact ccaacagggg ttctttttgc aacacctata ggcgctttcc cagcaaagct
     3001 ttgactatca agtcttcctt ctccaacaac aaccaagtca gcatctgaaa ctttcttatc
     3061 aaagttgatt aagtccaagc aggtatcaat tccagacacg atacttgcct gagcaaaggc
     3121 acacaaacca ccagcaaggc ctccacctgc tcctgctcct ttaatttcta atgttgcagg
     3181 tgagaatttt tcataaaaat cttggatcgc ctgatctacg actgcaaaca tagtcggatg
     3241 tagacctttt tgattgccaa aagtgtaagt cgcaccttga tgaccacata agggactcac
     3301 gacatctgct agaatatgaa tttgaacacc ttcaggaatt ttatagcaat tttctgttga
     3361 aacagaagct aagtttaata aggattgatc ggaagcaggc aagacatttc catccctatc
     3421 ataaaattga taacctaaac cagcagcaat ccccagtcct ccatcattac tggccgtgcc
     3481 accaacaccg atataaatat ctttaatccc tttagaaatg agatggagaa tcaactctcc
     3541 aataccacaa gtttggattt gaagtggatt tcgtttctct agcggaattt ttccaagacc
     3601 aaccaagtca gctacttcaa atagtgccag ttcccctttt tgaaaatagc gcatggcttc
     3661 tttttgtcca gaagggtctg tcacttggat ccatttttct tttaggtcaa gagaatgtcg
     3721 gatagcatct acagtacctt ctcccccatc accaacaggg cagaggagac attctacatc
     3781 tgctatcgat tgttggaagc ctctttttat tgcttcagct acctgttgag ctgtcaagct
     3841 ttccttaaac gaatccggtg caattacaat cttcatattt tccctcattc taaacagtca
     3901 atcaaaggaa gaacttctaa aaaatccctc ttgtcaacat gatgtggtat ttcttttttg
     3961 agcatttctt tggaacaaaa ggcgattcct cactccgccg acttcaacat taatagatta
     4021 ttgaccccat caccgattgc caccgttctt tctttagaaa gttttagttt ctttctccat
     4081 ttttccagag tttctttttt gacctgggga cttataattt gtccaactaa ttttcctgtt
     4141 aaaagacctt ctttgacttc aagctggttg gcagtgaaat aggcaatacc aagggatttt
     4201 gctaatctct ccaactattg gtgtaaatcc accagacacc agaccaacta ggatgccatt
     4261 cttttggaga atagagatga actctgggac atttagcgat agatgaattg agttgaagac
     4321 gttatcaaag accaaaatag gaagaccttc caacaaggac actctttttc ttaaactgct
     4381 ttcaaagacc aactctcctc gcattgctcg acttgtaatc tgcgaaattt ccgcctcatg
     4441 acctgcctct ctccctaaaa gatcaatcac ttcttctagg attaaggttc catctacatc
     4501 caaaacacac aagcctttta cttgagacat cagttctcct ctctaaacag cctaaaaatc
     4561 gtatgaagtc atcatacgat tttatctatt aattaactaa actatggtac aagtcaaggt
     4621 atgacttgca ggctgtatcc catgagaagt cactctccat agcttgtttt tgtaggtttc
     4681 tccaaatgtc tggatggttt ctatacaagt ccaatgctgt ttggaaagtc caatttaacc
     4741 aataaggaga tagattgtca aagctaaagc cagtaccgct tccttcgatt ggattgaaag
     4801 cgcgaactgt atctcgcaag cctccaactt catggaccaa tggcaaggtt ccataacgca
     4861 tagccatcat ttgagacaag ccacacggtt caaaacgact tggcatgagg aagaggtcac
     4921 aagcagcgta gatttcctga gcaagtttga catcaaaagt gatatttgtt gatagcttgt
     4981 ctgggtaaat ctgagcaaac catgagaaag ctccttcaaa ggctggatcg ccagttccca
     5041 aaagaacaat ctgaacatct tcttgcaaga tatggtgaag actttcgacc accacatcaa
     5101 aacctttttg acgtgtcaaa cgagaaacaa ttcccaccag tggaacgtct gctctaacag
     5161 gcaagccaac tctttcttgc aattttgcct tatttttggc tttcccagac aaatcttcct
     5221 gattgaaatg atagtctaaa agagcatccg tctgaggatt ataaagatca gcatcaatcc
     5281 cattcacgat accagatact ttaccagact ccattttaag aatctgatcc aaattacatc
     5341 caaactgact agtcataatt tcatgagcat agctaggtga aacagttgaa acacggttcg
     5401 catagagaat acctgccttc atccagttca gacagttgtt ccatcgaagg gtgccatcag
     5461 cgtaacgttc aaagccaact ccaaacaaat cacccaacat tccttctgaa aattgtcctt
     5521 ggaattctaa attatgaatg gttaaaactg tttcaatgtc ctcataggct tgaatccaac
     5581 ggtatttttc cttcaacaag aaaggaatca tagctgtatg gtagtcatga acatggagaa
     5641 gatcaggaat aaagtcaatc ctttccatag cctcaatggc agccagttgg aaaaaggcaa
     5701 agcgttctcc gtcatcaaaa tcaccgtaaa catgaccacg gaagaaataa tattgattgt
     5761 caataaagta gaaggttaca ccatttaata ctgttttctt aattccacaa tactgtctgc
     5821 gccaaccaac gctcacctca aaatgaagca catcttcaat ctgacttcca aatttagcct
     5881 ctaccatatc atagtagggt aaaatcactg caacttcgtg cccagctttt accagtgatt
     5941 ttggaagagc gccaatgacg tctcccaaac cacctgtttt tgaaaagggt gcaccctctg
     6001 ctgctacaaa taaaattttc atgaatgaat atcctctgtt actttagcac ctttcttaac
     6061 cacaactgga tgttctgcag ttcctcgaat cacaacacca ggctcaactt caaccccttt
     6121 gtccaagata gcatattcga cctgagcccc ttctccaata acaacacgag ggaagagcag
     6181 gctatcttta accaagctat ccttatggac atgaatatta cgtgatagaa cagaattagc
     6241 tacttgacct tcaataatac taccagaggc aaactgagaa gtgcttacct tagatgtatt
     6301 agcatagtaa gttggctctt cgtttttgac ctttgtataa atcttttggt ttggtgagaa
     6361 aagagaatag aatttttgtg attcaagcat atcgatattc gcttgataat aagatttaac
     6421 agagtgaata ttggctagat agcccgtgta ctcgtaggcg aaagctccct cttttacagc
     6481 caaatcccgt aaaacatagc gcaatttctc tggatgttct tttttagctt cttcttccaa
     6541 gtgttcaatc aaccaaggtg tatcaacgac aaagatatct gtagacatat tgaacgtttc
     6601 agctgttgac ttgctatcaa agagtttatg agaaagaaca tggtctgttt catctacatc
     6661 caagattgca tttacttctg aaatatcttt cttagctagt tttttataaa ctacagtgat
     6721 aggctctttt gttgtactat gtaggtggaa aacttggttc aaatcaatgt taataagaac
     6781 atcgcagttg agggcaaccg tttggtttga gccagaacgt ttcaaataag taagaagctg
     6841 ttggtagtat tcttttccaa ctgtactact ttctacacgg gtattgtaaa ttcctagata
     6901 gtaatggcta agaagggttg ataagcccca ctcgcgtcct gaacgaatat ggtcaaatac
     6961 tgagctgata ttatcctgct ggaaaatacc aaagacacta cgaacacctg cattagcaag
     7021 gcttgaaagt gggaagtcaa tcaaacgata tttcccacca aatggcaaac ttgctactgg
     7081 acggtggtcc gtcaatgtcg acatattgtg aaaaccaact gtatttccta aaatggcaga
     7141 atatttatca atcttcatct gttgctaccc ccactacttc attatatcct acaacttgta
     7201 cttcatctgt tccatcaatt tcgacaccgt cagaaataat cgcaccttca ccaataatgg
     7261 cacgtttaat cttagctcct tgaccaatga tagctccact catgataact gaatcaagga
     7321 cttccgctcc ttcgcgaact tgcgcgcctg ttgaaaggat agaatgttta acagttccat
     7381 caacgaaaca tccgtctaca actaatgagt cttccacatg agcatttgcc ccgaggaagt
     7441 ttggtggtga aatcaagttt cttgagtaaa tcttccattg acggttacga ctatccaagg
     7501 cattttctgg agaaatatac tccatgttcg cttcccaaag tgactcaata gtaccaacat
     7561 ctttccaata accactaaat tcataagcat aaacactttc acctgactca aggtaatttg
     7621 gaatgacatt tttaccaaag tctgacatgc caaccttgct cttttcagca gcgactaaca
     7681 tattacgaag gcgttgccaa tcaaaaatgt agattcccat agaagctttt gtagatttag
     7741 gttgagctgg tttttcttca aattcaacaa tacgattgtt agcatctgtg ttcatgatac
     7801 caaaacggct tgcttcttta agagggacgt ctaaaactgc tactgtcaag ctggcattat
     7861 tatccttatg agactggagc atatcatcat agtccatttt gtagatgtgg tccccagaca
     7921 aaatcaagac atactcagga ttgacactgt cgatatagtc gatattttgg taaatagcgt
     7981 gactagtccc ctcaaaccaa cgatttcctt cacttgcaga ataaggttga agaatagaga
     8041 cacctgaatt aataccgtct agtccccagc ttgaaccatt cccaatatgg ttgttgagag
     8101 caagtggttg atactgtgta acgaccccaa cattatgaat ccctgagttg gcacagtttg
     8161 atagggcaaa gtcaatgata cggtagcgcc caccaaattg cacagctggt tttgcgatgc
     8221 tttgagtgag tttaccgaga cgagttcctt gcccaccagc aagaatcaaa gctaacattt
     8281 catttttcat tttctactcc tttttggttt ttatttgtga cggttttagt agatttcaag
     8341 cgacgtttga ttttccatac acttgctccc atagccggta gagtaaaggt taaggtctgc
     8401 tcataatctt tccatagtcc ttcttgcgtt tgaacagttt gattatgttc tttccaaacg
     8461 cctccccact cttccaactc agtattccat acttcttcgt aaattcctgc aacgggtagt
     8521 ccgattgtaa aatctttccg ctcaacaggt accatattaa agatacagac taacatttct
     8581 ccctttttac ccttacgaat aaaggaaaga acactctggt ctcgattatc cgcatcaatg
     8641 atttcaatac catcatagct ggtatcaatt tcccacagac agcgatgatc tttgtaaaac
     8701 tggtttagct gagaagcgaa atacttcatc ttagcattca ttgggtcttc taggttagac
     8761 cattccaact gttcttcaga tttccattct aggaattgac cgtattcgct acccatgaag
     8821 agcaatttct taccagggtg acaaatttgg tacgtataga gattgcgcaa gcctgcgaat
     8881 tgattgtaac gatctcccca catcttatgc atcatactct tcttgccatg aaccacttca
     8941 tcgtgcgaga atggcaagag ataattctcc ttgaaaacat acataaagct gaaagtcacc
     9001 aggttaaagt catatttacg ataaatcgga tcttcttcgt agaaacggag gatatcattc
     9061 atccagccca tgttccattt gtagtcaaat cctagactac caatctcttt cattcccgta
     9121 atcttggtcg cagacgaact ttcttctgca atcatcatca catctggata ttctaactta
     9181 ataacttcat tcaagcgttg aagaaaataa taaccttcat agttgagatt tccgccatct
     9241 ttattaggtg tccatggagc attatcatag tccaaataga gcatgttgct aacagcatcc
     9301 acacgaatac catccaaatg atagacatca atccaatgct taatgcaaga aattaagaag
     9361 gactggactt cattttttcc aaggtcaaaa ttaagggcac cccaaccatg gttatgagcc
     9421 ttattatggt cttggtattc aaaagtcggt gtcccatcat aataggctaa ggcatcatcg
     9481 ttgatggtaa agtgacctgg tacccagtcc acaataaccc caatattatg ggtatgacac
     9541 tcctcgacaa aatcttgaaa ctcctctggt ctgccataag catgctctaa agcgaagtaa
     9601 cccataagct gataccccca actcaagccc aaaggatggg acatcaaggg cataaactca
     9661 atatgagtat agttcatttc aacgagataa ggaatgagtt catccttgag ctgggcaaaa
     9721 ctataaggac tgccatcaga atttcttttc catgatccag cgtgaacttc ataaatattg
     9781 acaggacgct cttcaaagcc ccaacgtttt cttcgtgcca gccaaagtcc atccttccat
     9841 ttcttctcag gaagctctgt taagattgcc cctgttcctg gacgagcctc atacctgaca
     9901 gcaaaagggt caatcttcat cagttgatga ccattttgac gtgtgacatg atatttgtaa
     9961 atatgccctt cttgagccat attggtaaag acttcccaga ccccaaaatc atttcttacc
    10021 attggaatct gattttcaat ccagttggta aaatcaccaa ccaagtgaac agcctgagca
    10081 ttaggtgccc aaacacggaa ggtatagcca tgctctccat ttagttcttc cctatgtgct
    10141 cctagataat gttggagata aaaattttca cccgtcataa aggtttttaa tgcttctcta
    10201 ttatccatat actccccttc tcctgtaagc gttttctatg tttttattat actacctttt
    10261 tagagaagat tcaagtaaat tactatactt ctttaattat tttgaaaatc tacaacaagt
    10321 tcacttactc gttcaattgt aaatcaatat tttttcaaaa aattgcgaaa acgcctttct
    10381 ttttctacta tagtgaaatg aaataaaaca tgcgcaagtc gattaaggaa tttaatctaa
    10441 tttctaacaa tgtcttagaa atcaaagtgt actattttaa cttcaatgt
//
LOCUS       DAVBOM010000069        10361 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBOM010000069 DAVBOM010000000
VERSION     DAVBOM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.070"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            95..343
                     /locus_tag="VQ878_001906"
     CDS             95..343
                     /locus_tag="VQ878_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096202.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            474..1646
                     /locus_tag="VQ878_001907"
     CDS             474..1646
                     /locus_tag="VQ878_001907"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET3096203.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1646..2920
                     /locus_tag="VQ878_001908"
     CDS             1646..2920
                     /locus_tag="VQ878_001908"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET3096204.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(2955..3920)
                     /locus_tag="VQ878_001909"
     CDS             complement(2955..3920)
                     /locus_tag="VQ878_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3096205.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     SYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(3901..5355)
                     /locus_tag="VQ878_001910"
     CDS             complement(3901..5355)
                     /locus_tag="VQ878_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3096206.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLIFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5731..7614
                     /locus_tag="VQ878_001911"
     CDS             5731..7614
                     /locus_tag="VQ878_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3096207.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            7763..8650
                     /locus_tag="VQ878_001912"
     CDS             7763..8650
                     /locus_tag="VQ878_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3096208.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(8693..9310)
                     /locus_tag="VQ878_001913"
     CDS             complement(8693..9310)
                     /locus_tag="VQ878_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET3096209.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(9725..9913)
                     /locus_tag="VQ878_001914"
                     /pseudo
     CDS             complement(9725..9913)
                     /locus_tag="VQ878_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3002 a         2028 c         2307 g         3024 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctactacttt ccttattgtc
       61 tgtaaatcta ctgaccttgt tgtttatccc agtcatggtt tctagttcgg gctcagagtt
      121 tcaaagtgga tggcaagagc atcaattgat tgctgagaag gttagtaaaa cacttgataa
      181 gacatttgat aaggatgtca gagaaattcc gaccagtcag ttttatcaaa aatttgtaga
      241 tgagatggga aggacttact caggaaattt gatcctccag gagctgataa ctgtgaatgg
      301 agcttataaa gctacttata tcggtgaact ctctagcaac taatcattct ttaaaatgat
      361 gaccaataag aggcttgatt tggtgaatca agtctttttt ctctctttta ctgccatttg
      421 tgataaaata gtatagaacg attttttaca tgaatgataa aacagaggta aatatgacaa
      481 tcggtattga taagattggt tttgcgacca gtcaatatgt cttgaaatta caagacttag
      541 cagaagcgag gggaattgac cctgaaaaat taagtaaagg actcttactc aaggaattga
      601 gtattgcgcc cctaactgag gacatcgtga ccttggcggc cagtgctagt gactctattt
      661 taactgagca agaaagacaa gaagttgaca tggtcattgt ggcgaccgag tcaggaattg
      721 accagagtaa ggctgcggcc gtctttgtgc atggcttgct gggcatccag ccctttgctc
      781 gtagtttcga gattaaagaa gcctgctatg gggcgactgc tgccctccat tatgccaaat
      841 tgcatgtgga aaattctccg gagtccaagg tcttggtcat tgcaagtgat attgccaaat
      901 acggtattga aactccggga gaacccactc agggtgccgg aagtgtggct atgttgatta
      961 cacaaaatcc acgcatgatg gcctttaata atgacaatgt agctcagacc cgtgacatca
     1021 tggatttctg gcgaccaaat tactcgacaa ctccttatgt aaatggtgtc tattctaccc
     1081 aacaatactt ggatagtttg aaaacgactt ggcttgaata tcaaaaacgc taccagctta
     1141 ctttggatga ttttgcggct gtttgtttcc acttgcctta tcctaaatta gcgctaaaag
     1201 gcttgaaaaa aatcatggat aagagcctgc ctcaagagaa aaaagacctc ttacaaaagc
     1261 attttgacca gtctattctc tacagtcaaa aggtggggaa tatctacaca ggttcacttt
     1321 tccttggact tttgtctctc ttggaaaata cagatagctt gaaagctggg gataaaatcg
     1381 ccctttatag ttacggaagt ggagctgtgg ctgagttctt cagtggtgaa ttggttgaag
     1441 gatatgaagc ttatttggat aaagaccgct tgaacaagct caaccaacga actgtcttat
     1501 ccgttgcaga ctatgaaaag gtcttttttg aggaagtaaa cttggatgaa acaaactctg
     1561 cccagtttgc tggctatgaa aatcaagatt ttgccttggt tgaaattctc gaccaccaac
     1621 gccgttatag caaggttgaa aaataatgaa gataagttgg aatggatttt ctaaaaaatc
     1681 ataccaagag cgcctcgagc tgttaaaagc tcaggcgctc cttagtcctg agagacaagc
     1741 tagtctggag aaggatgaac agatgagcgt gactgtggca gaccagctga gtgagaatgt
     1801 agtgggaact ttttctctgc cttattcact ggttccggag gtacttgtca acggtcagga
     1861 atacaccgtt ccctatgtga cagaagaacc ctctgtggtt gcggcggcca gctatgccag
     1921 caaaatcatc aagcgtgcag gtggttttac tgcacaagtc catcagcgac agatgattgg
     1981 gcaggtagcc ctttatcaag ttgctaatcc taaactagcg caagagaaga ttgccagcaa
     2041 gaaagcggag ctcttggagc ttgccaatca agcctatcct tctatcgtta aacgtggagg
     2101 tggggcgcgt gatctgcatg tcgagcagat aaaaggcgaa ccagactttc tcgttgttta
     2161 tattcatgtc gatacccagg aagccatggg tgccaatatg ctcaacacca tgctggaagc
     2221 cttgaaacca gtcttagaag aactcagtca gggacagagt ctcatgggaa tcctgtccaa
     2281 ctacgcgacc gattctctgg tgactgcaag ctgtcgcatc gcctttcgct acttgagccg
     2341 ccaaaaggat caaggacgag agattgcgga gaaaattgcg ttggctagtc agtttgcgca
     2401 ggctgatcct taccgagctg ctactcataa taaaggaatt tttaatggta ttgatgcgat
     2461 tttgattgcc actggtaatg actggcgtgc catcgaagct ggggcccatg cctttgccag
     2521 tcgagatgga cgctatcaag gtcttagttg ctggacgctg gaccttgaaa gagaagaatt
     2581 ggtcggtgag atgaccctgc ccatgcctgt agcgactaag ggtggctcta tcggcctcaa
     2641 cccacgtgta gctctcagtc atgatctact aggaaatcct tctgccagag aattagccca
     2701 gattatcgtg tccatcggtc ttgcccaaaa ttttgcagcc ctcaaagcct tggtaagtac
     2761 gggcatccag caaggccaca tgaaactaca ggccaaatcc ctagctctcc tagctggggc
     2821 tagtgaatct gaagttgctc ccctagtaga gcgcctcatc tcagataaaa cctttaacct
     2881 agagacagcc cagcgctatc tcgaaaattt aagatcataa aaactcagac gaatcggtct
     2941 gagttttctt gtgtttaaat actttttcct ggtaatagtg taactggtaa gaagtaacca
     3001 gttgtggcga cttccttgcc ttcaatcttt tgcaagagaa gatcaatagt gagacaagca
     3061 atctcttcca aaggttgctt gatagtagcc aattgagggt agtaattttc gataaagtag
     3121 gtcccatcat agccgataac cttgagctct tttgggacag aaatgcccaa ttcttgagcg
     3181 attttaatga tcagaatagc tgtcaaatca tccgaagcaa aaatggcatc tggtttttcc
     3241 cgggtcaaga tattcttgat ttccatttct tttctgacgg gagaaaagtc actggaaaca
     3301 ttgataatag gagcttttgg gagtacggat gcaaaaccag cgtggcgcag tccggttggc
     3361 gaattggaat tgtcattccc tgtaatcatg atgatagact gggcacctgt cttgaccaag
     3421 gtttgggcag caagaacccc accagcatag ttgtcagagg agacaacagg gatgtctggc
     3481 gataggtttc ggtcaaagga aataatcggc gctgtcacac gattgtagtc ttcgattcct
     3541 aggttgtgac taccagaaat gatgccgtct acctgattgg cttccaacat ttcgatgtat
     3601 tcgcgttcct tctcagaatc atgttcactg ttgcagatga tggtcttgta accatttttg
     3661 aagagttggt gttccaattt atcaatcaat tctgcataga aaacattgga aatattgggg
     3721 aaaatcaagc cgattaactt agctgatttt ccttgcagac tacgagccag gttgttgggt
     3781 ttatagctta attctctcat ggcttcattg actttttgga tggttttctc agatagatac
     3841 ccttttttat tgataacccg agaaacggta gtaggactga cgcctgcaag tttggcgaca
     3901 tcagttagtt ttgcgaccat aatctaattc atagtaagtt ccagttgggt ttccagattt
     3961 gatcaggata ccattttggt ccgcatgtgg gaagacacga ccagaaaata ctttttctcc
     4021 tttattgatg aaaatttcaa agacagagtt atcgatgaag attgtagcag tagtagcctg
     4081 attctcgata gggcaagaac gagttgtccc aaattcttgg gcatactgtt ctccagcctg
     4141 gctacgatcc actgtcactt gaccgtttac aaggtcaaag ttgattgaaa gtcccttacc
     4201 ttctttatca gcaagtaaga caatctcgct ctggctatta gcttccaagt tgagttcaag
     4261 ttcgtaagtg ttcttggttt gggaacggtt tgagaaggct tcttcagaag cacgaaggtc
     4321 cttaatagca gcgactggat actggtagag cttgtcgtct ttgatagtga gttccttgac
     4381 caaagagaag gttccttggt gatcaaaaca gtcagatggg taagaaacat ctggcaaacc
     4441 aagccagcta actgctagag cacgcccatc aggagcgttg aaggcttgag ttgcataggc
     4501 ttcgaaaccg taatccatgt tttgaagttg agacacatct accattttgg catttttagg
     4561 gtcaaaggaa gccccaatct tatacatatt tggaaagata ttatcgtagt ctagaacttt
     4621 cttatccaat ccttgtggac agtagagaag gacaggctgt tcctctacaa agatcagatt
     4681 aggacattcc atcatgtagg cagtacggtc gttagcaaag tcaaggtcgc caactgcttg
     4741 ccagtttgtg tagtcgttat tgacagcctt gtagagacgg acgaagcctt ttttctccaa
     4801 gtcctgtcca ccgacgacag catagtattg acctttaaag ttaaaaattt gtggatcgcg
     4861 gaagtggtca gtagagtctg ctggctggtc aatcaagatc ttgtcaatct ttgtaatctt
     4921 accctccttg tccatcaaag caccgatctg gtatgggtga cggatccagt tttcatcgcg
     4981 aacatttcct gtataaaata ggaataagtt atcgccaaat tgcatggcag aaccagagta
     5041 ggcaccgtgg ctatctaatg gagtatctgg taaaactttg attccagttt ctttaaagtg
     5101 aaccaaatca tcactttcta gctgtgccca agatttcaaa ccgtgggctg caccaaaagg
     5161 aaaattctgg taaaagagga tccacttgcc atcaaagtaa gaaaagccat ttgggtcgtt
     5221 gagaagtcct gtttttggct caacatggta atgagtatgc catggagatt gtgccatatt
     5281 ttcctttata tgttgaattt cttcttgcgt ccaatcttga taaagtctgt aacgacgctc
     5341 agttgtccat tccattcatt cctccaaaaa tcttatcact tttaatagta actgttttcg
     5401 ataaaaaatg caagcctttt atgttaaaaa agaggaaaaa ctgtcaaacg attatcataa
     5461 aataaataca ggaaatcaat caaattttta cgaaaatgtg aaagataatg aaataaaata
     5521 ctttttaacc aaggtttcaa acttattttt caaggaattc ctgatgaaac agtcaaaaac
     5581 aatcaatcta aagcttgccc actaagtgga tagaatattt ttatgcaaaa cgcttgacat
     5641 atttttaaaa catgataaaa taatagtcgt aagggcgaat aaaatcgctt tcaaacaaga
     5701 acaaaatgtt atataaggag atttttgcaa atgaacaatc aggaaattgc aaaaaaagtc
     5761 atcgatgcct tgggcggacg tgaaaatgtc aatagtgttg cccactgtgc gactcgtcta
     5821 cgtgtcatgg tcaaagatga agagaaaatc aataaagaag tgattgagaa cttggaaaaa
     5881 gttcaaggtg ctttctttaa ctcagggcaa taccaaatta tctttggtac aggtacagtt
     5941 aacaaaatgt acgatgaagt tgttgtactt ggattaccaa catcatctaa ggatgacatg
     6001 aaagcagaag ttgctaaaca agggaactgg ttccaacgtg ctatccgtac ttttggtgat
     6061 gttttcgttc caatcatccc agttatcgta gcgacaggtc tcttcatggg tgtgcgtggt
     6121 cttttcaacg ctcttgaaat gccacttcca ggtgactttg caacttacac acaaatcttg
     6181 acagatacag ccttcatcat cttgccaggt ttggttgtgt ggtcaacctt ccgtgtattt
     6241 ggtggaaatc ctgccgttgg tatcgttctt ggtatgatgc ttgtctctgg ctcacttcca
     6301 aacgcttggg cagttgctca aggtggtgaa gtaacagcga tgaacttttt tggtttcatc
     6361 cctgttgttg gtttgcaagg ttccgttctt ccagccttca tcatcggggt tgtcggagct
     6421 aaatttgaaa aagctgtccg caaggttgtt ccagatgtca ttgacctctt ggtaacacca
     6481 ttcgtgacac ttttggtcat gtctatcctt ggactctttg tcattggacc agttttccac
     6541 gttgttgaaa actacatcct tattgctaca aaagcgattc ttagcatgcc atttggtctt
     6601 ggtggtttct tgattggtgg ggttcaccaa ttgatcgtcg tgtcaggtgt gcaccacatc
     6661 ttcaacttgc ttgaagtgca attacttgct gctgaccatg ctaacccatt caacgctatc
     6721 atcacagctg ctatgacagc tcaaggtgct gctactgttg cggttggtgt taaaacaaaa
     6781 aatccaaaac tgaaaacact tgctttcccg gctgctcttt ctgccttcct aggtattaca
     6841 gagcctgcta tcttcggggt gaacttgcgc ttccgtaaac cattcttcct ttcattgatt
     6901 gctggtgcaa tcggtggtgg attggcttct atccttggac ttgctggtac tggtaatggt
     6961 atcaccatca tccctggtac aatgctttat gttggtaacg gacaacttcc acaatacctt
     7021 cttatggtag ctgtatcatt tgcccttggt tttgctctta cttacatgtt tggttacgaa
     7081 gatgaagtag acgcaactgc agctgcaaaa caagctgaag tggctgaaga aaaagaagaa
     7141 gttgcgccag cagctcttca aaatgaaaca cttgtaactc ctatcgtcgg tgatgttgtc
     7201 gctcttgctg atgtcaatga cccagtcttc tcaagtggag ctatgggaca aggtatcgct
     7261 gtgaaaccaa gccaaggcgt ggtctatgca ccagctgatg ctgaagtttc aattgccttt
     7321 ccaacagggc acgcttttgg tttgaaaaca agaaatggtg ctgaagtttt gattcatgtt
     7381 ggtattgaca ctgtatctat gaacggtgac ggttttgaag caaaagttgc tcaaggtgat
     7441 aaggtgaaag ttggcgatgt tcttggaaca tttgactcaa ataaaatcgc tacagctgga
     7501 cttgatgata caacaatggt tatcgttaca aatacagctg actacgcttc agtagctcca
     7561 gtcgcaacag gttcagttgc gaagggggat gctgtgatcg aagtgaaaat ctaatcaatc
     7621 ctctctaatg tgaaaacgaa caaatgacat gtttgttcgt ttttattaga tagtaagatt
     7681 tacagaggaa aatctaaaaa atagagacat ttagactttc gaagtatgct ataataaaga
     7741 aaataaaaac aagaggttta tcatgacaaa attatatgga agcttggaag ctggcggtac
     7801 aaagtttgtc tgtgctgttg gtgatgaaaa ctttaacgtt gtagaaaaaa cacaatttcc
     7861 aacaacaact ccaatcgaaa caatcgataa aaccattgag ttcttctcaa aattcgataa
     7921 ccttgctggt cttgcagttg gttcatttgg gccgattgat attgacaaaa actcaaaaac
     7981 ttatggcttt atcacgacga ctccaaaacc aaactgggca aatgtggact tgcttggtgc
     8041 ccttcgtcgc gccctaaacg tgccaatgta cttcacaaca gacgtaaaca gctctgctta
     8101 cggtgaagtg gttgcccgta acaatgctgg tggtcgtatc gaaaacttgg tttactacac
     8161 aatcggtaca ggtatcggtg caggcgtcat ccaacgtggt gagtttatcg gtggtgtggg
     8221 tcaccctgaa atgggtcatt attatgttgc tagacaccca atggatattg aaaaagagtt
     8281 taagggtgtt tgtcctttcc ataagggatg tctggaaggc tatgcagctg gtccaagttt
     8341 ggaagctcgt acaggtgtac gtggggaaac tattgaactc aacaaccctg tttgggatgt
     8401 tcaagcctac tatatcgctc aagctgcggt taatgcgaca gtgactttcc gcccagacgt
     8461 gattgtcttt ggtggagggg tcatggctca acaacatatg ctggaccgtg tccgtgagaa
     8521 atttacatct cttcttaatg gttacctacc agtaccagat gtgcgtgact atatcgtgac
     8581 gccagcagtc gcaggaaatg gttctgccac acttgggaac tttgttcttg caaaagaagt
     8641 ttcaaaataa agcacaaaat ccgcttggga aaccaaacgg attttttacg tgtcaaagca
     8701 tttgccagaa aaagtcaata atataggtca gaccgtaggt ataaaccacg agggtaaagg
     8761 gtttggtcag aatgatgatg gtcatgtagc gcttgaaact catcttggtc agggcagcca
     8821 gcatacagag aaagtcagct gggctaatgg gccaaatcat cataaaaata aagaagcggt
     8881 caaaacgatt gcccttatct agccagccga tgtacttgtc gtaggtgcgc ttgctgacga
     8941 cagactggac aaaggcagct ccgtataggc gcactagata aaagataatg gcacagccaa
     9001 tcacgatgcc gatatagttg tagatagtcc cgatgatgtg cccgtagata aagaccccag
     9061 ccaccgaggt caaggcccct ggaatgatag ggacgacagt ctgtaaaatc tgtaaaaaga
     9121 taaagagagg tggaccccag atgcctgcct gctggataaa ggcagagagg gtttccttgg
     9181 attgtaaaat cccagcctga taagcccaaa tacagaaaat caaactccca accccaccga
     9241 caatcgatga gatattgata actcgctgca aaaggggaga aacagctttc atttgtttat
     9301 cctgtgacat gtaaactcct catagatagt atatttctac tataccatat tttggaggag
     9361 aaagggggaa tgagtctttt ttgataagga atagaaagta aatagccctt cgagacttag
     9421 aataggtctg tcaactaaag gttatatgca ttctaggttt caaataatcg caattccata
     9481 aatttaaaag cattctaagt ttcgaatagc ttatctgaga taattttgag gcattcgcgc
     9541 tttcgaatag tcattttccc taaagtttag atgtattctg aagctagaaa gactaaaatc
     9601 taaaagtagt aagagtctct ctctgatgga cgtaatttat ggctagtatg aatcctttga
     9661 attgttagtt aattttaata ttaatcagtt ctgaaataat tactaaatat agttagatgg
     9721 tgaattaatt attgctaaat ttcaagttca agttagtcat ccagaagtct tctctggggg
     9781 acttgtagtt caagcatttt ttaggatagt tgttaatcca cttttcgatg aatgcgactt
     9841 cctttgtagt cgttttctta gtttcctgag gtaactatct atgaatgagc ctgttgtgat
     9901 tttcattaga tcctataggg gtgtgcataa tagatatagc agattgaaac tagaatagta
     9961 tacatctact tctaaaacat tgttagaaat caatttgact gtcctgatca atttgtcctg
    10021 ttcttatttc attttactat ataatcctta gaaaacatat gggacaagcg gttgaattct
    10081 gttccgtcca ttagtagata aaggattact ccttcttgaa atgacagatg aacttgtttc
    10141 ttataaaaat gttgtctgaa actattagcc tttttccaga agttttagag gaagaaaact
    10201 ttacgaggaa aaaggagtta ctcaaataac aattcaggat taaaaataga cagttgagga
    10261 gcggaaggta taaattaagt ttgctgctgt ataatggatt tatcactaat actcttcgaa
    10321 aatctcttca aaccacgtca gcttcgcctt gccgtagata t
//
LOCUS       DAVBOM010000070         9806 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBOM010000070 DAVBOM010000000
VERSION     DAVBOM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.071"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            198..293
                     /locus_tag="VQ878_001915"
                     /pseudo
     CDS             198..293
                     /locus_tag="VQ878_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VQ878_001916"
     CDS             complement(546..1166)
                     /locus_tag="VQ878_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3096210.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VQ878_001917"
     CDS             complement(1166..1648)
                     /locus_tag="VQ878_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET3096211.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VQ878_001918"
     CDS             complement(1648..2490)
                     /locus_tag="VQ878_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET3096212.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VQ878_001919"
     CDS             complement(2585..3385)
                     /locus_tag="VQ878_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET3096213.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VQ878_001920"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VQ878_001920"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET3096214.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILESLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNKRLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VQ878_001921"
     CDS             4918..5463
                     /locus_tag="VQ878_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3096215.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VQ878_001922"
     CDS             5475..5789
                     /locus_tag="VQ878_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET3096216.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VQ878_001923"
     CDS             5806..6498
                     /locus_tag="VQ878_001923"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET3096217.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIVSHEVV
                     LVESGIGKVMSAMSVAILAVHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VQ878_001924"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VQ878_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET3096218.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7140..7730
                     /locus_tag="VQ878_001925"
     CDS             7140..7730
                     /locus_tag="VQ878_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET3096219.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7739..9502
                     /locus_tag="VQ878_001926"
     CDS             7739..9502
                     /locus_tag="VQ878_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET3096220.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9716..>9806
                     /locus_tag="VQ878_001927"
     CDS             9716..>9806
                     /locus_tag="VQ878_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3096221.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQI"
BASE COUNT         3037 a         1703 c         2084 g         2982 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatattagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgaaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaaatctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga actcctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agctttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 tcgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaaag tttgtcagga cacaccttgg tcattgcagg agatactcct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaaca agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatgttgaga ttgcttcgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tggatgataa tgaggaaact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaagat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg tttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgttcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aagaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtagaggag aggtacagaa
     7141 tggaacgatt agaagattac attgcttttg acttagaatt taatcagcac gaaggacaaa
     7201 cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc gatgcctatg
     7261 attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg accgggatta
     7321 cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa ttccaagagt
     7381 ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta cctattttag
     7441 cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat gaagcttttg
     7501 aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact gttgcctcat
     7561 ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg acggcgcgtg
     7621 tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca gaaagtagct
     7681 tatcaaacaa tccttttggt gtcttggact tgtctcaatt atttgactag gagtgcctat
     7741 gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc ttgataaaat
     7801 cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac cattcaattc
     7861 atggttggct agcttcttat tagatcagac aggttatctt tttatttcct ataacaatgt
     7921 cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct tgattgtaat
     7981 taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc gtcatctcct
     8041 ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg aaagttttgg
     8101 atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata tagctatgct
     8161 gtttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg tcattccaga
     8221 gtttatccaa gcttatttag aagatagata ttggatgtgg tggctgagca tcctacttct
     8281 atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga agattgtata
     8341 tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca agaagagagt
     8401 tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat tattttatct
     8461 tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc agagagagtc
     8521 tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata tggctctgac
     8581 ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata tgcttcctag
     8641 gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc ttttctttgc
     8701 cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac ttatttctca
     8761 ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg aaactacagc
     8821 acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg ggcagtttgt
     8881 catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc ctcaagactt
     8941 aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga ctaaaatttc
     9001 aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac taattgaaat
     9061 taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc gttatgctgc
     9121 aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg tcgaaaaagt
     9181 aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt ctgtctttcc
     9241 taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat attttgtaag
     9301 caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt cagaagctat
     9361 cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg aaaaagttca
     9421 gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct tgaaaaaagc
     9481 attggaattc tttgaatttt agtaataaaa aagaggaacg gttgttcctc ccatgatagg
     9541 taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga gaattgtttg
     9601 tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta cactataact
     9661 tataaaatat agtaaaatga accaaaaata gtacacaatg tggtataatc tttttatggc
     9721 atattcaata gattttcgta aaaaagttct ctcttattgt gagcgaacag gtagtataac
     9781 agaagcgtca cacgttttcc aaatct
//
LOCUS       DAVBOM010000071         9740 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBOM010000071 DAVBOM010000000
VERSION     DAVBOM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.072"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VQ878_001928"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VQ878_001928"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3096222.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VQ878_001929"
     CDS             1085..2809
                     /locus_tag="VQ878_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096223.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VQ878_001930"
     CDS             2811..4559
                     /locus_tag="VQ878_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096224.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEVSREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYDNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4816..6075
                     /locus_tag="VQ878_001931"
     CDS             4816..6075
                     /locus_tag="VQ878_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET3096225.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6151..6286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6325..6825
                     /locus_tag="VQ878_001932"
     CDS             6325..6825
                     /locus_tag="VQ878_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET3096226.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6901..7269
                     /gene="rplL"
                     /locus_tag="VQ878_001933"
     CDS             6901..7269
                     /gene="rplL"
                     /locus_tag="VQ878_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET3096227.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7456..7629
                     /locus_tag="VQ878_001934"
     CDS             7456..7629
                     /locus_tag="VQ878_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096228.1"
                     /translation="MQKKGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVEILVLEGQS"
     gene            7626..8222
                     /locus_tag="VQ878_001935"
     CDS             7626..8222
                     /locus_tag="VQ878_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3096229.1"
                     /translation="MKRITASQYQTSERYYKLPKLLFESERYKNMKLEVKVAYSILKD
                     RLELSLNSGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHEIPLVLHSDGASVKNRLGQSQKQTGPFLNSAPSETEESETDS
                     LFIEDEEERDTQPILKRKVEKVTKYDRDYIWGLVQDQF"
     gene            8259..8396
                     /locus_tag="VQ878_001936"
     CDS             8259..8396
                     /locus_tag="VQ878_001936"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096230.1"
                     /translation="MTDFERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGG
                     G"
     gene            8495..9740
                     /gene="dcm"
                     /locus_tag="VQ878_001937"
                     /pseudo
     CDS             8495..9740
                     /gene="dcm"
                     /locus_tag="VQ878_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
BASE COUNT         2900 a         1839 c         2178 g         2823 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga ctgatcaaga
     2401 actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa aacaaaggct
     2521 gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg atgcgacctc
     2581 agcactggac accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 catgagctta attttgatct ctcaacgaac ctcgacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 tcaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag tcgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgagagcga atcatccata
     3121 aactccatcg gttaccgatt gcttttgcgg atcggcaagg caatggagag atggtcagtc
     3181 gtgtaaccac ggatatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggggtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag ttgtctatcg
     3901 atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagtca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tgataaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa ttaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     4741 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
     4801 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
     4861 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
     4921 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
     4981 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
     5041 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
     5101 tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat gctccagtca
     5161 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
     5221 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
     5281 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
     5341 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
     5401 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
     5461 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
     5521 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
     5581 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
     5641 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
     5701 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     5761 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     5821 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     5881 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     5941 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     6001 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     6061 acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc aaaaatcttg
     6121 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     6181 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     6241 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     6301 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     6361 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     6421 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     6481 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     6541 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     6601 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     6661 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     6721 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     6781 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     6841 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     6901 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     6961 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     7021 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     7081 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat tactggtctt
     7141 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     7201 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     7261 cttaaataat agagtatcgc aatttaattg cggaatccct atttaccagt ctttgagagc
     7321 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     7381 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     7441 gtttcggagg taattatgca aaagaaagga cagtcatcac gtcaattcgt gaagagtcat
     7501 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     7561 caagtaggtt taatccgatt tgatgaattt ggaaatgttg aaattttagt cttggaggga
     7621 caatcatgaa gcgtattacc gctagtcaat atcagacatc agagcgttat tataagctcc
     7681 ccaaactttt atttgagagt gaacggtata agaatatgaa actagaagta aaggtggctt
     7741 attctatttt aaaagatcgt ttagaattat ctctcaatag tggttggata gatgaagaag
     7801 gggcggtcta tttagtattt tctaactcta aactgatgaa gcttttaggc tgttcaaagt
     7861 caaaattact ctccatcaag aaaactttac gtgagtatgg cctaattgat gaagtccaac
     7921 agtcttccag tgaaaaaggt cgtatggcta ataaaattta cttaggggaa ttagaacatg
     7981 agatacccct agtcttacat tcagacgggg ctagtgttaa aaacagatta gggcagtctc
     8041 aaaaacagac ggggccgttt ttaaattcag cccctagtga gactgaagaa agtgagactg
     8101 attctttatt tattgaggat gaggaggaga gggatactca acctatcttg aaaagaaaag
     8161 tagaaaaggt cacaaaatat gatcgagatt atatttgggg attggtacaa gatcaatttt
     8221 gacgagaggg gttttctgaa acagccagtg aaattgctat gactgatttt gagagaatct
     8281 atcagtatgc tcttgacaat gttcgctttg ttagacgagc ggaagtactt gctgaatttg
     8341 tgtttaacgg cctatattct gtttggaata accgtgttag aaaaggaggt ggttaaatgt
     8401 cgccaatcga gtggatatta gttatgctca ttttaatttc aagtggtgtg acactttgga
     8461 cattgatagt tgttcagaaa ggggtaatca agaaatgaga tttattgatt tattttcagg
     8521 tatcggtggt tttcgacttg gaatggaaag tgtcggacac gagtgtattg gattttgtga
     8581 gattgataaa tttgctagag aatcttataa gtccattttt caaacggaag gagaaataga
     8641 atatcatgac attaaagagg taacagatca tgactttaga caatttagag ggcaagtgga
     8701 catcatctgc gggggatttc cttgccaagc tttttcactt gcaggaagac gattgggatt
     8761 tgaagatact agaggaactt tgttctttga aattgctcgg gcggccaaac aaatccaacc
     8821 acgttttctt tttcttgaaa atgttaaagg cctactcaat cacgataagg gacggacgtt
     8881 caccacaatc cttaccacat ttgatgagtt ggggtttgat gttgagtggc aggtgcttaa
     8941 cagtaaggat tttggcgttc cccaaaacag agagagggtg tttattatcg gacattctag
     9001 aaagaaaggt accagactct tatttccttt cagacgagaa ggtcaagcaa ctaactctga
     9061 gactttgaaa gcactaggaa atttgaatcc atcaaaaagt ggcgtgagcg gtaaagtgta
     9121 ttattcagaa ggtcttgcgc caactttagt tcgtggaaaa ggagaaggat ttaaggttgc
     9181 tattccttgt atgacaccag atagattaga caaaagacaa aatggtagac gctttaagga
     9241 aaaccaagag ccgatgttta ctttaaatac tcaggatcgt catggcattg tcgttgttgg
     9301 agatttaccg actagtttta aggagacagg tcgtgtctat ggaagtgagg gcttatctcc
     9361 aacactgact acgatgcaag gaggagataa aatccccaaa atactaattc cagaaccaat
     9421 ccaatttcta aaagtacggg aagcaacgaa aaaaggatat gctcaagcag agattgggga
     9481 ttcaatcaat ttggaaagac caagttctca gtatcgtcgt ggtagagttg gcaaaggtat
     9541 agctaatacg ttaacaactg tggtagagtt ggcaaaggta tagctaatac gttaacaact
     9601 agtggtcaaa tgggagtagt agtggctagc tatgaaggag aagataaaca agtttaccaa
     9661 gtagctggtg ttttaataga tggacaattt taccgtttga gaatacgacg aatcactcct
     9721 aaagagtgtt ttcgattgca
//
LOCUS       DAVBOM010000072         8994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBOM010000072 DAVBOM010000000
VERSION     DAVBOM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.073"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(358..1965)
                     /locus_tag="VQ878_001938"
     CDS             complement(358..1965)
                     /locus_tag="VQ878_001938"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET3096231.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VQ878_001939"
     CDS             complement(2355..2942)
                     /locus_tag="VQ878_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET3096232.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VQ878_001940"
     CDS             complement(3070..3519)
                     /locus_tag="VQ878_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3096233.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VQ878_001941"
     CDS             complement(3524..3913)
                     /locus_tag="VQ878_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET3096234.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VQ878_001942"
     CDS             complement(3941..4567)
                     /locus_tag="VQ878_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3096235.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VQ878_001943"
     CDS             complement(4581..5144)
                     /locus_tag="VQ878_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3096236.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VQ878_001944"
     CDS             complement(5597..6100)
                     /locus_tag="VQ878_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET3096237.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VQ878_001945"
     CDS             complement(6293..7123)
                     /locus_tag="VQ878_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3096238.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VQ878_001946"
     CDS             complement(7108..8790)
                     /locus_tag="VQ878_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096239.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         2723 a         2058 c         1636 g         2577 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata gctggtcgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccaaca
     4501 tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt caaaaggacg
     4621 tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaaca
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac aaatgagatg
     5101 gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaggaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cccgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttata aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catatcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctga
     7921 ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc
     7981 cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga gagtggttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg
     8161 cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagc
//
LOCUS       DAVBOM010000073         8327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBOM010000073 DAVBOM010000000
VERSION     DAVBOM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.074"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(549..857)
                     /locus_tag="VQ878_001947"
     CDS             complement(549..857)
                     /locus_tag="VQ878_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3096240.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VQ878_001948"
     CDS             complement(854..1162)
                     /locus_tag="VQ878_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3096241.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VQ878_001949"
     CDS             complement(1167..2462)
                     /locus_tag="VQ878_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3096242.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VQ878_001950"
     CDS             complement(2480..3889)
                     /locus_tag="VQ878_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3096243.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VQ878_001951"
     CDS             4047..4775
                     /locus_tag="VQ878_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3096244.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VQ878_001952"
     CDS             5234..5428
                     /locus_tag="VQ878_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3096245.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5793..7103)
                     /locus_tag="VQ878_001953"
     CDS             complement(5793..7103)
                     /locus_tag="VQ878_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET3096246.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7340..8212
                     /locus_tag="VQ878_001954"
     CDS             7340..8212
                     /locus_tag="VQ878_001954"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET3096247.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2589 a         1457 c         1583 g         2698 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 cgtcatattt ttcatattct tgaatccatc gataaagact attgggatga atttttaaag
     5641 ttgaactaat tatttttaca ggatgaggtt tacagcagag agtttgaagg ctttatcaaa
     5701 ggtttttctt ggcataatga cttttcctcg tttccactta attttgtgtc tactttatta
     5761 taccaagtcc acccttaagt tagataatga atctaactta aggaagctag aaggatgaga
     5821 atccaggtgg tcaagagtcc caaacttaag ctgataggga cacccagaat aatttgcttt
     5881 ttgaaggcaa gaccgcgttc ctctatattg gggagtgaga gttgaatgag agaaccagct
     5941 gatgaaaagg gtgagatatt agtagataga gcgccaataa cggtggctgt tgtgagtaag
     6001 tgaatatcaa tctgaggatt ttgagcactg atgatagcaa tgatgggaaa gagggctgga
     6061 gctacaacgg atagggtgga actaaagagt gacatcactc cggctatcac acaaaagaac
     6121 agaggtaacc agaaatgagg aatggttgtt gtcatgaggt gccctatcag tgtgactaaa
     6181 cctgacttga ccgctagaga cattagtaag ctcatgccgc agagcatgat aattgtagcc
     6241 cagggaactt tagccaaaat ggcttcttgc ttccctaatt tgagccttaa ggcgaggcag
     6301 accatgagta ttgagacaaa gccaatatca aatgtttttt gataagtagc tatccaggcg
     6361 atgtttggga aaatgagatg caacaaggga aaaagccaaa ccaaaaccat gctgctgatc
     6421 atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg gtggttggtc aatagtcaag
     6481 gatgagtttg ttcttccctt actatagtgg ctgtaacagg ataataaaag caagacgatg
     6541 agtgggtaga taatgctgac gataaagata tgattgccaa gtgaaaaagc ttgctcttcc
     6601 catcccattt gcttaaacag gccttgaaag acaatgcctg agctactggt tatcaaatta
     6661 gcccctcctg aagctcccca attgacggct tgagctccaa tcaaagggtg tttgtccgct
     6721 ttttgacaga gggtaatcgc tagaggacag caaacggcca tagtagtgaa aaatccagca
     6781 cctaaagcag acaaaagggt tgccatcagg tataaaatca tgtagagggc gttaggatgg
     6841 gtgcgtgtgc ggtagagaat gtgttgagcc aagacatcaa gagtaccgtt agttgttgca
     6901 acgttataaa agagagagac gctaaaaatg gtaaaaaaga gtgaggttgg ccaaaaatga
     6961 agaagttctt tggggcttaa tcccatgaga gtggttgcga tgaggtaaga aaaagcaata
     7021 gccagcaggc caatattgat tttggtgcgg taaccaattc caatggctag agcaatggcg
     7081 ctaatcatta ttaaatgaat cattgaattg tcctttcagt tagaatatgg aaataggttg
     7141 gcaattttgg cgctcaaaag accacctgtt tcctattggt acttgactat tatacacaaa
     7201 aaaaatacaa ttgtcttgac aattgtattg acacttgtta gaattaaaaa tgaggtattc
     7261 aggcttgtga tttcctatgg aagttcatag tgattgcctc tagtgcttac aagtgatatt
     7321 aaaaatagag gatctagtga tgtcaatcat ttcaactgat ttaacccctt ttcaaataga
     7381 tgatacattg aaagcagcct tgcgagaaga tgttcattcc gaagattaca gtaccaatgc
     7441 catttttgat catcatggcc aagccaaggt gtcgcttttt gccaaggaag ctggtgtttt
     7501 agcggggcta accgtttttc aaagggtttt taccctattt gatgccgagg tgaccttcca
     7561 gaatcctcat caatttaagg atggggatcg tttgactagt ggcgatttgg ttttagaaat
     7621 cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt gccttgaatt ttttacaaca
     7681 tttatcaggg attgcttcga tgacagctgc ttatgtagaa gccttaggcg atgattgcat
     7741 taaggtattt gatactcgaa aaactactcc taatttacgt ctttttgaga aatatgccgt
     7801 gagagttggc ggtggctata atcatcgctt taatttatca gatgctatcc tgctaaaaga
     7861 caatcacatt gcggcagtag gtagtgttca aaaggcaatt gctcaagcgc gtgcctatgc
     7921 cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt gctgctgccg aagaagctgc
     7981 ggcggcgggt gctgatatta tcatgttgga taatatgtca ttggaacaga ttgaacaggc
     8041 cattacccta attgcaggac gttctcggat tgaatgttct ggaaatattg atatgaccac
     8101 tattagccgt tttcgtggtt tagcgattga ttacgtctcc agtggtagtt taacccatag
     8161 tgctaagagt cttgattttt ccatgaaggg gttaacctac cttgatgtct aagttgtaaa
     8221 ataaactaac tttttaaagg atgtctttcc tctagaacga gttttatgtc agatagttta
     8281 aacgcctctt caaatatagt aaaatgaacc aaaaatagta cacaatg
//
LOCUS       DAVBOM010000074         8262 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBOM010000074 DAVBOM010000000
VERSION     DAVBOM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.075"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ878_001955"
     CDS             226..6657
                     /locus_tag="VQ878_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET3096248.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6953..7299)
                     /locus_tag="VQ878_001956"
                     /pseudo
     CDS             complement(6953..7299)
                     /locus_tag="VQ878_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7394..7579)
                     /locus_tag="VQ878_001957"
                     /pseudo
     CDS             complement(7394..7579)
                     /locus_tag="VQ878_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7607..7834
                     /locus_tag="VQ878_001958"
     CDS             7607..7834
                     /locus_tag="VQ878_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3096249.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7910..8262
                     /locus_tag="VQ878_001959"
                     /pseudo
     CDS             7910..8262
                     /locus_tag="VQ878_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3138 a         1162 c         1625 g         2337 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttatataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccatttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccgtatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatatactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa tagccattta taactcaatt atttagttta ctttacttta ctagtgatac
     6781 tatttggagt tattaatgga cttagtttat ataactaatg aattgattga aagggttagt
     6841 attgacaata ttggtcatat tgactagaaa atagagtcta tcaaaattta aaggctaata
     6901 gaggtgatga gacaatttcg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
     6961 gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgatgaaa atccgttttt
     7021 tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat
     7081 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcattgaca atcttctctt
     7141 tatctttgag gaaggtttta gaggatgaac ttgattcaga ttgtcctcaa tgagtccgaa
     7201 aaatttgtca ggctccttat tctgaaagtg aaaaagcaag agttgataga gattatagtg
     7261 gtgtttcaag tcttctgaat agctcaaaag tttatctata gtagattgaa actagaatag
     7321 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgaa tgatttgtcc
     7381 tgttattatt tcattttact ataaatccac gtttacgaat ctctttccac acttgttcaa
     7441 tggggttcat ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct
     7501 ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaga taatcatctg
     7561 gataagcttg tgaaagctcc tattcctaaa gcccctttat aacctcttgc gagagagact
     7621 attgactcag cccttacttc atgcggatga aacttcttat cgggttctag agagtcatag
     7681 ccatctgacc tactattgga cctttttgtc tgggaaagtt gagaatcaag caatcacgct
     7741 gtaccatcat gatcagagtc ggagtggttc ggtagtacaa gaattcctag gagattattc
     7801 tggctatgtt cattgtgata tgttgcggca gtaacttagg actttagtcc tctagttctg
     7861 cctatgcgat agcagtccaa ggtttaggag caaggcgacg ctaagcttgg taaactgcga
     7921 accgctagaa gcttatcgtc aactggcaga agctgaactt gttggatgtt gggcgcatgt
     7981 gagaaggaaa ttttttgaag cgacccccaa gcaagcagat aaatcatcct taggagctaa
     8041 aggtttagct tattgtgatc agttattttc cttggaaaga gactgggagg ctttgccagc
     8101 tgatgaacga ctacagaaac gtcaagaaca tctccagccc ctaatggaag acttctttgc
     8161 ttggtgccgc cgtcagtcag ttttagcagg ttcaaaacta ggaagggcaa ttgaatacag
     8221 cctcaagtat aaagaaacct ttaagactat tttgaaagac gg
//
LOCUS       DAVBOM010000075         7478 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBOM010000075 DAVBOM010000000
VERSION     DAVBOM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.076"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            151..306
                     /locus_tag="VQ878_001960"
                     /pseudo
     CDS             151..306
                     /locus_tag="VQ878_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            506..3781
                     /gene="rexB"
                     /locus_tag="VQ878_001961"
     CDS             506..3781
                     /gene="rexB"
                     /locus_tag="VQ878_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET3096250.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3778..7428
                     /gene="addA"
                     /locus_tag="VQ878_001962"
     CDS             3778..7428
                     /gene="addA"
                     /locus_tag="VQ878_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET3096251.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLERFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLSSVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2275 a         1573 c         1592 g         2038 t
ORIGIN      
        1 tgtactattt ttggttcatt ttactatagt agattgaaat aagatacgaa cagcttgatt
       61 agggaaatca aattaatttc tagaaatatt ttagcatcca cggtgtacta ttatagtttc
      121 aatttactat agttcaatca ttctatcaag aatattgaat atataaaggc acgtaatatt
      181 aaaacttctt ctgatatcga attagagtcc gatgttgatg gcgataaatc agacaatcta
      241 ccagtcgaca ttaagatact gggacaacac attgaagtgt attccgtacc taagaaacaa
      301 tcataaaact caaagccttg ttaccgaggc ttttttatta tgtgattttc agtagccaga
      361 cttattctat ctaatacaag taaagctaag tatttaagat ttagcagatg atgaagaaaa
      421 gaaaggatgg cctaaatatt ttaacagatt tacgaggcta atcatggtat aatatagggt
      481 gatgaaaaat tccaacgagg ctgagatgaa attactttat actgatattc ggacttcttt
      541 gacagaaatt ctaacaagag aggcagaaga gctagttgca gctggcaagc gggtcttcta
      601 cattgccccc aactctcttt cttttgaaaa ggaacgcgcc gtgctggaat gcttgtccca
      661 gcaggcttct ttttcgatta ccgtcacgcg ctttgctcaa atggctcgtt atctggtctt
      721 gaatgattta ccagctaaaa ctactcttga tgatatcggt cttgggttgg ccttttacaa
      781 atgccttgcc gaactcgatc ccaaggactt gcgtgtttat ggcgctatta agcaggatcc
      841 tcaattgatc cagcagttaa ttgagcttta ccatgagatg accaaatccc agatgagttt
      901 tttggacttg gagaatttaa cagatgagga taagagggcg gatttactct tgatttttga
      961 gaaagtaaca gcctatctta atcaaggtca gttagcccag ggaagtcagt tgtcccattt
     1021 gattgaggct attgagaatg acaaggtaag tagtgatttt aatcaaatca ccttggtcat
     1081 tgacggcttt actcgttttt ctgctgagga agagcgggtt gtggacttac ttcacggcaa
     1141 aggtgttgag attgttatcg gggcttatgc tagtaagaaa gcctatacca gtccttttag
     1201 cgagggcaat ctctaccaag ccagcgtaaa atttctccat catctggctt ctaaatacca
     1261 aacgcctgct caggactgtt ctcaaactca tgagaagatg gatagttttg acaaggcctc
     1321 tcgtttgttg gagtcttctt atgacttttc agaactcgct ttggatgtcg atgagaaaga
     1381 ccgtgaaaat ttacaaatct ggtcttgttt gacgcaaaag gaggagttgg agctagtagc
     1441 ccgtagtatt cgtcagaaat tacatgagaa ctcagacctg agctacaagc attttcgtat
     1501 tctcttgggg gatgtagctt cttaccagtt atctctcaaa accatttttg accagtatca
     1561 gattcctttt tatcttggta gaagcgaagc catggctcat catcccttga ctcagtttgt
     1621 cgagtctatt ttagctttaa aacgttaccg ttttcgtcag gaggatttga ttaatcttct
     1681 tagaactgat ttgtatactg acctcagtca gtctgatatt gatgcttttg agcaatatat
     1741 ccgctatctt ggtatcaatg gcttgccagc ctttcagcaa atcttcacca aatcccacca
     1801 tggaaaattt aatcttgagc gtttgaatgt cctccgcctg agaattttag cacctcttga
     1861 aaccctcttt gccagccgaa aacaaaaggc tgaaaacctc ctacaaaaat ggagtgtctt
     1921 tctaaaagaa ggagctgtga ccaagcagtt acaagatttg acaaccactt tggaagctgt
     1981 agaacaggaa agacaagccg aagtttggaa ggctttctgc catgttttag aacaatttgc
     2041 gactgttttt gctggttcac aggttagtct ggaagacttc ctagccttgc tccattctgg
     2101 aatgagtttg tcccaatacc gtaccattcc agcaacagtg gacactgttc tggtgcagag
     2161 ttacgatttg attgcaccat tgactgctga ctttgtctat gctattggac taactcagga
     2221 caatttacca aaaatttctc aaaacaccag tcttctgaca gatgaagaaa ggcaaaacct
     2281 aaaccaagcg accgaagaag gcgttcaatt actgattgcc agcagtgaaa atctcaagaa
     2341 aaatcgctac actatgcttt ccttggtcaa ttctgctcgt aagcagttgt tcttgtcggc
     2401 tccaagcctt tttaacgaaa gtgaaagtaa ggaatctgcc tatcttcaag agttgatcca
     2461 ttttggattt aggcggagag agaagaggat gaatcacaaa ggactgtcta aggaggatat
     2521 ggggtcctat cacagtcttt tgtctagtct ggttgcctat caccagcagg gtgagatgag
     2581 cgatactgag caagatttga cttttgtcaa ggttctgtcg cgtgtcatag gtaaaaaact
     2641 agatctgcaa ggtctggaaa atccagctat cccaaccagt ccaagcagca agaccttagc
     2701 caaggacacc ttgcaagctc tctatcctgc caaacaggag ttttacctgt ctacgtcggg
     2761 tttgacagag ttttatcgca atgaatacag ttatttccta cgctacgttt taggcttgca
     2821 ggaggaatta cgtttgcgtc ctgatgcccg tagtcacggg aatttcttgc atcgtatctt
     2881 tgaacgcgcc ttacagttgc ctaatgaaga ttcctttgac caacgtctag aacaagctat
     2941 tcaagaaacc agtcaagaac gcgaatttga agctatttat caagaaagtt tggaagccca
     3001 gtttaccaag gaagttttgc ttgatgttgc acggacgact ggacatattc tccgacacaa
     3061 tccagccatc gaaaccatca aagaagaagc aaattttggt ggaaaagacc aagcctttat
     3121 tcaattagac aatggacgca gtgtctttgt acgaggcaag gtggaccgga ttgaccgttt
     3181 gaaagctaat ggagcgatag gagtagtaga ctacaaatcc agtctgactc agttccagtt
     3241 tcctcatttc tttaatgggc tcaattctca gttaccaacc tatcttgctg ccctaaaaag
     3301 agaagggaag cagaactttt tcggcgccat gtacttggaa atggctgaac ctgtccaatc
     3361 tctgatggcg gtaaaaagtc tggcaggagc agtggtagaa gccagcaaat ctatgaaata
     3421 ccaagggctc ttcttggaaa aagaaagcag ttatttaggc gaattttata acaaaaacaa
     3481 ggctaatcaa ctgacagatg aggaatttca gctcctactg gactacaatg cctatcttta
     3541 caagaaagct gctgagaaga ttttagcagg ccggttcgcc atcaatcctt atactgaaaa
     3601 tggcagaagc attgccccat acgtccagca acatcaggct attacaggct ttgaagccaa
     3661 ttaccatctg ggccaagccc gtttcctaga aaaattggac ctagctgatg gcaagcgtct
     3721 ggtcggagaa aaactcaagc aagcttggtt tgaaaaaata agagaggagt taaatcgatg
     3781 aagcttattc cctttttaag tgaggaggag attcaaaaac tgcaagaagc agaagcaaat
     3841 tcgagcaagg aacagaagaa aactgccgaa caaatcgaag ctatctacac ttctggtcag
     3901 aatatcctgg tctcagcatc ggctggttct ggaaagacct ttgtcatggc agagcgcatt
     3961 ctggaccaat tggcgcgtgg tgtcgaaatt tctcaactct ttatctcaac ctttaccgtc
     4021 aaggctgcaa ctgaacttaa agaacgttta gagaaaaaaa tcagcaagaa aatccaagaa
     4081 acagatgatg tcgatctcaa acaacacttg ggtcgccagt tggcagacct acccaacgct
     4141 gccatcggaa ccatggactc tttcacacaa aaattccttg gcaaacatgg ttatctgctt
     4201 gatattgcac ctaatttccg tattttacaa aaccaaagcg agcaacttct tctcgaaaac
     4261 gaagtctttc atgaggtctt tgaagcgcat taccaaggta aacagaaaga gagctttagt
     4321 catttgctga aaaactttgc tgggcgtggc aaggacgaac ggggtctgcg gcagcaagtc
     4381 tataaaatct atgacttcct ccaatccacc agtaatcctc aaaagtggct gagtgaatct
     4441 ttcctcaaag gctttgagaa agctgatttt accagtgaaa aagaaaaact gactgagcaa
     4501 atcaaacaag ccctctggga tttggaaaga tttttccgtt accatctgga taacgatgcc
     4561 aaggagtttg caaaggctgc ctatttagaa aatgttcagt taattctgga tgaaattggc
     4621 tccctaaatc aggagttcga tagtcaggct tatcaggcag tacttgcgcg tgttgtcgcc
     4681 atctctaagg agaaaaacgg tcgtgctctg actaatgcca gccgtaaggc tgatttgaag
     4741 cccctggctg atgcctacaa cgaagagaga aagacccagt ttactaaact aggacaatta
     4801 tcagaccaga tagcgattct cgactatcaa gaacgttatc atggagacac ttggaaacta
     4861 gctaaaacct tccaatcttt catgagcgat tttgtagagg cttatcgtca gagaaaacga
     4921 caggaaaatg cctttgaatt cgctgatatc agccattaca ccattgagat tttagaaaat
     4981 ttcccacaag ttcgtgagtc ttatcaggag cgcttccatg aagtcatggt cgatgagtat
     5041 caggatacca accatattca agaacggatg ctggaattgt tgtctaatgg ccacaatcgc
     5101 tttatggtgg gagatatcaa gcaatccatc tatcgtttcc gtcaggcaga cccgcagatt
     5161 ttcaatgaga aattccaacg ctatgcgcaa aatccccaag aaggcaagct cattctcctc
     5221 aaggaaaatt tccgtagtag ttcagaagtg ctgtcagcaa ccaatgatgt ctttgaacgt
     5281 ctcatggacc aagaggtcgg cgaaatcaac tatgataaca agcaccagct tgtttttgcc
     5341 aataccaaac tgactcccaa tccagacaac aaggcagaat ttctcctcta cgacaaggac
     5401 gatacaggtg aggaagaaga gagtcaaaca gaaacgaaac taacaggcga aatgcgctta
     5461 gttatcaagg agattctgaa acttcatcaa gaaaaaggtg ttgcctttaa ggaaattgcc
     5521 cttctgacct ccagccgcag tcgtaatgac cagattctcc tcgccctgtc tgagtacggg
     5581 attcctgtca aaactgacgg agagcaaaac aattatctcc aatccctaga agtgcaagtc
     5641 atgctagaca ctcttcgtgt cattcacaat cccctgcaag actatgcctt ggttgccctt
     5701 atgaagtctc caatgtttgg ttttgatgag gatgagctag cacgtttgtc ccttcagaaa
     5761 gcagaggata aagtccacga aaatctctat gagaaactgg tcaatgcaca aaaaatggca
     5821 agtagtcaaa aaggcttgat tcacacagct ctagctgaaa aactaaagca attcatggat
     5881 atcctagctt cttggcgctt gtatgccaaa acccactctc tctatgactt gatttggaag
     5941 atttacaacg accgttttta ttatgactat gttggggctt tgccgaatgg tcctgctagg
     6001 caggccaatc tctatgccct agcactgcgt gctgatcaat ttgaaaagag caatttcaaa
     6061 ggtttgtcgc gttttattcg tatgattgac caagtcttag aagcccagca cgatttgtca
     6121 agcgtggccg tcgcaccgcc aaaagatgca gtagagctca tgaccatcca caagagtaaa
     6181 gggctggagt ttccttacgt ctttatcctc aatatggatc aagatttcaa caagcaagac
     6241 tctatgtcag aagtcattct cagtcgtcag aatggtcttg gtgtcaaata tattgccaag
     6301 atggagacag gggcagtaga agaccactat cctaaaacca tcaaactctc cattcctagt
     6361 ctgacctata ggcagaacga agaggaatta cagctagcaa gctattctga gcagatgcgt
     6421 ttgctgtatg ttgctatgac gcgggctgag aaaaagctct atcttgtcgg caagggttct
     6481 cgtgaaaagc tggaagtcaa gcaataccca gcagccaaaa atgggaaact aaatagcaat
     6541 actagactgc aagcacggaa tttccaagat tggctttggg ctatcagtaa agtgtttact
     6601 aaggacaagc tcaactttag ttatcgtttt attggcgaag atcagttgac cagagaagct
     6661 atcggagagt tggaaaccaa gagtcctctc caagatagct cccaagcaga caatcgtcag
     6721 tcagatacca tcaaagaagc tctggaaatg ctgaaggagg tggaagttta taatactctt
     6781 caccgcgcag ctattgaact tcctagtgtt caaaccccaa gtcaaatcaa gaaattctac
     6841 gaaccagtta tggatatgga aggtgtcgag attgctggtc aaggtcagtc agtaggcaag
     6901 aaaatcagct tcgatttgcc agatttttca accaaagaaa aggtaactgg agctgagatt
     6961 ggtagtgcta ctcacgaact catgcagaga attgacctca gccagcaact aacccttgct
     7021 agcctaacag aaacactcaa acaagttcaa actagccaag ctgtcagaga caagatcaat
     7081 cttgataaaa ttcttgcttt ctttgacaca gtactcggtc aggaaattct tgctaatacc
     7141 gaccatctct atcgcgagca acctttctcc atgctcaaac gagaccaaaa gagtcaggaa
     7201 gactttgttg tccgtggtat ccttgatggc tatctgcttt acgaaaacaa aattgttctg
     7261 ttcgactaca agacagaccg ctatgatgaa ccaagtcaac tcgtagaccg ctatcgtggt
     7321 cagttagctc tatacgaaga ggctttatca cgagcctatt cgattgaaaa tattgaaaaa
     7381 tacttgattt tactcggtaa agacgaggtt caagttgtaa aagtataact tatactcttt
     7441 gaaaatctct tcaaaccacg tcagcttcgc cttgctgt
//
LOCUS       DAVBOM010000076         7474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBOM010000076 DAVBOM010000000
VERSION     DAVBOM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.077"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            52..693
                     /locus_tag="VQ878_001963"
     CDS             52..693
                     /locus_tag="VQ878_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET3096252.1"
                     /translation="MRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLDAAYIQNGECKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(735..2723)
                     /locus_tag="VQ878_001964"
     CDS             complement(735..2723)
                     /locus_tag="VQ878_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3096253.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2725..3483)
                     /locus_tag="VQ878_001965"
     CDS             complement(2725..3483)
                     /locus_tag="VQ878_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096254.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3911..4102
                     /locus_tag="VQ878_001966"
     CDS             3911..4102
                     /locus_tag="VQ878_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096255.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4456..4728)
                     /locus_tag="VQ878_001967"
     CDS             complement(4456..4728)
                     /locus_tag="VQ878_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3096256.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4787..5236)
                     /locus_tag="VQ878_001968"
     CDS             complement(4787..5236)
                     /locus_tag="VQ878_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET3096257.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            complement(5223..7352)
                     /locus_tag="VQ878_001969"
     CDS             complement(5223..7352)
                     /locus_tag="VQ878_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET3096258.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2210 a         1562 c         1472 g         2230 t
ORIGIN      
        1 tcagaaacaa atcacgaaat cgattcaaat tttgcaggtc gtttaaatat cctgcgcgca
       61 ggtgttcttg gtgctaacga tggaattatt tccattgctg gtgtggttat cggggttgcc
      121 agtgccacga ccaatatctg gattatcttt ttatcaggat ttgcggctat cttagctggt
      181 gccttttcaa tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa
      241 gctgccgttt cgcgagaaaa actcttgtta gaccaagata gggaactagc caaaaaatcc
      301 ctcgatgctg cttatatcca aaatggagaa tgcaaaactt ctgcccaact cttgaccaat
      361 aagatctttc ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat
      421 gaagaattta ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga
      481 agtttgcctc caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctact
      541 gtccttattg tcggtgtggc ccttcttctc actggttaca ctagtgccag acttggaaag
      601 gatccgacta gaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt
      661 accttcctgc tcgaacaact tttcagcatt tagaatacaa gaaatacctc gattttgaag
      721 tcgaggtatc ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa
      781 atcagcacat aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata
      841 gtcgtatcca gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg
      901 agatgtatga aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgttgatg
      961 gtttgcttga tttgcttttg gtccaaacca actttctgca agataataaa gcgttcacgg
     1021 tcttcgtagc cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag
     1081 ataatggata ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagaa
     1141 ctagcatctg ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta
     1201 aattgattga ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca
     1261 tctacattca taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa
     1321 aaggcttgta aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta
     1381 tttggaacat ggttcacaat gaaatcttta ttaaattctt ctttgacaga aaattgatga
     1441 tcatttagag ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc
     1501 tcatttcctg atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat
     1561 accatgaaaa ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg
     1621 gttccttctt gattcgcaac agcaaagtaa gtgtaacgaa gcacttcttt ctctttaatc
     1681 ttataacctt tgtcacttgc aaactggctc aagagtttgt ccaaatcttc tttttcaaca
     1741 ttttgccctg aaaccccaaa atcatgagga tttagaactt ttttaaagga ttctgcggaa
     1801 ttgaaaatgc ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa aatagcgata
     1861 gttgctagtc caactgcatt tttcttcata cggaaaatca agttagaaac agatatgaga
     1921 ttattaggtt ggtaatagta tttcttattt ttctttaaga tttgaaggaa aacggtaatc
     1981 cctgcattga acaaaagata agtaccaaag ataaccagta aaacagctat gaagaaggtt
     2041 gttaaggctg taagaggatc ttttaccgta agggcaagat aatatccaat ccctaaactt
     2101 atggaaccaa gaatagtttg gagaggaagg aagcgacctt ttttctctcc gctagctttc
     2161 tcacgtgaga gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg
     2221 cctaggaaaa tcaaaccgaa gacaagaagt actgtaatga caactttcat ctggaaggta
     2281 gcgaccagtt ccaccttcaa tttcatcagt ttgagtagga aagcgaaaat caacttgtca
     2341 aacaaggctc caataccgat tcctgctcca acagttagaa tcccaaatag cactaactcc
     2401 ttaaaggtca tactgattag atggcgcttc tccaagccta acatgccata tatacccagt
     2461 tccttggaac ggtttttcat gacaaaacta ttggcataga ggacgataat ggctgacgca
     2521 agggtaacga caaacatacc aaatccaagt gttgcttgaa tggtggttcc tccacggatt
     2581 tccgcaatct ttggattgaa ggttagggag taaaagagat aggtgatggt gactgccaag
     2641 agaacagcca gtgcaaaggg atagtagagt ttgcggtttt taatcaagtt cgataccgct
     2701 aacttattgg ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc
     2761 agagatttct tggaacatct gacgttctgt cttctctcca cggtagattt gattgtaaag
     2821 aatgccgtct ttgataaaga gaacacgctt ggccctgcta gcagctgctg ttgagtgggt
     2881 taccatgagg atggtttgcc cacgctcatt gatttcatta aagacatcaa gtaaggctgc
     2941 agatgacttg gaatcaaggg ctcctgttgg ctcgtccgca aggagaattt caggttctgt
     3001 gatgatggcg cgggctactg ctacacgctg tttctgacca ccagaaatct cgtaagggta
     3061 cttctcttgc aattggttga tacccagatt ttcagctgtc atcaccaatt tcttcatcat
     3121 ctccgttata ggtcttcttg acaagacaag cggaagcaag atattgtcct taacagacag
     3181 agtatctagc aagttaaagt cttggaagac aaatcctagc ttttcacgcc ggaaactaga
     3241 agcctgtgaa tttttaatag ttgctgtatc agttccgttt aggtaaacct gcccacgact
     3301 tggtttatcc agcatagcta ggatattgag cagagtggat ttaccagaac cagactcacc
     3361 catgatagca acgtagtcac ccttttctac ggtgaagtga atatccttga gggcctctac
     3421 ttggttgccc tgaaaacgtg ttttataaat tttttgaacg tgttttacat ctaaaagtgt
     3481 catgagaatc tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat
     3541 cccagctgaa cgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt
     3601 tgtttcatga tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc
     3661 ttgccataac ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga
     3721 aatataagca aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat
     3781 aagtgtgaaa aggcttactt tgaaaaggag gaagcgggaa ctaacatttt agtaaggtta
     3841 cctagataac ataccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag
     3901 gtgcgcttta atgaaacaca aagaacatat actcatcgga cttctctatc tgctctctcc
     3961 attcatcggt cagctcttag ttgaacacac acactttatc ggtacagaat ttaccggcac
     4021 tgcttatgtt atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt
     4081 attgtctcag cagcaaaaat agattaaaaa actgagttta aattactgct tttataataa
     4141 aatgaaataa gaacaggaca aatcgatcag gatagtcaaa tcgatttcta acaatgtttt
     4201 agaagtagag gtgtactatt ctagttccaa tccactatag tttgtggatg aagctggcga
     4261 aatattatta atactattca aaaatcaaag tgcaaactat gtcaacttca cattgccgac
     4321 taaattacag cctgtggctg gcttcctagt ttgcactttg atttttattg agtataaaag
     4381 taaaaaagct ttaaatcaag cagtttagac tattgattta aagatttttg cttattccaa
     4441 atcttctgta gaacctcacc aaaaccagcc ttcattgtcg tcaatggctt gggcttcttt
     4501 gcgtttacgt gggcctgttc cgtacatttc tgcttcgatt tcttccttgg taggcatgat
     4561 agaagctagg atgatataga taatcacgcc aagtccaaag tttgcaactg taaaaatggc
     4621 aaacaagaaa cgaactaggg taacatcaaa attccacttg tctgacagac ctgccagaac
     4681 tcctgaaatc atgcgattgc gtctcatttt ataaaattta ctgttcatga tatttcctct
     4741 ttctgctagg ttagacatag tatatcacgg ggaggctcgg ctttcatcag tcctcaggct
     4801 gatttatcag aagcaattta cctcgacaaa gtccacagcg atagcgttgg gtatcaatcc
     4861 tacgcttgcg ctgatacctt tgctggcagg attgacaacg ataaagcttg agtggtttag
     4921 agttactatt gggcaaggat ggtacaaacc ttaatccatc cactgctttc aaaagttcct
     4981 taaaatcccg atccttgtgt tgatagccct tcccttggaa ataaaggtga taatgacaga
     5041 gttcatgtcg gacaattttc ctaaaaacct ccatacccag tttctgataa accttgggat
     5101 taaaatccag atgcccatct ttggggaaaa atcgcccacc tgtcgaacgt agacgcctat
     5161 tccactggac atgatggata aaagctctcc cgaagtcttc tagtgaaacc tgcttgacat
     5221 aatcagtcag tttcatttgg agcgaggagc gacagattaa ctttttcacg ttcagtatca
     5281 attttcttga cccaaacggt caccaaatct ccaactgaca ccacttgact agggtgtttg
     5341 ataaacttgc gactcatatg agaaatatga atcaagccgt cctcgtgaat cccgatatca
     5401 acgaaggcac cgaagtcaac aacgttacgc acaacacctt ctagcttctg acctaccact
     5461 aggtctttga tatctaggac atcttggcga agcacaggtg cgtcaaagga atcacggaaa
     5521 tctcgacctg gtttgagaag atctgcaatg atatctttaa gggtttctgg accgaggtct
     5581 agctcttgag ccatttcctt gactgaaagg gacttgagtt tgctttgggc ttcttcgttt
     5641 aggtctttaa tatctaaacg tttgaagagt tccttaactg cagtgtaatt ctctgggtga
     5701 actcctgtat tatcaaggat attgctactt tcagggatac gaaggaaacc agcagcctgc
     5761 tcaaaggcct tggctcccag acgaggaact ttcttgattt gggcgcgtga agtgattttt
     5821 ccttcttcct cgcggtattt gacaatattt tcagagatag ttttgttgag tccagctacg
     5881 tgtgaaagaa gagctgggct agctgtattg acattgacac caacttggtt aaccactgta
     5941 tcgacaacaa agtccagact ctcagatagt ttcttctgac tgacatcgtg ttggtattga
     6001 ccgacaccaa ttgacttagg atcgattttg accaattccg caagaggatc ttgcaaacga
     6061 cgggcgatag aaatggcaga gcgtttttca acggtcaagt ctggaaactc ctgacgagca
     6121 agttcgctgg cagaatagac agaagcacca ctttcattaa cgataacata gctgacttca
     6181 gggaaatctt tcagaacttc cgctacaaaa gcttcacttt cacgactggc cgttccattt
     6241 ccaatggcaa taatctctac accgtattga ccaattaaat ctgctaaatc tttcttggct
     6301 tcttcgattt gacgagctga tgctggttta acaggataaa taacctgagt tgtcagcatt
     6361 tttcctgttg catccacgac agctaacttg gcacctgtac gaaaggctgg gtcaaatcca
     6421 agaaccacgc gccctttcag tggagcaacc aagaggagat tgcgcagatt gtcagaaaaa
     6481 agttggatag ctccttcttc agctttctca gttaattctg tccgaatacg acgctcgata
     6541 gcaggcaaga cctttttctt aacggattgc tgaacaactt catcaatata agcatttttc
     6601 accttgaaac gagtagcaaa gaaggcaaga atacggtccg tcgcatgttc aaaaccgatc
     6661 ttcaagacac caagtttctc cccacgattg agagccaagg tacgatagcc ttgcatagtt
     6721 ccaactgtct ctgaaaaatc ataataaatc tgaaaaacct gcttttcatc aagactttca
     6781 tccttggctt gagaagtgag tttagagtgt ctcagcactt cctgataagt catagaacgc
     6841 aaggtcacat cttccgataa ggcttcgacc aaaatatcaa ctgcaccggt caaggcttcc
     6901 ttgccagtcg caaatccttc acagacgaac ttttcagctt ctttctctaa gtcaactata
     6961 ttctgcaaaa tcaagcgagc aagaggaaag agtccagctt cacgggcaat ggttgccttg
     7021 gtacgacgct tttccttata aggaagatag agttcttcaa cgtctgctaa tttttcggca
     7081 actaagatag cttcttccaa ttccttggtc aacttacctt gttcttgaat cttagctaag
     7141 acagcttcct tacggtcatt gagatttgtc agacttttat ccaaatcaat aatagcctta
     7201 atcgccacct catccagact accagtcatg tccttgcgat aacgcgcgat aaagggaata
     7261 gtcgcccctt cagctgtcaa acttagaacg gtatcaattt gctttaacgt cactcccaaa
     7321 tcctgagaga ttttttcata ttttttatcc ataaatctat tataccacaa gctggaaggc
     7381 tttctccaat ccttttcata ctcaataaaa atcaaaaagc aaactaggaa gctagccgta
     7441 ggctgctcaa aatactgttt tgaggttgtg gata
//
LOCUS       DAVBOM010000077         7292 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBOM010000077 DAVBOM010000000
VERSION     DAVBOM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.078"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(112..387)
                     /locus_tag="VQ878_001970"
     CDS             complement(112..387)
                     /locus_tag="VQ878_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET3096259.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VQ878_001971"
     CDS             complement(494..1333)
                     /locus_tag="VQ878_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3096260.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VQ878_001972"
     CDS             1475..2323
                     /locus_tag="VQ878_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3096261.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VQ878_001973"
     CDS             complement(2416..3333)
                     /locus_tag="VQ878_001973"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET3096262.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRIIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VQ878_001974"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VQ878_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ878_001975"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ878_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET3096263.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="VQ878_001976"
     CDS             complement(4596..4940)
                     /locus_tag="VQ878_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET3096264.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ878_001977"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ878_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET3096265.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5488..6087)
                     /locus_tag="VQ878_001978"
     CDS             complement(5488..6087)
                     /locus_tag="VQ878_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET3096266.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLF
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6856
                     /locus_tag="VQ878_001979"
     CDS             6557..6856
                     /locus_tag="VQ878_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET3096267.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7075..>7292
                     /locus_tag="VQ878_001980"
     CDS             7075..>7292
                     /locus_tag="VQ878_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3096268.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
BASE COUNT         2335 a         1473 c         1193 g         2291 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgac
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggtat taccctcatc acattttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaaaat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggtgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatt ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattat acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatccgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg atatcaaaac aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcacccctca gctcgccatc ttcggctctc
     4921 tcaaagactg cttgtatcat gtgttctcct taaaattaag cgttaattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa caactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa tgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacaa
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatca
     5461 agctttttct tttacttttt tctgccacta ggcaaaaagc atactgagat aaaaaatgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaaa caggctaaca aatatgaacc cttcacgcaa
     5641 aaaaggagtg tgcttagttc ggaaataatc tccaaaagct agcattgttc gtttgatatt
     5701 ccctgtcata aaggcattat tgtaggcaat acccgaaacc tcaccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggctgcac tagatagata ttatctacag tttgtggcac
     5821 aaaaccaata attattgata ggattgctaa aggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccattataa acgttattaa
     5941 ggttaaaagc ttatccctaa catccgaaac attattttgt attagctcta ccgaaagaaa
     6001 gacaacattt ccagcttgtc cagctacaag ggtattccct cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa atgtcaaaaa agtgctaacc ttttagactg acgtgatatt
     6121 tttcttatag gtaataacct cattttccct cccattgtat tttctcttag aaatattgta
     6181 ccatttcttt ctaaaaaatc gtagactacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acctgggctt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcga ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aggaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaacaaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatactt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc cactatagat attatggagc ctattttatt gtagaaaaaa
     7021 atcccataag atctataatg aaaagcgacc aaacaactca ttagaaagat tcatatggga
     7081 caattacatt ttatcacaaa attactagac attaaagacc ctaatatcca gattttagac
     7141 atcatcaata aggatacaca caaggaaatc atcgccaaac tggactacga cgccccatct
     7201 tgccctgagt gcggaagtca aatgaagaaa tatgactttc aaaaaccgtc taagattcct
     7261 taccttgaga caactggtat gcctactaga at
//
LOCUS       DAVBOM010000078         6839 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBOM010000078 DAVBOM010000000
VERSION     DAVBOM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6839
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.079"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(58..384)
                     /locus_tag="VQ878_001981"
     CDS             complement(58..384)
                     /locus_tag="VQ878_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3096269.1"
                     /translation="MVEYISRKYFLTEEEFQAEKICNQSLVELFQKKYSWHSLNDFGS
                     STYDKNYASIFYEYWRSFLTVDKLVENLGSVQAVLDSYHLWANTEKTFPLLDWFVQQK
                     LIEKEI"
     gene            complement(351..635)
                     /locus_tag="VQ878_001982"
     CDS             complement(351..635)
                     /locus_tag="VQ878_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3096270.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTLISGSKRGWLNILVASIS"
     gene            complement(908..1750)
                     /locus_tag="VQ878_001983"
     CDS             complement(908..1750)
                     /locus_tag="VQ878_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET3096271.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALVWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(1864..3255)
                     /locus_tag="VQ878_001984"
     CDS             complement(1864..3255)
                     /locus_tag="VQ878_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET3096272.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3490..3867)
                     /locus_tag="VQ878_001985"
     CDS             complement(3490..3867)
                     /locus_tag="VQ878_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3096273.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            4082..5059
                     /locus_tag="VQ878_001986"
     CDS             4082..5059
                     /locus_tag="VQ878_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3096274.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLTDKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYKTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5056..6138
                     /locus_tag="VQ878_001987"
     CDS             5056..6138
                     /locus_tag="VQ878_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3096275.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRIGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(6202..6839)
                     /locus_tag="VQ878_001988"
                     /pseudo
     CDS             complement(6202..6839)
                     /locus_tag="VQ878_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2055 a         1497 c         1160 g         2127 t
ORIGIN      
        1 tctgccactg atgcagtgaa atgtcaattt cttagacatt gtttactcct ttagttttta
       61 tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa aagttttttc
      121 tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta aattttctac
      181 caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg catagttctt
      241 atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ctatacttct tctgaaaaag
      301 ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg tcaagaaata
      361 cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt cataaccatt
      421 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
      481 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
      541 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
      601 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
      661 actgaataag caaaagaacc acatctgaca atcctaggtt gatttaacct aggggcgtca
      721 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
      781 cagctcatta ttttgcccta cttggctccc actgtcccaa gctcgcttga agaacgccat
      841 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
      901 tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca gcaatcgttt
      961 ttaaggtttc tctctcctca tgactcagtt caattccaaa gcaatcaaga ttagcttgaa
     1021 tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag ctccagacca
     1081 aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact tgcttgctat
     1141 caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc ttttcacgac
     1201 agtaagctac gacttgttct tgatacacac ctggcgccaa gcgaacttga ttgaccgcag
     1261 gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc
     1321 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
     1381 tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa tgaatcaaat
     1441 acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct tgacgagttt
     1501 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct tcacgtggaa
     1561 ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc gccgccgtat
     1621 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
     1681 ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta tttaattgat
     1741 aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa acatttttta
     1801 agtagtacta tattctgtaa aaaataagtc tgtcaaatat ctaacagacc tattttttct
     1861 tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat tgagcatctc
     1921 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
     1981 attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag ctacttgatg
     2041 ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
     2101 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag caccataagg
     2161 tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct cagtatcagt
     2221 aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc tccaactatg
     2281 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
     2341 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
     2401 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgatg
     2461 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
     2521 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
     2581 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
     2641 gtcagagaag ttttttacaa tctgctcact ctggtcttga tctatttttt tatcctctat
     2701 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
     2761 gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac tggtcttttc
     2821 agtctcttca atcttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
     2881 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
     2941 ttctagcttg tccttaacat cttgatttat cagctcccta acagaggaaa tcactttctc
     3001 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
     3061 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
     3121 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
     3181 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
     3241 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
     3301 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
     3361 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
     3421 agacctatac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
     3481 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
     3541 atcgacaatt gcgatagcgt atactagtgc gatttgtttg tagctctggt gggtatcacc
     3601 ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
     3661 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
     3721 atctaactcc gccaagacgt ctatactagt atagaaatct tgcgctgagt agggcatgga
     3781 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
     3841 catatcgcgg ataaattgac aaatcattag ttgggctgat acctggatgt ctgagaatcc
     3901 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
     3961 ctatctattt attcggaaaa gaaagctaat agcttatttg aaattttctc ctctctgttg
     4021 gatagtcccg tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt
     4081 tatgctaaaa ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc
     4141 ccataccagt ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc
     4201 aacctttgct tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa
     4261 atcttctttt gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa
     4321 agctgccttg tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca
     4381 agaatggttt gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc
     4441 tcgtaattac cacgagaaag cctttactac tatcaaaaac tttttaacag ataagcaagt
     4501 gttaggagca gatttcaact atgccaaata ctcttccaag atgcctgact tgttggctgg
     4561 acaaacacca aatgtctttt cagaccgttt tgctggtgga gccctcatgg atttggggat
     4621 ttatcccctc tatgctgctg ttcgtctttt tgaaaaagct aatgacgcga cttaccatgc
     4681 tcaacagctt gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta
     4741 tcaagttcac atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac
     4801 aacagatgga accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga
     4861 ccaccaagga aatcaagtcc agcttcctat ccaacaggct cctcatacga tgactgagga
     4921 agtcgctgca tttgcacaca tgatccagca accagatctg aatctctaca aaacttggct
     4981 gtatgatgca ggctctgttc atgagctact atataccatg cgccagactg ctggcattag
     5041 atttgaggca gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa
     5101 ctcggtttcc aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga
     5161 gaaaacctcc taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca
     5221 agtcttctca gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaacacg
     5281 gaacttgctg gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact
     5341 gctcaactct tcctttcagg ttcaagtcag aaacgacaaa ttgaacgtct taaaaagggg
     5401 ccagaaattc tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc
     5461 aagatgatga atgtggaaac catcatcctg gatgaatttg accaattact agatgattct
     5521 cagattcact ttgtagaaaa aatcactcac tacgcacctc gtgaccacca actggtctac
     5581 atgagtgcca cgaccaagtt tgaccaagaa aagattgtgc cgaatacacg cactattgat
     5641 ctctctgacc aaaaattgga caatatccag catttctaca tgcaggtaga ccaacgtcat
     5701 cgagtggata tgctacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc
     5761 aatagcctgt cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattgact
     5821 gtttccctcg ctagtgatgt taatgttaaa tttagaaaaa tcatcttaga aaagtttaaa
     5881 gataaccaac taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat
     5941 agcctagaat gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt
     6001 gctggtcgta ctggccgtat aggcaaggaa ggatatgtta ttactctcgt cactcatcca
     6061 gaagaaatca aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa
     6121 gaactctata tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt
     6181 ataagcaatt caattttata ctcatctgct ttcaaaaagc attctattcc atctccgatt
     6241 aacgatggac tttatcacct ccttctccag tccttgtatg acatcttgga gttgattcat
     6301 gacatcttcc aaagttcgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca
     6361 cacttgttca atgggttcat ctctggtgtg tatggaggaa taaaggtaaa atcaatatta
     6421 gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaaa
     6481 taatcatctg gataagcttg tgaaagctct tctaaaaagg cgttcatcca ctcagtatta
     6541 catccaccag ctattaagaa aaatgattcg cctgtatggg catcaacagc tccataacaa
     6601 tagcgaaatt ctcgtatata gtgactatgg acatgtggac ctactcctat tggagaccaa
     6661 caagatccca gtttactgat tctaccgaaa ccagcctcat cttggtacat caagcgaacc
     6721 ttatgaaaag gtctactggt tttaaagcgc tttcttgtct tcttgaattg agattttatt
     6781 tttagacgcg acaatggttt gagcgtctgc tttcttagga tgttctggac gtggcgtaa
//
LOCUS       DAVBOM010000079         6726 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBOM010000079 DAVBOM010000000
VERSION     DAVBOM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.080"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            138..860
                     /locus_tag="VQ878_001989"
     CDS             138..860
                     /locus_tag="VQ878_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3096276.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1077..2411
                     /gene="pepC"
                     /locus_tag="VQ878_001990"
     CDS             1077..2411
                     /gene="pepC"
                     /locus_tag="VQ878_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET3096277.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2467..3378)
                     /locus_tag="VQ878_001991"
     CDS             complement(2467..3378)
                     /locus_tag="VQ878_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3096278.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3402..4205)
                     /locus_tag="VQ878_001992"
     CDS             complement(3402..4205)
                     /locus_tag="VQ878_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET3096279.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ878_001993"
     CDS             complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ878_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET3096280.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ878_001994"
     CDS             complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ878_001994"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET3096281.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKI
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2017 a         1388 c         1478 g         1843 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg cgacgttgac gcggtttgaa
       61 gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc ctccttttga
      121 tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg gtgggaagtc
      181 ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa
      241 aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt
      301 tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt atctcagcga
      361 ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg cggagtaagg
      421 aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc ttgaccaatg
      481 atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag acttatctgg
      541 cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag ggtattcctc
      601 tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat acagaaaaga
      661 atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc aagcgtatgg
      721 tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga actttagtat
      781 tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa ttagaaattc
      841 tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga gcaaactagg
      901 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat
      961 tttcgaagag tataaattcg aaaaaggtga gggacaatgt cctcgccttt tatgtttttt
     1021 agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag gaatctatga
     1081 acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca aatgtaaaat
     1141 accaagcgat tgaaaatgct gccagccaca acggaatttt tgcagctctg gaacgtcgcc
     1201 aaagccgtgt agacaacaca cctgttttct cattggattt aaccaaggac aaggtcacta
     1261 accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc cgccacaaac
     1321 tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact ttcttctggg
     1381 ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca gaccaagaat
     1441 tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggc ggtcaatggg
     1501 atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt
     1561 ctgtttcatc tagcagcagt cgtgagctaa atgcggtcct taataaattg cttcgtcaag
     1621 atgctcaaat cttgcgtgat ttgcttgttt ctggtgcaga tcaagtgact gttcaagcta
     1681 agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta ggacttccac
     1741 cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt gaaaaaggaa
     1801 tcacaccaca agagttctac aagaaatatg tcaatcttcc tttagaagac tacgtttctg
     1861 ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt gagatgttgg
     1921 ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag cgcttgaaag
     1981 aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct gatgtcggcc
     2041 agctcagtaa ccgtaaggct ggaatccttg cgacagatgt ttatgacttt gaatcaagca
     2101 tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa agcttgatga
     2161 cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca accaagtgga
     2221 aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt gcctcagacg
     2281 cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg acagcagaag
     2341 aacaagctgc ctatggagca gaaccaattg tacttgcacc atgggatcca atgggagcct
     2401 tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc ctttttagtt
     2461 gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga gagcaaggat
     2521 aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag taaggagtag
     2581 tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa ctttttcagg
     2641 agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt tagacccttc
     2701 tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag aaacatcgaa
     2761 agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca tcccaaggat
     2821 agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag tgatttctga
     2881 tccagcctta tatccaatct cttgaacata ccacaagaat gacatacgaa tcaagttcca
     2941 tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg aagcaccgag
     3001 agatccaagg attgggcgca ctgtaaacca gaatactggg tcaccgatac cagcaagagg
     3061 tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca caccgttagc
     3121 acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt atggatgagt
     3181 gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt tagtatagag
     3241 ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt
     3301 ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg atttagttaa
     3361 ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc ttctaggata
     3421 tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc agttttagaa
     3481 aggtgaaggt agataagagc gatagcaacg ccgatagcac cgaatccgat tagagtaata
     3541 tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc acgagttgcc
     3601 atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc gatagccata
     3661 ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc agttggtacc
     3721 ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag cgcgatgaaa
     3781 tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc agtatgaacc
     3841 aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac agcaagaggg
     3901 atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc aagaaccatg
     3961 ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc accgatattt
     4021 gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc ttccaagtga
     4081 cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg gaactggtcg
     4141 aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat agaaataata
     4201 gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt gttaatcaag
     4261 tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc aacacccaag
     4321 tcacgcattt tttcaaatgt agcaacgtct tctttgtcca tagacaaaac ggtattgacc
     4381 aatgttttac ctgttgagtg agccatagaa ccaacattaa gagtcttgat tggcacgccg
     4441 ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc atgtgtttct
     4501 ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac gttagccttg
     4561 acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt agccacgtta
     4621 tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt tgcaacctga
     4681 ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc gtctccgata
     4741 acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct tgcaacttct
     4801 tcgactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc tttaatgata
     4861 ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt gtaggcttga
     4921 atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg attttctccc
     4981 atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa aactagaacc
     5041 tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag atcatcagga
     5101 ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa gatcatagat
     5161 cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat tccgatactc
     5221 attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt aagactgttt
     5281 aagtataaac cgttttcata aaaaaagcaa ctatttatca taaaaaatta aaaaattttt
     5341 atttttgtat gttgatatgt tgagtttttg aggagtaatc ttgaattctt atttaaaatt
     5401 taatataaaa aagttggaag aagcttccaa cttttaaaat aggtttctat tagattagtg
     5461 ggtgaagtcg agtaccatac gtccttggat ttggcctttt tccatttcgt cgaaaatggc
     5521 aacagcatct tctactggac gtttttgaac aactgggact accagacctt ctgcaccaaa
     5581 ttggaaggct tcttctaagt ctttacgagt tccgacaaga gaaccgatga cttggattcc
     5641 atcgaggact gttttaacga tgctgagttc catcatttca gaaggaagac caacagcgac
     5701 gacgcgacca ccagcacgaa tggagtcaac agcctggttg aaggcaactt tagacacagc
     5761 agttacgaca gctgaatgag ctcctccatc agttttttct ttaatgagtc cagctacatc
     5821 ttcaacttcg aggccgttaa tcacaatgtc agcgcctact tcttttgcaa gggcaagttt
     5881 gtcattgttg atatcgactg cgataacatg agcattgaat acttttttag cgtattgaac
     5941 agcgaggtta ccaagtccac cagcaccgta aagaacaacc cattggcctg gttcaatttt
     6001 tgcttctttg atagctttat aggttgttac tccagcacat gtgatagaag aagcttgggc
     6061 tggatcaagt ccgtcaggaa ctttgacagc atagtcagca gttacgatac attgttcagc
     6121 cataccaccg tctactgagt agccagcatt tttcactgta cggcaaaggg tttcgcgacc
     6181 agttgtacag tattcgcaag tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc
     6241 accgacttta aggcttttca catctggagc aatctcttta acgataccga taccttcgtg
     6301 cccaagaaca cgtcctggga cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg
     6361 gcaaacacca cagtattcaa cttctacaag tgcttcccca gtttcaagtg gacggagtac
     6421 tttttcttca atagcaacac cagtgctttc tggatttaca acaacagctt tcatagctat
     6481 cctccttgat attgaccgag aacagggaca acgggactgg attgattttt tgtcaacaga
     6541 gtcgagtgtg acgagctctc ttgtatttat atgtgaagta tatcacaaaa gaaagccttt
     6601 tccaaggttt tggagacaaa aagtagaaca atcgattaac tggttgatga gactgtgaaa
     6661 agagcacaaa gaccagcttg caagctggtc atactcttcg aaaatctctt caaaccacgt
     6721 cagctt
//
LOCUS       DAVBOM010000080         6632 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBOM010000080 DAVBOM010000000
VERSION     DAVBOM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.081"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..218
                     /locus_tag="VQ878_001995"
     CDS             <1..218
                     /locus_tag="VQ878_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3096282.1"
                     /translation="VIIMDNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWA
                     HIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            279..1241
                     /locus_tag="VQ878_001996"
     CDS             279..1241
                     /locus_tag="VQ878_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3096283.1"
                     /translation="MNMSNITIDGQEIDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMFGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1419..2426
                     /gene="gap"
                     /locus_tag="VQ878_001997"
     CDS             1419..2426
                     /gene="gap"
                     /locus_tag="VQ878_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET3096284.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2493..3329)
                     /locus_tag="VQ878_001998"
     CDS             complement(2493..3329)
                     /locus_tag="VQ878_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3096285.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3455..5650
                     /locus_tag="VQ878_001999"
     CDS             3455..5650
                     /locus_tag="VQ878_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3096286.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVDLTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5703..5855
                     /gene="rpmG"
                     /locus_tag="VQ878_002000"
     CDS             5703..5855
                     /gene="rpmG"
                     /locus_tag="VQ878_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3096287.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5865..6041
                     /gene="secE"
                     /locus_tag="VQ878_002001"
     CDS             5865..6041
                     /gene="secE"
                     /locus_tag="VQ878_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET3096288.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6096..6632
                     /gene="nusG"
                     /locus_tag="VQ878_002002"
     CDS             6096..6632
                     /gene="nusG"
                     /locus_tag="VQ878_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET3096289.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2062 a         1161 c         1431 g         1978 t
ORIGIN      
        1 cggttattat tatggataat gtaagattcc atagaatggg gaagctagaa cttttatgcg
       61 aagagtttgg gcataaactg ttacctcttc ctccctactc acctgagtac aatcctattg
      121 agaaaacatg ggctcatatc aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct
      181 tttacgaggc ttttttatcc tgctcttgtt tcaattgact atatatcacg gatacagttg
      241 ggaaagaagc tattaaatat ttggagagtc cttttgggat gaacatgtca aatattacta
      301 tagatgggca agaaatagat ctgagtcaaa cgatgccttc ttatgctcaa gtagtgagtc
      361 tttatgatga tacaagtatc tctgttagta gtaatgagac ggacaaagtg ttggctggat
      421 ccctctatac tgatacaaat gaacagggat taacgattcc aagcagttta ctaaaaaatt
      481 ggaatgaaca gacaggaaaa aatttgacag ctaatgatct tattggcaaa tcagtctcag
      541 ccagcattgt agaaagtgct gccgaaacta gtaagattgc tcaatttcaa acgaagattg
      601 tacgtgtaat caatgatgaa gatgacatgg aggacagcaa cagtttcatg ctgtctcatc
      661 aaatggaaac gattttgaaa gaggctggat ttacgaaagc tgtatcttat tttatcttgg
      721 aactcaaaga tccatcacag acaaaagtag taacagaaga attacagaaa aataagaagt
      781 atactgtgct ttctcaacag agagttcttg atattgtgat tacctttatt cgtgttattc
      841 agggattatt gattgtgctt tcatcacaag ctattgtggt agcagcggtt atgtttggta
      901 tcattattta catcaatatc atgcaacgtt ctaaggaaat aggtgtcatg aaggcagttg
      961 gttatcagaa tcgtgatgtc aaaggaattt ttatttacga ggctatctgg attgtaggca
     1021 tcgccttgct gctggcattt ttggttgcac aaggggtggg aagtttggcg aatgcgattg
     1081 taagtcactt ttacccatcc atcactaagg tttttgaatt aaatctttta tctgttttag
     1141 gaactctagt tttcgctcta ttacttggtt atgtctcagc ctacttcccg gcgcgtaaga
     1201 ttagtaaaat ggatcctgta gaaccgttac gctatgaata gtaagggatt ccttgattta
     1261 cagtcttaaa aaagaaacta acatagaaaa acaatggcca tacttgcaat tcaactcaaa
     1321 tagttgtata ataggtttgt tgaaaggtga tttgtagtga ttcaagttac tcttttcaca
     1381 ataaaaattt catgattttc ataaggagga aatcactaat ggtagttaaa gttggtatta
     1441 acggtttcgg acgtatcggt cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg
     1501 aagttacacg catcaacgac cttacagatc cagttatgct tgcacacttg ttgaaatacg
     1561 acacaactca aggtcgtttc gacggtactg ttgaagttaa agaaggtgga tttgaagtta
     1621 acggtaaatt cgttaaagtt tctgctgaac gtgatccaga gcaaatcgac tgggctactg
     1681 acggtgtaga aatcgttctt gaagctactg gtttctttgc taagaaagaa gcagctgaaa
     1741 aacaccttaa aggtggagct aaaaaagttg ttatcactgc tcctggtgga aacgacgtta
     1801 aaacagttgt attcaacact aaccacgacg ttcttgacgg tactgaaaca gttatctcag
     1861 gtgcttcatg tactacaaac tgcttggctc caatggctaa agctcttcaa gataactttg
     1921 gtgttgttga aggattgatg actactatcc acgcttacac tggtgaccaa atgatccttg
     1981 acggaccaca ccgtggtggt gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc
     2041 ctaactcaac tggtgctgct aaagctatcg gtcttgtaat cccagaattg aacggtaaac
     2101 ttgacggatc tgcacaacgc gttccaactc caactggatc agttactgaa ttggtagcag
     2161 ttcttgaaaa gaacgttact gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg
     2221 aatcatacgg ttacacagaa gatccaatcg tatcttcaga tatcgtaggt atgtcttacg
     2281 gttcattgtt tgacgcaact caaactaaag ttcttgacgt tgacggtaaa caattggtta
     2341 aagttgtatc atggtacgac aacgaaatgt catacactgc acaacttgtt cgtactcttg
     2401 aatacttcgc aaaaattgct aaataattct tgagttgata gaaagcaagg ctttgtggtc
     2461 ttgcttttta tatagaaaaa tggatgacac gatcatccat tcttttttaa ttctttttca
     2521 aatgtatttg aaagggtagt gaaagttagc ctctctaaag taagtgggtg ggtaaaggaa
     2581 agtcggaagg catgaagcat aagccggctt gtctttgatt tactattata gagagggtct
     2641 cccaggatag gaagattatg atgcaaaagg tgcacacgaa tctgatgggt tcgccctgtc
     2701 tttagcttgc aatgagccaa ggaagtcttg tttgagaatt gctttaatct gcttacatgc
     2761 gtttcagcat attgcccatt ttttgcatca actattcttt ttctacgatc atggcgatca
     2821 cgtccaattt tgtctctgaa aacaagttct tttctgttga tatttccatc aactagagcc
     2881 caatattctc tagaaatctc ttttttctcc aataagcgat tgagaatggg caggataaaa
     2941 ggatttttgg caaagagaac taagccactg gtttccatgt ccagacgatg aacgacatag
     3001 caggtttggc caacataggt actgacatgg ttaagaaggg caatttcgtt tggttgatta
     3061 ccatgcgttt tcatcccctc tggtttgttt acaataatca agtgttgatc ttgataaact
     3121 tcctgcacta agtctgggtt gccccaaggg atcgtctttt ggggataatc ttcctcgtca
     3181 aaagtcaact ggcaaacatc tccaggattt acgatttcgt tccagtggac ttcttcttga
     3241 tttatcaaaa tatgtttctt gattctcaaa aaatgacgga tttttctagg gatgaggagt
     3301 tgttcctcaa gtaattgctt taccgtcatt tgaggtatag aggcgggtaa tgtaaatgtg
     3361 aattgcatac agatattgta acaaaaaaag ccctatttgg ataggaaata gctaaattct
     3421 tgtcttccta tgatgaagat gataaaataa acgcatgaaa ttagataaat tatttgagaa
     3481 atttctttct ctttttaaaa aagaaacaag tgaactagag gactctgatt ctactatctt
     3541 acgtcgctct cgtagtgatc gaaaaaaatt agcccaagta ggtccgattc gaaaattctg
     3601 gcgtcgttat catctaacaa agattatcct tatactaggt ttgagtgcag gcttgctagt
     3661 tggaatctat ttgtttgctg tagccaagtc gaccaatgtc aatgatttgc aaaatgcctt
     3721 gaaaactcgg actcttattt ttgaccgtga agaaaaagag gctggtgcct tgtctggtca
     3781 aaagggaacc tatgttgatc tgactgatat cagtaaaaac ttgcagaatg ctgttattgc
     3841 gacagaagac cgttctttct ataaaaatga cgggattaac tatggccgtt tcttcttggc
     3901 tattgtcact gctggacgtt caggtggtgg ctctaccatt acccaacagc tggctaaaaa
     3961 cgcctattta tcacaggatc aaactgttga gagaaaagcg aaagaatttt tccttgcctt
     4021 agaattaagc aaaaaatata gtaaggagca aattctaacc atgtacctta acaacgctta
     4081 ttttggaaat ggtgtgtggg gtgtagaaga tgcgagtaag aaatactttg gagtttctgc
     4141 atcagaagtg agtctggatc aagctgcgac tctggcaggg atgctcaagg ggccggaact
     4201 gtataatccc ttgaattccg tagaagattc tactaatcgg cgcgatactg tcttgcagaa
     4261 tatggttgca gcaggatata ttgataaaaa ccaagaaacc gaagctgctg aagttgatat
     4321 gacttcgcaa ttgcacgata agtatgaagg aaaaatctca gattaccgtt acccctctta
     4381 ttttgatgcg gtggttaatg aagctgtttc caagtataat ctaacagagg aagagattgt
     4441 caataatggc taccgcattt acacagagct ggaccaaaac taccaagcaa atatgcagat
     4501 tgtttatgaa aacacatcgc tatttccgag ggcagaggat ggaacgtttg ctcaatcagg
     4561 aagtgtagct ctcgaaccga aaacaggggg agttcgtgga gttgtcggtc aagttgctga
     4621 caatgataaa actggattcc ggaatttcaa ctatgcaacc caatcaaagc gtagtcctgg
     4681 ttctacaatt aagcctttag ttgtttatac gccagcagtt gaagcaggct gggctttgaa
     4741 taagcagttg gataaccata ccatgcagta tgacagctat aaggttgata actatgcagg
     4801 gatcaaaacg agtcgagaag ttcctatgta tcaagccttg gcagaatcgc ttaatctacc
     4861 tgctgttgcc actgttaatg atttgggtgt cgacaaggct tttgaggcag gcgaaaaatt
     4921 cggactcaac atggaaaagg tcgaccgtgt tcttggtgtc gccttgggaa gcggtgttga
     4981 aaccaaccct cttcaaatgg ctcaagcata cgctgccttt gcaaatgaag gtttaatgcc
     5041 tgaagctcat tttattagta gaattgaaaa tgctagtgga caagttattg cgaatcataa
     5101 aaattcacaa aaacgggtga ttgataagtc tgtagctgac aagatgacca gtatgatgtt
     5161 ggggactttc accaacggta ccggtattag ttcatcgcct gcagactatg tcatggcagg
     5221 gaaaactgga acaactgaag cagttttcaa tccggagtac acaagtgacc agtgggtaat
     5281 tggttatact ccggatgtag tgattagcca ctggcttggc tttccgacca ctgatgaaaa
     5341 tcactatcta gctggctcta cttcaaacgg tgcagctcat gtctttagaa acattgccaa
     5401 taccatttta ccttatacgc caggaagtac ctttacggtt gaaaatgctt ataagcaaaa
     5461 tggaattgca ccagccaata caaaaagaca agtacaaacc aatgataata gccagacaga
     5521 tgataatttg tctgatattc gagggcgtgc gcaaagtcta gtagatgagg ctagccgggc
     5581 tatctcagat gcgaagatta aggaaaaggc tcaaacaata tgggattcga tagtcaatct
     5641 atttcgctaa gatgcttgtc aaagcctagc tttcttgtta taatggataa gatggaggcg
     5701 ttatggcact aaaaaaagca agcctagctt gtgcggtttg tggttcgaga aactattcaa
     5761 tcaagatcag cggaaacccc aagcctacac gactagaagt aaataaattt tgtaagcatt
     5821 gtggcaagta cactacacac agagaaacga gataggagag agcgatgcgt tttattggag
     5881 atatttttag acttcttaaa gacacaacat ggccaactcg caaggaaagc tggagagatt
     5941 ttcgttctat catggaatac acagctttct ttgtagtaat tatttacatt tttgaccagt
     6001 tgattgtttc aggtttgatt cgatttatta acatttttta gaagattagt ggagttaatt
     6061 acactagaaa tcttctattt atgaaaggaa atatcatgga tagttttgat aaaggatggt
     6121 ttgttttaca aacttattct ggttatgaaa ataaggtgaa agaaaatcta ttacaacgtg
     6181 cacaaaccta caatatgttg gataatattc tacgcgttga aattccaaca caaacagtgc
     6241 aagttgaaaa aaatggaaag agaaaagaag tagaagaaaa tcgctttcca ggttatgttc
     6301 ttgtagaaat ggtcatgaca gatgaagctt ggtttgttgt tcgaaacaca ccaaatgtta
     6361 caggatttgt cggatcacac gggaacagat caaaaccaac tccattattg gaacaagaaa
     6421 ttcgtgacat tttggtatct atgggacaaa ctgttcaaga atttgatttc gatgttgaga
     6481 ttggtcaaac tgtacgtatt attgatggtg cttttgcaga ctacactggt aagattacag
     6541 aaattgataa taacaaagtg aaaatgatta tctctatgtt tggtaatgac acagttgcag
     6601 aagtaaacct aaaccaaatc gcagaattat aa
//
LOCUS       DAVBOM010000081         6627 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBOM010000081 DAVBOM010000000
VERSION     DAVBOM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.082"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VQ878_002003"
     CDS             170..370
                     /locus_tag="VQ878_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096290.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDQK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            412..816
                     /locus_tag="VQ878_002004"
     CDS             412..816
                     /locus_tag="VQ878_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096291.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ878_002005"
     CDS             1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ878_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3096292.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ878_002006"
     CDS             1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ878_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET3096293.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDASNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAETAFKEMN"
     gene            2697..4088
                     /locus_tag="VQ878_002007"
     CDS             2697..4088
                     /locus_tag="VQ878_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET3096294.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIIAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ878_002008"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ878_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET3096295.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ878_002009"
     CDS             5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ878_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3096296.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT         2032 a         1215 c         1411 g         1969 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatatc ataactgttc ctagtcaacc
      121 tgcaagccct atcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagctag accaacgctt gaaagctttg gcaacagtat ctgatcagaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgggctgc cttggactct
      421 ctcaaagatg tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca
      481 aaacaaggaa cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg
      541 gcaggagtga ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt
      601 cgccgtaaga aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga
      661 cagctagatg cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa
      721 gaaacccttg atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta
      781 gaggagctta aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac
      841 ctaaaagaca ttttcgttca caaaagcagc gatgagtaat ccttgtcgtt gctttttggc
      901 tattttgggg gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc
      961 gatacgattt tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta
     1021 gaattattaa gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc
     1081 tagcaggtgt tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg
     1141 ggattttatt ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc
     1201 tctggtcagg cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta
     1261 ttctaggctt tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg
     1321 gcatgggagc tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga
     1381 aattagaagt tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag
     1441 cttttttact tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa
     1501 gttctgtttt agcacttgcg gcttctggag gcaatggcgc ttggcaagga gcgatttata
     1561 ctctcattta cactctgggc atggcccttc ctttcttggt attggcacta gcttcaggtc
     1621 tagtcatgcc atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg
     1681 gtttcctcat tgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg
     1741 gaatttttga ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg
     1801 tcattagttg tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa
     1861 cagccaaaac aacaaacgac tgtacaacaa attgctgttg gaaaagatgc ttcaaacttc
     1921 acattgcaat ccatggatgg caaagaagtt aagttatctg attttaaggg taaaaaggtt
     1981 tacttgaagt tttgggcttc atggtgcggt ccatgcaaga aaagtatgcc agagttgatg
     2041 gaactagcgg cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt
     2101 caaggtgaaa aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat
     2161 atcccagttc tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagcatt
     2221 cctacagaat atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc
     2281 agtaatgcgg atgcagaaac agcatttaaa gaaatgaact agaatcgata aaatctgatt
     2341 acaagatgta gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag
     2401 cttttagtat gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact
     2461 ggttttcttt ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtttta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtc tttacaatca
     2821 caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagccct tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agtactggta
     3361 ttatagctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga tggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccgc tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc ctgctggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgattca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcagaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa
     4921 ccaagtccac gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg
     4981 atttttacag aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta
     5101 gaaaatctgg aagaaaatat gagtgttcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aatcaataaa aaatatgtag caggttcagt ggcagttctt gccctaagtg tttgttccta
     5221 tgaacttggg cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 caccacagat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
     5761 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
     5821 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
     5881 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
     5941 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
     6001 tgctaaaccc ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca
     6061 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     6121 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     6181 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aaccgactcc
     6241 agaacctagt ccaagtccgc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6301 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6361 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     6421 gcaggaaagt ttatctcata agctaggagc taagaaaacc gacctcccat ctagtgatag
     6481 agaattttac aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa
     6541 taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac tcaaggatgt
     6601 ctcaagtgat aaagtcaagt tagtgga
//
LOCUS       DAVBOM010000082         6206 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBOM010000082 DAVBOM010000000
VERSION     DAVBOM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.083"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(482..707)
                     /locus_tag="VQ878_002010"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VQ878_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VQ878_002011"
     CDS             1555..2427
                     /locus_tag="VQ878_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET3096297.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VQ878_002012"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VQ878_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3372
                     /locus_tag="VQ878_002013"
                     /pseudo
     CDS             3060..3372
                     /locus_tag="VQ878_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3376..4092
                     /locus_tag="VQ878_002014"
     CDS             3376..4092
                     /locus_tag="VQ878_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3096298.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4222..5037)
                     /locus_tag="VQ878_002015"
     CDS             complement(4222..5037)
                     /locus_tag="VQ878_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET3096299.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5034..5939)
                     /locus_tag="VQ878_002016"
     CDS             complement(5034..5939)
                     /locus_tag="VQ878_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET3096300.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         1961 a         1073 c         1249 g         1923 t
ORIGIN      
        1 aaataagata tgtacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagtaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aattcacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgatagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatatttttc gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggt acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata ccaaaaacag
     2701 ccgcaatttg ttcataagtg cgatattctc gcacttattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taacatctct ttaaaagtcg tgcgttgaac accaacaaga cgcttaaatc
     2881 gtgcatcggt tagttgttta cttgcttcat aattcataga actattatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct gttattcaga agagaacttg
     4201 ttcgttttta tcttgatttt cttaaaaagc tctatataca tagggatttt ctggtttatc
     4261 gactttggta aagctgtcga tttccaaggt tggaaggttt tgtttgagtt ctttatggta
     4321 gtgattgacc agttttcctt tggctgaaat ccaagtgttg ttttcatact gccgggtatt
     4381 gcccttggtc agcaatccat agacaccaga atctgcgatg cagtgaataa tgccgaagcg
     4441 gaacagaaat tggctattgg catgactggg gtcattatag acaaagcctg tgaactggat
     4501 tgtcttaccc tcaaattcat ctggatagtc gtagatagcc tccatgacct ccatatagtt
     4561 ttcattagtg atctgaatac tatcttggga taagtattta tccgccgccg ttcgcatttc
     4621 cttttcatag gctgattttg aaaaataaga actggtatct ggtttcaaat attggcttgt
     4681 cgtcccttcg cttgtctgaa tggctagatc cgttccttcc gataggggga aatgataacc
     4741 tttagcagaa acggtctgag aatccaagct aacagttggg aaagttaagc cgatgacaag
     4801 tggaatagcc agaagagaaa tactcgtcat cttggctaat cggctgttca gatgactgtg
     4861 ggttttgact tgcttcatcc agatatacaa ttgaacgata gccaagataa aagaaagcac
     4921 catggagata taggccagat aggaatagtg catgttgatg tactggttta gtttgcccga
     4981 cagatggagg taaatagtca gttcaaaata gccagctaaa actaaaaatc gaatcatagg
     5041 atgactccaa tcaagagaga atagactaag acgacaagag ttacaattgt tatgaagtga
     5101 ctgataaatc gtgctttcaa gtaatttttc atcatgagaa tatttttgat atccagcatt
     5161 ggaccaatga cgagaaaggc cagaactggt gccaaaccga aactcgagag aagagaagca
     5221 cctataaagg catccgcctc actacagagc gaaagaagaa aggctaaaat catcaagagc
     5281 aggatggcaa aaagaggggt cgcactgata gaggtcagaa tccgagtcgg aacgtagacc
     5341 tgtattatag aagcaaagag gcagccaaat accaaataac gccccgtatc aaaaaattca
     5401 tcaatggcct gcacaaagac ttgaaaaact ttttttgcag aactcaagta agaaaaatca
     5461 tgctcatgac aagccagacg attttctttc tgaatcggtt cttgccagaa aaatcctaga
     5521 aaaattccta gtattacagc cacaagaatg gaacccagag ctcgtaatag ggcgacatgg
     5581 aaggagttgc caaaggcaga ataggtcgca aaaagaacaa tgggattgat aacaggtgct
     5641 gtcacaagaa aaggaacggc cgtgtaactt ggaacctttt tttccagaaa acgattgatg
     5701 atggggacga ttccacattc acaagaaggg aaaaacatac cgacgaaggt cccaaaaaag
     5761 attctccccc aacgatttcg agggagaaaa tgataaacct tgtcaggtgt gatataaact
     5821 tcaatcagcc ctgagacaat gcttcctatc agaacgaagg gaagggcttc aatgataatg
     5881 gagagaaaaa tggctccagt ttgaagtaca ctagatggga gttgttgaaa agcagtcatc
     5941 tagtttttct tttctgcttt ggcttttttc tctttgtcat cagggaaagt aacttgtttc
     6001 aaatcaggga gtttagcaaa ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat
     6061 tttacagcca taggtgtacc tcgattctaa attctacctc tattatacta ttattttgcg
     6121 gaaaagggag ttttttaatt tgttttcgat agttgatact cttcgaaaat ctcttcaaac
     6181 cacgtcagct tcgccttacc gtagta
//
LOCUS       DAVBOM010000083         5511 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBOM010000083 DAVBOM010000000
VERSION     DAVBOM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.084"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            80..718
                     /locus_tag="VQ878_002017"
     CDS             80..718
                     /locus_tag="VQ878_002017"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET3096301.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            715..1605
                     /locus_tag="VQ878_002018"
     CDS             715..1605
                     /locus_tag="VQ878_002018"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET3096302.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            1645..1962
                     /gene="yabA"
                     /locus_tag="VQ878_002019"
     CDS             1645..1962
                     /gene="yabA"
                     /locus_tag="VQ878_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET3096303.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            1965..2834
                     /gene="rsmI"
                     /locus_tag="VQ878_002020"
     CDS             1965..2834
                     /gene="rsmI"
                     /locus_tag="VQ878_002020"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET3096304.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESSHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            3061..3579
                     /locus_tag="VQ878_002021"
     CDS             3061..3579
                     /locus_tag="VQ878_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET3096305.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            3688..4335
                     /locus_tag="VQ878_002022"
     CDS             3688..4335
                     /locus_tag="VQ878_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3096306.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(4324..5129)
                     /locus_tag="VQ878_002023"
                     /pseudo
     CDS             complement(4324..5129)
                     /locus_tag="VQ878_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            5124..5378
                     /locus_tag="VQ878_002024"
     CDS             5124..5378
                     /locus_tag="VQ878_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3096307.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGEHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT         1796 a          913 c         1214 g         1588 t
ORIGIN      
        1 aaatgagaag acaaaaagat tgtcacaaac ccctattttt ttgatagaat agaagtagta
       61 aaaaagaaat gagttagaca tgtcaaaagg atttttagtc tctcttgagg gaccagaggg
      121 agcaggcaag accagtgttt tagaggctct gctaccaatt ttagaggaaa aaggagtaaa
      181 ggtgctgacg acccgtgaac ctggcggagt cttgattggg gagaagattc gggaagtgat
      241 tttggatcca agtcatactc agatggatgc taaaacagag ctacttctct atattgccag
      301 tcgcagacag catttggtgg aaaaagttct tccagccctt gaagctggca agttggtcat
      361 catggatcgt tttatcgata gttctgttgc ctatcaggga tttggtcgtg gcttagatat
      421 tgaagccatt gactggctca atcagtttgc gacagatggc ctcaaacccg atttgacact
      481 ctattttgac atcgaggtgg aagaagggct ggctcgtatt gctgctaata gtgaccgcga
      541 ggttaatcgt ttggatttgg aagggttgga cttgcataaa aaagttcgtc aaggctacct
      601 ttctcttctg gataaagagg gaaatcgcat tgtcaagatt gatgctagtc tccctttgga
      661 gcaagttgtg gaaactacca aggctgtctt gtttgacgga atgggcttgg ccaaatgaaa
      721 caagatcaac taaaggcttg gcaaccagct cagtttgacc gttttgtccg tatcttagaa
      781 caagaccagc tcaatcacgc ctatctcttt tcaggtttct ttggaagctt ggaaatagcg
      841 caatttttag ctaagagcct cttttgtacg gataaagttg gcgtcttacc atgtgagaaa
      901 tgccgaagtt gcaagctgat tgaacaggga gaatttcccg atgtcacctt gattaagcca
      961 gtcaatcagg tcatcaagac agaacgcatt agggaattgg tgggacagtt ttctcaagca
     1021 gggattgaaa gccagcaaca ggtctttatc atcgagcaag cggataaaat gcatcccaac
     1081 gcagccaatt ctctgctcaa ggtcatcgaa gaaccccaga gtgaagttta tattttcttc
     1141 ttgactagcg atgaggaaaa gatgttaccg acaatccgaa gtcggaccca gatcttccac
     1201 tttaaaaagc aagaagaaaa acttatctta ctcttagaac aaatgggact tgttaagaaa
     1261 aaagcgactc ttttagctaa gtttagtcaa tcgcgagctg aagcagaaaa gttggctaat
     1321 caggcaagtt tttggacctt ggtcgatgaa agtgaacgcc tgctgacttg gttagtagct
     1381 aagaaaaaag aaagttatct acaggttgcc aaattagcca acttggcaga tgataaggaa
     1441 aaacaggatc aggttttacg gattcttgaa gttctctgtg ggcaggacct cttgcaggta
     1501 agagtaagag tgattctaca agatttacta gaagctagaa aaatgtggca agctaatgtc
     1561 agctttcaaa atgccatgga atatctggtc ttgaaagaaa tataaactca aaaatgaatg
     1621 ataaagaaag gaaagagctg ttttatggac aaaaaagaat tatttgacgc gctggatgat
     1681 ttttcccaac aattattggt aaccttggcc gatgtggaag ccatcaagaa aaatctcaag
     1741 agcctggtag aggaaaatac agctcttcgc ttggaaaata gtaagttgcg agaacgcttg
     1801 ggtgaggtgg aagcagacgc tcccgtcaag gccaagcatg ttcgcgaaag tgtccgtcgt
     1861 atttaccgtg atggatttca cgtatgtaat gatttttatg gacaacgtcg agagcaggac
     1921 gaagaatgta tgttctgtga tgagttgtta tacagggagt aggcatgcaa attcaaaaaa
     1981 gttttaaggg gcagtctccc tatggcaagc tgtatctagt ggcaacgccg attggcaatc
     2041 tagatgatat gacttttcgc gctatccaga ccttgaaaga agtggactgg attgctgctg
     2101 aggatacgcg caatacaggt cttttgctca agcattttga catttccacc aagcagatca
     2161 gttttcatga gcacaatgcc aaggaaaaaa ttcctgattt gattggtttc ttgaaagcag
     2221 ggcaaagtat tgctcaggtc tctgatgccg gtttgcctag catttcagac cctggtcatg
     2281 atttggttaa ggcagctatt gaggaagaaa ttgcagttgt gactgttcca ggtgcctctg
     2341 caggaatttc tgccttgatt gccagtggtt tagcgccgca gccacatatc ttttacggct
     2401 ttttaccgag aaaatcaggt cagcaaaagc aatttttcga ctcgaaaaaa gactatcctg
     2461 aaactcagat tttttatgaa tcgtcccatc gtgtggcaga tacattggaa aatatgctag
     2521 aagtctacgg tgaccgctcg gtagtcttgg tcagggaatt gactaaaatc tatgaagaat
     2581 accaaagagg taccatttct gaattgctgg aaagcatcgc tgaaacgcca ctcaagggcg
     2641 aatgccttct tattgttgaa ggtgccagtc aggatgtgga ggaaaaagac gaggaggact
     2701 tgttcttaga aatccaagcc cgtatccagc aaggcatgaa gaaaaatcaa gctattaagg
     2761 aagtagctaa gatttaccag tggaataaga gtcaactcta cgctgcctac cacgattggg
     2821 aagaaaaaca ataaagggag acagaatgta ataattctgt ctgtttctgt ttaacttaat
     2881 tagtgatggt aatataaaga tgtatcactt ggtatagaag ctttggtatt aagtttttta
     2941 ttaagcccat acggaatacc gatggttgga gcagcagtta tagcgttctt agaaggtata
     3001 aatagaaaaa taaggtcatt ttaaatcaaa ggattgataa atcagaaaga aggtgatttt
     3061 ttgcgaacat acgaaaataa agaagaacta aaagctgaga tagagaaaac atttgagaaa
     3121 tatattttag aatttgataa tattccagaa aatttaaaag ataagagagc tgatgaagtt
     3181 gacagaactc cagcagaaaa ccttgcttat caggttggtt ggaccaactt ggttcttaaa
     3241 tgggaagaag atgaaagaaa ggggcttcaa gtaaaaacac catcggataa atttaaatgg
     3301 aatcaacttg gtgaattata tcagtggttc acagatacct acgctcattt atctctgcaa
     3361 gagttgaaag caaaattaaa tgaaaatatt aattctatct ctgcaatgat tgattcgttg
     3421 agtgaggaag aattatttga accgcatatg agaaagtggg ctgatgaagc gactaaaaca
     3481 gcgacttggg aagtgtataa gtttattcat gtaaatacgg ttgcaccttt tggaactttc
     3541 agaactaaaa tcagaaaatg gaagaagata gtattataaa ttatattttt aactttaaaa
     3601 aatttcataa aaatggttac caaaggcgat agaagaaaaa ctatcgtctt tttctttgca
     3661 aatttttaag aagggaggtg atcttgcatg gactttgaat atttttataa cagagaagcg
     3721 gaaagattta acttcttaaa agtaccggag atattagttg atagagaaga atttcggggc
     3781 ttatcagcag aagcaattat cctttattcc atacttctta aacagacagg aatgtcattt
     3841 aagaataact ggatagacaa ggaaggcaga gtatttatct attttactgt cgaagaaatt
     3901 atgaaaagaa gaaatatctc aaagccaact gccataaaaa cattagatga gcttgatgta
     3961 aaaaaaggaa taggactgat cgaaagagta aggcttggac ttggtaagcc gaacatcatt
     4021 tatgttaaag actttatgag tatatttcag gtaaaagaaa atgacttaca gaagtcaaaa
     4081 aacttaactt cagaagtaaa agattttaac ctcagaagta aagaaaatga acttcaagag
     4141 gttaagaacc ttgactctaa ctatatagag aataataaga gtaagtatag taagagagaa
     4201 tatagttttg gtgaaaacgg acttggaaca tttcaaaatg tgtttttagc tgctgaagat
     4261 atatcggatt tacaaatcat aatgaactca cagcttgaga attacattag acttcctgca
     4321 aaactagaat cctagttcat gattgataat accagcaatc aaattcattc gtaatccgaa
     4381 gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta ctttggcaaa
     4441 gatgttctca accttgcttc tctccttaga tagcgcatgg ttacaggctt tatcttcagc
     4501 tgttagcggc ttgagtttgc tggatttacg tggagtttgt gcttgaggat atatcttcat
     4561 gagcccttga taaccactgt cggccaagat tttaccagct tgtccgatat ttctacaact
     4621 cattttgaac aacttcatat catgactata gttcacagcg atatccaaag aaacaattct
     4681 cccttgactt gtgacaatcg cttgagcctt catagcgtga aatttctttt taccagaatg
     4741 attcgctaat tgttttctta gggcgattga tttgtacttc cgtcgcatca atcattaccg
     4801 tgtcctcaga actgagagga gttcttgaaa tcgtaacacc acctttgaac aagagttact
     4861 tcaacccatt ggctccgacg gagtaagttg ctttcgtgga taccaaaatc agccgcaatt
     4921 tattcataag tgcgatattc tcgcacatat tgaagagtgg ccataagaag gtcttctagg
     4981 cttaatttag gttttcgtcc accttttgcg tatttaagtt gataagctgt ttttaataca
     5041 gctaatatct cttcaaaagt cgtgcgctga acaccaacaa gacgcttaaa tcgtgcatca
     5101 gttagttgtt tacttgcttc ataattcata gaactactat accatatttt gtttcgcagg
     5161 aagtctattg gaaagtaaga aatattggag ctgaggcgat tagaagaaat tgtgagcgtg
     5221 gtgctatttt ttcaggtaaa ataaaacatc acgaagattc tcagtttaaa ggagagcact
     5281 atgttgaatg ttatgctgtt ttagataata cggttatagc aagagataga ataacagtcc
     5341 ctatcgatcc gttatgtgga aaagatttta tagagtagca tataattgat tcttaactgg
     5401 aatactctct atctctttac atcaagaaaa tgactaaaca gggaagtttg ccttcttccc
     5461 tttttttgtt atactagtag aagaaaaaaa tagaaagatt tgtgggagtg a
//
LOCUS       DAVBOM010000084         5466 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBOM010000084 DAVBOM010000000
VERSION     DAVBOM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.085"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            1..1141
                     /locus_tag="VQ878_002025"
                     /pseudo
     CDS             1..1141
                     /locus_tag="VQ878_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            1165..1321
                     /locus_tag="VQ878_002026"
                     /pseudo
     CDS             1165..1321
                     /locus_tag="VQ878_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1314..1487)
                     /locus_tag="VQ878_002027"
     CDS             complement(1314..1487)
                     /locus_tag="VQ878_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET3096308.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(1646..3253)
                     /locus_tag="VQ878_002028"
     CDS             complement(1646..3253)
                     /locus_tag="VQ878_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET3096309.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            3406..4890
                     /locus_tag="VQ878_002029"
     CDS             3406..4890
                     /locus_tag="VQ878_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET3096310.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4985..>5466
                     /locus_tag="VQ878_002030"
     CDS             4985..>5466
                     /locus_tag="VQ878_002030"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET3096311.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1616 a         1237 c         1002 g         1611 t
ORIGIN      
        1 aaaaaccttc taaaattcct tatcttgaaa caactggtat gcctactaga attctcctta
       61 gaaagcgtcg ctttaagtgc tatcactgtt caaaaatgat ggtcgctgaa acttctatcg
      121 tcaagaaaaa tcaccaaatt cctcgtatta tcaaccaaaa aattgcgcaa aagttaattg
      181 aaaagaattc tatgaccgat attgcccatc agctggccat ctcaacttca actgttattc
      241 gtaagctcaa tgattttcac tttaaacatg atttttcttg tcttcctgag attatgtctt
      301 gggatgagta tgcttttaca aagggaaaga tgagcttcat tgcgcaagat tttaacaagc
      361 tcaatatcat cactgttctt gagggaagaa cacaagctat cattcgaaat cactttcttc
      421 gctacgatag agctgtccga tgtcgcgtca aaattattac tatggatatg tttagccctt
      481 actatgactt agctaaacag cttcgctttc aaatttctag gctcaggctg aaacagtctc
      541 ctagactgtt tcactcccga atgctaaaat cgttcttgat cgctttcata ttgtacaaca
      601 tcttagccgt gctatgagtc gtgtgcgtgt tcaaatcatg aatcagtttc atcgaaaatc
      661 ccatgaatac aaggctatca agcgctactg gaagctcata caacaggata gtcgtaaact
      721 cagcgataaa catttttatc gccctacttt tcgtatgcat ttaaccaata aagagatttt
      781 aaacaagctt ttgagctatt cacaagactt gaaacatcac tatcagctct atcaactctt
      841 gctgtttcac tttcagaata aggaaccgga gaaatttttc ggactcattg aggacaatct
      901 taagcaggtt catcctattt ttcagactgt ctttaaaacc tttctaaagg acaaagagaa
      961 aatagtcaac gcccttcaac taccctattc aaacgccaaa ttggaagcga ccaataatct
     1021 catcaaactt atcaagcgca atgcctttgg ttttcggaac tttgaaaact tcaaaaaacg
     1081 gattttcatc gctctgaaca tcaaaaaaga aaggacgaaa tttgtccttt ctcaagctta
     1141 gcttttcttc aacccactac agttgacaaa gagcctaagc ttttacctct tcctccctac
     1201 tcacctgagt acaatcctat tgagaaaaca tgggctcata tcaaaaagca cctcataaaa
     1261 ggtattacca agttgcaata ccttttatga ggctcttttg tcttgttctt gtttcaattg
     1321 actatattat cagtgtaata gtctaataga tagttaaatg tagttggatt tccactaaag
     1381 gttgatgagt aagtttttgt atctgaacct gattggccgc aagcagctaa aagcaaaaca
     1441 gatgcaaaag tcaggcctgc actaaggaca cgcttcttta tgttcatctt ctttctcctt
     1501 aatagtggga atttgtaaag ttaattgaat ttcgagaatg aaagtttata aaccttggtt
     1561 ataaaaaaca aaggatttct gctttttata cagtcctccc ttgtttttat atgatttcaa
     1621 ttttaaattt ttctgcaaaa aatatttata gtaattccac acagaaagca tcccatggaa
     1681 ctaagatttg tttttcaaag acttcttgag ctagggtgtt ttcaatcaag acagatttga
     1741 cttttccttc tactgtcaag tcttgctctt cattggacaa gttagccaca actaggaagc
     1801 gacggtcgcc atccttacgt atataagcaa agaccttatc agccgtatca agcaattcaa
     1861 agtcagctcg aactagccag ctattctcct tgcgaatttg gaccagtttc tgataggtat
     1921 agaaaataga atctggattt gccagcgctt cttggacatt gatcatctcg taatttggat
     1981 taaccgccaa ccaaggttga cctgttgaga aaccagcgtt tttgctctcg tcccattgca
     2041 taggggtacg ggcattgtca cgtccaataa cacggatact gtccatgatt tcttcaatcg
     2101 gaacaccttt ttcaagagcc tcacgcgcat agttgagaga ttcaatatct tctacttgat
     2161 ccagcgtttc aaagggatag ttggtcatgc caatttcctc accttggtag atataaggag
     2221 ttcctctcat gagatgaagc aagatggcaa aggctttggc agatttttcg cggtattctt
     2281 ggtcatttcc ccagattgag acaatacgag ggaggtcatg gttgttccag aagagggaat
     2341 tccagccgtc ctcaactcct aactctgtct gccatttgtt gaagatttct tttaacttag
     2401 cgatattcag ctctttttga tagtgccatt taggctgacc ttcctgatac tgaagaccga
     2461 tatgttcaaa ctggaagacc atagacaatt cttgcccctt tggatcagag tagagcttgg
     2521 caatctctgg cgttgctccc caagtctccc ctactgtcaa gagatcctta tctccaaagg
     2581 tcgcctgatt catttccttg agatagggat ggagcatagg accattattg actaccttct
     2641 cgtcaggaat tttgccaatc atgtcaataa catccatacg gaaaccacca atacccttat
     2701 caatccagaa gttcatcatc tcataaattt tctggcgaag tttttcattt tcccagttga
     2761 gatccggctg tttcttgctg aaaaagtgga gatagtattg acctgacttt tcatcgtatt
     2821 cccaagcaga cccactaaag atagaatcta ggtcattggg ttcatcgcgc cagatatagt
     2881 agtctcgctc agggctatta ggattttcac aggcctctac aaaccaggca tgctcatccg
     2941 aggtatgatt gaccaccaag tccatgatga tacggatatc acgcttctta gcttctgcaa
     3001 tcagttgatc catatcctcc atggttccaa aaatcgttgc aatcgcttga taatcagcaa
     3061 tatcgtagcc attatcatcc atagggctgt cataaacggg agaaagccaa attgctgtga
     3121 ttcctagctt ggctagatag tccaacttac tggtaattcc tggcaaatcg ccaattccat
     3181 ctccattact atccataaaa ctctttggat agacttgata gactacggca ttgtgccacc
     3241 atttttcttg catcttctta cctcattatt ttcataatct atagtctatg atagcacttt
     3301 ttaaaatttt gtgcaagcgt ttgcttaatc tttttaattt cttttttagc tccgtagttt
     3361 cctaacttcc aattttttat tataatagag tccagaggta aaaaaatgaa aaaacaagct
     3421 tttagttctg aacaatattt gaatttacaa cgcgaccata ttttggagcg cattaaccaa
     3481 tttgacggca agctctactt agagtttggc ggtaaaatgt tagaagattt ccacgctgct
     3541 cgtgtccttc ctggttatga acctgacaac aaaatcaagc tcttgcaaga attgaaagag
     3601 caggttgagg ttgtgattgc cattaatgct agcaacattg aacattccaa agcacgtggc
     3661 gacttaggca tttcttatga ccaagaagtt cttcgtttga ttgacaaatt caatgaatta
     3721 gggatttttg ttggttccgt tgtcattaca caatacgctg gccaacccgc tgcagatgcc
     3781 ttccgcaatc aacttgagaa aaacggaatt gattcttatc ttcattatcc aatcaaagga
     3841 tatccgacgg atatggatca catcatttcc ccagaaggca tgggcaaaaa cgactacatc
     3901 aaaaccagtc gcaacttgat tgtcgtaacc gctcctggac ccggttctgg aaaattggca
     3961 acgtgtatgt ccaatatgta ccacgaccaa atcaatggca tcaagtctgg ctacgctaaa
     4021 tttgaaacct tccctgtttg gaatcttccc cttcatcacc cagttaactt ggcttatgaa
     4081 gctgccacag ctgaccttga tgatgtcaac atgattgacc ccttccatct tcaaacctat
     4141 ggagaaacca ctgtcaacta caaccgtgat atcgaaatct tcccagtgct caagcgcatg
     4201 ttggaacgta ttctcggaaa atcaccatac gcttcaccga cagatatggg tgtcaacatg
     4261 gttggtttcg ctattacaga tgacgaggct gctgtcgaag cttctaaaca agaaatcatc
     4321 cgccgttact atcaaacagt tcttgacttc aaagctgaaa aagttggcga agctgccgtc
     4381 aagaaaattg agttactcat gaacgacctc ggtatcacac ctgcagaccg taaggttgct
     4441 gtcgttgcgc gccaaaaagc agaagaaact ggtggaccag ccctagcctt tgaattgcca
     4501 aatggggaaa tcatcactgg taagaactca gaactctttg gccctacagc cgctgccttg
     4561 atcaatgcca tcaaaaaatc agctgacatc gctaaagaag taaaactaat cgagcctgaa
     4621 gttgttaagc caatccaagg tcttaaaatc gatcatctcg gtagccgcaa tccacgcctt
     4681 cattcaaatg aaatcctgat tgcacttgct atcacagcta cagaaaatcc tgatgctgcc
     4741 cgcgctatgg aagaactcgg caacctcaaa ggaagcgaag cccactcaac catcatcttg
     4801 actgatgaag acaagaatgt ccttcgtaaa ctgggtatca acgtaacctt tgacccatac
     4861 taccaatacg accgcttata tcgtaagtaa agatttcaac ctctccagcc tcggagaggt
     4921 tttctctctg tctcaggagc aacctttatg atataatgag agaagaaaac tgaaaggatt
     4981 taccatgtca aaagaagtta ttgtcgaaag ttttgaactt gaccacacca ttgtcaaagc
     5041 accctatgtt cgcttgattg gggaagaaac aggaccaaaa ggagacatca tctccaatta
     5101 tgatattcgc ttggtgcaac caaacgaaga ctctatccct actgccggcc ttcacactat
     5161 cgagcacctc ttagccaaac tcatccgtac ccgcattgac ggcatgattg actgttcacc
     5221 atttggttgc cgcacaggct tccacatgat tatgtgggga cgtcacacca gtgctaaaat
     5281 cgcagctgtt atcaaggatt cgctcaagga aatcgctgaa actactactt gggaagatgt
     5341 cccagggaca accatcgaat cttgcggaaa ctacaaggac cacagcctct tctctgctaa
     5401 agaatgggca aaactcatct tggaacaagg gatttcagat gatgcctttg aacgtcatgt
     5461 gattta
//
LOCUS       DAVBOM010000085         5438 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBOM010000085 DAVBOM010000000
VERSION     DAVBOM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.086"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ878_002031"
     CDS             complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ878_002031"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET3096312.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEID"
     gene            complement(1663..3090)
                     /locus_tag="VQ878_002032"
     CDS             complement(1663..3090)
                     /locus_tag="VQ878_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3096313.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3255..4127
                     /gene="hslO"
                     /locus_tag="VQ878_002033"
     CDS             3255..4127
                     /gene="hslO"
                     /locus_tag="VQ878_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET3096314.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            4114..5094
                     /gene="dusB"
                     /locus_tag="VQ878_002034"
     CDS             4114..5094
                     /gene="dusB"
                     /locus_tag="VQ878_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET3096315.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(5324..>5438)
                     /locus_tag="VQ878_002035"
     CDS             complement(5324..>5438)
                     /locus_tag="VQ878_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096316.1"
                     /translation="QWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT         1572 a         1287 c         1066 g         1513 t
ORIGIN      
        1 catcgatttc cgcaaagact tgagttgctt tcacagcctt cttccagccc ttgtagagtt
       61 gttccttgcg agattcgttc atagatggct caaagagttc tcctgtctcg ttcaagagtt
      121 tcaactcgtc caagtctttc cagtacccta ctgacaaacc tgctaggaag gccgctccta
      181 gagctgttgt ttccaagttt ttagcacgtg caatgtcaat gcctaaaata tccgcctgga
      241 actgcatgag gaagttgttc atggctgcac caccatccac cttcagtact tgaatggcgg
      301 tctgagtatc catttgcatg gtgtcgatga tgtcacgcac ttgataagca atagattgca
      361 aagtcgcctt gataaagtct tctttgcttg ttccacgagt caaaccaaag acggaaccac
      421 gagcattttg gttccagtat ggagcgccta gacctgtaaa ggctggaacg acataaactt
      481 catcgttgtt gtgagaatca cgagcgtatt tttcagattc tggtgaattt tcaaccatgc
      541 gaagaccgtc acgaagccac tgaatagcac ttcctgcgat gaagatagaa ccttccaagg
      601 cataataaac cttaccgttg attccgtaac caatggttgt caagaggttg ttttcagaca
      661 actgcatctc ttccccagta ttcatgatga tgaaagagcc tgttccataa gtattcttaa
      721 ccatacctgg ctcaaaagcc aactgtccaa agagggctgc ttgttggtcc ccagccatac
      781 ctgagattgg cacctctcca ccgtagaaat ggaatggagc tgtcttgccg tagatttcgg
      841 agttagaacg aacttctgga agtatagcct tcggaatgtt aaggatttcc aaaatctcat
      901 catcccattt gagttcttta atgttataaa gcatggtacg agctgcattt gagtagtcag
      961 tcacgtgagc cgcaccgtca gtcaatttcc aaaccaacca agtatcgata gtaccaaaga
     1021 gcaattcccc tttttctgct cgctcttgag caccttctac atgatccaaa atccaacgaa
     1081 ccttggtagc agagaagtaa gcatcaataa tcaaaccagt cttttcatgg aatttttcca
     1141 cataaccttg gctttttagt tgctcagcca aaggtgctgt ctggcgtgac tgccaaacga
     1201 tagcattgta gataggaagt cctgttttct tatcccagac aaccgttgtt tcacgttggt
     1261 tggtaatccc gattgcctcg atttgatttg gcttgacacc actttcgatg aaagcacccg
     1321 caataactga ctgaacagag ttccaaattt cattggcatt gtgctcaacc caacctgctt
     1381 gagggaaaat ctgggtaaac tctttttgac tcgagctaac cttttcccct tttttgttga
     1441 aaatgatggc acgagaactt gtagttccct ggtcaatggc catgatgtat ttttcttgtg
     1501 acatgtactg tcctcctgat aaagatcttg aggtgtttcc tctttacact tactagtata
     1561 caaaataaag cgctttcttg tttatcaact ttttttaatt tttaaaaaaa tgtgaggaga
     1621 ttgtgtgaat ttcacaaaaa agacctggat taaccaagcc ttttaagtga ataataactg
     1681 acgaatccct gccaaatctt ccatatccaa gtcatttttt aaataataga ctggtgtctg
     1741 ttccttctta tgaatagggt tattggtaac cagcaaatca taatgccgac tagggtcata
     1801 agcttcaatg gtaataaaac gattgtattc caaataccgt ttcaaaatgg ctgccatcct
     1861 tgaaaagaca agaaaaccag atgtcaaatc cagaccaatc cgcatatgct ggccaccgtt
     1921 ttcagccata tattcgatta actggagcca ttcccagaga atcttcttat ctaaatctgt
     1981 cccctgttga aaagcaggta gagcatgaaa aatctcctct gctgtctctt taaaatcatg
     2041 ttccatcagt aaatatggat gacgattctc taactggtac ttgtagcgat cctgtaaaat
     2101 atagccctta tagagataga cttgagcaca aagctgactg agttcatagg tgacatggtc
     2161 ctctgtataa tcccccaata gttcctcctt cttcatttct tgaatcaatt gcgtcagtaa
     2221 atctgccaac tgccctccaa aaccaagaat atactccata gtatgaagag gaagaatgcg
     2281 atgagatagg agaaaagaga agaatatcat catctcacca tcctcaactc ctagtggaat
     2341 atgttgccca gcaaaaaagg acggaacctt tctcagcaaa cgaagataga agatattgtc
     2401 aaaataccct cgcattttct cttctataac ttgaaactga caagcattga cccgaagacg
     2461 ttgttgactg atgtgagccc agagaaccaa gtccaatttc tgccccgcag acaaacttgc
     2521 accgcagatt tcctctaaat tggcaatctc ctgttttctc tctggtttct gcatgtgacc
     2581 ttcccattcc tgactcgacc agacctttcg gaaaagacag aaatagaaat agcgaatctg
     2641 atgctctgga cctcgccaac gtccattttg gatggataaa tcaaattctg acaaaatctg
     2701 atttaaacca gccaagtgac gaccaagcgt agcctcgcta atcactaatt cttgagccag
     2761 ctgatgggct aaaaactgtt ggtggtagag aagataaacc aaaatctggt atttaacagc
     2821 actctccaaa aacaagctcc gaatatctct ccccttggta gctgcaccga tagacagacg
     2881 cagattttca tcttctgagt gaatagtcag ttctaagcca ctatccaaag ccttgtcatt
     2941 gagcagggtg acatatttgg ttagggttgc ttttgaaaat cctgtttctt ccattacagc
     3001 cttgacggtc gtctgagact cttgtaatag aaaggaaagg attgaaaatt gaccacactc
     3061 ggctttctcc atcaaatctc ctaaatacat ttgttatccc tttcattttc taccttaagc
     3121 atagcataaa tcttacaaat gctaaaataa tctgtttctc tttttatttt catgctgatt
     3181 tcctggtcca ttatcctgaa aatcagtaaa cacacggctc cccctttggg catttttatg
     3241 ctaaaatagt agctatggat aaaattatta aaactatatc agaaagcgga gcctttcgtg
     3301 cttttgtcct tgatagcact gaaaccgtcc gcactgctca agaaaaacat caaacccaag
     3361 ctagctcaac tgtagcgctt ggtcgaactc ttatcgccag ccagattctc gcagccaatg
     3421 aaaaaggaaa taccaaactt acagttaagg tgttgggatc tagctctcta ggtgctatta
     3481 tcaccgtcgc tgataccaag gggaacgtca aaggctatgt tcaaaatcct ggtgttgaca
     3541 tcaaaaagac tgcgactggt gaagtcctag tcggaccttt tgttggaaat ggtcaattcc
     3601 tcgttatcac agactacggt actggaaatc cttacaactc tataactccc ctcatctctg
     3661 gagaaatcgg tgaagacctt gccttttacc ttactgaaag ccaacaaacg ccttcagcgg
     3721 tcggcctcaa tgtccttttg gacgaggaag acaaggtcaa ggttgcaggt ggtttcctag
     3781 ttcaagtctt gccaggagcc aagaaagaag agattgctcg ctttgaaaaa cgcatccaag
     3841 aaatgccagc tatctctact cttctcgaaa gcgacgacca tatcgaagcc ctcctcaagg
     3901 ctatctacgg ggacgaagcc tacaagcgtc tttctgaaga agaaatccgt ttccaatgtg
     3961 actgtagcca tgaacgcttt atgaacgctc ttgccagcct tccaagctca gacttacagg
     4021 aaatgaaaga ggaagaccac ggtgcagaaa tcacttgtca attctgccaa actacttaca
     4081 actttgatga aaaggacctg gaggaactca ttcgtgacaa atcttaatac accttttatg
     4141 attggcaata ttgagattcc caatcgtacc gttttagcgc ctatggctgg cgtgaccaac
     4201 tcagcctttc gtaccatagc aaaagagctc ggagctggac tcgttgtaat ggaaatggtc
     4261 tctgacaagg gaatccaata caacaacgaa aaaaccctgc acatgcttca tatcgatgag
     4321 ggcgaaaacc ctgtctctat ccaacttttt ggtagcgatg aagacagcct agcacgcgca
     4381 gcagaattca tccaagaaaa caccaagacc gatatcgtcg atatcaacat gggctgccct
     4441 gtcaacaaaa tcgtgaagaa cgaagctggt gctatgtggc tcaaggatcc tgacaagatc
     4501 tactctatca tcaacaaggt ccagtctgtc cttgatatcc cacttactgt caaaatgcgt
     4561 accggctggg cggacccatc tcttgcagta gaaaatgccc tcgctgctga ggctgcaggt
     4621 gtttctgccc tcgccatgca tggccgtacc cgtgaacaaa tgtatactgg ccacgcggac
     4681 cttgagaccc tttacaaggt tgcccaagct ctaaccaaga ttccattcat cgccaacggt
     4741 gatatccgta ctgtccaaga agccaagcaa cgcatcgaag aagttggtgc tgacgcagtc
     4801 atgattggcc gagctgccat gggaaatcct tacctcttca accaaatcaa ccattacttt
     4861 gaaacaggag aaatcctacc tgatttgaca tttgaagaca agatgaagat cgcctacgaa
     4921 cacttgaaac gattgattaa cctcaaagga gaaaacgtcg cagttcgtga attccgcggc
     4981 ctcgctcctc actatctccg tggaacatct ggcgctgcca aactccgtgg agccatttcg
     5041 caagctagca ccctagcaga gattgaagcc ctcttgcaat tggagaaggc ttaatagttt
     5101 aaaacccgta actctcttaa agagcctctt gaatgccgcc attctttcct catcaaaaaa
     5161 actccgtagt ctctagcgct ataaatccgg ctagagatta cagagttatt ttttaatcta
     5221 aacttcctac aagggtatat tatctactga aaggatatgg tatttgtagg gaatacttta
     5281 aagagttctt acaggaagtc agtattaact agttatatta ggtttagttt acccattcac
     5341 cattggcatt gactccatag ccatctacag ttgtgttgac tgcaagggca cctgagccat
     5401 tgacatagta ccatttatct gatactttga accattgg
//
LOCUS       DAVBOM010000086         4996 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBOM010000086 DAVBOM010000000
VERSION     DAVBOM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.087"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            298..1843
                     /locus_tag="VQ878_002036"
     rRNA            298..1843
                     /locus_tag="VQ878_002036"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1895..1967
                     /locus_tag="VQ878_002037"
     tRNA            1895..1967
                     /locus_tag="VQ878_002037"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1928..1930,aa:Ala,seq:tgc)
     gene            2092..4993
                     /locus_tag="VQ878_002038"
     rRNA            2092..4993
                     /locus_tag="VQ878_002038"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1408 a         1017 c         1468 g         1103 t
ORIGIN      
        1 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcggtt
       61 ggaacacttg atgaaaaaaa gtttaaaaaa gcttaaaaat cttcaaaaaa gtgttgacaa
      121 gcgaaagcgg ctgtgatata ctaatatagt tgtcgcttga gagaagcgag tgacaaagac
      181 ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct acaacataag ttgtagtact
      241 gaacaatgaa aaaaacaata aatctgtcag tgacagaaat gagtgagaac tcaaactttt
      301 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta
      361 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag
      421 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt
      481 agatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt
      541 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag
      601 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta
      661 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt
      721 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact
      781 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt
      841 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt
      901 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc
      961 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac
     1021 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc
     1081 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc
     1141 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg
     1201 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta
     1261 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgacga ctctagagat
     1321 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt
     1381 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcatttag
     1441 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat
     1501 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc
     1561 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa
     1621 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg
     1681 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg
     1741 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta
     1801 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tttctaagga taaggaactg
     1861 cgcattggtc ttgtttagtc ttgagaggtc ttgtggggcc ttagctcagc tgggagagcg
     1921 cctgctttgc acgcaggagg tcagcggttc gatcccgcta ggctccattg gtgagagatc
     1981 accaagtaat gcacattgaa aattgaatat ctatatcaaa tagtaacaag aaaataaacc
     2041 gaaaacgctg tagtattaat aagagtttat gactgaaagg tcagaaaata aggttaagtt
     2101 aataagggcg cacggtggat gccttggcac taggagccga cgaaggacgt gacaaacgac
     2161 gatatgcctt gggtagctgt aagtaagcga tgatccatgg atttccgaat gggggaaccc
     2221 aacaggtaat acctgttacc cacatctgtt aaggatgtga ggaggaagac gcagtgaact
     2281 gaaacatcta agtagctgca ggaagagaaa gcaaaagcga ttgccttagt agcggcgagc
     2341 gaaacggcag aagggcaaac cgaagagttt actcttcggg gttgtaggac tgcaatgtgg
     2401 actcaaagat tatagaagaa tgatttggga agatcagcca aagagagtaa tagcctcgta
     2461 tttaaaatag tctttgtacc tagcagtatc ctgagtacgg cgggacacgt gaaatcccgt
     2521 cggaatctgg gaggaccatc tcccaaccct aaatactccc tagtgaccga tagtgaacca
     2581 gtaccgtgag ggaaaggtga aaagcacccc gggaggggag tgaaatagaa cctgaaaccg
     2641 tgtgcctaca acaagttcga gcccgttaat gggtgagagc gtgccttttg tagaatgaac
     2701 cggcgagtta cgttatgatg cgaggttaag ttgaagagac ggagccgtag ggaaaccgag
     2761 tctgaatagg gcgccttagt atcatgacgt agacccgaaa ccatgtgacc tacccatgag
     2821 caggttgaag gtgcggtaag acgcactgga ggaccgaacc agggcacgtt gaaaagtgct
     2881 tggatgactt gtgggtagcg gagaaattcc aaacgaactt ggagatagct ggttctctcc
     2941 gaaatagctt tagggctagc gtcgacatta gagattcttg gaggtagagc actgtttggg
     3001 tgaggggtcc atcccggatt accaatctca gataaactcc gaatgccaat gaattatggt
     3061 cggcagtcag actgcgagtg ctaagatccg tagtcgaaag ggaaacagcc cagaccacca
     3121 gctaaggtcc caaaataatt gttaagtgga aaaggatgtg gggttgcaca gacaactagg
     3181 atgttagctt agaagcagct attcattcaa agagtgcgta atagctcact agtcgagtga
     3241 ccctgcgccg aaaatgtacc ggggctaaaa caatttaccg aagctgtgga tacctttata
     3301 ggtatggtag gagagcgttc tatgtgtgat gaaggtatac cgtgaggagt gctggaacgc
     3361 atagaagtga gaatgccggt atgagtagcg aaagacaggt gagaatcctg tccaccgtaa
     3421 gactaaggtt tccaggggaa ggctcgtccg ccctgggtta gtcgggacct aaggagagac
     3481 cgaaaggtgt atccgatgga caacaggttg atattcctgt actagagtat gtagtgatgg
     3541 agggacgcag taggctaact aaagcagacg attggaagag tctgtctaag cagtgaggtg
     3601 tgaattgagt caaatgctta attctataac attgagctgt gatggggagc gaagtttagt
     3661 agcgaagtta gtgacgtcac actgccaaga aaagcttcta gcgtttaaac atactctacc
     3721 cgtaccgcaa accgacacag gtagtcgagg cgagtagcct caggtgagcg agagaactct
     3781 cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag aaggggtgct gactttaagt
     3841 cagccgcagt gaataggccc aagcaactgt ttatcaaaaa cacagctctc tgctaaatcg
     3901 taagatgatg tatagggggt gacgcctgcc cggtgctgga aggttaagag gagtgcttag
     3961 cgtaagcgaa ggtatgaatt gaagccccag taaacggcgg ccgtaactat aacggtccta
     4021 aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta atgatttggg
     4081 cactgtctca acgagagact cggtgaaatt ttagtacctg tgaagatgca ggttacccgc
     4141 gacaggacgg aaagacccca tggagcttta ctgcagtttg atattgagtg tctgtaccac
     4201 atgtacagga taggtaggag tctaagagat cgggacgcca gtttcgaagg agacgctgtt
     4261 gggatactac ccttgtgtta tggccactct aacccagata ggtgatccct atcggagaca
     4321 gtgtctgacg ggcagtttga ctggggcggt cgcctcctaa aaggtaacgg aggcgcccaa
     4381 aggttccctc agaatggttg gaaatcattc gcagagtgta aaggtataag ggagcttgac
     4441 tgcgagagct acaactcgag cagggacgaa agtcgggctt agtgatccgg tggttccgta
     4501 tggaagggcc atcgctcaac ggataaaagc taccctgggg ataacaggct tatctccccc
     4561 aagagttcac atcgacgggg aggtttggca cctcgatgtc ggctcgtcgc atcctggggc
     4621 tgtagtcggt cccaagggtt gggctgttcg cccattaaag cggcacgcga gctgggttca
     4681 gaacgtcgtg agacagttcg gtccctatcc gtcgcgggcg taggaaattt gagaggatct
     4741 gctcctagta cgagaggacc agagtggact taccgctggt gtaccagttg tcttgccaaa
     4801 ggcatcgctg ggtagctatg tagggaaggg ataaacgctg aaagcatcta agtgtgaaac
     4861 ccacctcaag atgagatttc ccatgattat atatcagtaa gagccctgag agatgatcag
     4921 gtagataggt tagaagtgga agtgtggcga cacatgtagc ggactaatac taatagctcg
     4981 aggacttatc caaagt
//
LOCUS       DAVBOM010000087         4657 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBOM010000087 DAVBOM010000000
VERSION     DAVBOM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.088"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(92..529)
                     /locus_tag="VQ878_002039"
     CDS             complement(92..529)
                     /locus_tag="VQ878_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET3096317.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(614..3247)
                     /gene="polA"
                     /locus_tag="VQ878_002040"
     CDS             complement(614..3247)
                     /gene="polA"
                     /locus_tag="VQ878_002040"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET3096318.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3503..3853
                     /locus_tag="VQ878_002041"
     CDS             3503..3853
                     /locus_tag="VQ878_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3096319.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4068..4172
                     /locus_tag="VQ878_002042"
     CDS             4068..4172
                     /locus_tag="VQ878_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3096320.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGG"
     gene            4177..4410
                     /locus_tag="VQ878_002043"
     CDS             4177..4410
                     /locus_tag="VQ878_002043"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096321.1"
                     /translation="MFSQLRMREEQALLAQDYALETARAGGIEQGLERGKVEGREERK
                     LFAFLDIVRQDLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1424 a         1109 c          860 g         1264 t
ORIGIN      
        1 gtgttttgag cagcccgcgg ctagtttcct agtttgctct ttgattttca ttgagtataa
       61 cacaaaaggt agcccatcag ctaccttttt cttatgcttc ctcaatcaag cgagtatgtt
      121 ctctcttgat acagcgattc atcacgatat catcacatcc accatcacgc aaaatctctt
      181 tcgcttttaa actttcaagt cctagctgtg cccaaaaaat cttggcatca gctttgagaa
      241 aatcacgcgc cacatcgggc agaaattcac tgcgacgata aacattgaca atatctacag
      301 gaaaaggaat ttcagcgagg ctagcataag ccttttcacc caagatttcg ccacctgccg
      361 ccttgggatt gactgggatg attttatagc cccgagcctg catttccttt gtcactcgat
      421 tgctggttgt ttcttcacgg tcagacaaac ccaccacagc aagggtttta ctcgttgcga
      481 gatactgacg aatcacgcca tcacttggat tgataaattc ttgactcata gaaaacctcc
      541 tttttcatca gtatagcaca ttttgaaaag gtttgcagaa ttctactaca aaaaaggagg
      601 actagccccc tttttattta gcctcgtacc aggttgcccc ttcattctca tctgcgataa
      661 gaggaacact gagttgaatg gcttcttcca tggtttgttt caccaatttt ttcatctcta
      721 ccaattcaga tttaggcact tcaaggacga tttcatcgtg cacttgtaac agcatcttag
      781 tctgataacc acctgcaacc aaggctttat ccagctgaat catggcaatc ttgagaatat
      841 ctgctgccga accctggata ggtgagttga tagcagttcg ctccgcaaaa ccacgaatat
      901 tgaagttgcg cgaattgata tctggcaact cacggcgacg cttaaagagg gtctctacat
      961 agcccttatc acgcgcctcc cgcaccactt catccatgta gtttttaata cctggaaaac
     1021 gttcaaagta ggtatcaatg taggctttgg cttccttacg actaattccc aaattattag
     1081 acaagccaaa gtctgaaatc ccataaacca ctccaaagtt aactgccttg gcattgcgac
     1141 gatcatttgc agtcacatta tcaggacgct caatgccaaa gacccgcatg gctgtcgaag
     1201 tatggatatc tgccccctct tggaaggcct taatcaagtg ctcatcctta gaaatatgcg
     1261 ccaaaacgcg caattcaatc tgtgaatagt cagagctgag tagcacacta tcctcccact
     1321 ctggcacaaa agccttccga atcaagcgcc cttgttccaa tcgggcagga atattttgca
     1381 agtttggatc cacactagac aaacgcccgg tctgggtcaa atcctgcata tagcgagtat
     1441 gaatctttcc atcagccaaa atccagtcct gcaagccaat tacataagta gattgaatct
     1501 tagcaatttg acggtaatcc aggattttct taacaatcgg agcaatagga gcgagacgct
     1561 ccaacacatc cactgctgtc gaataacctg tcttggtttt cttagtgtat tctagaggaa
     1621 gtcccaattt ctcaaagaga agcacgccca actgcttagg cgagttgaca ttaaactcct
     1681 caccagccag ctcgtaaatc tcttgagtca gtttttcaat gacaagctca ttttcagcct
     1741 gcatctcaag caaggtctct ttcttgacca taatcccagc aatttccatc ttggcaagga
     1801 caaaagccag aggttgctcc atatcataaa gaagctctaa ttgcccattt tcgctgagtt
     1861 tttcaagtaa aataggctct gtttctacca aaacagcaag tttacaagct aagtgttcca
     1921 agaatttctc acgttcagga atggcctttt taacaccctt accgtagaaa gtttcatcat
     1981 caaccaagta agtctgacca taaagactag cgatggtcgc aatttcattg tcctccacag
     2041 tcgaaaggag gtatttagcc aaacggatgt caaaagcagg cgcctgcaaa tccacaccaa
     2101 aacgttgcaa aagaacttta accttcttaa agtcataaac tctcagagat gttttttcta
     2161 agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt gtctgtggca tagagcttat
     2221 ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg gtaattctca ccaaaaagct
     2281 caaagtggaa gatggactct tcactcagca tatcttgact gatttggtca acaatagtaa
     2341 aatccaaact ctcagacaca tcagctgacg acacatttaa agcctgcttt agctgtttga
     2401 agcccatctc atcgtagaat ttcccaagat tttcaacatc tggaccacta tagaccaagt
     2461 cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt cgctagtgtt ttagataaaa
     2521 aggcctgttc cttgtcattg atgagatttt ccttcatctt agaagtcttc attccatcaa
     2581 tattttcata aatcccctca agcgaaccat gctccagcaa gagcttaata cccgtctttt
     2641 caccgacttt ggtcacccca gggatattat ccgacttatc acccatgagc gccttgagat
     2701 cgataaactg agctggtgtg aggcccattt cttccatgag gtaatctggc gtaaaggcct
     2761 caaactcagc cacacctttc ttggaaattt caaccaccgt atgctcatcc gtcagctgaa
     2821 tcaaatcctt gtccccactg acaatggtaa tatcaaaacc atcctgctct gctagcttat
     2881 ccagcgtccc aatgatgtca tccgcctcat actgagccag ctcatagtga cgaatcccca
     2941 tatgatccag caactcacga atgaaaggaa attgctcacg aaactcatca ggagtcttgg
     3001 cccgaccacc cttatagtcc gcatacatct ctgtccggaa ggtcgtcttt cccgcatcaa
     3061 aagccaccaa aatatgactc ggctcaaccc gctccaacaa atgactcaac atcaactgaa
     3121 aaccataaat cgcattggta tgcaaaccag ccgcattctt aaaacggtcc aactgctgat
     3181 acagcgcaaa aaacgcccga aaagctacag aagacccatc aatcaataat aattttttct
     3241 tatccataca cccattataa aggaaagaat caaaaaatac cattgggaag agctagagca
     3301 agtatttttc aaactttttc cgaataaata gatagagcca gagaatttag taaacctaga
     3361 tttaaaaatg tgctataata tagtatattg aatctataat agtacacctt gactgctaaa
     3421 atatttctat aaattaattt gactttcctg atagagttat tcacatctta tttcaactca
     3481 ctatagaagg aggaatagga ggattctcag acatccgggc atcagcccaa ctaatgattt
     3541 gattgctaag aaaatattca gcaatccaga aatcacttgt caatttattc gcgatatgct
     3601 ggacttgcca gcaaaaaatg tgaccatttt ggagggaagc gatattcacg tattactctc
     3661 catgccttac tcggtgcagg atttttatac cagtatagac gtcttggcgg agttggataa
     3721 cggtactcaa gtaattattg agattcaagt ccatcatcag aattttttca tcaatcactt
     3781 gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa aaaattcgtc agcgagaagg
     3841 tgatactcac tagatctaca aacacatcgc tcctgtttac gtcattgcta tcgtggatag
     3901 taattatttc tcagatgacc tggcttttca tagctttagt atgcgcgaag acacaacagg
     3961 tgaggtattg gcgattacca acaatggaca ggaaaaccat ctggttaaga tggcattctt
     4021 ggaattaaaa aatacagaga aaccagcaaa gacaaggttc gcaagccatg gttggagttt
     4081 ttcggcaaca agccctttac ccagcaaccg caacgagcca ttacccaagc aaatcaactg
     4141 ctggactaca agagctggtc cgaggaggat aggaaaatgt ttagtcaact acgtatgcga
     4201 gaagaacaag ccttgttagc gcaggactat gccttggaaa ctgctagggc gggaggtatt
     4261 gaacaaggct tagagcgtgg gaaagttgaa ggaagggaag aaaggaaact ttttgccttc
     4321 ctagacatag tacgccaaga tcttctgact tctgaggttg ccagccagca attaggtatg
     4381 tcagtatctg aatttgaggc actgttgtaa aatggctcca taatatccat agtgggtaaa
     4441 tcccctatgg atattatgga gcctattttg tgtagaaaaa aagtcccata tgacctataa
     4501 tgaaaagcga caaaacaact cattagaaag aatcatatgg aacaattaca ttttatcaca
     4561 aaattactag acattaaaga ccctaatgtc cagattttaa acatcatcaa taaggataca
     4621 cacaaggaaa tcatcgccaa actggactac gacgccc
//
LOCUS       DAVBOM010000088         4519 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBOM010000088 DAVBOM010000000
VERSION     DAVBOM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.089"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..271
                     /locus_tag="VQ878_002044"
     CDS             <1..271
                     /locus_tag="VQ878_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3096322.1"
                     /translation="WYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYL
                     EASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            672..1793
                     /gene="mnmA"
                     /locus_tag="VQ878_002045"
     CDS             672..1793
                     /gene="mnmA"
                     /locus_tag="VQ878_002045"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET3096323.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1934..2389
                     /locus_tag="VQ878_002046"
     CDS             1934..2389
                     /locus_tag="VQ878_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3096324.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2399..4312
                     /gene="mnmG"
                     /locus_tag="VQ878_002047"
     CDS             2399..4312
                     /gene="mnmG"
                     /locus_tag="VQ878_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET3096325.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1305 a          916 c         1103 g         1195 t
ORIGIN      
        1 atggtactac ctaaacgcta acggtgctat ggcaacaggt tgggctaaag tcaacggttc
       61 atggtactac ctcaacgcta acggttcaat ggcaacaggt tgggtgaaag atggagatac
      121 ctggtactat cttgaagcat caggtgctat gaaagcaagc caatggttca aagtatcaga
      181 taaatggtac tatgtcaatg gcttaggtgc ccttgcagtc aacacaactg tagatggcta
      241 tgaagtcaat gccaatggtg aatgggttta agccgattaa attaaatcat gttaagaaca
      301 tttgacattt taattttgaa acaaagataa ggttcgattg aataaattta tgttcgtatt
      361 ctttaggtac ctatcttatg atttcaggaa atgtcattaa aaaaacgact ccttttctct
      421 aacttgaaaa atagattaga gaaaatgggt tgttttattt attatagtta tttgaatgaa
      481 gataagaaga aggtatactc acatcattca cataatctgt atattgacta taagttttaa
      541 aaaacaattt ttaagctctt ccttgtcttc tctaaccaag cgtgttataa tgaatactgc
      601 tcaagcgacc ttcaatcgtg aagcacacac gaccttcaat cgtgaataaa cgaatagatg
      661 ggagacttac catgagtgat aactctaaaa cacgtgttgt cgtggggatg agtggtggtg
      721 ttgattcgtc ggtgacggct cttttgctca aggagcaggg ctacgatgtg atcggtatct
      781 tcatgaagaa ctgggatgac acagatgaaa acggcgtctg tacggcgacc gaagattaca
      841 aggatgtggt tgcggtggca gaccagattg gcattcccta ctactctgtc aattttgaaa
      901 aagagtactg ggaccgcgtt tttgagtatt tcctagcgga ataccgtgca gggcgcacgc
      961 caaatccgga cgttatgtgc aacaaggaaa tcaagttcaa ggcctttttg gactatgcca
     1021 tgaccttggg ggcagactat gtagcgactg ggcattatgc tcgagtggcg cgtgatgagg
     1081 acggcactgt tcacatgctt cgtggcgtgg acaatggcaa ggaccagacc tatttcctca
     1141 gccaactttc gcaagaacaa cttcaaaaaa ccatgttccc actaggacat ttggaaaagc
     1201 ctgaagttcg aaaactagca gaagaagcag gcctttcgac tgctaagaag aaagactcga
     1261 cagggatttg ctttatcgga gaaaagaact ttaaaaactt cctcagcaac tacctgccag
     1321 ctcagcctgg tcgcatgatg actgtggatg gtcgcgatat gggcgagcat gcaggtctga
     1381 tgtattatac aatcggtcag cgtggcggac tcggtatcgg tgggcaacac ggcggtgaca
     1441 atgccccttg gttcgttgtc ggaaaagatc taagcaagaa tattctctat gtaggacaag
     1501 gattctacca tgattcgctc atgtcaacta gcctagaagc cagtcaagtc cactttactc
     1561 gtgaaatgcc agaagagttt acgctagaat gtacggctaa attccgttac cgtcagcctg
     1621 actctaaggt gaccgtccat gtcaaaggag acaaggcaga ggtcatcttt gcggaaccac
     1681 aacgcgcgat tacaccaggc caggcagttg tcttttacga tggcgaagag tgtctaggtg
     1741 gtggtttgat tgacaatgct taccgcgatg gacaagtttg tcagtacatt tagattgaca
     1801 aattttctca atttgctaca ataataacag caatagaaat gatggtcaaa gctcatggat
     1861 gttgcaggct tttttgtcct gcacttcttt ggagttttga ctgtttttgt gtcgtttaag
     1921 ggaaaggaca agaatgactc aacaagactt tcggacaaaa gtagacaata cggtttttgg
     1981 tgttcgggcg acagctttga ttcttcaaaa tcacaagctt ctagtcacca aagacaaggg
     2041 caagtattac actatcggcg gtgcgattca agtcaatgaa agcacggaag acgcggtagt
     2101 ccgtgaagtg aaggaagaac tgggtgtcaa agctcaagct gggcagctag cttttgtggt
     2161 tgaaaatcgt tttgaacagg acggtgtttc ctatcacaat atcgagtttc attatctggt
     2221 ggacttactt gaggatgccc cattgaccat gcaggaagat gagaaaaggc agccctgtga
     2281 gtggattgac ttggataagc ttgaggatat ccagctagtt ccagcctttt taaaaacggc
     2341 cctaccagat tgggaaggcc aactaagaca cattcatctt gaggaatagg agagaaacat
     2401 gacttatcat tttactgaag aatacgatat tattgtaatt ggtgcgggac acgctggggt
     2461 tgaggcttcc ttggccgcta gccgtatggg ctgtaaggtc ctgcttgcga ccatcaatat
     2521 tgaaatgctg gctttcatgc cttgtaatcc ctctatcggt ggttctgcta aggggattgt
     2581 cgtacgtgaa gtcgatgccc tcggtggcga gatggccaag accattgaca agacttacat
     2641 ccagatgaag atgctcaaca cagggaaggg cccagccgtt cgtgcccttc gtgcgcaggc
     2701 tgataaggaa ctttactcta aggaaatgcg caagacagtt gaaaatcaag aaaatctgac
     2761 ccttcgtcaa accatgattg atgagatttt ggtggaagat ggcaaggttg tcggtgtgcg
     2821 tacagccacc catcaagaat atgctgctaa ggctgttatt gtgacgacag ggactgctct
     2881 ccgtggggaa attatcatcg gagacctcaa gtactcatca ggtcctaacc acagcttggc
     2941 ttctattaac ctagctgaca atctcaagga actgggtctc gaaatcggtc gtttcaagac
     3001 aggaacccct ccacgtgtca aggcttcttc tatcaattac gatgtgacgg aaattcagcc
     3061 aggagacgaa gtgcctaatc atttctcata cacttcacgt gatgaggatt atgtcaaaga
     3121 tcaagtgcca tgctggttga cctataccaa tggtaccagt catgagatta tccaaaacaa
     3181 cctccaccgt gcgcctatgt ttacaggtgt ggtcaaggga gtggggcctc gttactgtcc
     3241 gtcgattgaa gacaagattg tgcgctttgc ggacaaggaa cgtcaccaac tcttccttga
     3301 gccagaaggg cgcaatactg aggaagtcta tgttcaagga ctttcaacca gtctgcctga
     3361 ggatgtccag cgtgacttgg ttcattccat caaaggtttg gaaaatgcag agatgatgcg
     3421 gacaggttat gctattgagt atgatatggt cttgcctcat cagttgcgtg cgactttgga
     3481 aaccaagaaa atctcaggtc tcttcactgc tggtcagaca aatggaacat caggttatga
     3541 agaagctgct ggccaaggga ttatcgcggg tatcaatgcg gctctgaaaa tccaaggtaa
     3601 acctgagttg attctaaaac gaagtgacgg ttatatcggg gtgatgatcg acgacttggt
     3661 gaccaaggga accattgaac cttaccgtct cttgaccagt cgtgctgaat accgtctcat
     3721 tcttcgtcat gacaatgctg atatgcgctt gactgagatg ggacgcgaga ttggccttgt
     3781 ggatgatgaa cgctgggctc gttttgaaat caagaaaaat caatttgata atgagatgaa
     3841 acgcctagac agtatcaaac tcaagccagt caaggaaacc aatgctaagg ttgaggaaat
     3901 gggcttcaag ccgttgacag atgcggtgac agccaaagaa ttccttcgcc gtccagaagt
     3961 ttcttaccaa gatgtggtgg ccttcatcgg accagctgca gaagacttgg atgacaagat
     4021 tatcgaattg attgaaacag aaatcaagta cgaaggctat atttcaaaag ccatggatca
     4081 ggttgccaag atgaaacgta tggaagaaaa acgcattcca gccaatattg actgggatga
     4141 catcgattct attgcgacgg aagctcgtca gaagttcaaa ctcatcaatc cagaaaccat
     4201 cggccaagcc agccgtattt cgggagtaaa cccagcagat atttctattt tgatggtgta
     4261 tctggaaggt aaaaatcgta gtatttctaa aactcttcaa aaatcaaaat gatacgtcgt
     4321 cggcttctta cgaatgagtt caaagcttgg ctttgattca tctccagcct cccatagttc
     4381 cccgaactat gggagctaac tcaagttatg cattttccta gccttctggt ctgattttca
     4441 ttgagtttta atctcaaaag aaagcataga gaaaaacagc tccgaagacg gagctgtttt
     4501 gttgacttgt actcaatga
//
LOCUS       DAVBOM010000089         4347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBOM010000089 DAVBOM010000000
VERSION     DAVBOM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.090"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(60..659)
                     /locus_tag="VQ878_002048"
     CDS             complement(60..659)
                     /locus_tag="VQ878_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3096326.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(661..1758)
                     /locus_tag="VQ878_002049"
     CDS             complement(661..1758)
                     /locus_tag="VQ878_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3096327.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLVYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(1758..2495)
                     /locus_tag="VQ878_002050"
     CDS             complement(1758..2495)
                     /locus_tag="VQ878_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3096328.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(2497..3381)
                     /locus_tag="VQ878_002051"
     CDS             complement(2497..3381)
                     /locus_tag="VQ878_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3096329.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(3368..3562)
                     /locus_tag="VQ878_002052"
     CDS             complement(3368..3562)
                     /locus_tag="VQ878_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096330.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLCQFIRGALEFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(3559..3765)
                     /locus_tag="VQ878_002053"
     CDS             complement(3559..3765)
                     /locus_tag="VQ878_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096331.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1421 a          963 c          701 g         1262 t
ORIGIN      
        1 tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat attatatcat
       61 cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc agcatccagt
      121 tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta aagctgatct
      181 gcgatttctt ggttggataa gccccgggcg attcccttta aaacagcaat ctcttgttct
      241 gtcaacggat taggatgcgt catcaccact tccatcaatt caggcgaata ctccttgcgc
      301 ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttctttc tttcaagaca
      361 taagcatcca ctccagcctt gaccgcacgt tcaaaatacc ctggacgctt gaaggtcgtc
      421 accacaacca cctttgtttc aagcctttct gatcgtatcc actccaagac ttcaagacct
      481 gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt ttctaatagt
      541 tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg ttgaagcgtg
      601 agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa tactttcatc
      661 ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt tctgactgat
      721 tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga gctcatctcc
      781 ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt ccttctctgt
      841 ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat tggtcaccaa
      901 ctcaagcaaa atcatagaag ccattgactc cacatcctgg gtcaagctag ccttgtctaa
      961 gtgattctca acttgaacct caattccagc aatttctaac atctttttca cagtctctag
     1021 ttcggatgtc aaagttctag acttaagatt ttccacaatg gttcgcactt cattcatgga
     1081 atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat aagcctccat
     1141 ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg tatgccccag
     1201 actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca atagatttat
     1261 ctgggcattt tgcttaacct gtgcttcttt caaatcctcc acaattcgaa tccgaaccaa
     1321 gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagacta gaaactcaac
     1381 ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa gaagaaaagt
     1441 ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga gattggatag
     1501 gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa ctacataagt
     1561 cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta aaacacccaa
     1621 atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc acccagtcac
     1681 tacaggtagg atggggaaaa ccataaaaat taaactgatc caaaacatat aatgtatgct
     1741 tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat ggtcaaacca
     1801 aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat gccaccctca
     1861 tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt acctactact
     1921 tgcatccagt ctggaaataa agaaatgggc atccagagtc cgcctaaaac agccaatcct
     1981 agataaagaa gattgcccac aacagacatc agctgactag ttggtaagag agtcaaggtc
     2041 aagccaagtg ctacaaaagc aatactcccc acaatcagca aaatcgcagc tccaacccat
     2101 tttactagag gcatgtctac acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt
     2161 gagaccaaat aatcaaccag catacttgtt atctttgata gataatattc taccatattt
     2221 acagggctat gacgcaatgt tttctgccag ttgttcatct tatcggtatg taaaacagct
     2281 ggaaatgaga ggatagttgt cgacatcatg gaaaaggcag tcatggagat gaggtaatca
     2341 cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa aaataaatag
     2401 aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt ggtcaataaa
     2461 aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct tctgcgtctc
     2521 ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca tcctacatcc
     2581 tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt gtaaagaatc
     2641 ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct tgtaagctat
     2701 aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg tcgtatctcg
     2761 aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca cttcctcaat
     2821 ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga caatttccca
     2881 aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa aaacaatctt
     2941 tggtcgccca attaaggtca agacgaaaga aaagagacgc ttttgaccgc ctgataattt
     3001 ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa tttcctgatt
     3061 gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa cttttaattt
     3121 ctgaacgatt acattttctt gagggaggta agccctagta tagtctaact tagaactcgt
     3181 cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc caagcaaaca
     3241 atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac attcaccatc
     3301 gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct tactcaattt
     3361 ctcaacttta accaccgtca tgagactctc ctttcaacca ctccattccc atagggaaaa
     3421 cgacgaaaat cataaatcca aactccaaag caccacgaat gaattggcaa agcaaggctt
     3481 gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg ccgataaaga
     3541 aatagatgat ccctctcttc attcttcaaa ctcctttttc acatctctga ctaatttcaa
     3601 accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc aaggaaaatg
     3661 gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg ctactactaa
     3721 actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat actacaatta
     3781 tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg acaaatgtca
     3841 taaaaaattc tgttcaaaac aagcaagata cattatacaa taaaacacaa tcagaaaaat
     3901 ctaaggcaac ttcctcaaaa gagatatcaa actcaattca caccataatg taaactaata
     3961 cttatttaaa atcaaaaaga gtagaaattt ttatcagaca aacacatata tagtgtattg
     4021 aatctataac agtaggcctt aaatactaaa atatttctat aaattaattt aactttcctg
     4081 atagagctgt tcatatctta tttcaattct ctatattata cgttgaacaa aacccttcta
     4141 ttgctttctt aaaaatttat aagagttata aaatctgtta aatttcaatg tgtataccta
     4201 aactacggta tttattgaaa agactggaga caaaaagtat acgctgccaa aatgaattac
     4261 tgaaaatcaa aaaagagaga accaaactga ttccctctta atgtatataa tatctagttt
     4321 taaaaataca cactcacata tctctgt
//
LOCUS       DAVBOM010000090         4237 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBOM010000090 DAVBOM010000000
VERSION     DAVBOM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.091"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(12..1301)
                     /locus_tag="VQ878_002054"
     CDS             complement(12..1301)
                     /locus_tag="VQ878_002054"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET3096332.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1398..2627)
                     /locus_tag="VQ878_002055"
     CDS             complement(1398..2627)
                     /locus_tag="VQ878_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET3096333.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SILCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFFDNS"
     gene            complement(2820..3671)
                     /gene="rgg"
                     /locus_tag="VQ878_002056"
     CDS             complement(2820..3671)
                     /gene="rgg"
                     /locus_tag="VQ878_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET3096334.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3795..4136
                     /locus_tag="VQ878_002057"
     CDS             3795..4136
                     /locus_tag="VQ878_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3096335.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1346 a          884 c          834 g         1173 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataaaatcct agtttttcaa agatttctga gaagttttgg
       61 ctgattgtct caagtgacac ttgcacttct tctcgggttt ggttgttctt gactgtcact
      121 tgtctgcttt cgacttcgct ctctcctagg gtgatgaggg tcttagccgc aaagacatcg
      181 gctgacttga actgagcttt gagcttacgg ttgaggtaat cacgctctgc tttgaaacct
      241 tgttggcgaa gagcttggac tagttctagg gctttgacat ttgctccatc acccaagact
      301 gcgatataga catctagggc attttcgata gggagggcca cgccttgttt ttcaaggatg
      361 agaagcaggc gctctacacc aagcccaaaa ccaaatccag cagtttcagg gcctccaaag
      421 taagcaacca aaccatcgta gcgaccaccc gcacagactg tcaagtcatt gccctcaatc
      481 tctgtgataa actcgaaaat ggtgtggttg tagtagtcca gaccacgcac catattggta
      541 tcgatgatgt aatctactcc aagattttcc aacatctgac tcacagcatc aaaatgagtt
      601 tggctttctt catcaagaaa gtccaagata gacggcgcat tctctactgc caccttgtct
      661 tctttttcct tagagtccaa gacacgaaga ggattttcct ccaagcgacg ttggctatcc
      721 ttagacaagg tctccttgag cggtgtcaaa tagtcaatca aggcttggcg gtaggctgca
      781 cggctctcag gatttccaag agtgttgagg tgcaatttga caccttgaat accgatttcc
      841 ttcaaaaaat gggctgccat aacgattgtt tccacatcgg tagctggatt gctagaacca
      901 aaacactcaa caccaatctg gtggaattgg cgcaagcgcc ctgcctgtgg acgctcataa
      961 cggaacatag gtcccatgta gtagaacttg cttggctttt gcacttctgg agcgaagagt
     1021 ttattttcca cataggcacg gacaacgggc gcagttcctt ctggacggag ggtaatatgg
     1081 cggtcaccct tgtcatagaa atcgtacatt tccttggtta caatatctgt tgtatctccg
     1141 acagagcggc tgataacctc gtaatgctcg aaaataggcg tacgcacttc tgcgtagttg
     1201 tagcgcttga aaatttcacg ggcaaagccc tcaacgtact gccacttagc agactcagca
     1261 ggtaaaatat cctgcgttcc ttttggtttt tgtaatttca tagggaatcc tctttaaact
     1321 taatagtctt attttaccat aaatagaggg attaaaacag taagaaaaaa attaggattt
     1381 agatatcatt tttgagatta agaattgtca aaaaaaatag ctagcaagga aagaccaaca
     1441 aatagcatcc aagtcaactg tatattccat acggctacta gtgaaaaaca agctgttccc
     1501 acaggtatgg ataaggtaaa caatagacct aaaaaattac tagtacgagc tagaacctct
     1561 ggagctagat ttttcatgag catggcacta atctttggtt gaactttacc agacacatac
     1621 agagtaaaga agagaaatag caaaccaagc acgacttgat tgaataaatt agccaaacca
     1681 actagactaa gccctacggt cgcccacatc atcaatctag gcaaggactg cttcccaaaa
     1741 taatcattgc ccgtaaggct actgatgatg actgctacta aaacacagaa ttgattgata
     1801 aatagtgcct ctgtataaga aaaattcaag agagaatggc tcaaaaagaa gatattataa
     1861 attccaccca aagcgccacc caaggaatta ataagcaaga cagcaaagag cataaaacca
     1921 aagtttttct gtccactttt aagaaaaacg agacgtaaat ttcggtaaat tgttaggaac
     1981 tggtctttga tagaaagctt ctcatttttt aagttttcac catcagcaga tgacattgac
     2041 aggctcaatt tgctttttcc taaaaagagg atagtggctg atactaggaa aaagcaggca
     2101 ttgattcccg caacgagaga aaaattgttg accgatagag ctaagagcca gactccgaaa
     2161 gcttgaccac caatagctga aatataggtg atgaactgtg aaaaagaata agcctccatc
     2221 agatcatctt cagctacttt ttccttaata agaggcatac gcaggccacc tgcaaaatca
     2281 ctgatgatat cactaatgac attgatcaaa cacaggatag aaaaggcaaa gagactagct
     2341 tgctgaacaa ctagggctgc tagaaaaaat agaaccgcct gaaacaaacc gctatagacc
     2401 atccatttga ccttgtccct cgtgtaatct gcccgaatcc ctgcaaaaac tgtaaagagg
     2461 gtcggaagaa tcatgacaat attcgccata gcaacagcaa aagatgcttg tgacaaggtc
     2521 gatgcataga cgataaagac caggttgaaa atcgaagcac caaaagcatt gaagaagcgt
     2581 gataaagtca aaattctata agctggattt ctaaacaata gtttcataga taatctccct
     2641 tcttgttcga acctctatat gaagtatgac tatagtatag cacttagaaa tttgagaggg
     2701 agaactcttg aatatatgca acaaataaaa tgagcaaaaa gaaacgatag aacttttgta
     2761 atgacctgag agagggcaat agttctatcg cttcaaattt tttcttggtt tgcagatatt
     2821 caacattcgg tcgtatttct atagtattcg gcagatttat tacagccaag catctcaaaa
     2881 atacggacag catcctccat ctttttctgg ccttccttga ctctaccttg cttgctatca
     2941 aggagacctt ctgcccacag ataaacaatt cggaaatagg tctcattttc cttgtagaaa
     3001 tgctcttcga taacacgttt aaaataatag gcattggtaa attcttcaca ctcaatacta
     3061 gctaaaaagc cgttcaatag tatagtatga aaaaggtttc gattgccaga catttccatt
     3121 agaaaatcag atttacgtac catttctcgt acatatctag taaaaagaga aacagataaa
     3181 aatggagaac tgactgaaaa taaattgagt tcatagattc cccagatctc ggtagaaaac
     3241 aaataatcat gaaggacttt tccttcctct gctgttaagt ctaccctttc atctatgctc
     3301 ttcatataag acttgataat aatggcattt agaatatgtt tctgtttgtt gtgagaatgg
     3361 gcatgctttt gatactccct gcgatataag tcctcaagag gtgctatatt ctttggttcc
     3421 aagacatctg taatttcttt tctcaactca gaatctgtat catactggaa acctctcgcc
     3481 agaaagagga tctcctccac actggcagat atattttcca gagcaaatag aaacttttcc
     3541 accgaaagct cactctgacc tgtttcaaaa cgggacaaca tagacggcga aaattgtcct
     3601 ccggttgctt gtctcagtga gatatttctt gactctcgta attgtctaaa gacttttcca
     3661 atctgctcca tagacttccc cttgattccg tattttcttc attttatcat atttttcaga
     3721 aaattaatca aaagcttgcc aaattgtcag aattatgaga aaatagagga tatttatcac
     3781 atggagggac tgctatgaga gacgatatca aaatcaatga ccgtgctttg gccttgcaag
     3841 accaaattat cgaaaaacta gagaaagttt ttgatacaga tgtggaattg gatgtttaca
     3901 atctaggtct gatttatgaa atcaatctgg atgaaacggg gctctgcaag attgtcatga
     3961 ccttcaccga tactgcctgt gattgcgccg aaagcctgcc tattgaaatt gtggcaggtc
     4021 tgaaacaaat cgagggtatc aaagatatca aggttgaagt tacctggtcg cctgcttgga
     4081 aaatcacacg aatcagtcgc tatggccgta ttgcccttgg actaccacct cgttaagcag
     4141 gccaatcact tttaaagatg aaaaaagcaa gccgaaaatg gcttgctttt tgatactcaa
     4201 tgaaaatcaa agggcaaact agaaaactag ccgcagg
//
LOCUS       DAVBOM010000091         4193 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBOM010000091 DAVBOM010000000
VERSION     DAVBOM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.092"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            720..1712
                     /locus_tag="VQ878_002058"
     CDS             720..1712
                     /locus_tag="VQ878_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3096336.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINKEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VQ878_002059"
     CDS             1714..2532
                     /locus_tag="VQ878_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET3096337.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VQ878_002060"
     CDS             2534..3319
                     /locus_tag="VQ878_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3096338.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VQ878_002061"
     CDS             3358..3636
                     /locus_tag="VQ878_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET3096339.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VQ878_002062"
     CDS             3621..3818
                     /locus_tag="VQ878_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3096340.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1171 a          717 c          904 g         1401 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gagtgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aattttacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccagaaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaataa agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactggatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtagcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttatttgaca tctattctca
     3841 gagtgctata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg act
//
LOCUS       DAVBOM010000092         3518 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBOM010000092 DAVBOM010000000
VERSION     DAVBOM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.093"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..73
                     /locus_tag="VQ878_002063"
     CDS             <1..73
                     /locus_tag="VQ878_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HET3096341.1"
                     /translation="TVPVIAAIAKKLKEIEEKDESIK"
     gene            57..506
                     /locus_tag="VQ878_002064"
     CDS             57..506
                     /locus_tag="VQ878_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096342.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWKVSHD"
     gene            499..879
                     /locus_tag="VQ878_002065"
     CDS             499..879
                     /locus_tag="VQ878_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096343.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
     gene            892..1125
                     /locus_tag="VQ878_002066"
                     /pseudo
     CDS             892..1125
                     /locus_tag="VQ878_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            1128..1715
                     /locus_tag="VQ878_002067"
     CDS             1128..1715
                     /locus_tag="VQ878_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3096344.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWNLSVYVLFFL"
     gene            1845..2435
                     /locus_tag="VQ878_002068"
     CDS             1845..2435
                     /locus_tag="VQ878_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET3096345.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVTEGKIDA
                     EEKGLYRLPDIYLDEWFVIQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEIERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNQIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            2435..3271
                     /locus_tag="VQ878_002069"
     CDS             2435..3271
                     /locus_tag="VQ878_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET3096346.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIDIFEEILCSKTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AKKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
BASE COUNT         1222 a          513 c          641 g         1142 t
ORIGIN      
        1 aaccgttcct gtgattgccg caatcgcaaa gaaattaaaa gaaatagagg aaaaagatga
       61 aagcattaaa taaagaatca atactagatt gtgatgaatt agaaacagaa ttacatgatg
      121 cagaaatcaa acagctggat gaacaattat ttttgatgcc caattatcca tgtgagtttg
      181 aagtaacatt tttagatgat taccataaaa aacacaacta cccactattt tacgagtcct
      241 atcttcaaaa cgttatggaa ttccttgaaa gtcaagacat aaagaatggg gttgatgcct
      301 ttgtagatga tcatcaaaat ctcgtttttg ttttatatgg acaaggctat cgagcagagg
      361 gaaaagaggg aatacttaca actcaagtaa ctgtaaaagc ttatgatgaa gacaagaaac
      421 cgattaactt cgcaaattta ttagattcct taatcgtctc agaatatcaa atggaaccga
      481 atctttggaa ggtctcccat gattgatctc tatctaagta aaaatagcca aagaaatcaa
      541 cttcttttgg atttctttca aaagtatggc atagaggtca ctcctcattc tatttctgaa
      601 atgacaaagg acaaattaat tgaaatgatg agctattctt cagattgttt tgagtttcta
      661 tctcccaatt tattacgatt taagaaccgt gacaatctaa gattaacgga tttcattgaa
      721 atgatattaa aaaatcctga actatgcatc aggcttcctc ttgcggtttc aaataagaga
      781 gtttatccaa atctgaattt ggaagaggct agagctctat tgccaagaga tacgaaacaa
      841 ttgatttaca tggcacaaac acattattta tctagttaaa ggagaagcaa tatggctgaa
      901 cgattttggg agaacttgtc cattattttg gctgaaagaa atattagctg aattgagtta
      961 accagaaaaa tgtttgcggg agagtttcac tatccaagtg aattgaatcg tttgtatcaa
     1021 aagatacgcc actacaagat ggaacaacga atgcctcaaa gtccatgggt agaaaggatt
     1081 gtgcaggtat tagatttaga ttatgaagat ttatttcgga ggtaactatg aaaagaataa
     1141 ttccagttta tatattccaa caagtaaatg tcttattggt atccctatac ttactgaaat
     1201 tgctttgtat tggtgagtta accatactac agattctcta ttgtgcgtcg ctcatttctt
     1261 ttttatggat gtatggtcaa cgaaaacaag tggtcaaggt caatatgaaa actaggatga
     1321 aatggcttgg tattggattc gttagcctac tgattataag cctatgtttt agtctgattc
     1381 atgctcaagg aaccacgaat caagcaaact taattggcct tcaacatcag gttccttggt
     1441 tttcattttt attgttctta atcaatgcga gtatggttga agaatttctg tatcgagaaa
     1501 ttttatggaa cttggtcaga aaattagata ttcgagttgc tttgacaagt gttttatttg
     1561 ccttagtaca tcatccagga accattctag cttggtgttt atatgtttca cttgggatct
     1621 ttttagggat ggtgcgctat aaatcggact tatggggaag tatgggtcta catttggtgt
     1681 ggaacctatc agtctatgtc ttattttttc tttaataata gctggtctgt cttacgtatg
     1741 gattaatttt gaaataaaaa aactaaatga attgatttta aagaaataaa atgctaacat
     1801 atatagaaga tgttagcatt ttatttctaa gaaaggagaa tggtatggtt gataaaagag
     1861 agaaactgat gaactctttc aatcagtatg gttttttaac ttttaaacaa gtaatagatg
     1921 aaaatttaca ctacaaaacc ttattaaaaa tggttacaga aggaaaaatc gatgctgaag
     1981 aaaaagggtt atatcgctta cctgatattt atttagatga gtggtttgtc attcagtatc
     2041 gatttccaaa aggaatcttt tctttggaga cagcactttg gttacatggt ttatctttga
     2101 ctatcccttt taacatgaca atgagttttc cttatggtac gaataccaaa aacattaagg
     2161 aagcagatat atgtcctatt atcttacgct ctcactatag tgaaggaatt attgaaatag
     2221 agcgtcttcc tggtcaattt attaaagttt atgaaattga acgagttttg gttgaatgtc
     2281 taagaccagt tcatcaggtg gatcttcaaa ttattgcacc agcgtttaag aaatattttc
     2341 aacagaatca aattcattta cacaaattat tttattatgc ccaactattt aaagtaactg
     2401 ataagttaca atcttatacg gaggtgctat cttaatgttt tcaaatgcga atagctttaa
     2461 agcaaaaatc aaaaatattt caaaagataa gggaattcca gctcaacaag tacaacaaca
     2521 ttatttaatt gagcaagtgt taaagctgat ttctactagt tcttatagag attccttcat
     2581 tgtaaaagga gggtatctaa taggtcaaat gattggacta gataagcgaa ccacaatgga
     2641 tttagatgtc actctgaagg gaaccgaaat gagcagagaa aatttgattg atatctttga
     2701 agagattctt tgttctaaaa ctgatggttt ttcattttca gtagataagc tagaacctat
     2761 tcgccaagat gatgaatatg gaggattttc attaaaatta aatgcaactt ttgatacatt
     2821 aaaggaggtt gtttttattg atattactac tggtgataag atcacaccaa gagaaattac
     2881 ttattcaatg acttctatct ttactaatga aagcatcaag atatggacat ataatctaga
     2941 aactgtactt gctgaaaagt tagaaacaat cattagtagg ggattagctt caacacgccc
     3001 acgtgatcga tatgatcttt tcaccttgta taaacttaga aaagaagaga ttaatcttga
     3061 agtattaaaa aatgcacttg aaaatacagc aaaaaaacgt aaaagtaaag atactattta
     3121 taattgggaa gaacaagtga gaggaattga aatttctgat tatcagaaag agctatggat
     3181 tcgttatcaa cgccaattta agtatgctaa agatatctca tttgataact ctgttcaggt
     3241 tattagggaa attatgcaac aaatatttta gtacaaaagt aactcattcg taaagcagtg
     3301 agttgctttt tttattccaa caacctcaaa catgtgataa aaatttcaac tactcttatc
     3361 tataataaag ctacctgttc tttgaaaatt gaatccactc cgtcttgatt agcgtgcctg
     3421 tgtaagtagg gaatgagagt atttccctgt gaagggcaac tggcacaaga cgtgtgtgag
     3481 aattttctaa cagacacgga gtttatcgtt tccagact
//
LOCUS       DAVBOM010000093         3140 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBOM010000093 DAVBOM010000000
VERSION     DAVBOM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.094"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            194..397
                     /locus_tag="VQ878_002070"
     CDS             194..397
                     /locus_tag="VQ878_002070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096347.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(484..744)
                     /locus_tag="VQ878_002071"
     CDS             complement(484..744)
                     /locus_tag="VQ878_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096348.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(799..1143)
                     /locus_tag="VQ878_002072"
     CDS             complement(799..1143)
                     /locus_tag="VQ878_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096349.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            2182..>3140
                     /gene="ltrA"
                     /locus_tag="VQ878_002073"
     CDS             2182..>3140
                     /gene="ltrA"
                     /locus_tag="VQ878_002073"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET3096350.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLS"
BASE COUNT         1078 a          570 c          639 g          853 t
ORIGIN      
        1 agtattagaa aacaattatg ttgatagagc ttgggcaaga gcccaatttc agcaaaaaat
       61 gaagtaaatc ttctcataat aaaacgcatc atatcaagca cgaaaattcc acgaggtcaa
      121 ctacagtcag aaagctgaac aacaagccaa aacgcccaaa aaaggcggca aaaagcaagc
      181 acctgcaagc aacgtgccga aatggtcaaa tcctgattat gtcaacgaat tagacccaaa
      241 aatcgttgat atgctagtag aatttcacaa gtcacaaggc actttggaaa ctcccgaggc
      301 gcaagcagaa atcgcccaaa aacgtgaaga aatcgagcaa aggagagctg agcttgagga
      361 taaaaaacaa gagcttttga accgcttgaa caaatagagt ttcgcaagta ttatgcttac
      421 aaattacttg agcaattaac taaaatataa accctgcctt tatatctagg cagggtttat
      481 attttagaaa ttcacgtagg ttgttacggt ttttacatac ccagtatagt ttgagtttct
      541 atagtattca gtgataaact tccattttct ttgagcaaca tggatataag tacttgttat
      601 gtagtatgga tatgggcttt gtgaatccaa gtaagactga taagcttgta taccaaaata
      661 tgctccacca attattgcac cccatggacc ccccaataaa gcacctatcc taccaatcat
      721 ataactgatt ccagcaccag tcatgaagtt agcgaatgtg ttagcttgtt tattcccatg
      781 tattgtgttg acgtaatttc aaacattagg atcgtatgat ctaaaagata tatttaggtc
      841 gatttcattc ttttgataag ccatataaaa tgccccattg atatagacgc cgtcagcacg
      901 tcgttcaata gtgtctacac ttccatctgg attgacaacc tcaagaactt catcgcttaa
      961 aatatttact tgcgtatctc cgaaccgcac tgatgagcca ttctcaaact gagcctcacc
     1021 agatacaact ttagagtttg ccgataagct atcatcagca aaaacaacaa gcgacgggga
     1081 aatgctagac atacagaaaa cagacataac tagcaaacac atgcatttaa acatcttaga
     1141 cataacggaa actcttttgt atttttgatt tttttcaact tttattatac aataaaacca
     1201 aataaaaaga aagcggtaac aatatgctta atgcgaaaat tttttatata tttttatgtt
     1261 tgatcgttat cgaaactaca ggcttgttgt tgttgaaaag aggtctcgaa atgggttatt
     1321 tagacacaga agctattatc ctcgcagttt tttcatttgc tttttacaac ctatgttcat
     1381 tcgcttgggt ctgctctaca ataaaaaaca ataaaaaata aatagacgta ttttcaaaaa
     1441 aaaaaaaaat gcatatttat cttagcaaaa tgacgattta aatcgtcgtt tttttgtagt
     1501 acgacgggca tgtcgtatat ctgaggtgta agtcctcggt gggcacctgc taccggtgaa
     1561 cccaatagcg attcccaagc ctgactatcg tgaggtagca gggagaggaa gggatagcga
     1621 aatcgtggct ctacgaacag gaacgtgata gtaaggcgta tatagcggat aaggaggctt
     1681 caaactctaa agtccaaaaa ggtagtcgta acctatatgt gtaaatcacg agagtaattg
     1741 aattcggact aaggtttgtg tgaaaaagat aaatctttct agagtctaaa gactctgcgt
     1801 cagatttcct attttcactg taacctttta acgtcctcat atcttgtata aacgaggaaa
     1861 gatgtacgac ttatcccgtg aggtttcatg agcgctgaaa gcgtagtaac aacgaatcat
     1921 gagaagtcag ccgagcccat agtagtgagg aaacttctgt agtggaagtg gagcgacggg
     1981 gtgaatactc aaacagtctg gggagagact gtttgaggtc tgtcgctaga aagagaaaac
     2041 gacagatcga agtaatccta cttcacttgt gtctgtaaaa tgagtggtct gatagaactg
     2101 gactttgaca cgtaatgact agatgaaggt tcaccaatat aagatgtccc tcaggcacca
     2161 aaacaagaaa ggaataggca catgtcaaaa ctgctagata agatattatc acgcgaaaat
     2221 atgctggaag cctacaatca agtaaaatcc aataaaggct cagctgggat tgatggaatg
     2281 actatcgaag agatggataa ttatctcaga caaaactggc gcttgactaa ggaactgata
     2341 aaacagagaa aatataagcc tcaaccagtt cttaaagttg agatacctaa accagacgga
     2401 ggcatccgtc aactaggaat tccaacagtt atggatagaa tgattcaaca ggccattgtc
     2461 caagtcatga gccccatttg tgaaccccat ttctcagata cgagttatgg tttcagacca
     2521 aataggtcat gtgaaaaagc catcatgaag ctcttagaat acttaaatga cggctatgag
     2581 tggatagtgg atatagacct agagaaattt ttcgatacag ttcctcaaga tagattgatg
     2641 tccttagtac ataacattat cgaagacgga gatacggaat ccttgattcg taagtatctt
     2701 cattcaggtg ttatcattaa tggtcaacgt tataaaacac tagttggtac accacaggga
     2761 ggaaatttat ctcctctctt atccaatatc atgcttaatg aattggacaa ggaattagaa
     2821 aagaggggac ttcgatttgt gcgctacgca gatgattgtg tgattacggt cggaagcgag
     2881 gcagcctcta agcgtgtgat gtattcagtc agtcgtttta ttgagaaacg gctaggtttg
     2941 aaagtaaaca tgaccaagac taagattacc agaccaagag agttgaaata tctaggtttt
     3001 gggttctgga aatcatcaga tggttggaaa agccgtccac atcaagatag tgttcggaga
     3061 tttaagttta aattgaagaa actaacacag aggaaatgga gtatagacct aacaagacgt
     3121 attgagcaac tgaatttgtc
//
LOCUS       DAVBOM010000094         2909 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBOM010000094 DAVBOM010000000
VERSION     DAVBOM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.095"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(64..1005)
                     /locus_tag="VQ878_002074"
     CDS             complement(64..1005)
                     /locus_tag="VQ878_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3096351.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ878_002075"
     CDS             complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ878_002075"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET3096352.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRNLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          846 a          688 c          578 g          797 t
ORIGIN      
        1 aaccatatat acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa
       61 tcactaatta tctatctcaa caaatcttcc tagaatatga acattttccg agacagagac
      121 aaaggagctt ggatccactt gtgtcataat ctgtttaaat tcattaaact ctgcacgtgt
      181 aatgacagtg attaaaactg cctttctctc gtgattatag gttccttctg catcatggat
      241 catggttgct ccgcggtgca attttttatg gattttttca attaccttct ctggatgatt
      301 tgtcacaatc atggcctgca tacgcttttg cttagtaaag actgcgtctg tcacacgact
      361 agagacaaag atggtaatca tagaataaag agcgtatttc caaccaaagg tcaaacctgc
      421 tatcagcatg atagttccat ttaccaagaa agaaatacta ccgacattct tacccgtttt
      481 cttgcgaata gtcaggctga cgatatccgt cccaccactg gagatattgt ttcgaagagc
      541 aaaaccaatc cccaaaccca taacaacacc cccaaaaagg gcattgataa tgggatcctc
      601 cgtcaaggtt gccacaggga caaactggat aaagaaggaa ctcatagata ccgtgataaa
      661 ggtaaagacg gtgaacttat ggccaatctg ataccaagct aagaccatca aagggaagtt
      721 aatggcgtaa aagcttagcg aaatcggaat atgaaaacca aaccagtgat tactcaaggc
      781 agagataatc tgtgccagac ctgttgcacc actcgaatac acatgccctg gttggaaaaa
      841 gaaattaact gctactgctg ataaaaaacc atagaccaga gaggccgaaa tcttctcatc
      901 atacttttct cgagagatac tttgtaagac acgtaaaatt tttatctgat aagcaaagcg
      961 gcgcagataa tagcgccacc gcttaattcg ttttgtttgt ttcatcttct tctacttgta
     1021 agctgagttc ctctagttgt ttgagagcga ctgttgatgg agcttgtgtc attgggtcag
     1081 ttgccttgtt gttcttagga aaggcaatga cttcacggat attttcttct ccagcaagca
     1141 acatgacaaa acggtcaagc ccgatagcca aaccaccgtg tggtgggaaa ccatagtcca
     1201 tggcttcaag aaggaaacca aactggtcat tggcttcttc agttgagaaa ccaagagcct
     1261 tgaacatgcg ttcttgaagg tctttttggt tgatacgaag gctaccacca ccaagctcat
     1321 aaccgttcaa gacgatatcg taagcaatgg cacgaacctt agccaaatca ccttctaatt
     1381 cgtgagcagt cccttcctgt ggaagtgtga atggatggtg ggcgctcatg tagcggcctt
     1441 cttcttcaga ccattcaaac atcggccagt caaccaccca aaggaagttg aacttatcat
     1501 tatcaatcaa gccaagctct ttagcaatac gtccacgaag ggcacccagt gttgcattaa
     1561 ccacttcaag cgtatccgcc acaaagagaa ccaagtcctt atcttcaaga gcaagcgctg
     1621 ttgtcaattc ttcttggata ccagtcaaga acttggcaac tggtccgttt aattctccat
     1681 caaccacctt gacccaagca agacctttgg caccatactg tttggctact tccgtcatct
     1741 tgtcgatgtc tttacgtgaa tagttgtccg cagctccttt gaccacaatc gcttttacag
     1801 caggtgcttc tgaaaagact ttaaagtcta cacctttgac cacttctgtc aagtcctgaa
     1861 gcaacatgtc aaaacgagta tctggcttgt cagaaccgta aagagccata gcatcatcgt
     1921 atttcatacg agggaacggt agcgttactt cgatgccttt tgtttccttc atcacgcgcg
     1981 cgatcaagcc ttctgtaata tcttggattt ctttctcagt aaggaaggac gtttccaagt
     2041 cgacctgagt aaattcaggc tggcggtctc cacgcaagtc ctcgtcacgg aaacatttaa
     2101 cgatttggta gtaacggtca aaaccagcat tcatcaagag ctgtttcgtg atttgtggac
     2161 tttgaggaag agcgtaaaaa tgccccttat taacacgaga cggcactaaa taatcacgcg
     2221 ccccttcagg cgttgactta gaaaggaatg gtgtctccac gtcgataaac tccaactcat
     2281 ccaaatagtt gcggatagag tgggtcacct tggcacgaag tttaagattt tccaacattt
     2341 ctggacgacg aaggtcaagg taacggtaac gcaaacgtgt atcgtcattt gcctcaatgc
     2401 catccttaat ctcaaatggt gttgtcttag ctgtgttaag cacaataaga gctgtcacgt
     2461 ttaactcaac cgcaccagtt ggcaacttat cattggcttg ctcacgcgca gcgacctgac
     2521 cagtcacctc aataacaaat tcgctacgaa ggctttcagc tgttgccata acctctgcag
     2581 atactttttc agggttgata accaactgca tgattccttc acggtcacga agatcgataa
     2641 agatcaaacc accaaggtta cgacgacggc caacccatcc tttcaaggtt atttcttgtc
     2701 cgatgtgttc ctcacgaaca cgaccagcat acatactacg tttcattatt tctctcctct
     2761 tttattctgt tactatttta ccataaaagc gcaggctctt catgaaaatc atcagaaaag
     2821 tttgccagtc tttaaaagtc aggtgaaagc cctaaaaatt agcgctaatg ctcttcgaaa
     2881 atctcttcaa accacgtcag cgtcgcctt
//
LOCUS       DAVBOM010000095         2853 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBOM010000095 DAVBOM010000000
VERSION     DAVBOM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.096"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            108..824
                     /locus_tag="VQ878_002076"
     CDS             108..824
                     /locus_tag="VQ878_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET3096353.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            1133..1558
                     /gene="rplK"
                     /locus_tag="VQ878_002077"
     CDS             1133..1558
                     /gene="rplK"
                     /locus_tag="VQ878_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET3096354.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1766..2455
                     /gene="rplA"
                     /locus_tag="VQ878_002078"
     CDS             1766..2455
                     /gene="rplA"
                     /locus_tag="VQ878_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET3096355.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          955 a          535 c          642 g          721 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctattaaaag attagtcaaa
       61 cgtttatcat cagaagtaga taaactatta gaaataaagg agtagaaatg aagaaaagat
      121 accttgtcgt gacagccttg ctagccttga gtctagcagc ttgttcacaa gaaaaagcaa
      181 aaaatgaaga tggcacagct aagacagaac agacagccaa agctgatggg acagtcggca
      241 gtaagtctca aggggctgcc cagaaaaaag cagaagtggt caataaaggt gattactaca
      301 gcatccaagg aaaatacgac gaaatcatcg tagccaataa acattatcct ttgtcgaaag
      361 actataatcc gggggaaaat ccaacagcca aggctgagtt ggtcaaactc atcaaagcga
      421 tgcaagaggc aggtttccct attagtgatc attacagtgg ttttagaagt tatgaaactc
      481 agaccaagct ctatcaagat tatgtcaacc aagatggaaa ggcagcagct gaccgttact
      541 ctgcccgtcc tggctatagc gaacaccaga caggcttggc ctttgatgtg attgggactg
      601 atggtgattt ggtgacagaa gaaaaagcag cccaatggct cttggatcat gcagctgatt
      661 atggctttgt tgtccgttat ctcaaaggca aggaaaagga aacaggctat atggctgagg
      721 aatggcacct gcgttatgta ggaaaagaag ctaaagaaat tgctgcaagt ggtctcagtt
      781 tggaagaata ctatggcttt gaaggcggag actacgtcga ttaatactct tcgaaaatct
      841 cttcaaacca cgtcagcgtc gccttaccta ctgactgcgt cggttctatt cacaacctca
      901 aaacagtgtt ttgagctgac ttcgtcagtt ttatctgcaa tctcaaagct gtactttgag
      961 cagcctacag ctagcttcct agtttgctct ttgattttca ttgagtataa aaaataaact
     1021 tttctcttgc aattccagat aaatagtgta taatggatgg gtatgtgaaa aacatacttg
     1081 tgggaggtaa aaatctctaa ttaccgccaa aaccacaaag gaggatttaa aaatggctaa
     1141 aaaagtcgaa aaacttgtaa aattgcaaat ccctgctggt aaagctacac cagctccacc
     1201 ggttggacct gctcttggtc aagctggtat caacatcatg ggattcacaa aagagttcaa
     1261 cgctcgtaca gctgaccaag ctggtatgat cattccagtt gttatctcag tttacgaaga
     1321 taaatcattt actttcgtta cgaaaacacc accagctgct gttcttttga aaaaagctgc
     1381 aggtgttgaa aaaggatcag gtacacctaa taaaactaaa gttgctacag ttactcgtgc
     1441 acaagtacaa gaaattgcag aaactaagat gccagatttg aacgcagcaa acgtagagtc
     1501 tgcaatgcgt atgatcgaag gtactgctcg ttctatggga ttcactgttg ttgactaatc
     1561 aataacacag tagaaaatct cacagcagtc tattagttgc ttttcatact aggcaagtga
     1621 ctgaggcttg tacttgggta cagcaaggga gcttaaggcc gtaggaagag aaaaatagta
     1681 gactgaaaac ccgcaagact tcatcatttc gagaagtgac gtgggagatg aaaatcgatt
     1741 gaaccactta caaggagaat agaaaatggc taaaaaaagc aaacaacttc gtgctgctct
     1801 tgagaaaatc gacagcacaa aagcatacag cgtagaagaa gctgtagcac ttgcaaaaga
     1861 aactaacttt gcaaaatttg acgcaactgt agaagttgct tacaacttga acatcgacgt
     1921 taaaaaagct gaccaacaaa tccgtggagc aatggtattg ccaaacggta ctggtaaaac
     1981 ttcacgtgtt cttgttttcg cacgtggtgc aaaagctgaa gaagcaaaag ctgctggtgc
     2041 agactttgtt ggtgaagatg accttgttgc taaaatcaac gacggttggt tggatttcga
     2101 cgtagttatc gctacacctg atatgatggc tcttgttgga cgtcttggac gtgtccttgg
     2161 accacgtaac ttgatgccaa accctaaaac tggtactgta acaatggatg ttgctaaagc
     2221 agttgaagag tctaaaggtg gtaaaatcac ttaccgtgct gaccgtgcag gtaacgttca
     2281 agcaatcatc ggtaaagtat catttgaagc tgaaaaattg gttgaaaact ttaaagcttt
     2341 caacgaaaca atccaaaaag caaaaccagc tacagctaaa ggaacttacg taacaaactt
     2401 gactatcaca actactcaag gtgttggtat caaagttgac gtaaactcac tttaatcagt
     2461 agttaaagta atgtaaaaaa gttgaagacg ctatgtctca actttttttg atatacgacg
     2521 ggcatgtcgt atatctgagg tgtaaatcct cggtgggcac ctactactgg tgaacccaat
     2581 agcgattccc aagtctgact atcgtgaggt agcggattaa aacggtctgg ggatagaccg
     2641 ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa atcgtggctc
     2701 tacgaacagg aacgtgataa taaggcctat atagcggata aggtatctgg ctggggcgac
     2761 cactatcaat tatagtaaaa tgaaataaga gtaggacgaa tcgatcaggg cagccaaatc
     2821 gatttctaac aatgttttag aagaagagat gta
//
LOCUS       DAVBOM010000096         2663 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBOM010000096 DAVBOM010000000
VERSION     DAVBOM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.097"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            61..1887
                     /gene="glpO"
                     /locus_tag="VQ878_002079"
     CDS             61..1887
                     /gene="glpO"
                     /locus_tag="VQ878_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET3096356.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            1957..2661
                     /locus_tag="VQ878_002080"
     CDS             1957..2661
                     /locus_tag="VQ878_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3096357.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
BASE COUNT          736 a          544 c          640 g          743 t
ORIGIN      
        1 agattttcga agagtataat actggcagaa taaagcgatt tatttagaaa gtgtgtaaat
       61 atggaatttt caaagaaaac acgtgaattg tcaattaaaa aaatgcagga acgcaccctg
      121 gacctcttga ttatcggtgg aggaatcaca ggagctggtg tagccttgca ggcggcagct
      181 agcggtcttg agactggttt gattgaaatg caagactttg cagaaggaac atctagtcgt
      241 tcaacaaaat tggttcacgg aggtcttcgc tacctcaaac aattcgacgt agaggtggtc
      301 tcagatacgg tttctgaacg tgcagtggtt caacaaatcg ctccacacat tccaaaacca
      361 gatccaatgc tcttaccagt ttacgatgaa gatggagcaa cctttagcct cttccgtctt
      421 aaagtagcca tggacttgta cgacctttta gcaggtgtga gcaacacacc aactgcgaac
      481 aaggttttga gcaaggatca agtcttggaa cgccagccaa acttgaagaa ggaaggcttg
      541 gtaggaggtg gagtgtatct tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac
      601 atcaaacgtg ccaaccaaga cggtgccctc attgccaacc acgtgaaggc agaaggcttc
      661 ctctttgacg aaagtggcaa gattacaggt gttgtagctc gtgatctctt gacagaccaa
      721 gtatttgaaa tcaaggcccg tctggttatt aatacaacag gtccttggag tgataaagta
      781 cgtaatttgt ctaataaggg aacgcaattc tcacaaatgc gcccaactaa gggagttcac
      841 ttggtagtgg attcaagcaa aatcaaggtt tcacagccag tttactttga cacaggtttg
      901 ggtgacggtc gtatggtctt tgttctccca cgtgaaaaca agacttactt tggtacaact
      961 gatacagact acacaggtga tttggagcat ccaaaagtaa ctcaagaaga tgtagattat
     1021 ctacttggca ttgtcaacaa ccgctttcca gaatccaaca tcaccattga tgatatcgaa
     1081 agcagctggg caggtcttcg tccattgatt gcagggaaca gtgcctctga ctataatggt
     1141 ggaaataacg gtaccatcag tgatgaaagc tttgacaact tgattgcgac tgttgaatct
     1201 tatctctcca aagaaaaaac acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt
     1261 agcacatctg agaaatattt ggatccatct gcagtttctc gtgggtctag cttggaccgt
     1321 gatgacaatg gtctcttgac tcttgctggt ggtaaaatca cagactaccg taagatggct
     1381 gaaggagcta tggagcgcgt ggttgacatc ctcaaagcag aatttgaccg tagctttaaa
     1441 ttgatcaatt ctaaaactta ccctgtttca ggtggagaat tgaacccagc aaatgtggat
     1501 tcagaaatcg aagcctttgc gcaacttgga gtttcacgtg gtttggatag caaggaagct
     1561 cattacctag caaatcttta cggttcaaat gcaccgaagg tctttgcact tgctcacagc
     1621 ttggaacaag cgccaggtct tagtttggca gacaccttgt cccttcacta tgcaatgcgc
     1681 aatgagttga ctcttagccc agttgacttc cttcttcgtc gtaccaatca catgctcttt
     1741 atgcgtgata gcttggatag tatcgttgag ccagttttgg atgaaatggg acgattctat
     1801 gactggacag aagaagaaaa agcaacttac cgtgctgatg tcgaagcagc tctcgctaac
     1861 aacgatttag cagaattaaa aaattaagaa aaaataaaag aggtggaggg cagcattcct
     1921 tgtcgcccgt cccttctttt taatggagac agaaagatga tgaatgaatt atttggagaa
     1981 tttctaggga ctttaattct gattcttcta ggaaatggtg ttgttgcagg tgtggttctt
     2041 cctaaaacca agagcaatag ctcaggttgg attgtgatta ctatgggttg ggggattgca
     2101 gttgcggttg cagtctttgt atctggcaag ctcagtccag ctcatttaaa cccagctgtg
     2161 accatcggtg tggccttaaa aggtggtttg ccttgggctt ccgttttgcc ttatatctta
     2221 gcccagttcg caggggccat gctgggtcag attttggttt ggttgcaatt caaacctcac
     2281 tatgaggcag aagaaaatgc aggcaatatc ctggcaacct tcagtactgg accagccatc
     2341 aaggatactg tatcaaactt gattagcgaa atccttggaa cctttgtttt ggtgttgaca
     2401 atctttgctt tgggtcttta cgattttcag gcaggtatcg gaacctttgc agtgggaact
     2461 ttgattgtcg gtatcggtct atcactaggt gggacaacag gttatgcctt gaacccagct
     2521 cgtgaccttg gacctcgtat catgcacagc atcttgccaa ttccaaacaa gggagacgga
     2581 gactggtctt acgcttggat tcctgttgta ggccctgtta tcggagcagc cttggcagtg
     2641 cttgtattct cacttttcta gtt
//
LOCUS       DAVBOM010000097         2658 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBOM010000097 DAVBOM010000000
VERSION     DAVBOM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.098"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            448..2553
                     /locus_tag="VQ878_002081"
     CDS             448..2553
                     /locus_tag="VQ878_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3096358.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          850 a          480 c          614 g          714 t
ORIGIN      
        1 tcctgatcga tttgtcctgt tcttatttca ttttaatata tagttttgag atggttgata
       61 gaactgacga agtcagctca aaacatggtt ttgaggttgt agataaggag aagctgatgt
      121 ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt cagttaaagc caaaactctt
      181 gaccttttct gaccaatgta gtatattatg aacgtaaggt aaatgaaagc cttactagaa
      241 cacttattta aagtaaaata gaaagaggtg ggtctatgtt tcatctagaa atcttcagaa
      301 gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga aatagtacgt agggtagcgg
      361 tttaactagt ctaaattttt taaaacaatg gtcaaagata gtcaatatca gtaatcataa
      421 ctaagtaaac aaaaagaggt aaagaatatg aataacaact ttaataattt taataacatg
      481 gatgatttat ttaaccaatt gatgggtggt atgcgaggat atagttctga aaatcgccgt
      541 tacttaatta atggacgcga agtcacatct gaggaatttg ctcactatcg tgcgactggt
      601 caattaccag gaaatgcaga aactgatgtg caaatgccac aacaggcatc aggtatgaaa
      661 caagacggtg tccttgcaaa actaggtcga aacttgacag cagaagcgcg tgagggtaag
      721 ttggatcctg ttatcggacg aaacaaggaa attcaagaaa catctgaaat cctctcacgc
      781 cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg ttggtaagac agcagttgtc
      841 gaaggtctag cgcaagccat tgtgaacgga gatgttcctg ctgctatcaa gaacaaggaa
      901 attatttcta ttgatatctc aggtcttgag gctggtactc aataccgtgg tagctttgaa
      961 gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag ggaatattat cctcttcttt
     1021 gatgaaattc accaaattct tggtgctggt agcactggtg gagacagtgg ttctaaagga
     1081 cttgcggata ttctcaagcc agctctctct cgtggagaat tgacagtgat tggggcaaca
     1141 actcaagacg aataccgtaa caccatcttg aagaatgctg ctcttgctcg tcgtttcaac
     1201 gaagtgaagg tcaatgctcc ttcagcagag aatactttta aaattcttca aggcattcgt
     1261 gacctctatc aacaacatca caatgtcatc ttgccagacg aagtcttgaa agcagcggtg
     1321 gattattctg ttcaatacat tcctcaacgt agcttgccag ataaggctat tgaccttgtc
     1381 gatgtaacag ctgctcactt ggcggctcaa catccagtaa cagatgtgca tgctgttgaa
     1441 cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag ttgaagcaga agattttgaa
     1501 gcagctctaa actataaaac gcgcattgca gaattggaaa ggaaaatcga aaaccacaca
     1561 gaagatatga aagtgactgc aagtgtcaac gatgtggctg aatctgtgga acgaatgaca
     1621 ggtatcccag tatcgcaaat gggagcttca gatatcgaac gtttgaaaga tatggctcat
     1681 cgcttgcaag acaaggtgat tggtcaagat aaggccgtag aagctgtagc tcgtgctatc
     1741 cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa tcggcagctt cctctttgta
     1801 gggtctactg gggttggtaa gacggagctt gctaagcaat tggcactcga tatgtttgga
     1861 acccaggatg cgattatccg tttggatatg tctgaataca gtgaccgcac agctgtttct
     1921 aagctaattg gtacaacagc aggctatgtg ggttatgatg acaatagcaa taccttaaca
     1981 gaacgtgttc gtcgcaatcc atactctatc attctcttgg atgaaattga aaaggctgac
     2041 cctcaagtta ttacccttct cctccaagtt ctagatgatg gtcgtttgac agatggtcaa
     2101 ggaaatacag taaacttcaa gaacactgtc attattgcga cctcaaatgc tggatttggc
     2161 tatgaagcca acttgacaga agatgcggat aaaccagaat tgatggaccg tttgaaaccc
     2221 ttcttccgtc cagaattcct caaccgcttt aatgcagtca tcgagttctc acacttgact
     2281 aaggaagacc tttctaagat tgtagatttg atgttggctg aagttaacca aaccttggct
     2341 aagaaagaca ttgacttggt agtcagtcaa gcggctaaag attatatcac agaagaaggt
     2401 tacgacgaag tcatgggggt tcgtcctctc cgtcgagtgg ttgaacaaga aattcgtgat
     2461 aaggtgacag acttccactt ggatcattta gatgctaaac atctggaagc agatatggaa
     2521 gatggcgttt tggttattcg tgagaaagcc taagacagaa ttttgaggat aaaaaagaag
     2581 gagccagctg aaaaaaactg gttcctttct aggtacgacg ggcatgtcgt gtagtaggtt
     2641 gaaactagaa tagtacac
//
LOCUS       DAVBOM010000098         2634 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBOM010000098 DAVBOM010000000
VERSION     DAVBOM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.099"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            213..527
                     /locus_tag="VQ878_002082"
     CDS             213..527
                     /locus_tag="VQ878_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096359.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            537..743
                     /locus_tag="VQ878_002083"
     CDS             537..743
                     /locus_tag="VQ878_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3096360.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            743..940
                     /locus_tag="VQ878_002084"
     CDS             743..940
                     /locus_tag="VQ878_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096361.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            943..1677
                     /locus_tag="VQ878_002085"
     CDS             943..1677
                     /locus_tag="VQ878_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET3096362.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1689..2330
                     /locus_tag="VQ878_002086"
     CDS             1689..2330
                     /locus_tag="VQ878_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3096363.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2348..2578
                     /locus_tag="VQ878_002087"
     CDS             2348..2578
                     /locus_tag="VQ878_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096364.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          778 a          432 c          538 g          886 t
ORIGIN      
        1 aaccatgcct acggcaaggt gaagctgacg tggtttgaag agattttaga agagtattaa
       61 tgatagataa agtggtcagg aacttactcc tgaccttttt cttttgcaaa atgacaaaaa
      121 tcataaactt tttgacaact ataattgtca aaaagaaaaa gatatgttac aatgaattca
      181 agttaagaaa taggaagcag aaaggagtta taatgtgggt actaggattt atactattta
      241 tgattttctt ttattctaat aattctaaaa aaatcaagaa actagagaat aaaatcaaaa
      301 aacttgagcg aaaagagaaa ggaaacgcag aaatgtcgag attattacaa gaaatgattg
      361 gaaaggaacc aattataacg ggagtgtata ttgggccaga taactgggaa gttgtggatg
      421 ttgatgagga atgggtcaaa ctacgtagtg ttgataatac gggaaaagaa aaattcaagt
      481 tgcaacgtat tgaagatatc caaaccgttg aatttgacgg agagtaggtg tgtaacgtgc
      541 aactaaaaaa tcgtctaaaa gagcttcgag ctcgcgatgg tctcaatcaa accgacctag
      601 ccaaactggc aggggtttcc agacagacca ttagcctact agaacgggat gagtacaccc
      661 catccattat cattgccctg aaaatatctc aaattttcaa cgaaacagtc gaatcggtat
      721 ttcgtttgga ggaggacgag tgatgaacaa gtataaagtg atttattatg tagtggtcat
      781 agctttatta gtcagcgtat ttctactgat tgggatggac ctaagctggt ttaatcccta
      841 tcaaagcgac caatttgttt gggtctactt tgctctcatc ccagtaactg aatggattga
      901 aaagaaatcc aaaaatctag caagtgaaaa aggagaatga atatgaaaaa gaaacgtaga
      961 ttgttatttt tgatgtctat tgtcttgggg gggttcttgg gcatgtttgt agggatgttt
     1021 aaggcacgtg tcgaatccca cgaaattatt ttagatgtaa aagccttgat gccatggata
     1081 tcagctattt gtttactgat aggtttcatt agtatgtttt tgactttcaa tttcttaaag
     1141 aaaagcagaa aatttcattc cttgtatcaa gaggaaatgg atgacgatct gaatgaaacc
     1201 tattatgtgc aaatgtatcg gaatcttgag tttggaacca ttgcttttaa tattacaggt
     1261 gtagcgattc cattggctat ttttatttca ttaagtgagg tgattatatt gcatacaaac
     1321 cctcaaacat ttttcctttc tttcttactc tttgtggtat tcttagtcgc tcaaaaatct
     1381 ctttttaaaa ccattgcgat tgttcgtcag tttgatttgg aatttttcgc tacaccaaag
     1441 gatgtcttga actatataaa ttcttatgat gaaggggagc gtcaggctaa tttggaacag
     1501 agttttcgaa ttttattcca attacaccaa tatgtcttac cagccttata tatttttctt
     1561 attatcattt ctttcttgac aggagagatt cagttactag ctttcttgct tgtaggagcc
     1621 atccatgttt atatcaatgt gatgcagtta cctatggtaa aacgttattt caaataaagg
     1681 agttatctat gaaattactt aaaaaccttg gctggattct tctagccctt ctatcctttt
     1741 tatttatcta tggctttatt caggggctcg cgactgcgtc gcttgcttta ggcgcttcac
     1801 cctatgctgt tactctactc tatgtggcct tggctggagt atatgtgtac ggcatttaca
     1861 aatggtatca gaaggctcct gttcatattg agaagagcgg ctttaatcga tttatttggc
     1921 ttcctgtctt ggtttggttc ttatctctgg tcgttcaatt cttcttgcca gatgatcctt
     1981 cagtaaatca acaaatagcg acagacttga ccttgtctca accacttttc tcattctttg
     2041 ctgtggttat ttttgctcct ttgacggaag agattgtttt tagagggatg ttagcacgct
     2101 atctctttcc taagcaggac aatagtaaac gaaccctgat ttttcttctg gtatctagtc
     2161 ttctatttgc cttgattcat tttccaggtg atgtgcaaca attttttgtc tattttagcc
     2221 ttggttttag tttgggtttg gcttacatta gcagaaaagg tctggtctac agtatttctc
     2281 ttcacgcttt gaataattta gtcggctttt tgatgattct catgctataa tagagtcagg
     2341 aggtcacatg aaacgagtaa ttttagtagc agtgattcag gcagtcgttc tatttttcat
     2401 cattggagcg ctagcttatg ccttcaaagg cgatttcttc tataactatc tagcagttgt
     2461 ctttgctcct attgcaggtg tactgcgttt tgggacggct tacataacgg aaattgtctt
     2521 gcctcgaaag gcagccgaaa tcgctgaaaa gcgtaaagca ggcaaaaatt caaaataaaa
     2581 gagtccggtg aagttcatcg gatttttgta ttatactcaa tgaaaatcaa agag
//
LOCUS       DAVBOM010000099         2535 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBOM010000099 DAVBOM010000000
VERSION     DAVBOM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.100"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VQ878_002088"
     CDS             <1..559
                     /locus_tag="VQ878_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3096365.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VQ878_002089"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VQ878_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET3096366.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2029
                     /locus_tag="VQ878_002090"
     CDS             1424..2029
                     /locus_tag="VQ878_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3096367.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1977..>2535)
                     /locus_tag="VQ878_002091"
     CDS             complement(1977..>2535)
                     /locus_tag="VQ878_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3096368.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          864 a          363 c          439 g          869 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagggat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caatgaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgaac aagtttattt
     1681 aaaacataat cagctaataa cacctgtatc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtctt ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacactg agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tggaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 cctttgatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttattagca taggggaata tcgatataat ggcttcatta
     2221 tgagtggcag gaatatccaa tatggcaact tttccaatag ataatttaaa actcattaat
     2281 aaagttcctt taggtgaaat gtctattttc tttgatttta atgctaattt agaaatagat
     2341 tctctcgtat tagttacata accagatata ggcatatctg atatagatac ccaaggtatt
     2401 tcagttcccc aaaaagtagc ttcactgcgt ggaggagttt ttcctattct gaagttaact
     2461 aggctagcaa atttaatata tctccatgct tctgggattt catatatagg ataagaggtt
     2521 gtttcgtctt tgttc
//
LOCUS       DAVBOM010000100         2487 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBOM010000100 DAVBOM010000000
VERSION     DAVBOM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.101"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(173..838)
                     /locus_tag="VQ878_002092"
     CDS             complement(173..838)
                     /locus_tag="VQ878_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET3096369.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VQ878_002093"
     CDS             complement(852..2231)
                     /locus_tag="VQ878_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3096370.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRFIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          815 a          566 c          465 g          641 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 ataaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaagcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagttcgaaa tgacttagat aggataaggc
     2281 aaaatctact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt cacaggt
//
LOCUS       DAVBOM010000101         2364 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBOM010000101 DAVBOM010000000
VERSION     DAVBOM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.102"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..1523
                     /gene="phtA"
                     /locus_tag="VQ878_002094"
     CDS             <1..1523
                     /gene="phtA"
                     /locus_tag="VQ878_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3096371.1"
                     /translation="FDPAQITSRTARGVAVPHGDHYHFIPYSHMSELEERIARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEK
                     GISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEA
                     HKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQI
                     EYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEK
                     VAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEV
                     KNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGW
                     GNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAK
                     VTDSSLKANATETLAGLRNNLILQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1681..>2364
                     /locus_tag="VQ878_002095"
     CDS             1681..>2364
                     /locus_tag="VQ878_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3096372.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT          831 a          430 c          476 g          627 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg ccacacggag
       61 atcattacca cttcatccct tactctcaca tgtctgaatt ggaagaacga atcgctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat cttaaaatag
      241 actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga tatgtattcg
      301 aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa actgttaaaa
      361 atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact gctaaaaaag
      421 aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg ttaactgagg
      481 ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc ttagacaaat
      541 tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat gatttattgg
      601 cattcctagc accaattacc catccagagc gacttggcaa gccaaattct caaattgagt
      661 atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg tcagatggtt
      721 acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta acgcctcata
      781 tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa gttgcagctc
      841 aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat gttaaagcaa
      901 atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa aaacgaattc
      961 cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac ggtaatttga
     1021 ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat gatcacacat
     1081 acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag tactacgtag
     1141 aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt gagcatgtgt
     1201 taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat gaagagccag
     1261 tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa gtagaagccc
     1321 aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg aaagccaatg
     1381 caacagaaac tctagctggt ttacgaaata atttgattct tcaaattatg gataacaata
     1441 gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat ccttcatctg
     1501 taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg ctttcatttt
     1561 tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa ctattaacta
     1621 gttaattaac cggtttatta ctttatagtg aatcaaatat acttaagaaa agaggaaaga
     1681 atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt aagtgtctgt
     1741 gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg tgtttcctat
     1801 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
     1861 cgtgaaggaa tcaatgccga acaaatcgtc atcaaaataa cagaccaagg ctatgtcact
     1921 tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc tatcatcagt
     1981 gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat tatcagtgaa
     2041 atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct taaggatgca
     2101 gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agagcatagt
     2161 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcacag
     2221 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaagatact
     2281 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     2341 tcagctagcg agttagctgc tgca
//
LOCUS       DAVBOM010000102         2268 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBOM010000102 DAVBOM010000000
VERSION     DAVBOM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2268
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.103"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            70..608
                     /locus_tag="VQ878_002096"
                     /pseudo
     CDS             70..608
                     /locus_tag="VQ878_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            675..1085
                     /locus_tag="VQ878_002097"
     CDS             675..1085
                     /locus_tag="VQ878_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET3096373.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1201..>2268
                     /gene="pavB"
                     /locus_tag="VQ878_002098"
     CDS             1201..>2268
                     /gene="pavB"
                     /locus_tag="VQ878_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET3096374.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKAS"
BASE COUNT          687 a          441 c          508 g          632 t
ORIGIN      
        1 gacgttgacg cggtttgaag agattttcga agagtataag aaaaaatcag tcccctaaag
       61 gagcagatta tgaagttatt gtctatcgcc atttctagct ataatgcagc agcctatctt
      121 cattactgtg tggagtcgct agtgattggt ggtgagcaag ttgggatttt gattatcaat
      181 gacgggtctc aggatcagac tcagaaatcg ctgagtgttt agctagcaag tatcctaata
      241 tcgttagagc catctatcag gaaaataaag gccatggcgg tgcggtcaat cgtggcttgg
      301 cagaggcttc tgggcgctat tttaaagtag ttgacagtga tgactgggtg gatcctcgtg
      361 cctacttgaa aattcttgaa accttgcagg aacttgagag caaaggtcaa gaggtggatg
      421 tctttgtgac caattttgtc tatgaaaagg aagggcagtc tcgtaagaag agtatgagtt
      481 acgagtcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga aatttctcca
      541 aaggccagta taccatgatg cactcgctga tttatcggac agatttgttg cgtgctagcc
      601 agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt acgccccttc
      661 agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg attgggcgtg
      721 aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa ctcaaggtca
      781 atcgactctt ggtagaccaa cttgatttgt cccaagtgag tcatcccaaa atgcgagaat
      841 atctgctgaa tcatattgaa atcacgacgg tgatttccag taccctgctc aaccgatctg
      901 gaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag cagaaaaatc
      961 cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa cattctgtct
     1021 tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt tatggattta
     1081 attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt cttagtcctt
     1141 tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa ggagaatcct
     1201 atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct cagtgtcggt
     1261 gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc aagttctgta
     1321 cgtgccgatg tggtcaatcc gaccccaggt caagtcttac ctgaagagac atcgggaacg
     1381 aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc gaaacctgag
     1441 ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga agtgagcgag
     1501 gaaacaaact cttctagtct ggatacactt tttgaaaaag atgaagaagc tcaaaaaaat
     1561 ccagagctaa cagatgtctt aaaagaaact gtagatacag ctgatgtgga tgggacacaa
     1621 gcaagtccag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga aaatacaaaa
     1681 gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg tcctttcact
     1741 gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat gttaactcgt
     1801 ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc taaaaatcct
     1861 gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt agacttaaat
     1921 ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc taatggtact
     1981 caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc tgacttgact
     2041 aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc taaagaaaca
     2101 gttcaaaaag ccgttgcaga taacgttaag gacagtatcg atgttccagc agcctaccta
     2161 gaaaaggcca agggtgaagg tccattcaca gcaggtgtca accatgtgat tccatatgaa
     2221 ctcttcgcag gtgatggtat gttgactcgt ctcttgctca aggcatct
//
LOCUS       DAVBOM010000103         1977 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBOM010000103 DAVBOM010000000
VERSION     DAVBOM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1977
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.104"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..917)
                     /locus_tag="VQ878_002099"
     CDS             complement(<1..917)
                     /locus_tag="VQ878_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3096375.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCL"
     gene            complement(1362..1760)
                     /locus_tag="VQ878_002100"
     CDS             complement(1362..1760)
                     /locus_tag="VQ878_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3096376.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          547 a          401 c          347 g          682 t
ORIGIN      
        1 tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttctttggga
       61 gtcattttct tggttccctt aggtaaccat ctacgaatga acctgttgtg attctcatta
      121 gttccccttt cccaagaggc ataggggtgc gcataataaa tgtgctcctc agaaaataca
      181 tcagacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat cttgtgttgt
      241 tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg aatcaatcgg
      301 atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt tttcgctctc
      361 gtaagtagaa ccgtatcaat ctcataatgc ccattctcca agcgaagatt gatagcttca
      421 ggccgctgtg cgatggattg accagcaggt ttaaagttgg tgctggcctg tttcttaagc
      481 gcttttcctt ttctagggta aggcaaatcc tgcttgctta accccaattt tccatgatga
      541 atccaatagt aaatggttga aattcccacg ttaacccctt tagccatcac catcatttca
      601 ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt ggtcaagctt
      661 gatttcttga ccgagcgctt gcgattgttt tcataagact gttgagcgta gtcggcagaa
      721 taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg cttgatttca
      781 gtgtggatag tttgaggagc ttttccaagt agagaggcaa cttctctatt tgattttcct
      841 tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt accttttgta
      901 gtataattgt cttgcatttc tgtgcctttc ttgtgtttgt ggttgaacaa caagtataac
      961 acagaggtgt tttcttatgc ctacaagagc tttcattatt tccattttct tttggatttc
     1021 actctattct gaaaaacttg tgtatattta ctgaagctag caagtcttac ctgtaaattt
     1081 aatgaaagca acacaaaatc cgagagggga atctcggatt aatagataga gagtttttag
     1141 tttaaataaa ttgtttaaaa tatcaacaac atcacttctt ttcttaacct gataagtctt
     1201 gattcctaat tttggggcta cgattatatt gtcctcaata tcgtctagaa agacacaatt
     1261 tctaggttat aactggtatt tatcgatagt tactcatata catcagtcca cctccatact
     1321 tatgtgcgag cctctctttg tattatacct ccatactcac cttacagatt cttttggtaa
     1381 taatatcttt gcctaatgta gagatagtct tgcaaagaaa aaacttcctt gtagccatgt
     1441 ttctgataaa agtccggtgc ctggaactgg taagtattga caaaggcaaa acaacaattt
     1501 cgattcttag cttcactttc tgcctgttgc aatagttttg aaccgattcc ttgccctcgc
     1561 agttcctctt ttacaaacaa atactcgatt tctagccaat ttccaaaagt ctctgctatc
     1621 aaacctgcca ggagattgcc cttttcatct tcgacataaa gattaagtgg ctcactttca
     1681 gcctcttctc tttttgaacg gttataaaca cgaatcagat tccctatttc ttgcgattta
     1741 tgtgattcct tattttccaa tctaatgaaa tgaaataaaa catgcgcaaa tcgattaagg
     1801 aatttaatct aatttctaac aatgtcttag aaatcaaagt gtactatttt aacttcaatg
     1861 cactatacat ctaatactca atgaaaatca aagagcaaac taggaaacta gccgcaggtt
     1921 gctcaaaaca ctgttttgag gttgtagata gaactgacga agtcagctca aaacatg
//
LOCUS       DAVBOM010000104         1860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBOM010000104 DAVBOM010000000
VERSION     DAVBOM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.105"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VQ878_002101"
     CDS             complement(3..968)
                     /locus_tag="VQ878_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3096377.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VQ878_002102"
     CDS             complement(1086..1499)
                     /locus_tag="VQ878_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET3096378.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VQ878_002103"
     CDS             complement(1496..1732)
                     /locus_tag="VQ878_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET3096379.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          363 c          276 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVBOM010000105         1817 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBOM010000105 DAVBOM010000000
VERSION     DAVBOM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.106"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(400..780)
                     /locus_tag="VQ878_002104"
                     /pseudo
     CDS             complement(400..780)
                     /locus_tag="VQ878_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(1202..>1817)
                     /locus_tag="VQ878_002105"
     CDS             complement(1202..>1817)
                     /locus_tag="VQ878_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET3096380.1"
                     /translation="NLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYSLED
                     LLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEE
                     TPREEKPQSEKPESPKPTEEPEEESPEESPEESEEPQVETEKVKEKLREAEDLLGKIQ
                     NPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          539 a          364 c          273 g          641 t
ORIGIN      
        1 caattaacta atttaatcac ttaaaaaaat tcgaacactt tctatacaac tgacagctca
       61 aatctttcag aatagaacaa tactaactat cgagcacccc gtattcataa atatatgtgt
      121 aattctagac ctagaattcc tataaactaa atgctttcat actcttccaa gtaattgatt
      181 gccttaaatt ttaatttttg aaggtttcta aagctagaat agccccatca caatcagttt
      241 tgattgattc acaatttaga aacactatag tttcactcct gttaaaataa aaaggaactg
      301 cataaagcaa tccctttctg attttgaaat catttactta acattttata gttgagataa
      361 tcaatagctt acctataaaa agagttatag taaaattcct tatttattga tttcaagctc
      421 cgctaactgt gtttgaataa ctgacagttc tgcaccagcc tgaagaagag cagctgcatt
      481 ataggcacct tctacaattg gaaccctgtt gatgatgata cttttatcac tgaaatcagt
      541 caccattttt aagttcattt tagcaaaacc taggtcaaaa aaggcaagta aagtatctgc
      601 tgtattttcg gaaacaaccc tatctactta atcaaaactc gttccaattc ctccgccctc
      661 ggttcctcct acataagtaa tcggaacatc tttagctact ttactaatca gttcaacaac
      721 accttctaca atgtatttgg aatgtgaaac gataacaaga ccaataccaa tactttccat
      781 caaaccaccc cagtttctaa aatagcagta aagagtaatc ctgatgagaa tgatccagga
      841 tcaatatgtc caagaaacca catgctccta agacaagagc taacagactg gccatcaata
      901 atagtattgt tctttttttc atcattactc cttaactagt gtttaactga tcaattagcc
      961 agtaaatagt ttatctttat ttacactatc tgttaagata tagtaaaatg aaataagaac
     1021 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     1081 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     1141 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     1201 tttacttact ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt
     1261 tgtcctgggt gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg
     1321 acttgataat tggattctgg atttttccaa gtaaatcttc agcctctctc agtttttctt
     1381 taaccttttc agtctcgacc tgaggttctt ctgattcctc tggtgattct tctggtgatt
     1441 cttcttctgg ttcctctgtt ggttttggag actctggttt ctcgctttgc ggtttctctt
     1501 ctcgaggggt ttcttcctca ggtttttctg tctgaggttt ctcctcgttt ggtttttccg
     1561 tttgattggt atcagcttga ccatttttgt ttctttgaac atggtcgcta gcgttaccaa
     1621 aaccattatc tgaatgcgga cgttcgtttg gatgttcgac atagtacttg acagtcgcca
     1681 aaagatcctc aagactatac cccttaggtg cctcataaag gccttcgtca aaccactcaa
     1741 atttgatgtt atggtaatgg tcataatgag gtatgattaa actaccgttt ttgacttcta
     1801 cagtatattg aagattg
//
LOCUS       DAVBOM010000106         1801 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBOM010000106 DAVBOM010000000
VERSION     DAVBOM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.107"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(101..642)
                     /locus_tag="VQ878_002106"
                     /pseudo
     CDS             complement(101..642)
                     /locus_tag="VQ878_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(718..1494)
                     /locus_tag="VQ878_002107"
                     /pseudo
     CDS             complement(718..1494)
                     /locus_tag="VQ878_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1418..1612)
                     /locus_tag="VQ878_002108"
     CDS             complement(1418..1612)
                     /locus_tag="VQ878_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3096381.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
BASE COUNT          509 a          380 c          331 g          581 t
ORIGIN      
        1 tggattgaaa taagatatga acaaatcgat taggaaagga aaattgattt atagaaatat
       61 tttagcagtc gatgcgtact gttatagatt caacgcacta taattgatga cgtttagctg
      121 tttccaacaa actcataata atagctcttg ctttagctcc ttcaaaactt tgagaaaata
      181 accaccctcg cttttttaaa ctgagctcag gctaaaagag tccactggac tcttttactc
      241 cgtcccataa ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt
      301 ccgtctttta aaatggtctt aaaggtttct ttatacttga ggctgtattc aattgccctt
      361 cctagttttg aacctgctaa aactgactga cggcggcacc aagcaaagaa gtcttccatt
      421 aggggctgga cgtttctgta gtcgttcatc agctggcaaa gcctcccagt ctctttccaa
      481 ggcaaataac tggtcacgat aggctaaacc tttagctcct aaggatgatt tatctgcttg
      541 cttgggggtc gcttcaaaaa atttccttct cacatgcgcc caacatccaa caagttcagc
      601 ttcttccagt tgacgataag cttctagcgg ttcgcagttt accaagctta gcgtcgcctt
      661 gctcctaaac cttagactgc tatcgcatag gcagaactag aggactaaag ttctaagtta
      721 ctgccgcaac atatcacaat gcatatagcc agaataattt cctaggaatt cttgcactac
      781 cgaaccactc cgacgctgat catggtggta cagcgtaatc ccttgtttct cagctttccc
      841 agacaaaaaa gtccaatagt aagtcagctg actatcactt tctaagaccc gataagaggt
      901 ttcatctgca tgaagaagag cttgttctaa caacttttct cgtaaaaggt tataaaggga
      961 ctctaaatag tattgactcg ccttgatatg ccaattagca atttccttac gtgtgattgg
     1021 taaacccatc ttagcccaat cttcttctta gcgataattg ggtaccttca gaataaactt
     1081 ctgatggatg gtgtgagcga taatagaagc tgagccaagg ctatgcgcca aaggggcttt
     1141 aggaatagga gctttcacga ttttatcact tggattattc ttactgcatg tttggcattt
     1201 gtaagcgtgt tggatatgat tcactctttt taattgcgca agaataaaga ccaattcttg
     1261 tcgttgaagg ctcgctccaa tctcttttag ctctccctga cagtcagggc aaatgcagtt
     1321 ctctaagcga tgatgaactt cttctgaatc aaattgggca agaatagctt gacgtttccc
     1381 tttagctttc ttacgtttat aggtgatttc ttctctttca actgggtaag tcagagtctt
     1441 cttccatatt ttgttcctct tcaaaaagac tgagttgtcc agatgggcaa acacttttct
     1501 cagaggattt tccatagagc ttttgcgtta gataagccac ttgttcacga agaagggcaa
     1561 gttcattggt gagactatca attgtagcac tctgttgttg aatgattttc aatcttctcc
     1621 catagacttt cctccttatt tcctaacttt attatatagt gtattgaatc tataacagta
     1681 caccttgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcat
     1741 atcttatttc aattcactat actaaaaaga aagtcctcat ttcaatagaa atcacgactt
     1801 t
//
LOCUS       DAVBOM010000107         1646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBOM010000107 DAVBOM010000000
VERSION     DAVBOM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.108"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(242..1006)
                     /locus_tag="VQ878_002109"
     CDS             complement(242..1006)
                     /locus_tag="VQ878_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET3096382.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLNQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1228..1524
                     /locus_tag="VQ878_002110"
     CDS             1228..1524
                     /locus_tag="VQ878_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3096383.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          522 a          404 c          316 g          404 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaagttt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtaac ctcgtttaaa
      181 catatttttg aaaagtatga gctaggcatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggttcaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gtcttcttcc ttgcgataag ccaccttttc agccgtttct cggtaaaaac
      481 catctgtgga ccaggtcatg acttcttcat aaggaatccc tctatcatcc aaaactcgct
      541 caatggcagc aatagcctct ggctgcattt ccatataacg agaaggtgcc acatagtggt
      601 aactggctcc ttcatctcgc agagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagctgaac cgacaggagc ctgaaccaga caaatctcct
      781 cgtccttgta gttcacgaca taaactggat aggtcttggt ggcagaaaca aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa ataggaatcg catgtttctg aatcatagcc cacctcctct
     1021 aattttgtac tattgtatca aaatctgaca aagtgtcaag gaggaagctg atgaactgag
     1081 gagaaaaaca agcctacatc gtcagctgcc acagtggttt gcgcagctat atcgcagagc
     1141 ctatcctcaa gcaagcagga tttaccgtcc aaaaccttga cggcgcttat tcactataca
     1201 aaatgactaa cccagaagga gtagaatatg gaaactagta tcagcatggc tgacttttat
     1261 ggaaaatatc aaaatgaaaa tctagaactt atcgatgtcc gtgaagcaca tgaattccaa
     1321 gcaggacatg caccagatgc caaaaatctt ccattaagta ccttagagca aggctacaaa
     1381 gaactcaaac ctgaccatga atactatgtt atttgtcaag gaggagtccg ctctgcatct
     1441 acctgccaat ttctcagctc ccaaggcctc accgttacca acgtagaagg tggtatgaat
     1501 gcttggcccg gtcaagtaga ataatcaaga ggagctgggc aaaaactcaa tttcaggaga
     1561 agatgaagta atactcaatg aaaattaaag tgcaaactag gaagttagcc gcaggctgct
     1621 caaaacactg ttttaaggtt gtggat
//
LOCUS       DAVBOM010000108         1409 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBOM010000108 DAVBOM010000000
VERSION     DAVBOM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.109"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            283..1293
                     /gene="ccpA"
                     /locus_tag="VQ878_002111"
     CDS             283..1293
                     /gene="ccpA"
                     /locus_tag="VQ878_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET3096384.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT          440 a          232 c          318 g          419 t
ORIGIN      
        1 tcctgttctt atttcatttt actataactt taggagggct tagtttcctc ctttttgttt
       61 agtctaaggt ggtagcaagg agctaaacct aggttttcta tgaaattttt tcaatcaatc
      121 ttcaaaaaac acttgaaagt gtttacaatt agtgatagaa tggaataagt agaaatatga
      181 aaacgaaatt ttcacatctt cacttttgta agtagatata gagcttcaat cagcacctct
      241 acttgtaaaa gaatatgtga gatagaaagg acaggaaaag gaatgaatgc agatgataca
      301 gtaaccattt atgatgtcgc tcgtgaagca ggtgtttcca tggcgacggt cagccgtgtg
      361 gtcaatggca ataaaaatgt aaaagagaat acccgtaaaa aagtgctaga ggtaattgat
      421 cgtttggatt atcgtccaaa tgcagttgcg cgtggtcttg caagtaaaaa gacaaccact
      481 gtcggtgtcg tgattccaaa tattaccaat ggttattttt cgagtttggc taaggggatt
      541 gatgatattg cagaaatgta caagtacaat attgtcctag ctaatagcga tgaagataac
      601 gagaaagaag tttctgttgt caataccctc ttttcaaagc aggtagatgg cattatctat
      661 atgggttatc acttgacaga taaaattcgc tcagaatttt cgcgctcacg tactccgatt
      721 gttctcgcag gaactgtcga tgttgagcac cagttgccaa gtgtcaatat tgactataag
      781 caagcaacaa ttgatgcagt gagttacctt gctaaagaaa atgagcgtat tgctttcgtt
      841 agcggtccgc tagtggatga catcaatggt aaggttcgtt tagttggcta caaggaaacc
      901 ttgaaaaaag caggaatcac ttatagtgag ggtttggtat ttgaatctaa atatagctat
      961 gatgatggtt acgccttagc agagcgtttg atttcatcaa atgcaactgc agcagttgtg
     1021 acaggtgatg agttggcagc aggagtcttg aacggtttgg ctgataaagg tgtttctgtg
     1081 ccagaagatt ttgaaattat tactagtgat gattcacaaa tctcacgctt tacccgtcca
     1141 aacttgacaa cgattgccca acctctttat gaccttggtg ctattagtat gcgtatgttg
     1201 accaagatta tgcataagga agagttggaa gaacgtgaag ttctcttacc tcatggtttg
     1261 acagaacgta gctcaacacg aaaacgtaaa tagaaaaaat cagggaatcg agaagatttc
     1321 ctgattttgt gctcttaaac aagagatgtt gacttaatga ataccataga gcggactagg
     1381 cggctggtta aaggctgcgc aacacactg
//
LOCUS       DAVBOM010000109         1220 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBOM010000109 DAVBOM010000000
VERSION     DAVBOM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.110"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(1..424)
                     /locus_tag="VQ878_002112"
                     /pseudo
     CDS             complement(1..424)
                     /locus_tag="VQ878_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840321.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(736..1047)
                     /locus_tag="VQ878_002113"
     CDS             complement(736..1047)
                     /locus_tag="VQ878_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096385.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(1062..>1220)
                     /locus_tag="VQ878_002114"
     CDS             complement(1062..>1220)
                     /locus_tag="VQ878_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3096386.1"
                     /translation="AKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINFYKED
                     GTSVTVRA"
BASE COUNT          363 a          250 c          211 g          396 t
ORIGIN      
        1 cgttgacgaa tggttgctgt ttgtgtcgca tcatcataag aaatcacttc agcgacaaac
       61 ttgtactcag gaattttacg acgagcacca aacaactgct cattttcaga tggtatacca
      121 tagtaaaatc ctgtagccag ttcacgttgg gcaaccttcc acatctcgtc caccaagtct
      181 tgtttgatag cttcaaactt ttcaggactt tcaagatagg catccacagc cgccttgtag
      241 cagttggtta ctgttgatac gtagtgaata gactccactc catacgtcct tcgattttta
      301 gattgtccac accattttca atcatatctg gaatgtggtc aatcatagac atgtcaacgg
      361 ctgacattga aaattcttct ggaatctcac cctgcaaact cttacgttct ttcccaaatg
      421 gcatatcgta aaggtcgtat ttccaacggc atgactgaga acatccacca cggttggcat
      481 cacgcatact ctagacggat tgttttgaca attctaatct tttagacttt gcataataac
      541 tgttaaacag tcgaaaatta ccccagtttt aacaagtagt caaaatacca gataaaggaa
      601 aaaagtcttt aaaatcttaa aaacgcatag tatcaggtat tgaacaatct tgatattatg
      661 cgttttattg tgggaagatt tacttcattt tctcttgaaa ttgagttttc tcctacttca
      721 aaactagatg atttgctatt taaaatagcg ttccttatga ttttggcaac ctggattaaa
      781 gcgagaaaaa caaaaggggc aacttaaact ttctttatat tgcttatatg ttagtagttt
      841 tagacaaaca ccacataaaa taggcttatc ctgtatcaaa gataagggat acggctcaaa
      901 agggtgattt tctaatgaat catgacaccg ataacaagca taatactttt tacaatcata
      961 gcattgtaaa gcaataatat ccagcttgct atggtaatga atgcatcttg tttgcttatc
     1021 cactaagaaa ccctgtgcct ctatcatttc cttttccttt cttaagctcg aactgtgacg
     1081 ctggttccat cttccttata aaaattgatg agtccttctt ttaatgcacg aaccatgtct
     1141 ccagcttgaa cgggttgtgg gactttaata gtcaatagtt ccattggatt tggagcgcgg
     1201 tcgattttat tgcctttggc
//
LOCUS       DAVBOM010000110         1056 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBOM010000110 DAVBOM010000000
VERSION     DAVBOM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.111"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            97..504
                     /locus_tag="VQ878_002115"
     CDS             97..504
                     /locus_tag="VQ878_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3096387.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            669..968
                     /locus_tag="VQ878_002116"
     CDS             669..968
                     /locus_tag="VQ878_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET3096388.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          371 a          211 c          184 g          290 t
ORIGIN      
        1 tttggttcat ttcactataa taataacgat actagataat gaggaaaatg caatggcaaa
       61 cccaactttc ggagaaaaaa agcgaataca gactatattg ctcgctatgg cgtatatgca
      121 gttatcccta atcctgaaca aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg
      181 ttcctaccat gtggagaaat tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag
      241 ttgattgaag agcttggttt cacagcagaa attggtacct attacggaca agctgacgaa
      301 tatttctatt ctcgtcatcg tgatacctac tactacaatc ctgcctacct ctatgaagca
      361 acttctttca aagaagtaca aaagccacta gaaaacttta atcatattgc ctggttccct
      421 attgacgagg ctatccaaaa ccttaaacgt ggtagccata aatgggccat tgaatcttgg
      481 aaaaaacagc ataagattga ctaatactct tcgaaaataa aatttaaacc acgtcagcgt
      541 cgccttaccg tactcaagta tagcctgcgg ctagcttcct agtttgctct ttgattttca
      601 ttgagtataa atcaagcgac tttattcaaa aagtgctata atagaattag aaaatcggag
      661 gaaatattat gaagcttatc aatacgacaa actcacactc gcaacttgta aaaagtcagc
      721 tagaaagtac cgatgcaacc cttgttgagg tttattctgc agggaataca gatgttattt
      781 ttacccaagc tccgcttcac tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg
      841 agcctgaaat cgaaaccatt caagaatttt tcttgaaacg taaaattgat aagacctctg
      901 ttgatgaagc caatatcaag acactctact cagagaaatt aattggaatt tcaatcccaa
      961 tcaagtaaga aaattgagta aaaactcgat ttgagagaaa gtccaataag tctttccata
     1021 ataaaacgca tagtagcagg tgccgaaatg aactgc
//
LOCUS       DAVBOM010000111         1010 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBOM010000111 DAVBOM010000000
VERSION     DAVBOM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1010
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.112"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(1..606)
                     /locus_tag="VQ878_002117"
                     /pseudo
     CDS             complement(1..606)
                     /locus_tag="VQ878_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            848..>1010
                     /locus_tag="VQ878_002118"
     CDS             848..>1010
                     /locus_tag="VQ878_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3096389.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDR"
BASE COUNT          292 a          193 c          159 g          366 t
ORIGIN      
        1 aatccgacga taaccataat ttcccttgtg ttcgataaaa atggattgaa tttcagcttt
       61 aagctcttgg tccttatctg ttttatctag ctgtttcaag tgatagtagt aggtcgaacg
      121 agctagttta atggctttta gaagaatatc taacgaaaac tcagtcatta attcttgaac
      181 aatttctgtc tttcttcttt ctctttttcc tccttcaatc ggagttctct taactttttt
      241 aggatggcat tttccgctct caggtactct ccctcttgtt ttctcaacaa tagtataccc
      301 gtttttcctg tattgtgcta gccagttaag aagtatcgta cgacttggga gacagtattc
      361 aagagaaact ctatctttag tccagccttc atgtcagact ttattaatca tttcttgttt
      421 taaatcagga gaatagtaac gattttttcc ttttttgacg aactctattc cgtaacgatc
      481 aatcaattta atcatatacc taagattaga attgtttatc ccaaatttat ttgaaagctt
      541 ctctaagcta tatccttgtt ttctaagttc atagatctga actttatcat cataactcaa
      601 tttcataata aaaacacccc aaaagttaga ttttttctgt ctaacttttg gggggcagtt
      661 cattctacac ccactattat gcgtttttat cattttgaaa tctactgcta atcaatgaag
      721 aagcaaagat caaactaggc agctagttac aagttacgta agcgcgtcat aacaaggtat
      781 ctatcctaat tccccaactt ccagtatact agataaaaaa taattatcgg aggaaaggta
      841 ttgtactatg ataattcaac taagtgattt aggtcaagtt caccttgttt gtagcaagat
      901 agatatgagg cagggaatag actcattagc ctatgtagtt aaaacccact ttgaattgga
      961 tcctttctcc ggtcaagtct ttctcttttg tggtggacgt aaagaccgct
//
LOCUS       DAVBOM010000112          996 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBOM010000112 DAVBOM010000000
VERSION     DAVBOM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.113"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..101
                     /locus_tag="VQ878_002119"
     CDS             <1..101
                     /locus_tag="VQ878_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HET3096390.1"
                     /translation="FKRVGIFDGKAVEVTLREPYSRDLLQVVKSIK"
     gene            complement(398..685)
                     /locus_tag="VQ878_002120"
                     /pseudo
     CDS             complement(398..685)
                     /locus_tag="VQ878_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            684..947
                     /locus_tag="VQ878_002121"
                     /pseudo
     CDS             684..947
                     /locus_tag="VQ878_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          367 a          155 c          174 g          300 t
ORIGIN      
        1 aatttaaacg tgttggtatc tttgatggga aagcagtaga agttactctt cgagaacctt
       61 attcgagaga tctactgcag gttgtcaagt caataaagta actgacacca cgagtataat
      121 tattagaaac gtggaatctt attaaatttt ataataaata tattaaatga aaaattatta
      181 gatataaact tatgtaataa aacattgagg aaataataaa aatctatggg taatgttctg
      241 aaagtacttt taggttagga gagaaatata atgatttttg aaaattgatt caaaaaatag
      301 cgaattgtag aaaacgctta acaaatggtg tataatagac ttccagcgaa acaaaatatg
      361 ctacaataaa cctatgaatt ataaagtaac cttatactca tctgtcttca caaagcattc
      421 tagtccatct ccgattaacg atggacttta tcatctcctt ctccagtcct tgtatgacat
      481 cttccaaagt tcgaaaggct ttattcttaa atccacgttt acgaatctct ttccacactt
      541 attcaatggg gttcatttct ggtgtgtatg gaggaataaa tgcaaagcca atattagtcg
      601 gaatctttaa ggcacttgat ttatgccata tagcattgtc cataacgaat aaaagataat
      661 catctggata agcttgtgaa agcttggctg acagtggtta tcaagggctc atgaagatat
      721 atcttcaagc acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gctgaagata
      781 aagcctataa ccatgcgcta tctaaggaga gaagcaaggt tgagaatatt tttgccaaag
      841 taaaaacgtt taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc ttcggattac
      901 gaatgaattt gattgctgat attatcaatc atgaactagg attctagttt tgcaggaagt
      961 ctaataaatg tataagaaaa aggaggaaaa aggatg
//
LOCUS       DAVBOM010000113          837 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBOM010000113 DAVBOM010000000
VERSION     DAVBOM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.114"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            452..>837
                     /locus_tag="VQ878_002122"
     CDS             452..>837
                     /locus_tag="VQ878_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3096391.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKNLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLM"
BASE COUNT          292 a          128 c          155 g          262 t
ORIGIN      
        1 tctagaatgt cttccaaacg tggaaactct cgtaaacaaa gaggttttag aggcctattt
       61 accgtggact aaagttgtac aagaaaagtg caaataagaa atctccagat taggaactat
      121 atatgagttc actaatctgg agatttttca atagacttcg ttattgggcg gttaggatat
      181 gatcactgac ttcgtcagtc ttatctacaa cctcaaaaca gtgttttgag caacctgcgg
      241 ctagcttcct agtttactct ttgattttca ttgagtatta gaacagaaaa aatgcttgga
      301 gtatttgttt gtgtgtttat ttttatataa caaactataa acaaaacaaa aatataaaaa
      361 aagagacaaa aaagaacaga aagtaattga caacggtttc atatagtgtt atacttatgg
      421 cataaagtta atggaaagaa gggaaaaact tatggtatta gattatttct ttgacaaaaa
      481 ccttgtgttt tgcttagaag cggataatca agaacatctc tttgatcagg ttgcaacttt
      541 attggaagaa cgagaaattg taactccaac ttatcgtgaa gccttgatca cgcgtgaaaa
      601 gtcatttcca actggtttag atatggaatt tctaggaaag aacttgccaa atgtagcgat
      661 tcctcacaca gatattgttc ataatctagc tgagaaagtg gtggttgttc gattagaaaa
      721 accagtaact tttcacaata tgatagctcc tgataaggaa gtagaagtat ccctactctt
      781 ctttattatt aacaattcaa gttcaagtca aacaaatatt ctggctcagt tgatgga
//
LOCUS       DAVBOM010000114          765 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBOM010000114 DAVBOM010000000
VERSION     DAVBOM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.115"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ878_002123"
     tRNA            complement(74..147)
                     /locus_tag="VQ878_002123"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ878_002124"
     tRNA            complement(157..242)
                     /locus_tag="VQ878_002124"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ878_002125"
     tRNA            complement(250..321)
                     /locus_tag="VQ878_002125"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ878_002126"
     tRNA            complement(344..416)
                     /locus_tag="VQ878_002126"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ878_002127"
     tRNA            complement(435..516)
                     /locus_tag="VQ878_002127"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ878_002128"
     tRNA            complement(522..594)
                     /locus_tag="VQ878_002128"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ878_002129"
     tRNA            complement(619..691)
                     /locus_tag="VQ878_002129"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..765)
                     /locus_tag="VQ878_002130"
     tRNA            complement(694..765)
                     /locus_tag="VQ878_002130"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          195 a          225 c          168 g          177 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcc
//
LOCUS       DAVBOM010000115          759 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBOM010000115 DAVBOM010000000
VERSION     DAVBOM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.116"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            3..305
                     /locus_tag="VQ878_002131"
     CDS             3..305
                     /locus_tag="VQ878_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3096392.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            313..759
                     /locus_tag="VQ878_002132"
                     /pseudo
     CDS             313..759
                     /locus_tag="VQ878_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          251 a          141 c          156 g          211 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagttatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta
      241 tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg
      301 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
      361 cttgttggtg ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat
      421 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ctttcttatg
      481 gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
      541 atccacgaaa gcaacttaat ccgtcggagc cgatgggttg aagtaactct tgttcaaagt
      601 ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
      661 gaagtacaaa tcaatcgccc taaaaaaaca attagcgaat tattctggta aaaagaaatt
      721 tcacgctatg aagtctcaag cgattgtcac aagtcaagg
//
LOCUS       DAVBOM010000116          758 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBOM010000116 DAVBOM010000000
VERSION     DAVBOM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.117"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..>758
                     /locus_tag="VQ878_002133"
     CDS             <1..>758
                     /locus_tag="VQ878_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3096393.1"
                     /translation="DGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTS
                     SIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLI
                     ASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS
                     EQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          297 a          110 c          120 g          231 t
ORIGIN      
        1 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
       61 gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta
      121 tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata
      181 tctttcacct gaacaagcgc cttcccgtgc cagaaaatta gtttcgcaga atagtgtctt
      241 attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta
      301 tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa
      361 atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag
      421 ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc
      481 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
      541 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
      601 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
      661 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
      721 taaaaagaaa gatttggaca tttctattgt ttcccaag
//
LOCUS       DAVBOM010000117          677 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBOM010000117 DAVBOM010000000
VERSION     DAVBOM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.118"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            1..629
                     /locus_tag="VQ878_002134"
                     /pseudo
     CDS             1..629
                     /locus_tag="VQ878_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          228 a          119 c          136 g          194 t
ORIGIN      
        1 ttatgccacg tccagaacat cctaagaaag cagacgctca aaccattgtc gcgtctaaaa
       61 ataaaatttc aattcaagaa gaaaagaaag cgctttaaaa ccagtagacg ttttcataag
      121 gttcgcttga tgtaccaaga tgaggctggc ttcggtagaa tcagtaaact gggatcttgt
      181 tggtctccaa taggagtagg tccacatgtc catagtcact atatacgaga atttcgctat
      241 tgttatggac ccatacaggc gaatcatttt tcttaatagc tggtggatgt aatactgagt
      301 ggatgaacgt ctttttagaa gagctttcac aagcttatcc agatgattat cttttattcg
      361 ttatggacaa tgctatatgg cataaatcaa gtaccttaaa gattccgact aatattggct
      421 ttgcatttat tcctccatac acaccagaga tgaaccccat tgaacaagtg tggaaagaga
      481 ttcgtaaacg tggatttaaa aataaagcct ttcaaacttt ggaagatgtc atgaatcaac
      541 tttaagatat catacaagga ctggagaagg aggtgataaa gcccatcgtt aatcggagat
      601 ggactagaat gctttttgaa agcagatgag tataaaaaga aagtcctcat ttcaatagaa
      661 atcacgactt tctgatg
//
LOCUS       DAVBOM010000118          630 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBOM010000118 DAVBOM010000000
VERSION     DAVBOM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.119"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            47..408
                     /locus_tag="VQ878_002135"
                     /pseudo
     CDS             47..408
                     /locus_tag="VQ878_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
BASE COUNT          207 a           76 c          119 g          228 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt cattgagtat aacacattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaat atctgtaact gtaataggat attttgaaat aaatatagat
      241 gaaaatatca ccgatattct atacgtaaat ggtactgcta ttctttgtcc ttatttacgt
      301 tctattgttt caatagtttc ggcaattgat agcagtgaag caatgttgct acctaccatt
      361 aatgttttag agttactaga taaatctcaa ccttttgaag aagaataatt tattagctca
      421 ctaaattgag ggtaaggaaa agtaaaagca gtaagaaaaa tgtcttgcat tatacagcaa
      481 ccttttggga atgagtagat ggattgaata aaatttgatt aagagtggat gatttatctg
      541 tagattatta ttggacagtt agtcttgaag tagtctaaga attaggttat aatcagtaga
      601 agccttgcta ataatgagga ggttagttta
//
LOCUS       DAVBOM010000119          601 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBOM010000119 DAVBOM010000000
VERSION     DAVBOM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.120"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..>601
                     /locus_tag="VQ878_002136"
     CDS             <1..>601
                     /locus_tag="VQ878_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3096394.1"
                     /translation="FDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT          192 a          135 c          122 g          152 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa ccgccaatgg tgttgctgta ccgcacggag
       61 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccaa gtccgcaacc tgcaccaaat cctcaaccag
      241 ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg
      301 gttatgtctt tgaggagaat ggagttcctc gttatatccc agccaaggat ctttcagcag
      361 aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag
      421 gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag gcttatgact
      481 tactagcaag aattcatcaa gatttacttg ataataaagg tcgacaagtt gattttgagg
      541 ctttggataa cctgttggaa cgactcaagg atgtctcaag tgataaagtc aagttagtgg
      601 a
//
LOCUS       DAVBOM010000120          599 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBOM010000120 DAVBOM010000000
VERSION     DAVBOM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.121"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(21..500)
                     /locus_tag="VQ878_002137"
     CDS             complement(21..500)
                     /locus_tag="VQ878_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3096395.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          160 a          139 c           78 g          222 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat aaacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaactgca caaaaaaga
//
LOCUS       DAVBOM010000121          536 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBOM010000121 DAVBOM010000000
VERSION     DAVBOM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.122"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..534)
                     /locus_tag="VQ878_002138"
     CDS             complement(<1..534)
                     /locus_tag="VQ878_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3096396.1"
                     /translation="MEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIR
                     ANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKR
                     ERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPK
                     VDGPDFELIKKLCDAGVD"
BASE COUNT          141 a          133 c          103 g          159 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atcccaatga ttggaagttt
      361 agtgacttcc ttaatttcct tgatatcgcg aacactgttt gctcggatac cgactgctcc
      421 accttgctca gccgctttga ccagcaaggg aatcacccct cccgcttctg tataaagcgg
      481 ttcatgagga agagcctgac aagaaacgat gattccatct ttgatttgct caatca
//
LOCUS       DAVBOM010000122          501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBOM010000122 DAVBOM010000000
VERSION     DAVBOM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.123"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VQ878_002139"
     CDS             <1..>501
                     /locus_tag="VQ878_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3096397.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVBOM010000123          484 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBOM010000123 DAVBOM010000000
VERSION     DAVBOM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.124"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            1..484
                     /locus_tag="VQ878_002140"
                     /pseudo
     CDS             1..484
                     /locus_tag="VQ878_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT          147 a           96 c          105 g          136 t
ORIGIN      
        1 actcgactct ctccttcaag aaacacgtgg tggtcgtaac catgcatata tgacagttga
       61 ggaagagaaa gcctttcttg cccgccattt gaaggctaca gaggcaggag aatttgttac
      121 aattgatgcc ttatttcagg cttataaaaa ggagttaggt cattcctaca cacgtgatgc
      181 cttctatcaa ctgttgaagc gccatggttg gcgaaatatt acgccacgtc cagaacatcc
      241 taagaaagca gacgctcaaa ccattgttgc gtctaaaaat aaaatctcaa ttcaagaaga
      301 caagaaagcg ttttaaatat agtagacgtt ttcataaggt tcgcttgatg taccaagatg
      361 aggctggttt cggtagaatc agtaaactgg gatcttgttg gtctccaata ggagtaggtc
      421 cacatgtcca tagtcactat atacgagaat ttcgctatta ttatggagct gttgatgcct
      481 atac
//
LOCUS       DAVBOM010000124          476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBOM010000124 DAVBOM010000000
VERSION     DAVBOM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.125"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(91..228)
                     /locus_tag="VQ878_002141"
     CDS             complement(91..228)
                     /locus_tag="VQ878_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3096398.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            complement(372..446)
                     /locus_tag="VQ878_002142"
                     /pseudo
     CDS             complement(372..446)
                     /locus_tag="VQ878_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
BASE COUNT          170 a           79 c           69 g          158 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagcc ccaattattc acccctaatc taaaaa
//
LOCUS       DAVBOM010000125          381 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBOM010000125 DAVBOM010000000
VERSION     DAVBOM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.126"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>381)
                     /locus_tag="VQ878_002143"
     CDS             complement(<1..>381)
                     /locus_tag="VQ878_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3096399.1"
                     /translation="KTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETL
                     YQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKE
                     MKEGFFGDKTDSSTLIKNEVRMMMS"
BASE COUNT           96 a           81 c           88 g          116 t
ORIGIN      
        1 gctcatcatc atacgaactt cgtttttgat taaggttgaa ctatccgttt tatcgccaaa
       61 aaatccctcc ttcatctcct tgatgaaatt ctcggcttga ccacgtccac gataaagctg
      121 aaactggtct tggcttgttc cactcgtcat atttgtaacg agagaaataa catcgtagaa
      181 caagtttcct tcttttcgtt cagagaactg gcagacacga cgcttgtgcg accaagatcc
      241 tgcttgatag agagtttctg agtaggcgga gtggggcaag atggttaagt cctcatcctg
      301 tgggcaaggg agggaaaggt ctccaagacg gctcagaaca gtatttttct tgagttttat
      361 gaggtagtat tgccctgttt t
//
LOCUS       DAVBOM010000126          377 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBOM010000126 DAVBOM010000000
VERSION     DAVBOM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.127"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ878_002144"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ878_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          100 a           67 c           71 g          139 t
ORIGIN      
        1 agtacttact ggaatggcaa attcagtcac atctgtgtag cactgttcca ttgttttaga
       61 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttaatgag
      121 aagaatattt tcgtttctgt cgcgttttag cttgtaaatt gagtactttc atcaagcctt
      181 gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga atacagcgat
      241 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
      301 ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtccaacga gctagtttaa
      361 tagcttttag aagaaga
//
LOCUS       DAVBOM010000127          297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBOM010000127 DAVBOM010000000
VERSION     DAVBOM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.128"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            116..>297
                     /locus_tag="VQ878_002145"
     CDS             116..>297
                     /locus_tag="VQ878_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HET3096400.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCR"
BASE COUNT           95 a           57 c           49 g           96 t
ORIGIN      
        1 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
       61 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcacatgaa
      121 cagtttacca aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg
      181 tcatttaacc cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact
      241 aaaagagcgg atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgtta
//
LOCUS       DAVBOM010000128          284 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVBOM010000128 DAVBOM010000000
VERSION     DAVBOM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.129"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
BASE COUNT           86 a           55 c           79 g           64 t
ORIGIN      
        1 tctgaggtgt aagtcctcgg tgggcacctg ttaccggtga acccaatagc gattcccaag
       61 cctgactatc gtgaggtagc ggattaaaac ggtctgggga tagaccgttt taaatctgac
      121 gctggaaata agaatcgtca gaggaaggga tagcgaactc gtggctctac gaacaggaac
      181 gtgatagtaa ggcgtatata gcggataagg gggcctcaaa ctctaaagtt caaaaaggta
      241 gtcgtaacct atatgcgtaa atcacgagag caactgaatt tgtc
//
LOCUS       DAVBOM010000129          253 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVBOM010000129 DAVBOM010000000
VERSION     DAVBOM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.130"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>253)
                     /locus_tag="VQ878_002146"
     CDS             complement(<1..>253)
                     /locus_tag="VQ878_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HET3096401.1"
                     /translation="SEIIAYNLSCSPNLEQVQTMLEQAFKEKHYENTILHSDQGCQYQ
                     HDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEM"
BASE COUNT           66 a           49 c           51 g           87 t
ORIGIN      
        1 acatttcgga ttttaaaatg ccaaagaaag attccatcat accgttgtct tggctgtttc
       61 ccttgcgtga catggatgct tgaattccct tactctctag gaaccgatga taagaatcgt
      121 gttggtattg acagccttgg tcactatgga gaatcgtatt ctcatagtgc ttctctttga
      181 atgcctgttc caacattgtt tgtacttgtt ctaaattagg cgaacaagaa agattatagg
      241 cgataatttc gct
//
LOCUS       DAVBOM010000130          251 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVBOM010000130 DAVBOM010000000
VERSION     DAVBOM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.denovo.131"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..>251
                     /locus_tag="VQ878_002147"
     CDS             <1..>251
                     /locus_tag="VQ878_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3096402.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKG"
BASE COUNT           84 a           51 c           60 g           56 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgagagag cggcagccca ggcttatgct
      241 aaagagaaag g
//
LOCUS       DAVBOM010000131        10365 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 42-05
            SAMEA1012555-rid20182173.guided.069, whole genome shotgun sequence.
ACCESSION   DAVBOM010000131 DAVBOM010000000
VERSION     DAVBOM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012555
            Sequence Read Archive: ERR046720
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979939.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979939.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:42:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,158
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,985
            CDSs (with protein)               :: 1,985
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 79 of 129
            Pseudo Genes (incomplete)         :: 48 of 129
            Pseudo Genes (internal stop)      :: 34 of 129
            Pseudo Genes (multiple problems)  :: 27 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012555-rid20182173.guided.069"
                     /strain="NIG 42-05"
                     /db_xref="taxon:1313"
     gene            <1..2002
                     /locus_tag="VQ878_002148"
     CDS             <1..2002
                     /locus_tag="VQ878_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3096403.1"
                     /translation="SRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNFI
                     WTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLLL
                     LILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDIS
                     NASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRVE
                     SLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFVF
                     LLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLIIT
                     TAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRVM
                     RKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGKE
                     KSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRDL
                     TSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQYH
                     DEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTTA
                     DRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            1999..3000
                     /locus_tag="VQ878_002149"
     CDS             1999..3000
                     /locus_tag="VQ878_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3096404.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            2997..3932
                     /locus_tag="VQ878_002150"
     CDS             2997..3932
                     /locus_tag="VQ878_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3096405.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            4177..4293
                     /locus_tag="VQ878_002151"
     CDS             4177..4293
                     /locus_tag="VQ878_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3096406.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            4309..6228
                     /gene="tet(M)"
                     /locus_tag="VQ878_002152"
     CDS             4309..6228
                     /gene="tet(M)"
                     /locus_tag="VQ878_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3096407.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            6347..6514
                     /locus_tag="VQ878_002153"
     CDS             6347..6514
                     /locus_tag="VQ878_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3096408.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(6574..6927)
                     /locus_tag="VQ878_002154"
     CDS             complement(6574..6927)
                     /locus_tag="VQ878_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3096409.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            7432..7854
                     /locus_tag="VQ878_002155"
     CDS             7432..7854
                     /locus_tag="VQ878_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3096410.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            7851..8081
                     /locus_tag="VQ878_002156"
     CDS             7851..8081
                     /locus_tag="VQ878_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3096411.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            8542..8745
                     /locus_tag="VQ878_002157"
     CDS             8542..8745
                     /locus_tag="VQ878_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3096412.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            8827..10044
                     /locus_tag="VQ878_002158"
     CDS             8827..10044
                     /locus_tag="VQ878_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3096413.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3475 a         1840 c         2093 g         2957 t
ORIGIN      
        1 cagccgatac ccacttgaaa actatcaact ggatttttat gtggataata gctggggctg
       61 gcttccgtgg aactggtcgg acgggattgg aaaacaggtc atgtatggac tatatgccat
      121 taccaatttt atttggacaa tcagtttgta tgtttccaat gcgacaggtt acttagtaca
      181 ggaagcctat tccttagact tcatttccgc tacagcagat tccattggta agaatatgca
      241 gaccttagct ggtgtgagtg caaacggatt ttcaacagag ggtttctatg ttggattcct
      301 cttactcttg attttggttc ttggggttta tgttgcctat acgggactga taaagagaga
      361 aaccacaaag gcaattcatg ccattatgaa ttttgtgctg gtgtttatcc tatcggcttc
      421 ctttattgcc tacgctcccg actacattaa aaaaatcaat gacttttcat cagacatcag
      481 taatgccagt ttatcacttg gcacgaagat tgtcatgccc cattccgata gtcaaggcaa
      541 ggacagcgtg gacttaatca gagatagcct gttttccata caggttcagc aaccgtggct
      601 actgcttcaa tacaacagtt cagacattga aagtatcggt attgaccgtg tggaaagcct
      661 gctctccacc agcccagatt ccaacaatgg cgaagacaga gaaaaaattg ttgcggaaga
      721 aattgaagac agaagcaata ccaatctaac cattacaaag accattaacc gtttaggtac
      781 agtcttcttc ctatttgtct tcaatattgg gatttccata tttgtattcc tattaacagg
      841 aatcatgatt ttctcgcagg tactttttat catctatgct atgtttctgc ctgtgagctt
      901 tattttaagc atgattccat catttgatgg tatgtcaaaa cgagccataa caaagctctt
      961 taataccatt ttgacacgag ctggaatcac attgattatt acgacagcat ttagtatttc
     1021 aaccatgctc tataccttat cggctggtta tccgttcttt ttgattgctt ttctacagat
     1081 tgtgaccttt gcaggaatct acttcaagct gggcgattta atgagtatgt tttctctaca
     1141 gagtaacgat tctcaaagtg tgggaagtcg tgtgatgaga aaacctcgta tgcttatgca
     1201 cgctcacatg caccgtctac agcggaaact tggacgttcc atgactactc taggggctgg
     1261 gtctgccatt gttacaggta aaaaaggaca gtcgggttcg gggagttctg caaggacaca
     1321 agcagatcac tcccgaccag acggaaagga aaaatcaaca cttggaaaac gtatcggtca
     1381 aaccatcggt acagtagctg ataccaaaga cagaatggta gacactgcta gtggtttgaa
     1441 agaacaggtt aaagatttgc cgaccaatgc aagatatgca gtatatcaag gaaaatccaa
     1501 agtaaaagag aatgtccgtg atttaaccag tagtatttct caaaccaaag cggacagagc
     1561 cagtggacgc aaggaacagc aggaacaaag gcgaaaaacc attgcgaagc gtcgctctga
     1621 aatggaacag gtcaaacaga aaaaacagcc tgcttcttct gttcatgaaa gaccgactac
     1681 aagacaagaa caatatcatg atgaacagac ctcaaaacag tctaatattc agacttcata
     1741 taaggaatct caacaagcca aacaagagcg tccagcagtt aagtccgatt tttcaagtcc
     1801 aaaagtggaa cgccaaggca ataccgttca agaaaaaacc gttcaaaagc cagcaacttc
     1861 aaccactaca gcagatagaa cttcacaacg tccaatcaca aaagaacgtc cgtctactgt
     1921 tcaaagagta ccactacaaa atacaagaag tagaccacca atcaaaaccg ccaccattaa
     1981 gaaagtcggt aagaaaccat gaagttgaaa actttagtga ttggtggttc tggattattc
     2041 ttgatggtct tctcactgct tctgtttgtt gccattttat tttcagatga acaggacagc
     2101 ggaatttcca atattcatta tggaggtgtg aatgtttccg cagaagtgct ggctcataag
     2161 cctatggtag aaaaatatgc caaagaatat ggcgttgaag aatatgtcaa catacttctt
     2221 gcgattatac aggtggaatc gggcggtact gcggaagatg ttatgcagtc ctcggaatcc
     2281 ctcggtcttc cacctaattc attgagtaca gaagaatcca ttaagcaagg tgtgaagtat
     2341 ttcagtgaat tattagccag tagcgaaagg ctcagtgtag atttagaatc ggttatccag
     2401 tcctacaatt atggtggtgg tttcttaggg tatgtggcta atcgtggaaa taaatatacc
     2461 tttgaactgg ctcaaagttt ctcaaaagag tattcaggtg gcgaaaaagt gtcttacccc
     2521 aatcccatag ccatacctat caatgggggc tggcgataca actatggcaa tatgttttat
     2581 gtgcaactgg taacgcagta tcttgtcaca acagagtttg atgatgatac ggtacaagcc
     2641 atcatggacg aagcactgaa atatgagggc tggcgatacg tttacggtgg agcttccccg
     2701 actacttctt ttgattgtag cggactgaca caatggacgt atggaaaagc tggaattaac
     2761 ttaccacgaa ccgcacaaca gcaatatgat gtgacccagc atatcccact atcggaagca
     2821 caagctggcg atttggtttt ctttcattct acctataacg ctggctctta tattactcat
     2881 gttgggatat accttggcaa taaccgtatg tttcatgcag gcgacccaat cggttatgcc
     2941 gacttaacaa gcccctactg gcaacagcat ttagtgggag caggacgaat caaacaatga
     3001 gaaaggaaga tttaatgatg aaatttagaa aaaatcagaa taaagaaaaa cagataccaa
     3061 aggaaaagaa acctcgtgtc tactataagg tcaatcctca taaaaaggtt gtgattgcct
     3121 tgtgggtact tttagggctt agtttcagct ttgcgatatt caagcacttt acagctatag
     3181 atactcatac tattcacgaa acaactatca tagaaaagga atacgttgat actcatcatg
     3241 tagaaaattt tgtagagaac tttgcgaaag tctactattc atgggagcaa tccgataagt
     3301 ccattgataa tcgaatggaa agtctaaaag gctatctgac agatgaactt caagctctca
     3361 atgttgatac agtacgcaaa gatattcctg tatcgtcttc tgtaagagga tttcagatat
     3421 ggacggtaga gccaactggc gacaatgagt ttaatgtaac ctacagtgta gaccagctca
     3481 ttacagaggg agaaaataca aagaccgtcc actctgctta tatagtgagt gtctatgtag
     3541 atggttctgg aaatatggta ctggttaaga atccgaccat taccaacata cctaagaaat
     3601 caagttataa accaaaagcc attgaaagtg aggggacggt tgattccatt acaaccaatg
     3661 aaatcaatga gtttttaacg acgttcttca agctctatcc tacagcgaca gccagtgaac
     3721 tttcctacta tgtgaatgac gggatattaa aaccaatcgg aaaagagtac atctttcaag
     3781 aactggtaaa tcctattcac aatcgtaagg ataatcaagt cacggtatcg ctgacagtgg
     3841 agtatatcga ccagcagacc aaagcaacgc aggtatctca atttgatttg gtacttgaaa
     3901 agaacgggag taattggaag attatagaat aacaaatatt ggtacattat tacagctatt
     3961 ttgtaatcac gtactctctt tgataaaaaa ttggagattc ctttacaaat atgctcttat
     4021 gtgctattat ttaagtatct atttaaaagg agttaataaa tatgcggcaa ggtattctta
     4081 aataaactgt caatttgata gtggaaacaa ataattggat gtcctttttt aggagggctt
     4141 agttttttgt acccagttta agaatacctt tatcatgtga ttctaaagta tccggagaat
     4201 atctgtatgc tttgtatgcc tatggttatg cataaaaatc ccagtgataa gagtatttat
     4261 cactgggatt tttatgccct tttgggcttt tgaatggagg aaaatcacat gaaaattatt
     4321 aatattggag ttttagctca tgttgatgcg ggaaaaacta ccttaacaga aagcttatta
     4381 tataacagtg gagcgattac agaattagga agcgtggaca gaggtacaac gaaaacggat
     4441 aatacgcttt tagaacgtca gagaggaatt acaattcaga cggcgataac ctcttttcag
     4501 tggaaaaata ctaagataaa catcatagac acgccaggac atatggattt tttagcagaa
     4561 gtatatcgtt cattatcagt attagatggg gcaattctac tgatttctgc aaaagatggc
     4621 gtacaagcac aaactcgtat attgtttcat gcacttagga aaataggtat tcccacaatc
     4681 ttttttatca ataagattga ccaaaatgga attgatttat caacggttta tcaggatatt
     4741 aaagagaaac tttctgcgga aattgtaatc aaacagaagg tagaactgca tcctaatatg
     4801 cgtgtaatga actttaccga atctgaacaa tgggatatgg taatagaagg aaatgattac
     4861 cttttggaga aatatacgtc tgggaaatta ttggaagcat tagaactcga acaagaggaa
     4921 agcataagat ttcataattg ttccctgttc cctgtttatc acggaagtgc aaaaaacaat
     4981 atagggattg ataaccttat agaagtgatt acgaataaat tttattcatc aacacatcga
     5041 ggtcagtctg aactttgcgg aaaagttttc aaaattgagt attcggaaaa aagacagcgt
     5101 cttgcatata tacgtcttta tagtggcgta ctgcatttgc gagattcggt tagaatatcg
     5161 gaaaaggaaa aaataaaaat tacagaaatg tatacttcaa taaatggtga attatgtaaa
     5221 atcgataagg cttattccgg ggaaattgtt attttgcaga atgagttttt gaagttaaat
     5281 agtgttcttg gagatacaaa gctattgcca cagagagaga gaattgaaaa tcccctccct
     5341 ctgctgcaaa cgactgttga accgagcaaa cctcaacaaa gggaaatgtt acttgatgca
     5401 cttttagaaa tctccgacag tgacccgctt ctgcgatatt atgtggattc tgcgacacat
     5461 gaaatcatac tttctttctt agggaaagta caaatggaag tgacttgtgc tctgctgcaa
     5521 gaaaagtatc atgtggagat agaaataaaa gagcctacag tcatttatat ggaaagaccg
     5581 ttaaaaaaag cagagtatac cattcacatc gaagttccac cgaatccttt ctgggcttcc
     5641 attggtctat ctgtagcacc gcttccatta gggagcggag tacagtatga gagctcggtt
     5701 tctcttggat acttaaatca atcgtttcaa aatgcagtta tggaggggat acgctatggc
     5761 tgtgaacaag gattgtatgg ttggaatgtg acggactgta aaatctgttt taagtatggc
     5821 ttatactata gccctgttag taccccagca gattttcgga tgcttgctcc tattgtattg
     5881 gaacaagtct taaaaaaagc tggaacagaa ttgttagagc catatcttag ttttaaaatt
     5941 tatgcgccac aggaatatct ttcacgagca tacaacgatg ctcctaaata ttgtgcgaac
     6001 atcgtagaca ctcaattgaa aaataatgag gtcattctta gtggagaaat ccctgctcgg
     6061 tgtattcaag aatatcgtag tgatttaact tcctttacaa atggacgtag tgtttgttta
     6121 acagagttaa aagggtacca tgttactacc ggtgaacctg tttgccagcc ccgtcgtcca
     6181 aatagtcgga tagataaagt acgatatatg ttcaataaaa taacttagtg tattttatgt
     6241 tgttatataa atatggtttc ttgttaaata agatgaaata ttttttaata aagatttgaa
     6301 ttaaagtgta aaggaggaga tagttattat aaactacaag tggatattgt gtcctgtatg
     6361 tggaaataaa acacgattaa agataaggga agatactgaa ttaaaaaaat tccccctcta
     6421 ttgtccgaaa tgcagacaag aaaatttaat tgaaataaag cagttcaaag taactgtgat
     6481 tacagagcca gacgcaaaga cgcagagccg ataaaatgag attaatacaa tctcatttta
     6541 tcggctcttt ccgttatgta tggattcttt taattagtct tcgatgtttc ttgcttcgtt
     6601 gataccgctg gctaaagatt ccattaagga tagttctttg tctgtaaagc tatccatgta
     6661 tttctctatc tgtaatcgtc gggtgctttt taccaagtta ttagcaggta agaaaaattc
     6721 atcaacggaa acatgaagta acgatacaag gtcataaaga acttgtatgc tggggtgttg
     6781 ccctttattt tcaatattag ttaagtaccg tgggtcaatt tcaatcaatg ctcccacttg
     6841 ttcacgagtt aaacctcgtt tcaatcgagc ttctttaatg gctaaaccaa aggctctaaa
     6901 atcatattta tcttcttttt tacgcatagt agaccacctc tatacatttt attgttccta
     6961 ctgaattaaa aacaggtata gaaaaacgtg ttatatggtt tataggttta tatttaataa
     7021 aaagcactac taaacgccaa taaaaaaaac cgttatatgg tagtgctatt tacgctgtta
     7081 aaatattgta tattacttcc aaatggcggt ttgttggagg tcaacgtcgc catgaagtac
     7141 atcatataca ataaatttcc ttacattggg ttcttgtcaa aaaaagtcgt ctatctgcaa
     7201 tagataagta cgtccaccaa tgtggtttta taaatcatat agatagaata acagaagcat
     7261 gtaaacagag aaataaatct gtttatatgc ttttttggct attcagaact tttttacaaa
     7321 gtttatttat cagtaatgca acaaatcccc ctttcacatt gggactaaga gtgaaaggag
     7381 ataaacgagc aaggctcact tcctttccta gacagaaagg gggtgagaaa catgaaacca
     7441 tcttcttttc agaccacaat agaaaatcag tttgactata tctgtaaacg tgctatggaa
     7501 gacgagcgaa agaattatat gctttatctt tcaaggattg caaagcgtga ggtgtccttt
     7561 tcggatgttg gcgattatct tgttagccag tttgcgacaa cagataacta ttcaactgac
     7621 tttcagattt ttacactcaa tgggttatca gtaggcgttg aaaatgattt gttgagtgaa
     7681 gcattacgtg agttgccaga caagaaacgt gaaattctac tgctgtttta ctttatggac
     7741 atgagcgatt cagaaattgc agacctgttg aaattgaacc gttctactgt ctatcggcat
     7801 agaaccagtg gactagcctt aattaaaaag tttatggagg aatttgaaga atgaaaacac
     7861 aatatcctat gattcccttt cctctcattg taaaggcaac agatggcgat accgaagcga
     7921 ttaaccagat tctacatcat tacagagggt acataacgaa gcgttcccta cgacttatga
     7981 aagatgaata tggcaatcaa agtatggtcg ttgatgaagt cttacgtgga agaatggaaa
     8041 ccagactgat tacaaagatt ttgtcatttg aaattaagta atatcctctc tcctttcgtg
     8101 gaagcgtgct aaaccattcc acgcttcccg aacagggagg tttgttattc caccaaagca
     8161 tattgagctt tcaatgtgtt ttgataggct aacgagccat tgttctttga aaactgaata
     8221 aaagtaatcg aatacgtttc gataagaaaa gagccaacgg aactaaccgc catgacctat
     8281 cttataaaga tagcgagcga ttcatgttag tgatccgaga agcaatcttt agcaggattg
     8341 cctgcaacga cattcttatc gtgataatga tactcccata cagtcaatag tccgagcgtg
     8401 ataaaaccgt cgcaggcaat gagtatggct acatgagaac catgcagggg tggaactccc
     8461 gtgagctttg ctaaagctgt tcgattgctg gtaaaacaac ttttatgaaa tccaaataag
     8521 tgatttggaa aggaggattt tatgaagcag actgacattc ctatttggga acgttatacc
     8581 ctaaccattg aagaagcgtc aaaatatttt cgtattggcg aaaacaagct acgacgcttg
     8641 gcagaggaaa ataaaaatgc aaattggctg attatgaatg gcaatcgtat tcagattaaa
     8701 cgaaaacaat ttgaaaaaat tatagataca ttggacgcaa tctagcgtcg ccaaagggtc
     8761 ttgtatatga taaaatagta ttaagtcgta tcaaggctct ttccataaag gaaaggagca
     8821 aatgccatgt cagaaaaaag acgtgacaat aaaggtcgaa tcttaaagac tggagagagc
     8881 caacgaaaag acggaagata cttatacaaa tatatagatt catttggaga accgcaattt
     8941 gtttactcgt ggaaacttgt ggctacagac cgagtaccag caggaaagcg tgattgtatc
     9001 tcacttagag agaaaatcgc agagttacag aaagacattc atgatggtat tgatgttgta
     9061 ggaaagaaaa tgacactctg ccagctttac gcaaaacaga acgctcaaag accaaaggtt
     9121 agaaaaaaca ctgaaactgg acgcaaatat cttatggata ttttgaagaa agacaagtta
     9181 ggtgtaagaa gtattgacag tattaagcca tcagacgcta aagaatgggc tattagaatg
     9241 agtgaaaatg gttatgctta tcaaaccatc aataactaca aacgttcttt aaaggcttca
     9301 ttctatattg ctatacaaga tgattgtgtt cggaagaatc catttgactt tcaactgaaa
     9361 gcagttcttg atgatgatac tgtccctaag accgtactaa cagaagaaca ggaagaaaaa
     9421 ctgttagcct ttgcaaaagc tgataaaacc tacagcaaaa attatgatga aattctgata
     9481 ctcttaaaaa caggtcttcg tatttcagag tttggtggtt tgacacttcc agatttagat
     9541 tttgagaatc gtcttgtcaa tatagaccat cagctattga gagatactga aattgggtac
     9601 tacattgaaa caccaaagac caaaagtggc gaacgtcaag ttcctatggt tgaagaagcc
     9661 tatcaagcat ttaagcgagt gttagcgaat cgaaagaatg ataagcgtgt tgagattgat
     9721 ggatatagtg atttcctctt tcttaataga aagaactatc caaaagtggc aagtgattac
     9781 aacggcatga tgaaaggtct tgttaagaaa tacaataagt ataacgagga taaattgcca
     9841 cacatcactc cacatagttt gcgacataca ttctgtacca actatgcaaa tgcaggaatg
     9901 aatccaaagg cattacagta cattatggga catgctaata tagccatgac gctgaactat
     9961 tacgcacatg caacattcga ttctgcaatg gcagaaatga aacgcttgaa taaagagaag
    10021 caacaggagc gtcttgttgc ttagtagtac aaatgaattt actacttatt taccacttct
    10081 gacagctaag acatgaggaa atatgcaaag aaacgtgaag tatcttccta cagtaaaaat
    10141 actcgaaagc acatagaata aggctttacg agcatttaag aaaatataaa aagataatta
    10201 gaaatttata ctttgttttt attaaaaagc agcaaactat aaactagtag gttccacact
    10261 aaatgtagcc ccatactgcc ccacaagtcc gatttatagc gtaccatccc taaaaacatt
    10321 cccaatgaaa catataaaca ccaagctaga atggttcctg gatga
//
